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1.	Abazov, V. M., et al. (författare) The upgraded DO detector 2006 Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 565:2, s. 463-537 Tidskriftsartikel (refereegranskat)abstract The DO experiment enjoyed a very successful data-collection run at the Fermilab Tevatron collider between 1992 and 1996. Since then, the detector has been upgraded to take advantage of improvements to the Tevatron and to enhance its physics capabilities. We describe the new elements of the detector, including the silicon microstrip tracker, central fiber tracker, solenoidal magnet, preshower detectors, forward muon detector, and forward proton detector. The uranium/liquid -argon calorimeters and central muon detector, remaining from Run 1, are discussed briefly. We also present the associated electronics, triggering, and data acquisition systems, along with the design and implementation of software specific to DO.
2.	Abazov, V. M., et al. (författare) Measurement of the t(t)over-bar production cross section in p(p)over-bar collisions at root s=1.96 TeV using secondary vertex b tagging 2006 Ingår i: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 1550-7998 .- 1550-2368. ; 74:11, s. 112004- Tidskriftsartikel (refereegranskat)abstract We report a new measurement of the t (t) over bar production cross section in p (beta) over bar collisions at a center-of-mass energy of 1.96 TeV using events with one charged lepton (electron or muon), missing transverse energy, and jets. Using 425 pb(-1) of data collected using the D0 detector at the Fermilab Tevatron Collider, and enhancing the t (t) over bar content of the sample by tagging b jets with a secondary vertex tagging algorithm, the t (t) over bar production cross section is measured to be sigma(p (t) over bar -> t (t) over bar +X)=6.6 +/- 0.9(stat+syst) +/- 0.4(lum) pb. This cross section is the most precise D0 measurement to date for t (t) over bar production and is in good agreement with standard model expectations.
3.	Carré, B., et al. (författare) Characterization of attosecond pulse trains 2007 Ingår i: Ultrafast Optics V. - New York, NY : Springer New York. - 1556-1534 .- 0342-4111. - 9780387491172 ; 132, s. 45-56 Konferensbidrag (refereegranskat)abstract Ultrashort light pulses, as short as 100 as, can be produced from high harmonic generation (HHG) in an atomic gas medium. This major achievement of the last 6 years in high field physics has now been demonstrated in different conditions of medium-field interaction [1].
4.	Arnold, C. L., et al. (författare) The ELI-ALPS secondary sources : A getaway to scientific excellence 2013 Ingår i: 2013 Conference on Lasers and Electro-Optics, CLEO 2013. - 9781557529725 ; 2013 Konferensbidrag (refereegranskat)abstract The essence of ELI-ALPS, the laser driven secondary sources ranging from X-ray and X-UV to THz with duration as short as tens of attoseconds, are designed to be available for users from 2016.
5.	Iablonskyi, D., et al. (författare) Slow Interatomic Coulombic Decay of Multiply Excited Neon Clusters 2016 Ingår i: Physical Review Letters. - 0031-9007. ; 117:27 Tidskriftsartikel (refereegranskat)abstract Ne clusters (∼5000 atoms) were resonantly excited (2p→3s) by intense free electron laser (FEL) radiation at FERMI. Such multiply excited clusters can decay nonradiatively via energy exchange between at least two neighboring excited atoms. Benefiting from the precise tunability and narrow bandwidth of seeded FEL radiation, specific sites of the Ne clusters were probed. We found that the relaxation of cluster surface atoms proceeds via a sequence of interatomic or intermolecular Coulombic decay (ICD) processes while ICD of bulk atoms is additionally affected by the surrounding excited medium via inelastic electron scattering. For both cases, cluster excitations relax to atomic states prior to ICD, showing that this kind of ICD is rather slow (picosecond range). Controlling the average number of excitations per cluster via the FEL intensity allows a coarse tuning of the ICD rate.
6.	Sanchez-Gonzalez, A., et al. (författare) Auger electron and photoabsorption spectra of glycine in the vicinity of the oxygen K-edge measured with an X-FEL 2015 Ingår i: Journal of Physics B-Atomic Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 48:23 Tidskriftsartikel (refereegranskat)abstract We report the first measurement of the near oxygen K-edge auger spectrum of the glycine molecule. Our work employed an x-ray free electron laser as the photon source operated with input photon energies tunable between 527 and 547 eV. Complete electron spectra were recorded at each photon energy in the tuning range, revealing resonant and non-resonant auger structures. Finally ab initio theoretical predictions are compared with the measured above the edge auger spectrum and an assignment of auger decay channels is performed.
7.	Takanashi, T, et al. (författare) Time-Resolved Measurement of Interatomic Coulombic Decay Induced by Two-Photon Double Excitation of Ne2 2017 Ingår i: Physical Review Letters. - 0031-9007. ; 118:3 Tidskriftsartikel (refereegranskat)abstract The hitherto unexplored two-photon doubly excited states [Ne∗(2p-13s)]2 were experimentally identified using the seeded, fully coherent, intense extreme ultraviolet free-electron laser FERMI. These states undergo ultrafast interatomic Coulombic decay (ICD), which predominantly produces singly ionized dimers. In order to obtain the rate of ICD, the resulting yield of Ne2+ ions was recorded as a function of delay between the extreme ultraviolet pump and UV probe laser pulses. The extracted lifetimes of the long-lived doubly excited states, 390(-130/+450) fs, and of the short-lived ones, less than 150 fs, are in good agreement with ab initio quantum mechanical calculations.
8.	Varju, Katalin, et al. (författare) Reconstruction of attosecond pulse trains using an adiabatic phase expansion 2005 Ingår i: Physical Review Letters. - 1079-7114. ; 95:24 Tidskriftsartikel (refereegranskat)abstract We propose a new method to reconstruct the electric field of attosecond pulse trains. The phase of the high-order harmonic emission electric field is Taylor expanded around the maximum of the laser pulse envelope in the time domain and around the central harmonic in the frequency domain. Experimental measurements allow us to determine the coefficients of this expansion and to characterize the radiation with attosecond accuracy over a femtosecond time scale. The method gives access to pulse-to-pulse variations along the train, including the timing, the chirp, and the attosecond carrier envelope phase.
9.	Went, M, et al. (författare) Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma 2019 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10:1, s. 213- Tidskriftsartikel (refereegranskat)abstract The original version of this Article contained an error in the spelling of a member of the PRACTICAL Consortium, Manuela Gago-Dominguez, which was incorrectly given as Manuela Gago Dominguez. This has now been corrected in both the PDF and HTML versions of the Article. Furthermore, in the original HTML version of this Article, the order of authors within the author list was incorrect. The PRACTICAL consortium was incorrectly listed after Richard S. Houlston and should have been listed after Nora Pashayan. This error has been corrected in the HTML version of the Article; the PDF version was correct at the time of publication.
10.	Went, M, et al. (författare) Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma 2018 Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1, s. 3707- Tidskriftsartikel (refereegranskat)abstract Genome-wide association studies (GWAS) have transformed our understanding of susceptibility to multiple myeloma (MM), but much of the heritability remains unexplained. We report a new GWAS, a meta-analysis with previous GWAS and a replication series, totalling 9974 MM cases and 247,556 controls of European ancestry. Collectively, these data provide evidence for six new MM risk loci, bringing the total number to 23. Integration of information from gene expression, epigenetic profiling and in situ Hi-C data for the 23 risk loci implicate disruption of developmental transcriptional regulators as a basis of MM susceptibility, compatible with altered B-cell differentiation as a key mechanism. Dysregulation of autophagy/apoptosis and cell cycle signalling feature as recurrently perturbed pathways. Our findings provide further insight into the biological basis of MM.
11.	Andersen, J., et al. (författare) The soft X-ray laser project at MAX IV 2017 Ingår i: IPAC 2017 - Proceedings of the 8th International Particle Accelerator Conference. - : Joint Accelerator Conferences Website - JACoW. - 9783954501823 ; , s. 2760-2762 Konferensbidrag (refereegranskat)abstract A Soft X-ray Laser (SXL) beamline utilising FEL technology is being designed for the Short Pulse Facility (SPF) at the MAX IV Laboratory. A conceptual design study has been started following on the scientific case already prepared in collaboration between several Swedish Universities and driven by a strong (Swedish) user demand. The baseline goal of the SXL beamline is to generate intense and short pulses in the range 1-5 nm (0.2-1 keV). The system is building on the MAX IV linac system, already today providing 100 fs 3 GeV and pulses compressed to 100 fs for other applications within the SPF. As a special feature we foresee a variety of pump-probe capabilities.
12.	Barillot, T., et al. (författare) Angular asymmetry and attosecond time delay from the giant plasmon resonance in C60 photoionization 2015 Ingår i: Physical Review A. Atomic, Molecular, and Optical Physics. - 1050-2947 .- 1094-1622. ; 91 Tidskriftsartikel (refereegranskat)abstract This combined experimental and theoretical study demonstrates that the surface plasmon resonance in C 60 alters the valence photoemission quantum phase, resulting in strong effects in the photoelectron angular distribution and emission time delay. Electron momentum imaging spectroscopy is used to measure the photoelectron angular distribution asymmetry parameter that agrees well with our calculations from the time-dependent local density approximation (TDLDA). Significant structure in the valence photoemission time delay is simultaneously calculated by TDLDA over the plasmon active energies. Results reveal a unified spatial and temporal asymmetry pattern driven by the plasmon resonance and offer a sensitive probe of electron correlation. A semiclassical approach facilitates further insights into this link that can be generalized and applied to other molecular systems and nanometer-sized metallic materials exhibiting plasmon resonances.
13.	Curbis, F., et al. (författare) Status of the soft X-ray laser (SXL) project at the Max IV laboratory 2019 Ingår i: Proceedings of the 39th International Free-Electron Laser Conference, FEL 2019. - : JACoW Publishing. - 9783954502103 ; , s. 749-752 Konferensbidrag (refereegranskat)abstract A Soft X-ray Laser project (the SXL) aiming to produce FEL radiation in the range of 1 to 5 nm is currently in a conceptual design phase and a report on the design is expected to be delivered by March 2021. The FEL will be driven by the existing 3 GeV linac at MAX IV laboratory, which also serves as injector for the two storage rings. The science case has been pushed by a large group of mainly Swedish users and consists of experiments ranging from AMO physics to condensed matter, chemistry and imaging in life science. In this contribution, we will present the current conceptual design of the accelerator and the FEL operation modes together with a general overview of the beamline and experimental station. In particular design options for the FEL will be discussed in conjunction with the features of the electron beam from the MAX IV linac and the connection with the proposed experiments.
14.	Düsterer, S., et al. (författare) Angle resolved photoelectron spectroscopy of two-color XUV-NIR ionization with polarization control 2016 Ingår i: Journal of Physics B: Atomic, Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 49:16 Tidskriftsartikel (refereegranskat)abstract Electron emission caused by extreme ultraviolet (XUV) radiation in the presence of a strong near infrared (NIR) field leads to multiphoton interactions that depend on several parameters. Here, a comprehensive study of the influence of the angle between the polarization directions of the NIR and XUV fields on the two-color angle-resolved photoelectron spectra of He and Ne is presented. The resulting photoelectron angular distribution strongly depends on the orientation of the NIR polarization plane with respect to that of the XUV field. The prevailing influence of the intense NIR field over the angular emission characteristics for He(1s) and Ne(2p) ionization lines is shown. The underlying processes are modeled in the frame of the strong field approximation (SFA) which shows very consistent agreement with the experiment reaffirming the power of the SFA for multicolor-multiphoton ionization in this regime.
15.	Ericsson, Ingegerd, 1951-, et al. (författare) Att skolans idrottsundervisning inte nämns med ett ord är märkligt 2021 Ingår i: Sydsvenskan. - 1652-814X. ; :20210726 Tidskriftsartikel (populärvet., debatt m.m.)abstract Elever och föräldrar: Protestera när idrottsundervisning ersätts av rastaktivitet eller promenader. Promenader har visat sig vara den fysiska aktivitet som elever tycker allra minst om. Det skriver tio personer, forskare och andra som arbetar professionellt med barns och ungdomars hälsa.
16.	Ganguly, S., et al. (författare) Coincidence study of core-ionized adamantane: site-sensitivity within a carbon cage? 2022 Ingår i: Physical Chemistry Chemical Physics. - : Royal Society of Chemistry (RSC). - 1463-9076 .- 1463-9084. ; 24:47, s. 28994-29003 Tidskriftsartikel (refereegranskat)abstract We investigate the fragmentation dynamics of adamantane dications produced after core-ionization at the carbon edge followed by Auger decay. The combination of high-resolution electron spectroscopy, energy-resolved electron-ion multi-coincidence spectroscopy and different theoretical models allows us to give a complete characterization of the processes involved after ionization. We show that energy- and site-sensitivity is observed even for a highly-symmetric molecule that lacks any unique atomic site.
17.	Garg, D., et al. (författare) Fragmentation Dynamics of Fluorene Explored Using Ultrafast XUV-Vis Pump-Probe Spectroscopy 2022 Ingår i: Frontiers in Physics. - : Frontiers Media SA. - 2296-424X. ; 10 Tidskriftsartikel (refereegranskat)abstract We report on the use of extreme ultraviolet (XUV, 30.3 nm) radiation from the Free-electron LASer in Hamburg (FLASH) and visible (Vis, 405 nm) photons from an optical laser to investigate the relaxation and fragmentation dynamics of fluorene ions. The ultrashort laser pulses allow to resolve the molecular processes occurring on the femtosecond timescales. Fluorene is a prototypical small polycyclic aromatic hydrocarbon (PAH). Through their infrared emission signature, PAHs have been shown to be ubiquitous in the universe, and they are assumed to play an important role in the chemistry of the interstellar medium. Our experiments track the ionization and dissociative ionization products of fluorene through time-of-flight mass spectrometry and velocity-map imaging. Multiple processes involved in the formation of each of the fragment ions are disentangled through analysis of the ion images. The relaxation lifetimes of the excited fluorene monocation and dication obtained through the fragment formation channels are reported to be in the range of a few tens of femtoseconds to a few picoseconds.
18.	Gryzlova, E. V., et al. (författare) Influence of an atomic resonance on the coherent control of the photoionization process 2022 Ingår i: Physical Review Research. - 2643-1564. ; 4:3 Tidskriftsartikel (refereegranskat)abstract In coherent control schemes, pathways connecting an initial and a final state can be independently controlled by manipulating the complex amplitudes of their transition matrix elements. For paths characterized by the absorption of multiple photons, these quantities depend on the magnitude and phase between the intermediate steps, and are expected to be strongly affected by the presence of resonances. We investigate the coherent control of the photoemission process in neon using a phase-controlled two-color extreme ultraviolet pulse with frequency in proximity of an excited energy state. Using helium as a reference, we show that the presence of such a resonance in neon modifies the amplitude and phase of the asymmetric emission of photoelectrons. Theoretical simulations based on perturbation theory are in fair agreement with the experimental observations.
19.	Iablonskyi, D., et al. (författare) Interatomic Coulombic Decay Processes after Multiple Valence Excitations in Ne Clusters 2015 Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6596 .- 1742-6588. ; 635, s. 112067-112067 Konferensbidrag (refereegranskat)abstract We present a comprehensive analysis of autoionization processes in Ne clusters (similar to 5000 atoms) after multiple valence excitations by free electron laser radiation. The evolution from 2-body interatomic Coulombic decay (ICD) to 3-body ICD is demonstrated when changing from surface to bulk Frenkel exciton excitation. Super Coster-Kronig type 2-body ICD is observed at Wannier exciton which quenches the main ICD channel.
20.	Ilchen, M., et al. (författare) X-ray spectroscopy on ultrafast-decaying core-excited atomic ions 2020 Ingår i: Charge-exchange. - : IOP Publishing. - 1742-6588. ; 1412 Konferensbidrag (refereegranskat)abstract Results from the first soft X-ray user experiment at the European XFEL on nonlinear photon-matter interaction will be presented. Angle-resolved electron time-of-flight spectroscopy employed at the AQS (Atomic- like Quantum Systems) endstation of the SQS (Small Quantum Systems) instrument reveals insight into the character of resonances in highly transient, core ionized neon ions, i.e. Ne:+ 1s12s22p6 → Ne+&∗ 1s02s22p6np, together with their respective relaxation dynamics. Enabled by the unique properties of the European XFEL, novel perspectives on efficient nonlinear spectroscopy will be discussed.
21.	Kovács, K, et al. (författare) Multi-parameter optimization of a loose focusing high flux high-harmonic beamline 2019 Ingår i: Journal of Physics B: Atomic, Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 52:5, s. 055402-055402 Tidskriftsartikel (refereegranskat)abstract We perform a multi-dimensional parameter scan in the generation of high-order harmonics, with the main purpose to find the macroscopic conditions that optimize the harmonic yield in a specific spectral domain, around 40 eV for this particular case. The scanned parameters are the laser pulse energy, gas pressure, interaction cell position relative to focus and the cell length, while the fixed parameters are chosen to model a loose focusing configuration which is used in many existing laboratories. We performed the simulations with a 3D non-adiabatic model complemented by a detailed analysis of the phase matching mechanisms involved in an efficient harmonic generation. Based on the results we identify a range of parameter combinations that lead to a high yield in the specified spectral domain. The method and results presented here can be the framework for the design and construction of high flux high-order harmonic generation beamlines.
22.	Lee, J. W.L., et al. (författare) Time-resolved relaxation and fragmentation of polycyclic aromatic hydrocarbons investigated in the ultrafast XUV-IR regime 2021 Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 12:1 Tidskriftsartikel (refereegranskat)abstract Polycyclic aromatic hydrocarbons (PAHs) play an important role in interstellar chemistry and are subject to high energy photons that can induce excitation, ionization, and fragmentation. Previous studies have demonstrated electronic relaxation of parent PAH monocations over 10-100 femtoseconds as a result of beyond-Born-Oppenheimer coupling between the electronic and nuclear dynamics. Here, we investigate three PAH molecules: fluorene, phenanthrene, and pyrene, using ultrafast XUV and IR laser pulses. Simultaneous measurements of the ion yields, ion momenta, and electron momenta as a function of laser pulse delay allow a detailed insight into the various molecular processes. We report relaxation times for the electronically excited PAH, PAH(+) and PAH(2+*) states, and show the time-dependent conversion between fragmentation pathways. Additionally, using recoil-frame covariance analysis between ion images, we demonstrate that the dissociation of the PAH(2+) ions favors reaction pathways involving two-body breakup and/or loss of neutral fragments totaling an even number of carbon atoms. Polycyclic aromatic hydrocarbons play an important role in interstellar chemistry, where interaction with high energy photons can induce ionization and fragmentation reactions. Here the authors, with XUV-IR pump-probe experiments, investigate the ultrafast photoinduced dynamics of fluorene, phenanthrene and pyrene, providing insight into their preferred reaction channels.
23.	Maclot, Sylvain, et al. (författare) Photodissociation dynamics of the diamondoid adamantane induced by attosecond XUV pulses 2020 Ingår i: 31st international conference on photonic, electronic and atomic collisions (icpeac xxxi). - : IOP Publishing. ; 1412 Konferensbidrag (refereegranskat)abstract Adamantane is the simplest of the diamondoid molecules, which due to their high stability are of high interest both in astrophysics and nanotechnology. This work investigates the molecular photodissociation after ionization by attosecond XUV pulses. The fragmentation dynamics is inferred by means of velocity map imaging spectrometry, covariance analysis techniques and quantum chemistry calculations.
24.	Manschwetus, B., et al. (författare) Ultrafast ionization and fragmentation dynamics of polycyclic atomatic hydro-carbons by XUV radiation 2020 Ingår i: Free Electron Laser. - : IOP Publishing. - 1742-6588. ; 1412 Konferensbidrag (refereegranskat)abstract In the interstellar medium polycyclic aromatic hydrocarbon molecules (PAH) are exposed to strong ionizing radation leading to complex organic photochemistry. We investigated these ultrafast fragmentation reac-tions after ionization of the PAHs phenanthrene, fluorene and pyrene at a wavelength of 30.3 nm using pump probe spectroscopy at a free electron laser. We observe double ionization and afterwards hydrogen abstraction and acetylene loss with characteristic time scales for the reaction processes below one hundred femtoseconds.
25.	Mazza, T., et al. (författare) Mapping Resonance Structures in Transient Core-Ionized Atoms 2020 Ingår i: Physical Review X. - 2160-3308. ; 10:4 Tidskriftsartikel (refereegranskat)abstract The nature of transient electronic states created by photoabsorption critically determines the dynamics of the subsequently evolving system. Here, we investigate K-shell photoionized atomic neon by absorbing a second photon within the Auger-decay lifetime of 2.4 fs using the European XFEL, a unique high-repetition-rate, wavelength-tunable x-ray free-electron laser. By high-resolution electron spectroscopy, we map out the transient Rydberg resonances unraveling the details of the subsequent decay of the hollow atom. So far, ultra-short-lived electronic transients, which are often inaccessible by experiments, were mainly inferred from theory but are now addressed by nonlinear x-ray absorption. The successful characterization of these resonances with femtosecond lifetimes provides the basis for a novel class of site-specific, nonlinear, and time-resolved studies with strong impact for a wide range of topics in physics and chemistry.
26.	Wabnitz, H., et al. (författare) Generation of attosecond pulses in molecular nitrogen 2006 Ingår i: European Physical Journal D. Atomic, Molecular, Optical and Plasma Physics. - : Springer Science and Business Media LLC. - 1434-6060. ; 40:2, s. 305-311 Tidskriftsartikel (refereegranskat)abstract We have generated attosecond pulse trains in an ensemble of randomly aligned nitrogen molecules. Measurements of the high-order harmonic relative phases and amplitudes allow us to reconstruct the temporal profile of the attosecond pulses. We show that in the considered spectral range, the latter is very similar to the pulse train generated in argon under the same conditions. We discuss the possible influence of the molecular structure in the generation process, and how it can induce subtle differences on the relative phases.
27.	Zettergren, Henning, et al. (författare) Roadmap on dynamics of molecules and clusters in the gas phase 2021 Ingår i: European Physical Journal D. - : Springer Science and Business Media LLC. - 1434-6060 .- 1434-6079. ; 75:5 Tidskriftsartikel (refereegranskat)abstract This roadmap article highlights recent advances, challenges and future prospects in studies of the dynamics of molecules and clusters in the gas phase. It comprises nineteen contributions by scientists with leading expertise in complementary experimental and theoretical techniques to probe the dynamics on timescales spanning twenty order of magnitudes, from attoseconds to minutes and beyond, and for systems ranging in complexity from the smallest (diatomic) molecules to clusters and nanoparticles. Combining some of these techniques opens up new avenues to unravel hitherto unexplored reaction pathways and mechanisms, and to establish their significance in, e.g. radiotherapy and radiation damage on the nanoscale, astrophysics, astrochemistry and atmospheric science.
28.	Andersson, Peder, et al. (författare) Predicting neurological outcome after out-of-hospital cardiac arrest with cumulative information; development and internal validation of an artificial neural network algorithm 2021 Ingår i: Critical Care. - : Springer Science and Business Media LLC. - 1364-8535. ; 25:1 Tidskriftsartikel (refereegranskat)abstract BackgroundPrognostication of neurological outcome in patients who remain comatose after cardiac arrest resuscitation is complex. Clinical variables, as well as biomarkers of brain injury, cardiac injury, and systemic inflammation, all yield some prognostic value. We hypothesised that cumulative information obtained during the first three days of intensive care could produce a reliable model for predicting neurological outcome following out-of-hospital cardiac arrest (OHCA) using artificial neural network (ANN) with and without biomarkers.MethodsWe performed a post hoc analysis of 932 patients from the Target Temperature Management trial. We focused on comatose patients at 24, 48, and 72 h post-cardiac arrest and excluded patients who were awake or deceased at these time points. 80% of the patients were allocated for model development (training set) and 20% for internal validation (test set). To investigate the prognostic potential of different levels of biomarkers (clinically available and research-grade), patients' background information, and intensive care observation and treatment, we created three models for each time point: (1) clinical variables, (2) adding clinically accessible biomarkers, e.g., neuron-specific enolase (NSE) and (3) adding research-grade biomarkers, e.g., neurofilament light (NFL). Patient outcome was the dichotomised Cerebral Performance Category (CPC) at six months; a good outcome was defined as CPC 1-2 whilst a poor outcome was defined as CPC 3-5. The area under the receiver operating characteristic curve (AUROC) was calculated for all test sets.ResultsAUROC remained below 90% when using only clinical variables throughout the first three days in the ICU. Adding clinically accessible biomarkers such as NSE, AUROC increased from 82 to 94% (p<0.01). The prognostic accuracy remained excellent from day 1 to day 3 with an AUROC at approximately 95% when adding research-grade biomarkers. The models which included NSE after 72 h and NFL on any of the three days had a low risk of false-positive predictions while retaining a low number of false-negative predictions.ConclusionsIn this exploratory study, ANNs provided good to excellent prognostic accuracy in predicting neurological outcome in comatose patients post OHCA. The models which included NSE after 72 h and NFL on all days showed promising prognostic performance.
29.	Björkholm, P., et al. (författare) Navigation in vehicle crash test using MEMS-based IMU 2010 Ingår i: IEEE PLANS, Position Location and Navigation Symposium. - 9781424450367 ; , s. 27-31 Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract Results from our experiments on inertial navigation in crash testing of vehicles are presented. A custom designed inertial measurement unit (IMU) has been developed, and several tests in dummy calibration rigs including full-scale Euro NCAP collisions have been performed at our partners' crash test laboratories. For reference, the IMU data is compared to camera data and traditional single-axis inertial sensors. ©2010 IEEE.
30.	Bose, R, et al. (författare) Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors 2015 Ingår i: Cell death & disease. - : Springer Science and Business Media LLC. - 2041-4889. ; 6, s. e1793- Tidskriftsartikel (refereegranskat)abstract Developmental exposure to excess glucocorticoids (GCs) has harmful neurodevelopmental effects, which include persistent alterations in the differentiation potential of embryonic neural stem cells (NSCs). The mechanisms, however, are largely unknown. Here, we investigated the effects of dexamethasone (Dex, a synthetic GC analog) by MeDIP-like genome-wide analysis of differentially methylated DNA regions (DMRs) in NSCs isolated from embryonic rat cortices. We found that Dex-induced genome-wide DNA hypomethylation in the NSCs in vitro. Similarly, in utero exposure to Dex resulted in global DNA hypomethylation in the cerebral cortex of 3-day-old mouse pups. Dex-exposed NSCs displayed stable changes in the expression of the DNA methyltransferase Dnmt3a, and Dkk1, an essential factor for neuronal differentiation. These alterations were dependent on Tet3 upregulation. In conclusion, we propose that GCs elicit strong and persistent effects on DNA methylation in NSCs with Tet3 playing an essential role in the regulation of Dnmt3a and Dkk1. Noteworthy is the occurrence of similar changes in Dnmt3a and Dkk1 gene expression after exposure to excess GC in vivo.
31.	Cadwell, CR, et al. (författare) Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex 2020 Ingår i: eLife. - 2050-084X. ; 9 Tidskriftsartikel (refereegranskat)
32.	Campi, F., et al. (författare) The high intensity HHG beamline at lund laser 2014 Ingår i: High Intensity Lasers and High Field Phenomena, HILAS 2014. - 9781557529954 Konferensbidrag (refereegranskat)abstract We will present the new Lund HHG beamline designed for high photon flux, delivering pulse energies of more than 4 μJ per pulse in the spectral range from 20 eV to 45 eV. Focused XUV intensities above 1014 W/cm2 should become possible.
33.	Coudert-Alteirac, H., et al. (författare) The high-intensity HHG beamline at the lund laser centre : Towards XUV-pump XUV-probe experiments 2019 Ingår i: Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015. - 9781467374750 Konferensbidrag (refereegranskat)
34.	Curbis, F, et al. (författare) HIGHLIGHTS FROM THE CONCEPTUAL DESIGN REPORT OF THE SOFT X-RAY LASER AT MAX IV 2021 Ingår i: Proceedings of IPAC2021. Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract The SXL (Soft X-ray Laser) project developed a conceptual design for a soft X-ray Free Electron Laser (FEL) in the 1-5 nm wavelength range, driven by the existing MAX IV 3 GeV linac. In this contribution we will focus on the FEL operation modes developed for the first phase of the project based on two different linac modes. The design work was supported by the Knut and Alice Wallenberg foundation and by several Swedish universities and organizations (
35.	Ederth, J., Johnsson, P., Niklasson, G.A., Hoel, A., Hultåker, A., Heszler, P., Granqvist, C.G., van Doorn, A.R., Jongerius, M.J., Burgard, D. (författare) Electrical and optical properties of thin films consisting of tin-doped indium oxide nanoparticles 2003 Ingår i: Physical Review B (Condensed Matter and Materials Physics) 68, 155410, (1-10) (2003).. Tidskriftsartikel (refereegranskat)
36.	Floerchinger, A, et al. (författare) Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging 2021 Ingår i: Cell reports. - : Elsevier BV. - 2211-1247. ; 36:11, s. 109689- Tidskriftsartikel (refereegranskat)
37.	Haugen, H.A., et al. (författare) Infrastructure for CCS in the Skagerrak/Kattegat region, Southern Scandinavia: A feasibility study 2013 Ingår i: Energy Procedia. - : Elsevier BV. - 1876-6102. ; 37, s. 2562-2569 Konferensbidrag (refereegranskat)abstract This paper gives an overview of results from a project which explored the feasibility of establishing a CO2 Capture and Storage infrastructure in the Skagerrak/Kattegat region of Southern Scandinavia. This involves assessment of the technical and economic parameters of the complete CCS chain and, in particular, identification of possible storage locations. The project ran from June 2009 to December 2011. Emissions from three major industrial clusters in the Skagerrak/Kattegat region - Gothenburg in Sweden, Grenland in Telemark County, southern Norway and Aalborg in Denmark - were targeted. Both emissions from process industries as well as power plants were included.
38.	Heyl, C. M., et al. (författare) High-average power high-harmonic and attosecond sources : Status and prospects 2016 Ingår i: Compact EUV and X-ray Light Sources, EUVXRAY 2016. - 9781943580095 ; Part F14-EUVXRAY 2016 Konferensbidrag (refereegranskat)abstract Experiments employing extreme ultraviolet sources based on high harmonic generation often suffer from photon flux limitations. We discuss current status and prospects for scaling such sources to higher repetition rate, pulse energy and average power.
39.	Heyl, C. M., et al. (författare) Noncollinear optical gating - A method for intra-cavity single attosecond pulse generation? 2019 Ingår i: Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015. - 9781467374750 Konferensbidrag (refereegranskat)abstract The process of high-order harmonic generation requires laser intensities around 1014 W/cm2, most easily reached with laser pulses of high energy, thus implicitly limiting the repetition rate of attosecond sources. A route towards multi-MHz attosecond sources relies on HHG inside a passive enhancement cavity [1]. Although successfully demonstrated for attosecond pulse trains, the generation of single attosecond pulses (SAPs) inside a cavity remains an unsolved challenge, mainly limited by dispersion management and out-coupling problems. We recently proposed a new gating concept for SAP generation [2], noncollinear optical gating (NOG) which has the potential to facilitate SAP gating and efficient out-coupling at once. Similar to the recently introduced attosecond lighthouse [3] NOG employs attosecond angular streaking [4] and combines this concept with noncollinear HHG, proposed earlier [5] as out-coupling method for intra cavity HHG.
40.	Heyl, C. M., et al. (författare) Power-scaling attosecond sources using universal scaling principles for nonlinear optical processes in gases 2016 Ingår i: Laser Science, LS 2016. - 9781943580194 Konferensbidrag (refereegranskat)abstract Scaling attosecond sources to higher pulse energy and/or repetition rate can benefit many applications. We present a scaling framework for nonlinear light-matter interactions, applicable to attosecond pulse generation and other nonlinear phenomena as e.g. filamentation.
41.	Jarnac, A., et al. (författare) Generation of energetic compressed laser pulses in a planar hollow waveguide for high-order harmonic generation 2019 Ingår i: Proceedings 2015 European Conference on Lasers and Electro-Optics - European Quantum Electronics Conference, CLEO/Europe-EQEC 2015. - 9781467374750 Konferensbidrag (refereegranskat)abstract We present post-compression of a TW class laser in a planar hollow waveguide. The viability of the compressed pulses for applications in strong-field physics is demonstrated by generating high-order harmonics in a gas jet.
42.	Johnsson, Per, et al. (författare) Attosecond electron wave packet dynamics in strong laser fields 2005 Ingår i: Physical Review Letters. - 1079-7114. ; 95:1, s. 1-013001 Tidskriftsartikel (refereegranskat)abstract We use a train of sub-200 attosecond extreme ultraviolet (XUV) pulses with energies just above the ionization threshold in argon to create a train of temporally localized electron wave packets. We study the energy transfer from a strong infrared (IR) laser field to the ionized electrons as a function of the delay between the XUV and IR fields. When the wave packets are born at the zero crossings of the IR field, a significant amount of energy (similar to 20 eV) is transferred from the field to the electrons. This results in dramatically enhanced above-threshold ionization in conditions where the IR field alone does not induce any significant ionization. Because both the energy and duration of the wave packets can be varied independently of the IR laser, they are valuable tools for studying and controlling strong-field processes.
43.	Kilpinen, P., et al. (författare) Investigation of N2O reduction processes in circulating fluidised bed combustion chambers 1999 Ingår i: Technologies and combustion for a clean environment. Bokkapitel (övrigt vetenskapligt/konstnärligt)
44.	Kolosenko, I, et al. (författare) Spontaneous time-dependent accumulation of interferon-regulatory factor 9 induces chemo-resistance in colon carcinoma cells independently of STAT1 signaling 2013 Ingår i: CANCER RESEARCH. - 0008-5472. ; 73:8 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
45.	Kornilov, O., et al. (författare) Coulomb explosion of diatomic molecules in intense XUV fields mapped by partial covariance 2013 Ingår i: Journal of Physics B: Atomic, Molecular and Optical Physics. - : IOP Publishing. - 0953-4075 .- 1361-6455. ; 46:16 Tidskriftsartikel (refereegranskat)abstract Single-shot time-of-flight spectra for Coulomb explosion of N-2 and I-2 molecules have been recorded at the Free Electron LASer in Hamburg (FLASH) and have been analysed using a partial covariance mapping technique. The partial covariance analysis unravels a detailed picture of all significant Coulomb explosion pathways, extending up to the N4+-N5+ channel for nitrogen and up to the I8+-I9+ channel for iodine. The observation of the latter channel is unexpected if only sequential ionization processes from the ground state ions are considered. The maximum kinetic energy release extracted from the covariance maps for each dissociation channel shows that Coulomb explosion of nitrogen molecules proceeds much faster than that of the iodine. The N-2 ionization dynamics is modelled using classical trajectory simulations in good agreement with the outcome of the experiments. The results suggest that covariance mapping of the Coulomb explosion can be used to measure the intensity and pulse duration of free-electron lasers.
46.	Lee, J. W. L., et al. (författare) The kinetic energy of PAH dication and trication dissociation determined by recoil-frame covariance map imaging 2022 Ingår i: Physical Chemistry, Chemical Physics - PCCP. - : Royal Society of Chemistry (RSC). - 1463-9076 .- 1463-9084. ; 24:38, s. 23096-23105 Tidskriftsartikel (refereegranskat)abstract We investigated the dissociation of dications and trications of three polycyclic aromatic hydrocarbons (PAHs), fluorene, phenanthrene, and pyrene. PAHs are a family of molecules ubiquitous in space and involved in much of the chemistry of the interstellar medium. In our experiments, ions are formed by interaction with 30.3 nm extreme ultraviolet (XUV) photons, and their velocity map images are recorded using a PImMS2 multi-mass imaging sensor. Application of recoil-frame covariance analysis allows the total kinetic energy release (TKER) associated with multiple fragmentation channels to be determined to high precision, ranging 1.94-2.60 eV and 2.95-5.29 eV for the dications and trications, respectively. Experimental measurements are supported by Born-Oppenheimer molecular dynamics (BOMD) simulations.
47.	Li, Shuiqing, et al. (författare) The 8th International Symposium on Coal Combustion (ISCC-8) 2016 Ingår i: Fuel. - : Elsevier BV. - 0016-2361. ; 184, s. 873- Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
48.	Major, B., et al. (författare) Macroscopic Optimization of High Harmonic Generation for High Power Laser Pulses 2016 Ingår i: High Intensity Lasers and High Field Phenomena, HILAS 2016. - 9781943580095 ; Part F15-HILAS 2016 Konferensbidrag (refereegranskat)abstract We study upscaling of gas high harmonic generation, to make efficient use of the ever increasing laser pulse powers. Loose focusing geometries optimizing phasematching are investigated and compared in HHG efficiency to shorter focusing arrangements.
49.	Makos, I, et al. (författare) Α 10-gigawatt attosecond source for non-linear XUV optics and XUV-pump-XUV-probe studies 2020 Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 10:1 Tidskriftsartikel (refereegranskat)abstract The quantum mechanical motion of electrons and nuclei in systems spatially confined to the molecular dimensions occurs on the sub-femtosecond to the femtosecond timescales respectively. Consequently, the study of ultrafast electronic and, in specific cases, nuclear dynamics requires the availability of light pulses with attosecond (asec) duration and of sufficient intensity to induce two-photon processes, essential for probing the intrinsic system dynamics. The majority of atoms, molecules and solids absorb in the extreme-ultraviolet (XUV) spectral region, in which the synthesis of the required attosecond pulses is feasible. Therefore, the XUV spectral region optimally serves the study of such ultrafast phenomena. Here, we present a detailed review of the first 10-GW class XUV attosecond source based on laser driven high harmonic generation in rare gases. The pulse energy of this source largely exceeds other laser driven attosecond sources and is comparable to the pulse energy of femtosecond Free-Electron-Laser (FEL) XUV sources. The measured pulse duration in the attosecond pulse train is 650 ± 80 asec. The uniqueness of the combined high intensity and short pulse duration of the source is evidenced in non-linear XUV-optics experiments. It further advances the implementation of XUV-pump-XUV-probe experiments and enables the investigation of strong field effects in the XUV spectral region.
50.	Manschwetus, B., et al. (författare) Two-photon double ionization of neon studied with intense attosecond pulse trains 2016 Ingår i: International Conference on Ultrafast Phenomena, UP 2016. - 9781943580187 ; Part F20-UP 2016 Konferensbidrag (refereegranskat)abstract We focused an intense attosecond pulse train into a neon gas target and observed Ne2+ resulting from two-photon double ionization. By modifying the photon spectrum we find that the process is dominated by the sequential ionization via the Ne+ ion.

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