| 1. |
|
|
| 2. |
- Reifarth, R., et al.
(författare)
-
Nuclear astrophysics with radioactive ions at FAIR
- 2016
-
Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 665:1
-
Konferensbidrag (refereegranskat)abstract
- The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process beta-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes.
|
|
| 3. |
- Heine, M., et al.
(författare)
-
Determination of the neutron-capture rate of C-17 for r-process nucleosynthesis
- 2017
-
Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 95:1, s. Article no 014613 -
-
Tidskriftsartikel (refereegranskat)abstract
- With the (RB)-B-3-LAND setup at GSI we have measured exclusive relative-energy spectra of the Coulomb dissociation of C-18 at a projectile energy around 425A MeV on a lead target, which are needed to determine the radiative neutron-capture cross sections of C-17 into the ground state of C-18. Those data have been used to constrain theoretical calculations for transitions populating excited states in C-18. This allowed to derive the astrophysical cross section sigma(n gamma)*. accounting for the thermal population of C-17 target states in astrophysical scenarios. The experimentally verified capture rate is significantly lower than those of previously obtained Hauser-Feshbach estimations at temperatures T-9
|
|
| 4. |
- Röder, M., et al.
(författare)
-
Coulomb dissociation of 20,21 N
- 2016
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 93:6
-
Tidskriftsartikel (refereegranskat)abstract
- Neutron-rich light nuclei and their reactions play an important role in the creation of chemical elements. Here, data from a Coulomb dissociation experiment on N20,21 are reported. Relativistic N20,21 ions impinged on a lead target and the Coulomb dissociation cross section was determined in a kinematically complete experiment. Using the detailed balance theorem, the N19(n,γ)N20 and N20(n,γ)N21 excitation functions and thermonuclear reaction rates have been determined. The N19(n,γ)N20 rate is up to a factor of 5 higher at T
|
|
| 5. |
- Thies, Ronja, 1987, et al.
(författare)
-
Systematic investigation of projectile fragmentation using beams of unstable B and C isotopes
- 2016
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 93:5
-
Tidskriftsartikel (refereegranskat)abstract
- Models describing nuclear fragmentation and fragmentation fission deliver important input for planning nuclear physics experiments and future radioactive ion beam facilities. These models are usually benchmarked against data from stable beam experiments. In the future, two-step fragmentation reactions with exotic nuclei as stepping stones are a promising tool for reaching the most neutron-rich nuclei, creating a need for models to describe also these reactions. Purpose: We want to extend the presently available data on fragmentation reactions towards the light exotic region on the nuclear chart. Furthermore, we want to improve the understanding of projectile fragmentation especially for unstable isotopes. Method: We have measured projectile fragments from C10,12-18 and B10-15 isotopes colliding with a carbon target. These measurements were all performed within one experiment, which gives rise to a very consistent data set. We compare our data to model calculations. Results: One-proton removal cross sections with different final neutron numbers (1pxn) for relativistic C10,12-18 and B10-15 isotopes impinging on a carbon target. Comparing model calculations to the data, we find that the epax code is not able to describe the data satisfactorily. Using abrabla07 on the other hand, we find that the average excitation energy per abraded nucleon needs to be decreased from 27 MeV to 8.1 MeV. With that decrease abrabla07 describes the data surprisingly well. Conclusions: Extending the available data towards light unstable nuclei with a consistent set of new data has allowed a systematic investigation of the role of the excitation energy induced in projectile fragmentation. Most striking is the apparent mass dependence of the average excitation energy per abraded nucleon. Nevertheless, this parameter, which has been related to final-state interactions, requires further study.
|
|
| 6. |
- Altstadt, S.G., et al.
(författare)
-
B-13,B-14(n,gamma) via Coulomb Dissociation for Nucleosynthesis towards the r-Process
- 2014
-
Ingår i: Nuclear Data Sheets. - : Elsevier BV. - 1095-9904 .- 0090-3752. ; 120, s. 197-200
-
Konferensbidrag (refereegranskat)abstract
- Radioactive beams of 14,15B produced by fragmentation of a primary 40Ar beam were directed onto a Pb target to investigate the neutron breakup within the Coulomb field. The experiment was performed at the LAND/R3B setup. Preliminary results for the Coulomb dissociation cross sections as well as for the astrophysically interesting inverse reactions, 13,14B(n,γ), are presented.
|
|
| 7. |
- Caesar, C., et al.
(författare)
-
Beyond the neutron drip line: The unbound oxygen isotopes O-25 and O-26
- 2013
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813. ; 88:3
-
Tidskriftsartikel (refereegranskat)abstract
- The very neutron-rich oxygen isotopes O-25 and O-26 are investigated experimentally and theoretically. The unbound states are populated in an experiment performed at the R3B-LAND setup at GSI via proton-knockout reactions from F-26 and F-27 at relativistic energies around 442 and 414 MeV/nucleon, respectively. From the kinematically complete measurement of the decay into O-24 plus one or two neutrons, the O-25 ground-state energy and width are determined, and upper limits for the O-26 ground-state energy and lifetime are extracted. In addition, the results provide indications for an excited state in O-26 at around 4 MeV. The experimental findings are compared to theoretical shell-model calculations based on chiral two- and three-nucleon (3N) forces, including for the first time residual 3N forces, which are shown to be amplified as valence neutrons are added.
|
|
| 8. |
- Vandebrouck, M., et al.
(författare)
-
Effective proton-neutron interaction near the drip line from unbound states in F-25,F-26
- 2017
-
Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 96:5
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Odd-odd nuclei, around doubly closed shells, have been extensively used to study proton-neutron interactions. However, the evolution of these interactions as a function of the binding energy, ultimately when nuclei become unbound, is poorly known. The F-26 nucleus, composed of a deeply bound pi 0d(5/2) proton and an unbound v0d(3/2) neutron on top of an O-24 core, is particularly adapted for this purpose. The coupling of this proton and neutron results in a J(pi) = 1(1)(+) - 4(1)(+) multiplet, whose energies must be determined to study the influence of the proximity of the continuum on the corresponding proton-neutron interaction. The J(pi) = 1(1)(+), 2(1)(+), 4(1)(+) bound states have been determined, and only a clear identification of the J(pi) = 3(1)(+) is missing. Purpose: We wish to complete the study of the J(pi) = 1(1)(+) - 4(1)(+) multiplet in F-26, by studying the energy and width of the J(pi) = 3(1)(+) unbound state. The method was first validated by the study of unbound states in F-25, for which resonances were already observed in a previous experiment. Method: Radioactive beams of Ne-26 and Ne-27, produced at about 440AMeV by the fragment separator at the GSI facility were used to populate unbound states in F-25 and F-26 via one-proton knockout reactions on a CH2 target, located at the object focal point of the (RB)-B-3/LAND setup. The detection of emitted. rays and neutrons, added to the reconstruction of the momentum vector of the A - 1 nuclei, allowed the determination of the energy of three unbound states in F-25 and two in F-26. Results: Based on its width and decay properties, the first unbound state in F-25, at the relative energy of 49(9) keV, is proposed to be a J(pi) = 1/ 2(-) arising from a p1/2 proton- hole state. In F-26, the first resonance at 323(33) keV is proposed to be the J(pi) = 3(1)(+) member of the J(pi) = 1(1)(+) - 4(1)(+) multiplet. Energies of observed states in F-25,F-26 have been compared to calculations using the independent-particle shell model, a phenomenological shell model, and the ab initio valence-space in-medium similarity renormalization group method. Conclusions: The deduced effective proton- neutron interaction is weakened by about 30-40% in comparison to the models, pointing to the need for implementing the role of the continuum in theoretical descriptions or to a wrong determination of the atomic mass of F-26.
|
|
| 9. |
- Atar, L., et al.
(författare)
-
Quasifree (p, 2p) Reactions on Oxygen Isotopes: Observation of Isospin Independence of the Reduced Single-Particle Strength
- 2018
-
Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 120:5
-
Tidskriftsartikel (refereegranskat)abstract
- Quasifree one-proton knockout reactions have been employed in inverse kinematics for a systematic study of the structure of stable and exotic oxygen isotopes at the R3B/LAND setup with incident beam energies in the range of 300-450 MeV/u. The oxygen isotopic chain offers a large variation of separation energies that allows for a quantitative understanding of single-particle strength with changing isospin asymmetry. Quasifree knockout reactions provide a complementary approach to intermediate-energy one-nucleon removal reactions. Inclusive cross sections for quasifree knockout reactions of the type OA(p,2p)NA-1 have been determined and compared to calculations based on the eikonal reaction theory. The reduction factors for the single-particle strength with respect to the independent-particle model were obtained and compared to state-of-the-art ab initio predictions. The results do not show any significant dependence on proton-neutron asymmetry.
|
|
| 10. |
- Boillos, J. M., et al.
(författare)
-
Isotopic cross sections of fragmentation residues produced by light projectiles on carbon near
- 2022
-
Ingår i: Physical Review C. - 2469-9993 .- 2469-9985. ; 105:1
-
Tidskriftsartikel (refereegranskat)abstract
- We measured 135 cross sections of residual nuclei produced in fragmentation reactions of C12, N14, and O13−16,20,22 projectiles impinging on a carbon target at kinetic energies of near 400A MeV, most of them for the first time, with the RB3/LAND setup at the GSI facility in Darmstadt (Germany). The use of this state-of-the-art experimental setup in combination with the inverse kinematics technique gave the full identification in atomic and mass numbers of fragmentation residues with a high precision. The cross sections of these residues were determined with uncertainties below 20% for most of the cases. These data are compared to other previous measurements with stable isotopes and are also used to benchmark different model calculations.
|
|
| 11. |
- Diaz Fernandez, Paloma, 1983, et al.
(författare)
-
Quasifree (p, pN) scattering of light neutron-rich nuclei near N=14
- 2018
-
Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 97:2
-
Tidskriftsartikel (refereegranskat)abstract
- Background: For many years, quasifree scattering reactions in direct kinematics have been extensively used to study the structure of stable nuclei, demonstrating the potential of this approach. The (RB)-B-3 collaboration has performed a pilot experiment to study quasifree scattering reactions in inverse kinematics for a stable C-12 beam. The results from that experiment constitute the first quasifree scattering results in inverse and complete kinematics. This technique has lately been extended to exotic beams to investigate the evolution of shell structure, which has attracted much interest due to changes in shell structure if the number of protons or neutrons is varied. Purpose: In this work we investigate for the first time the quasifree scattering reactions (p, pn) and (p, 2p) simultaneously for the same projectile in inverse and complete kinematics for radioactive beams with the aim to study the evolution of single-particle properties from N = 14 to N = 15. Method: The structure of the projectiles O-23, O-22, and N-21 has been studied simultaneously via (p, pn) and (p, 2p) quasifree knockout reactions in complete inverse kinematics, allowing the investigation of proton and neutron structure at the same time. The experimental data were collected at the (RB)-B-3-LAND setup at GSI at beam energies of around 400 MeV/u. Two key observables have been studied to shed light on the structure of those nuclei: the inclusive cross sections and the corresponding momentum distributions. Conclusions: The knockout reactions (p, pn) and (p, 2p) with radioactive beams in inverse kinematics have provided important and complementary information for the study of shell evolution and structure. For the (p, pn) channels, indications of a change in the structure of these nuclei moving from N = 14 to N = 15 have been observed, i.e., from the 0d(5/2) shell to the 1s(1/2). This supports previous observations of a subshell closure at N = 14 for neutron-rich oxygen isotopes and its weakening for the nitrogen isotopes.
|
|
| 12. |
- Revel, A., et al.
(författare)
-
Strong Neutron Pairing in core+4n Nuclei
- 2018
-
Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 120:15
-
Tidskriftsartikel (refereegranskat)abstract
- The emission of neutron pairs from the neutron-rich N=12 isotones C18 and O20 has been studied by high-energy nucleon knockout from N19 and O21 secondary beams, populating unbound states of the two isotones up to 15 MeV above their two-neutron emission thresholds. The analysis of triple fragment-n-n correlations shows that the decay N19(-1p)C18∗→C16+n+n is clearly dominated by direct pair emission. The two-neutron correlation strength, the largest ever observed, suggests the predominance of a C14 core surrounded by four valence neutrons arranged in strongly correlated pairs. On the other hand, a significant competition of a sequential branch is found in the decay O21(-1n)O20∗→O18+n+n, attributed to its formation through the knockout of a deeply bound neutron that breaks the O16 core and reduces the number of pairs.
|
|
| 13. |
- Ribeiro, G., et al.
(författare)
-
Structure of Be-13 studied in proton knockout from B-14
- 2018
-
Ingår i: Physical Review C. - 2469-9985 .- 2469-9993. ; 98:2
-
Tidskriftsartikel (refereegranskat)abstract
- The neutron-unbound isotope Be-13 has been studied in several experiments using different reactions, different projectile energies, and different experimental setups. There is, however, no real consensus in the interpretation of the data, in particular concerning the structure of the low-lying excited states. Gathering new experimental information, which may reveal the Be-13 structure, is a challenge, particularly in light of its bridging role between Be-12, where the N = 8 neutron shell breaks down, and the Borromean halo nucleus Be-14. The purpose of the present study is to investigate the role of bound excited states in the reaction product Be-12 after proton knockout from B-14, by measuring coincidences between Be-12, neutrons, and gamma rays originating from de-excitation of states fed by neutron decay of Be-13. The Be-13 isotopes were produced in proton knockout from a 400 MeV/nucleon B-14 beam impinging on a CH2 target. The Be-12-n relative-energy spectrum d sigma/dE(fn) was obtained from coincidences between Be-12(g.s.) and a neutron, and also as threefold coincidences by adding gamma rays, from the de-excitation of excited states in Be-12. Neutron decay from the first 5/2(+) state in Be-13 to the 2(+) state in Be-12 at 2.11 MeV is confirmed. An energy independence of the proton-knockout mechanism is found from a comparison with data taken with a 35 MeV/nucleon B-14 beam. A low-lying p-wave resonance in Be-13(1/2(-)) is confirmed by comparing proton- and neutron-knockout data from B-14 and Be-14.
|
|
| 14. |
- Tanaka, Y. K., et al.
(författare)
-
Search for eta '-mesic nuclei using (p,d) reaction with FRS/Super-FRS at GSI/FAIR
- 2020
-
Ingår i: Journal of Physics, Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 1643
-
Tidskriftsartikel (refereegranskat)abstract
- We plan a semi-exclusive measurement of the C-12(p,dp) reaction to search for eta'-mesic nuclei, aiming at investigating in-medium properties of the eta'-meson. We employ a 2.5 GeV proton beam impinging on a carbon target to produce eta'-mesic C-11 nuclei via the C-12(p,d)eta'circle times C-11 reaction. Using coincidence measurements of the forward going deuterons, important for missing-mass spectroscopy, and decay protons emitted from the eta'-mesic nuclei for event selection will provide a high experimental sensitivity to observe eta'-mesic nuclei. We will perform the measurements by combining the WASA detector system with the fragment separator FRS at GSI and also with the Super-FRS at FAIR in the future. The plan of the experiments and the present status are reported.
|
|
| 15. |
- Kanungo, R., et al.
(författare)
-
Exploring the anomaly in the interaction cross section and matter radius of 23O
- 2011
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813 .- 1089-490X. ; 84:6, s. art. no. 061304(R)-
-
Tidskriftsartikel (refereegranskat)abstract
- New measurements of the interaction cross sections of 22,23O at 900A MeV performed at the GSI, Darmstadt are reported that address the unsolved puzzle of the large cross section previously observed for 23O. The matter radii for these oxygen isotopes extracted through a Glauber model analysis are in good agreement with the new predictions of the ab initio coupled-cluster theory reported here. They are consistent with a 22O+neutron description of 23O as well.
|
|
| 16. |
- Kanungo, R., et al.
(författare)
-
Matter radii of 32-35Mg
- 2011
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993 .- 0556-2813 .- 1089-490X. ; 83:2
-
Tidskriftsartikel (refereegranskat)abstract
- The interaction cross sections of Mg32-35 at 900A MeV have been measurmed using the fragment separator at GSI. The deviation from the r(0)A(1/3) trend is slightly larger for Mg-35, signaling the possible formation of a longer tail in the neutron distribution for Mg-35. The radii extracted from a Glauber model analysis with Fermi densities are consistent with models predicting the development of neutron skins.
|
|
| 17. |
- Kanungo, R., et al.
(författare)
-
One-Neutron Removal Measurement Reveals O-24 as a New Doubly Magic Nucleus
- 2009
-
Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 102:15
-
Tidskriftsartikel (refereegranskat)abstract
- The first measurement of the momentum distribution for one-neutron removal from O-24 at 920A MeV performed at GSI, Darmstadt is reported. The observed distribution has a width (FWHM) of 99 +/- 4 MeV/c in the projectile rest frame and a one-neutron removal cross section of 63 +/- 7 mb. The results are well explained with a nearly pure 2s(1/2) neutron spectroscopic factor of 1.74 +/- 0.19 within the eikonal model. This large s-wave probability shows a spherical shell closure thereby confirming earlier suggestions that O-24 is a new doubly magic nucleus.
|
|
| 18. |
- Kanungo, R., et al.
(författare)
-
Structure of Mg-33 sheds new light on the N=20 island of inversion
- 2010
-
Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - Elsevier : Elsevier BV. - 0370-2693 .- 1873-2445. ; 685:4-5, s. 253-257
-
Tidskriftsartikel (refereegranskat)abstract
- The first reaction spectroscopy oil the ground state structure of Mg-33 through the measurement of the longitudinal momentum distribution from the one-neutron removal reaction Using a C target at 898A MeV is reported The experiment was performed at the FRS, GSI The distribution has a relatively narrow width (150 +/- 3 MeV/c (FWHM)) and the one-neutron removal cross-section is 74 +/- 4 mb An increased contribution from the (2)p(3/2) orbital is required to explain the observation showing its lowering compared to existing model predictions This provides new information regarding the configuration of Mg-33 and the island of inversion (C) 2010 Elsevier B V All rights reserved
|
|
| 19. |
- Nociforo, C., et al.
(författare)
-
One-neutron removal reactions on Al isotopes around the N=20 shell closure
- 2012
-
Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X .- 2469-9985 .- 2469-9993. ; 85:4, s. 044312-1-044312-10
-
Tidskriftsartikel (refereegranskat)abstract
- The one-neutron removal cross sections of neutron-rich Al isotopes and longitudinal momentum distributions of the residues have been measured for A=33 to 36 at relativistic energies (≈900 MeV/u). The inclusive data have been interpreted within the eikonal approximation. The evolution of the single-particle occupancy in the ground state of 33,34,35Al has been studied and compared with shell model predictions. The inferred 2s1/2 neutron occupancy in the 33Al ground-state wave function is 20% to 40% lower than the predicted one. The inclusive data do not exclude the presence of intruder states. Some intruder l=1 occupancy is found in 34Al, similarly to 33Mg. The single-particle 1f7/2 occupancy shows a gradual increase at N=22. Correspondingly, a decrease of the 1d3/2 strength has been observed.
|
|
| 20. |
- Nociforo, C., et al.
(författare)
-
Shell Closure N=16 in O-24
- 2009
-
Ingår i: AIP Conference Proceedings. - 1551-7616 .- 0094-243X. ; 1165, s. 90-93 461
-
Konferensbidrag (refereegranskat)abstract
- Advanced nuclear structure models predict the presence of the shell closures N=14, 16 in neutron-rich O isotopes rather than N=20. Spectroscopic investigations performed at the neutron drip line have recently confirmed such predictions showing that the O-24 is a doubly magic nucleus (Z=8, N=16). Predictions within the shell model calculation for the O-23,O-24 ground state have been confirmed measuring their spectroscopic factors. Results obtained in one-neutron removal reactions performed by using in-flight radioactive ion beams produced at the Fragment Separator FRS of GSI are reported.
|
|
| 21. |
- Syndikus, I., et al.
(författare)
-
Probing the Z = 6 spin-orbit shell gap with (p,2p) quasi-free scattering reactions
- 2020
-
Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 809
-
Tidskriftsartikel (refereegranskat)abstract
- The evolution of the traditional nuclear magic numbers away from the valley of stability is an active field of research. Experimental efforts focus on providing key spectroscopic information that will shed light into the structure of exotic nuclei and understanding the driving mechanism behind the shell evolution. In this work, we investigate the Z=6 spin-orbit shell gap towards the neutron dripline. To do so, we employed NA(p,2p)CA−1 quasi-free scattering reactions to measure the proton component of the 21+ state of 16,18,20C. The experimental findings support the notion of a moderate reduction of the proton 1p1/2−1p3/2 spin-orbit splitting, at variance to recent claims for a prevalent Z=6 magic number towards the neutron dripline.
|
|
| 22. |
- Vidal, R. M., et al.
(författare)
-
Colonization factors among enterotoxigenic Escherichia coli isolates from children with moderate-to-severe diarrhea and from matched controls in the Global Enteric Multicenter Study (GEMS)
- 2019
-
Ingår i: Plos Neglected Tropical Diseases. - : Public Library of Science (PLoS). - 1935-2735. ; 13:1
-
Tidskriftsartikel (refereegranskat)abstract
- Background Enterotoxigenic Escherichia coli (ETEC) encoding heat-stable enterotoxin (ST) alone or with heat-labile enterotoxin (LT) cause moderate-to-severe diarrhea (MSD) in developing country children. The Global Enteric Multicenter Study (GEMS) identified ETEC encoding ST among the top four enteropathogens. Since the GEMS objective was to provide evidence to guide development and implementation of enteric vaccines and other interventions to diminish diarrheal disease morbidity and mortality, we examined colonization factor (CF) prevalence among ETEC isolates from children age <5 years with MSD and from matched controls in four African and three Asian sites. We also assessed strength of association of specific CFs with MSD. Methodology/Principal findings MSD cases enrolled at healthcare facilities over three years and matched controls were tested in a standardized manner for many enteropathogens. To identify ETEC, three E. coli colonies per child were tested by polymerase chain reaction (PCR) to detect genes encoding LT, ST; confirmed ETEC were examined by PCR for major CFs (Colonization Factor Antigen I [CFA/I] or Coli Surface [CS] antigens CS1-CS6) and minor CFs (CS7, CS12, CS13, CS14, CS17, CS18, CS19, CS20, CS21, CS30). ETEC from 806 cases had a single toxin/CF profile in three tested strains per child. Major CFs, components of multiple ETEC vaccine candidates, were detected in 66.0% of LT/ST and ST-only cases and were associated with MSD versus matched controls by conditional logistic regression (p0.006); major CFs detected in only 25.0% of LT-only cases weren't associated with MSD. ETEC encoding exclusively CS14, identified among 19.9% of 291 ST-only and 1.5% of 259 LT/ST strains, were associated with MSD (p = 0.0011). No other minor CF exhibited prevalence 5% and significant association with MSD. Conclusions/Significance Major CF-based efficacious ETEC vaccines could potentially prevent up to 66% of pediatric MSD cases due to ST-encoding ETEC in developing countries; adding CS14 extends coverage to similar to 77%. Author summary Enterotoxigenic Escherichia coli (ETEC) were found to be one of the four most consistently important agents that cause moderate-to-severe diarrhea among children <5 years of age in a large case-control study, the Global Enteric Multicenter Study, performed in four countries in sub-Saharan Africa and three in South Asia. ETEC attach to the lining of the human small intestine by means of protein colonization factors (CFs), after which bacterial toxins stimulate intestinal secretion resulting in diarrhea. Moderate-to-severe diarrhea in young children in developing countries can lead to malnutrition and death. Vaccines are being developed to prevent ETEC diarrhea and its consequences. Several ETEC vaccines aim to stimulate antibodies (protective proteins) that will bind CFs and prevent the bacteria from attaching to intestinal cells, which should, in turn, prevent ETEC diarrhea. Different types of CFs exist. To guide the development of vaccines intending to provide broad protection against ETEC, one must know the frequency with which the different major CFs are produced by ETEC. This paper reports an extensive systematic survey of ETEC CFs and provides helpful information to guide the development of ETEC vaccines.
|
|
| 23. |
- Cortina-Gil, D., et al.
(författare)
-
One-neutron knockout of n-rich Ne isotopes at relativistic energies
- 2010
-
Ingår i: Nuclear Physics A. - : Elsevier BV. - 0375-9474. ; 834:1-4, s. 485C-487C
-
Konferensbidrag (refereegranskat)abstract
- Longitudinal fragment-momentum distributions resulting front one-neutron knockout of 40 different neutron-rich exotic species (Z ranging from 6-13) have been recently measured at high-energy (700 A MeV) using the FRS at GSI. This paper concentrates on results obtained for the Ne isotopic chain where five isotopes (Ne-24-Ne-28) have been Studied. The comparison of those experimental results with simple model calculations shows the evolution of the nuclear structure across neutron numbers N=14,16 in this transitional region in the neighbourhood of the island of inversion.
|
|
| 24. |
- Holl, M., et al.
(författare)
-
Quasi-free neutron and proton knockout reactions from light nuclei in a wide neutron-to-proton asymmetry range
- 2019
-
Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 795, s. 682-688
-
Tidskriftsartikel (refereegranskat)abstract
- The quasi-free scattering reactions 11C(p,2p) and 10,11,12C(p,pn) have been studied in inverse kinematics at beam energies of 300–400 MeV/u at the R3B-LAND setup. The outgoing proton-proton and proton-neutron pairs were detected in coincidence with the reaction fragments in kinematically complete measurements. The efficiency to detect these pairs has been obtained from GEANT4 simulations which were tested using the 12C(p,2p) and 12C(p,pn) reactions. Experimental cross sections and momentum distributions have been obtained and compared to DWIA calculations based on eikonal theory. The new results reported here are combined with previously published cross sections for quasi-free scattering from oxygen and nitrogen isotopes and together they enable a systematic study of the reduction of single-particle strength compared to predictions of the shell model over a wide neutron-to-proton asymmetry range. The combined reduction factors show a weak or no dependence on isospin asymmetry, in contrast to the strong dependency reported in nucleon-removal reactions induced by nuclear targets at lower energies. However, the reduction factors for (p,2p) are found to be 'significantly smaller than for (p,pn) reactions for all investigated nuclei.
|
|
| 25. |
- Maierbeck, P., et al.
(författare)
-
Probing the single particle structure around Ca-54 with one-neutron knock-out
- 2008
-
Ingår i: AIP Conference Proceedings. - 1551-7616 .- 0094-243X. ; 1012, s. 89-93
-
Konferensbidrag (refereegranskat)abstract
- The nuclei Ca-47 and Ti-55 were populated in one-neutron knock-out reactions at relativistic energies. Momentum distributions of the residual nuclei as well as gamma-ray spectra were measured at the GSI fragment separator (FRS). Preliminary results of the ongoing analysis including cross sections and spin/parity assignments are presented.
|
|
| 26. |
- Maierbeck, P., et al.
(författare)
-
Structure of 55Ti from relativistic one-neutron knockout
- 2009
-
Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693. ; 675:1, s. 22-27
-
Tidskriftsartikel (refereegranskat)abstract
- Results are presented from a one-neutron knockout reaction at relativistic energies on 56Ti using the GSI FRS as a two-stage magnetic spectrometer and the Miniball array for gamma-ray detection. Inclusive and exclusive longitudinal momentum distributions and cross-sections were measured enabling the determination of the orbital angular momentum of the populated states. First-time observation of the 955(6) keV -hole state in 55Ti is reported. The measured data for the first time proves that the ground state of 55Ti is a 1/2- state, in agreement with shell-model calculations using the GXPF1A interaction that predict a sizable N=34 gap in 54Ca.
|
|
| 27. |
- Rodriguez-Tajes, C., et al.
(författare)
-
Gamma-ray measurements in the one-neutron knockout of C-17, N-19, O-21 and F-25
- 2012
-
Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-601X .- 1434-6001. ; 48:7, s. Article Number: 95-95
-
Tidskriftsartikel (refereegranskat)abstract
- One-neutron knockout reactions in a 9 Be target have been investigated at relativistic energies, near 700 MeV/u, for a set of sd-shell, neutron-rich nuclei. The experiment was performed in the FRS spectrometer, at GSI. gamma-ray measurements were carried out by means of the MINIBALL gamma-ray spectrometer and allowed the determination of partial cross-sections and branching ratios corresponding to the final states of the emerging knockout fragments. Experimental results are presented for C-17, N-19, O-21 and F-25 projectiles. The role of excited states of the N - 1 fragments in the composition of the ground state of these neutron-rich projectiles is outlined in this work.
|
|
| 28. |
- Rodriguez-Tajes, C., et al.
(författare)
-
One-neutron knockout from light neutron-rich nuclei at relativistic energies
- 2010
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993. ; 82:2
-
Tidskriftsartikel (refereegranskat)abstract
- One-neutron knockout reactions from neutron-rich nuclei, with Z=6-13 and N=8-22, were studied at the Fragment Separator (GSI) at high beam energies, around 700 MeV/nucleon. Structural phenomena such as the formation of one-neutron halos in odd-mass carbon isotopes (15,17,19C) will be discussed. In addition, one-neutron knockout measurements from 22N were carried out for the first time and demonstrate clearly the change from a 0d5/2 to a 1s1/2 orbital for the valence neutron, an effect that is expected above N=14 and that was also observed in 23O and 24F. The possibility of an anomalous structure of 26F, due to a significant 1s1/2 neutron admixture, will also be discussed in the light of the experimental data obtained in this work. Finally, the ground-state configuration of neutron-rich neon isotopes (24-28Ne) was studied, providing new information in a region that is relatively close to the island of inversion.
|
|
| 29. |
- Rodriguez-Tajes, C., et al.
(författare)
-
One-neutron knockout from Ne24-28 isotopes
- 2010
-
Ingår i: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 687:1, s. 26-30
-
Tidskriftsartikel (refereegranskat)abstract
- One-neutron knockout reactions of Ne24-28 in a beryllium target have been studied in the Fragment Separator (FRS), at GSI. The results include inclusive one-neutron knockout cross-sections as well as longitudinal-momentum distributions of the knockout fragments. The ground-state structure of the neutron-rich neon isotopes was obtained from an analysis of the measured momentum distributions. The results indicate that the two heaviest isotopes, Ne-27 and Ne-28, are dominated by a configuration in which a s(1/2) neutron is coupled to an excited state of the Ne-26 and Ne-27 core, respectively. (C) 2010 Elsevier B.V. All rights reserved.
|
|
| 30. |
- Rodriguez-Tajes, C., et al.
(författare)
-
Structure of 22N and the N=14 subshell
- 2011
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993. ; 83:6
-
Tidskriftsartikel (refereegranskat)abstract
- One-neutron knockout data for N18-22 are analyzed in the eikonal approximation of the Glauber model. The role of the s-d shell and the crossing of the N = 14 neutron subshell are discussed. Of particular interest is the nucleus N-22, where the knockout data provide a sensitive experimental test for a possible halo structure of its ground state. The observation of a narrow momentum distribution of the N-21 fragments, together with an essential 1s(1/2) contribution needed to describe the observed longitudinal-momentum distribution, allow the firm conclusion that the ground state of N-22 is a well-developed nuclear halo. The results also show that the N = 14 subshell in N-22 is somewhat reduced as compared to that of O-23.
|
|
| 31. |
- Schwertel, S., et al.
(författare)
-
One-neutron knockout from Sc51-55
- 2012
-
Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-601X .- 1434-6001. ; 48:Dec., s. 191-10
-
Tidskriftsartikel (refereegranskat)abstract
- Results are presented from a one-neutron knockout experiment at relativistic energies of approximate to 420 A MeV on Sc51-55 using the GSI Fragment Separator as a two-stage magnetic spectrometer and the Miniball array for gamma-ray detection. Inclusive longitudinal momentum distributions and cross-sections were measured enabling the determination of the contributions corresponding to knockout from the nu p(1/2), nu p(3/2), (L = 1) and nu f(7/2), nu f(5/2) (L = 3) neutron orbitals. The observed L = 1 and L = 3 contributions are compared with theoretical cross-sections using eikonal knockout theory and spectroscopic factors from shell model calculations using the GXPF1A interaction. The measured inclusive knockout cross-sections generally follow the trends expected theoretically and given by the spectroscopic strength predicted from the shell model calculations. However, the deduced L = 1 cross-sections are generally 30-40% higher while the L = 3 contributions are about a factor of two smaller than predicted. This points to a promotion of neutrons from the nu f(7/2) to the nu p(3/2) orbital indicating a weakening of the N = 28 shell gap in these nuclei. While this is not predicted for the phenomenological GXPF1A interaction such a weakening is predicted by recent calculations using realistic low-momentum interactions V-lowk obtained by evolving a chiral N3LO nucleon-nucleon potential.
|
|
| 32. |
- Bhattacharya, S. K., et al.
(författare)
-
5 year efficacy of a bivalent killed whole-cell oral cholera vaccine in Kolkata, India: A cluster-randomised, double-blind, placebo-controlled trial
- 2013
-
Ingår i: Lancet. Infectious Diseases. - 1473-3099 .- 1474-4457. ; 13:12, s. 1050-1056
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Efficacy and safety of a two-dose regimen of bivalent killed whole-cell oral cholera vaccine (Shantha Biotechnics, Hyderabad, India) to 3 years is established, but long-term efficacy is not. We aimed to assess protective efficacy up to 5 years in a slum area of Kolkata, India. Methods: In our double-blind, cluster-randomised, placebo-controlled trial, we assessed incidence of cholera in non-pregnant individuals older than 1 year residing in 3933 dwellings (clusters) in Kolkata, India. We randomly allocated participants, by dwelling, to receive two oral doses of modified killed bivalent whole-cell cholera vaccine or heat-killed Escherichia coli K12 placebo, 14 days apart. Randomisation was done by use of a computer-generated sequence in blocks of four. The primary endpoint was prevention of episodes of culture-confirmed Vibrio cholerae O1 diarrhoea severe enough for patients to seek treatment in a health-care facility. We identified culture-confirmed cholera cases among participants seeking treatment for diarrhoea at a study clinic or government hospital between 14 days and 1825 days after receipt of the second dose. We assessed vaccine protection in a per-protocol population of participants who had completely ingested two doses of assigned study treatment. Findings: 69 of 31932 recipients of vaccine and 219 of 34968 recipients of placebo developed cholera during 5 year follow-up (incidence 2·2 per 1000 in the vaccine group and 6·3 per 1000 in the placebo group). Cumulative protective efficacy of the vaccine at 5 years was 65% (95% CI 52-74; p<0·0001), and point estimates by year of follow-up suggested no evidence of decline in protective efficacy. Interpretation: Sustained protection for 5 years at the level we reported has not been noted previously with other oral cholera vaccines. Established long-term efficacy of this vaccine could assist policy makers formulate rational vaccination strategies to reduce overall cholera burden in endemic settings. Funding: Bill & Melinda Gates Foundation and the governments of South Korea and Sweden. © 2013 Elsevier Ltd.
|
|
| 33. |
- Cubero, M., et al.
(författare)
-
Do Halo Nuclei Follow Rutherford Elastic Scattering at Energies Below the Barrier? The Case of 11Li
- 2012
-
Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 109:26
-
Tidskriftsartikel (refereegranskat)abstract
- The first measurement of the elastic scattering of the halo nucleus 11Li and its core 9Li on 208Pb at energies near the Coulomb barrier is presented. The 11Li+208Pb elastic scattering shows a strong reduction with respect to the Rutherford cross section, even at energies well below the barrier and down to very small scattering angles. This drastic change of the elastic differential cross section observed in 11Li+208Pb is the consequence of the halo structure of 11Li, as it is not observed in the elastic scattering of its core 9Li at the same energies. Four-body continuum-discretized coupled-channels calculations, based on a three-body model of the 11Li projectile, are found to explain the measured angular distributions and confirm that the observed reduction is mainly due to the strong Coulomb coupling to the dipole states in the low-lying continuum of 11Li. These calculations suggest the presence of a low-lying dipole resonance in 11Li close to the breakup threshold.
|
|
| 34. |
- Fernandez-Garcia, J. P., et al.
(författare)
-
11Li Breakup on 208Pb at Energies Around the Coulomb Barrier
- 2013
-
Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 110:14
-
Tidskriftsartikel (refereegranskat)abstract
- The inclusive breakup for the Li-11 + Pb-208 reaction at energies around the Coulomb barrier has been measured for the first time. A sizable yield of Li-9 following the Li-11 dissociation has been observed, even at energies well below the Coulomb barrier. Using the first-order semiclassical perturbation theory of Coulomb excitation it is shown that the breakup probability data measured at small angles can be used to extract effective breakup energy as well as the slope of B(E1) distribution close to the threshold. Four-body continuum-discretized coupled-channels calculations, including both nuclear and Coulomb couplings between the target and projectile to all orders, reproduce the measured inclusive breakup cross sections and support the presence of a dipole resonance in the Li-11 continuum at low excitation energy.
|
|
| 35. |
- Fernandez-Garcia, J. P., et al.
(författare)
-
Li-11 structural information from inclusive break-up measurements
- 2015
-
Ingår i: EPJ Web of Conferences. - : EDP Sciences. - 2101-6275 .- 2100-014X. ; 88
-
Konferensbidrag (refereegranskat)abstract
- Structure information of Li-11 halo nucleus has been obtained from the inclusive break-up measurements of the Li-11+Pb-208 reactions at energies around the Coulomb barrier (E-lab = 24.3 and 29.8 MeV). The effective break-up energy and the slope of B(E1) distribution close to the threshold have been extracted from the experimental data.
|
|
| 36. |
- Borge, M. J. G., et al.
(författare)
-
Scattering of the halo nucleus 11Li and its core 9Li on 208Pb at energies around the Coulomb barrier
- 2012
-
Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 381:1, s. Art. no. 012085-
-
Konferensbidrag (refereegranskat)abstract
- The first measurement of the elastic scattering of the halo nucleus 11Li and its core 9Li on 208Pb at energies around the Coulomb barrier is presented. The 11Li reaction showed a large cross section for the breakup channel, even at energies well below the barrier. The analysis of the 11Li + 208Pb scattering data in terms of the continuum-discretized coupled-channel calculations indicates that the effect of the coupling to the breakup channels produces a strong suppression of the elastic cross section at energies above and below the barrier. This effect is mainly due to the strong Coulomb coupling to the dipole states in the low-lying continuum of 11Li.
|
|
| 37. |
- Borge, M. J. G., et al.
(författare)
-
Scattering of the halo nucleus Li-11 and its core Li-9 on Pb-208 at energies around the Coulomb barrier
- 2012
-
Ingår i: Journal of Physics: Conference Series. - 1742-6588 .- 1742-6596. ; 381
-
Konferensbidrag (refereegranskat)abstract
- The first measurement of the elastic scattering of the halo nucleus Li-11 and its core Li-9 on Pb-208 at energies around the Coulomb barrier is presented. The Li-11 reaction showed a large cross section for the breakup channel, even at energies well below the barrier. The analysis of the Li-11 + Pb-208 scattering data in terms of the continuum-discretized coupled-channel calculations indicates that the effect of the coupling to the breakup channels produces a strong suppression of the elastic cross section at energies above and below the barrier. This effect is mainly due to the strong Coulomb coupling to the dipole states in the low-lying continuum of Li-11.
|
|
| 38. |
- Fernandez-Garcia, J. P., et al.
(författare)
-
Simultaneous analysis of the elastic scattering and breakup channel for the reaction Li-11+Pb-208 at energies near the Coulomb barrier
- 2015
-
Ingår i: Physical Review C - Nuclear Physics. - 2469-9985 .- 2469-9993. ; 92:4
-
Tidskriftsartikel (refereegranskat)abstract
- We present a detailed analysis of the elastic scattering and breakup channel for the reaction of Li-11 on Pb-208 at incident laboratory energies of 24.3 and 29.8 MeV, measured at the radioactive ion beam facility of TRIUMF, in Vancouver, Canada. A large yield of Li-9 fragments was detected by four charged particle telescopes in a wide angular range. The experimental angular and energy distributions of these Li-9 fragments have been compared to coupled-reaction-channel and continuum-discretized coupled-channel calculations. The large production of Li-9 fragments at small angles can be explained by considering a direct breakup mechanism, while at medium-large angles a competition between direct breakup and neutron transfer to the continuum of the Pb-208 target was observed.
|
|
| 39. |
- Fernandez-Garcia, J. P., et al.
(författare)
-
Study of the break-up channel in 11Li+208Pb collisions at energies around the Coulomb barrier
- 2014
-
Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 515:1
-
Konferensbidrag (refereegranskat)abstract
- We present a study of 11Li+208Pb collisions at energies around the Coulomb barrier (Elab 24.3 and 29.8 MeV), measured at the post-accelerated beam facility, ISAC II, at TRIUMF (Vancouver, Canada). A remarkably large yield of 9Li has been observed, a result that is attributed to the weak binding of the 11Li nucleus. The angular distribution of this 9Li yield, relative to the elastic one, has been analysed in terms of first-order semiclassical calculations as well as four-body and three-body Continuum-Discretized Coupled-Channels (CDCC) calculations, based on a three-body and di-neutron model of the 11Li nucleus, respectively. The calculations reproduce well the trend of the data and support the existence of a large concentration of B(E1) strength at very low excitation energies. The connection of this large B(E1) with a possible low-lying dipole resonance is discussed. © Published under licence by IOP Publishing Ltd.
|
|
| 40. |
- Kanungo, S., et al.
(författare)
-
Vibriocidal Antibody Responses to a Bivalent Killed Whole-Cell Oral Cholera Vaccine in a Phase III Trial in Kolkata, India
- 2014
-
Ingår i: Plos One. - : Public Library of Science (PLoS). - 1932-6203. ; 9:5
-
Tidskriftsartikel (refereegranskat)abstract
- Background: During the development of a vaccine, identification of the correlates of protection is of paramount importance for establishing an objective criterion for the protective performance of the vaccine. However, the ascertainment of correlates of immunity conferred by any vaccine is a difficult task. Methods: While conducting a phase three double-blind, cluster-randomized, placebo-controlled trial of a bivalent killed whole-cell oral cholera vaccine in Kolkata, we evaluated the immunogenicity of the vaccine in a subset of participants. Randomly chosen participants (recipients of vaccine or placebo) were invited to provide blood samples at baseline, 14 days after the second dose and one year after the first dose. At these time points, serum geometric mean titers (GMT) of vibriocidal antibodies and seroconversion rates for vaccine and placebo arms were calculated and compared across the age strata (1 to 5 years, 5 to 15 years and more than 15 years) as well as for all age groups. Results: Out of 137 subjects included in analysis, 69 were vaccinees and 68 received placebo. There were 5.7 and 5.8 geometric mean fold (GMF) rises in titers to Vibrio cholerae Inaba and Ogawa, respectively at 14 days after the second dose, with 57% and 61% of vaccinees showing a four-fold or greater titer rise, respectively. After one year, the titers to Inaba and Ogawa remained 1.7 and 2.8 fold higher, respectively, compared to baseline. Serum vibriocidal antibody response to V. cholerae O139 was much lower than that to Inaba or Ogawa. No significant differences in the GMF-rises were observed among the age groups. Conclusions: The reformulated oral cholera vaccine induced a statistically significant anti-O1 Inaba and O1 Ogawa vibriocidal antibody response 14 days after vaccination, which although declined after one year remained significantly higher than baseline. Despite this decline, the vaccine remained protective five years after vaccination.
|
|
| 41. |
|
|
| 42. |
|
|
