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| 2. |
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En båge genom tiden - ritualer kring en göteborgshistoria. Om Flickläroverket i Artisten
- 2024
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- 1929 bildades Göteborgs första Högre allmänna läroverk för Flickor – Flickläroverket som fick en byggnad 1935 i det kulturella centrumet, Götaplatsen. Efter några år som Kjellbergska gymnasiet, sedan Komvux, blev byggnaden del av Artisten, Högskolan för scen och musik, HSM 1992. Byggnaden har burit kvinnors utbildning, konst och kultur över många generationer, en minneskedja som nu är bruten. Boken - En båge genom tiden – ritualer kring en göteborgshistoria – en konst- och forskningsantologi – är resultatet av de offentliga minnesdagar där de deltagande drygt 200 kvinnorna (70– 97 år) som varit elever på Flickläroverket, studenter vid Artisten, konstnärer och forskare – bidrog till och deltog i gestaltande ritualer, minnesrum, dans, utställningar och samtal som gav liv åt en utbildningskultur och konst som berört samhället i generationer. I boken bidrar ett 20-tal Göteborgsbaserade konstnärer och forskare med olika perspektiv på byggnadens poetiska, sociala och konstnärliga dimensioner. Bland annat beskrivs återskapandet av Bågdansen, som dansades varje år vid Lucia mellan 1934-1972. Här beskrivs även den medie-debatt som ledde till räddningen av målningen Dansen av Nils Nilsson från 1935 och hur nedtagningen gick till. Tillsammans med ett rikt foto- och bildmaterial, filmdokumentationer och ett ljudarkiv utgör boken ett tidsdokument där konst fungerar som minnesbärare över tid och rum.
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| 3. |
- Haghighi, Mona, et al.
(författare)
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A Comparison of Rule-based Analysis with Regression Methods in Understanding the Risk Factors for Study Withdrawal in a Pediatric Study
- 2016
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 6
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Tidskriftsartikel (refereegranskat)abstract
- Regression models are extensively used in many epidemiological studies to understand the linkage between specific outcomes of interest and their risk factors. However, regression models in general examine the average effects of the risk factors and ignore subgroups with different risk profiles. As a result, interventions are often geared towards the average member of the population, without consideration of the special health needs of different subgroups within the population. This paper demonstrates the value of using rule-based analysis methods that can identify subgroups with heterogeneous risk profiles in a population without imposing assumptions on the subgroups or method. The rules define the risk pattern of subsets of individuals by not only considering the interactions between the risk factors but also their ranges. We compared the rule-based analysis results with the results from a logistic regression model in The Environmental Determinants of Diabetes in the Young (TEDDY) study. Both methods detected a similar suite of risk factors, but the rule-based analysis was superior at detecting multiple interactions between the risk factors that characterize the subgroups. A further investigation of the particular characteristics of each subgroup may detect the special health needs of the subgroup and lead to tailored interventions.
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| 4. |
- Karlsson, Ingrid, et al.
(författare)
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Coevolution of RANTES sensitivity and mode of CCR5 receptor use by human immunodeficiency virus type 1 of the R5 phenotype.
- 2004
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Ingår i: Journal of Virology. - 1098-5514 .- 0022-538X. ; 78:21, s. 11807-11815
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Tidskriftsartikel (refereegranskat)abstract
- The evolution of human immunodeficiency virus type 1 (HIV-1) coreceptor use has been described as the acquisition of CXCR4 use linked to accelerated disease progression. However, CXCR4-using virus can be isolated only from approximately one-half of individuals with progressive HIV-1 disease. The other half continue to yield only CCR5-using viruses (R5 phenotype) throughout the course of disease. In the present work, the use of receptor chimeras between CCR5 and CXCR4 allowed us to study the evolution of HIV-1 with the R5 phenotype, which was not revealed by studies of wild-type coreceptor use. All together, 246 isolates (173 with the R5 phenotype) from 31 individuals were tested for their ability to infect cells through receptor chimeras. R5narrow virus was able to use only wild-type CCR5, whereas R5broad(1) to R5broad(3) viruses were able to use one to three chimeric receptors, respectively. Broad use of chimeric receptors was interpreted as an increased flexibility in the mode of receptor use. R5broad isolates showed higher infectivity in cells expressing wild-type CCR5 than R5narrow isolates. Also, the increased flexibility of R5broad isolates was concomitant with a lower sensitivity to inhibition by the CC chemokine RANTES. Our results indicate a close relationship between HIV-1 phenotypic changes and the pathogenic process, since the mode and efficiency of CCR5 use as well as the decrease in the RANTES sensitivities of isolated viruses are significantly correlated with CD4+-T-cell decline in a patient. One possible explanation is that ligand competition at the CCR5 receptor or changed CCR5 availability may shape the outcome of HIV-1 infection.
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| 5. |
- Ali, Neserin, et al.
(författare)
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Analysis of nanoparticle-protein coronas formed in vitro between nanosized welding particles and nasal lavage proteins.
- 2016
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Ingår i: Nanotoxicology. - : Taylor & Francis. - 1743-5390 .- 1743-5404. ; 10:2, s. 226-234
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Tidskriftsartikel (refereegranskat)abstract
- Welding fumes include agglomerated particles built up of primary nanoparticles. Particles inhaled through the nose will to some extent be deposited in the protein-rich nasal mucosa, and a protein corona will be formed around the particles. The aim was to identify the protein corona formed between nasal lavage proteins and four types of particles with different parameters. Two of the particles were formed and collected during welding and two were manufactured iron oxides. When nasal lavage proteins were added to the particles, differences were observed in the sizes of the aggregates that were formed. Measurements showed that the amount of protein bound to particles correlated with the relative size increase of the aggregates, suggesting that the surface area was associated with the binding capacity. However, differences in aggregate sizes were detected when nasal proteins were added to UFWF and Fe2O3 particles (having similar agglomerated size) suggesting that yet parameters other than size determine the binding. Relative quantitative mass spectrometric and gel-based analyses showed differences in the protein content of the coronas. High-affinity proteins were further assessed for network interactions. Additional experiments showed that the inhibitory function of secretory leukocyte peptidase inhibitor, a highly abundant nasal protein, was influenced by particle binding suggesting that an understanding of protein function following particle binding is necessary to properly evaluate pathophysiological events. Our results underscore the importance of including particles collected from real working environments when studying the toxic effects of particles because these effects might be mediated by the protein corona.
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| 6. |
- Ali, Neserin, et al.
(författare)
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Comprehensive proteome analysis of nasal lavage samples after controlled exposure to welding nanoparticles shows an induced acute phase and a nuclear receptor, LXR/RXR, activation that influence the status of the extracellular matrix
- 2018
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Ingår i: Clinical Proteomics. - : Springer Science and Business Media LLC. - 1542-6416 .- 1559-0275. ; 15:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: Epidemiological studies have shown that many welders experience respiratory symptoms. During the welding process a large number of airborne nanosized particles are generated, which might be inhaled and deposited in the respiratory tract. Knowledge of the underlying mechanisms behind observed symptoms is still partly lacking, although inflammation is suggested to play a central role. The aim of this study was to investigate the effects of welding fume particle exposure on the proteome expression level in welders suffering from respiratory symptoms, and changes in protein mediators in nasal lavage samples were analyzed. Such mediators will be helpful to clarify the pathomechanisms behind welding fume particle-induced effects. Methods: In an exposure chamber, 11 welders with work-related symptoms in the lower airways during the last month were exposed to mild-steel welding fume particles (1 mg/m3) and to filtered air, respectively, in a double-blind manner. Nasal lavage samples were collected before, immediately after, and the day after exposure. The proteins in the nasal lavage were analyzed with two different mass spectrometry approaches, label-free discovery shotgun LC-MS/MS and a targeted selected reaction monitoring LC-MS/MS analyzing 130 proteins and four in vivo peptide degradation products. Results: The analysis revealed 30 significantly changed proteins that were associated with two main pathways; activation of acute phase response signaling and activation of LXR/RXR, which is a nuclear receptor family involved in lipid signaling. Connective tissue proteins and proteins controlling the degradation of such tissues, including two different matrix metalloprotease proteins, MMP8 and MMP9, were among the significantly changed enzymes and were identified as important key players in the pathways. Conclusion: Exposure to mild-steel welding fume particles causes measurable changes on the proteome level in nasal lavage matrix in exposed welders, although no clinical symptoms were manifested. The results suggested that the exposure causes an immediate effect on the proteome level involving acute phase proteins and mediators regulating lipid signaling. Proteases involved in maintaining the balance between the formation and degradation of extracellular matrix proteins are important key proteins in the induced effects.
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| 7. |
- Allahgholi, Leila, et al.
(författare)
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Fermentation of the Brown Seaweed Alaria esculenta by a Lactic Acid Bacteria Consortium Able to Utilize Mannitol and Laminari-Oligosaccharides
- 2023
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Ingår i: Fermentation. - 2311-5637. ; 9:6
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Tidskriftsartikel (refereegranskat)abstract
- The brown seaweed Alaria esculenta is the second most cultivated species in Europe, and it is therefore of interest to expand its application by developing food products. In this study, a lactic acid bacteria consortium (LAB consortium) consisting of three Lactiplantibacillus plantarum strains (relative abundance ~94%) and a minor amount of a Levilactobacillus brevis strain (relative abundance ~6%) was investigated for its ability to ferment carbohydrates available in brown seaweed. The consortium demonstrated the ability to ferment glucose, mannitol, galactose, mannose, and xylose, of which glucose and mannitol were the most favored substrates. No growth was observed on fucose, mannuronic and guluronic acid. The consortium used different pathways for carbohydrate utilization and produced lactic acid as the main metabolite. In glucose fermentation, only lactic acid was produced, but using mannitol as a carbohydrate source resulted in the co-production of lactic acid, ethanol, and succinate. Xylose fermentation resulted in acetate production. The consortium was also able to utilize laminari-oligosaccharides (DP2-4), obtained after enzymatic hydrolysis of laminarin, and produced lactic acid as a metabolite. The consortium could grow directly on A. esculenta, resulting in a pH decrease to 3.8 after 7 days of fermentation. Incubation of the same seaweed in corresponding conditions without inoculation resulted in spoilage of the seaweed by endogenous bacteria.
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| 8. |
- Allami, Hamid, et al.
(författare)
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Conventional and Nonconventional Use of Idioms in General vs. Academic Corpora of English as a Lingua Franca
- 2022
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Ingår i: Journal of Research in Applied Linguistics. - : Shahid Chamran University of Ahvaz. - 2345-3303 .- 2588-3887. ; 13:1, s. 44-57
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Tidskriftsartikel (refereegranskat)abstract
- The present study investigated the conventional vs. nonconventional use of idioms in general and academic English as a lingua franca (ELF) corpora taking into account the speech event type, academic domain, and discipline. ELFA and VOICE corpora were searched for idiom tokens based on Collins COBUILD Idioms Dictionary. Results showed that idioms were more frequent in VOICE than in ELFA, indicating a higher proportion of formulaic language in informal and interactive discourse as compared to more formal and transactional discourses. Tokens in conventional form and meaning were the most frequent in both corpora. Entirely novel idioms were small in number in both corpora. However, both corpora generated a large number of idioms with formal variations. Idiom use in the academic corpus was register sensitive. ELF speakers in both corpora used communication strategies to prevent unilateral idiomaticity. Overuse of high-frequency idioms by some speakers could be associated with idiomatic teddy bears. Results can help understand the nature of idiomaticity in ELF in general and academic settings. Findings on the academic corpus can also inform curriculum development and assessment in English for Academic Purposes. © 2022 - Published by Shahid Chamran University of Ahvaz. All Rights Reserved.
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| 9. |
- Anter, Karin Fridell, et al.
(författare)
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SYN-TES INTERDISCIPLINARY RESEARCH ON COLOUR AND LIGHT
- 2012
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Ingår i: Proceedings for Interim Meeting of the International Colour Association (AIC); AIC 2012 “In Color We Live: Color and Environment”, 22 – 25 September 2012, Taipei, Taiwan. - : The International Colour Association. ; , s. 80-83, s. 80-83
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Konferensbidrag (refereegranskat)abstract
- Colour and light have largely been considered as belonging to two different fields of knowledge, having disparate theoretical, terminological and methodological traditions. This creates a ground for misunderstandings and obstructs a fruitful interdisciplinary and interprofessional collaboration. A survey over international research literature from 2006 -2011 shows that there has been only little research on the spatial interaction between colour and light, but that the interest for this area has recently increased. The interdisciplinary Nordic research project SYN-TES: Human colour and light synthesis. Towards a coherent field of knowledge was carried out during 2010-11. Colour and light experts from Nordic universities and companies investigated different aspects of the spatial interaction between colour and light and its importance for human beings. This paper deals with the general learnings from the process. Specific results are presented in other papers at this conference.
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| 10. |
- Arver, Brita, et al.
(författare)
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Bilateral Prophylactic Mastectomy in Swedish Women at High Risk of Breast Cancer: A National Survey.
- 2011
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Ingår i: Annals of surgery. - : Lippincott Williams and Wilkins; 1999. - 1528-1140 .- 0003-4932. ; 253:6, s. 1147-1154
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND/OBJECTIVE:: This study attempted a national inventory of all bilateral prophylactic mastectomies performed in Sweden between 1995 and 2005 in high-risk women without a previous breast malignancy. The primary aim was to investigate the breast cancer incidence after surgery. Secondary aims were to describe the preoperative risk assessment, operation techniques, complications, histopathological findings, and regional differences. METHODS:: Geneticists, oncologists and surgeons performing prophylactic breast surgery were asked to identify all women eligible for inclusion in their region. The medical records were reviewed in each region and the data were analyzed centrally. The BOADICEA risk assessment model was used to calculate the number of expected/prevented breast cancers during the follow-up period. RESULTS:: A total of 223 women operated on in 8 hospitals were identified. During a mean follow-up of 6.6 years, no primary breast cancer was observed compared with 12 expected cases. However, 1 woman succumbed 9 years post mastectomy to widespread adenocarcinoma of uncertain origin. Median age at operation was 40 years. A total of 58% were BRCA1/2 mutation carriers. All but 3 women underwent breast reconstruction, 208 with implants and 12 with autologous tissue. Four small, unifocal, invasive cancers and 4 ductal carcinoma in situ were found in the mastectomy specimens. The incidence of nonbreast related complications was low (3%). Implant loss due to infection/necrosis occurred in 21 women (10%) but a majority received a new implant later. In total, 64% of the women underwent at least 1unanticipated secondary operation. CONCLUSIONS:: Bilateral prophylactic mastectomy is safe and efficacious in reducing future breast cancer in asymptomatic women at high risk. Unanticipated reoperations are common. Given the small number of patients centralization seems justified.
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| 11. |
- Badia, J. D., et al.
(författare)
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Effect of sisal and hydrothermal ageing on the dielectric behaviour of polylactide/sisal biocomposites
- 2017
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Ingår i: Composites Science And Technology. - : Elsevier. - 0266-3538 .- 1879-1050. ; 149, s. 1-10
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Tidskriftsartikel (refereegranskat)abstract
- The dielectric properties of virgin polylactide (PLA) and its reinforced composites with different weight amounts of sisal fibres were assessed at broad temperature (from −130 °C to 130 °C) and frequency ranges (from 10−2–107 Hz), before and after being subjected to accelerated hydrothermal ageing. The synergetic effects of both the loading of sisal and hydrothermal ageing were analysed by means of dielectric relaxation spectra. The relaxation time functions were evaluated by the Havriliak-Negami model, substracting the ohmic contribution of conductivity. The intramolecular and intermolecular relaxations were respectively analysed by means of Arrhenius and Vogel-Fulcher-Tammann-Hesse thermal activation models. The addition of fibre increased the number of hydrogen bonds, which incremented the dielectric permittivity and mainly hindered the non-cooperative relaxations of the biocomposites by increasing the activation energy. Hydrothermal ageing enhanced the formation of the crystalline phase at the so-called transcrystalline region along sisal. This fact hindered the movement of the amorphous PLA fraction, and consequently decreased the dielectric permittivity and increased the dynamic fragility.
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| 12. |
- Badia, J. D., et al.
(författare)
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Relevant factors for the eco-design of polylactide/sisal biocomposites to control biodegradation in soil in an end-of-life scenario
- 2017
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Ingår i: Polymer degradation and stability. - : Elsevier. - 0141-3910 .- 1873-2321. ; 143, s. 9-19
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Tidskriftsartikel (refereegranskat)abstract
- The eco-design considers the factors to prepare biocomposites under an end-of-life scenario. PLA/sisal biocomposites were obtained from amorphous polylactide and sisal loadings of 10, 20 and 30 wt% with and without coupling agent, and subjected to biodegradation in soil according to standard ISO846. Mass-loss, differential scanning calorimetry and size-exclusion chromatography were used for monitoring biodegradation. A statistical factorial analysis based on the molar mass Mn and crystallinity degree XC pointed out the relevance and interaction of amount of fibre and use of coupling agent with the time of burial in soil. During the preparation of biocomposites, chain scission provoked a similar reduction of Mn for coupled and non-coupled biocomposites. The amount of fibre was relevant for the increase of XC due to the increase of nucleation sites. The coupling agent accelerated the evolution of both factors: reduction of Mn and the consequent increase of XC, mainly during biodegradation in soil. Both factors should be balanced to facilitate microbial assimilation of polymer segments, since bacterial digestion is enhanced by chain scission but blocked by the promotion of crystalline fractions.
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| 13. |
- Badia, J. D., et al.
(författare)
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Water absorption and hydrothermal performance of PHBV/sisal biocomposites
- 2014
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Ingår i: Polymer degradation and stability. - : Elsevier BV. - 0141-3910 .- 1873-2321. ; 108, s. 166-174
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Tidskriftsartikel (refereegranskat)abstract
- The performance of biocomposites of poly(hydroxybutyrate-co-valerate) (PHBV) and sisal fibre subjected to hydrothermal tests at different temperatures above the glass transition of PHBV (T-H = 26, 36 and 46 degrees C) was evaluated in this study. The influences of both the fibre content and presence of coupling agent were focused. The water absorption capability and water diffusion rate were considered for a statistical factorial analysis. Afterwards, the physico-chemical properties of water-saturated biocomposites were assessed by Fourier-Transform Infrared Analysis, Size Exclusion Chromatography, Differential Scanning Calorimetry and Scanning Electron Microscopy. It was found that the water diffusion rate increased with both temperature and percentage of fibre, whereas the amount of absorbed water was only influenced by fibre content. The use of coupling agent was only relevant at the initial stages of the hydrothermal test, giving an increase in the diffusion rate. Although the chemical structure and thermal properties of water-saturated biocomposites remained practically intact, the physical performance was considerably affected, due to the swelling of fibres, which internally blew-up the PHBV matrix, provoking cracks and fibre detachment.
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| 14. |
- Berggren, Monica, 1966-, et al.
(författare)
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Effects of geriatric interdisciplinary home rehabilitation on complications and readmissions after hip fracture : a randomized controlled trial
- 2019
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Ingår i: Clinical Rehabilitation. - : Sage Publications. - 0269-2155 .- 1477-0873. ; 33:1, s. 64-73
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Tidskriftsartikel (refereegranskat)abstract
- Objective: This pre-planned secondary analysis of geriatric interdisciplinary home rehabilitation, which was initially found to shorten the postoperative length of stay in hospital for older individuals following hip fracture, investigated whether such rehabilitation reduced the numbers of complications, readmissions, and total days spent in hospital after discharge during a 12-month follow-up period compared with conventional geriatric care and rehabilitation.Design: Randomized controlled trial.Setting: Geriatric department, participants' residential care facilities, and ordinary housing.Subjects: Individuals aged ⩾70 years with acute hip fracture (n = 205) were included.Intervention: Geriatric interdisciplinary home rehabilitation was individually designed and aimed at early discharge with the intention to prevent, detect, and treat complications after discharge.Main measures: Complications, readmissions, and days spent in hospital were registered from patients' digital records and interviews conducted during hospitalization and at 3- and 12-month follow-up visits.Results: No significant difference in outcomes was observed. Between discharge and the 12-month follow-up, among participants in the geriatric interdisciplinary home rehabilitation group (n = 106) and control group (n = 93), 57 (53.8%) and 44 (47.3%) had complications (P = 0.443), 46 (43.4%) and 38 (40.9%) fell (P = 0.828), and 38 (35.8%) and 27 (29.0%) were readmitted to hospital (P = 0.383); the median total days spent in hospital were 11.5 and 11.0 (P = 0.353), respectively.Conclusion: Geriatric interdisciplinary home rehabilitation for older individuals following hip fracture resulted in similar proportions of complications, readmissions, and total days spent in hospital after discharge compared with conventional geriatric care and rehabilitation.
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| 15. |
- Berglund, Anders, et al.
(författare)
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Innopoly : Design Steps Towards Proficiency in Innovative Practices
- 2011
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Ingår i: Proceedings of the 13th International Conference on Engineering and Product Design Education E&PDE11. - : the Design society. - 9781904670339 ; , s. 281-286
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Konferensbidrag (refereegranskat)abstract
- This paper is a follow-up on last year’s design steps and case studies analysis to bundle innovation skills in an educational model. In our previous research we presented the ideas and construct foundations to a game plan ideology to build up common knowledge and examine innovativeness. In this, the next phase paper, our ambitions is to deepen students’ abilities for self-governed innovative practices within a team. We have used a series of workshops with engineering design students and design students to frame and concretize the ‘Innovopoly’ educational platform. But also to find a way of communicate a coveted and sustainable knowledge and to motivate the learning since it will affect the momentum of a self-driven learning process. The implementation efforts of specific interdisciplinary design elements aim to strengthen the acknowledgement of how to perform a common and open innovative process and a holistic perspective. In order to do that, Innopoly has a three-dimensional concept based on four process phases and four different layers that can be varied according to level, how the team solves the defined task but also from the effect of an unknown factor in the game. Firstly, Innopoly put emphasis on the team process and team requirements as individual and mutual accountability, commitment to a common purpose, shared leadership and autonomy. Secondly, the game integrates the divergence of the team with a creative process where different knowledge backgrounds and experiences can open up a broader set of perspectives and refinements of ideas for each individual. Thirdly, Innopoly put the focus on external factors like working environment and visual and concrete working techniques and methods that can affect teams' work process. Fourthly, the involvement with organisations and industry in the task definition and also the idea that industry people can work together with the students when they perform the game give a realistic and up to date knowledge to the students in the learning context. The iterative process provides a greater understanding and anchoring knowledge through reflection and students' common discussion. The education model, ‘Innopoly’, builds on student-oriented learning, derived in design situations and situated practices. The ambitions to examine innovative practices are redeemed in incorporation of skills applied to manifest an autonomy level of performance and integrity. ‘Innopoly’ carries the outline logics from the innovation process – identification, research, ideation, concept, prototyping, testing and commercialization similar to the value increase as can be back traced to the original game form. The knowledge construction is supported in their performance, behaviour, thinking and reflections during all four phases. The educational prototype ‘Innopoly’ comprises of an inclination model inspired from Bloom’s taxonomy where ambitions is to prepare our students for future challenges.
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| 17. |
- Boukhelifa, Malika, et al.
(författare)
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The proline-rich protein palladin is a binding partner for profilin
- 2006
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Ingår i: The FEBS Journal. - : Wiley. - 1742-464X .- 1742-4658. ; 273:1, s. 26-33
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Tidskriftsartikel (refereegranskat)abstract
- Palladin is an actin-associated protein that has been suggested to play critical roles in establishing cell morphology and maintaining cytoskeletal organization in a wide variety of cell types. Palladin has been shown previously to bind directly to three different actin-binding proteins vasodilator-stimulated phosphoprotein (VASP), α-actinin and ezrin, suggesting that it functions as an organizing unit that recruits actin-regulatory proteins to specific subcellular sites. Palladin contains sequences resembling a motif known to bind profilin. Here, we demonstrate that palladin is a binding partner for profilin, interacting with profilin via a poly proline-containing sequence in the amino-terminal half of palladin. Double-label immunofluorescence staining shows that palladin and profilin partially colocalize in actin-rich structures in cultured astrocytes. Our results suggest that palladin may play an important role in recruiting profilin to sites of actin dynamics.
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| 18. |
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| 19. |
- Creed, Irena F., et al.
(författare)
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Global change-driven effects on dissolved organic matter composition : Implications for food webs of northern lakes
- 2018
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Ingår i: Global Change Biology. - : Wiley. - 1354-1013 .- 1365-2486. ; 24:8, s. 3692-3714
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Forskningsöversikt (refereegranskat)abstract
- Northern ecosystems are experiencing some of the most dramatic impacts of global change on Earth. Rising temperatures, hydrological intensification, changes in atmospheric acid deposition and associated acidification recovery, and changes in vegetative cover are resulting in fundamental changes in terrestrial-aquatic biogeochemical linkages. The effects of global change are readily observed in alterations in the supply of dissolved organic matter (DOM)-the messenger between terrestrial and lake ecosystems-with potentially profound effects on the structure and function of lakes. Northern terrestrial ecosystems contain substantial stores of organic matter and filter or funnel DOM, affecting the timing and magnitude of DOM delivery to surface waters. This terrestrial DOM is processed in streams, rivers, and lakes, ultimately shifting its composition, stoichiometry, and bioavailability. Here, we explore the potential consequences of these global change-driven effects for lake food webs at northern latitudes. Notably, we provide evidence that increased allochthonous DOM supply to lakes is overwhelming increased autochthonous DOM supply that potentially results from earlier ice-out and a longer growing season. Furthermore, we assess the potential implications of this shift for the nutritional quality of autotrophs in terms of their stoichiometry, fatty acid composition, toxin production, and methylmercury concentration, and therefore, contaminant transfer through the food web. We conclude that global change in northern regions leads not only to reduced primary productivity but also to nutritionally poorer lake food webs, with discernible consequences for the trophic web to fish and humans.
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| 20. |
- Danelid, Hans, et al.
(författare)
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Kartläggning av högskolans elektroniska publicering och rekommendationer för nationell samverkan : Återrapportering till SUHF:s Forum för bibliotekschefer
- 2008
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Resultatet av arbetsgruppens genomförda kartläggning av e-publicering visar att den stora utmaningen för de flesta av SUHF:s medlemmar som idag driver system för e-publicering är att marknadsföra och förankra detta arbete. Det finns svårigheter att nå ut till anställda på det sätt som krävs för att få igång fungerande arbetsflöden och ökad digital publicering. Därför är det nu viktigt att fortsätta utvecklingen med att skapa en bredare förankring vid universitet och högskolor. Kartläggningen visar vidare att intresset för nationell samordning av elektro-nisk publicering är stort hos de lokalt ansvariga för publiceringsfrågor. Här har SUHF en vik-tig funktion att fylla för att bistå med förankring och samordning.Arbetsgruppen för Högskolans elektroniska publicering rekommenderar följande fortsatta åtgärder för nationell samverkan via SUHF/Forum för bibliotekschefer:• SUHF tar ansvar för en permanent övergripande och nationell samverkan kring hög-skolans elektroniska publicering.• SUHF formulerar riktlinjer till lärosätenas ledningar för hur elektronisk publicering, publiceringsredovisning och Open Access kan införlivas i lärosätenas verksamhet.• SUHF bör försöka hitta gemensamma finansieringsformer för funktioner där samord-ning är angelägen.
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| 21. |
- Daugbjerg Christensen, Monica, et al.
(författare)
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Cloning and Characterization of a Novel N-Acetyl-D-galactosamine-4-O-sulfate Sulfatase, SulA1, from a Marine Arthrobacter Strain
- 2024
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Ingår i: Marine Drugs. - 1660-3397. ; 22:3
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Tidskriftsartikel (refereegranskat)abstract
- Sulfation is gaining increased interest due to the role of sulfate in the bioactivity of many polysaccharides of marine origin. Hence, sulfatases, enzymes that control the degree of sulfation, are being more extensively researched. In this work, a novel sulfatase (SulA1) encoded by the gene sulA1 was characterized. The sulA1-gene is located upstream of a chondroitin lyase encoding gene in the genome of the marine Arthrobacter strain (MAT3885). The sulfatase was produced in Escherichia coli. Based on the primary sequence, the enzyme is classified under sulfatase family 1 and the two catalytic residues typical of the sulfatase 1 family—Cys57 (post-translationally modified to formyl glycine for function) and His190—were conserved. The enzyme showed increased activity, but not improved stability, in the presence of Ca2+, and conserved residues for Ca2+ binding were identified (Asp17, Asp18, Asp277, and Asn278) in a structural model of the enzyme. The temperature and pH activity profiles (screened using p-nitrocatechol sulfate) were narrow, with an activity optimum at 40–50 °C and a pH optimum at pH 5.5. The Tm was significantly higher (67 °C) than the activity optimum. Desulfation activity was not detected on polymeric substrates, but was found on GalNAc4S, which is a sulfated monomer in the repeated disaccharide unit (GlcA–GalNAc4S) of, e.g., chondroitin sulfate A. The position of the sulA1 gene upstream of a chondroitin lyase gene and combined with the activity on GalNAc4S suggests that there is an involvement of the enzyme in the chondroitin-degrading cascade reaction, which specifically removes sulfate from monomeric GalNAc4S from chondroitin sulfate degradation products.
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| 22. |
- Dedic, Dina, 1985-
(författare)
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The warship Vasa : A Study of Lignin, Extractives and Acids in the oak wood
- 2013
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The oak wood timbers of the 17th century Swedish warship Vasa are weak. The weakening has been attributed to cellulose degradation, which is more extensive in the interior of the timbers compared to the surface regions. Further, the mechanism of cellulose degradation was attributed to oxidative reactions involving iron as a catalyst. In this work, the non-cellulosic wood components (lignin and extractives) in the wood of the Vasa have been studied in order to assess the level of degradation possibly caused by oxidative reactions. Because the interior of the wood timbers is more acidic and its cellulose more depolymerized than at the near surface regions, a general study of organic acidand iron concentrations with respect to different depths from the surface was also performed.Characterization of lignin in the wood of the Vasa was done by means of wet chemical degradation (thioacidolysis) and subsequent GC-MS analysis of the degradation products, as well as CP/MAS 13C NMR spectroscopy of the wood. Dry acetone- and water extracts of the wood were analyzed by 13C NMR spectroscopy and MALDI-TOF mass spectroscopy in order to study the presence of gallo- and ellagitannins. No severe lignin degradation and no discernible amounts of hydrolysable tannins in the oak wood of the Vasa were detected, indicating that oxidative reactions are not the primary route to cellulose depolymerization.High amounts of oxalic acid (analyzed by HPIEC) and a low pH have been found in the interior of the wood timbers, supporting acid hydrolysis as the main mechanism of cellulose depolymerization. Analysis of the iron distribution using ICP AES shows that iron is most abundant in the surface of the timbers and decreases as the concentration of oxalic acid increases. Experimental work also shows that some iron species (rust) in the Vasa neutralize oxalic acid, thereby protecting the surface wood from acid hydrolysis.
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| 23. |
- Ek, Monica, et al.
(författare)
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CELL 28-Biointeractive fibers with antibacterial properties
- 2008
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Ingår i: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. ; , s. 28-CELL-
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Konferensbidrag (refereegranskat)abstract
- Growth of bacteria on various surfaces may cause major concern if encountered in the wrong environment. The ability to impart antimicrobial properties onto surfaces is therefore desirable. Modification of both glass surfaces and cellulose membranes using weak polyelectrolytes as antimicrobial agent is presented. The aim was to incorporate a known carrier of antimicrobial activity into a multilayer structure of adsorbed polyelectolytes at different surfaces and evaluate the antibacterial activities. The approach involved screening for antimicrobial activity in soln. of modified and unmodified polymers. The polymers were evaluated against gram-neg. E. coli and gram-pos. B. subtilis. In order to elucidate the mode of action of the polymers, the charge was detd. This is done since earlier studies have shown that both charge and degree of hydrophobicity are of importance in terms of exerted activity. Results show that the chosen polymers exert activity in the immobilized state. Different techniques have been used to evaluate the mechanisms.
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| 24. |
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| 25. |
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| 26. |
- Ek, Monica, et al.
(författare)
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New cellulose derivatives from wood for high value products
- 2008
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Ingår i: TAPPSA: Technical Association of the Pulp and Paper Industry of Southern Africa. - 1029-0109. ; :September 2008
-
Tidskriftsartikel (refereegranskat)abstract
- Various pre-treatment methods to increase the accessibility of cellulose materials to swelling and reactive agents at different hierarchical levels, has been developed. It was demonstrated that enzymes are very efficient at increasing the cellulose reactivity. A new method to measure the reactivity and accessibility of the hydroxyl groups on cellulose was developed. Reversible addition-fragmentation chain transfer (RAFT) agents were synthesized and used further in esterification reactions with cellulose samples to prepare cellulose based graft-copolymers. MALDI-TOFMS was evaluated for characterization of cellulose derivatives. Methods to prepare electrospun fibres, casings, sponges and beads, were developed with target applications in pharmaceuticals and foods.
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| 27. |
- Eklund Karlsson, Leena, 1956-, et al.
(författare)
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Salutogenesis and empowerment as prominent approaches for a sustainable health promotion : Some theoretical comparisons
- 2011
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Ingår i: Health Technology Assessment Society (HTAi). ; , s. 294-
-
Konferensbidrag (refereegranskat)abstract
- Extensive evidence proposes Antonovsky’s salutogenic theory as a pathway to health promotion. The fundamental concept of salutogenesis is Sense of Coherence (SOC). Salutogenesis is defined as the process of movement towards the health-end of the health ease/dis-ease continuum. The aim of empowerment is to reduce inequity through a learning process and mobilize the uneducated for social action. Empowerment is defined as a process enabling the people to increase control over their health determinants. Empowerment still lacks a coherent theoretical basis. It is claimed that empowerment and SOC have much common and are sometimes overlapping. However, the relationship between these concepts has not been verified by research.Objectives: To compare the salutogenic theory with the empowerment concept and approach.Methods: Data consists of a worldwide systematic research synthesis (1992-2003) including 471 scientific publications and an on-going follow-up to 2010. The search was performed through PubMed, Libris, ISI, PsychInfo, Cinahl, Social Services Abstracts and Sociological Abstracts. The analysis was conducted by comparing selected indicators of both theories, such as approach, theoretical focus, definitions, orientation, key concepts, measurement instruments, outcomes and applicability.Findings: There are both similarities and differences between the concepts, which also somewhat overlap. Several unique and distinctive features for each concept were found. Salutogenesis is based on stress theories whereas empowerment has its roots in pedagogy and social psychology. Both concepts are process oriented. Empowerment can be seen as both means and an outcome whereas salutogenesis is a global life-orientation. Both concepts can be applied at the individual, group, health systems and societal levels. Both proved to be effective in promoting health. The two concepts differ when it comes to definitions and theoretical foundations.Conclusion: Both approaches are promising methods that can lead to improved health outcomes and are seen as viable public health strategies.
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| 28. |
- Ekman, Anna, et al.
(författare)
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Bioresource utilisation by sustainable technologies in new value-added biorefinery concepts - two case studies from food and forest industry
- 2013
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Ingår i: Journal of Cleaner Production. - : Elsevier BV. - 0959-6526 .- 1879-1786. ; 57, s. 46-58
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents a trans-disciplinary assessment of new and innovative biorefinery concepts producing high-value chemical compounds from residues from agriculture, food and forest industries. There is a significant potential of biomass residues in Sweden suitable for the extraction of various compounds, including upgrading by biocatalytic processes, in addition to current energy generation. Two examples presented are quercetin extracted from onion waste by pressurised hot water in conjunction with enzymatic hydrolysis, and betulin from birch bark extracted by liquid CO2 containing ethanol. Inherent in these two extraction processes and production routes is the ability to show good environmental performance from a life cycle perspective. Extraction of high-value compounds also provides possibilities for innovation in the current agricultural, food and forest industry potentially leading to socio-economical benefits. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.
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| 29. |
- Engström, Christer, et al.
(författare)
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Relationship between prophylactic effect of lithium therapy and family history of affective disorders
- 1997
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Ingår i: Biological Psychiatry. - 0006-3223 .- 1873-2402. ; 42:6, s. 425-433
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Tidskriftsartikel (refereegranskat)abstract
- Lithium therapy response and age of onset (AOO) were studied in 98 patients with bipolar affective disorder (BPAD) who were divided into subgroups depending on type of family history of affective disorders. The highest (33.0 years) and lowest (25.5 years) age of onset were found in nonfamilial patients and in familial patients with a first-degree relative of BPAD, respectively. Nonfamilial patients showed the best response to lithium. There were 0.9 episodes/year off lithium compared to 0.3 episodes/year on lithium (an 88% decrease). A poorer response (a 71% decrease; a reduction from 1.39 episodes per year off lithium to 0.65 on lithium) was found in familial patients with a first-degree relative of BPAD. Differences in serum lithium values between the groups could not explain the observed differences. Thus, familial patients showed a more severe manifestation of the disease with an earlier AOO and a lower prophylactic effect of lithium.
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| 30. |
- Enstedt, Ulla, et al.
(författare)
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Samtalsminne : erinringar från gruppsamtal efter sju dagar
- 2000
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Syftet är att undersöka vilka fel som kan uppstå vid erinring från gruppsamtal, då erinring sker efter sju dagar. Tre halvtimmeslånga gruppsamtal med sex deltagare i varje grupp spelades in. Efter sju dagar fick de skriva ner vad som sagts och vem som sagt det. Resultatet visar att tillkommande uppgift, förvrängning och källförväxling är de tre mest förekommande felaktiga erinringarna i undersökningen. Överdrift och nedtoning tillsammans med generalisering förekommer i mindre omfattning än övriga felaktiga erinringar. I två av samtalen härrör de flesta erinringarna från den första tredjedelen i ursprungssamtalet. I det tredje samtalet åferfinns lika många erinringar från den första och den tredje tredjedelen.
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| 31. |
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| 32. |
- Gellerstedt, Linda, et al.
(författare)
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Nurses' experiences of hospitalised patients' sleep in Sweden : a qualitative study
- 2015
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Ingår i: Journal of Clinical Nursing. - : Wiley. - 0962-1067 .- 1365-2702. ; 24:23/24, s. 3664-3673
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Tidskriftsartikel (refereegranskat)abstract
- AIMS AND OBJECTIVES:The aim was to describe nurses' experiences of patients' sleep at an emergency hospital and their perceptions of sleep-promoting interventions.BACKGROUND:Promotion of patients' sleep during hospital care is an important intervention for the nursing profession. To promote sleep and to initiate sleep-promoting interventions, nurses need basic knowledge about sleep and its physiology. Therefore, it is of importance to explore and expand knowledge about how nurses experience patients' sleep and how they perceive working with it while providing care.DESIGN:A qualitative descriptive design was used.METHODS:Data were collected from four focus groups and seven individual interviews. A total of twenty-two registered nurses participated. Data were analysed using a qualitative content analysis.RESULTS:Nurses expressed a desire and an ambition to work in ways that promote patients' sleep during hospitalisation. Nurses reported that health care services and emergency hospitals were not organised according to patients' perspective and needs. Furthermore, they did not have opportunities to work effectively to promote sleep according to the patients' wishes. Several nurses stated that they did not have sufficient knowledge about sleep and that they did the best they could under prevailing circumstances. Nurses emphasised the importance of sleep for patients and that it was an area that should be given far greater priority.CONCLUSIONS:The results indicate that nurses currently have insufficient knowledge about sleep and sleep-promoting interventions. These aspects of nursing is based on personal experience and common sense rather than being evidence based. Furthermore, sleep as a nursing topic needs to be developed and given more focus in order for nurses to be able to deliver high quality care at emergency hospitals.RELEVANCE TO CLINICAL PRACTICE:Nurses require more knowledge and education to gain deeper understanding of sleep and to deliver evidence-based, high quality care.
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| 33. |
- Gellerstedt, Linda, et al.
(författare)
-
Nursing care and management of patients' sleep during hospitalisation : a cross-sectional study
- 2019
-
Ingår i: Journal of Clinical Nursing. - : Wiley. - 0962-1067 .- 1365-2702. ; 28:19-20, s. 3400-3407
-
Tidskriftsartikel (refereegranskat)abstract
- AIM: To explore and describe how patients' sleep is addressed at acute-care hospitals in Sweden with regard to nursing care, management, and the development of knowledge in this area.BACKGROUND: Sleep is a basic human need and thus important for health and health maintenance. Patients describe sleeping in hospital as a stressor, and research shows that nurses tend to underestimate patients' perceived problems with sleep during hospitalization. How do nursing staff at acute hospitals address patients' sleep and the development of knowledge in this area?.DESIGN/METHOD: A cross-sectional descriptive study was conducted based on data collected through a web survey. Head nurses, registered nurses, nursing care developers, and local training supervisors at 36 randomized acute-care hospitals in Sweden were invited to participate. This study was executed and reported in accordance with SQUIRE 2.0.RESULTS: The results of the survey (53 responses from 19 wards at 15 acute-care hospitals) showed that no policy documents exist and no current training addresses sleep during hospital stay. All participants agreed that sleep should be considered a nursing topic and that it is important for hospitalized patients.CONCLUSION: Patients' sleep during hospitalization is undermanaged at acute-care hospitals. Nurses, health care managers, and organizations face challenges if they are to achieve better outcomes.RELEVANCE TO CLINICAL PRACTICE: This study shows that nurses do consider patients' sleep important and addressing sleep as part of nursing care. Future studies in the area should focus on what kinds of support and education are needed in the clinical context. This article is protected by copyright. All rights reserved.
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| 34. |
- Gellerstedt, Linda
(författare)
-
Nursing perspectives on patients' sleep during hospital care
- 2019
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Sleep is crucial for all humans in terms of health, daily functioning and well-being. Previous research has shown that sleep is considered a stressor for patients during hospital care. The general aim of this thesis was to explore and describe, from a nursing perspective, patients’ sleep and how sleep is addressed, promoted and assessed during hospital care.Methods: To cover the general aim of this thesis, various designs were chosen, and diverse methods of data collection were employed. In Study I, data were collected through qualitative interviews of ten consecutively recruited patients at an acute hospital. In Study II, data were collected through qualitative individual interviews and four focus groups, with a total of twenty-two registered nurses at four acute hospitals in an urban region. Study III was designed as a mixed method study and data were collected through twenty-one qualitative individual interviews as well as from program and course syllabuses and intended learning outcomes at three universities. Data from Studies I-II were analysed by qualitative content analysis with an inductive, latent approach. Data in Study III were analysed by qualitative content analysis with an inductive, manifest approach and collected documents were read word-for-word and scanned for the pre-set word, sleep. Study IV was a cross-sectional study and data were collected through a web-based survey. Acute hospitals in Sweden were subjected to stratified randomized sampling. Registered nurses, head nurses, nursing care developers and local training staff were included in the study. Data were analysed using descriptive statistics, and free-text answers were analysed by a thematic text analysis. Study V was performed as a non-experimental prospective study. Data from a group of twenty-five patients at two hospitals were collected by using the Richards-Campbell Sleep Questionnaire and actigraphy by Vivago® and were analysed with correlation and regression analysis.Findings: Patients’ sleep during hospital care is affected by several different factors and patients’ sleep is described as an important but undermanaged area. Limited knowledge and education within the area and insufficient support from the organization can be seen as barriers. Study III reveals that several student nurses lack evidence-based knowledge about sleep and sleep-promotion and consider themselves only to be prepared to address and promote sleep to a limited extent. Furthermore, the word, sleep, occurred explicitly only three times in two different learning outcomes at one of three included universities. Study IV shows that the area of sleep is not highlighted in a clinical context; for example, there is an absence of training days and education about sleep, only a few departments actively address patients’ sleep, and the use of sleep-assessment is non-existent. Study V shows a relationship between individual Vivago® graphs and patients’ self-assessed sleep, but a significant correlation for all patients between mean values for the two assessments was only obtained for one of the two included nights.Conclusions: This thesis indicates that sleep deprivation is common among patients during hospital care. Furthermore, education about patients’ sleep in the investigated nursing programs and in clinical practice seems to be deficient. Assessments with the Richards-Campbell Sleep Questionnaire and measurement with Vivago® capture different dimensions of sleep. In its present form, the RCSQ could have the potential to facilitate nursing actions to promote sleep amongst hospitalized patients in line with person-centred care. Furthermore, it is concluded that patients’ sleep during hospital care is an undermanaged and non-highlighted area. This thesis shows that there are several challenges for nurses, nursing managers and organizations at acute hospitals if better outcomes are to be achieved.
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| 35. |
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| 36. |
- Gellerstedt, Linda, et al.
(författare)
-
Patient's experiences of sleep in hospital : a qualitative interview study
- 2014
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Ingår i: Journal of Research in Nursing. - : SAGE Publications. - 1744-9871 .- 1744-988X. ; 19:3, s. 176-188
-
Tidskriftsartikel (refereegranskat)abstract
- Many patients experience sleep disturbances and a reduced quality of sleep while hospitalised. Studies have shown that a person with a disease and/or a bodily injury has an increased need for sleep. Patients' experiences of sleep should govern how sleep disturbances should be managed. It is thus necessary to focus upon and describe patients’ needs and experiences. The aim of this study was to explore and describe patients’ experiences of sleeping in hospital. This study is based on qualitative semi-structured interviews with 10 consecutively included patients. The interviews were conducted between October 2010 and March 2011 and were audio recorded and transcribed verbatim. Collected data were analysed by qualitative content analysis. The participants reported physical and psychological experiences that had affected their sleep. Their experiences were categorised using four themes: bedside manner, physical factors, being involved and integrity. Patients considered that experiencing some degree of control, feeling involved and preserving one’s integrity affect sleep during hospitalisation. Several factors have an impact on patients’ sleep. It is not only physical factors but also psychological factors such as bedside manner and having the opportunity to influence and be involved. The patients’ accounts provide a new perspective and open the door to changes in nursing care regarding patients’ sleep.
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| 37. |
- Gellerstedt, Linda, et al.
(författare)
-
Patients’ self-assessed sleep as a nursing tool during hospital care : A pilot study
- 2020
-
Ingår i: Nordic journal of nursing research. - : Sage Publications. - 2057-1585 .- 2057-1593. ; 40:3, s. 123-129
-
Tidskriftsartikel (refereegranskat)abstract
- Sleep in hospital is considered a challenge from both a patient and a nursing perspective. To enable nurses to promote patients? sleep during hospital care it is essential to have valid, reliable and useful sleep assessment tools at hand. The aim of the present study was to evaluate and compare the outcomes of objectively estimated sleep and self-reported sleep quality. Data were collected through continuous wrist-worn actigraphy and completion of the Richards?Campbell Sleep Questionnaire (RCSQ) in a pilot study on 25 patients during hospital care. A correlation between mean values for the two assessments was shown for the second night but not for the third night of assessment, and it was concluded that the two assessments might capture different dimensions of sleep. Furthermore, based on a high response rate and an evident feasibility in a nursing context the RCSQ may facilitate person-centered care.
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| 38. |
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| 39. |
- Gellerstedt, Linda, et al.
(författare)
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Sleep as a topic in nursing education programs? A mixed method study of syllabuses and nursing students' perceptions
- 2019
-
Ingår i: Nurse Education Today. - : Elsevier BV. - 0260-6917 .- 1532-2793. ; 79, s. 168-174
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Sleep is a basic human need and is considered important for maintaining health. It is even more important during illness due to its impact for example on our immune system. Nurses have an important role in identifying sleep deprivation. They are also in a unique position to promote and address sleep among patients. However, it is essential that they are provided with the appropriate knowledge during training.AIM: To explore and describe nursing students' perceptions of preparedness to adress and support patients' sleep during hospitalization and to apply sleep-promoting interventions in a clinical context. Furthermore, the aim was to investigate if, and how, the topic of sleep is explicitly incorporated in nursing education programs.DESIGN: A descriptive study based on a mixed method approach.METHODS: Quantitative and qualitative data were collected from program and course syllabuses and intended learning outcomes from three universities. Twenty-one nursing students from the same universities were interviewed during their final year of education.RESULTS: The results of both quantitative and qualitative data consistently show that education regarding sleep and patients' sleep is limited and, in some respects, absent in the Bachelor of Science Nursing programs investigated.CONCLUSION: This study indicates that education about sleep and patients' sleep in the nursing programs studied is insufficient and limited. This gap in knowledge may lead to prospective registered nurses using their own experiences instead of evidence-based knowledge when assessing, supporting and applying sleep-promoting interventions.
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| 40. |
- Ghahraman, Vahid, et al.
(författare)
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On the functions of hedging in research articles (RAs): A study on RA discussions
- 2023
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Ingår i: International Journal of Language Studies. - : Lulu Press Inc. - 2157-4898 .- 2157-4901. ; 17:1, s. 165-187
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Tidskriftsartikel (refereegranskat)abstract
- The current study aimed at finding probable differences between native-Persian-speaking (n = 72) and native-English-speaking (n = 72) academic writers’ use of hedging devices in the ‘discussion’ sections of research articles (RAs). 144 RA discussions from Persian-text Iranian academic journals published by Iranian state universities and English-text foreign academic journals published by several famous international academic publishers were randomly selected. The publication dates of the RAs ranged from 2017 to 2022. Using a counter-balanced design, two human coders identified and coded the functions of hedging devices in the corpus according to the theoretical framework proposed by Hyland (1998). Results indicated that Iranian authors of Persian-text RAs systematically use much fewer hedging devices in their discussions than their foreign counterparts. It is argued that this pattern might be due to Iranian RA authors’ (a) personality traits, (b) incompetence in academic writing, or (c) cultural mindset. The paper concludes that professional workshops in which native-Persian-speaking authors are taught to be aware of the importance of hedging devices in academic writing might be necessary and that journal editors should also have an eye on the use of hedging in the process of screening the manuscripts they receive for possible publication in the journals they edit.
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| 41. |
- Gil-Castell, O., et al.
(författare)
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Hydrothermal ageing of polylactide/sisal biocomposites. Studies of water absorption behaviour and Physico-Chemical performance
- 2014
-
Ingår i: Polymer degradation and stability. - : Elsevier BV. - 0141-3910 .- 1873-2321. ; 108, s. 212-222
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Tidskriftsartikel (refereegranskat)abstract
- An accelerated hydrothermal degrading test was designed in order to analyse the synergic effect of water and temperature on PLA/sisal biocomposites with and without coupling agent. As well, the physicochemical properties of biocomposites were monitored along the hydrothermal test by means of Scanning Electron Microscopy, Size Exclusion Chromatography and Differential Scanning Calorimetry. The addition of fibre induced higher water absorption capability and promoted physical degradation, as observed in the surface topography. During the processing of biocomposites and throughout the hydrothermal ageing, a reduction of molecular weight due to chain scission was found. As a consequence, a faster formation of crystalline domains in the PIA matrix occurred the higher the amount of fibre was, which acted as a nucleating agent. Higher crystallinity was considered as a barrier against the advance of penetrant and a reduction in the diffusion coefficient was shown. The addition of coupling agent presented a different influence depending on the composition, showing an inflection point around 20% of sisal fibre.
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| 42. |
- Gil-Castell, O., et al.
(författare)
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Impact of hydrothermal ageing on the thermal stability, morphology and viscoelastic performance of PLA/sisal biocomposites
- 2016
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Ingår i: Polymer degradation and stability. - : Elsevier. - 0141-3910 .- 1873-2321.
-
Tidskriftsartikel (refereegranskat)abstract
- The influence of the combined exposure to water and temperature on the behaviour of polylactide/sisal biocomposites coupled with maleic acid anhydride was assessed through accelerated hydrothermal ageing. The biocomposites were immersed in water at temperatures from 65 to 85 °C, between the glass transition and cold crystallisation of the PLA matrix. The results showed that the most influent factor for water absorption was the percentage of fibres, followed by the presence of coupling agent, whereas the effect of the temperature was not significant. Deep assessment was devoted to biocomposites subjected to hydrothermal ageing at 85 °C, since it represents the extreme degrading condition. The morphology and crystallinity of the biocomposites were evaluated by means of X-Ray diffraction (XRD) and field emission scanning electron microscopy (FE-SEM). The viscoelastic and thermal performance were assessed by means of dynamic mechanic thermal analysis (DMTA) and thermogravimetry (TGA). The presence of sisal generally diminished the thermal stability of the biocomposites, which was mitigated by the addition of the coupling agent. After composite preparation, the effectiveness of the sisal fibre was improved by the crystallisation of PLA around sisal, which increased the storage modulus and reduced the dampening factor. The presence of the coupling agent strengthened this effect. After hydrothermal ageing, crystallisation was promoted in all biocomposites therefore showing more fragile behaviour evidencing pores and cracks. However, the addition of coupling agent in the formulation of biocomposites contributed in all cases to minimise the effects of hydrothermal ageing.
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| 43. |
- Granstam, Elisabet, et al.
(författare)
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Reduced occurrence of severe visual impairment after introduction of anti-Vascular Endothelial Growth Factor in wet age-related macular degeneration : a population- and register-based study from northern Sweden
- 2016
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Ingår i: Acta Ophthalmologica. - : Wiley. - 1755-375X .- 1755-3768. ; 94:7, s. 646-651
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Tidskriftsartikel (refereegranskat)abstract
- PurposeTo study the occurrence of severe visual impairment (SVI) and treatment outcome at 12months in patients treated for wet age-related macular degeneration (AMD) by use of data from the Swedish Macula Register (SMR) and referrals to the regional low vision clinics in five northern counties. MethodsReferrals to low vision clinics during 2005, 2009 and 2013 and treatment outcome at 12months from the SMR database from 2008 until 2013 in patients >65years of age in five northern counties were included in the survey. ResultsThe rate of referral due to AMD was significantly reduced during the time period (-48%; p<0.001). At 12months, a significant slight mean improvement in logMAR visual acuity (VA) was observed (-0.01, SD 0.37; p<0.001) after a mean of 5.02.3 anti-vascular endothelial growth factor (VEGF)-injections were administered. Age and low baseline VA was associated with less favourable visual outcome (p<0.001). ConclusionReferral rate to low vision clinic is a valuable tool for estimating occurrence of SVI and fell between the years 2005 until 2013. Data from the SMR showed improvement in visual acuity on the whole, but also identified patients at high risk for developing SVI during anti-VEGF-treatment.
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| 44. |
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| 45. |
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| 46. |
- Holmgren, Kristina, 1977-, et al.
(författare)
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KNOGA. Fossilfri framdrift för tunga långväga godstransporter på väg : kostnadsfördelning och risker för olika aktörer (Executive summary)
- 2021
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Användningen av förnybar energi i transportsektorn behöver öka för att vi ska nå de svenska klimatmålen om minskade växthusgasutsläpp från inrikes transporterna med 70 procent till 2030, och nettonollutsläpp från samtliga sektorer till 2045. Ökningen av förnybara drivmedel behöver ske i alla segment och över hela fordonsflottan.Idag används främst diesel som drivmedel för tunga långväga godstransporter på väg men det finns alternativ för fossilfri framdrift. Denna studie har kvantifierat kostnadsstrukturer och analyserat riskfördelning mellan olika aktörer för fossilfria framdriftstekniker för tunga långväga godstransporter på väg och jämfört dem med alternativet att fortsätta använda diesel som drivmedel. Följande tekniker är inkluderade i studien: biobränslen (flytande och gasformiga), batterielektriska fordon (BEV), elvägar (tre olika tekniker), vätgasdrivna bränslecellsfordon (H2-FCEV) samt elektrobränslen. Beräkningar görs för år 2030 och 2045. Från de fem huvudkategorierna för fossilfri framdrift har ett antal representativa motortekniker, bränsleproduktionstekniker och råvaror valts ut för att analyseras i detalj. Detta har resulterat i ett trettiotal olika fossilfria alternativ till dagens användning av fossil diesel
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| 47. |
- Holmgren, Kristina, 1977-, et al.
(författare)
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KNOGA. Fossilfri framdrift för tunga långväga transporter på väg : Kostnadsfördelning och risker för olika aktörer
- 2021
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- För att nå de svenska klimatmålen om att minska växthusgasutsläppen från inrikes transporter (undantaget flyget) med 70% till 2030 och om att nå nettonollutsläpp för samtliga sektorer till 2045behöver användningen av förnybar energi i transportsektorn öka. Denna studie kvantifierar kostnadsstrukturer och analyserar riskfördelning mellan olika aktörer förfossilfria framdriftstekniker för tunga långväga godstransporter på väg. Följande tekniker är inkluderade i studien: biobränslen (flytande och gasformiga), elfordon med batterier (BEV), elvägar (tre olika tekniker), vätgasdrivna bränslecellsfordon samt elektrobränslen.denna studie görs också en jämförelse avseende de olika framdrivningsteknikernas växthusgas-utsläpp där bränsle/energianvändning, batteriproduktion (för tekniker med elektrisk framdrivning) och elvägsinfrastruktur inkluderas.Analyserna görs för två typer av lastbilar: HGV40 och HGV60. HGV40 är en tung lastbil med en tillåten bruttovikt om max 40 ton som används inom hela Europa. HGV60 är en lastbil med en tillåten bruttovikt om max 60 ton som står för merparten av transportarbetet med lastbil i Sverige, men som bara är tillåten i ett fåtal andra europeiska länder. Beräkningar görs för år 2030 och 2045.7Kostnader för de olika teknikalternativen redovisas i vad vi i denna studie har valt att kalla relativ mobilitetskostnad. Den relativa mobilitetskostnaden inkluderar: fordonens investeringskostnader, service och reparationer av fordon samt drivmedelskostnader. Drivmedelskostnaderna består av produktions-och distributionskostnader för drivmedel, där distributionskostnaderna inkluderar bådedirekta kostnader för distribution av drivmedel från produktionsanläggning till pump, samt investeringskostnader och underhåll för distributionsinfrastruktur (d.v.s. underhåll för elväg, ladd-infrastruktur eller tankstation). Genom att tydligt presentera de olika delarnas bidrag till den relativa mobilitetskostnaden erhålls en bild av hur kostnaderna för de olika framdrivningsteknikerna fördelar sig mellan fordonsinvestering, service och reparation av fordon, drivmedelsproduktions-kostnader och distributionsinfrastruktur. Alla kostnader beräknas utan skatter och avgifter. En ana-lys som visar påverkan på den relativa mobilitetskostnaden då man belastar alternativen med en CO2e-kostnad för bränsle/energianvändningen inkluderas också i studienStudiens sammanställning av hinder och risker för de olika alternativen baseras på kostnadsana-lysen, växthusgasjämförelsen och en litteraturgenomgång med fokus på ekonomiska, tekniska, infrastrukturrelaterade risker men också miljöpåverkan och tillgång på råvaror.
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| 48. |
- Hreggvidsson, Gudmundur O, et al.
(författare)
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Biocatalytic refining of polysaccharides from brown seaweeds
- 2020. - 1
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Ingår i: Sustainable Seaweed Technologies : Cultivation, Biorefinery and Applications - Cultivation, Biorefinery and Applications. - 9780128179437 - 9780128179444 ; , s. 447-504
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Bokkapitel (refereegranskat)abstract
- Brown macroalgae constitute 40% of the global production of seaweed, corresponding to approximately 10 million tonnes annually. Traditionally, seaweeds have been the source of hydrocolloids, food, and feed products. Due to possibilities for large-scale farming, brown macroalgae are a biomass with considerable potential for increased utilization. The main constituent polysaccharides, being alginate, cellulose, laminaran, and fucoidan, are the components of greatest importance for biorefinery usage. The polysaccharides can be extracted and applied for their physical or bioactive properties or used as a carbon source for microbial conversions to biofuels and commodity chemicals. The structural complexity and heterogeneous sugar composition of the polysaccharides make them a challenging biorefinery feedstock. These challenges can be overcome by the increasingly innovative biocatalytic tools, enzymes and microbes, that are being developed and that can be expected to open new opportunities and expand the product portfolio. However, there are still knowledge gaps, and further understanding is required on the molecular level of these interesting polymers, the tools, the refining possibilities, as well as transforming this knowledge to innovations—processes and products.
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| 49. |
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| 50. |
- Johnson, Randi K., et al.
(författare)
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Metabolite-related dietary patterns and the development of islet autoimmunity
- 2019
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Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 9:1
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Tidskriftsartikel (refereegranskat)abstract
- The role of diet in type 1 diabetes development is poorly understood. Metabolites, which reflect dietary response, may help elucidate this role. We explored metabolomics and lipidomics differences between 352 cases of islet autoimmunity (IA) and controls in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. We created dietary patterns reflecting pre-IA metabolite differences between groups and examined their association with IA. Secondary outcomes included IA cases positive for multiple autoantibodies (mAb+). The association of 853 plasma metabolites with outcomes was tested at seroconversion to IA, just prior to seroconversion, and during infancy. Key compounds in enriched metabolite sets were used to create dietary patterns reflecting metabolite composition, which were then tested for association with outcomes in the nested case-control subset and the full TEDDY cohort. Unsaturated phosphatidylcholines, sphingomyelins, phosphatidylethanolamines, glucosylceramides, and phospholipid ethers in infancy were inversely associated with mAb+ risk, while dicarboxylic acids were associated with an increased risk. An infancy dietary pattern representing higher levels of unsaturated phosphatidylcholines and phospholipid ethers, and lower sphingomyelins was protective for mAb+ in the nested case-control study only. Characterization of this high-risk infant metabolomics profile may help shape the future of early diagnosis or prevention efforts. © 2019, The Author(s).
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