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1.
  • Dahlin, Christer, 1959, et al. (author)
  • Apical peri-implantitis: possible predisposing factors, case reports, and surgical treatment suggestions.
  • 2009
  • In: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899. ; 11:3, s. 222-7
  • Journal article (peer-reviewed)abstract
    • BACKGROUND: Apical peri-implantitis is often diagnosed by clinical findings such as pain, redness, tenderness, swelling, and sometimes the presence of a fistulous tract. There are few theories about how such a lesion occurs. Hence, the current clinical treatment protocols are scanty. PURPOSE: The aim of this report was to evaluate and confer a more extended surgical protocol and to discuss possible predisposing factors for the development of retrograde peri-implantitis. MATERIALS AND METHODS: Two patients were extensively evaluated with regard to clinical signs, implant treatment, postoperative complications, and surgical treatment. The surgical protocol comprised debridement, with the additional removal of the apical portion of the affected implant. Postoperative checkup included clinical examination and radiographs. The follow-up period ranged from 1 to 3 years following surgical debridement. The possible predisposing factors are also discussed in the article. RESULTS: Both cases healed uneventfully with no further symptoms. Radiographs revealed complete bone fill into the resected area and continuous stable bone levels around the previously affected implants. CONCLUSIONS: It is concluded that recommendations for treatment of apical peri-implantitis are still minimal. In the present study, a surgical approach with resection of the apical portion of the affected implants in combination with debridement is suggested. Our experience was that partially resected oral implants remain osseointegrated and also function well clinically with a follow-up period up to 3 years.
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2.
  • Afshari, Mariam, 1989-, et al. (author)
  • Development of an oral health-related quality of life questionnaire on neurosensory disturbances after orthognathic surgery - a pilot study.
  • 2022
  • In: Acta odontologica Scandinavica. - : Informa UK Limited. - 1502-3850 .- 0001-6357. ; 80:8, s. 635-640
  • Journal article (peer-reviewed)abstract
    • Development of a new questionnaire, Oral Health-Related Quality of Life - Neurosensory Disturbances after Orthognathic Surgery (OHRQL-NDO), designed to measure the effects of neurosensory disturbance (NSD) on patients' oral health-related quality of life (OHRQL) and to evaluate reliability and validity of this questionnaire.A questionnaire including 11 items was constructed. Thirty patients with NSD affecting the lower lip and/or chin following orthognathic surgery were included. Convergent validity was assessed by comparing OHRQL-NDO with OHIP-14 and two global questions. Test-retest reliability was assessed by asking the patients to complete OHRQL-NDO at two different occasions with an interval of two to threeweeks.The internal consistency, measured with Cronbach's alpha, was 0.84. The test-retest reliability, measured with ICC, was 0.89 (95% CI 0.77-0.95). The correlation between the mean sum score for the OHRQL-NDO and the mean sum score for the OHIP-14 was r=0.75, using Pearson correlation coefficient. The correlations between the mean total score for the OHRQL-NDO and the global questions 1 and 2 were r=0.74 and r=0.72, respectively.The current instrument OHRQL-NDO is a promising test, but needs further development to better capture the different aspects of OHRQL. Further tests of the questionnaire must follow in other samples to finalize the instrument.
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3.
  • Dahlin, Christer, 1959, et al. (author)
  • One-Year Results of a Clinical and Radiological Prospective Multicenter Study on NEOSS® Dental Implants.
  • 2013
  • In: Clinical implant dentistry and related research. - : Wiley. - 1708-8208 .- 1523-0899.
  • Journal article (peer-reviewed)abstract
    • Background: NEOSS® (Neoss Ltd., Harrogate, UK) dental implant system was introduced on the clinical arena in 2003. It is important that novel implant systems are systematically evaluated in a multicenter setting. Purpose: The aim of this study was to follow a large number of consecutively treated patients, with NEOSS dental implant system, both clinically and radiographically. The current report constitutes the 1-year data of a planned 5-year study. Materials and Methods: The study included a total of 177 patients treated with 590 NEOSS implants at 13 clinics in Sweden. The material was composed of 72 males and 105 females treated for single, partial, and total edentulism. Clinical, radiographic, and subjective evaluations were performed. Results: Out of 590 implants, 13 early failures have been reported, corresponding to a 1-year cumulative survival rate (CSR) of 97.8%. Evaluation of function and esthetics at the 1-year visit resulted in 100% success for function and 98% success for the esthetic outcome. The mean marginal bone loss was 0.6mm (SD 1.1) after 1year in clinical function. No adverse effects of the NEOSS dental implants were reported, and complications were few and similar to those reported for implant treatment in general. Conclusion: The CSR in the present study was 97.8%. No adverse effects of the NEOSS implants were reported, and complications during the study period were few and similar to those reported to for other well-documented implants system. Based on the present data, we conclude that NEOSS dental implant is a safe and predictable implant system. However, the high number of dropouts in the radiological evaluation must be considered when interpreting the data.
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4.
  • Dasmah, Amir, et al. (author)
  • Integration of fluoridated implants in onlay autogenous bone grafts - An experimental study in the rabbit tibia.
  • 2014
  • In: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. - : Elsevier BV. - 1878-4119 .- 1010-5182. ; 42:6, s. 796-800
  • Journal article (peer-reviewed)abstract
    • Bone augmentation before treatment with endosseous implants is a common procedure for rehabilitation of the edentulous jaw. Both machined and surface modified implants have been used in one-stage and two-stage surgery protocols with varying results and survival rates. The influence of surface modification on the integration of implants has been documented in both non-grafted and grafted bone. The aim of this study was to compare the integration and stability of surface modified fluoridated vs. machined implants when placed simultaneously with an onlay bone graft.
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5.
  • Hilon, Jack, et al. (author)
  • Phenotype of Crohn's disease according to the Montreal classification in relation to dental health status.
  • 2022
  • In: Scandinavian journal of gastroenterology. - : Informa UK Limited. - 1502-7708 .- 0036-5521. ; 57:2, s. 183-189
  • Journal article (peer-reviewed)abstract
    • The relationship between oral health and Crohn's disease is uncertain. Previous studies have yielded contradictory results, reflecting perhaps the different phenotypes of the disease. The aim of the present study was to describe and analyse the dental status of a group of patients with Crohn's disease (CD), considering the positions of the inflammatory loci and disease phenotype.In total, 47 patients with Crohn's disease (18 males and 30 females; mean age. 48.7years; range, 23-61years) were consecutively recruited to this study. Interviews and clinical examinations were performed to assess dental status, medication, smoking history, heredity of inflammatory bowel disease (IBD), duration of disease, oral mucosal manifestations of Crohn's disease. Furthermore, data on subjective health assessments and family status, along with medical histories from the patients were obtained through questionnaires. The disease phenotypes were assessed and classified according to the Montreal classification. The data on oral health status were first correlated with the Montreal classifications of IBD, and, thereafter, all the collected data were included in a multivariate generalised linear model.The dental status of the patients was comparable to that of the Swedish average. No statistically significant associations were found between oral status and the different CD phenotypes. However, within the Montreal classification, there were significantly fewer teeth in those patients with perianal lesions than in those without such lesions, and there was a significant correlation between deeper pocket depth and problems with strictures and penetrations. No significant differences (p=.074) between the patients with CD (N=47) and controls (N=38) were found regarding the presence of oral mucosal lesions.Dental health may be adversely affected in severe cases of CD whereas most of the remaining patients with CD appear to have a level of dental health that is comparable to that in the general population.
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6.
  • Hossein, Kashani, et al. (author)
  • Influence of different prophylactic antibiotic regimens on implant survival rate: A retrospective clinical study
  • 2005
  • In: CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH. - : Wiley. - 1523-0899 .- 1708-8208. ; 7:1, s. 32-35
  • Journal article (peer-reviewed)abstract
    • Background: The routine use of antibiotics in oral implant treatment seems to be widespread. The pre- or postoperative use of antibiotics in conjunction with implant surgery and its correlation with failure and success rates are poorly documented in the literature. The debate regarding overprescription of antibiotics raises the need for a critical evaluation of proper antibiotic coverage in association with implant treatment. Purpose: The purpose of this study was to compare the implant survival rate following a 1-day single-dose preoperative antibiotic regimen with that following a 1-week postoperative antibiotic protocol. Materials and Methods: The study included 868 consecutively treated patients. A total of 3,021 implants were placed. The population was split into two categories, either receiving a 1-day single-dose administration only, or a 1-week postoperative administration of antibiotics. Healing was evaluated at second-stage surgery (6 months for the upper jaw, 3 months for the lower jaw). Failure was defined as removal of implants because of non-osseointegration. Statistical analyses were performed with analysis of variance and the Scheffe test, with a significance level of 5% for comparison of data. Results: No significant differences with regard to complications and implant survival were found in the study. Conclusion: Based on the present data, a more restrictive regimen consisting of a 1-day dose of prophylactic antibiotic in conjunction with routine implant procedures is recommended.
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7.
  • Hossein, Kashani, et al. (author)
  • Sinus-lift by Use of Hemihydrate-Calcium Sulphate: A Prospective Clinical, Radiographical, Histological Study of Implant Integration in the Posterior Maxilla
  • 2017
  • In: EC Dental Science. ; 15:6, s. 240-249
  • Journal article (peer-reviewed)abstract
    • The objective of this study was to evaluate implant survival in reconstructed bone after the use of a synthetic bone substitute material (Calcium Sulphate). Clinical, radiological and histological parameters were studied in 25 patients. Unilateral and bilateral sinus augmentation was performed. An 80% + 20% mixed alpha hemihydrate Calcium Sulphate with autograph bone respectively was applied into the maxillary sinus. After six months, dental implants were installed. Prior to implant installation, all patients underwent a CT examination. In total 91 implants were inserted in all 25 subjects, 74 of these in augmented bone. Additionally, two micro-implants were installed bilaterally in 8 patients. After four months of healing, a third operation was performed to insert the healing abutments into the implants. Simultaneously, the micro-implants were retrieved for histological analysis. Implant stability was assessed through resonance frequency analysis at installation and at abutment connection. The pattern of bone formation in the experimental sites was investigated using histomorphometric measurements. Implant survival rate was 96,8% at abutment connection. The mean ISQ value at implant placement was 65.8 and at abutment connection 66,5. The mean bone to implant contact was 27,0%.
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8.
  • Jonasson, Grethe, 1945, et al. (author)
  • Crohn’s Disease and Fracture Risk Assessment with FRAX
  • 2019
  • In: Crohn's & Colitis 360. - : Oxford University Press (OUP). - 2631-827X. ; 1:2
  • Journal article (peer-reviewed)abstract
    • Background Studies are inconsistent whether people with Crohn disease (CD) have an increased fracture risk. This study showed that patients with Crohn’s disease (CD) had a higher ten year probability of fracture, assessed by the fracture assessment tool FRAX, and more fractures, but the proportion of CD patients with a fracture was not significantly higher than that of controls. Methods Forty-nine CD and 49 controls participated. All 98 completed a health questionnaire. A score with the fracture assessment tool FRAX > 15% was considered risk factor for fracture. Results Mean FRAX score for 49 CD was 10.1 ± 10.3% and for 49 controls 5.0 ± 3.9% (P = 0.002). The variables correlated with fracture were being female (P = 0.04) and having a fractured mother (P = 0.002). Conclusion The CD group had significantly higher FRAX scores and more fractures, but the proportion of CD subjects with a fracture was not significantly higher than that of controls.
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9.
  • Jonasson, Grethe, 1945, et al. (author)
  • Mandibular trabecular bone structure in adults with Crohn's disease.
  • 2014
  • In: Clinical oral investigations. - : Springer Science and Business Media LLC. - 1436-3771 .- 1432-6981. ; 18:2, s. 423-428
  • Journal article (peer-reviewed)abstract
    • OBJECTIVES: Crohn's disease (CD) is associated with reduced bone mineral density. The main objective of the present study was to assess the mandibular trabecular bone quality and to compare our findings with those among sex- and age-matched controls. Furthermore, background variables known to be significant for bone density were compared. MATERIALS AND METHODS: Intraoral radiographs of 49 Crohn's patients (23-61years old) and 49 age- and sex-matched controls were evaluated. Mandibular trabecular pattern was classified as either sparse, mixed dense plus sparse, or dense. Furthermore, two computer-based methods analyzed the transitions from trabecula to intertrabecular spaces and the size and number of these spaces. Differences in continuous background variables were tested with Student's two-sample t test and ordinal variables with Mann-Whitney U test or Kruskal-Wallis nonparametric tests. RESULTS: All three methods to evaluate bone structure seen on dental radiographs showed significantly sparser trabeculation in Crohn's patients than in the control group. The Crohn's patients were heavier, more often smokers, and more frequently had mothers who developed fragility fractures. Furthermore, the Crohn's patients, especially smokers, had a significantly higher fracture rate than the matched control group but no significant relationship was found between trabeculation pattern and fracture. CONCLUSIONS: The results of this investigations indicated that trabecular bone is significantly sparser in subjects with Crohn's disease compared to a matched control group. CLINICAL RELEVANCE: An early identification of CD patients with sparse trabeculation and appropriate advice concerning nutrition and exercise may lead to less fractures and medication in the future.
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10.
  • Kahnberg, Karl-Erik, 1941, et al. (author)
  • Sagittal split advancement osteotomy: Comparison of the tendency to relapse after two different methods of rigid fixation.
  • 2007
  • In: Scandinavian journal of plastic and reconstructive surgery and hand surgery / Nordisk plastikkirurgisk forening [and] Nordisk klubb for handkirurgi. - : Informa UK Limited. - 0284-4311. ; 41:4, s. 167-72
  • Journal article (peer-reviewed)abstract
    • Mandibular advancement was studied in 32 patients with mandibular retrognathia in whom the only intervention was in the mandible. Fifteen patients were treated with fixation by lag screws and 17 with monocortical miniplates. Lateral radiographs were taken preoperatively, postoperatively, 2 months postoperatively, and 1.5 years postoperatively, and mandibular movement analysed. All patients healed uneventfully. Cephalometric analysis of lateral radiographs showed no significant differences between the two groups in skeletal relapse during any of the control periods up to 18 months. Mandibular advancement for treatment of mandibular retrognathia using rigid fixation with either lag screws or miniplates was reproducable with only minor skeletal relapse.
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12.
  • Kashani, Amir Hossein Navidi, et al. (author)
  • Morphology, mechanical properties, and oxidation behavior of stoichiometric Ti0.33-xAlxB0.67 coatings (x=0.04, 0.15, 0.21, and 0.28)
  • 2024
  • In: Acta Materialia. - : Elsevier. - 1359-6454 .- 1873-2453. ; 270
  • Journal article (peer-reviewed)abstract
    • Stoichiometric Ti0.33-xAlxB0.67 coatings with x = 0.04, 0.15, 0.21, and 0.28 were synthesized by magnetron sputtering and characterized regarding phase formation, mechanical properties, and oxidation behavior. By increasing the Al concentration from 4 to 28 at.%, the measured elastic modulus (496±19 GPa) and unit cell volume (25.646 Å3 ) decreased by 33 and 0.8 %, respectively. The Al concentration induced changes in measured elastic modulus and unit cell volume are in very good agreement with ab initio predictions, as the maximum deviations between experiment and theory, observed here, are 12 and 1.1 %, respectively. The corresponding hardness values decreased by 45 % from 22±1 to 12±1 GPa. The oxidation experiments were performed in ambient air at 700, 800, and 900 °C for 1, 4, and 8 h. Analysis by scanning transmission electron microscopy (STEM) revealed a bimodal, strongly Al concentration-dependent oxidation behavior where films containing ≤15 at.% of Al form a porous, non-passivating crystalline oxide scale containing Ti -rich as well as Al -rich oxide regions, while the formation of a passivating, dense, X-ray amorphous oxide scale was observed for films containing ≥ 21 at.% of Al. Coincident with the passive scale formation for Al concentrations ≥ 21 at.%, the elastic modulus decreases by ≥ 32.6 % compared to TiB2 and can be rationalized based on Al concentration induced bond weakening as revealed by the concomitant cohesive energy reduction of ≥ 22 %.
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13.
  • Kashani, Amir Hossein Navidi, et al. (author)
  • Synthesis and oxidation behavior of Ti0.35Al0.65By (y=1.7-2.4) coatings
  • 2022
  • In: Surface & Coatings Technology. - : Elsevier. - 0257-8972 .- 1879-3347. ; 442
  • Journal article (peer-reviewed)abstract
    • The effect of B concentration on phase formation and oxidation resistance of (Ti0.35Al0.65)By coatings with y = 1.7, 2.0, 2.4 was investigated. Elemental B targets in radio frequency mode and a compound Ti0.4Al0.6 target in direct current mode were sputtered. The B concentration was varied systematically by adjusting the applied power to the respective magnetrons, while keeping the power supplied to the magnetron with the Ti0.4Al0.6 target constant. Measured lattice parameters and elastic properties are consistent with ab initio predictions. The oxidation resistance at 700 degrees C in air for up to 8 h was compared to a cathodic arc evaporated (Ti0.37Al0.63)0.49N0.51 coating with an Al/Ti ratio of 1.69 +/- 0.20 which is very similar to 1.84 +/- 0.40 for the boride coatings. Scanning transmission electron microscopy imaging revealed oxide scale thicknesses of 39 +/- 7 and 101 +/- 25 nm for (Ti0.35Al0.65)B2.0 and (Ti0.37Al0.63)0.49N0.51 after 8 h, respectively. Hence, the close to stoichiometric diboride outperforms the nitride coating. This behavior can be understood based on composition and structure analysis of the oxide scales: While the protective layer on the diboride is primarily composed of Al and O, the porous oxide layer on the nitride coating contains Ti, Al and O.
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14.
  • Kashani, Hossein, et al. (author)
  • A randomized double-blind comparative study of Biolight light therapy following surgical extraction of impacted lower third molars.
  • 2007
  • In: Swedish dental journal. - 0347-9994. ; 31:4, s. 165-70
  • Journal article (peer-reviewed)abstract
    • Monochromatic light has been used in many studies and indicated that phototherapy might be effective in the treatment of pain relief. The aim of this investigation was to evaluate the efficacy of monochromatic light phototherapy on patients who had undergone impacted third molar surgery. Sixty adult patients were included in the study. The patients were divided into 2 groups; the Biolight therapy group and the placebo therapy group. All the subjects received phototherapy 6 minutes preoperative and 10 minutes postoperative. They were examined 3 and 7 days after surgery to evaluate postoperative pain and wound healing. One patient was excluded from the study due to extraction of the third molar in maxilla. All the patients received a questionnaire to answer regarding pain and the number of pain killers consumed. The results from this study showed that Phototherapy using monochromatic light Biolight therapy had no significant differences compared to the placebo group.
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15.
  • Kashani, Hossein, et al. (author)
  • Effect of NaF-, SnF2-, and chlorhexidine-impregnated birch toothpicks on mutans streptococci and pH in approximal dental plaque.
  • 1998
  • In: Acta odontologica Scandinavica. - 0001-6357. ; 56:4, s. 197-201
  • Journal article (peer-reviewed)abstract
    • The antimicrobial effect of birch toothpicks impregnated with 4% NaF, 8% SnF2, or 2% chlorhexidine was studied both in vitro and in vivo. A non-impregnated toothpick served as a control. In vitro, suspensions of Streptococcus mutans were exposed to the various toothpicks for 20 min and then cultured on blood agar. The results of this susceptibility test revealed the following ranking order with respect to inhibition: chlorhexidine > SnF2 > NaF and non-impregnated; with significant differences in colony-forming units (CFU) between these three groups. In vivo, 12 individuals used the 4 types of toothpick 3 times a day for 5 days in a procedure with a crossover design. Saliva and approximal plaque samples were collected at baseline and on various occasions up to 23 days after the treatment. At the same time, plaque-pH was measured at approximal sites 10 min after rinsing with 10% sucrose. The results of these in vivo experiments revealed lower proportions of mutans streptococci after using all four types of toothpick, but the reduction was significant only after 2 days for the toothpicks impregnated with SnF2 and chlorhexidine (P< 0.05). On the sampling occasions 9 and 23 days after the treatment, the mutans streptococci were more or less back to baseline levels again. In saliva no significant differences in the number of mutans streptococci were found either within or between the four treatments. No significant differences were found regarding decline in the plaque-pH between the NaF-, SnF2-, chlorhexidine-, and non-impregnated toothpicks on any of the sampling occasions.
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16.
  • Kashani, Hossein, et al. (author)
  • Effect of toothpicks with and without fluoride on De- and remineralization of enamel and dentine in situ.
  • 1998
  • In: Caries research. - 0008-6568. ; 32:6, s. 422-7
  • Journal article (peer-reviewed)abstract
    • The aim of this investigation was to study the effect of the interproximal use of fluoride (F)-impregnated and non-impregnated birch toothpicks on the degree of de- and remineralization of enamel and dentine in situ. Ten volunteers with complete dentures in the upper jaw participated. Each subject had four specimens: (1) sound enamel, (2) demineralized enamel, (3) sound dentine and (4) demineralized dentine; placed pairwise at two approximal sites (15/16 and 25/26) of the maxillary prosthesis. The study involved three test periods (A, B and C), each lasting 4 weeks. In A, the subjects used F toothpicks (impregnated in 4% NaF) and, in B, nonimpregnated toothpicks 3 times daily. During period C, no toothpicks were used. Dentifrice or other F-containing products were not allowed during the 4-week periods. Transversal microradiography was used to determine lesion depth (ld) and mineral loss (DeltaZ). The results revealed that all the sound samples lost mineral during the three experimental periods; DeltaZ for both enamel and dentine was less for A and B compared with C (p<0.01) and less for A compared with B and C for dentine (p<0.05, p<0.01). The demineralized samples also lost mineral, apart from dentine, during periods A and B, i.e. when F-impregnated and non-impregnated toothpicks were used; ld for enamel and DeltaZ for dentine were less for A compared with C (p<0.05). Four weeks' use of toothpicks, especially F-impregnated toothpicks, thus reduces the demineralization of enamel and dentine at approximal sites in situ.
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17.
  • Kashani, Hossein, et al. (author)
  • Fluoride concentration in the approximal area after using toothpicks and other fluoride-containing products.
  • 1998
  • In: European journal of oral sciences. - 0909-8836. ; 106:1, s. 564-70
  • Journal article (peer-reviewed)abstract
    • The aim of this work was to study the fluoride (F) concentration in the approximal area after using toothpicks and other F-containing products. The exposure time was standardised to 2 min. 24 subjects participated, divided into 4 groups, with 6 individuals per group. In 3 of the groups, the following 4 products were compared: (1) a toothpick impregnated in 4% NaF; (2) a dentifrice containing 0.32% NaF; (3) a mouthrinse solution containing 0.025% NaF; (4) a tablet containing 0.55 mg NaF. In the 4th group, 3 commercial F toothpicks and 2 F dental flosses were compared. In all 4 groups, the F concentration was determined up to 60 min at 4 approximal sites. On each sampling occasion, 3 triangle-shaped paper points were used, absorbing 3 x 1 microl. In general, the toothpick gave similar or somewhat higher F concentrations in the approximal area than the dentifrice, mouthrinse solution and tablet. Comparing the various commercial toothpicks and dental flosses, 2 of the toothpicks gave higher approximal F concentrations than the other 3 products. When comparing the series in which the very first sample was collected from 2-20 min after the F treatment, it was found that the sampling procedure itself reduced the subsequent approximal F concentration. The main conclusion from this study is that an F-impregnated toothpick is a promising vehicle for delivery of fluoride to the approximal area.
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18.
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19.
  • Kashani, Hossein, et al. (author)
  • Influence of a single preoperative dose of antibiotics on the early implant failure rate. A randomized clinical trial
  • 2019
  • In: Clinical Implant Dentistry and Related Research. - : Wiley. - 1523-0899 .- 1708-8208. ; 21:2, s. 278-283
  • Journal article (peer-reviewed)abstract
    • Background The use of a preoperative single dose of antibiotics as routine in conjunction with implant surgery is controversial, in light of the unclear effect on early implant failure rate and risk for development of resistant bacterial strains. Purpose This randomized clinical trial compared the early implant failure rates in two different patient cohorts: One group receiving a single dose of preoperative antibiotics (AB group) and one group receiving no antibiotics, prior to implant surgery (noAB group). Materials and Methods Patients were referred for treatment at four specialist clinics in the county council of West Sweden, Vastra Gotaland and randomly assigned into one of the two groups. A total of 447 patients received 963 implants were included in the study. Of these, 223 patients (535 implants) belonged to the AB-group and 224 patients (428 implants) to the noAB-group. Four commercial implant brands were utilized, albeit one system was only represented with four implants. The outcome was evaluated after 4 months using either a one-stage or two-stage procedure. The surgical procedures were performed by experienced implant surgeons and the surgical protocol for implant placement follows standard. Failure was defined as removal of an implant for any reason. The study outcomes were statistically analyzed to evaluate the differences between the two groups. Results Twelve implants failed in 11 patients for the AB group, and 32 implants failed in 29 patients for the noAB group. Preoperative antibiotics, AB group, had significantly (P < 0.0011) lower implant failure 2.2% compared to 7.5% in the noAB group analyzed on implant level adjusted for dependence within patients, OR = 0.30, 95% confidence interval (0.14-0.62). Conclusion Administration of a single dose of antibiotics in conjunction with implant placement surgery resulted in a statistically significant lower early implant failure rate compared to when no antibiotics were used.
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20.
  • Kashani, Hossein, et al. (author)
  • Osteotomies in Orthognathic Surgery
  • 2016
  • In: A Textbook of Advanced Oral and Maxillofacial Surgery, Vol. 3. Mohammad Hosein Kalantar Motamedi (red.). - : INTECH. - 9789535125914 ; , s. 617-649
  • Book chapter (peer-reviewed)
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21.
  • Kashani, Hossein (author)
  • Studies on fluoridated toothpicks.
  • 1998
  • In: Swedish dental journal. Supplement. - 0348-6672. ; 126, s. 1-48
  • Journal article (peer-reviewed)abstract
    • The aim of this thesis was to evaluate the wooden toothpick as a vehicle for the delivery of fluoride to the approximal area. After two minutes use in vivo, the release of fluoride from the pointed section of a toothpick impregnated in 4% NaF was estimated to 0.15 mg. Toothpicks produced similar or somewhat higher fluoride concentrations in the approximal area compared with other fluoride-containing products, like dentifrice, mouthrinse solution and tablet. The mean fluoride concentration in an approximal area treated for two minutes with a toothpick impregnated in 4% NaF was around 11 mM/l. Toothpicks impregnated in 4% NaF, 8% SnF2 or 2% chlorhexidine had an effect on the proportion of mutans streptococci and on the decline of pH in dental plaque, but it was small and only of short duration. The recolonization of mutans streptococci was, however, slower after using the SnF2- and chlorhexidine-impregnated toothpicks than after using the NaF- and non-impregnated toothpicks. The effect of fluoridated toothpicks on the degree of de- and remineralization of enamel and dentine was measured using transversal microradiography in an in situ study. Four weeks' use of toothpicks, especially of NaF-impregnated toothpicks, reduced the degree of demineralization of enamel and dentine at approximal sites. Secondary ion mass spectrometry was also used to determine the fluoride content in the outer surface of dentine, which increased more than 10 times after using fluoride toothpicks compared with non-impregnated toothpicks. In a second in situ study, 4% NaF-, 2% chlorhexidine- and non-impregnated toothpicks had a similar effect on sound and demineralized enamel and on demineralized dentine. However, the NaF toothpicks were superior in terms of their effect on sound dentine. The effect on mutans streptococci and plaque-pH, on the other hand, was the same for all three types of toothpicks. The main conclusion from this thesis is that the wooden toothpick is a suitable vehicle for the delivery of fluoride to the approximal area.
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22.
  • Kashani, Hossein, et al. (author)
  • Uptake and release of fluoride from birch and lime toothpicks.
  • 1995
  • In: European journal of oral sciences. - 0909-8836. ; 103:2 ( Pt 1), s. 112-5
  • Journal article (peer-reviewed)abstract
    • Birch and lime toothpicks were impregnated in a 4% sodium fluoride (NaF) solution for different periods of time, viz. 30 s, 30 min and 3 d. After impregnation for 30 min, an average of 4.1 mg NaF per birch toothpick was taken up. The corresponding value for lime toothpicks was 5.1 mg. About 60% of the fluoride (F) was released within 1 h in vitro when the toothpicks were kept in water. In vivo, the concentration of F was determined in whole saliva from five adults during 30 min after using birch toothpicks immersed in a 4% NaF solution. After 2 min, the mean salivary F concentration was 2.7 mM. Impregnation of birch toothpicks in 1, 2 or 3% NaF resulted in lower F concentrations both in vitro and in vivo, with a clear dose-response effect. When comparing the use of a 4% NaF impregnated birch toothpick, a mouthrinse with 10 ml of 0.025% NaF, sucking on a F tablet containing 0.55 mg NaF, and toothbrushing with 1 g of an 0.068% F (as NaF) dentifrice--all procedures carried out in the mouth during 2 min--the highest concentration of F in saliva was obtained after using the fluoridated toothpick. Thus, NaF impregnated birch and lime toothpicks show a quick release of F in vitro as well as in vivo and may be suitable as home care products for prevention of dental caries.
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23.
  • Petersson, L G, et al. (author)
  • In vitro and in vivo studies of an NaF impregnated toothpick.
  • 1994
  • In: Swedish dental journal. - 0347-9994. ; 18:3, s. 69-73
  • Journal article (peer-reviewed)abstract
    • Fluoridated toothpicks (John O. Butler Co.), containing an average of 0.80 mg F as NaF, demonstrated a quick F release in vitro after 1 min immersion in distilled water (0.13 mg; 16%). Continued F release was found after 5 (0.22 mg; 28%) and 60 min (0.35 mg; 44%) and 24 hr (0.55 mg; 69%). In addition, F concentrations were measured in whole saliva of 10 adults before and after 1 min use of an F toothpick and after sucking on an 0.25 mg F tablet (Fludent). Baseline F concentrations of about 1 microM/L increased to 35 microM/L after using the toothpick. In comparison, the F tablet gave a mean salivary F concentration of 71 microM/L. The F levels in saliva after 1 hr were for the F toothpick 3 microM/L and for the F tablet 8 microM/L. Thus, F impregnated toothpick seems to be an interesting vehicle for F release in the oral cavity and merits further studies from a cariostatic point of view.
  •  
24.
  • Rasmusson, Lars, 1962, et al. (author)
  • Orthognathic Surgery (Chapter 25a)
  • 2021
  • In: Nordic Textbook of Oral and Maxillofacial Surgery. - Copenhagen : Munksgaard. - 9788762820128
  • Book chapter (other academic/artistic)
  •  
25.
  • Silva, Ingrid, et al. (author)
  • Quality of life in patients undergoing orthognathic surgery - A two-centered Swedish study
  • 2016
  • In: Journal of Cranio-Maxillofacial Surgery. - : Elsevier BV. - 1010-5182 .- 1878-4119. ; 44:8, s. 973-978
  • Journal article (peer-reviewed)abstract
    • Aim: Surgical corrections of dentofacial deformities have both physical and psychological impact on quality of life (QoL). The objectives of the present study were to evaluate the impact of oral health related problems on QoL before and after a combination of orthodontic treatment and orthognathic surgery. Additionally, the study aimed to identify correlations between different dentofacial patterns and possible improvements due to treatment. Material and methods: In a prospective study, we evaluated fifty patients before start of treatment, 6 weeks and 6 months postoperatively. The questionnaires used were: OHIP-14 (Short Form Oral Health Impact Profile), a condition-specific QOL approach (Orthognathic Quality of Life Questionnaires; OQLQ) and a social-demographic questionnaire. Results: There was a statistically significant improvement in the OHIP domains from baseline to 6 months follow-up and for the OQLQ the improvement was significant both at 6 weeks and 6 months in relation to the baseline data. Conclusion: Significant improvement of quality of life over time is proved by both OHIP-14 and OQLQ in the present study. Socio-demographic and holistic considerations are important when evaluating treatment outcome after combined orthodontic and orthognatic surgery. However, longer follow-up would be beneficial. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
  •  
26.
  • Widar, Fredrik, et al. (author)
  • A retrospective evaluation of iatrogenic dental root damage with predrilled vs drill-free bone anchor screws for intermaxillary fixation.
  • 2012
  • In: Dental traumatology. - : Wiley. - 1600-9657 .- 1600-4469. ; 28:2, s. 127-131
  • Journal article (peer-reviewed)abstract
    • Abstract- Aims:The aim of this study was to retrospectively evaluate iatrogenic dental root damage, caused by two different techniques that utilized bone anchor screws, for intermaxillary fixation (IMF) in orofacial trauma. Materials and methods:The techniques used included either predrilled or drill-free bone anchor screws. A total of 123 patients who required IMF were evaluated (97 men and 26 women). Sixty-four patients were treated in the predrilled group, and 59 patients were treated in the drill-free group. The data were collected over an 8-year period and were analyzed using crosstabs and Fisher's exact test. Results:Injuries to dental roots were found only in the predrilled group. Twenty-nine patients (45.3%) were injured at the time of surgery. One year after surgery, 10 patients (15.6%) had permanently injured dental roots. There was a significant difference in injury rates between the predrilled and drill-free groups 1year after surgery (P<0.001). Conclusion:There is an increased potential risk of iatrogenic injury and permanent damage to the dental roots when a technique that involves predrilled holes for bone anchor screws is used.
  •  
27.
  • Widar, Fredrik, et al. (author)
  • Incidence and risk factors predisposing plate removal following orthognathic surgery
  • 2017
  • In: Oral Surgery Oral Medicine Oral Pathology Oral Radiology. - : Elsevier BV. - 2212-4403. ; 124:3, s. 231-239
  • Journal article (peer-reviewed)abstract
    • Objective. The aim of this study was to investigate the incidence and reasons for titanium fixation plate removal following orthognathic surgery, identify risk factors predisposing removal, and explore if discomfort was reduced postoperatively. Study Design. Medical records of 404 consecutive cases were retrospectively reviewed. All patients received a questionnaire for follow-up, and 323 patients answered the questionnaire, thus forming the sample group. Results. Of all the responding patients, 15% had plates removed, and 92% of these patients experienced relief from discomfort after removal of the plates. Infection was the most common reason for plate removal (10%). Smoking (hazard ratio 2.74) and surgery performed in the mandible (hazard ratio 2.40) increased the need for plate removal. For each plate added in the mandible, the risk for removal increased by 34%. Conclusions. Smoking, osteotomies, and additional numbers of plates in the mandible resulted in a higher incidence of plate removal. Most of the patients experienced relief from discomfort after plate removal.
  •  
28.
  • Widar, Fredrik, et al. (author)
  • The effects of steroids in preventing facial oedema, pain, and neurosensory disturbances after bilateral sagittal split osteotomy: a randomized controlled trial.
  • 2015
  • In: International journal of oral and maxillofacial surgery. - : Elsevier BV. - 1399-0020 .- 0901-5027. ; 44:2, s. 252-258
  • Journal article (peer-reviewed)abstract
    • A randomized, prospective, controlled trial was conducted to determine the efficacy of single and repeated betamethasone doses on facial oedema, pain, and neurosensory disturbances after bilateral sagittal split osteotomy. Thirty-seven patients (mean age 23.62 years, range 17-62 years) with either mandibular prognathism or retrognathism were enrolled consecutively into the study and divided into three groups: control (n=12), repeated dose 4+8+4mg betamethasone (n=14), single dose 16mg betamethasone (n=11). The intake of diclofenac and paracetamol was assessed individually. Measurements of facial oedema, pain, and sensitivity in the lower lip/chin were obtained 1 day, 7 days, 2 months, and 6 months postoperatively. Furthermore, we investigated the possible influences of gender, age, total operating time, amount of bleeding, postoperative hospitalization, and advancement versus setback of the mandible. A significant difference (P=0.017) was observed in percentage change between the two test groups and the control group regarding facial oedema (1 day postoperatively). Less bleeding was associated with improved pain recovery over time (P=0.043). Patients who required higher postoperative dosages of analgesics due to pain had significantly delayed recovery of the inferior alveolar nerve at 6 months postoperatively (P<0.001). Betamethasone did not reduce neurosensory disturbances over time.
  •  
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