| 1. |
- Andreasson, Anna, et al.
(författare)
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An Increasing Incidence of Upper Gastrointestinal Disorders Over 23 Years : A Prospective Population-Based Study in Sweden
- 2021
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Ingår i: American Journal of Gastroenterology. - : Ovid Technologies (Wolters Kluwer Health). - 0002-9270 .- 1572-0241. ; 116:1, s. 210-213
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: We hypothesized that the prevalence of functional dyspepsia and gastroesophageal reflux disease in the community may be increasing.METHODS: Randomly selected adults were surveyed on 4 occasions: 1988 (n = 1,151, 21–79 years, response rate [rr] = 90%), 1989 (n = 1,097, 22–80 years, rr = 87%), 1995 (n = 1,139, 20–85 years, rr = 76%), and 2011 (n = 1,175, 20–93 years, rr = 63%).RESULTS: In functional dyspepsia, the odds of postprandial distress syndrome tripled over 23 years' follow-up (odds ratio [OR]: 3.55; 95% confidence interval [CI]: 2.60–4.84, mixed-effect regression analysis), whereas a small decrease in epigastric pain syndrome was observed (OR: 0.65, 95% CI: 0.42–1.00). The odds of reporting gastroesophageal reflux disease doubled (OR: 2.02; 95% CI: 1.50–2.73).DISCUSSION: The underlying mechanisms behind the increase in postprandial distress syndrome and gastroesophageal reflux disease remain to be determined.
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| 2. |
- Forsberg, Anna, et al.
(författare)
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Colonoscopy findings in high-risk individuals compared to an average-risk control population
- 2015
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Ingår i: Scandinavian Journal of Gastroenterology. - : Informa UK Limited. - 0036-5521 .- 1502-7708. ; 50:7, s. 866-874
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Tidskriftsartikel (refereegranskat)abstract
- Background and aims: There is clear evidence of reduced morbidity and mortality from regular colonoscopy programs in patients with Lynch syndrome (LS). Today, also individuals with empirically increased risks of colorectal cancer (CRC) are offered colonoscopic surveillance. The aim was to compare the findings at the first screening colonoscopy in LS carriers, and individuals with an increased risk of bowel cancer due to family history of CRC with a control population. Methods: Altogether 1397 individuals with an increased risk for CRC were divided in four risk groups: one with LS carriers and three groups with individuals with different family history of CRC. The findings were compared between the different risk groups and a control group consisting of 745 individuals from a control population who took part in a population-based colonoscopy study. Results: In LS, 30% of the individuals had adenomas and 10% advanced adenomas. The corresponding figures in the other risk groups were 14-24% and 4-7%, compared with 10% and 3% in the control group. The relative risk of having adenomas and advanced adenomas was, compared to controls, significantly higher for all risk groups except the group with the lowest risk. Age was a strong predictor for adenomas and advanced adenomas in both risk individuals and controls. Conclusions: Individuals with a family history of CRC have a high prevalence and cumulative risk of adenomas and advanced adenomas, and screening is motivated also in this risk group.
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| 3. |
- Forsberg, Anna M., et al.
(författare)
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Prevalence of colonic neoplasia and advanced lesions in the normal population : a prospective population-based colonoscopy study
- 2012
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Ingår i: Scandinavian journal of gastroenterology. - : Informa UK Limited. - 1502-7708 .- 0036-5521. ; 47:2, s. 184-90
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Tidskriftsartikel (refereegranskat)abstract
- Objective. There are few prospective studies of the prevalence of colonic neoplasia in the normal population. In order to properly evaluate screening-protocols for colorectal cancer in risk groups (e.g., older subjects or those with a family history), it is essential to know the prevalence of adenomas and cancer in the normal population. Methods. A prospective population-based colonoscopy study on 745 individuals born in Sweden aged 19-70 years was conducted (mean age 51.1 years). All polyps seen were retrieved and examined. Results. Out of the 745 individuals 27% had polyps, regardless of kind. Adenomas were found in 10% of the individuals and finding of adenomas was positively correlated to higher age. Men had adenomas in 15% and women in 6% of the cases. Women had a right-sided dominance of adenomas. Hyperplastic polyps were seen in 21% of the individuals. The presence of hyperplastic polyps was significantly positively correlated to the presence of adenomas. Advanced adenomas were seen in 2.8% of the study participants, but no cancers were detected. Conclusion. One in 10 healthy subjects had an adenoma but advanced adenomas were uncommon. Men and women have a different adenoma prevalence and localization. The results provide baseline European data for evaluating colonoscopy screening-protocols for colorectal cancer risk groups, and the findings may have implications for colon cancer screening in the normal, otherwise-healthy population.
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| 4. |
- Gaillard, Marie-José, 1953-, et al.
(författare)
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Holocene land-cover reconstructions for studies on land cover-climate feedbacks
- 2010
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Ingår i: Climate of the Past. - : Copernicus GmbH. - 1814-9324 .- 1814-9332. ; 6, s. 483-499
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Tidskriftsartikel (refereegranskat)abstract
- The major objectives of this paper are: (1) to review the pros and cons of the scenarios of past anthropogenic land cover change (ALCC) developed during the last ten years, (2) to discuss issues related to pollen-based reconstruction of the past land-cover and introduce a new method, REVEALS (Regional Estimates of VEgetation Abundance from Large Sites), to infer long-term records of past land-cover from pollen data, (3) to present a new project (LANDCLIM: LAND cover – CLIMate interactions in NW Europe during the Holocene) currently underway, and show preliminary results of REVEALS reconstructions of the regional land-cover in the Czech Republic for five selected time windows of the Holocene, and (4) to discuss the implications and future directions in climate and vegetation/land-cover modeling, and in the assessment of the effects of human-induced changes in land-cover on the regional climate through altered feedbacks. The existing ALCC scenarios show large discrepancies between them, and few cover time periods older than AD 800. When these scenarios are used to assess the impact of human land-use on climate, contrasting results are obtained. It emphasizes the need for methods such as the REVEALS model-based land-cover reconstructions. They might help to fine-tune descriptions of past land-cover and lead to a better understanding of how long-term changes in ALCC might have influenced climate. The REVEALS model is demonstrated to provide better estimates of the regional vegetation/landcover changes than the traditional use of pollen percentages. This will achieve a robust assessment of land cover at regional- to continental-spatial scale throughout the Holocene. We present maps of REVEALS estimates for the percentage cover of 10 plant functional types (PFTs) at 200 BP and 6000 BP, and of the two open-land PFTs “grassland” and “agricultural land” at five time-windows from 6000 BP to recent time. The LANDCLIM results are expected to provide crucial data to reassess ALCC estimates for a better understanding of the land suface-atmosphere interactions.
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| 5. |
- Grimby-Ekman, Anna, 1967, et al.
(författare)
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Prediction models for planning health care resources. During the first wave of the Covid-19 pandemic 2020
- 2022
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Due to the Covid-19 pandemic, has emphasized a need for planning health care resources based on only a few aggregated data points and little knowledge of the data-generating process. In the first part of the report, we present the process of our work in spring 2020 during the first wave and especially during the first part with the high demands on health care resources. In the second part of the report, we discuss the logistic growth model (LGM), one of our models used to predict the peak height and the peak timing. We present some different approaches to use the LGM, and compare these to a different data set, Belgium data. For the Swedish regional data, the LGM on raw observations gave a good estimate on the peak height. The adjusted LGM, using cumulative new inpatient beds, fitted the Swedish regional data to a satisfying degree. For the Belgium data, the LGM on raw observations gave a good estimate on peak height and timing. The adjusted LGM, using cumulative new inpatient beds, did not work for the Belgium data as it gave a too early peak time and a too low peak height. The experience from our work, in combination with now existing literature, the process in a similar future situation would include better knowledge on how to find and combine data to get as reliable forecasts as possible and to use creativity in combination with theoretical competence.
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| 6. |
- Hedenstierna-Jonson, Charlotte, 1971-, et al.
(författare)
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Viking Mobility in the Baltic Sea Region
- 2020
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Ingår i: Viking Encounters. - Aarhus : Aarhus University Press. - 978 87 7184 265 4 ; , s. 57-66
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Bokkapitel (refereegranskat)abstract
- Tough mobility and migration could be regarded as diagnostic features of the Viking Age, it is not possible to generalize and treat the Viking World as a homogenous society. Patterns of mobility and migration were linked to social structures and contexts. Studying the composition of the material culture within a site or individual context has been the prevailing method within archaeology to approach issues of mobility. Although this approach has acknowledged restrictions, it has been the method at hand. However, migration and mobility are not necessarily reflected in the material culture, meaning other approaches are called for. The first question to ask is: what variations in mobility patterns between urban and rural contexts are there, and are there indications of significant differences between various geographical regions? Even between sites characterized as trading posts (i.e. not rural), with similar material evidence of long-distance trade and advanced crafts, we might have significant differences, relating to the seasonal or permanent character of the site. In the following paper, we present the results from strontium isotope analyses on archaeological materials from a number of Viking-Age sites within present-day Sweden. The results of the analyses conducted within the ATLAS project will be compared to other isotope studies from Scandinavia, and discussed in relation to local, regional and supra-regional contexts. On a more local level, the possible cultural influence of migrants is investigated.
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| 7. |
- Hedenstierna-Jonson, Charlotte, et al.
(författare)
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Viking Mobility in the Baltic Sea Region
- 2020
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Ingår i: Viking encounters. - Aarhus : Aarhus Universitetsforlag. - 9788771842654 ; , s. 61-70
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Bokkapitel (refereegranskat)
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| 8. |
- Hugerth, Luisa W., et al.
(författare)
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No distinct microbiome signature of irritable bowel syndrome found in a Swedish random population
- 2020
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Ingår i: Gut. - : BMJ. - 0017-5749 .- 1468-3288. ; 69:6, s. 1076-1084
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Tidskriftsartikel (refereegranskat)abstract
- Objective The ethiopathogenesis of irritable bowel syndrome (IBS) is unknown. While a link to the gut microbiome is postulated, the heterogeneity of the healthy gut makes it difficult to draw definitive conclusions. We aimed to describe the faecal and mucosa-associated microbiome (MAM) and health correlates on a community cohort of healthy and IBS individuals with no colonoscopic findings.Design The PopCol study recruited a random sample of 3556 adults; 745 underwent colonoscopy. IBS was defined by Rome IV criteria and organic disease excluded. 16S rRNA gene sequencing was conducted on sigmoid biopsy samples from 376 representative individuals (63 IBS cases) and faecal samples from 185 individuals (32 IBS cases).Results While sigmoid MAM was dominated by Lachnospiraceae, faeces presented a higher relative abundance of Ruminococcaceae. Microbial richness in MAM was linearly correlated to that in faeces from the same individual (R-2=0.255, p<3E-11) as was diversity (R-2=0.06, p=0.0022). MAM diversity decreased with increasing body mass index (BMI; Pearson's r=-0.1, p=0.08) and poorer self-rated health (r=-0.15, p=0.007), but no other health correlates. Faecal microbiome diversity was correlated to stool consistency (r=-0.16, p=0.043). Several taxonomic groups were correlated to age, BMI, depression and self-reported health, including Coprococcus catus associated with lower levels of depression (r=-0.003, p=0.00017). The degree of heterogeneity observed between IBS patients is higher than that observed between healthy individuals.Conclusions No distinct microbial signature was observed in IBS. Individuals presenting with low self-rated health or high BMI have lower gut microbiome richness.
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| 9. |
- Ingvarsson, Anne, et al.
(författare)
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Bioarchaeological field analysis of human remains from the mass graves at Phaleron, Greece
- 2019
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Ingår i: Opuscula. - : Editorial Committee of the Swedish Institutes at Athens and Rome (ECSI). - 2000-0898. ; 12, s. 7-158
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Tidskriftsartikel (refereegranskat)abstract
- In 2016, archaeological excavations undertaken by the Ephorate of Antiquities of West Attica, Piraeus and Islands 3.8 km south-west of Athens, Greece, revealed mass burials of 79 skeletons in three rows. The burials are dated to the 7th century BC. The anthropological field documentation was undertaken by The Swedish Institute of Athens, and followed established bioarchaeological protocols regarding taphonomic processes, age, sex, injuries, and pathological changes. The descriptions and interpretations should be regarded as preliminary field observations. A majority of the individuals were young adult or juvenile males, most of them without signs of active disease and with a generally good oral health status, but with corroded iron shackles around their wrists. Cause of death could not be determined although extensive and likely perimortem fractures were observed. The only object related to injury and/or possible cause of death was an arrowhead found in the chest of one of the skeletons. Why and where the individuals were killed is a matter of conjecture; the observations from the field documentation neither validate, nor disprove the hypothesis that these individuals were captives and victims of the socalled "Cylonian conspiracy" in the 7th century BC.
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| 10. |
- Kjellström, Anna, et al.
(författare)
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Dietary patterns and social structures in medieval Sigtuna, Sweden, as reflected in stable isotope values in human skeletal remains
- 2009
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Ingår i: Journal of Archaeological Science. - : Elsevier BV. - 0305-4403 .- 1095-9238. ; 36:12, s. 2689-2699
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Tidskriftsartikel (refereegranskat)abstract
- Stable isotopes (delta C-13, delta N-15) have been studied in human burials from the medieval town Sigtuna in Sweden. Dietary patterns of 80 adult individuals were analyzed on three cemeteries representing the phases of establishment, prosperity and decline of the town. All analyzed individuals were radiocarbon dated. One of the cemeteries, Church 1, represents a population of higher social status than those at the other two cemeteries. The delta C-13 values are homogenous and showed that the protein intake was mainly of terrestrial origin in the whole population. delta N-15 values varies more and they may indicate a higher input of vegetables in the diet at one of the cemeteries, the Nunnan block. Already in the initial phases of Sigtuna a social hierarchy had been established which is reflected in dietary patterns. Apparently more animal protein was consumed among the high status population of the town. Furthermore, differences in dietary patterns between the sexes were noted. In all phases the females show more clustered values indicating a more homogeneous diet than that of the males.
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| 11. |
- Linderholm, Anna, et al.
(författare)
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Stable isotope analysis of a medieval skeletal sample indicative of systemic disease from Sigtuna Sweden
- 2011
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Ingår i: Journal of Archaeological Science. - : Elsevier BV. - 0305-4403 .- 1095-9238. ; 38:4, s. 925-933
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Tidskriftsartikel (refereegranskat)abstract
- In Sigtuna, Sweden, several medieval cemeteries have been excavated, from which approximately 800 skeletons have been excavated and analysed. Archaeological finds and anthropological analyses have exposed social differences between the cemeteries. Stable isotope analyses have shown that the inhabitants of the town consumed a mixed diet. Significant differences in dietary patterns between the cemeteries may be related to social stratification. In the outskirts of a churchyard excavated in 2006, bone changes showing systemic inflammatory disease indicative of leprosy were observed in six individuals. The burial location suggests that the affected belonged to a lower social stratum. Bone samples were taken from these six individuals, 19 other human skeletons and five animals from the same cemetery for analysis of the stable isotope composition of carbon (C), nitrogen (N) and sulphur (S). The results showed no significant differences in delta(13)C and delta(15)N values between the groups, i.e. the seemingly healthy humans and the humans affected by severe inflammatory disease appear to have had similar diets. Nor was a significant difference observed in delta(34)S data between the six affected individuals and the rest of the sample, implying that no difference in origins could be observed between the two groups studied. However, a comparison between the present study and the previous analysis resulted in significant differences in carbon values. Based on the results obtained in this investigation it is suggested that if a dietary difference existed between people in the outskirts of a cemetery (for example those suffering from leprosy) and people buried in higher ranked regions, it was not a difference in food source but rather in other parameters. Instead dietary differences and possibly social variations are demonstrated between cemeteries. The results from the present study highlight the hierarchical arrangements of social classes in the early medieval society.
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| 12. |
- Niskanen, Markku, et al.
(författare)
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Scandinavia and Finland
- 2018
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Ingår i: Skeletal Variation and Adaptation in Europeans. - Hoboken, NJ : Wiley-Blackwell. - 9781118627969 - 9781118628430 ; , s. 355-396
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Bokkapitel (refereegranskat)abstract
- This chapter focuses on Scandinavia, Finland, and adjacent regions of Northwest Russia (Karelia and the Kola Peninsula). Urbanization commenced relatively late in Scandinavia and Finland. The chapter examines temporal trends in body size and shape within Scandinavia and Finland across all time periods, followed by comparisons with other Europeans as well as other comparisons dealing with the Neolithic period Pitted Ware culture (PWC foragers), urban‐rural differences, and sexual dimorphism. The Neolithic PWC foragers are more similar to the Mesolithic foragers than to the Neolithic farmers in relative long bone bending strength. The PWC are a special case because, although foragers, they lived during the Scandinavian Middle Neolithic and were contemporary with Neolithic farmers. The chapter presents comparisons between Scandinavians and other Europeans in size‐standardized cross‐sectional properties for femoral A‐P and M‐L bending strengths, and torsional/average bending strengths of right and left humeri.
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| 13. |
- Rutgersson, Anna, 1971-, et al.
(författare)
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Natural hazards and extreme events in the Baltic Sea region
- 2022
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Ingår i: Earth System Dynamics. - : Copernicus Publications. - 2190-4979 .- 2190-4987. ; 13:1, s. 251-301
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Tidskriftsartikel (refereegranskat)abstract
- A natural hazard is a naturally occurring extreme event that has a negative effect on people and society or the environment. Natural hazards may have severe implications for human life and can potentially generate economic losses and damage ecosystems. A better understanding of their major causes, probability of occurrence, and consequences enables society to be better prepared to save human lives as well as to invest in adaptation options. Natural hazards related to climate change are identified as one of the Grand Challenges in the Baltic Sea region. Here, we summarize existing knowledge about extreme events in the Baltic Sea region with a focus on the past 200 years as well as on future climate scenarios. The events considered here are the major hydro-meteorological events in the region and include wind storms, extreme waves, high and low sea levels, ice ridging, heavy precipitation, sea-effect snowfall, river floods, heat waves, ice seasons, and drought. We also address some ecological extremes and the implications of extreme events for society (phytoplankton blooms, forest fires, coastal flooding, offshore infrastructure, and shipping). Significant knowledge gaps are identified, including the response of large-scale atmospheric circulation to climate change and also concerning specific events, for example, the occurrence of marine heat waves and small-scale variability in precipitation. Suggestions for future research include the further development of high-resolution Earth system models and the potential use of methodologies for data analysis (statistical methods and machine learning). With respect to the expected impacts of climate change, changes are expected for sea level, extreme precipitation, heat waves and phytoplankton blooms (increase), and cold spells and severe ice winters (decrease). For some extremes (drying, river flooding, and extreme waves), the change depends on the area and time period studied.
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| 14. |
- Talley, Nicholas J., et al.
(författare)
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Role of smoking in functional dyspepsia and irritable bowel syndrome : three random population-based studies
- 2021
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Ingår i: Alimentary Pharmacology and Therapeutics. - : John Wiley & Sons. - 0269-2813 .- 1365-2036. ; 54:1, s. 32-42
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Tidskriftsartikel (refereegranskat)abstract
- Background: It is uncertain if functional dyspepsia (FD) or irritable bowel syndrome (IBS) are linked to smoking, and smoking cessation is not part of the routine advice provided to these patients.Aim: To assess if smoking is an independent risk factor for FD and IBS.Methods: Three population-based endoscopy studies in Sweden with 2560 community individuals in total (mean age 51.5 years, 46% male). IBS (14.9%), FD (33.5%), and associated symptoms were assessed using the validated abdominal symptom questionnaire, and smoking (17.9%) was obtained from standardised questions during a clinic visit. The effect of smoking on symptom status was analysed in an individual person data meta-analysis using mixed effect logistic regression, adjusted for snuffing, age and sex.Results: Individuals smoking cigarettes reported significantly higher odds of postprandial distress syndrome (FD-PDS) (OR 10-19 cig/day = 1.42, 95% CI 1.04-1.98 P = 0.027, OR ≥20 cig/day = 2.16, 95% CI 1.38-3.38, P = 0.001) but not epigastric pain. Individuals smoking 20 or more cigarettes per day reported significantly higher odds of IBS-diarrhoea (OR = 2.40, 95% CI 1.12-5.16, P = 0.025), diarrhoea (OR = 2.01, 95%CI 1.28-3.16, P = 0.003), urgency (OR = 2.21, 95%CI 1.41-3.47, P = 0.001) and flatus (OR = 1.77, 95%CI 1.14-2.76, P = 0.012) than non-smokers. Smoking was not associated with IBS-constipation or IBS-mixed.Conclusion: Smoking is an important environmental risk factor for postprandial distress syndrome, the most common FD subgroup, with over a twofold increased odds of PDS in heavy smokers. The role of smoking in IBS-diarrhoea, but not constipation, is also likely important.
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| 15. |
- Östberg, Anna-Lena, et al.
(författare)
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The influence of social deprivation on dental caries in Swedish children and adolescents, as measured by an index for primary health care: The Care Need Index.
- 2017
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Ingår i: Community dentistry and oral epidemiology. - : Wiley. - 1600-0528 .- 0301-5661. ; 45:3, s. 233-241
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Tidskriftsartikel (refereegranskat)abstract
- The objective was to examine associations between a primary Care Need Index (CNI) and dental caries experience.Dental journal records for 300 988 individuals in western Sweden, aged 3-19 years in 2007-09, were completed with official socioeconomic information. The CNI (independent variable), originally developed for assessing primary care need, was calculated for residential areas (small areas, parishes, dental clinics) based on markers of material deprivation, sociodemographic characteristics, social instability and cultural needs. Dental caries (dependent variable) was registered using the decayed, missing, filled teeth (DMFT) system. Multilevel Poisson regression and logistic regression models were used. All analyses were adjusted for age and gender.In the most deprived areas, the incidence rate ratio (IRR) for dental caries was up to five times higher than in the most affluent areas (reference); in small areas, the IRR for decayed teeth (DT) was 3.74 (95% CI: 3.39-4.12) and 5.11 (CI: 4.45-5.87) for decayed surfaces approximally (DSa). Caries indices including fillings (decayed filled teeth [DFT], decayed filled surfaces approximally [DFSa]) produced lower IRRs, with similar pictures at the parish and dental clinic level. The intracluster correlation was low overall, but stronger at lower geographical levels. The odds ratios for ≥3 caries lesions in the two most deprived areas of the CNI deciles were high, with a DT OR of 3.55 in small areas (95% CI: 3.39-3.73), compared with the eight more affluent deciles.There were strong associations between an index for assessing need in primary care, the CNI and dental caries in Swedish children and adolescents.
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| 16. |
- Ahlin Sundman, Elin, et al.
(författare)
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Medieval Masculinities and Violence : Weapon-Related Trauma in Skeletal Assemblages from Two Religious Houses in Iceland and Sweden
- 2020
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Ingår i: European Journal of Archaeology. - : Cambridge University Press (CUP). - 1461-9571 .- 1741-2722. ; 23:4, s. 567-584
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Tidskriftsartikel (refereegranskat)abstract
- Previous research has shown that physical violence had a normative presence in medieval Nordic societies. In this study, weapon-related trauma (WRT) was examined in human skeletal assemblages from two religious houses, Skriouklaustur in Iceland, and Vasteras in Sweden. The aims were to identify patterns of WRT and to relate these to the masculinities of different groups of men. Violence was a prominent component of identity among lay men, especially for men with warrior experience. The use of violence was more problematic among clerics. The hypothesis that these notions of ideal masculine behaviour would affect the ways in which masculinities were enacted and would be reflected in the patterns of WRT was borne out by the results of this study. No WRT was identified among the canons and lay brothers in Skriouklaustur, but it was present in about thirty per cent of the males interpreted as belonging to the lay elite buried in the northern part of the church at Vasteras.
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| 17. |
- Ahlin Sundman, Elin, et al.
(författare)
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Signs of sinusitis in times of urbanization in Viking Age-early Medieval Sweden
- 2013
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Ingår i: Journal of Archaeological Science. - : Elsevier BV. - 0305-4403 .- 1095-9238. ; 40:12, s. 4457-4465
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Tidskriftsartikel (refereegranskat)abstract
- The influence and possible negative impact on sinus health of living conditions in rural and urban environments in Viking Age (AD 800–1050) and Early Medieval Sweden (AD 1050–1200) is investigated. Skeletal samples from 32 rural settlements in the Mälaren Valley (AD 750–1200) and burials in the nearby proto-urban port of trade Birka (AD 750–960) are examined. Based on the diagnostic criteria for maxillary sinusitis used in earlier studies, the results show that there is no significant difference in the prevalence of signs of sinusitis between the two materials (i.e. the Mälaren Valley versus Birka). Consequently, this provides no evidence that living in a proto-urban environment had a negative impact on sinus health. However, when compared with previously studied samples from the early medieval town Sigtuna, dated to AD 970–1100, the populations of the Mälaren Valley and Birka show significantly lower frequencies of bone changes interpreted as chronic maxillary sinusitis (95%, 70% and 82% respectively). This implies that the urban environment of Sigtuna could have led to impaired sinus health. There is also a significant difference between males and females in the Birka material, in which more females (100%) than males (68%) were affected. A gender based differentiation in work tasks is suggested by this, or exposure to environmental risk factors that affect sinus health. No difference between males and females could be detected in the samples from the Mälaren Valley and Sigtuna.
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| 18. |
- Alfsdotter, Clara, 1988-, et al.
(författare)
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A Taphonomic Interpretation of the Postmortem Fate of the Victims Following the Massacre at Sandby Borg, Sweden
- 2020
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Ingår i: Bioarchaeology International. - Gainesville, FL : University of Florida Press. - 2472-8357 .- 2472-8349. ; 3:4, s. 262-282
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Tidskriftsartikel (refereegranskat)abstract
- In the ringfort Sandby borg (A.D. 400–550) on Öland, Sweden, remains of 26 unburied humans were excavated between 2010 and 2016. Several of the skeletons display traces of lethal interpersonal violence. This study presents taphonomic analyses of unburied bodies, a situation seldom encountered archaeologically. The depositional context allows us to investigate human taphonomy in interaction with natural agents both “indoors” and “outdoors.” A set of various techniques, including documentation of preservation via zoning, weathering stages, fracture analysis, and archaeothanatology, were applied to understand the perimortem and postmortem fate of the human remains. The results of the taphonomic analysis showed no indications of manipulation postmortem. Expected differences in preservation between in-and outdoor skeletons were not observed. Perimortem fire alterations were interpreted as the result of burning hearths and smoldering roofs. The analysis indicates that the bodies have decomposed in voids. New observations for “unconfined void” taphonomy are presented. The abduction of limbs could be the result of bloating and, hence, indicate a primary deposit of bodies. Atypical lack of splaying of bones might be caused by decomposition in unconfined voids, possibly allowing quicker drainage of putrefaction liquids than in confined voids such as coffins. These observations suggest that processes behind decomposition in voids are not completely understood archaeologically, and might challenge interpretations of mortuary treatment from human remains.
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| 19. |
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| 20. |
- Alfsdotter, Clara, 1988-, et al.
(författare)
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The Sandby Borg Massacre : Interpersonal Violence and the Demography of the Dead
- 2019
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Ingår i: European Journal of Archaeology. - : Cambridge University Press. - 1461-9571 .- 1741-2722. ; 22:2, s. 210-231
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Tidskriftsartikel (refereegranskat)abstract
- During excavations of the Iron Age ringfort of Sandby borg (ad 400-550), the remains of twenty-six unburied bodies were encountered inside and outside the buildings. The skeletons and the archaeological record indicate that after the individuals had died the ringfort was deserted. An osteological investigation and trauma analysis were conducted according to standard anthropological protocols. The osteological analysis identified only men, but individuals of all ages were represented. Eight individuals (31 per cent) showed evidence of perimortem trauma that was sharp, blunt, and penetrating, consistent with interpersonal violence. The location of the bodies and the trauma pattern appear to indicate a massacre rather than a battle. The 'efficient trauma' distribution (i.e. minimal but effective violence), the fact that the bodies were not manipulated, combined with the archaeological context, suggest that the perpetrators were numerous and that the assault was carried out effectively. The contemporary sociopolitical situation was seemingly turbulent and the suggested motive behind the massacre was to gain power and control.
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| 21. |
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| 22. |
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| 23. |
- Arcini, Caroline, et al.
(författare)
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Living conditions in times of plague
- 2015
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Ingår i: Environment, Society and the Black Death. - : Oxbow Books. - 9781785700545
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 24. |
- Avby, Gunilla, 1965-, et al.
(författare)
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Shaping leadership development systems to the work context
- 2022
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Konferensbidrag (refereegranskat)abstract
- The paper seeks to identify patterns of leadership development in different organization contexts with the aim of contributing to improved understanding of how the context shapes the leadership development system (LDS).Design/methodology/approach: This study is based on the initial phase of a 4-year collaborative research project on LDSs. Data was collected in the five collaborative partner organizations and based on four data sources: 1) company visits; 2) internal documentation; 3) external information (websites); and 4) company presentations at an on-line workshop.Findings: The results show a strong focus on individual leader development, and at least partly, confirms the under-use of developmental assignments and relationships as shown in previous studies. All organizations outsource leadership development to different degrees. However, leadership development is not only structured through different methods, it is also dependent on the organization context in the form of leader forums and meetings. An identified pattern is that the smaller organizations are more dependent on external resources, and the larger organizations tailor company-wide programs for their unique needs together with external consultants. Furthermore, the LDS is believed to be an effective change agent in the adaptive process of transforming.Originality: This study contributes to the research on leadership development by advancing the current understanding of how leadership development interacts with the context of the organization.Practical implications: This study highlights the need for leaders and HR professionals to acknowledge contextual issues when choosing practices used for developing the leadership in the organization.
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| 25. |
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| 26. |
- Bergmo-Prvulovic, Ingela, 1970-, et al.
(författare)
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Exploring Social Representations of Leadership Development : Designing for Work-Integrated Learning
- 2022
-
Ingår i: International Conference on Work Integrated Learning. - Trollhättan : University West. - 9789189325302 ; , s. 83-86
-
Konferensbidrag (refereegranskat)abstract
- This paper explored social representations of leadership and leadership development shaping an organizations leadership development system (LDS). This study is based on the initial phase of a 4-year collaborative research project on LDSs, adopting an interactive research approach to co-produce knowledge through joint meetings and learning workshops (Ellström et al., 2020). The research project involves researchers from different disciplines, and five organizations operating in different business domains. The participating organizations vary in terms of size, strategies, markets, processes, products, and ways of organizing, but they all share a common interest in how to develop sustainable approaches to leadership development. An LDS encompasses all the metho ds and practices in an organization that contribute to developing and producing effective leaders (McCauley et al 2010). The importance of understanding the characteristics of the context the LDS is embedded in has been highlighted in a previous study (Avby et al., 2022), and serve as a point-of-reference in this study. However, less is known of what underlying assumptions an LDS is based upon. This study paid attention to the underlying values, ideas, and perspectives on leadership and leadership development that shape an organizations’ ways of thinking, communicating, and acting in the LDS. We suggest that the potential to develop a more deliberate practice of leadership development was enhanced by exploring and articulating the tacit knowledge and assumpt ions that an LDS rests upon.Aim The aim of this study was to explore how socially and contextually shaped assumptions on leadership and leadership development can be visualized and practically applied to develop the leadership in the organization. The question addressed was how the awareness of underlying assumptions can support the methods and practices applied, and in what way the disclosing of underlying ideas, values and practices may foster work -integrated learning?Design and methods From a social representation theory approach (Moscovici, 2001, Jovchelovitch, 2007, Markova, 2003, BergmoPrvulovic, 2015), underlying assumptions of leadership and leadership development were explored. In the collaborative project an initial mapping of the participating organizations’ LDSs has been co nducted, based on different sources of data. The results of this mapping have been presented through a metaphorical analysis (Avby et al., 2022), in which the participating organizations are described with certain metaphors of their LDS. This study paid specific attention to the organization entitled The Self-Managing Team, and added to the initial stage of mapping LDSs by exploring the underlying assumptions that underpins the expressions and formulations on leadership and leadership development found in the organization’s documents, websites, formulations in meetings and strategies. The exploration of social representations of LDSs was based upon the free association method (Abric, 1995), further developed, and used in studies exploring social representations of similar abstract and complex phenomena, such as career (Bergmo-Prvulovic, 2013: 2015). The method consists of questions, words and series of words given to the respondents who spontaneously write down their immediate associations towards a specific concept and complex phenomenon with a gradual deepening of questions related to specific words, series of words. In this study, a digital enquiry was created in Esmaker. The enquiry was designed to ask for respondents spontaneous, immediate thoughts on words, and series of words related to leadership and leadership development. The gradually deepening of questions, were designed by paying attention to the five dimensions of representations suggested by Jovchelovitch (2007), by exploring who are concerned, why and for what leadership is needed, what is the content 84 of leadership, when it works and doesn’t work, when and how it occurs as well who is responsible, whose engagement and what conditions are needed. This study was based on 19 respondents’ answers a ll member in the Self-Managing Team. They were selected by the organization, as identified having important roles and functions in the company’s LDS. A facilitator in the organization introduced an online enquiry with 12 questions, given one by one to the respondents, providing 1-2 minutes for each. The respondents wrote down their associations to each question, some background data, and questions about leadership identity. The analytical procedure was made according to qualitative content analysis method as the basic procedure of qualitatively exploring social representations (Bergmo-Prvulovic, 2013; 2015). Expressions were numbered with a certain code for each respondent related to each answered question, thereafter each textual units were condensed, meaning units were coded and grouped into constitutive elements that builds up preliminary and primary themes generating a web of social representations of LDS for the group of respondents.Preliminary results The results disclosed a web of underlying social representations shaping the LDS in The Self-Managing Team. The social representations shape a basic, contextually characterized system of values, ideas, and practices, on which the company at present form their LDS. Given the collaborative design of the project, the results were fed back to the organization to validate the analytical procedure, as well as to support the designing for work -integrated learning and further knowledge use in the organization. The results revealed the respondents’ assumptions on leadership, leadership development, and self-leadership. These assumptions are clearly anchored in the organization’s aim to build in self-management, as a collective way of working with leadership. However, the existing knowledge base encloses both commonalities and contradictions that needs to be further highlighted to create a sustainable LDS. Results showed both stable representations, that occur repeatedly throughout the material, and dynamic social rep resentations, that express a negotiating character between different views, or as being antinomies of thoughts. By identifying and raising awareness of ambiguities deriving from the results, a base of designing for reflective work-integrated learning was provided. A joint learning process to discuss how the results could be utilized as a tool for work-integrated learning was initiated. Some challenges were recognized, and the organization especially addressed the need to work with a second step of workplace reflection. A first learning cycle was initiated to be continuously developed by involving the employees in the process. In all, the contribution of the study explains the basis of leadership development practice, which unnoticed might create ambiguity in service delivery. The mapping of social representations of an LDS can be utilized as a tool for a more deliberate leadership development practice and highlight possibilities and challenges that need to be addressed for integrating methods and practices in everyday work.
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| 27. |
- Björk Brämberg, Elisabeth, et al.
(författare)
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Access to primary and specialized somatic health care for persons with severe mental illness: a qualitative study of perceived barriers and facilitators in Swedish health care
- 2018
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Ingår i: BMC Family Practice. - : Springer Science and Business Media LLC. - 1471-2296. ; 19
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Tidskriftsartikel (refereegranskat)abstract
- Background: Persons with severe mental illness (e.g. schizophrenia, bipolar disorder) have a high prevalence of somatic conditions compared to the general population. Mortality data in the Nordic countries reveal that these persons die 15-20 years earlier than the general population. Some factors explaining this high prevalence may be related to the individuals in question; others arise from the health care system's difficulty in offering somatic health care to these patient groups. The aim of the present study was therefore to explore the experiences and views of patients, relatives and clinicians regarding individual and organizational factors which facilitate or hinder access to somatic health care for persons with severe mental illness. Methods: Flexible qualitative design. Data was collected by means of semi-structured individual interviews with patients with severe mental illness, relatives and clinicians representing primary and specialized health care. In all, 50 participants participated. Results: The main barrier to accessing somatic care is the gap between the organization of the health care system and the patients' individual health care needs. This is observed at both individual and organizational level. The health care system seems unable to support patients with severe mental illness and their psychiatric-somatic comorbidity. The main facilitators are the links between severe mental illness patients and medical departments. These links take the form of functions (i.e. systems which ensure that patients receive regular reminders), or persons (i.e. professional contacts who facilitate patients' access the health care). Conclusions: Health care services for patients with severe mental illness need reorganization. Organizational structures and systems that facilitate cooperation between different departments must be put in place, along with training for health care professionals about somatic disease among psychiatric patients. The links between individual and organizational levels could be strengthened by introducing professional contacts, such as liaison physicians and case managers. This is also important to reduce stress and responsibility among relatives.
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| 28. |
- Bus, Magdalena M., et al.
(författare)
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Mitochondrial DNA analysis of a Viking age mass grave in Sweden
- 2019
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Ingår i: Forensic Science International. - : Elsevier BV. - 1872-4973 .- 1878-0326. ; 42, s. 268-274
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Tidskriftsartikel (refereegranskat)abstract
- In 1998, a Viking Age mass grave was discovered and excavated at St. Laurence's churchyard in Sigtuna, Sweden. The excavated bones underwent osteoarchaeological analysis and were assigned to at least 19 individuals. Eleven skeletons showed sharp force trauma from bladed weapons. Mass graves are an unusual finding from this time period, making the burial context extraordinary. To investigate a possible maternal kinship among the individuals, bones and teeth from the skeletal remains were selected for mitochondrial DNA (mtDNA) analysis. Sanger sequencing of short stretches of the hypervariable segments I and II (HVS-I and HVS-II) was performed. A subset of the samples was also analysed by massively parallel sequencing analysis (MPS) of the entire mtDNA genome using the Precision ID mtDNA Whole Genome Panel. A total of 15 unique and three shared mtDNA profiles were obtained. Based on a combination of genetic and archaeological data, we conclude that a minimum of 20 individuals was buried in the mass grave. The majority of the individuals were not maternally related. However, two possible pairs of siblings or mother-child relationships were identified. All individuals were assigned to West Eurasian haplogroups, with a predominance of haplogroup H. Although the remains showed an advanced level of DNA degradation, the combined use of Sanger sequencing and MPS with the Precision ID mtDNA Whole Genome Panel revealed at least partial mtDNA data for all samples.
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| 29. |
- Canaviri Paz, Pamela Rosario, et al.
(författare)
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Effects on Microbiota Composition after Consumption of Quinoa Beverage Fermented by a Novel Xylose-Metabolizing L. plantarum strain
- 2021
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Ingår i: Nutrients. - : MDPI AG. - 2072-6643. ; 13:10
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Tidskriftsartikel (refereegranskat)abstract
- Demands for novel lactic acid bacteria with potential to be used as probiotics along with healthy fermented plant-based products increase worldwide. In this study, a novel Lactiplantibacillus plantarum P31891 strain with enzymatic capacity to degrade tannins and ferment xylose was used as starter culture for fermentation of a quinoa-based beverage. The probiotic potential of the selected strain was evaluated in healthy volunteers. Twenty participants consumed the beverage for 14 days; microbiota changes in saliva and faecal samples were analyzed by Terminal Restriction Fragment Length Polymorphism (T-RFLP), Next Generation Sequencing (NGS) and qPCR; and gastrointestinal well-being and digestive symptoms were recorded. The results indicated that the consumption of the beverage with Lactiplantibacillus plantarum P31891 in a probiotic dose (1012 CFU/mL) increased the number of Lactobacillus in the feces but not in saliva. Overall, the bacterial community did not seem to be influenced by the bacterium or by the beverage, as expressed by the diversity indexes, butspecific genera were affected, as reflected in changes in amplicon sequence variants. Consequently, Lactiplantibacillus plantarum P31891 showed potential to be categorized as a probiotic strain in the fermented quinoa-based beverage.
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| 30. |
- Cardiakidis Myers, Anna, et al.
(författare)
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Rifabutin accumulates in the lens and reduces retinal function in the rabbit eye
- 2009
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Ingår i: Retina. - 0275-004X. ; 29:1, s. 106-111
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Tidskriftsartikel (refereegranskat)abstract
- PURPOSE: To study the toxicology of rifabutin in the rabbit eye with emphasis on retinal function and histopathology.METHODS: Seven rabbits received a daily dose of rifabutin during 15 months. Six rabbits receiving only the vehicle were used as controls. Repeated standardized full-field electroretinograms (ERG) were assessed. After discontinuing treatment, the rabbits were killed and the cornea, the lens, and the sectioned retina was studied. Immunhistochemistry directed against vimentin, glial fibrillaryacidic protein (GFAP), protein kinase C (PKC), and peanut agglutinin (PNA) was performed.RESULTS: Rifabutin was detected in serum of the treated rabbits. During treatment, the full-field ERG demonstrated significantly reduced b-wave amplitudes in the total rod-cone response as well as in the isolated rod and cone response compared with the recordings before treatment. The control rabbits did not demonstrate a reduction of the ERG amplitudes. The treated rabbits developed a discoloration of the lens, not seen in the control group. No retinal pathology was demonstrated using immunohistochemical methods.CONCLUSION: Rifabutin causes a discoloration of the lens and reduces both rod and cone function in rabbits, but does not alter retinal morphology. Previous reports on ocular side effects caused by rifabutin are supported by the results of this study.
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| 31. |
- Chen, Deliang, 1961, et al.
(författare)
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Summary of a workshop on extreme weather events in a warming world organized by the Royal Swedish Academy of Sciences
- 2020
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Ingår i: Tellus Series B-Chemical and Physical Meteorology. - : Stockholm University Press. - 1600-0889 .- 0280-6509. ; 72:1
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Tidskriftsartikel (refereegranskat)abstract
- Climate change is not only about changes in means of climatic variables such as temperature, precipitation and wind, but also their extreme values which are of critical importance to human society and ecosystems. To inspire the Swedish climate research community and to promote assessments of international research on past and future changes in extreme weather events against the global climate change background, the Earth Science Class of the Royal Swedish Academy of Sciences organized a workshop entitled 'Extreme weather events in a warming world' in 2019. This article summarizes and synthesizes the key points from the presentations and discussions of the workshop on changes in floods, droughts, heat waves, as well as on tropical cyclones and extratropical storms. In addition to reviewing past achievements in these research fields and identifying research gaps with a focus on Sweden, future challenges and opportunities for the Swedish climate research community are highlighted.
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| 32. |
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| 33. |
- Drew, Rose, et al.
(författare)
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Sacralization in the Mary Rose and Kronan assemblages : An inconsistently recorded anomaly
- 2021
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Ingår i: International journal of osteoarchaeology. - : Wiley. - 1047-482X .- 1099-1212. ; 31:5, s. 683-700
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Tidskriftsartikel (refereegranskat)abstract
- This study aims to promote consistent observations of sacralization, a relatively common form of lumbosacral transitional vertebrae (LSTV). Sacralization can inform on genetic affiliation. There are four types, ranging from enlarged transverse processes to bony ankylosis. Complete sacralization reportedly occurs in 1.5%-14% of archeological and modern populations, yet clinical studies can conflate types, resulting in rates as high as 46%. Archeologically obtained sacra and lower lumbar vertebrae from two historical shipwrecks (16th century English warship Mary Rose and 17th century Swedish warship Kronan) are compared via gross observation. These semi-documented individuals, fit enough to be on a warship during battle, have a documented cause, manner, and date of death. The assemblages yield 120 sacra; complete sacralization is compared between the crews. Both crude and true prevalence of bony ankyloses are recorded with chi(2) analyses testing significance. Both samples have 16.7% true prevalence of complete sacralization, with 38.3% of Mary Rose sacra and 26.7% of Kronan sacra showing some variant of LSTV. It is possible the high rates of sacralization shown in both crews are related to the samples being drawn from similar populations: a Swedish clinical study finds a similar rate of 13.9% for complete sacralization. However, reported rates of less than 1.0% in other archeological samples suggest that true sacralization is inconsistently recognized. Finally, clinical and archeological studies either conflate all types or fail to state their diagnostic criteria, reducing the ability to accurately compare findings.
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| 34. |
- Economou, Christos, et al.
(författare)
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Ancient-DNA reveals an Asian type of Mycobacterium leprae in medieval Scandinavia
- 2013
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Ingår i: Journal of Archaeological Science. - : Elsevier BV. - 0305-4403 .- 1095-9238. ; 40:1, s. 465-470
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Tidskriftsartikel (refereegranskat)abstract
- Leprosy is a chronic infection of the skin and peripheral nerves caused by the pathogen Mycobacterium leprae. Its impact on human populations and societies of the past as well as its phylogeographic patterns around the world – at least in modern times – has been well documented. This slow growing bacterium has been shown to exist in distinct ‘SNP types’ that occur in relatively defined parts of the globe. The routes that the disease followed in the past are, however, still uncertain. This study of ancient-DNA typing of archaeological human remains from Sweden dated to early Medieval times provides genetic evidence that a transmission of M. leprae ‘SNP subtype’ 2G – found mainly in Asia – took or had already taken place at that time from the Middle East to Scandinavia. This finding is unique in the history of leprosy in Europe. All human specimens from this continent – both modern and ancient – that have been tested to date showed that the one responsible for the infection strains of M. leprae belong to ‘SNP type’ 3, whereas our results show that there were some European populations that were hosts to bacteria representing ‘SNP type’ 2 of the species as well.
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| 35. |
- Ericsson, Iréne
(författare)
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Välbefinnande och demens : Aspekter på välbefinnande hos äldre personer med måttlig till svår demens
- 2011
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Personer som lever med demenssjukdom såväl som mentalt friska människor behöver uppleva välbefinnande. Ett viktigt mål i vården och omsorgen av personer med demens är därför att hitta vägar för att försöka främja välbefinnande hos personen. Avhandlingens övergripande syfte varatt utveckla kunskap om aspekter av betydelse för att äldre personer med måttlig till svår demens ska uppleva välbefinnande. Avhandlingen baseras på empiriskt material från fyra delstudier. Den första delstudien, I(etnografi) genererade fältanteckningar från 31 observationstillfällen samt nio kvalitativa intervjuer med vårdgivare, så kallade kontaktmän till personen med demens. Delstudie II(testutveckling/tvärsnittsstudie) utgjordes av 336 testprotokoll som bearbetades statistiskt. Materialet i delstudie III (reformulerad grundad teori) innefattade 18 kvalitativa intervjuer med personer med demens samt 18 observationsprotokoll från observation av icke-verbalt språk. Den sista delstudien (IV) (konstruktivistisk grundad teori) bestod av fältanteckningar från 24 videoinspelningar av Egentids-situationer och 24 kvalitativa intervjuer med personer med demens samt åtta kvalitativa intervjuer med vårdgivare. Resultatet från avhandlingens studier visar att de kognitivt friska personerna som finns i personens närhet har en avgörande betydelse för upplevelsen av välbefinnande hos personer med måttlig till svår demens. För att interaktion ska vara önskvärd och ge välbefinnande måste den mentalt friska parten ha kunskap och insikt om att det finns en större medvetenhet hos personen med måttlig till svår demens än vad det omedelbara intrycket av förmågor ger. Om denna insikt saknas finns risk att interaktionen kan leda till kränkning i stället för välbefinnande. Det är förmodligen av betydelse att ha kunskap om och försöka fånga personens kvarvarande förmågor istället för att fokusera på brister. Kunskap om kvarvarande förmågor och till exempel överinlärda förmågor som fångas i anpassade test kan bidra till en mer positiv syn på personen och innebära att kvarvarande förmågor bättre tas tillvara, vilket kan bidra till välbefinnande. Personen med måttlig till svår demens kan kommunicera ett välbefinnande men det kräver lyssnarens förmåga och förmåga att tolka. Det kan också kräva en del praktiska ansträngningar med hänsyn till personens kognitiva nedsättningar som till exempel hjälpmedel i form av bilder och ting. Förmodligen ger interaktion som leder till en relation alltid en upplevelse av välbefinnande. Tid är en avgörande faktor för att upprätta relationer som ger välbefinnande hos personer med måttlig till svår demens. Det är därför viktigt att i vården avsätta tillräcklig tid, som vid till exempel Egentid, för att upprätta relationer och därigenom främja välbefinnande.
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| 36. |
- Fabisch, Anna, et al.
(författare)
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Transformations towards an integrated leadership development system : A longitudinal study in a high-performing public organization
- 2024
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Ingår i: Leadership. - : Sage Publications. - 1742-7150 .- 1742-7169.
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Tidskriftsartikel (refereegranskat)abstract
- Leadership development (LD) plays a significant role in achieving high-quality performance and business results, but there is little research on how leadership development itself evolves as the organization develops. This study explores how a leadership development system evolved over 30 years, during a time when the organization became increasingly high performing. Through reflexive thematic analysis of organizational documents and interviews with top managers and practitioners, the study provides a rich longitudinal description of the evolvement. The results revealed three pervasive changes of the leadership development system: 1) from a system for business-specific learning to one for system-wide learning; 2) from a system for personal development to one for customer-oriented quality development; and 3) from a leadership development system consisting of leadership development programs to one that is integrated into regular meetings and uses simple rules. These changes supported the gradual transformation of the leadership development from being independent to becoming integrated in the wider system, supporting the business system. The findings offer a unique insight into how an organization transitioned from individual leader development towards promoting collective aspects of leadership development. The study provides two main theoretical contributions that support the perspective of viewing leadership development as integrated within organizational development. Firstly, we present a more multifaceted way of understanding leadership development, wherein managers and employees, customer outcomes, and business advancement are seen as mutually developing. Secondly, we introduce two new critical points that complement previous descriptions of an advanced leadership development system: It is system wide (not only business specific) and customer oriented (not only leader/participant oriented).
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| 37. |
- Fahlander, Fredrik, 1965-, et al.
(författare)
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Beyond Sight: Archaeologies of Sensory Perception
- 2010. - 200
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Ingår i: Making Sense of Things: Archaeologies of Sensory Perception. - Stockholm : Univ.. ; , s. 1-13
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 38. |
- Ferrannini, Giulia, et al.
(författare)
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Long-term prognosis after a first myocardial infarction : eight years follow up of the case-control study PAROKRANK
- 2022
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Ingår i: Scandinavian Cardiovascular Journal. - : Informa UK Limited. - 1401-7431 .- 1651-2006. ; 56:1, s. 337-342
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Tidskriftsartikel (refereegranskat)abstract
- Objective. To explore long-term cardiovascular outcomes and mortality in patients after a first myocardial infarction (MI) compared with matched controls in a contemporary setting. Methods. During 2010-2014 the Swedish study PAROKRANK recruited 805 patients <75 years with a first MI and 805 age-, gender-, and area-matched controls. All study participants were followed until 31 December 2018, through linkage with the National Patient Registry and the Cause of Death Registry. The primary endpoint was the first of a composite of all-cause death, non-fatal MI, non-fatal stroke, and heart failure hospitalization. Event rates in cases and controls were calculated using a Cox regression model, subsequently adjusted for baseline smoking, education level, and marital status. Kaplan-Meier curves were computed and compared by log-rank test. Results. A total of 804 patients and 800 controls (mean age 62 years; women 19%) were followed for a mean of 6.2 (0.2-8.5) years. The total number of primary events was 211. Patients had a higher event rate than controls (log-rank test p < .0001). Adjusted hazard ratio (HR) for the primary outcome was 2.04 (95% CI 1.52-2.73). Mortality did not differ between patients (n = 38; 4.7%) and controls (n = 35; 4.4%). A total of 82.5% patients and 91.3% controls were event-free during the follow up. Conclusions. In this long-term follow up of a contemporary, case-control study, the risk for cardiovascular events was higher in patients with a previous first MI compared with their matched controls, while mortality did not differ. The access to high quality of care and cardiac rehabilitation might partly explain the low rates of adverse outcomes.
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| 39. |
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| 40. |
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| 41. |
- Gummesson, Sara, et al.
(författare)
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Keep your head high : skulls on stakes and cranial trauma in Mesolithic Sweden
- 2018
-
Ingår i: Antiquity. - : Antiquity Publications. - 0003-598X .- 1745-1744. ; 92:361, s. 74-90
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Tidskriftsartikel (refereegranskat)abstract
- The socio-cultural behaviour of Scandina-vian Mesolithic hunter-gatherers has been difficult to understand due to the dearth of sites thus far investigated. Recent excavations at Kanaljorden in Sweden, however, have revealed disarticulated human crania intentionally placed at the bottom of a former lake. The adult crania exhibited antemortem blunt force trauma patterns differentiated by sex that were probably the result of interpersonal violence; the remains of wooden stakes were recovered inside two crania, indicating that they had been mounted. Taphonomic factors suggest that the human bodies were manipulated prior to deposition. This unique site challenges our understanding of the handling of the dead during the European Mesolithic.
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| 42. |
- Hedenstierna-Jonson, Charlotte, 1971-, et al.
(författare)
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A female Viking warrior confirmed by genomics
- 2017
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Ingår i: American Journal of Physical Anthropology. - : Wiley. - 0002-9483 .- 1096-8644. ; 164:4, s. 853-860
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Tidskriftsartikel (refereegranskat)abstract
- ObjectivesThe objective of this study has been to confirm the sex and the affinity of an individual buried in a well-furnished warrior grave (Bj 581) in the Viking Age town of Birka, Sweden. Previously, based on the material and historical records, the male sex has been associated with the gender of the warrior and such was the case with Bj 581. An earlier osteological classification of the individual as female was considered controversial in a historical and archaeological context. A genomic confirmation of the biological sex of the individual was considered necessary to solve the issue.Materials and methodsGenome-wide sequence data was generated in order to confirm the biological sex, to support skeletal integrity, and to investigate the genetic relationship of the individual to ancient individuals as well as modern-day groups. Additionally, a strontium isotope analysis was conducted to highlight the mobility of the individual.ResultsThe genomic results revealed the lack of a Y-chromosome and thus a female biological sex, and the mtDNA analyses support a single-individual origin of sampled elements. The genetic affinity is close to present-day North Europeans, and within Sweden to the southern and south-central region. Nevertheless, the Sr values are not conclusive as to whether she was of local or nonlocal origin.DiscussionThe identification of a female Viking warrior provides a unique insight into the Viking society, social constructions, and exceptions to the norm in the Viking time-period. The results call for caution against generalizations regarding social orders in past societies.
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| 43. |
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| 44. |
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| 45. |
- Jaarsma, Tiny, et al.
(författare)
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Research in cardiovascular care: A position statement of the Council on Cardiovascular Nursing and Allied Professionals of the European Society of Cardiology
- 2014
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Ingår i: European Journal of Cardiovascular Nursing. - : Oxford University Press (OUP). - 1474-5151 .- 1873-1953. ; 13:1, s. 9-21
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Tidskriftsartikel (refereegranskat)abstract
- To deliver optimal patient care, evidence-based care is advocated and research is needed to support health care staff of all disciplines in deciding which options to use in their daily practice. Due to the increasing complexity of cardiac care across the life span of patients combined with the increasing opportunities and challenges in multidisciplinary research, the Science Committee of the Council on Cardiovascular Nursing and Allied Professionals (CCNAP) recognised the need for a position statement to guide researchers, policymakers and funding bodies to contribute to the advancement of the body of knowledge that is needed to further improve cardiovascular care. In this paper, knowledge gaps in current research related to cardiovascular patient care are identified, upcoming challenges are explored and recommendations for future research are given.
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| 46. |
- Khatib, Rani, et al.
(författare)
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Evaluating the Extent of Patient-Centred Care in a Selection of ESC Guidelines
- 2020
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Ingår i: European Heart Journal - Quality of Care and Clinical Outcomes. - : Oxford University Press. - 2058-5225 .- 2058-1742. ; 6:1, s. 55-61
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: Patient-centred care (PCC) is the cornerstone for healthcare professionals (HCP) to promote high quality care for patients with cardiovascular conditions. It is defined as 'Providing care that is respectful of, and responsive to, individual patient preferences, needs and values, and ensuring that patient values guide all clinical decisions'. PCC can improve patient outcomes and allow patients and HCP to manage care collaboratively using best available evidence. However, there is no clear understanding how extensively these guidelines incorporate PCC recommendations. The aim of the study was to evaluate the incorporation of PCC into a selection of guidelines published by the European Society of Cardiology (ESC).METHODS: Using a narrative literature review and expert consensus, the Science Committee within the Cardiovascular Nursing and Allied Professions (ACNAP) developed a checklist to determine PCC incorporation in clinical guidelines. Nine ESC guidelines were reviewed evaluated with committee members independently evaluating five PCC aspects: patient voice & involvement, multidisciplinary involvement, holistic care recommendations, flexibility to meet patients' needs, and provision of patient tools. The level of congruence in item ratings by experts was then compared.RESULTS: The incorporation of PCC using these respective five categories, ranged from 4% (patient tools) to 53% in the 'multidisciplinary involvement' category.CONCLUSIONS: Overall, the inclusion of PCC was low, indicating that patient perspectives and needs were less likely to be taken into account when developing, endorsing or formulating recommendations. Future development of guidelines should ensure better incorporation of patients' perspective, in particular, and other PCC aspects highlighted in this study.
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| 47. |
- Kirdok, Emrah, et al.
(författare)
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Metagenomic analysis of Mesolithic chewed pitch reveals poor oral health among stone age individuals
- 2024
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Ingår i: Scientific Reports. - : Springer Nature. - 2045-2322. ; 13:1
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Tidskriftsartikel (refereegranskat)abstract
- Prehistoric chewed pitch has proven to be a useful source of ancient DNA, both from humans and their microbiomes. Here we present the metagenomic analysis of three pieces of chewed pitch from Huseby Klev, Sweden, that were dated to 9,890-9,540 before present. The metagenomic profile exposes a Mesolithic oral microbiome that includes opportunistic oral pathogens. We compared the data with healthy and dysbiotic microbiome datasets and we identified increased abundance of periodontitis-associated microbes. In addition, trained machine learning models predicted dysbiosis with 70-80% probability. Moreover, we identified DNA sequences from eukaryotic species such as red fox, hazelnut, red deer and apple. Our results indicate a case of poor oral health during the Scandinavian Mesolithic, and show that pitch pieces have the potential to provide information on material use, diet and oral health.
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| 48. |
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| 49. |
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| 50. |
- Kjellström, Anna, 1970-, et al.
(författare)
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An Analysis of the Alleged Skeletal Remains of Carin Göring
- 2012
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Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 7:12, s. e44366-
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Tidskriftsartikel (refereegranskat)abstract
- In 1991, treasure hunters found skeletal remains in an area close to the destroyed country residence of former Nazi leader Hermann Goring in northeastern Berlin. The remains, which were believed to belong to Carin Goring, who was buried at the site, were examined to determine whether it was possible to make a positive identification. The anthropological analysis showed that the remains come from an adult woman. The DNA analysis of several bone elements showed female sex, and a reference sample from Carin's son revealed mtDNA sequences identical to the remains. The profile has one nucleotide difference from the Cambridge reference sequence ( rCRS), the common variant 263G. A database search resulted in a frequency of this mtDNA sequence of about 10% out of more than 7,000 European haplotypes. The mtDNA sequence found in the ulna, the cranium and the reference sample is, thus, very common among Europeans. Therefore, nuclear DNA analysis was attempted. The remains as well as a sample from Carin's son were successfully analysed for the three nuclear markers TH01, D7S820 and D8S1179. The nuclear DNA analysis of the two samples revealed one shared allele for each of the three markers, supporting a mother and son relationship. This genetic information together with anthropological and historical files provides an additional piece of circumstantial evidence in our efforts to identify the remains of Carin Goring.
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