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Sökning: WFRF:(Kornmann G)

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  • Glauser, T., et al. (författare)
  • Toughening of electron-beam cured acrylate resins
  • 2000
  • Ingår i: Macromolecular materials and engineering. - 1438-7492 .- 1439-2054. ; 280:08-jul, s. 20-25
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study was to improve the toughness of EB-cured acrylate thermost resins by using hyperbranched aliphatic polyesters as additives to obtain a liquid-liquid phase-separated resin. The hyperbranched polyester can be considered as a hydroxyl functional scaffold, on which functional groups were reacted by control phase separation and crosslinking. Alkyl chains of different lengths attached to the scaffold controlled phase separation. The amount of crosslinking within the rubbery particle and between the particles and the matrix was set by the percentage of methacrylate groups. A good phase separation was obtained; therefore, T-g decreased only slightly compared to the pure acrylate. The K-IC value of the cured resins was increased by 30%. The phase-separated resins showed stability with time and no significant increase in particle size was noticed after 18 months.
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  • Kanfer, G, et al. (författare)
  • Mitotic redistribution of the mitochondrial network by Miro and Cenp-F
  • 2015
  • Ingår i: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 6, s. 8015-
  • Tidskriftsartikel (refereegranskat)abstract
    • Although chromosome partitioning during mitosis is well studied, the molecular mechanisms that allow proper segregation of cytoplasmic organelles in human cells are poorly understood. Here we show that mitochondria interact with growing microtubule tips and are transported towards the daughter cell periphery at the end of mitosis. This phenomenon is promoted by the direct and cell cycle-dependent interaction of the mitochondrial protein Miro and the cytoskeletal-associated protein Cenp-F. Cenp-F is recruited to mitochondria by Miro at the time of cytokinesis and associates with microtubule growing tips. Cells devoid of Cenp-F or Miro show decreased spreading of the mitochondrial network as well as cytokinesis-specific defects in mitochondrial transport towards the cell periphery. Thus, Miro and Cenp-F promote anterograde mitochondrial movement and proper mitochondrial distribution in daughter cells.
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