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Sökning: WFRF:(Kumar Pravin)

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2.
  • Kumar, Pravin, et al. (författare)
  • Phylogenomic evaluation of Mangrovimicrobium sediminis gen. nov. sp. nov., the first nitrogen fixing member of the family Halieaceae adapted to mangrove habitat and reclassification of Halioglobus pacificus to Pseudohaliglobus pacificus comb. nov.
  • 2024
  • Ingår i: Science of the Total Environment. - : Elsevier. - 0048-9697 .- 1879-1026. ; 933
  • Tidskriftsartikel (refereegranskat)abstract
    • The taxonomic position and genomic characteristics of a nitrogen fixing and polymer degrading marine bacterium, strain SAOS 164 isolated from a mangrove sediment sample was investigated. Sequence analysis based on 16S rRNA gene identified it as a member of family Halieaceae with closest similarity to Haliea salexigens DSM 19537T (96.3 %), H. alexandrii LZ-16-2T (96.2 %) and Parahaliea maris HSLHS9T (96.0 %) but was distantly related to the genera Haliea, Parahaliea and Halioglobus in phylogenetic trees. In order to ascertain the exact taxonomic position, phylogeny based on RpoBC proteins, whole genome, core and orthologous genes, and comparative analysis of metabolic potential retrieved the strain in an independent lineage clustering along with the genera Halioglobus, Pseudohalioglobus and Seongchinamella. Further, various genome based delimitation parameters represented by mol % GC content, percentage of conserved proteins (POCP), and amino acid identity (AAI) along with chemotaxonomic markers (i.e. fatty acids and polar lipids) supported the inferences of genome based phylogeny and indicated that the strain SAOS 164 belongs to a novel genus. The genome was mapped to 4.8 Mb in size with 65.1 % DNA mol% G + C content. In-silico genomic investigation and phenotyping revealed diverse metabolite genes/pathways related to polymer hydrolysis, nitrogen fixation, light induced growth, carbohydrate, sulfur, phosphorus and amino acid metabolism, virulence factors, defense mechanism, and stress-responsive elements facilitating survival in the mangrove habitat. Based on polyphasic taxonomic approach including genome analyses, a novel genus Mangrovimicrobium sediminis gen. nov. sp. nov. (=SAOS 164T = MTCC 12907T = KCTC 52755T = JCM 32136T) is proposed. Additionally, the reclassification of Halioglobus pacificus (=DSM 27932T = KCTC 23430T = S1–72T) to Pseudhalioglobus pacificus comb. nov. is also proposed.
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3.
  • Rana, Pravin Kumar, et al. (författare)
  • Prediction of Sea Ice Edge in the Antarctic Using GVF Snake Model
  • 2011
  • Ingår i: Journal of the Geological Society of India. - : Springer Science and Business Media LLC. - 0016-7622 .- 0974-6889. ; 78:2, s. 99-108
  • Tidskriftsartikel (refereegranskat)abstract
    • Antarctic sea ice cover plays an important role in shaping the earth's climate, primarily by insulating the ocean from the atmosphere and increasing the surface albedo. The convective processes accompanied with the sea ice formation result bottom water formation. The cold and dense bottom water moves towards the equator along the ocean basins and takes part in the global thermohaline circulation. Sea ice edge is a potential indicator of climate change. Additionally, fishing and commercial shipping activities as well as military submarine operations in the polar seas need reliable ice edge information. However, as the sea ice edge is unstable in time, the temporal validity of the estimated ice edge is often shorter than the time required to transfer the information to the operational user. Hence, an accurate sea ice edge prediction as well as determination is crucial for fine-scale geophysical modeling and for near-real-time operations. In this study, active contour modelling (known as Snake model) and non-rigid motion estimation techniques have been used for predicting the sea ice edge (SIE) in the Antarctic. For this purpose the SIE has been detected from sea ice concentration derived using special sensor microwave imager (SSM/I) observations. The 15% sea ice concentration pixels are being taken as the edge pixel between ice and water. The external force, gradient vector flow (GVF), of SIE for total the Antarctic region is parameterised for daily as well as weekly data set. The SIE is predicted at certain points using a statistical technique. These predicted points have been used to constitute a SIE using artificial intelligence technique, the gradient vector flow (GVF). The predicted edge has been validated with that of SSM/I. It is found that all the major curvatures have been captured by the predicated edge and it is in good agreement with that of the SSM/I observation.
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4.
  • Ray, Sumit Kumar, et al. (författare)
  • Modern analogue to past coseismic ground uplift in North Andaman, India
  • 2021
  • Ingår i: Catena (Cremlingen. Print). - : Elsevier. - 0341-8162 .- 1872-6887. ; 205
  • Tidskriftsartikel (refereegranskat)abstract
    • Dynamics of surface geological processes, triggered by coseismic ground uplift following the 2004 Sumatra-Andaman earthquake (M-w > 9.2), provide a modern analogue for assessing the paleoseismic significance of an enigmatic subsurface peat occurrence within beach sands in the western coast of North Andaman Island. The megathrust earthquake uplifted vast stretches of coastal intertidal zones to supratidal levels. As a result, intertidal flora, including mangroves, desiccated and perished. Mass mortality of the flora continued even three years after the earthquake and generated a large volume of forest debris. Coastal waves pushed the debris to the high tide line where the accumulated debris would be gradually buried, and would subsequently transform into linear peat bodies keeping a record of the seismic event in 2004. Accordingly, we have interpreted a linear strand-parallel peat occurrence in beach sand as a record of earlier mass mortality of plants likely associated with a coseismic ground uplift. Stable isotope studies indicate that local intertidal flora is the source of the peat organic matter. Moreover, the 1817 CE calibrated mean AMS radiocarbon age of the peat suggests recurrence of a megathrust earthquake in the Andaman subduction zone about 200 years ago.
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5.
  • Georgakis, Apostolos, et al. (författare)
  • 3DTV Exploration Experiments (EE1 & EE4) on the Lovebird1 Data Set
  • 2009
  • Rapport (populärvet., debatt m.m.)abstract
    • This contribution describes the results to two sets of 3DTV exploration experiments undertaken by Ericsson using the Lovebird 1 sequence defined in the last MPEG meeting in London (see w10720). These sets cover both EE1 for depth estimation and view synthesis and EE4 for coding efficiency.
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8.
  • Granholm, Anders, et al. (författare)
  • Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia: a pre-planned, secondary Bayesian analysis of the COVID STEROID 2 trial
  • 2022
  • Ingår i: Intensive Care Medicine. - : SPRINGER. - 0342-4642 .- 1432-1238. ; 48:1, s. 45-55
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose We compared dexamethasone 12 versus 6 mg daily for up to 10 days in patients with coronavirus disease 2019 (COVID-19) and severe hypoxaemia in the international, randomised, blinded COVID STEROID 2 trial. In the primary, conventional analyses, the predefined statistical significance thresholds were not reached. We conducted a pre-planned Bayesian analysis to facilitate probabilistic interpretation. Methods We analysed outcome data within 90 days in the intention-to-treat population (data available in 967 to 982 patients) using Bayesian models with various sensitivity analyses. Results are presented as median posterior probabilities with 95% credible intervals (CrIs) and probabilities of different effect sizes with 12 mg dexamethasone. Results The adjusted mean difference on days alive without life support at day 28 (primary outcome) was 1.3 days (95% CrI -0.3 to 2.9; 94.2% probability of benefit). Adjusted relative risks and probabilities of benefit on serious adverse reactions was 0.85 (0.63 to 1.16; 84.1%) and on mortality 0.87 (0.73 to 1.03; 94.8%) at day 28 and 0.88 (0.75 to 1.02; 95.1%) at day 90. Probabilities of benefit on days alive without life support and days alive out of hospital at day 90 were 85 and 95.7%, respectively. Results were largely consistent across sensitivity analyses, with relatively low probabilities of clinically important harm with 12 mg on all outcomes in all analyses. Conclusion We found high probabilities of benefit and low probabilities of clinically important harm with dexamethasone 12 mg versus 6 mg daily in patients with COVID-19 and severe hypoxaemia on all outcomes up to 90 days.
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9.
  • Granholm, Anders, et al. (författare)
  • Higher vs Lower Doses of Dexamethasone in Patients with COVID-19 and Severe Hypoxia (COVID STEROID 2) trial: Protocol for a secondary Bayesian analysis
  • 2021
  • Ingår i: Acta Anaesthesiologica Scandinavica. - : WILEY. - 0001-5172 .- 1399-6576. ; 65:5, s. 702-710
  • Tidskriftsartikel (refereegranskat)abstract
    • Background Coronavirus disease 2019 (COVID-19) can lead to severe hypoxic respiratory failure and death. Corticosteroids decrease mortality in severely or critically ill patients with COVID-19. However, the optimal dose remains unresolved. The ongoing randomised COVID STEROID 2 trial investigates the effects of higher vs lower doses of dexamethasone (12 vs 6 mg intravenously daily for up to 10 days) in 1,000 adult patients with COVID-19 and severe hypoxia. Methods This protocol outlines the rationale and statistical methods for a secondary, pre-planned Bayesian analysis of the primary outcome (days alive without life support at day 28) and all secondary outcomes registered up to day 90. We will use hurdle-negative binomial models to estimate the mean number of days alive without life support in each group and present results as mean differences and incidence rate ratios with 95% credibility intervals (CrIs). Additional count outcomes will be analysed similarly and binary outcomes will be analysed using logistic regression models with results presented as probabilities, relative risks and risk differences with 95% CrIs. We will present probabilities of any benefit/harm, clinically important benefit/harm and probabilities of effects smaller than pre-defined clinically minimally important differences for all outcomes analysed. Analyses will be adjusted for stratification variables and conducted using weakly informative priors supplemented by sensitivity analyses using sceptic priors. Discussion This secondary, pre-planned Bayesian analysis will supplement the primary, conventional analysis and may help clinicians, researchers and policymakers interpret the results of the COVID STEROID 2 trial while avoiding arbitrarily dichotomised interpretations of the results. Trial registration ClinicalTrials.gov: NCT04509973; EudraCT: 2020-003363-25.
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10.
  • Granholm, Anders, et al. (författare)
  • Long-term outcomes of dexamethasone 12 mg versus 6 mg in patients with COVID-19 and severe hypoxaemia
  • 2022
  • Ingår i: Intensive Care Medicine. - : SPRINGER. - 0342-4642 .- 1432-1238. ; 48, s. 580-589
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose We assessed long-term outcomes of dexamethasone 12 mg versus 6 mg given daily for up to 10 days in patients with coronavirus disease 2019 (COVID-19) and severe hypoxaemia. Methods We assessed 180-day mortality and health-related quality of life (HRQoL) using EuroQoL (EQ)-5D-5L index values and EQ visual analogue scale (VAS) in the international, stratified, blinded COVID STEROID 2 trial, which randomised 1000 adults with confirmed COVID-19 receiving at least 10 L/min of oxygen or mechanical ventilation in 26 hospitals in Europe and India. In the HRQoL analyses, higher values indicated better outcomes, and deceased patients were given a score of zero. Results We obtained vital status at 180 days for 963 of 982 patients (98.1%) in the intention-to-treat population, EQ-5D-5L index value data for 922 (93.9%) and EQ VAS data for 924 (94.1%). At 180 days, 164 of 486 patients (33.7%) had died in the 12 mg group versus 184 of 477 (38.6%) in the 6 mg group [adjusted risk difference - 4.3%; 99% confidence interval (CI) - 11.7-3.0; relative risk 0.89; 0.72-1.09; P = 0.13]. The adjusted mean differences between the 12 mg and the 6 mg groups in EQ-5D-5L index values were 0.06 (99% CI - 0.01 to 0.12; P = 0.10) and in EQ VAS scores 4 (- 3 to 10; P = 0.22). Conclusion Among patients with COVID-19 and severe hypoxaemia, dexamethasone 12 mg compared with 6 mg did not result in statistically significant improvements in mortality or HRQoL at 180 days, but the results were most compatible with benefit from the higher dose.
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  • Kumar, Pravin, et al. (författare)
  • Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation
  • 2022
  • Ingår i: FEBS Letters. - : John Wiley & Sons. - 0014-5793 .- 1873-3468. ; 596:9, s. 1203-1213
  • Tidskriftsartikel (refereegranskat)abstract
    • Nonstructural protein 1 (Nsp1) of SARS-CoV-2 inhibits host cell translation through an interaction between its C-terminal domain and the 40S ribosome. The N-terminal domain (NTD) of Nsp1 is a target of recurring deletions, some of which are associated with altered COVID-19 disease progression. Here, we characterize the efficiency of translational inhibition by clinically observed Nsp1 deletion variants. We show that a frequent deletion of residues 79–89 severely reduces the ability of Nsp1 to inhibit translation while not abrogating Nsp1 binding to the 40S. Notably, while the SARS-CoV-2 5′ untranslated region enhances translation of mRNA, it does not protect from Nsp1-mediated inhibition. Finally, thermal stability measurements and structure predictions reveal a correlation between stability of the NTD and the efficiency of translation inhibition.
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12.
  • Laurent, Timothée, et al. (författare)
  • Architecture of the chikungunya virus replication organelle
  • 2022
  • Ingår i: eLIFE. - : eLife Sciences Publications. - 2050-084X. ; 11
  • Tidskriftsartikel (refereegranskat)abstract
    • Alphaviruses are mosquito-borne viruses that cause serious disease in humans and other mammals. Along with its mosquito vector, the Alphavirus chikungunya virus (CHIKV) has spread explosively in the last 20 years, and there is no approved treatment for chikungunya fever. On the plasma membrane of the infected cell, CHIKV generates dedicated organelles for viral RNA replication, so-called spherules. Whereas structures exist for several viral proteins that make up the spherule, the architecture of the full organelle is unknown. Here, we use cryo-electron tomography to image CHIKV spherules in their cellular context. This reveals that the viral protein nsP1 serves as a base for the assembly of a larger protein complex at the neck of the membrane bud. Biochemical assays show that the viral helicase-protease nsP2, while having no membrane affinity on its own, is recruited to membranes by nsP1. The tomograms further reveal that full-sized spherules contain a single copy of the viral genome in double-stranded form. Finally, we present a mathematical model that explains the membrane remodeling of the spherule in terms of the pressure exerted on the membrane by the polymerizing RNA, which provides a good agreement with the experimental data. The energy released by RNA polymerization is found to be sufficient to remodel the membrane to the characteristic spherule shape.
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  • Ma, Zhanyu, et al. (författare)
  • Bayesian estimation of Dirichlet mixture model with variational inference
  • 2014
  • Ingår i: Pattern Recognition. - : Elsevier BV. - 0031-3203 .- 1873-5142. ; 47:9, s. 3143-3157
  • Tidskriftsartikel (refereegranskat)abstract
    • In statistical modeling, parameter estimation is an essential and challengeable task. Estimation of the parameters in the Dirichlet mixture model (DMM) is analytically intractable, due to the integral expressions of the gamma function and its corresponding derivatives. We introduce a Bayesian estimation strategy to estimate the posterior distribution of the parameters in DMM. By assuming the gamma distribution as the prior to each parameter, we approximate both the prior and the posterior distribution of the parameters with a product of several mutually independent gamma distributions. The extended factorized approximation method is applied to introduce a single lower-bound to the variational objective function and an analytically tractable estimation solution is derived. Moreover, there is only one function that is maximized during iterations and, therefore, the convergence of the proposed algorithm is theoretically guaranteed. With synthesized data, the proposed method shows the advantages over the EM-based method and the previously proposed Bayesian estimation method. With two important multimedia signal processing applications, the good performance of the proposed Bayesian estimation method is demonstrated.
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14.
  • Munch, Marie W., et al. (författare)
  • Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia The COVID STEROID 2 Randomized Trial
  • 2021
  • Ingår i: Journal of the American Medical Association (JAMA). - : AMER MEDICAL ASSOC. - 0098-7484 .- 1538-3598. ; 326:18, s. 1807-1817
  • Tidskriftsartikel (refereegranskat)abstract
    • Question What is the effect of 12 mg vs 6 mg of dexamethasone on the number of days alive without life support at 28 days in patients with COVID-19 and severe hypoxemia? Findings In this randomized trial that included 1000 patients with COVID-19 and severe hypoxemia, treatment with 12 mg/d of dexamethasone resulted in 22.0 days alive without life support at 28 days compared with 20.5 days in those receiving 6 mg/d of dexamethasone. This difference was not statistically significant. Meaning Compared with 6 mg of dexamethasone, 12 mg of dexamethasone did not statistically significantly reduce the number of days alive without life support at 28 days. This multicenter randomized clinical trial compares the effects of 12 mg/d vs 6 mg/d of dexamethasone in patients with COVID-19 and severe hypoxemia. IMPORTANCE A daily dose with 6 mg of dexamethasone is recommended for up to 10 days in patients with severe and critical COVID-19, but a higher dose may benefit those with more severe disease. OBJECTIVE To assess the effects of 12 mg/d vs 6 mg/d of dexamethasone in patients with COVID-19 and severe hypoxemia. DESIGN, SETTING, AND PARTICIPANTS A multicenter, randomized clinical trial was conducted between August 2020 and May 2021 at 26 hospitals in Europe and India and included 1000 adults with confirmed COVID-19 requiring at least 10 L/min of oxygen or mechanical ventilation. End of 90-day follow-up was on August 19, 2021. INTERVENTIONS Patients were randomized 1:1 to 12 mg/d of intravenous dexamethasone (n = 503) or 6 mg/d of intravenous dexamethasone (n = 497) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was the number of days alive without life support (invasive mechanical ventilation, circulatory support, or kidney replacement therapy) at 28 days and was adjusted for stratification variables. Of the 8 prespecified secondary outcomes, 5 are included in this analysis (the number of days alive without life support at 90 days, the number of days alive out of the hospital at 90 days, mortality at 28 days and at 90 days, and >= 1 serious adverse reactions at 28 days). RESULTS Of the 1000 randomized patients, 982 were included (median age, 65 [IQR, 55-73] years; 305 [31%] women) and primary outcome data were available for 971 (491 in the 12 mg of dexamethasone group and 480 in the 6 mg of dexamethasone group). The median number of days alive without life support was 22.0 days (IQR, 6.0-28.0 days) in the 12 mg of dexamethasone group and 20.5 days (IQR, 4.0-28.0 days) in the 6 mg of dexamethasone group (adjusted mean difference, 1.3 days [95% CI, 0-2.6 days]; P = .07). Mortality at 28 days was 27.1% in the 12 mg of dexamethasone group vs 32.3% in the 6 mg of dexamethasone group (adjusted relative risk, 0.86 [99% CI, 0.68-1.08]). Mortality at 90 days was 32.0% in the 12 mg of dexamethasone group vs 37.7% in the 6 mg of dexamethasone group (adjusted relative risk, 0.87 [99% CI, 0.70-1.07]). Serious adverse reactions, including septic shock and invasive fungal infections, occurred in 11.3% in the 12 mg of dexamethasone group vs 13.4% in the 6 mg of dexamethasone group (adjusted relative risk, 0.83 [99% CI, 0.54-1.29]). CONCLUSIONS AND RELEVANCE Among patients with COVID-19 and severe hypoxemia, 12 mg/d of dexamethasone compared with 6 mg/d of dexamethasone did not result in statistically significantly more days alive without life support at 28 days. However, the trial may have been underpowered to identify a significant difference.
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15.
  • Munch, Marie Warrer, et al. (författare)
  • Higher vs lower doses of dexamethasone in patients with COVID-19 and severe hypoxia (COVID STEROID 2) trial : Protocol and statistical analysis plan
  • 2021
  • Ingår i: Acta Anaesthesiologica Scandinavica. - : WILEY. - 0001-5172 .- 1399-6576. ; 65:6, s. 834-845
  • Tidskriftsartikel (refereegranskat)abstract
    • Background The coronavirus disease 2019 (COVID-19) pandemic has resulted in millions of deaths and overburdened healthcare systems worldwide. Systemic low-dose corticosteroids have proven clinical benefit in patients with severe COVID-19. Higher doses of corticosteroids are used in other inflammatory lung diseases and may offer additional clinical benefits in COVID-19. At present, the balance between benefits and harms of higher vs. lower doses of corticosteroids for patients with COVID-19 is unclear. Methods The COVID STEROID 2 trial is an investigator-initiated, international, parallel-grouped, blinded, centrally randomised and stratified clinical trial assessing higher (12 mg) vs. lower (6 mg) doses of dexamethasone for adults with COVID-19 and severe hypoxia. We plan to enrol 1,000 patients in Denmark, Sweden, Switzerland and India. The primary outcome is days alive without life support (invasive mechanical ventilation, circulatory support or renal replacement therapy) at day 28. Secondary outcomes include serious adverse reactions at day 28; all-cause mortality at day 28, 90 and 180; days alive without life support at day 90; days alive and out of hospital at day 90; and health-related quality of life at day 180. The primary outcome will be analysed using the Kryger Jensen and Lange test adjusted for stratification variables and reported as adjusted mean differences and median differences. The full statistical analysis plan is outlined in this protocol. Discussion The COVID STEROID 2 trial will provide evidence on the optimal dosing of systemic corticosteroids for COVID-19 patients with severe hypoxia with important implications for patients, their relatives and society.
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  • Parthasarathy, Srinivas, et al. (författare)
  • Denoising of volumetric depth confidence for view rendering
  • 2012
  • Ingår i: 3DTV-Conference: The True Vision - Capture, Transmission and Display of 3D Video (3DTV-CON), 2012. - : IEEE. - 9781467349055 ; , s. 1-4
  • Konferensbidrag (refereegranskat)abstract
    • In this paper, we define volumetric depth confidence and propose a method to denoise this data by performing adaptive wavelet thresholding using three dimensional (3D) wavelet transforms. The depth information is relevant for emerging interactive multimedia applications such as 3D TV and free-viewpoint television (FTV). These emerging applications require high quality virtual view rendering to enable viewers to move freely in a dynamic real worldscene. Depth information of a real world scene from different viewpoints is used to render an arbitrary number of novel views. Usually, depth estimates of 3D object points from different viewpoints are inconsistent. This inconsistency of depth estimates affects the quality of view rendering negatively. Based on the superposition principle, we define a volumetric depth confidence description of the underlying geometry of natural 3D scenes by using these inconsistent depth estimates from different viewpoints. Our method denoises this noisy volumetric description, and with this, we enhance the quality of view rendering by up to 0.45 dB when compared to rendering with conventional MPEG depth maps.
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  • Rana, Pravin Kumar, 1982-, et al. (författare)
  • A Variational Bayesian Inference Framework for Multiview Depth Image Enhancement
  • 2012
  • Ingår i: Proceedings - 2012 IEEE International Symposium on Multimedia, ISM 2012. - : IEEE. - 9780769548753 ; , s. 183-190
  • Konferensbidrag (refereegranskat)abstract
    • In this paper, a general model-based framework for multiview depth image enhancement is proposed. Depth imagery plays a pivotal role in emerging free-viewpoint television. This technology requires high quality virtual view synthesis to enable viewers to move freely in a dynamic real world scene. Depth imagery of different viewpoints is used to synthesize an arbitrary number of novel views. Usually, the depth imagery is estimated individually by stereo-matching algorithms and, hence, shows lack of inter-view consistency. This inconsistency affects the quality of view synthesis negatively. This paper enhances the inter-view consistency of multiview depth imagery by using a variational Bayesian inference framework. First, our approach classifies the color information in the multiview color imagery. Second, using the resulting color clusters, we classify the corresponding depth values in the multiview depth imagery. Each clustered depth image is subject to further subclustering. Finally, the resulting mean of the sub-clusters is used to enhance the depth imagery at multiple viewpoints. Experiments show that our approach improves the quality of virtual views by up to 0.25 dB.
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18.
  • Rana, Pravin Kumar, 1982-, et al. (författare)
  • Depth consistency testing for improved view interpolation
  • 2010
  • Ingår i: <em></em>. - 9781424481118 ; , s. 384-389
  • Konferensbidrag (refereegranskat)abstract
    • Multiview video will play a pivotal role in the next generation visual communication media services like three-dimensional (3D) television and free-viewpoint television. These advanced media services provide natural 3D impressions and enable viewers to move freely in a dynamic real world scene by changing the viewpoint. High quality virtual view interpolation is required to support free viewpoint viewing. Usually, depth maps of different viewpoints are used to reconstruct a novel view. As these depth maps are usually estimated individually by stereo-matching algorithms, they have very weak spatial consistency. The inconsistency of depth maps affects the quality of view interpolation. In this paper, we propose a method for depth consistency testing to improve view interpolation. The method addresses the problem by warping more than two depth maps from multiple reference viewpoints to the virtual viewpoint. We test the consistency among warped depth values and improve the depth value information of the virtual view. With that, we enhance the quality of the interpolated virtual view.
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  • Rana, Pravin Kumar, 1982-, et al. (författare)
  • Depth Pixel Clustering for Consistency Testing of Multiview Depth
  • 2012
  • Ingår i: European Signal Processing Conference. - 9781467310680 ; , s. 1119-1123
  • Konferensbidrag (refereegranskat)abstract
    • This paper proposes a clustering algorithm of depth pixels for consistency testing of multiview depth imagery. The testing addresses the inconsistencies among estimated depth maps of real world scenes by validating depth pixel connection evidence based on a hard connection threshold. With the proposed algorithm, we test the consistency among depth values generated from multiple depth observations using cluster adaptive connection thresholds. The connection threshold is based on statistical properties of depth pixels in a cluster or sub-cluster. This approach can improve the depth information of real world scenes at a given viewpoint. This allows us to enhance the quality of synthesized virtual views when compared to depth maps obtained by using fixed thresholding. Depth-image-based virtual view synthesis is widely used for upcoming multimedia services like three-dimensional television and free-viewpoint television.
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20.
  • Rana, Pravin Kumar, 1982-, et al. (författare)
  • Multiview Depth Map Enhancement by Variational Bayes Inference Estimation of Dirichlet Mixture Models
  • 2013
  • Ingår i: 2013 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP). - : IEEE. - 9781479903566 ; , s. 1528-1532
  • Konferensbidrag (refereegranskat)abstract
    • High quality view synthesis is a prerequisite for future free-viewpointtelevision. It will enable viewers to move freely in a dynamicreal world scene. Depth image based rendering algorithms willplay a pivotal role when synthesizing an arbitrary number of novelviews by using a subset of captured views and corresponding depthmaps only. Usually, each depth map is estimated individually bystereo-matching algorithms and, hence, shows lack of inter-viewconsistency. This inconsistency affects the quality of view synthesis negatively. This paper enhances the inter-view consistency ofmultiview depth imagery. First, our approach classifies the colorinformation in the multiview color imagery by modeling color witha mixture of Dirichlet distributions where the model parameters areestimated in a Bayesian framework with variational inference. Second, using the resulting color clusters, we classify the correspondingdepth values in the multiview depth imagery. Each clustered depthimage is subject to further sub-clustering. Finally, the resultingmean of each sub-cluster is used to enhance the depth imagery atmultiple viewpoints. Experiments show that our approach improvesthe average quality of virtual views by up to 0.8 dB when comparedto views synthesized by using conventionally estimated depth maps.
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21.
  • Rana, Pravin Kumar, et al. (författare)
  • Probabilistic Multiview Depth Image Enhancement Using Variational Inference
  • 2015
  • Ingår i: IEEE Journal on Selected Topics in Signal Processing. - 1932-4553 .- 1941-0484. ; 9:3, s. 435-448
  • Tidskriftsartikel (refereegranskat)abstract
    • An inference-based multiview depth image enhancement algorithm is introduced and investigated in this paper. Multiview depth imagery plays a pivotal role in free-viewpoint television. This technology requires high-quality virtual view synthesis to enable viewers to move freely in a dynamic real world scene. Depth imagery of different viewpoints is used to synthesize an arbitrary number of novel views. Usually, the depth imagery is estimated individually by stereo-matching algorithms and, hence, shows inter-view inconsistency. This inconsistency affects the quality of view synthesis negatively. This paper enhances the multiview depth imagery at multiple viewpoints by probabilistic weighting of each depth pixel. First, our approach classifies the color pixels in the multiview color imagery. Second, using the resulting color clusters, we classify the corresponding depth values in the multiview depth imagery. Each clustered depth image is subject to further subclustering. Clustering based on generative models is used for assigning probabilistic weights to each depth pixel. Finally, these probabilistic weights are used to enhance the depth imagery at multiple viewpoints. Experiments show that our approach consistently improves the quality of virtual views by 0.2 dB to 1.6 dB, depending on the quality of the input multiview depth imagery.
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22.
  • Rana, Pravin Kumar, et al. (författare)
  • Statistical methods for inter-view depth enhancement
  • 2014
  • Ingår i: 2014 3DTV-Conference. - : IEEE. - 9781479947584 ; , s. 6874755-
  • Konferensbidrag (refereegranskat)abstract
    • This paper briefly presents and evaluates recent advances in statistical methods for improving inter-view inconsistency in multiview depth imagery. View synthesis is vital in free-viewpoint television in order to allow viewers to move freely in a dynamic scene. Here, depth image-based rendering plays a pivotal role by synthesizing an arbitrary number of novel views by using a subset of captured views and corresponding depth maps only. Usually, each depth map is estimated individually at different viewpoints by stereo matching and, hence, shows lack of inter-view consistency. This lack of consistency affects the quality of view synthesis negatively. This paper discusses two different approaches to enhance the inter-view depth consistency. The first one uses generative models based on multiview color and depth classification to assign a probabilistic weight to each depth pixel. The weighted depth pixels are utilized to enhance depth maps. The second one performs inter-view consistency testing in depth difference space to enhance the depth maps at multiple viewpoints. We comparatively evaluate these two methods and discuss their pros and cons for future work.
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24.
  • Rana, Pravin Kumar, 1982-, et al. (författare)
  • View Interpolation with structured depth from multiview video
  • 2011
  • Konferensbidrag (refereegranskat)abstract
    • In this paper, we propose a method for interpolating multiview imagery which uses structured depth maps and multiview video plus inter-view connection information to represent a three-dimensional (3D) scene. The structured depth map consists of an inter-view consistent principal depth map and auxiliary depth information. The structured depth maps address the inconsistencies among estimated depth maps which may degrade the quality of rendered virtual views. Generated from multiple depth observations, the structuring of the depth maps is based on tested and adaptively chosen inter-view connections. Further, the use of connection information on the multiview video minimizes distortion due to varying illumination in the interpolated virtual views. Our approach improves the quality of rendered virtual views by up to 4 dB when compared to the reference MPEG view synthesis software for emerging multimedia services like 3D television and free-viewpoint television. Our approach obtains first the structured depth maps and the corresponding connection information. Second, it exploits the inter-view connection information when interpolating virtual views.
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