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- Al-Khafaji, Q A M, et al.
(författare)
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An Electrochemical Immunoassay for HER2 Detection
- 2012
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Ingår i: Electroanalysis. - : Wiley-VCH Verlag Berlin. - 1040-0397 .- 1521-4109. ; 24:4, s. 735-742
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Tidskriftsartikel (refereegranskat)abstract
- In this paper, a simple and sensitive approach for human epidermal growth factor receptor 2 (HER2) detection is presented, using antibody-functionalised magnetic beads coupled to screen-printed cells. The immunoassay is based on a sandwich format in which a primary monoclonal antibody anti-HER2 is coupled to protein A modified magnetic beads. The modified beads are then used to capture the protein from the sample solution and a sandwich assay is performed by adding a secondary monoclonal antibody anti-HER2 labelled with biotin. The enzyme alkaline phosphatase (AP) conjugated with streptavidin and its substrate (1-naphthyl-phosphate) are then used for the electrochemical detection by differential pulse voltammetry (DPV). The experimental conditions for the immunoassay were optimised. The performance of the assay in terms of sensitivity, reproducibility and selectivity has been studied in buffer and serum samples from hospital patients.
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| 2. |
- Laschi, Cecilia, et al.
(författare)
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A Bio-inspired Neural Sensory-Motor Coordination Scheme for Robot Reaching and Preshaping
- 2006
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Ingår i: Proceedings of the First IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics : BioRob 2006. - Piscataway, NJ : IEEE. - 1424400406 ; , s. 531-536
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- We present a sensory-motor coordination scheme for a robot hand-arm-head system that provides the robot with the capability to reach for and to grasp an object, while pre-shaping the fingers to the required grasp configuration. A model for sensory-motor coordination derived from studies in humans inspired the development of the scheme. A special feature of this model is the prediction of the tactile image perceived after grasping. The proposed scheme is based on a neuro-fuzzy modnle that, after a learning phase, starting from visual data, calculates the position and orientation of the hand for grasping, selects the best-suited hand configuration, and predicts the tactile feedback after grasping. The implementation of the scheme on a humanoid robot ailowed experimental validation of its effectiveness in robotics and provided perspectives on applications of sensory predictions in robot motor control.
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| 3. |
- Laschi, Cecilia, et al.
(författare)
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Bio-inspired sensory-motor coordination
- 2008
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Ingår i: Autonomous Robots. - : Springer. - 0929-5593 .- 1573-7527. ; 25:1-2, s. 1-2
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Tidskriftsartikel (refereegranskat)
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| 8. |
- Pinpin, Lord Kenneth, et al.
(författare)
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Utilizing gaze behavior for inferring task transitions using abstract hidden markov models
- 2016
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Ingår i: Inteligencia Artificial. Ibero-American Journal of Artificial Intelligence. - : IBERAMIA: Sociedad Iberoamericana de Inteligencia Artificial. - 1137-3601 .- 1988-3064. ; 19:58, s. 1-16
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Tidskriftsartikel (refereegranskat)abstract
- We demonstrate an improved method for utilizing observed gaze behavior and show that it is useful in inferring hand movement intent during goal directed tasks. The task dynamics and the relationship between hand and gaze behavior are learned using an Abstract Hidden Markov Model (AHMM). We show that the predicted hand movement transitions occur consistently earlier in AHMM models with gaze than those models that do not include gaze observations.
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