| 1. |
- Wienhold, P., et al.
(författare)
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Exposure of metal mirrors in the scrape-off layer of TEXTOR
- 2005
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Ingår i: Journal of Nuclear Materials. - : Elsevier BV. - 0022-3115 .- 1873-4820. ; 337-39:03-jan, s. 1116-1120
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Tidskriftsartikel (refereegranskat)abstract
- Large molybdenum mirrors have been exposed in the SOL of TEXTOR in order to simulate conditions relevant for ITER optical components. Distortions of the reflectivity - increase as well as decrease - are found in the erosion and deposition dominated areas, respectively. The changes are most pronounced in the near UV and level off in the IR and can partly be attributed to observed surface changes. A novel periscope system was installed and mirrors exposed in a pilot experiment to simulate the transmission of light to distant sensors in ITER.
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| 2. |
- Delhom, Robin, et al.
(författare)
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The Antifungal Mechanism of Amphotericin B Elucidated in Ergosterol and Cholesterol-Containing Membranes Using Neutron Reflectometry
- 2020
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Ingår i: Nanomaterials. - : MDPI AG. - 2079-4991. ; 10:12
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Tidskriftsartikel (refereegranskat)abstract
- We have characterized and compared the structures of ergosterol- and cholesterol-containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes before and after interaction with the amphiphilic antifungal drug amphotericin B (AmB) using neutron reflection. AmB inserts into both pure POPC and sterol-containing membranes in the lipid chain region and does not significantly perturb the structure of pure POPC membranes. By selective per-deuteration of the lipids/sterols, we show that AmB extracts ergosterol but not cholesterol from the bilayers and inserts to a much higher degree in the cholesterol-containing membranes. Ergosterol extraction by AmB is accompanied by membrane thinning. Our results provide new insights into the mechanism and antifungal effect of AmB in these simple models of fungal and mammalian membranes and help understand the molecular origin of its selectivity and toxic side effects.
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| 3. |
- Laux, M., et al.
(författare)
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Arcing at B4C-covered limiters exposed to a SOL-plasma
- 2003
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Ingår i: Journal of Nuclear Materials. - 0022-3115 .- 1873-4820. ; 313, s. 62-66
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Tidskriftsartikel (refereegranskat)abstract
- Plasma sprayed B4C-layers considered as wall coatings for the W7X stellarator have been studied during and after exposure to TEXTOR and after arcing experiments in vacuum. Arcing through the B4C layer occurred favoured by high power fluxes and not restricted to less stable phases. But this arcing implies an especially noisy scrape-off layer (SOL). Instead of moving retrograde in the external magnetic field, the arc spot on the B4C-layer sticks to the same location for its whole lifetime. Consequently, the arc erodes the entire B4C layer, finally burning down to the Cu substrate. In the neighbourhood of craters the surface contains Cu originating from those craters. This material, hauled to the surface by the arc, is subject to subsequent erosion, transport, and redeposition by the SOL-plasma. The behaviour of arcs on B4C is Most probably caused by the peculiar temperature dependences of the electrical and heat conductivity of B4C.
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