| 1. |
- Lennartsson, Jan, 1981, et al.
(författare)
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Game intelligence in team sports
- 2015
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Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 10:5
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Tidskriftsartikel (refereegranskat)abstract
- We set up a game theoretic framework to analyze a wide range of situations from team sports. A fundamental idea is the concept of potential ; the probability of the offense scoring the next goal minus the probability that the next goal is made by the defense. We develop categorical as well as continuous models, and obtain optimal strategies for both offense and defense. A main result is that the optimal defensive strategy is to minimize the maximum potential of all offensive strategies.
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| 2. |
- Anselm, Jonas, et al.
(författare)
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Bannlys alla politiska beslut som ger mer klimatutsläpp
- 2014
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Ingår i: Dagens Nyheter.
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Torftig valdebatt. Dagspolitiken klarar inte att hantera ödesfrågan om klimatet, vilket oroar oss. Vi föreslår därför ett ”utsläppsmoratorium”: inga beslut får tas som ökar utsläppen av växthusgaser. Principen måste kopplas till mål om exempelvis förnybar energi och grön infrastruktur, skriver 23 forskare och debattörer.
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| 3. |
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| 4. |
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| 5. |
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| 6. |
- Bergström, Göran, 1964, et al.
(författare)
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Prevalence of Subclinical Coronary Artery Atherosclerosis in the General Population
- 2021
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Ingår i: Circulation. - Philadelphia : American Heart Association. - 0009-7322 .- 1524-4539. ; 144:12, s. 916-929
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Tidskriftsartikel (refereegranskat)abstract
- Background: Early detection of coronary atherosclerosis using coronary computed tomography angiography (CCTA), in addition to coronary artery calcification (CAC) scoring, may help inform prevention strategies. We used CCTA to determine the prevalence, severity, and characteristics of coronary atherosclerosis and its association with CAC scores in a general population.Methods: We recruited 30 154 randomly invited individuals age 50 to 64 years to SCAPIS (the Swedish Cardiopulmonary Bioimage Study). The study includes individuals without known coronary heart disease (ie, no previous myocardial infarctions or cardiac procedures) and with high-quality results from CCTA and CAC imaging performed using dedicated dual-source CT scanners. Noncontrast images were scored for CAC. CCTA images were visually read and scored for coronary atherosclerosis per segment (defined as no atherosclerosis, 1% to 49% stenosis, or ≥50% stenosis). External validity of prevalence estimates was evaluated using inverse probability for participation weighting and Swedish register data.Results: In total, 25 182 individuals without known coronary heart disease were included (50.6% women). Any CCTA-detected atherosclerosis was found in 42.1%; any significant stenosis (≥50%) in 5.2%; left main, proximal left anterior descending artery, or 3-vessel disease in 1.9%; and any noncalcified plaques in 8.3% of this population. Onset of atherosclerosis was delayed on average by 10 years in women. Atherosclerosis was more prevalent in older individuals and predominantly found in the proximal left anterior descending artery. Prevalence of CCTA-detected atherosclerosis increased with increasing CAC scores. Among those with a CAC score >400, all had atherosclerosis and 45.7% had significant stenosis. In those with 0 CAC, 5.5% had atherosclerosis and 0.4% had significant stenosis. In participants with 0 CAC and intermediate 10-year risk of atherosclerotic cardiovascular disease according to the pooled cohort equation, 9.2% had CCTA-verified atherosclerosis. Prevalence estimates had excellent external validity and changed marginally when adjusted to the age-matched Swedish background population.Conclusions: Using CCTA in a large, random sample of the general population without established disease, we showed that silent coronary atherosclerosis is common in this population. High CAC scores convey a significant probability of substantial stenosis, and 0 CAC does not exclude atherosclerosis, particularly in those at higher baseline risk.
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| 7. |
- Bergström, Göran, et al.
(författare)
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Prevalence of Subclinical Coronary Artery Atherosclerosis in the General Population
- 2021
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Ingår i: Circulation. - : Wolters Kluwer. - 0009-7322 .- 1524-4539. ; 144:12, s. 916-929
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Tidskriftsartikel (refereegranskat)abstract
- Background: Early detection of coronary atherosclerosis using coronary computed tomography angiography (CCTA), in addition to coronary artery calcification (CAC) scoring, may help inform prevention strategies. We used CCTA to determine the prevalence, severity, and characteristics of coronary atherosclerosis and its association with CAC scores in a general population.Methods: We recruited 30 154 randomly invited individuals age 50 to 64 years to SCAPIS (the Swedish Cardiopulmonary Bioimage Study). The study includes individuals without known coronary heart disease (ie, no previous myocardial infarctions or cardiac procedures) and with high-quality results from CCTA and CAC imaging performed using dedicated dual-source CT scanners. Noncontrast images were scored for CAC. CCTA images were visually read and scored for coronary atherosclerosis per segment (defined as no atherosclerosis, 1% to 49% stenosis, or ≥50% stenosis). External validity of prevalence estimates was evaluated using inverse probability for participation weighting and Swedish register data.Results: In total, 25 182 individuals without known coronary heart disease were included (50.6% women). Any CCTA-detected atherosclerosis was found in 42.1%; any significant stenosis (≥50%) in 5.2%; left main, proximal left anterior descending artery, or 3-vessel disease in 1.9%; and any noncalcified plaques in 8.3% of this population. Onset of atherosclerosis was delayed on average by 10 years in women. Atherosclerosis was more prevalent in older individuals and predominantly found in the proximal left anterior descending artery. Prevalence of CCTA-detected atherosclerosis increased with increasing CAC scores. Among those with a CAC score >400, all had atherosclerosis and 45.7% had significant stenosis. In those with 0 CAC, 5.5% had atherosclerosis and 0.4% had significant stenosis. In participants with 0 CAC and intermediate 10-year risk of atherosclerotic cardiovascular disease according to the pooled cohort equation, 9.2% had CCTA-verified atherosclerosis. Prevalence estimates had excellent external validity and changed marginally when adjusted to the age-matched Swedish background population.Conclusions: Using CCTA in a large, random sample of the general population without established disease, we showed that silent coronary atherosclerosis is common in this population. High CAC scores convey a significant probability of substantial stenosis, and 0 CAC does not exclude atherosclerosis, particularly in those at higher baseline risk.
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| 8. |
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| 9. |
- Malinovschi, Andrei, 1978-, et al.
(författare)
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Consequences of Using Post- or Prebronchodilator Reference Values in Interpreting Spirometry
- 2023
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Ingår i: American Journal of Respiratory and Critical Care Medicine. - : American Thoracic Society. - 1073-449X .- 1535-4970. ; 208:4, s. 461-471
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Tidskriftsartikel (refereegranskat)abstract
- RATIONALE: Post-bronchodilator (BD) spirometry is used for diagnosis of chronic obstructive pulmonary disease (COPD). However, pre-BD reference values are used for spirometry interpretation.OBJECTIVES: To compare the resulting prevalence rates of abnormal spirometry and study the consequences of using pre- or post-BD reference values generated within the Swedish CArdioPulmonary bioImage Study (SCAPIS) when interpreting post-BD spirometry in a general population.METHODS: SCAPIS reference values for post-BD and pre-BD spirometry were based on 10,156 and 1,498 never-smoking, healthy participants, respectively. We studied the associations of abnormal spirometry, defined by using pre- or post-BD reference values, with respiratory burden in the SCAPIS general population (28,851 individuals).MEASUREMENTS AND MAIN RESULTS: Bronchodilation resulted in higher predicted median and lower limit of normal (LLN) for FEV1/FVC ratio. The prevalence of post-BD FEV1/FVC < pre-bronchodilator LLN was 4.8% and that of post-BD FEV1/FVC < post-bronchodilator LLN was 9.9% for the general population. An additional 5.1% was identified as having an abnormal post-BD FEV1/FVC ratio and this group had more respiratory symptoms, emphysema (13.5% vs. 4.1%, p<0.001) and self-reported physician-diagnosed COPD (2.8% vs. 0.5%, p<0.001) than subjects with post-BD FEV1/FVC ratio > LLN for both pre- and post-bronchodilation).CONCLUSIONS: Pre- and post-bronchodilator spirometry reference values differ with regard to FEV1/FVC ratio. Use of post-bronchodilator reference values doubled the population prevalence of airflow obstruction; this was related to a higher respiratory burden. Using post-bronchodilator reference values when interpreting post-bronchodilator spirometry might enable identification of individuals with mild disease and be clinically relevant.
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| 10. |
- Torén, Kjell, 1952, et al.
(författare)
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Chronic airflow limitation and its relation to respiratory symptoms among ever-smokers and never-smokers: a cross-sectional study
- 2020
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Ingår i: Bmj Open Respiratory Research. - : BMJ. - 2052-4439. ; 7:1
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Tidskriftsartikel (refereegranskat)abstract
- Background The diagnosis of chronic obstructive pulmonary disease is based on the presence of persistent respiratory symptoms and chronic airflow limitation (CAL). CAL is based on the ratio of forced expiratory volume in 1 s to forced vital capacity (FEV1:FVC) after bronchodilation, and FEV1:FVC less than the fifth percentile is often used as a cut-off for CAL. The aim was to investigate if increasing percentiles of FEV1:FVC were associated withany respiratory symptom(cough with phlegm, dyspnoea or wheezing) in a general population sample of never-smokers and ever-smokers. Methods In a cross-sectional study comprising 15 128 adults (50-64 years), 7120 never-smokers and 8008 ever-smokers completed a respiratory questionnaire and performed FEV(1)and FVC after bronchodilation. We calculated theirz-scores for FEV1:FVC and defined the fifth percentile using the Global Lung Function Initiative (GLI) reference value, GLI(5)and increasing percentiles up to GLI(25). We analysed the associations between different strata of percentiles and prevalence ofany respiratory symptomusing multivariable logistic regression for estimation of OR. Results Among all subjects, regardless of smoking habits, the odds ofany respiratory symptomwere elevated up to the GLI(15-20)strata. Among never-smokers, the odds ofany respiratory symptomwere elevated at GLI(<5)(OR 3.57, 95% CI 2.43 to 5.23) and at GLI(5-10)(OR 2.57, 95% CI 1.69 to 3.91), but not at higher percentiles. Among ever-smokers, the odds ofany respiratory symptomwere elevated from GLI(<5)(OR 4.64, 95% CI 3.79 to 5.68) up to GLI(>= 25)(OR 1.33, 95% CI 1.00 to 1.75). Conclusions The association between percentages of FEV1:FVC and respiratory symptoms differed depending on smoking history. Our results support a higher percentile cut-off for FEV1:FVC for never-smokers and, in particular, for ever-smokers.
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| 11. |
- Torén, Kjell, 1952, et al.
(författare)
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The ratio FEV1/FVC and its association to respiratory symptoms-A Swedish general population study
- 2021
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Ingår i: Clinical Physiology and Functional Imaging. - : Wiley. - 1475-0961 .- 1475-097X. ; 41:2, s. 181-191
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Tidskriftsartikel (refereegranskat)abstract
- Chronic airflow limitation (CAL) can be defined as fixed ratio of forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) any respiratory symptom. In a cross-sectional general population study, 15,128 adults (50-64 years of age), 7,120 never-smokers and 8,008 ever-smokers completed a respiratory questionnaire and performed FEV1 and FVC after bronchodilation. We calculated different ratios of FEV1/FVC from 0.40 to 1.0 using 0.70 as reference category. We analysed odds ratios (OR) between different ratios and any respiratory symptom using adjusted multivariable logistic regression. Among all subjects, regardless of smoking habits, the lowest odds for any respiratory symptom was at FEV1/FVC = 0.82, OR 0.48 (95% CI 0.41-0.56). Among never-smokers, the lowest odds for any respiratory symptom was at FEV1/FVC = 0.81, OR 0.53 (95% CI 0.41-0.70). Among ever-smokers, the odds for any respiratory symptom was lowest at FEV1/FVC = 0.81, OR 0.43 (95% CI 0.16-1.19), although the rate of inclining in odds was small in the upper part, that is FEV1/FVC = 0.85 showed similar odds, OR 0.45 (95% CI 0.38-0.55). We concluded that the odds for any respiratory symptoms continuously decreased with higher FEV1/FVC ratios and reached a minimum around 0.80-0.85, with similar results among never-smokers. These results indicate that the optimal threshold associated with respiratory symptoms may be higher than 0.70 and this should be further investigated in prospective longitudinal studies.
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| 12. |
- Adlerberth, Ingegerd, 1959, et al.
(författare)
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Toxin-producing Clostridium difficile strains as long-term gut colonizers of healthy infants.
- 2014
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Ingår i: Journal of clinical microbiology. - 1098-660X. ; 52:1, s. 173-179
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Tidskriftsartikel (refereegranskat)abstract
- Clostridium difficile is a colonizer of the human gut, and toxin-producing strains may cause diarrhea if infectious burden is heavy. Infants are more frequently colonized than adults, but rarely develop C. difficile disease. It is not known whether strains of C. difficile differ in capacity to colonize and persist in the human gut microbiota. Here, we strain-typed isolates of C. difficile colonizing 42 healthy infants followed from birth to ≥12 months of age, using PCR ribotyping of the 16S-23S rRNA intergenic spacer region. The isolates were also characterized regarding carriage of the toxin genes tcdA, tcdB and cdtA/B, and capacity to produce toxin B in vitro. Most strains (71%) were toxin-producers, and 51% belonged to the 001 or 014 ribotypes, that often cause disease in adults. These ribotypes were significantly more likely than other ones to persist for ≥6 months in the infant micobiota, and were isolated from 13/15 children carrying such long-term colonizing strains. Ribotype 001 strains were often acquired in the first week of life and attained higher population counts than other C. difficile ribotypes in newborn infants' faeces. Several toxin-negative ribotypes were identified, two of which (GI and GIII) were long-term colonizers, each in one infant. Our results suggest that the toxin-producing C. difficile ribotypes 001 and 014 have special fitness in the infantile gut microbiota. Toxin-producing strains colonizing young children for long time periods may represent a reservoir for strains causing disease in adults.
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| 13. |
- Alsterholm, Mikael, 1977, et al.
(författare)
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Establishment and utility of SwedAD : a nationwide Swedish registry for patients with atopic dermatitis receiving systemic pharmacotherapy
- 2023
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Ingår i: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 0001-5555 .- 1651-2057. ; 103
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Tidskriftsartikel (refereegranskat)abstract
- SwedAD, a Swedish nationwide registry for patients with atopic dermatitis receiving systemic pharmacotherapy, was launched on 1 September 2019. We describe here the establishment of a user-friendly registry to the benefit of patients with atopic dermatitis. By 5 November 2022, 38 clinics had recorded 931 treatment episodes in 850 patients with an approximate national coverage rate of 40%. Characteristics at enrolment included median Eczema Area and Severity Index (EASI) 10.2 (interquartile range 4.0, 19.4), Patient-Oriented Eczema Measure (POEM) 18.0 (10.0, 24.0), Dermatology Life Quality Index (DLQI) 11.0 (5.0, 19.0) and Peak Itch Numerical Rating Scale-11 (NRS-11) 6.0 (3.0, 8.0). At 3 months, median EASI was 3.2 (1.0, 7.3) and POEM, DLQI, and NRS-11 were improved. Regional coverage varied, reflecting the distribution of dermatologists, the ratio of public to private healthcare, and difficulties in recruiting certain clinics. This study highlights the importance of a nationwide registry when managing systemic pharmacotherapy of atopic dermatitis.
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| 14. |
- Anbalagan, Anbarasan, 1988-
(författare)
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A passage to wastewater nutrient recovery units : Microalgal-Bacterial bioreactors
- 2018
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Konstnärligt arbete (övrigt vetenskapligt/konstnärligt)abstract
- In recent years, the microalgal–bacterial process has been considered to be a very attractive engineering solution for wastewater treatment. However, it has not been widely studied in the context of conventional wastewater treatment design under Swedish conditions. The technology holds several advantages: as a CO2 sink, ability to withstand cold conditions, ability to grow under low light, fast settling without chemical precipitation, and reducing the loss of valuable nutrients (CO2, N2, N2O, PO4). The process also provides the option to be operated either as mainstream (treatment of municipal wastewater) or side stream (treatment of centrate from anaerobic digesters) to reduce the nutrient load of the wastewater. Furthermore, the application is not only limited to wastewater treatment; the biomass can be used to synthesise platform chemicals or biofuels and can be followed by recovery of ammonium and phosphate for use in agriculture.In the present study, the feasibility of applying the process in Swedish temperature and light conditions was investigated by implementing microalgae within the activated sludge process. In this context, the supporting operational and performance indicators (hydraulic retention time (HRT), sludge retention time (SRT) and nutrients removal) were evaluated to support naturally occurring consortia in photo-sequencing and continuous bioreactor configuration. Furthermore, CO2 uptake and light spectrum-mediated nutrient removal were investigated to reduce the impact on climate and the technical challenges associated with this type of system.The results identified effective retention times of 6 and 4 days (HRT = SRT) under limited lighting to reduce the electrical consumption. From the perspective of nitrogen removal, the process demands effective CO2 input either in the mainstream or side stream treatment. The incorporation of a vertical absorption column demonstrated effective CO2 mass transfer to support efficient nitrogen and phosphorus removal as a side stream treatment. However, the investigation of a continuous single-stage process as the mainstream showed a requirement for a lower SRT in comparison to semi-continuous operation due to faster settlability, regardless of inorganic carbon. Furthermore, the process showed an effective reduction of influent phosphorus and organic compounds (i.e. COD/TOC) load in the wastewater as a result of photosynthetic aeration. Most importantly, the operation was stable at the temperature equivalent of wastewater (12 and 13 ˚C), under different lighting (white, and red-blue wavelengths) and retention times (6 and 1.5 d HRT) with complete nitrification. Additionally, the biomass production was stable with faster settling properties without any physiochemical separation.The outcomes of this thesis on microalgal–bacterial nutrient removal demonstrates that (1) photosynthesis-based aeration at existing wastewater conditions under photo-sequential and continuous photobioreactor setup, (2) flocs with rapid settling characteristics at all studied retention times, (3) the possibility of increasing carbon supplementation to achieve higher carbon to nitrogen balance in the photobioreactor, and (4) most importantly, nitrification-based microalgal biomass uptake occurred at all spectral distributions, lower photosynthetic active radiation and existing wastewater conditions.
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| 15. |
- Anbalagan, Anbarasan, et al.
(författare)
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Continuous microalgae-activated sludge flocs for remediation of municipal wastewater under low temperature
- 2017
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Konferensbidrag (refereegranskat)abstract
- The operational performance of indigenous microalgae-activated sludge was evaluated regarding the nutrient removal efficiency using raw wastewater collected from Västerås wastewater treatment plant, Sweden at limited artificial surface lighting (290 μmol m-1 sec-1) and Nordic wastewater conditions (13°C). Additionally, the oxygen production and consumption, biomass concentration and its settling was evaluated during the symbiotic algal-bacterial interaction. The results confirmed oxygenic organic compound removal (COD removal of 65-94%) at higher (31-45 d) and lower (13-18 d) sludge retention time (SRT). Also, a complete removal of ammonium throughout the process and partial nitrite-nitrate removal at all SRTs (total nitrogen removal of 41- 62%) were observed. Likewise, a partial phosphorus (P)removal was observed in the effluent which provides an opportunity to capture free P fromthe effluent for recovery as fertiliser. Further, the microalgal growth was slower due to lightor inorganic carbon limitation or ammonium repression caused by higher internal recirculationas observed from ammonium and nitrite-nitrate levels in the PBR. Most importantly, effectivePBR biomass concentration based nutrient removal and relative sludge recirculation have tobe considered in the PBR design to avoid light limitation and activate symbiosis.
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| 16. |
- Anbalagan, Anbarasan, 1988-
(författare)
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Indigenous microalgae-activated sludge cultivation system for wastewater treatment
- 2016
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The municipal wastewater is mainly composed of water containing anthropogenic wastes that are rich in nutrients such as carbon, nitrogen and phosphorous. The cost for biological treatment of wastewater is increasing globally due to the population growth in urban cities. In general, the activated sludge (AS) process is a biological nutrient removal process used in wastewater treatment plants (WWTPs). The AS is composed of different microorganisms in which bacteria play a crucial role in wastewater treatment (WWT). During the process, air is bubbled to supply oxygen and methanol is added to improve nitrogen removal, which is released as a gas. Phosphorous is removed in the expense of precipitation chemicals. Altogether, the current process requires electrical energy, precipitation chemicals, handling of excess sludge and it emits carbon dioxide (CO2) as a by-product. This process is still in practise in the WWTPs since 1914 although numerous modifications are implemented to meet the stringent regulations in the European Union and globally.Microalgae are microorganisms that perform photosynthesis like plants. They are green and reproduce fast using available nutrients (nitrogen and phosphorous) and CO2 from their environment in the presence of light. As a result of photosynthesis, oxygen is released as waste gas. The synthesised oxygen during this process can be implemented to support the AS bacteria that leads to the microalgae activated sludge (MAAS) process. The main advantage is combined removal of nutrients.The vision of the research is to implement the indigenous microalgae cultivation in activated sludge process to consume CO2 and recover the nutrients from wastewater. This study is performed to improve the understanding of the process such as: light utilisation, nutrient removal and recovery of the biomass from wastewater in closed photo-bioreactors. Photo-bioreactors are vessels where the cultivation is carried out in the presence of light. At first, the influence of the light spectrum on micro-algal cultivation is investigated for photosynthetic growth. This is followed by operational challenges of the microalgae cultivation during the AS process. The process is experimentally performed in the photo-bioreactors with different treatment time of the raw wastewater. The results showed that 2 - 6 days of treatment time can be used for reducing nutrients in wastewater if the process is optimised further. Also, nutrient ratio is analysed for the availability of the micro-algal growth. Furthermore, the biogas potential of MAAS showed a biogas yield of about 60-80% within 5 to 9 days.At last, the experimental verification of chemically precipitated wastewater showed limitation of phosphorous for micro-algal growth. Additionally, the optimal oxygen supply through light response is verified for photo-bioreactors. The outcome of this study shows that knowing the right conditions can lower the treatment time. By doing so, a stable nutrient removal and reduction of precipitation chemicals can be established as well as a better recovery of valuable nutrients as phosphorous and nitrogen.
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| 17. |
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| 18. |
- Anbalagan, Anbarasan, et al.
(författare)
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Influence of hydraulic retention time on indigenous microalgae and activated sludge process
- 2016
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Ingår i: Water Research. - : Elsevier BV. - 0043-1354 .- 1879-2448. ; 91, s. 277-284
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Tidskriftsartikel (refereegranskat)abstract
- Integration of the microalgae and activated sludge (MAAS) process in municipal wastewater treatment and biogas production from recovered MAAS was investigated by studying the hydraulic retention time (HRT) of semi-continuous photo-bioreactors. An average total nitrogen (TN) removal efficiency (RE) of maximum 81.5 ± 5.1 and 64.6 ± 16.2% was achieved at 6 and 4 days HRT. RE of total phosphorous (TP) increased slightly at 6 days (80 ± 12%) HRT and stabilized at 4 days (56 ± 5%) and 2 days (55.5 ± 5.5%) HRT due to the fluctuations in COD and N/P mass ratio of the periodic wastewater. COD and organic carbon were removed efficiently and a rapidly settleable MAAS with a sludge volume index (SVI_10) of less than 117 mL g-1 was observed at all HRTs. The anaerobic digestion of the untreated MAAS showed a higher biogas yield of 349 ± 10 mL g VS-1 with 2 days HRT due to a low solids retention time (SRT). Thermal pretreatment of the MAAS (120 °C, 120 min) did not show any improvement with biogas production at 6 days (269 ± 3 (untreated) and 266 ± 16 (treated) mL gVS-1), 4 days (258 ± 11(untreated) and 263 ± 10 (treated) mL gVS-1) and 2 days (308 ± 19 mL (treated) gVS-1) HRT. Hence, the biogas potential tests showed that the untreated MAAS was a feasible substrate for biogas production. Results from this proof of concept support the application of MAAS in wastewater treatment for Swedish conditions to reduce aeration, precipitation chemicals and CO2 emissions.
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| 19. |
- Anbalagan, Anbarasan, et al.
(författare)
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Influence of iron precipitated condition and light intensity on microalgae activated sludge based wastewater remediation
- 2017
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Ingår i: Chemosphere. - : Elsevier. - 0045-6535 .- 1879-1298. ; , s. 1523-1530
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Tidskriftsartikel (refereegranskat)abstract
- The indigenous microalgae-activated sludge (MAAS) process during remediation of municipal wastewater was investigated by studying the influence of iron flocculation step and light intensity. In addition, availability of total phosphorous (P) and photosynthetic activity was examined in fed-batch and batch mode under northern climatic conditions and limited lighting. This was followed by a semi-continuous operation with 4 d of hydraulic retention time and mean cell residence time of 6.75 d in a photo-bioreactor (PBR) with varying P availability. The fed-batch condition showed that P concentrations of 3–4 mg L−1 were effective for photosynthetic chl. a development in iron flocculated conditions. In the PBR, the oxygen evolution rate increased with increase in the concentration of MAAS (from 258 to 573 mg TSS L−1) at higher surface photosynthetic active radiation (250 and 500 μmol m−2 s−1). Additionally, the rate approached a saturation phase at low MAAS (110 mg L−1) with higher light intensities. Semi-continuous operation with luxury P uptake and effective P condition showed stable average total nitrogen removal of 88 and 92% respectively, with residual concentrations of 3.77 and 2.21 mg L−1. The corresponding average P removal was 68 and 59% with residual concentrations of 2.32 and 1.75 mg L−1. The semi-continuous operation produced a rapidly settleable MAAS under iron flocculated condition with a settling velocity of 92–106 m h−1 and sludge volume index of 31–43 ml g−1 in the studied cases.
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| 20. |
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| 21. |
- Axelsson, Lena, et al.
(författare)
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Unmet Palliative Care Needs Among Patients With End-Stage Kidney Disease : A National Registry Study About the Last Week of Life
- 2018
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Ingår i: Journal of Pain and Symptom Management. - : Elsevier. - 0885-3924 .- 1873-6513. ; 55:2, s. 236-244
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Tidskriftsartikel (refereegranskat)abstract
- Context. End-stage kidney disease (ESKD) is characterized by high physical and psychological burden, and therefore, more knowledge about the palliative care provided close to death is needed. Objectives. To describe symptom prevalence, relief, and management during the last week of life, as well as end-of-life communication, in patients with ESKD. Methods. This study was based on data from the Swedish Register of Palliative Care. Patients aged 18 or older who died from a chronic kidney disease, with or without dialysis treatment (International Classification of Diseases, Tenth Revision, Sweden; N18.5 or N18.9), during 2011 and 2012 were selected. Results. About 472 patients were included. Of six predefined symptoms, pain was the most prevalent (69%), followed by respiratory secretion (46%), anxiety (41%), confusion (30%), shortness of breath (22%), and nausea (17%). Of patients with pain and/or anxiety, 32% and 44%, respectively, were only partly relieved or not relieved at all. Of patients with the other symptoms, a majority (55%-84%) were partly relieved or not relieved at all. End-of-life discussions were reported in 41% of patients and 71% of families. A minority died in specialized palliative care: 8% in hospice/inpatient palliative care and 5% in palliative home care. Of all patients, 19% died alone. Bereavement support was offered to 38% of families. Conclusion. Even if death is expected, most patients dying with ESKD had unmet palliative care needs regarding symptom management, advance care planning, and bereavement support. (C) 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.
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| 22. |
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| 23. |
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| 24. |
- Bargholtz, Chr., et al.
(författare)
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The WASA detector facility at CELSIUS
- 2008
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 594:3, s. 339-350
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Tidskriftsartikel (refereegranskat)abstract
- The WASA 4 pi multidetector system, aimed at investigating light meson production in light ion collisions and eta meson rare decays at the CELSIUS storage ring in Uppsala is presented. A unique feature of the system is the use of hydrogen pellets as internal targets for the first time. A detailed description of the design, together with the anticipated and achieved performance parameters are given. (C) 2008 Elsevier B.V. All rights reserved.
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| 25. |
- Bhutani, Naveen, et al.
(författare)
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Energy assessment of Paper Machines
- 2012
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Ingår i: Energy Procedia. - : Elsevier. - 1876-6102. ; 14, s. 955-963
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Tidskriftsartikel (refereegranskat)abstract
- There is a large value in making Pulp and Paper mills more energy efficient. ABB has developed an energy assessment service where opportunities to save energy in the paper machine are identified. The energy assessment is done by quantifying energy flows, benchmarking energy users, data mining and steam sensitivity analysis and by experiments and additional measurements at the paper machine. Energy quantification helped in identifying main energy consumer, benchmarking was useful to assess the gap between operating performance and best performance whereas data mining and steam sensitivity analysis helped in studying the impact of key operating variables on performance of paper machines. After the assessment an action plan was presented to the mill for energy efficiency improvement together with a return on investment.
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| 26. |
- Bizzarro, Fernando, et al.
(författare)
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Party Strength and Economic Growth
- 2015
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- While a large literature suggests an important role for political parties in economic development, this is the first attempt to lay out a comprehensive theory and a reasonably comprehensive empirical test of the proposition. We argue that strong parties broaden the constituencies to which policy makers respond and help politicians solve coordination problems. These features help ensure better economic management, public services, and political stability. And this, in turn, enhances economic growth. Drawing on a novel measure of party strength from the Varieties of Democracy dataset, we test this theory on data drawn from more than 150 countries, observed annually from 1900–2012. We identify a sizeable effect which is robust to various specifications, estimators, and samples. The effect operates in both democracies and autocracies and is fairly stable across regions and time periods. We also find provisional evidence in favor of causal mechanisms pertaining to public services and political stability.
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| 27. |
- Bizzarro, Fernando, et al.
(författare)
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Party Strength and Economic Growth
- 2018
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Ingår i: World Politics. - 0043-8871 .- 1086-3338. ; 70:2, s. 275-320
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Tidskriftsartikel (refereegranskat)abstract
- © Trustees of Princeton University 2018. While a large literature suggests an important role for political parties in development, this article is the first attempt to layout and test a comprehensive theory connecting parties to economic growth. The authors argue that strong parties broaden the constituencies to which policymakers respond and help politicians solve coordination problems. These features help to ensure better economic management, public services, and political stability. And this, in turn, enhances economic growth. Drawing on a novel measure of party strength from the Varieties of Democracy data set, the authors test this theory on data drawn from more than 150 countries observed annually from 1901-2010. They identify a sizeable effect that is robust to various specifications, estimators, and samples. The effect operates in both democracies and autocracies, and is fairly stable across regions and time periods.
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| 28. |
- Coppedge, Michael, et al.
(författare)
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The Methodology of “Varieties of Democracy” (V-Dem)
- 2019
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Ingår i: BMS Bulletin of Sociological Methodology/ Bulletin de Methodologie Sociologique. - : SAGE Publications. - 0759-1063 .- 2070-2779. ; 143, s. 107-133
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Tidskriftsartikel (refereegranskat)abstract
- This article describes and discusses the new generation of methodological responses to measuring democracy and related issues generated by Varieties of Democracy (V-Dem). V-Dem is distinct in several regards in addition to its unique level of disaggregation, by the combination of: historical data extending back to 1900 and for a large selection among them to 1789 for many countries in the world; use of multiple, independent coders for each evaluative question; inter-coder reliability tests incorporated into a custom designed Bayesian item-response theory measurement model; provision of confidence bounds for all point estimates associated with expert-coded questions as well as for all indices; multiple indices reflecting varying theories of democracy; fully transparent aggregation procedures; and that all data are made freely available, including original coder-level judgments (exclusive of any personal identifying information).
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| 29. |
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| 30. |
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| 31. |
- Dahlström, Carl, 1972, et al.
(författare)
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The QoG Expert Survey II Report
- 2015
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The Quality of Government Expert Survey II is second second wave of the global online survey of experts on bureaucratic structure and bureaucratic behavior. The questionnaire contained 71 substantive questions, including questions on how bureaucrats are hired, fired and promoted; extent of impartiality in bureaucratic decision-making, corruption and others. About 1,300 questionnaire were completed and experts answers aggregated at the country-level. 122 countries have expert input from three or more experts.
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| 32. |
- Duraj, Frans, et al.
(författare)
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Tarmtransplantation : Första svenska tunntarmstransplantationen till en vuxen patient med pseudoobstruktion
- 1998
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Ingår i: Läkartidningen. - 0023-7205 .- 1652-7518. ; 95:28-29, s. 3172-3176
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Tidskriftsartikel (refereegranskat)abstract
- Recent advances, first and foremost the development of new immunosuppressive agents, have markedly improved the outcome of intestinal transplantation, which is a treatment option for patients with serious intestinal diseases who have become dependent on total parenteral nutrition. The first small bowel transplantation in Sweden was performed at Huddinge Hospital in 1997, in the adult patient with intestinal pseudo-obstruction. The article reports the course of this patient and an update of international progress in intestinal transplantation.
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| 33. |
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| 34. |
- Ekström, Erik, 1977-, et al.
(författare)
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Auctions with an Invitation Cost
- 2021
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Ingår i: International Game Theory Review. - : World Scientific. - 0219-1989. ; 23:1
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Tidskriftsartikel (refereegranskat)abstract
- We consider an auction in which a seller invites potential buyers to a sealed-bid first-price auction, without disclosing to the buyers the number of extended invitations. In the presence of a fixed invitation cost for each invited bidder, the whole auction can be described as a game, where the set of players consists of all bidders together with the seller. In a setting with fully observable common values we show the existence of a Nash equilibrium in mixed strategies. In this equilibrium, the seller should invite precisely one or two potential buyers with certain probabilities, and each invited buyer should place a randomized bid according to a certain distribution.
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| 35. |
- Ekström, Erik, et al.
(författare)
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Optimal closing of a momentum trade
- 2013
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Ingår i: Journal of Applied Probability. - : Cambridge University Press (CUP). - 0021-9002 .- 1475-6072. ; 50:2, s. 374-387
-
Tidskriftsartikel (refereegranskat)abstract
- There is an extensive academic literature that documents that stocks which have performed well in the past often continue to perform well over some holding period-so-called momentum. We study the optimal timing for an asset sale for an agent with a long position in a momentum trade. The asset price is modelled as a geometric Brownian motion with a drift that initially exceeds the discount rate, but with the opposite relation after an unobservable and exponentially distributed time. The problem of optimal selling of the asset is then formulated as an optimal stopping problem under incomplete information. Based on the observations of the asset, the agent wants to detect the unobservable change point as accurately as possible. Using filtering techniques and stochastic analysis, we reduce the problem to a one-dimensional optimal stopping problem, which we solve explicitly. We also show that the optimal boundary at which the investor should liquidate the trade depends monotonically on the model parameters.
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| 36. |
- Ekström, Erik, et al.
(författare)
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Optimal liquidation of a call spread
- 2010
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Ingår i: Journal of Applied Probability. - 0021-9002 .- 1475-6072. ; 47:2, s. 586-593
-
Tidskriftsartikel (refereegranskat)abstract
- We study the optimal liquidation strategy for a call spread in the case when an investor, who does not hedge, believes in a volatility that differs from the implied volatility. The liquidation problem is formulated as an optimal stopping problem, which we solve explicitly. We also provide a sensitivity analysis with respect to the model parameters.
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| 37. |
- Ekström, Erik, et al.
(författare)
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Optimal liquidation of a pairs trade
- 2011
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Ingår i: Advanced Mathematical Methods in Finance. - : Springer-Verlag New York.
-
Bokkapitel (refereegranskat)
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| 38. |
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| 39. |
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| 40. |
- Ekström, Magnus, et al.
(författare)
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Exertional breathlessness related to medical conditions in middle-aged people: the population-based SCAPIS study of more than 25,000 men and women.
- 2024
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Ingår i: Respiratory research. - : BioMed Central (BMC). - 1465-993X .- 1465-9921. ; 25:1
-
Tidskriftsartikel (refereegranskat)abstract
- Breathlessness is common in the population and can be related to a range of medical conditions. We aimed to evaluate the burden of breathlessness related to different medical conditions in a middle-aged population.Cross-sectional analysis of the population-based Swedish CArdioPulmonary bioImage Study of adults aged 50-64years. Breathlessness (modified Medical Research Council [mMRC]≥2) was evaluated in relation to self-reported symptoms, stress, depression; physician-diagnosed conditions; measured body mass index (BMI), spirometry, venous haemoglobin concentration, coronary artery calcification and stenosis [computer tomography (CT) angiography], and pulmonary emphysema (high-resolution CT). For each condition, the prevalence and breathlessness population attributable fraction (PAF) were calculated, overall and by sex, smoking history, and presence/absence of self-reported cardiorespiratory disease.We included 25,948 people aged 57.5±[SD] 4.4; 51% women; 37% former and 12% current smokers; 43% overweight (BMI 25.0-29.9), 21% obese (BMI≥30); 25% with respiratory disease, 14% depression, 9% cardiac disease, and 3% anemia. Breathlessness was present in 3.7%. Medical conditions most strongly related to the breathlessness prevalence were (PAF 95%CI): overweight and obesity (59.6-66.0%), stress (31.6-76.8%), respiratory disease (20.1-37.1%), depression (17.1-26.6%), cardiac disease (6.3-12.7%), anemia (0.8-3.3%), and peripheral arterial disease (0.3-0.8%). Stress was the main factor in women and current smokers.Breathlessness mainly relates to overweight/obesity and stress and to a lesser extent to comorbidities like respiratory, depressive, and cardiac disorders among middle-aged people in a high-income setting-supporting the importance of lifestyle interventions to reduce the burden of breathlessness in the population.
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| 41. |
- Ekström, Magnus Pär, et al.
(författare)
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The association of body mass index, weight gain and central obesity with activity-related breathlessness : the Swedish Cardiopulmonary Bioimage Study
- 2019
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Ingår i: Thorax. - : BMJ Publishing Group Ltd. - 0040-6376 .- 1468-3296. ; 74:10, s. 958-964
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: Breathlessness is common in the population, especially in women and associated with adverse health outcomes. Obesity (body mass index (BMI) >30 kg/m(2)) is rapidly increasing globally and its impact on breathlessness is unclear.Methods: This population-based study aimed primarily to evaluate the association of current BMI and self-reported change in BMI since age 20 with breathlessness (modified Research Council score >= 1) in the middle-aged population. Secondary aims were to evaluate factors that contribute to breathlessness in obesity, including the interaction with spirometric lung volume and sex.Results: We included 13 437 individuals; mean age 57.5 years; 52.5% women; mean BMI 26.8 (SD 4.3); mean BMI increase since age 20 was 5.0 kg/m(2); and 1283 (9.6%) reported breathlessness. Obesity was strongly associated with increased breathlessness, OR 3.54 (95% CI, 3.03 to 4.13) independent of age, sex, smoking, airflow obstruction, exercise level and the presence of comorbidities. The association between BMI and breathlessness was modified by lung volume; the increase in breathlessness prevalence with higher BMI was steeper for individuals with lower forced vital capacity (FVC). The higher breathlessness prevalence in obese women than men (27.4% vs 12.5%; p<0.001) was related to their lower FVC. Irrespective of current BMI and confounders, individuals who had increased in BMI since age 20 had more breathlessness.Conclusion: Breathlessness is independently associated with obesity and with weight gain in adult life, and the association is stronger for individuals with lower lung volumes.
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| 42. |
- Engström, Gunnar, et al.
(författare)
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Pulmonary function and atherosclerosis in the general population : causal associations and clinical implications
- 2024
-
Ingår i: European Journal of Epidemiology. - : Springer Nature. - 0393-2990 .- 1573-7284. ; 39:1, s. 35-49
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Tidskriftsartikel (refereegranskat)abstract
- Reduced lung function is associated with cardiovascular mortality, but the relationships with atherosclerosis are unclear. The population-based Swedish CArdioPulmonary BioImage study measured lung function, emphysema, coronary CT angiography, coronary calcium, carotid plaques and ankle-brachial index in 29,593 men and women aged 50–64 years. The results were confirmed using 2-sample Mendelian randomization. Lower lung function and emphysema were associated with more atherosclerosis, but these relationships were attenuated after adjustment for cardiovascular risk factors. Lung function was not associated with coronary atherosclerosis in 14,524 never-smokers. No potentially causal effect of lung function on atherosclerosis, or vice versa, was found in the 2-sample Mendelian randomization analysis. Here we show that reduced lung function and atherosclerosis are correlated in the population, but probably not causally related. Assessing lung function in addition to conventional cardiovascular risk factors to gauge risk of subclinical atherosclerosis is probably not meaningful, but low lung function found by chance should alert for atherosclerosis.
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| 43. |
- Greiff, Lennart, et al.
(författare)
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Challenge-induced plasma exudation and mucinous secretion in human airways
- 2005
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Ingår i: Clinical Physiology and Functional Imaging. - 1475-0961. ; 25:4, s. 241-245
-
Tidskriftsartikel (refereegranskat)abstract
- Secretion of mucins and exudation of plasma are distinct processes of importance to innate immunity and inflammatory disease. Yet, little is known about their relation in human airways. The objective of the present study was to use the human nasal airway to determine mucinous secretion and plasma exudation in response to common challenge agents and mediators. Ten healthy volunteers were subjected to nasal challenge-lavage procedures. Thus, the nasal mucosa was exposed to increasing doses of histamine (40 and 400 microg ml(-1)), methacholine (12.5 and 25 mg) and capsaicin (30 and 300 ng ml(-1)). Fucose was selected as a global marker of mucinous secretion and alpha(2)-macroglobulin as an index of exudation of bulk plasma. All challenge agents increased the mucosal output of fucose to about the same level (P<0.01-0.05). Once significant secretion had been induced the subsequently increased dose of the challenge agent, in the case of histamine and methacholine, failed to further increase the response. Only histamine increased the mucosal output of alpha(2)-macroglobulin (P<0.01). We conclude that prompt but potentially rapidly depleted mucinous secretion is common to different kinds of airway challenges, whereas inflammatory histamine-type mediators are required to produce plasma exudation. Along with the acknowledged secretion of mucins, a practically non-depletable, pluripotent mucosal output of plasma emerges as an important component of the innate immunity of human airways.
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| 44. |
- Gånemo, Agneta, et al.
(författare)
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Quality of life in Swedish children with eczema
- 2007
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Ingår i: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 1651-2057 .- 0001-5555. ; 87:4, s. 345-349
-
Tidskriftsartikel (refereegranskat)abstract
- The burdens of childhood eczema are many and some can be assessed with quality of life (QoL) questionnaires. Seventy-eight Swedish children with mild-to-severe eczema ("atopic dermatitis", prurigo Besnier), fulfilling established diagnostic criteria, were investigated for the effect of eczema on QoL. This was measured with validated questionnaires: the Infants' Dermatitis Quality of Life Index (IDQOL), the Children's Dermatology Life Quality Index (CDLQI), and the Dermatitis Family Impact Questionnaire (DFI). The study also included scoring of eczema severity. The median score was 7.0 (range 1-18) for IDQOL, 6.0 (range 2-18) for the CDLQI, and 8.0 (range 0-27) for DFI. There was no significant difference in scores between boys and girls. The DFI scores were higher for younger than for older children, and also higher for those with both eczema and asthma, food allergy/intolerance, allergic rhinoconjunctivitis or urticaria. The QoL scores correlated significantly with the Rajka & Langeland score, but not with objective SCORAD. The outcome of the QoL instruments in this study clearly demonstrates that childhood eczema affects the children's and their families' QoL. QoL data offers a patient-oriented outcome measure of importance for understanding the patients' and their families' situation. Such information can also be used in intervention studies and in the allocation of healthcare resources to eczema care.
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| 45. |
- Hamrin, Kjell, et al.
(författare)
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Structure studies of sulphur compounds by ESCA
- 1968
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Ingår i: Chemical Physics Letters. - 0009-2614 .- 1873-4448. ; 1:11, s. 557-559
-
Tidskriftsartikel (refereegranskat)abstract
- Results, obtained by means of the ESCA-technique (Electron Spectroscopy for Chemical Analysis), are reported on the correlation between the binding energy of the inner electrons of sulphur and the chemical state and environment, with particular emphasis on the sulphur-oxygen bond. A charge-binding energy correlation is established which can be used for the estimation of charge on sulphur in compounds with uncertain structure or composition.
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| 46. |
- Hermansson, K., et al.
(författare)
-
An Automated Approach to Building and Simulating Dynamic District Heating Networks
- 2018
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Ingår i: IFAC-PapersOnLine. - : Elsevier B.V.. - 2405-8963. ; 51:2, s. 855-860
-
Tidskriftsartikel (refereegranskat)abstract
- In Nordic countries, district heating accounts for a large share of the consumers’ heat demand. In Sweden, roughly 50% of the total heat demand is attributed to district heating. Which, over the past few years, is equivalent to around 50 TWh, and imposes a difficult balance between supply and demand for the suppliers of district heating. For large networks the propagation of heat from supplier to end-user can vary several hours. Further complexities of large networks, which can consist of multiple overlapping rings, is that during transient conditions the flow can actually change direction. A dynamic modeling library has been developed in Modelica using OpenModelica for district heating networks. Methods for modeling, handling data, simulating and the visualization of results has been developed using Matlab. The model has been validated using data from Mälarenergi AB, a local provider of district heating in Västerås, Sweden. The model provides to an acceptable degree in predicting the heat propagation and temperature distribution in a localized case study. Adding a higher level of robustness, the model has the capacity to handle bi-directional and reversing flows in complex ring structures. Through this work, the combination of OpenModelica and Matlab, a framework for automating the building and simulation of district heating networks is obtainable. The implications of automating network modeling from computer-aided design drawings allows for a quick robust overview of how the network is working and how prospective additions to the network could impact the end-users. Furthermore, incorporating visual aspects for heat propagation in a network contributes to a higher understanding of complex network structures.
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| 47. |
- Hjalmarsson, Johannes, et al.
(författare)
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Enhancing the value of large-scale energy storage systems in congested distribution grids using service stacking
- 2023
-
Ingår i: Journal of Energy Storage. - 2352-152X .- 2352-1538.
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Energy storage systems (ESS) are suitable for many grid applications, where some have large seasonal variations. By combining additional services, i.e., service stacking, companies with energy storage assets may generate additional revenue as well as provide services to the power system. This paper aims to highlight and estimate the technical and economic potential of stacking services using energy storage systems in congested a distribution grid. A scheduling optimization tool was implemented for a large-scale battery ESS providing a selection of deemed relevant services over two years. The results show that there is a great potential to enhance the value of the ESS significantly depending on the service portfolio layout. A capacity life loss model was also implemented to analyse the degradation of the ESS, and the cycle aging was estimated for the chosen portfolios. The results showed that a fully stacked portfolio does not necessarily result in increased cycle aging, but that it depended on the services in the portfolio. The cycle aging was affected the most by stacking flexibility with energy arbitrage, while frequency regulation services only resulted in a few additional cycles during each year of operation.
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| 48. |
- Jensen, Carl, et al.
(författare)
-
Hinder och möjligheter för att öka källsortering av plastavfall från tillverkningsindustrin
- 2020
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The consumption of plastics and the management of the generated amounts of plastic waste are two issues that have been some of the most prominent in the environmental debate in recent years. Today, large quantities of plastic waste from the Swedish manufacturing industry is generated that are not sorted for recycling but end up in combustible residual waste going to energy recovery, which means a significant waste of resources. Although large quantities of plastic waste originate from the manufacturing industry, the vast majority of initiatives related to a more resource-efficient management of plastic waste have focused on the plastic waste generated related to consumption. Relatively little focus has been on the primary plastic waste generated from the manufacturing industry. The purpose of this project has been to contribute to increase the source sorting and recycling of plastic waste from the Swedish manufacturing industry. The goals were to identify and evaluate significant barriers faced by the Swedish manufacturing industry to increase the sorting of plastic in Sweden and to propose how the sorting of the plastic waste can increase. The project and its results were based on a survey answered by manufacturing companies, which was supplemented by interviews with waste and recycling actors.
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| 49. |
- Johansson, Carl, et al.
(författare)
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Culturally sensitive active ageing seen through the lens of the welfare theory of health : assistant nurses’ views
- 2023
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Ingår i: Frontiers in Psychology. - : Frontiers Media SA. - 1664-1078. ; 14
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Tidskriftsartikel (refereegranskat)abstract
- Assistant nurses caring for older adults with immigrant backgrounds are on the front lines of a practical, theoretical, and policy battlefield. They need to implement culturally sensitive care provision while not overstating the importance of culture, thereby, contributing to a negative picture of older immigrants as especially problematic. One proposed way to strike such a balance is the welfare theory of health (WTH). In this article, we let assistant nurses apply the WTH to a series of questions in four different vignettes representing the life stories of older persons who characterize typical dilemmas described by the theory. The results show that, through the lens of the WTH, assistant nurses looked for individual care preferences rather than stereotypical ideas about cultural characteristics. Further, the assistant nurses expressed a desire to get to know the persons more deeply to better interpret and understand their individual preferences. Thus, the theoretical framework is useful not only for exposing vulnerabilities to which some older adults with immigrant backgrounds may be exposed, but also for finding ways to mitigate the vulnerability by illuminating vital life goals and using them as a framework to organize care. This approach allows for mitigating the gap between the vital life goals and available resources to achieve a holistic state of health.
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| 50. |
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