| 1. |
|
|
| 2. |
|
|
| 3. |
- Bourdieu, Pierre, et al.
(author)
-
Leve idrottspedagogiken : En vänbok tillägnad Lars-Magnus Engström
- 2005
-
Book (other academic/artistic)abstract
- Vem ägnar sig åt idrott? Vilken betydelse har fritiden i barns och ungdomars liv? Vad innebär hälsa i skolämnet idrott och hälsa?Leve idrottspedagogiken! tillägnas Lars-Magnus Engström. Texterna i boken speglar delar av det idrottspedagogiska forskningsområdet i Sverige, vars framväxt Lars-Magnus Engström varit den främste företrädaren för. Läsaren får här ta del av exempelvis idrottskulturen, fritidskulturen och skolans ämne idrott och hälsa. Genomgående handlar texterna om villkoren för barns och ungdomars deltagane och om de olika lärprocesser som sker i anslutning till idrottsutövning.Lars-Magnus Engström har gjort betydande insatser som forskare och lärare samt som professor vid Lärarhögskolan i Stockholm och vid Gymnastik- och idrottshögskolan. I snart fyrtion år har han arbetat med studier kring påverkans- och lärprocesser i idrott. Hans forskning har främst kretsat kring människors idrottsvanor och vilka som utvecklar en fysiskt aktiv livsstil. Idrotts- och motionsutövningar ger både ett så kallat egenvärde och investeringsvärde. Med dessa begrepp bland många andra har Lars-Magnus Engström bidragit till en fördjupad vetenskaplig förståelse av idrottskulturen.De flesta författarna har eller har haft Lars-Magnus Engström som handledare och tillhör forskningsgruppen för pedagogik, idrott och fritidskultur. Redaktörer för boken är Karin Redelius och Håkan Larsson.
|
|
| 4. |
|
|
| 5. |
- Hammond, Maria, et al.
(author)
-
Sensitive detection of aggregated prion protein via proximity ligation
- 2014
-
In: Prion. - : Informa UK Limited. - 1933-6896 .- 1933-690X. ; 8:3, s. 261-265
-
Journal article (peer-reviewed)abstract
- The DNA assisted solid-phase proximity ligation assay (SP-PLA) provides a unique opportunity to specifically detect prion protein (PrP) aggregates by investigating the collocation of three or more copies of the specific protein. We have developed a SP-PLA that can detect PrP aggregates in brain homogenates from infected hamsters even after a 10(7)-fold dilution. In contrast, brain homogenate from uninfected animals did not generate a detectable signal at hundred-fold higher concentration. Using either of the two monoclonal anti-PrP antibodies 3F4 and 6H4 we successfully detected low concentrations of aggregated PrP. The presented results provide a proof of concept that this method might be an interesting tool in the development of diagnostic approaches of prion diseases.
|
|
| 6. |
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
|
|
| 10. |
|
|
| 11. |
|
|
| 12. |
- Shih, Tommy, et al.
(author)
-
State actors’ mobilisation of resources for innovation : a case study of a Chinese vaccine
- 2016
-
In: The IMP Journal. - 2059-1403 .- 0809-7259. ; 10:2, s. 296-316
-
Journal article (peer-reviewed)abstract
- Purpose - The purpose of this paper is to explore how state actors mobilise resources in business networks to facilitate innovation. Design/methodology/approach - A single case study method is used. The case from the Chinese biotechnology sector illustrates how state actors mobilise resources in a network context in order to develop, produce and use a vaccine. Findings - The case findings demonstrate that state actors indirectly, as well as actively, are involved in the whole innovation process by mobilising resources necessary for the development, production and use of the vaccine. State actors influence other actors, both political and business, and provide resources in order to facilitate innovation. Practical implications - The paper illustrates that state actors, in the specific case, play an important and active role throughout the whole innovation process. This opens up the issue of the possible extended role of state actors in innovation. Originality/value - Over the past decades, Chinese state actors have played an active role in the business landscape. This paper explores state actors' influence on the innovation process on the network level.
|
|
| 13. |
|
|
| 14. |
- Waluszewski, Alexandra, et al.
(author)
-
Resource interfaces telling other stories about the commercial use of new technology : The embedding of biotech solutions in US, China and Taiwan
- 2009
-
In: The IMP Journal. - Oslo : The IMP Group. - 2059-1403 .- 0809-7259. ; 3:2, s. 86-123
-
Journal article (peer-reviewed)abstract
- This study focuses on the embedding of new biotech solutions into three business landscapes - US, China and Taiwan. A "state-of-the-art" chromatography system tuned for operating in the step between laboratory and large-scale production is used as the common point of departure to investigate the supplier-user interfaces involving biotechnology in each of the three countries; the resource interaction in the networks around each machine is mapped. The analysis identifies the influences left on these resource interfaces by the national frameworks of science, policy and business. The results stress the importance of established resource structures to enable use of new technical solutions, the facilitating and restricting role of local path dependency, and the problems faced by policy in breeding network-level interactions sustaining the development and use of biotech solutions.
|
|
| 15. |
|
|
| 16. |
|
|
| 17. |
|
|
| 18. |
- Wik, Lotta, et al.
(author)
-
Separate mechanisms act concurrently to shed and release the prion protein from the cell
- 2012
-
In: Prion. - : Informa UK Limited. - 1933-6896 .- 1933-690X. ; 6
-
Journal article (peer-reviewed)abstract
- The cellular prion protein (PrPC) is attached to the cell membrane via its glycosylphosphatidylinositol (GPI)-anchor and is constitutively shed into the extracellular space. Here, three different mechanisms are presented that concurrently shed PrPC from the cell. The fast alpha-cleavage released a N-terminal fragment (N1) into the medium and the extreme C-terminal cleavage shed soluble full-length (FL-S) PrP and C-terminally cleaved (C1-S) fragments outside the cell. Also, a slow exosomal release of full-length (FL) and C1-fragment (C1) was demonstrated. The three separate mechanisms acting simultaneously, but with different kinetics, have to be taken into consideration when elucidating functional roles of PrPC and also when processing of PrPC is considered as a target for intervention in prion diseases. Further, in this study it was shown that metalloprotease inhibitors affected the extreme C-terminal cleavage and shedding of PrPC. The metalloprotease inhibitors did not influence the alpha-cleavage or the exosomal release. Taken together, these results are important for understanding the different mechanisms acting in parallel in the shedding and cleavage of PrPC.
|
|
| 19. |
- Wik, Lotta, et al.
(author)
-
Älvsborgssjukan hos älg - nya rön
- 2013
-
In: Svensk Veterinärtidning. - 0346-2250. ; 65, s. 17-20
-
Journal article (other academic/artistic)abstract
- Älvsborgssjukan hos älg rönte stor uppmärksamhet under 1980- och 90-talen, men fortfarande finns inga definitiva svar på frågan om den underliggande orsaken. En av teorierna är att symtomen beror på prionsjukdom hos älgarna. Författarna har jämfört priongenen PRNP hos skandinaviska hjortdjur med motsvarande gen hos nordamerikanska hjortdjur som drabbats av Chronic Wasting Disease, en ut - bredd och smittsam prionsjukdom.
|
|
