| 1. |
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| 2. |
- Kristanl, Matej, et al.
(författare)
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The Seventh Visual Object Tracking VOT2019 Challenge Results
- 2019
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Ingår i: 2019 IEEE/CVF INTERNATIONAL CONFERENCE ON COMPUTER VISION WORKSHOPS (ICCVW). - : IEEE COMPUTER SOC. - 9781728150239 ; , s. 2206-2241
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Konferensbidrag (refereegranskat)abstract
- The Visual Object Tracking challenge VOT2019 is the seventh annual tracker benchmarking activity organized by the VOT initiative. Results of 81 trackers are presented; many are state-of-the-art trackers published at major computer vision conferences or in journals in the recent years. The evaluation included the standard VOT and other popular methodologies for short-term tracking analysis as well as the standard VOT methodology for long-term tracking analysis. The VOT2019 challenge was composed of five challenges focusing on different tracking domains: (i) VOT-ST2019 challenge focused on short-term tracking in RGB, (ii) VOT-RT2019 challenge focused on "real-time" short-term tracking in RGB, (iii) VOT-LT2019 focused on long-term tracking namely coping with target disappearance and reappearance. Two new challenges have been introduced: (iv) VOT-RGBT2019 challenge focused on short-term tracking in RGB and thermal imagery and (v) VOT-RGBD2019 challenge focused on long-term tracking in RGB and depth imagery. The VOT-ST2019, VOT-RT2019 and VOT-LT2019 datasets were refreshed while new datasets were introduced for VOT-RGBT2019 and VOT-RGBD2019. The VOT toolkit has been updated to support both standard short-term, long-term tracking and tracking with multi-channel imagery. Performance of the tested trackers typically by far exceeds standard baselines. The source code for most of the trackers is publicly available from the VOT page. The dataset, the evaluation kit and the results are publicly available at the challenge website(1).
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| 3. |
- Chen, Hongxia, et al.
(författare)
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PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation
- 2024
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Ingår i: Molecular Cancer Research. - 1541-7786. ; 22:1, s. 94-103
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Tidskriftsartikel (refereegranskat)abstract
- Receptor tyrosine kinase KIT is frequently activated in acute myeloid leukemia (AML). While high PRL2 (PTP4A2) expression is correlated with activation of SCF/KIT signaling in AML, the underlying mechanisms are not fully understood. We discovered that inhibition of PRL2 significantly reduces the burden of oncogenic KIT-driven leukemia and extends leukemic mice survival. PRL2 enhances oncogenic KIT signaling in leukemia cells, promoting their proliferation and survival. We found that PRL2 dephosphorylates CBL at tyrosine 371 and inhibits its activity toward KIT, leading to decreased KIT ubiquitination and enhanced AKT and ERK signaling in leukemia cells.
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| 4. |
- Yang, Fangkai, et al.
(författare)
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Diffusion-Based Time Series Data Imputation for Cloud Failure Prediction at Microsoft 365
- 2023
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Ingår i: ESEC/FSE 2023 - Proceedings of the 31st ACM Joint Meeting European Software Engineering Conference and Symposium on the Foundations of Software Engineering. - : Association for Computing Machinery (ACM). ; , s. 2050-2055
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Konferensbidrag (refereegranskat)abstract
- Ensuring reliability in large-scale cloud systems like Microsoft 365 is crucial. Cloud failures, such as disk and node failure, threaten service reliability, causing service interruptions and financial loss. Existing works focus on failure prediction and proactively taking action before failures happen. However, they suffer from poor data quality, like data missing in model training and prediction, which limits performance. In this paper, we focus on enhancing data quality through data imputation by the proposed Diffusion+, a sample-efficient diffusion model, to impute the missing data efficiently conditioned on the observed data. Experiments with industrial datasets and application practice show that our model contributes to improving the performance of downstream failure prediction.
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| 5. |
- Bian, Wenjie, et al.
(författare)
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Diffusion behavior of Se(IV) and Re(VII) in biotite: effects of dry density and ionic strength
- 2023
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Ingår i: Journal of Radioanalytical and Nuclear Chemistry. - : Springer Nature. - 0236-5731 .- 1588-2780. ; 332:11, s. 4413-4425
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Tidskriftsartikel (refereegranskat)abstract
- Biotite is an important adsorption carrier in the constituent minerals of Beishan granite. In this work, the effects of compaction density and ionic strength on the diffusion behavior of Se(IV) and Re(VII) in biotite were studied by capillary in-diffusion method and diffusion cell through-diffusion method. When the compaction density decreases or the ionic strength increases, the apparent diffusion coefficient increases, and its values range between 10–11 and 10–9 m2/s. The relationship between De and εacc, ionic strength and εacc was fitted using Archie's law and compared with the parameters of other researchers.
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| 6. |
- Hu, Jinhong, et al.
(författare)
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Safety and immunogenicity of a malaria vaccine, Plasmodium falciparum AMA-1/MSP-1 chimeric protein formulated in montanide ISA 720 in healthy adults
- 2008
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Ingår i: PLOS ONE. - : PLOS. - 1932-6203. ; 3:4
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The P. falciparum chimeric protein 2.9 (PfCP-2.9) consisting of the sequences of MSP1-19 and AMA-1 (III) is a malaria vaccine candidate that was found to induce inhibitory antibodies in rabbits and monkeys. This was a phase I randomized, single-blind, placebo-controlled, dose-escalation study to evaluate the safety and immunogenicity of the PfCP-2.9 formulated with a novel adjuvant Montanide ISA720. Fifty-two subjects were randomly assigned to 4 dose groups of 10 participants, each receiving the test vaccine of 20, 50, 100, or 200 microg respectively, and 1 placebo group of 12 participants receiving the adjuvant only.METHODS AND FINDINGS: The vaccine formulation was shown to be safe and well-tolerated, and none of the participants withdrew. The total incidence of local adverse events (AEs) was 75%, distributed among 58% of the placebo group and 80% of those vaccinated. Among the vaccinated, 65% had events that were mild and 15% experienced moderate AEs. Almost all systemic adverse reactions observed in this study were graded as mild and required no therapy. The participants receiving the test vaccine developed detectable antibody responses which were boosted by the repeated vaccinations. Sixty percent of the vaccinated participants had high ELISA titers (>1:10,000) of antigen-specific antibodies which could also recognize native parasite proteins in an immunofluorescence assay (IFA).CONCLUSION: This study is the first clinical trial for this candidate and builds on previous investigations supporting PfCP-2.9/ISA720 as a promising blood-stage malaria vaccine. Results demonstrate safety, tolerability (particularly at the lower doses tested) and immunogenicity of the formulation. Further clinical development is ongoing to explore optimizing the dose and schedule of the formulation to decrease reactogenicity without compromising immunogenicity.TRIAL REGISTRATION: Chinese State Food and Drug Administration (SFDA) 2002SL0046; Controlled-Trials.com ISRCTN66850051 [66850051].
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| 7. |
- Li, Wenjie, et al.
(författare)
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La0.75Sr0.25Cr0.5Mn0.5O3-δ-Ce0.8Sm0.2O1.9 as composite electrodes in symmetric solid electrolyte cells for electrochemical removal of nitric oxide
- 2020
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Ingår i: Applied Catalysis B: Environmental. - : Elsevier BV. - 0926-3373. ; 264
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Tidskriftsartikel (refereegranskat)abstract
- Symmetric solid electrolyte cells with La0.75Sr0.25Cr0.5Mn0.5O3-δ (LSCM)-Ce0.8Sm0.2O1.9 (SDC) composite electrodes are employed for nitric oxide (NO) removal. The LSCM powders are synthesized and the cells with LSCM-SDC composite electrodes are fabricated successfully. The results show that moderate SDC addition in LSCM electrode improves the cell performance due to the expansion of three phase boundaries (TPBs). The electrode with 30 wt% SDC has the highest NO conversion of 69.2% and the lowest polarization resistance at 750 °C in 1000 ppm NO. The cathodic polarization activates the cathode because of the Cr/Mn ions reduction, more surface oxygen vacancies and Cr metal exsolution. The cell has good tolerances for H2O, CO2, and SO2, but excess O2 competes with NO for TPBs seriously. The sufficient stability and flexible operation mode of the cell are also proved. Finally, the NO adsorption mechanism on LSCM surface is revealed by density functional theory (DFT) calculations.
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| 8. |
- Li, Zhiyang, et al.
(författare)
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Magnetic carbon nanotube modified S-scheme TiO2-x/g-C3N4/CNFe heterojunction coupled with peroxymonosulfate for effective visible-light-driven photodegradation via enhanced interfacial charge separation
- 2023
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Ingår i: Separation and Purification Technology. - : Elsevier. - 1383-5866 .- 1873-3794. ; 308
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Tidskriftsartikel (refereegranskat)abstract
- To remediate water bodies contaminated with organic micropollutants, recyclable and visible-light-driven coupled photocatalysis-peroxymonosulfate (PMS) activation systems were established by synthesizing magnetic-carbon-nanotubes (CNFe) modified TiO2-x/g-C3N4/CNFe (TCNCNFe) S-scheme heterojunction with oxygen vacancies (O-v) by a simple hydrothermal-calcination approach. The introduction of O-v and CNFe enhances the visible-light-harvesting efficiency and the internal electric field across the heterojunction accompanying favorable energy band bending could effectively migrate the photoexcited electrons along the S-scheme mechanism, thus highly suppressing in situ recombination and improving charge separation. Therefore the TCNCNFe-(30-500)/PMS/Vis system achieved 95.4% removal efficiency of atrazine after 30 min irradiation, meanwhile exhibited excellent recyclability without metal ion leaching due to the unique pod-like nanostructure of CNFe. Moreover, the impacts of certain various reaction variables on pollutant removal were explored to evaluate the practical application potential. Interestingly, the biotoxicity of the treated reaction filtrate was significantly alleviated compared to that of ATZ solution. Furthermore, the exploration of photocatalytic reaction mechanism revealed that the dominant reactive oxidizing species contributed in the following order: h(+) > (OH)-O-center dot > O-center dot(2)- > (SO4-)-S-center dot, and the feasible photodegradation pathway of atrazine was presented based on the determined in-termediates. Hence, this research work holds great promise in ecological environment protection using sustainable solar energy.
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| 9. |
- Liu, Wenjie
(författare)
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2022 IEEE Wireless Communications and Networking Conference (WCNC)
- 2022
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Ingår i: 2022 IEEE Wireless Communications and Networking Conference (WCNC). - : IEEE. ; , s. 2136-2141
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Konferensbidrag (refereegranskat)abstract
- This paper studies the problem of predicting the spectrum efficiency (SE) for massive multiple-input multiple-output (MIMO) empowered 5G networks based on the reference signal received power (RSRP) collected from the drive test (DT). This problem is challenging because there is no precise model between the RSRP and the SE. The SE not only depends on the RSRP, which only captures the statistic of the channel, but also the beamforming strategy of the serving base station (BS) and the interference from the neighboring cells, which are not measured at the 5G client. This paper adopts a model-assisted data-driven approach to develop a machine learning model for the SE prediction. Specifically, a joint interference and SE prediction network is built, demonstrating prediction improvement over pure data-driven neural networks. In addition, a classification-assisted SE prediction network is constructed, which substantially reduces the prediction error at the low SE regime with marginally compromising the total prediction error. It is found that the model-assisted approach generally enhances the SE prediction accuracy by 2% approximately over a purely data-driven approach.
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| 10. |
- Liu, Wenjie, et al.
(författare)
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Probabilistic Detection of GNSS Spoofing using Opportunistic Information
- 2023
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Ingår i: Proceedings IEEE/ION Position, Location and Navigation Symposium, PLANS 2023. - : Institute of Electrical and Electronics Engineers (IEEE).
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Konferensbidrag (refereegranskat)abstract
- Global Navigation Satellite Systems (GNSS) are integrated into many devices. However, civilian GNSS signals are usually not cryptographically protected. This makes attacks that forge signals relatively easy. Considering modern devices often have network connections and on-board sensors, the proposed here Probabilistic Detection of GNSS Spoofing (PDS) scheme is based on such opportunistic information. PDS has at its core two parts. First, a regression problem with motion model constraints, which equalizes the noise of all locations considering the motion model of the device. Second, a Gaussian process, that analyzes statistical properties of location data to construct uncertainty. Then, a likelihood function, that fuses the two parts, as a basis for a Neyman-Pearson lemma (NPL)-based detection strategy. Our experimental evaluation shows a performance gain over the state-of-the-art, in terms of attack detection effectiveness.
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| 11. |
- Liu, Wenjie, et al.
(författare)
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UAV-Aided Radio Map Construction Exploiting Environment Semantics
- 2023
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Ingår i: IEEE Transactions on Wireless Communications. - : Institute of Electrical and Electronics Engineers (IEEE). - 1536-1276 .- 1558-2248. ; 22:9, s. 6341-6355
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Tidskriftsartikel (refereegranskat)abstract
- This paper constructs a full dimensional (6D) radio map to predict the channel gain between any transmitter location and any receiver location based on received signal strength (RSS) measurements between low-altitude aerial nodes and ground nodes. The main challenge is how to describe the signal strength attenuation due to the blockage from the environment. Conventional interpolation-type approaches fail to exploit the close relation between the radio map and the geometry of the environment. This paper proposes to construct radio maps by first estimating and constructing a multi-class 3D virtual obstacle map that describes the geometry of the environment with radio semantics. Mathematically, a least-squares problem is formulated to jointly estimate the virtual obstacle map and the propagation parameters. This problem is found to have a partial quasiconvexity that leads to the development of an efficient parameter estimation and radio map construction algorithm. Numerical experiments confirm that the proposed method substantially reduces the amount of measurement required for achieving the same radio map accuracy. It is also demonstrated that in a unmanned aerial vehicle (UAV)-aided relay communication scenario, a radio map assisted approach for UAV placement can achieve more than 50% capacity gain.
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| 12. |
- Luo, Xuhao, et al.
(författare)
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Intrinsic polarization-sensitive organic photodetector with self-assembled all-polymer heterojunction
- 2022
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Ingår i: Applied Physics Letters. - : AIP Publishing. - 0003-6951 .- 1077-3118. ; 121:23
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Tidskriftsartikel (refereegranskat)abstract
- Intrinsic polarization-sensitive photodetectors (IPPDs) have attracted considerable attention in recent years due to their simplicity in configuration, making them ideal candidates for compact and integrated polarization-sensitive sensing and imaging systems. Photoactive films with intrinsic optical anisotropy are necessary for IPPDs. This study reports an achievement of photoactive films based on all-polymer heterojunction films with in-plane optical anisotropy using a simple bottom-up self-assembly method. Both the donor (TQ1) and acceptor (N2200) polymers have the same spatial orientation with distinct anisotropy, approaching a dichroic ratio (DR) of 8. Polarization-sensitive light absorption is due to the uniaxially oriented polymer chains, which are dominated by lamellar packing with edge-on orientation. For IPPDs based on this anisotropic all-polymer heterojunction film, a photocurrent anisotropy was found with a polarized photocurrent ratio of 2.6. The detectivity of these IPPDs was found to be 1.9 × 1011 Jones (@ ∼600 nm, 0 V bias). Our work shows that oriented polymer donor-acceptor films fabricated using bottom-up self-assembly have great potential in applications, such as polarization detection.
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| 13. |
- Shen, Manqiong, et al.
(författare)
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Interplay Between the Object and Its Symbol : The Size-Congruency Effect
- 2016
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Ingår i: Advances in Cognitive Psychology. - : University of Economics and Human Sciences in Warsaw. - 1895-1171. ; 12:2, s. 115-129
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Tidskriftsartikel (refereegranskat)abstract
- Grounded cognition suggests that conceptual processing shares cognitive resources with perceptual processing. Hence, conceptual processing should be affected by perceptual processing, and vice versa. The current study explored the relationship between conceptual and perceptual processing of size. Within a pair of words, we manipulated the font size of each word, which was either congruent or incongruent with the actual size of the referred object. In Experiment 1a, participants compared object sizes that were referred to by word pairs. Higher accuracy was observed in the congruent condition (e. g., word pairs referring to larger objects in larger font sizes) than in the incongruent condition. This is known as the size-congruency effect. In Experiments 1b and 2, participants compared the font sizes of these word pairs. The size-congruency effect was not observed. In Experiments 3a and 3b, participants compared object and font sizes of word pairs depending on a task cue. Results showed that perceptual processing affected conceptual processing, and vice versa. This suggested that the association between conceptual and perceptual processes may be bidirectional but further modulated by semantic processing. Specifically, conceptual processing might only affect perceptual processing when semantic information is activated. The current study suggests that some grounded phenomena may be modulated by semantic processes.
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| 14. |
- Wang, Yuhang, et al.
(författare)
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Purification and characterization of recombinant human bile salt-stimulated lipase expressed in milk of transgenic cloned cows
- 2017
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Ingår i: PLOS ONE. - : PUBLIC LIBRARY SCIENCE. - 1932-6203. ; 12:5
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Tidskriftsartikel (refereegranskat)abstract
- Bile salt-stimulated lipase (BSSL) is a lipolytic digestive enzyme with broad substrate specificity secreted from exocrine pancreas into the intestinal lumen in all species and from the lactating mammary gland into the milk of some species, notably humans but not cows. BSSL in breast milk facilitates digestion and absorption of milk fat and promotes growth of small for gestational age preterm infants. Thus, purified recombinant human BSSL (rhBSSL) can be used for treatment of patients with fat malabsorption and expressing rhBSSL in the milk of transgenic cloned cows would therefore be a mean to meet a medical need. In the present study, a vector pBAC-hLF-hBSSL was constructed, which efficiently expressed active rhBSSL in milk of transgenic cloned cows to a concentration of 9.8 mg/ml. The rhBSSL purified from cow milk had the same enzymatic activity, N-terminal amino acid sequence, amino acid composition and isoelectric point and similar physicochemical characteristics as human native BSSL. Our study supports the use of transgenic cattle for the cost-competitive, large-scale production of therapeutic rhBSSL.
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| 15. |
- Wei, Ting, et al.
(författare)
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Developed and developing world responsibilities for historical climate change and CO2 mitigation
- 2012
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 109:32, s. 12911-12915
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Tidskriftsartikel (refereegranskat)abstract
- At the United Nations Framework Convention on Climate Change Conference in Cancun, in November 2010, the Heads of State reached an agreement on the aim of limiting the global temperature rise to 2 degrees C relative to preindustrial levels. They recognized that long-term future warming is primarily constrained by cumulative anthropogenic greenhouse gas emissions, that deep cuts in global emissions are required, and that action based on equity must be taken to meet this objective. However, negotiations on emission reduction among countries are increasingly fraught with difficulty, partly because of arguments about the responsibility for the ongoing temperature rise. Simulations with two earth-system models (NCAR/CESM and BNU-ESM) demonstrate that developed countries had contributed about 60-80%, developing countries about 20-40%, to the global temperature rise, upper ocean warming, and sea-ice reduction by 2005. Enacting pledges made at Cancun with continuation to 2100 leads to a reduction in global temperature rise relative to business as usual with a 1/3-2/3 (CESM 33-67%, BNU-ESM 35-65%) contribution from developed and developing countries, respectively. To prevent a temperature rise by 2 degrees C or more in 2100, it is necessary to fill the gap with more ambitious mitigation efforts.
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| 16. |
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| 17. |
- Yuan, Wenping, et al.
(författare)
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Differentiating moss from higher plants is critical in studying the carbon cycle of the boreal biome.
- 2014
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Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 5
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Tidskriftsartikel (refereegranskat)abstract
- The satellite-derived normalized difference vegetation index (NDVI), which is used for estimating gross primary production (GPP), often includes contributions from both mosses and vascular plants in boreal ecosystems. For the same NDVI, moss can generate only about one-third of the GPP that vascular plants can because of its much lower photosynthetic capacity. Here, based on eddy covariance measurements, we show that the difference in photosynthetic capacity between these two plant functional types has never been explicitly included when estimating regional GPP in the boreal region, resulting in a substantial overestimation. The magnitude of this overestimation could have important implications regarding a change from a current carbon sink to a carbon source in the boreal region. Moss abundance, associated with ecosystem disturbances, needs to be mapped and incorporated into GPP estimates in order to adequately assess the role of the boreal region in the global carbon cycle.
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| 18. |
- Zhang, Zhenzong, et al.
(författare)
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Unveiling the role of Ag-Sb bimetallic S-scheme heterojunction for vis-NIR-light driven selective photoreduction CO2 to CH4
- 2022
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Ingår i: Applied Catalysis B: Environmental. - : Elsevier BV. - 0926-3373. ; 319
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Tidskriftsartikel (refereegranskat)abstract
- The construction of interfacial engineered heterojunctions is an effective strategy to broaden the optical response and facilitate charge separation. Herein, a novel 0D/1D Ag2S/Sb2S3 heterojunction is prepared by in-situ growth of Ag2S quantum dots on Sb2S3 nanorods using a simple hydrothermal approach. The 10% Ag2S/Sb2S3 (10AS) heterojunction exhibited efficient CO2 photoreduction activity with a CH4 yield of 6.75 µmol g−1 h−1, which is six times higher than that of pure Sb2S3 NTs. The CH4 selectivity of the 10AS heterojunction reach 96.1%, owing to the construction of dual-metal sites. Intriguingly, the composite photocatalyst could be extended to infrared light, leading to the full utilization of the incident light. In the 10AS heterojunction, the formation of Ag-S-Sb type covalent bonds is demonstrated by Raman and XAFS tests. The pathways of CO2 conversion to CH4 are discussed in detail. Therefore, the work provides a promising strategy for highly selective and efficient CO2 photoreduction.
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