| 1. |
- Proletov, Ian, et al.
(författare)
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Primary and secondary glomerulonephritides 1.
- 2014
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Ingår i: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. - : Oxford University Press (OUP). - 1460-2385. ; 29 Suppl 3:May, s. 186-200
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Tidskriftsartikel (refereegranskat)
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| 2. |
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| 3. |
- Coppo, Rosanna, et al.
(författare)
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Is there long-term value of pathology scoring in immunoglobulin A nephropathy? : A validation study of the Oxford Classification for IgA Nephropathy (VALIGA) update
- 2020
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Ingår i: Nephrology, Dialysis and Transplantation. - : Oxford University Press (OUP). - 0931-0509 .- 1460-2385. ; 35:6, s. 1002-1009
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Tidskriftsartikel (refereegranskat)abstract
- Background: It is unknown whether renal pathology lesions in immunoglobulin A nephropathy (IgAN) correlate with renal outcomes over decades of follow-up.Methods: In 1130 patients of the original Validation Study of the Oxford Classification for IgA Nephropathy (VALIGA) cohort, we studied the relationship between the MEST score (mesangial hypercellularity, M; endocapillary hypercellularity, E; segmental glomerulosclerosis, S; tubular atrophy/interstitial fibrosis, T), crescents (C) and other histological lesions with both a combined renal endpoint [50% estimated glomerular filtration rate (eGFR) loss or kidney failure] and the rate of eGFR decline over a follow-up period extending to 35 years [median 7 years (interquartile range 4.1-10.8)].Results: In this extended analysis, M1, S1 and T1-T2 lesions as well as the whole MEST score were independently related with the combined endpoint (P < 0.01), and there was no effect modification by age for these associations, suggesting that they may be valid in children and in adults as well. Only T lesions were associated with the rate of eGFR loss in the whole cohort, whereas C showed this association only in patients not treated with immunosuppression. In separate prognostic analyses, the whole set of pathology lesions provided a gain in discrimination power over the clinical variables alone, which was similar at 5 years (+2.0%) and for the whole follow-up (+1.8%). A similar benefit was observed for risk reclassification analyses (+2.7% and +2.4%).Conclusion: Long-term follow-up analyses of the VALIGA cohort showed that the independent relationship between kidney biopsy findings and the risk of progression towards kidney failure in IgAN remains unchanged across all age groups and decades after the renal biopsy.
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| 4. |
- Lundberg, Dan, et al.
(författare)
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Inclusion of a single-tail amino acid-based amphiphile in a lipoplex formulation: Effects on transfection efficiency and physicochemical properties
- 2011
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Ingår i: Molecular Membrane Biology. - : Informa UK Limited. - 0968-7688 .- 1464-5203. ; 28:1, s. 42-53
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Tidskriftsartikel (refereegranskat)abstract
- Effects of the addition of a cationic amino acid-based synthetic amphiphile, arginine N-lauroyl amide dihydrochloride (ALA), to a lipid-based transfection formulation have been investigated. It is shown that the inclusion of ALA results in a substantial enhancement of the transfection capability of lipoplexes prepared with liposomes of 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine and cholesterol, which themselves mediate highly efficient transfection. A possible explanation for the increased biological activity is that ALA adsorbed to the surface of the DNA-lipid complexes is involved in triggering internalization. However, in order to identify possible additional factors underlying the enhanced transfection efficiency, the physical properties of formulations with and without ALA were characterized using cryo-transmission electron microscopy, dynamic light scattering, and an ethidium bromide intercalation assay. ALA seems to have limited influence on the initial internal structure of the complexes and the protection of DNA, but its presence is found to decrease the average effective size of the dispersed particles; this change in size may be important in improving the biological activity. Furthermore, ALA can act to influence the transfection efficiency of the formulation by promoting the release of DNA following internalization in the transfected cells.
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| 5. |
- Porpino, Suenia K. P., et al.
(författare)
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Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II-mediated hypertension
- 2016
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Ingår i: British Journal of Pharmacology. - : Wiley. - 0007-1188 .- 1476-5381. ; 173:14, s. 2290-2302
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Tidskriftsartikel (refereegranskat)abstract
- Background and PurposeNO deficiency and oxidative stress are crucially involved in the development or progression of cardiovascular disease, including hypertension and stroke. We have previously demonstrated that acute treatment with the newly discovered organic nitrate, 2-nitrate-1,3-dibuthoxypropan (NDBP), is associated with NO-like effects in the vasculature. This study aimed to further characterize the mechanism(s) and to elucidate the therapeutic potential in a model of hypertension and oxidative stress. Experimental ApproachA combination of ex vivo, in vitro and in vivo approaches was used to assess the effects of NDBP on vascular reactivity, NO release, NADPH oxidase activity and in a model of hypertension. Key ResultsEx vivo vascular studies demonstrated NDBP-mediated vasorelaxation in mesenteric resistance arteries, which was devoid of tolerance. In vitro studies using liver and kidney homogenates revealed dose-dependent and sustained NO generation by NDBP, which was attenuated by the xanthine oxidase inhibitor febuxostat. In addition, NDBP reduced NADPH oxidase activity in the liver and prevented angiotensin II-induced activation of NADPH oxidase in the kidney. In vivo studies showed that NDBP halted the progression of hypertension in mice with chronic angiotensin II infusion. This was associated with attenuated cardiac hypertrophy, and reduced NADPH oxidase-derived oxidative stress and fibrosis in the kidney and heart. Conclusion and ImplicationsThe novel organic nitrate NDBP halts the progression of angiotensin II-mediated hypertension. Mechanistically, our findings suggest that NDBP treatment is associated with sustained NO release and attenuated activity of NADPH oxidase, which to some extent requires functional xanthine oxidase.
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| 6. |
- Dengjel, Joern, et al.
(författare)
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Identification of Autophagosome-associated Proteins and Regulators by Quantitative Proteomic Analysis and Genetic Screens
- 2012
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Ingår i: Molecular & Cellular Proteomics. - 1535-9476 .- 1535-9484. ; 11:3
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Tidskriftsartikel (refereegranskat)abstract
- Autophagy is one of the major intracellular catabolic pathways, but little is known about the composition of autophagosomes. To study the associated proteins, we isolated autophagosomes from human breast cancer cells using two different biochemical methods and three stimulus types: amino acid deprivation or rapamycin or concanamycin A treatment. The autophagosome- associated proteins were dependent on stimulus, but a core set of proteins was stimulus- independent. Remarkably, proteasomal proteins were abundant among the stimulus- independent common autophagosome- associated proteins, and the activation of autophagy significantly decreased the cellular proteasome level and activity supporting interplay between the two degradation pathways. A screen of yeast strains defective in the orthologs of the human genes encoding for a common set of autophagosome- associated proteins revealed several regulators of autophagy, including subunits of the retromer complex. The combined spatiotemporal proteomic and genetic data sets presented here provide a basis for further characterization of autophagosome biogenesis and cargo selection.
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| 7. |
- Gudjonsson, Sigurdur, et al.
(författare)
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The Value of the UroVysion((R)) Assay for Surveillance of Non-Muscle-Invasive Bladder Cancer.
- 2008
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Ingår i: European Urology. - : Elsevier BV. - 1873-7560 .- 0302-2838. ; 54:2, s. 402-408
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: Patients with non-muscle-invasive bladder cancer are traditionally followed by repeat cystoscopy and urine cytology. A fluorescence in situ hybridisation technique called UroVysion((R)) (UV) is now available for clinical diagnosis of urothelial cancer cells. The aim of the present study was to compare UV analysis with routine follow-up methods. METHODS: We studied an unselected cohort of patients undergoing cystoscopy follow-ups at two Swedish centres in 2004-2005. All patients were investigated by cystoscopy, cytology, and UV assay. The UV assay was evaluated with regards to sensitivity, specificity, and positive predictive value for tumour recurrence. RESULTS: In all, 159 cases were analysed. UV had a 30% overall sensitivity for the 27 biopsy-proven recurrences and 70% sensitivity for high-risk tumours (pT1 and carcinoma in situ [CIS]). The specificity of UV was 95%. UV detected all six CIS cases in the study and was predictive in two additional patients who developed CIS within 1 yr of inclusion. Cytology was positive in four of those eight CIS cases and atypical in the other four. CONCLUSIONS: The UV assay cannot replace cystoscopy for surveillance of patients with non-muscle-invasive bladder cancer, but it may be valuable as a supplement to traditional measures for detecting CIS. Before any conclusions can be drawn regarding the efficacy of novel markers of bladder cancer, they must be studied in bladder cancer patients undergoing endoscopic surveillance.
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| 8. |
- Gustafsson Lundberg, Johanna, et al.
(författare)
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Feministisk etik
- 2011
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Ingår i: Kön, teologi och etik : en introduktion. - 9789144057460 ; , s. 107-142
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Bokkapitel (refereegranskat)
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| 9. |
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| 10. |
- Hossein Abbasi, Mohammad, et al.
(författare)
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Haunted by shadows of the future : ARTEFACTS
- 2014
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Annan publikation (populärvet., debatt m.m.)abstract
- Haunted by Shadows of the Future: ARTEFACTS identifierar föremål från slutet av1960-talet till slutet av 1970-talet som har ett personligt eller familjärt samband medmänniskorna och samhället under denna tid, och som innefattar en särskild känslaav tillhörighet, en önskan att vara en del av det moderna svenska samhälle som togform vid den tiden. Resultatet av detta kollektiva sökande är en samling artefakter,företeelser och föremål i hemmet, sammanflätade med rika personliga berättelser ochupptäckter. Dessa inbegriper en försäkringsförsäljares portfölj, en rullbandspelaresom fångade ett populärt radioprogram med en pratshow, en inspelning med enlandsflyktig somalisk författare, tidiga exemplar av plastleksaker, diabilder frånsemestrar, vykortssamlingar och super 8 filmer, textiltryck med popmönster ochmönster för klädesplagg, lokala grönplanteringar, en affärskedjas lansering av ettanti-varumärke, den revolutionerande ”du”-reformen, och andra samtida referenser,som ett svenskt kvinnomanifest och en populär oljevärmare från Iran. Stadsmuseetsvisningslägenhet i Tensta på Kämpingebacken 13, tjänar här som en tidskapsel somöppnar en hel värld bakom dessa YTTERST vardagliga föremål.
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| 11. |
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| 12. |
- Jernsand, Eva Maria, 1967, et al.
(författare)
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An Introduction: Tourism, Knowledge and Learning
- 2022
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Ingår i: Tourism, Knowledge and Learning. - London and New York : Routledge. - 9781003293316 ; , s. 1-8
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Bokkapitel (refereegranskat)abstract
- In this chapter, the editors of the book introduce the reader to learning in a sustainable tourism context. Learning and personal development have emerged as motivations and interests in tourism and travel, in line with societal and market changes. This transformation relates to, for instance, the climate crisis, the Covid-19 pandemic, rapid technological developments, and the fact that travellers are more experienced, knowledgable and aware. Learning and the collaborative production of knowledge is also seen as a necessity for dealing with threats to climate, biodiversity, welfare, security and democracy. The purpose of this book is to explore how tourism, knowledge and learning can be used as means towards sustainable development through current, new or changed structures, concepts, activities and communication efforts. In this first chapter, we also outline the main theoretical concepts of the book, and the conceptual, empirical and methodological contributions of each chapter.
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| 13. |
- Jernsand, Eva Maria, 1967, et al.
(författare)
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Towards a research agenda on tourism, knowledge and learning
- 2022
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Ingår i: Tourism, Knowledge and Learning. - London and New York : Routledge. - 9781003293316 ; , s. 113-119
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Bokkapitel (refereegranskat)abstract
- This chapter reconnects to the book’s theoretical starting point: experience-based and transformational learning. We then synthesize the results from the chapters under four themes: from passive to active, from analogue to digital, from generic to target group-adapted, and from fragmented to inclusive. Under each theme, we discuss prospects and limitations and suggest research avenues. As several of the chapters highlight the need to develop how learning experiences are created and organized, we encourage future research to address issues that can inform research and practice about 1) the role of the tourists in creating learning experiences, 2) the impacts of the digital transition, 3) the adaptation of tourism offers to tourists’ prior knowledge and preferences, and 4) the role of collaboration.
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| 14. |
- Karlberg, Maria, et al.
(författare)
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Mixed solutions of an associating polymer with a cleavable surfactant
- 2005
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Ingår i: Langmuir. - : American Chemical Society (ACS). - 0743-7463 .- 1520-5827. ; 21:21, s. 9756-9763
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Tidskriftsartikel (refereegranskat)abstract
- Mixtures of hydrophobically modified hydroxyethyl cellulose (HMHEC) and alkali-sensitive cleavable betaine ester surfactants have been studied by viscometry, H-1 NMR, absorbance measurements, and birefringence determinations. Before the hydrolysis, the surfactants behaved as conventional nondegradable surfactants in terms of the effect on the viscosity of increasing surfactant concentration. As the surfactants were hydrolyzed, systems with time-dependent viscosity were obtained. The viscosity either decreased monotonically or went through a maximum as a function of time, depending on the initial surfactant concentration. Different surfactant chain lengths gave rise to different viscosity profiles. The rate of hydrolysis, and thus the time-dependency of the surfactant concentration, could be controlled by changing the pH of the solution.
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| 15. |
- Levin, Malin, 1973, et al.
(författare)
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Rip2 deficiency leads to increased atherosclerosis despite decreased inflammation.
- 2011
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Ingår i: Circulation research. - 1524-4571. ; 109:11, s. 1210-8
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Tidskriftsartikel (refereegranskat)abstract
- The innate immune system and in particular the pattern-recognition receptors Toll-like receptors have recently been linked to atherosclerosis. Consequently, inhibition of various signaling molecules downstream of the Toll-like receptors has been tested as a strategy to prevent progression of atherosclerosis. Receptor-interacting protein 2 (Rip2) is a serine/threonine kinase that is involved in multiple nuclear factor-κB (NFκB) activation pathways, including Toll-like receptors, and is therefore an interesting potential target for pharmaceutical intervention.
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| 16. |
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| 17. |
- Lincke, Alisa, 1989-, et al.
(författare)
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Diabetes Information in Social Media
- 2018
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Ingår i: Proceedings of the 11th International Symposium on Visual Information Communication and Interaction (VINCI '18). - New York, NY, USA : ACM Publications. - 9781450365017 ; , s. 104-105
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Konferensbidrag (refereegranskat)abstract
- Social media platforms have created new ways for people to communicate and express themselves. Thus, it is important to explore how e-health related information is generated and disseminated in these platforms. The aim of our current efforts is to investigate the content and flow of information when people in Sweden use Twitter to talk about diabetes related issues. To achieve our goals, we have used data mining and visualization techniques in order to explore, analyze and cluster Twitter data we have collected during a period of 10 months. Our initial results indicate that patients use Twitter to share diabetes related information and to communicate about their disease as an alternative way that complements the traditional channels used by health care professionals.
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| 18. |
- Lohmander, Anette, et al.
(författare)
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Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 4. Speech outcomes in 5-year-olds - velopharyngeal competency and hypernasality
- 2017
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Ingår i: Journal of Plastic Surgery and Hand Surgery. - : TAYLOR & FRANCIS LTD. - 2000-656X .- 2000-6764. ; 51:1, s. 27-37
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Tidskriftsartikel (refereegranskat)abstract
- Background and aim: Adequate velopharyngeal function and speech are main goals in the treatment of cleft palate. The objective was to investigate if there were differences in velopharyngeal competency (VPC) and hypernasality at age 5 years in children with unilateral cleft lip and palate (UCLP) operated on with different surgical methods for primary palatal repair. A secondary aim was to estimate burden of care in terms of received additional secondary surgeries and speech therapy. Design: Three parallel group, randomised clinical trials were undertaken as an international multicentre study by 10 cleft teams in five countries: Denmark, Finland, Sweden, Norway, and the UK. Methods: Three different surgical protocols for primary palatal repair were tested against a common procedure in the total cohort of 448 children born with a non-syndromic UCLP. Speech audio and video recordings of 391 children (136 girls, 255 boys) were available and perceptually analysed. The main outcome measures were VPC and hypernasality from blinded assessments. Results: There were no statistically significant differences between the prevalences in the arms in any of the trials. VPC: Trial 1, A: 58%, B: 61%; Trial 2, A: 57%, C: 54%; Trial 3, A: 35%, D: 51%. No hypernasality: Trial 1, A: 54%, B: 44%; Trial 2, A: 47%, C: 51%; Trial 3, A: 34%, D: 49%. Conclusions: No differences were found regarding VPC and hypernasality at age 5 years after different methods for primary palatal repair. The burden of care in terms of secondary pharyngeal surgeries, number of fistulae, and speech therapy visits differed.
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| 19. |
- Lundberg, Christina, et al.
(författare)
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Age and sex differences in cause-specific excess mortality and years of life lost associated with COVID-19 infection in the Swedish population
- 2023
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Ingår i: European Journal of Public Health. - : OXFORD UNIV PRESS. - 1101-1262 .- 1464-360X. ; 33:5, s. 916-22
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Tidskriftsartikel (refereegranskat)abstract
- Background Estimating excess mortality and years of life lost (YLL) attributed to coronavirus disease 19 (COVID-19) infection provides a comprehensive picture of the mortality burden on society. We aimed to estimate the impact of the COVID-19 pandemic on age- and sex-specific excess mortality and YLL in Sweden during the first 17 months of the pandemic. Methods In this population-based observational study, we calculated age- and sex-specific excess all-cause mortality and excess YLL during 2020 and the first 5 months of 2021 and cause-specific death [deaths from cardiovascular disease (CVD), cancer, other causes and deaths excluding COVID-19] in 2020 compared with an average baseline for 2017-19 in the whole Swedish population. Results COVID-19 deaths contributed 9.9% of total deaths (98 441 deaths, 960 305 YLL) in 2020, accounting for 75 151 YLL (7.7 YLL/death). There were 2672 (5.7%) and 1408 (3.0%) excess deaths, and 19 141 (3.8%) and 3596 (0.8%) excess YLL in men and women, respectively. Men aged 65-110 years and women aged 75-110 years were the greatest contributors. Fewer deaths and YLL from CVD, cancer and other causes were observed in 2020 compared with the baseline adjusted to the population size in 2020. Conclusions Compared with the baseline, excess mortality and YLL from all causes were experienced in Sweden during 2020, with a higher excess observed in men than in women, indicating that more men died at a younger age while more women died at older ages than expected. A notable reduction in deaths and YLL due to CVD suggests a displacement effect from CVD to COVID-19.
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| 20. |
- Lundberg, Erik, 1978, et al.
(författare)
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Science tourism: a conceptual development
- 2022
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Ingår i: Tourism, Knowledge and Learning Conceptual Development and Case Studies. Edited By: Eva Maria Jernsand, Maria Persson, Erik Lundberg. - London and New York : Routledge. - 9781003293316 ; , s. 26-39
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Bokkapitel (refereegranskat)abstract
- Science tourism is an activity where people travel to learn about science and gain scientific knowledge and in some cases to participate in scientific research. This chapter provides an expanded conceptualization of science tourism that includes the role of researchers and scientific institutions in co-creating experiences of science tourism. The conceptual model can be used as an analytical lens to understand suppliers’ degree of embeddedness in tourism and science, and how the suppliers, through their activities, make it possible for tourists to immerse themselves in science tourism activities. In addition, the model helps tourism practitioners to strategically position themselves in this growing market.
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| 21. |
- Mak, Jonathan K. L., et al.
(författare)
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Development of an Electronic Frailty Index for Hospitalized Older Adults in Sweden
- 2022
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Ingår i: The journals of gerontology. Series A, Biological sciences and medical sciences. - : Oxford University Press. - 1079-5006 .- 1758-535X. ; 77:11, s. 2311-2319
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Tidskriftsartikel (refereegranskat)abstract
- Background Frailty assessment in the Swedish health system relies on the Clinical Frailty Scale (CFS), but it requires training, in-person evaluation, and is often missing in medical records. We aimed to develop an electronic frailty index (eFI) from routinely collected electronic health records (EHRs) and assess its association with adverse outcomes in hospitalized older adults. Methods EHRs were extracted for 18 225 patients with unplanned admissions between 1 March 2020 and 17 June 2021 from 9 geriatric clinics in Stockholm, Sweden. A 48-item eFI was constructed using diagnostic codes, functioning and other health indicators, and laboratory data. The CFS, Hospital Frailty Risk Score, and Charlson Comorbidity Index were used for comparative assessment of the eFI. We modeled in-hospital mortality and 30-day readmission using logistic regression; 30-day and 6-month mortality using Cox regression; and length of stay using linear regression. Results Thirteen thousand one hundred and eighty-eight patients were included in analyses (mean age 83.1 years). A 0.03 increment in the eFI was associated with higher risks of in-hospital (odds ratio: 1.65; 95% confidence interval: 1.54-1.78), 30-day (hazard ratio [HR]: 1.43; 1.38-1.48), and 6-month mortality (HR: 1.34; 1.31-1.37) adjusted for age and sex. Of the frailty and comorbidity measures, the eFI had the highest area under receiver operating characteristic curve for in-hospital mortality of 0.813. Higher eFI was associated with longer length of stay, but had a rather poor discrimination for 30-day readmission. Conclusions An EHR-based eFI has robust associations with adverse outcomes, suggesting that it can be used in risk stratification in hospitalized older adults.
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| 22. |
- Mak, Jonathan K. L., et al.
(författare)
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Two Years with COVID-19 : The Electronic Frailty Index Identifies High-Risk Patients in the Stockholm GeroCovid Study
- 2023
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Ingår i: Gerontology. - : S. Karger. - 0304-324X .- 1423-0003. ; 69:4, s. 396-405
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Frailty, a measure of biological aging, has been linked to worse COVID-19 outcomes. However, as the mortality differs across the COVID-19 waves, it is less clear whether a medical record-based electronic frailty index (eFI) that we have previously developed for older adults could be used for risk stratification in hospitalized COVID-19 patients. Objectives: The aim of the study was to examine the association of frailty with mortality, readmission, and length of stay in older COVID-19 patients and to compare the predictive accuracy of the eFI to other frailty and comorbidity measures. Methods: This was a retrospective cohort study using electronic health records (EHRs) from nine geriatric clinics in Stockholm, Sweden, comprising 3,980 COVID-19 patients (mean age 81.6 years) admitted between March 2020 and March 2022. Frailty was assessed using a 48-item eFI developed for Swedish geriatric patients, the Clinical Frailty Scale, and the Hospital Frailty Risk Score. Comorbidity was measured using the Charlson Comorbidity Index. We analyzed in-hospital mortality and 30-day readmission using logistic regression, 30-day and 6-month mortality using Cox regression, and the length of stay using linear regression. Predictive accuracy of the logistic regression and Cox models was evaluated by area under the receiver operating characteristic curve (AUC) and Harrell's C-statistic, respectively. Results: Across the study period, the in-hospital mortality rate decreased from 13.9% in the first wave to 3.6% in the latest (Omicron) wave. Controlling for age and sex, a 10% increment in the eFI was significantly associated with higher risks of in-hospital mortality (odds ratio = 2.95; 95% confidence interval = 2.42-3.62), 30-day mortality (hazard ratio [HR] = 2.39; 2.08-2.74), 6-month mortality (HR = 2.29; 2.04-2.56), and a longer length of stay (beta-coefficient = 2.00; 1.65-2.34) but not with 30-day readmission. The association between the eFI and in-hospital mortality remained robust across the waves, even after the vaccination rollout. Among all measures, the eFI had the best discrimination for in-hospital (AUC = 0.780), 30-day (Harrell's C = 0.733), and 6-month mortality (Harrell's C = 0.719). Conclusion: An eFI based on routinely collected EHRs can be applied in identifying high-risk older COVID-19 patients during the continuing pandemic.
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| 23. |
- Moberg, Christina, et al.
(författare)
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De unga gör helt rätt när de stämmer staten
- 2022
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Ingår i: Aftonbladet. - 1103-9000.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
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| 24. |
- Persdotter, Maria, et al.
(författare)
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Rätten till en skälig levnadsnivå i förhandling
- 2023
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Ingår i: De sociala rättigheternas politik. - 9789151109855 ; , s. 85-85
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Ett detta kapitel som behandlar sociala rättigheter i ett domstolssammanhang analyseras domstolars betydelsefulla roll när det gäller att uttolka och använda begreppet skälig levnadsnivå, som ett sätt att både omförhandla och utveckla rättigheter.
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| 25. |
- Persson, Maria, 1976, et al.
(författare)
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Kunskapsturism som kan utveckla besöksnäringen : #21 NYFIKEN
- 2022
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Vilka är egentligen anledningarna till att vi reser? Nöjen, eskapism och avkoppling är starka ”hedoniska” (som ger oss njutning) resemotiv som utgör ryggraden för besöksnäring och turism. Andra mer ”eudaemoniska” resemotiv som lärande och personlig utveckling har hittills setts som mer perifera nischmarknader. Men en förändring är på gång. Klimatkrisen, frågor om samhälls- och hållbar utveckling, covid-pandemin och resenärer som är mer erfarna, kunniga och medvetna än någonsin tidigare håller på att ändra efterfrågan. Resenärerna önskar upplevelser som relaterar till de värderingar de har, man vill lära sig något och utvecklas som individer. Rapporten NYFIKEN handlar om turism som på olika sätt har lärande som syfte. Den summerar forskningsprojektet Kunskapsturism som attraktion och resurs som genomförts av forskare vid Centrum för turism, Göteborgs universitet. Projektet visar på att kunskap bör ses både som attraktion och som resurs för hållbar destinationsutveckling. Studien tar sin utgångspunkt i två typer av lärande: upplevelsebaserat och transformativt (begreppen förklaras närmare i kapitel 2). Då alltfler besökare efterfrågar lärandeupplevelser finns potential för destinationer att utveckla högkvalitativa kunskapsbaserade turismupplevelser och genom det bidra till hållbar utveckling. Kunskapsturism äger rum i både bebyggd miljö i form av museer, akvarier och djurparker, samt i natur-, kultur- och industrimiljöer som kulturarv, naturreservat och nationalparker. I rapporten ger forskarna tre exempel på upplevelsekoncept inom kunskapsturism: Biosfärområden, Marina kolonilotter och Scary seafood. Science tourism (vetenskapsturism) är en specifik form av kunskapsturism direkt eller indirekt kopplad till forskningsverksamhet. I vissa fall kan turister och besökare också bidra till forskningen genom sitt deltagande (så kallad medborgarforskning). Det är ett sätt att demokratisera kunskap genom att öppna upp i många fall sluten forskning och expertkunskap för att ge andra möjlighet att bidra till och också påverka vetenskaplig kunskap. Den globala utvecklingen och utmaningarna som följer av den ställer krav på nya strategier som främjar kunskapsutveckling om hållbar utveckling och kollektivt lärande. Detta är nödvändigt för att kunna transformera det globala turismsystemet till att gå i takt med FN:s Agenda 2030 och de globala hållbarhetsmålen. De omfattar att hantera hot mot både klimat och biologisk mångfald, välfärd, säkerhet och demokrati. Genom att utveckla kunskapsturism kopplat till destinationer kan besöksnäringen bidra aktivt till ett mer hållbart samhälle. Centralt i detta är samskapande mellan olika aktörer. Det behövs en bredare och fördjupad samverkan mellan besöksnäringens medarbetare, akademin och offentlig sektor för att bygga förståelse, kunskap och färdigheter och för att utveckla koncept för kunskapsturism.
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| 26. |
- Robertson, Josefina, et al.
(författare)
-
Body Mass Index in Young Women and Risk of Cardiomyopathy: A Long-Term Follow-Up Study in Sweden
- 2020
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Ingår i: Circulation. - 0009-7322. ; 141:7, s. 520-529
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Incidence rates of cardiomyopathies, which are a common cause of heart failure in young people, have increased during the last decades. An association between body weight in adolescence and future cardiomyopathy among men was recently identified. Whether or not this holds true also for women is unknown. The aim was therefore to determine whether for young women being overweight or obese is associated with a higher risk of developing cardiomyopathy. METHODS: This was a registry-based national prospective cohort study with data collected from the Swedish Medical Birth Register, 1982 to 2014, with up to 33 years of follow-up. Included women were of childbearing age (18-45 years) during the initial antenatal visit in their first or second pregnancy (n=1393 346). We obtained baseline data on body mass index (BMI), smoking, education, and previous disorders. After exclusions, mainly because of previous disorders, the final sample was composed of 1388 571 women. Cardiomyopathy cases were identified by linking the Medical Birth Register to the National Patient and Cause of Death registers. RESULTS: In total, we identified 1699 cases of cardiomyopathy (mean age at diagnosis, 46.2 [SD 9.1] years) during the follow-up with an incidence rate of 5.9 per 100000 observation years. Of these, 481 were diagnosed with dilated cardiomyopathy, 246 had hypertrophic cardiomyopathy, 61 had alcohol/drug-induced cardiomyopathy, and 509 had other forms. The lowest risk for being diagnosed with a cardiomyopathy was detected at a BMI of 21 kg/m2, with a gradual increase in risk with higher BMI, particularly for dilated cardiomyopathy, where a hazard ratio of 4.71 (95% CI, 2.81-7.89) was found for severely obese subjects (BMI ≥35 kg/m2), as compared with BMI 20 to <22.5. CONCLUSIONS: Elevated BMI among young women was associated with an increased risk of being diagnosed with a subsequent cardiomyopathy, especially dilated cardiomyopathy, starting already at mildly elevated body weight, whereas severe obesity entailed an almost 5-fold increase in risk. With the increasing numbers of persons who are overweight or obese, higher rates of cardiomyopathy can be expected in the future, along with an altered disease burden related to adiposity.
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| 27. |
- Rosengren, Annika, 1951, et al.
(författare)
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COVID-19 in people aged 18–64 in Sweden in the first year of the pandemic: Key factors for severe disease and death
- 2022
-
Ingår i: Global Epidemiology. - : Elsevier BV. - 2590-1133. ; 4
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Studies on risk factors for severe COVID-19 in people of working age have generally not included non-working persons or established population attributable fractions (PAFs) for occupational and other factors. Objectives: We describe the effect of job-related, sociodemographic, and other exposures on the incidence, relative risks and PAFs of severe COVID-19 in individuals aged 18–64. Methods: We conducted a registry-based study in Swedish citizens aged 18–64 from 1 January 2020 to 1 February 2021 with respect to COVID-19-related hospitalizations and death. Results: Of 6,205,459 persons, 272,043 (7.5%) were registered as infected, 3399 (0.05%) needed intensive care, and 620 (0.01%) died, with an estimated case fatality rate of 0.06% over the last 4-month period when testing was adequate. Non-Nordic origin was associated with a RR for need of intensive care of 3·13, 95%CI 2·91–3·36, and a PAF of 32·2% after adjustment for age, sex, work, region and comorbidities. In a second model with occupation as main exposure, and adjusted for age, sex, region, comorbidities and origin, essential workers had an RR of 1·51, 95%CI, 1·35–1·6, blue-collar workers 1·18, 95%CI 1·06–1·31, school staff 1·21, 95%CI 1·01–1·46, and health and social care workers 1·89, 95%CI 1·67–2·135) compared with people able to work from home, with altogether about 13% of the PAF associated with these occupations. Essential workers and blue-collar workers, but no other job categories had higher risk of death, adjusted RRs of 1·79, 95%CI 1·34–2·38 and 1·37, 95%CI 1·04–1·81, with adjusted PAFs of altogether 9%. Conclusion: Among people of working age in Sweden, overall mortality and case fatality were low. Occupations that require physical presence at work were associated with elevated risk of needing intensive care for COVID-19, with 14% cases attributable to this factor, and 9% of deaths.
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| 28. |
- Rosengren, Annika, 1951, et al.
(författare)
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Severe COVID-19 in people 55 and older during the first year of the pandemic in Sweden
- 2022
-
Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796 .- 0955-7873. ; 292:4, s. 641-653
-
Tidskriftsartikel (refereegranskat)abstract
- Background Exposure to many contacts is the main risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, while risk of serious disease and death is chiefly determined by old age and comorbidities. Relative and population-attributable fractions (PAFs) of multiple medical and social exposures for COVID-19 outcomes have not been evaluated among older adults. Objectives We describe the effect of multiple exposures on the odds of testing positive for the virus and of severe disease (hospital care or death) and PAFs in Swedish citizens aged 55 years and above. Methods We used national registers to follow all citizens aged 55 years and above with respect to (1) testing positive, (2) hospitalization, and (3) death between 31 January 2020 and 1 February 2021. Results Of 3,410,241 persons, 156,017 (4.6%, mean age 68.3 years) tested positive for SARS-CoV-2, while 35,999 (1.1%, mean age 76.7 years) were hospitalized or died (12,384 deaths, 0.4%, mean age 84.0 years). Among the total cohort, the proportion living without home care or long-term care was 98.8% among persons aged 55-64 and 22.1% of those aged 95 and above. After multiple adjustment, home care and long-term care were associated with odds ratios of 7.9 (95% confidence interval [CI] 6.8-9.1) and 22.5 (95% CI 19.6-25.7) for mortality, with PAFs of 21.9% (95% CI 20.9-22.9) and 33.3% (95% CI 32.4-34.3), respectively. Conclusion Among Swedish residents aged 55 years and above, those with home care or long-term care had markedly increased risk for COVID-19 death during the first year of the pandemic, with over 50% of deaths attributable to these factors.
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| 29. |
- Semb, Gunvor, et al.
(författare)
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A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
- 2017
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Ingår i: Journal of Plastic Surgery and Hand Surgery. - : Taylor & Francis. - 2000-656X .- 2000-6764. ; 51:1, s. 2-13
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIMS: Longstanding uncertainty surrounds the selection of surgical protocols for the closure of unilateral cleft lip and palate, and randomised trials have only rarely been performed. This paper is an introduction to three randomised trials of primary surgery for children born with complete unilateral cleft lip and palate (UCLP). It presents the protocol developed for the trials in CONSORT format, and describes the management structure that was developed to achieve the long-term engagement and commitment required to complete the project.METHOD: Ten established national or regional cleft centres participated. Lip and soft palate closure at 3-4 months, and hard palate closure at 12 months served as a common method in each trial. Trial 1 compared this with hard palate closure at 36 months. Trial 2 compared it with lip closure at 3-4 months and hard and soft palate closure at 12 months. Trial 3 compared it with lip and hard palate closure at 3-4 months and soft palate closure at 12 months. The primary outcomes were speech and dentofacial development, with a series of perioperative and longer-term secondary outcomes.RESULTS: Recruitment of 448 infants took place over a 9-year period, with 99.8% subsequent retention at 5 years.CONCLUSION: The series of reports that follow this introductory paper include comparisons at age 5 of surgical outcomes, speech outcomes, measures of dentofacial development and appearance, and parental satisfaction. The outcomes recorded and the numbers analysed for each outcome and time point are described in the series.TRIAL REGISTRATION: ISRCTN29932826.
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| 30. |
- Starck, Göran, et al.
(författare)
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A 1H magnetic resonance spectroscopy study in adults with obsessive compulsive disorder: relationship between metabolite concentrations and symptom severity.
- 2008
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Ingår i: Journal of neural transmission (Vienna, Austria : 1996). - : Springer Science and Business Media LLC. - 0300-9564 .- 1435-1463. ; 115:7, s. 1051-62
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Tidskriftsartikel (refereegranskat)abstract
- 1H magnetic resonance spectroscopy (1H MRS) studies exploring brain metabolites, especially glutamine + glutamate (Glx), in obsessive compulsive disorder (OCD) are of vital interest for trying to understand more about the pathophysiology of OCD. Therefore, we conducted the present 1H MRS study with the aims of (1) comparing MRS metabolites in a group of adult patients with OCD and a group of healthy controls, and (2) examining the relationship between MRS metabolite concentrations and symptom severity in the patient group. Three brain regions were studied, the right caudate nucleus, the anterior gyrus cinguli and the occipital cortex bilaterally. Since multivariate analysis is a highly useful tool for extraction of 1H MRS data, we applied principal component analysis (PCA) and partial least square projection to latent structures (PLS) to the MRS data. PLS disclosed a strong relationship between several of the metabolites and OCD symptom severity, as measured with Yale-Brown obsessive-compulsive scale (YBOCS): the YBOCS score was found to be positively correlated to caudate creatine, Glx, glutamate, and choline compounds as well as occipital cortex myoinositol, and negatively correlated to occipital cortex Glx. The negative correlation between occipital cortex Glx and YBOCS was the most impressive. PCA did not reveal any tendency for a separation between the patients with OCD and controls with respect to MRS metabolites. The results are discussed in relation to corticostriatothalamocortical feedback and previous observations of poor visuospatial ability in OCD.
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| 31. |
-
Tourism, Knowledge and Learning
- 2022
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Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)abstract
- This book contributes to the understanding of how tourism can be designed to provide conditions for learning. This involves learning for tourists, the tourist industry, public authorities and local communities. We explore how tourism, knowledge and learning can be used as means towards sustainable development through current, new or changed structures, concepts, activities and communication efforts. The book should be seen as both an inspiration for tourism actors (e.g. tourism attractions, policy makers and other industry actors). and a scholarly contribution to further research. A holistic approach distinguishes this book from most existing literature that focuses on separate units of tourism, for instance, personal or community well-being, nature-based tourism, cultural heritage tourism, or tourism that is a result of researchers's travels (so called scientific tourism). The various contributors to the book provide a range of perspectives and experiences, from social sciences with a focus on marketing, innovation management, human geography and environmental law, to arts and humanities with a focus on heritage studies, archaeology and photography, and, finally, to natural sciences with a focus on marine sciences.
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| 32. |
- Willadsen, Elisabeth, et al.
(författare)
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Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 5. Speech outcomes in 5-year-olds - consonant proficiency and errors
- 2017
-
Ingår i: Journal of Plastic Surgery and Hand Surgery. - : TAYLOR & FRANCIS LTD. - 2000-656X .- 2000-6764. ; 51:1, s. 38-51
-
Tidskriftsartikel (refereegranskat)abstract
- Background and aim: Normal articulation before school start is a main objective in cleft palate treatment. The aim was to investigate if differences exist in consonant proficiency at age 5 years between children with unilateral cleft lip and palate (UCLP) randomised to different surgical protocols for primary palatal repair. A secondary aim was to estimate burden of care in terms of received additional secondary surgeries and speech therapy. Design: Three parallel group, randomised clinical trials were undertaken as an international multicentre study by 10 cleft teams in five countries: Denmark, Finland, Norway, Sweden, and the UK. Methods: Three different surgical protocols for primary palatal repair were tested against a common procedure in the total cohort of 448 children born with non-syndromic UCLP. Speech audio- and video-recordings of 391 children (136 girls and 255 boys) were available and transcribed phonetically. The main outcome measure was Percent Consonants Correct (PCC) from blinded assessments. Results: In Trial 1, arm A showed statistically significant higher PCC scores (82%) than arm B (78%) (p=.045). No significant differences were found between prevalences in Trial 2, A: 79%, C: 82%; or Trial 3, A: 80%, D: 85%. Across all trials, girls achieved better PCC scores, excluding s-errors, than boys (91.0% and 87.5%, respectively) (p=.01). Conclusions: PCC scores were higher in arm A than B in Trial 1, whereas no differences were found between arms in Trials 2 or 3. The burden of care in terms of secondary pharyngeal surgeries, number of fistulae, and speech therapy visits differed.
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| 33. |
- Zillinger, Malin, et al.
(författare)
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Learning on guided tours: historical perspectives
- 2022
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Ingår i: Tourism, knowledge and learning : Conceptual development and case studies - Conceptual development and case studies. - London : Routledge. ; , s. 40-57
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 34. |
- Aad, G., et al.
(författare)
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Evidence for the Higgs Boson Decay to a Z Boson and a Photon at the LHC
- 2024
-
Ingår i: Physical Review Letters. - : American Physical Society (APS). - 0031-9007 .- 1079-7114. ; 132:2
-
Tidskriftsartikel (refereegranskat)abstract
- The first evidence for the Higgs boson decay to a Z boson and a photon is presented, with a statistical significance of 3.4 standard deviations. The result is derived from a combined analysis of the searches performed by the ATLAS and CMS Collaborations with proton-proton collision datasets collected at the CERN Large Hadron Collider (LHC) from 2015 to 2018. These correspond to integrated luminosities of around 140 fb−1 for each experiment, at a center-of-mass energy of 13 TeV. The measured signal yield is 2.2±0.7 times the standard model prediction, and agrees with the theoretical expectation within 1.9 standard deviations.
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| 35. |
- Aad, G., et al.
(författare)
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Fast b-tagging at the high-level trigger of the ATLAS experiment in LHC Run 3
- 2023
-
Ingår i: Journal of Instrumentation. - : Institute of Physics. - 1748-0221. ; 18:11
-
Tidskriftsartikel (refereegranskat)abstract
- The ATLAS experiment relies on real-time hadronic jet reconstruction and b-tagging to record fully hadronic events containing b-jets. These algorithms require track reconstruction, which is computationally expensive and could overwhelm the high-level-trigger farm, even at the reduced event rate that passes the ATLAS first stage hardware-based trigger. In LHC Run 3, ATLAS has mitigated these computational demands by introducing a fast neural-network-based b-tagger, which acts as a low-precision filter using input from hadronic jets and tracks. It runs after a hardware trigger and before the remaining high-level-trigger reconstruction. This design relies on the negligible cost of neural-network inference as compared to track reconstruction, and the cost reduction from limiting tracking to specific regions of the detector. In the case of Standard Model HH → bb̅bb̅, a key signature relying on b-jet triggers, the filter lowers the input rate to the remaining high-level trigger by a factor of five at the small cost of reducing the overall signal efficiency by roughly 2%.
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| 36. |
- Aad, G., et al.
(författare)
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Measurement of the B0s → μμ effective lifetime with the ATLAS detector
- 2023
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Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479. ; 2023:9
-
Tidskriftsartikel (refereegranskat)abstract
- This paper reports the first ATLAS measurement of the → μμ effective lifetime. The measurement is based on the data collected in 2015–2016, amounting to 26.3 fb−1 of 13 TeV LHC proton-proton collisions. The proper decay-time distribution of 58 ± 13 background-subtracted signal candidates is fit with simulated signal templates parameterised as a function of the effective lifetime, with statistical uncertainties extracted through a Neyman construction. The resulting effective measurement of the → μμ lifetime is (stat.) ± 0.17 (syst.) ps and it is found to be consistent with the Standard Model.
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| 37. |
- Aad, G., et al.
(författare)
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Measurement of the H→ γγ and H→ ZZ∗→ 4 ℓ cross-sections in pp collisions at √s=13.6 TeV with the ATLAS detector
- 2024
-
Ingår i: European Physical Journal C. - : Institute for Ionics. - 1434-6044 .- 1434-6052. ; 84:1
-
Tidskriftsartikel (refereegranskat)abstract
- The inclusive Higgs boson production cross-section is measured in the di-photon and the ZZ∗→ 4 ℓ decay channels using 31.4 and 29.0 fb - 1 of pp collision data respectively, collected with the ATLAS detector at a centre-of-mass energy of s=13.6 TeV . To reduce the model dependence, the measurement in each channel is restricted to a particle-level phase space that closely matches the channel’s detector-level kinematic selection, and it is corrected for detector effects. These measured fiducial cross-sections are σfid,γγ= 76-13+14 fb, and σfid,4ℓ= 2.80±0.74 fb, in agreement with the corresponding Standard Model predictions of 67.6 ± 3.7 fb and 3.67 ± 0.19 fb. Assuming Standard Model acceptances and branching fractions for the two channels, the fiducial measurements are extrapolated to the full phase space yielding total cross-sections of σ(pp→H)=67-11+12 pb and 46 ± 12 pb at 13.6 TeV from the di-photon and ZZ∗→ 4 ℓ measurements respectively. The two measurements are combined into a total cross-section measurement of σ(pp→ H) = 58.2 ± 8.7 pb, to be compared with the Standard Model prediction of σ(pp→ H) SM= 59.9 ± 2.6 pb.
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| 38. |
- Aad, G., et al.
(författare)
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Measurement of the production cross-section of J/ψ and ψ(2S) mesons in pp collisions at √s=13 TeV with the ATLAS detector
- 2024
-
Ingår i: European Physical Journal C. - : Springer Nature. - 1434-6044 .- 1434-6052. ; 84:2
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Tidskriftsartikel (refereegranskat)abstract
- Measurements of the differential production cross-sections of prompt and non-prompt ?/? and ?(2S) mesons with transverse momenta between 8 and 360 GeV and rapidity in the range |?|<2 are reported. Furthermore, measurements of the non-prompt fractions of ?/? and ?(2S), and the prompt and non-prompt ?(2S)-to-?/? production ratios, are presented. The analysis is performed using 140 fb−1 of √?=13 TeV pp collision data recorded by the ATLAS detector at the LHC during the years 2015–2018.
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| 39. |
- Aad, G., et al.
(författare)
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Measurement of the t¯t¯ cross section and its ratio to the Z production cross section using pp collisions at √s=13.6 TeV with the ATLAS detector
- 2024
-
Ingår i: Physics Letters B. - : Elsevier. - 0370-2693 .- 1873-2445. ; 848
-
Tidskriftsartikel (refereegranskat)abstract
- The inclusive top-quark-pair production cross section ???̄ and its ratio to the ?-boson production cross section have been measured in proton–proton collisions at √? = 13.6 TeV, using 29 fb−1 of data collected in 2022 with the ATLAS experiment at the Large Hadron Collider. Using events with an opposite-charge electron-muon pair and ?-tagged jets, and assuming Standard Model decays, the top-quark-pair production cross section is measured to be ???̄ = 850± 3(stat.) ± 18(syst.) ± 20(lumi.) pb. The ratio of the ??̄ and the ?-boson production cross sections is also measured, where the ?-boson contribution is determined for inclusive ?+?− and ?+?− events in a fiducial phase space. The relative uncertainty on the ratio is reduced compared to the ??̄ cross section, thanks to the cancellation of several systematic uncertainties. The result for the ratio, ???̄∕? = 1.145 ± 0.003(stat.) ± 0.021(syst.)±0.002(lumi.) is consistent with the Standard Model prediction using the PDF4LHC21 PDF set.
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| 40. |
- Aad, G., et al.
(författare)
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Performance and calibration of quark/gluon-jet taggers using 140 fb-1 of pp collisions at √s=13 TeV with the ATLAS detector
- 2024
-
Ingår i: Chinese Physics C. - : IOP Publishing. - 1674-1137 .- 2058-6132. ; 48:2
-
Tidskriftsartikel (refereegranskat)abstract
- The identification of jets originating from quarks and gluons, often referred to as quark/gluon tagging, plays an important role in various analyses performed at the Large Hadron Collider, as Standard Model measurements and searches for new particles decaying to quarks often rely on suppressing a large gluon-induced background. This paper describes the measurement of the efficiencies of quark/gluon taggers developed within the ATLAS Collaboration, using √?=13 TeV proton–proton collision data with an integrated luminosity of 140 fb−1 collected by the ATLAS experiment. Two taggers with high performances in rejecting jets from gluon over jets from quarks are studied: one tagger is based on requirements on the number of inner-detector tracks associated with the jet, and the other combines several jet substructure observables using a boosted decision tree. A method is established to determine the quark/gluon fraction in data, by using quark/gluon-enriched subsamples defined by the jet pseudorapidity. Differences in tagging efficiency between data and simulation are provided for jets with transverse momentum between 500 GeV and 2 TeV and for multiple tagger working points.
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| 41. |
- Aad, G., et al.
(författare)
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Search for a new heavy scalar particle decaying into a Higgs boson and a new scalar singlet in final states with one or two light leptons and a pair of τ-leptons with the ATLAS detector
- 2023
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479. ; 2023:10
-
Tidskriftsartikel (refereegranskat)abstract
- A search for a new heavy scalar particle X decaying into a Standard Model (SM) Higgs boson and a new singlet scalar particle S is presented. The search uses a proton-proton (pp) collision data sample with an integrated luminosity of 140 fb−1 recorded at a centre-of-mass energy of √s= 13 TeV with the ATLAS detector at the Large Hadron Collider. The most sensitive mass parameter space is explored in X mass ranging from 500 to 1500 GeV, with the corresponding S mass in the range 200–500 GeV. The search selects events with two hadronically decaying τ-lepton candidates from H → τ+τ− decays and one or two light leptons (ℓ = e, μ) from S → VV (V = W, Z) decays while the remaining V boson decays hadronically or to neutrinos. A multivariate discriminant based on event kinematics is used to separate the signal from the background. No excess is observed beyond the expected SM background and 95% confidence level upper limits between 72 fb and 542 fb are derived on the cross-section σ(pp → X → SH) assuming the same SM-Higgs boson-like decay branching ratios for the S → VV decay. Upper limits on the visible cross-sections σ(pp → X → SH → WWττ) and σ(pp → X → SH → ZZττ) are also set in the ranges 3–26 fb and 6–33 fb, respectively.
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| 42. |
- Aad, G., et al.
(författare)
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Search for direct production of electroweakinos in final states with one lepton, jets and missing transverse momentum in pp collisions at √s=13 TeV with the ATLAS detector
- 2023
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479. ; 2023:12
-
Tidskriftsartikel (refereegranskat)abstract
- Searches for electroweak production of wino-like chargino pairs, , and of wino-like chargino and next-to-lightest neutralino, , are presented. The models explored assume that the charginos decay into a W boson and the lightest neutralino, . The next-to-lightest neutralinos are degenerate in mass with the chargino and decay to and either a Z or a Higgs boson, or . The searches exploit the presence of a single isolated lepton and missing transverse momentum from the W boson decay products and the lightest neutralinos, and the presence of jets from hadronically decaying Z or W bosons or from the Higgs boson decaying into a pair of b-quarks. The searches use 139 fb−1 of √s = 13 TeV proton-proton collisions data collected by the ATLAS detector at the Large Hadron Collider between 2015 and 2018. No deviations from the Standard Model expectations are found, and 95% confidence level exclusion limits are set. Chargino masses ranging from 260 to 520 GeV are excluded for a massless in chargino pair production models. Degenerate chargino and next-to-lightest neutralino masses ranging from 260 to 420 GeV are excluded for a massless for . For decays through an on-shell Higgs boson and for mass-splitting between and as small as the Higgs boson mass, mass limits are improved by up to 40 GeV in the range of 200–260 GeV and 280–470 GeV compared to previous ATLAS constraints.
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| 43. |
- Aad, G., et al.
(författare)
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Search for Majorana neutrinos in same-sign WW scattering events from pp collisions at √s=13 TeV
- 2023
-
Ingår i: European Physical Journal C. - : Institute for Ionics. - 1434-6044 .- 1434-6052. ; 83:9
-
Tidskriftsartikel (refereegranskat)abstract
- A search for Majorana neutrinos in same-sign WW scattering events is presented. The analysis uses √s=13 TeV proton–proton collision data with an integrated luminosity of 140 fb−1 recorded during 2015–2018 by the ATLAS detector at the Large Hadron Collider. The analysis targets final states including exactly two same-sign muons and at least two hadronic jets well separated in rapidity. The modelling of the main backgrounds, from Standard Model same-sign WW scattering and WZ production, is constrained with data in dedicated signal-depleted control regions. The distribution of the transverse momentum of the second-hardest muon is used to search for signals originating from a heavy Majorana neutrino with a mass between 50 GeV and 20 TeV. No significant excess is observed over the background expectation. The results are interpreted in a benchmark scenario of the Phenomenological Type-I Seesaw model. In addition, the sensitivity to the Weinberg operator is investigated. Upper limits at the 95% confidence level are placed on the squared muon-neutrino–heavy-neutrino mass-mixing matrix element |VμN|2 as a function of the heavy Majorana neutrino’s mass mN, and on the effective μμ Majorana neutrino mass |mμμ|.
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| 44. |
- Aad, G., et al.
(författare)
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Search for resonant production of dark quarks in the dijet final state with the ATLAS detector
- 2024
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479. ; 2024:2
-
Tidskriftsartikel (refereegranskat)abstract
- This paper presents a search for a new Z′ resonance decaying into a pair of dark quarks which hadronise into dark hadrons before promptly decaying back as Standard Model particles. This analysis is based on proton-proton collision data recorded at √? = 13 TeV with the ATLAS detector at the Large Hadron Collider between 2015 and 2018, corresponding to an integrated luminosity of 139 fb−1. After selecting events containing large-radius jets with high track multiplicity, the invariant mass distribution of the two highest-transverse-momentum jets is scanned to look for an excess above a data-driven estimate of the Standard Model multijet background. No significant excess of events is observed and the results are thus used to set 95% confidence-level upper limits on the production cross-section times branching ratio of the Z′ to dark quarks as a function of the Z′ mass for various dark-quark scenarios.
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| 45. |
- Abord-Hugon Nonet, Guénola, et al.
(författare)
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PRME Nordic Chapter
- 2021. - 1
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Ingår i: Responsible management education. - London : Routledge. - 9781032030272 - 9781032030296 - 9781003186311 ; , s. 182-197
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Bokkapitel (refereegranskat)
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| 46. |
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| 47. |
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| 48. |
- Aldenius, Maria, et al.
(författare)
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Experimental Mg I oscillator strengths and radiative lifetimes for astrophysical applications on metal-poor stars - New data for the MgI b triplet
- 2007
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Ingår i: Astronomy & Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 461:2, s. 767-773
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Tidskriftsartikel (refereegranskat)abstract
- Context. The stellar abundance ratio of Mg/Fe is an important tool in diagnostics of galaxy evolution. In order to make reliable measurements of the Mg abundance of stars, it is necessary to have accurate values for the oscillator strength (f- value) of each of the observable transitions. In metal-poor stars the MgI 3p-4s triplet around 5175 angstrom (Fraunhofer's so-called b lines) are the most prominent magnesium lines. The lines also appear as strong features in the solar spectrum. Aims. We present new and improved experimental oscillator strengths for the optical MgI 3p-4s triplet, along with experimental radiative lifetimes for six terms in Mg I. With these data we discuss the implications on previous and future abundance analyses of metal-poor stars. Methods. The oscillator strengths have been determined by combining radiative lifetimes with branching fractions, where the radiative lifetimes are measured using the laser induced fluorescence technique and the branching fractions are determined using intensity calibrated Fourier Transform (FT) spectra. The FT spectra are also used for determining new accurate laboratory wavelengths for the 3p-4s transitions. Results. The f-values of the MgI 3p-4s lines have been determined with an absolute uncertainty of 9%, giving an uncertainty of +/- 0.04 dex in the log g f values. Compared to values previously used in abundance analyses of metal-poor stars, rescaling to the new values implies an increase of typically 0.04 dex in the magnesium abundance.
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| 49. |
- Almqvist, Sara, et al.
(författare)
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Fördjupad analys av den svenska klimatomställningen 2020 : Klimat och luft i fokus
- 2020
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Sverige har ambitiösa klimatåtaganden där regeringen uttalat att Sverige ska bli världens första fossilfria välfärdsland. Riksdagen har antagit ambitiösa mål för att minska utsläppen av växthusgaser i Sverige för att vara med i omställningen och begränsa den globala uppvärmningen i linje med Parisavtalet. Under 2017 antog riksdagen ett klimatpolitiskt ramverk för Sverige med nya klimatmål. Det långsiktiga klimatmålet innebär att Sverige senast år 2045 inte ska ha några nettoutsläpp av växthusgaser till atmosfären, för att därefter uppnå negativa utsläpp. Det innebär att utsläppen av växthusgaser inom Sveriges gränser ska ha minskat med minst 85 procent senast år 2045 jämfört med utsläppen år 1990.Naturvårdsverket visar vägen mot klimatmålenNaturvårdsverket ansvarar för uppföljningen av Sveriges nationellt fastställda klimatmål. Årets rapport innehåller fördjupade analyser av trender i den svenska klimatomställningen för Sveriges utsläpp och nettoupptag av växthusgaser och ger en övergripande bild av hur vi befinner oss på vägen mot Sveriges klimatmål. Rapporten innehåller ett särskilt fokuskapitel som beskriver möjligheter med att integrera åtgärdsstrategier i luft- och klimatarbetet.Sveriges utsläpp av växthusgaser minskar för långsamtSveriges territoriella utsläpp av växthusgaser var 50,9 miljoner ton koldioxidekvivalenter år 2019, vilket motsvarar en minskning om 2,4 procent jämfört med 2018. För att nå det långsiktiga klimatmålet om nettonollutsläpp till 2045 krävs en genomsnittlig minskningstakt om 6–10 procent per år från 2019.Det senaste årets utsläppsminskning beror främst på minskade utsläpp inom industrisektorn och el- och fjärrvärmesektorn. Inom industrin har utsläppen framför allt minskat på grund av planerade underhållsstopp på raffinaderier och minskad produktion inom mineralindustrin. Minskade utsläpp syns i de flesta sektorerna, förutom jordbrukssektorn och arbetsmaskiner där utsläppen har ökat jämfört med föregående år.
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