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- Lundgren, Tord, et al.
(författare)
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Periodontal treatment of patients with Papillon-Lefèvre syndrome : a 3-year follow-up
- 2004
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Ingår i: Journal of Clinical Periodontology. - 0303-6979 .- 1600-051X. ; 31:11, s. 933-938
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND/AIM: Conventional mechanical periodontal treatment of Papillon-Lefevre syndrome (PLS) has often been reported to fail. This study describes the outcome of a non-surgical periodontal therapy including antimicrobial treatment of nine patients diagnosed with PLS. The patients originate from a total of 15 children and adolescents with PLS for which clinical characteristics are presented.METHODS: Clinical examination including conventional periodontal measurements. Initial treatment including oral hygiene instruction, scaling and root planing and systemic amoxicillin-metronidazole therapy for 6 weeks. After that the patients were enrolled in a 3-month recall maintenance program. In addition to this mechanical supportive maintenance treatment, tetracycline was prescribed and used continuously for 1.5 years.RESULTS/CONCLUSION: On five patients who were showing acceptable standard of oral hygiene and also compliance with the antibiotic medication, development of periodontitis on erupting teeth was prevented and disease activity on the previously periodontally involved teeth controlled during a 3-year period. Poor results of treatment were observed for three patients, all siblings. These patients failed to comply with the medication and also failed to improve their oral hygiene.
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| 2. |
- Ahlberg, Erik, et al.
(författare)
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"Vi klimatforskare stödjer Greta och skolungdomarna"
- 2019
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Ingår i: Dagens nyheter (DN debatt). - 1101-2447.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- DN DEBATT 15/3. Sedan industrialiseringens början har vi använt omkring fyra femtedelar av den mängd fossilt kol som får förbrännas för att vi ska klara Parisavtalet. Vi har bara en femtedel kvar och det är bråttom att kraftigt reducera utsläppen. Det har Greta Thunberg och de strejkande ungdomarna förstått. Därför stödjer vi deras krav, skriver 270 klimatforskare.
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| 6. |
- Kuklane, Kalev, et al.
(författare)
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Insulation of traditional Indian clothing: Estimation of climate change impact on productivity from PHS (predicted heat strain) model
- 2014
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Ingår i: Achieving Sustainable Construction Health and Safety : proceedings of CIB W099 International Conference, 2-3 June 2014, Lund University, Sweden - proceedings of CIB W099 International Conference, 2-3 June 2014, Lund University, Sweden. - 9789176230053 ; , s. 234-244
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Konferensbidrag (refereegranskat)abstract
- Major databases on western clothing and their thermal properties are available, but information on non-western clothing is lacking. A recent ASHRAE project 1504 TRP, Extension of the Clothing Insulation Database for Standard 55 and ISO 7730 dealt with the issue. Simultaneously, a co-operation study at Indian workplaces allowed us to acquire some sets of the traditional clothes used at construction sites in Chennai area. The work was related to mapping of present work conditions in order to allow predictions and measures to be taken if the mean temperature of the work environment would rise. We selected ISO 7933 on predicted heat strain (PHS) as a tool to estimate productivity loss in physical work. PHS criteria are related to reaching safe body core temperature limit of 38 °C or excess water loss. 3 sets of clothing were investigated: 2 female sets of traditional clothes (churidar and saree) modified as used at construction site (added shirt and towel to protect traditional clothes and hair), and a male set commonly used at the construction sites. The clothing insulation and evaporative resistance were measured on thermal manikins. The climatic conditions were based on weather statistics, and metabolic heat production was based on field observations at work places and the ISO 8996:2004 tables (Ergonomics of the thermal environment — Determination of metabolic rate). For the future scenarios all basic parameters were left the same except the air temperature was increased by 2 °C. Adding the protective layer on female clothing did increase clothing insulation by 25-31 % and evaporative resistance by 10-18 % respectively. This affected the performance showing lower capacity to maintain work pace already under present climatic conditions. Further increase in mean air temperature may decrease the productivity by 30-80 % depending on the parameter that is observed (limited exposure time or lower work load), and on the earlier capacity to carry out the tasks. The present evaluation may have several limitations related to the PHS model's boundaries, and validation of the presented method application is needed.
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| 7. |
- Lundgren Kownacki, Karin, et al.
(författare)
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Sustainability Challenges from Climate Change and Air Conditioning Use in Urban Areas
- 2013
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Ingår i: Sustainability. - : MDPI AG. - 2071-1050. ; 5:7, s. 3116-3128
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Tidskriftsartikel (refereegranskat)abstract
- Global climate change increases heat loads in urban areas causing health and productivity risks for millions of people. Inhabitants in tropical and subtropical urban areas are at especial risk due to high population density, already high temperatures, and temperature increases due to climate change. Air conditioning is growing rapidly, especially in South and South-East Asia due to income growth and the need to protect from high heat exposures. Studies have linked increased total hourly electricity use to outdoor temperatures and humidity; modeled future predictions when facing additional heat due to climate change, related air conditioning with increased street level heat and estimated future air conditioning use in major urban areas. However, global and localized studies linking climate variables with air conditioning alone are lacking. More research and detailed data is needed looking at the effects of increasing air conditioning use, electricity consumption, climate change and interactions with the urban heat island effect. Climate change mitigation, for example using renewable energy sources, particularly photovoltaic electricity generation, to power air conditioning, and other sustainable methods to reduce heat exposure are needed to make future urban areas more climate resilient.
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| 8. |
- Lundgren, Tord
(författare)
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Papillon Le-Fèvre Syndrome : associations to clinical and laboratory factors and results of treatment
- 2004
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The aim of this thesis was to elucidate factors possibly contributing to the rapidly progressing periodontitis in a group of Papillon-Lefèvre syndrome (PLS) patients and to evaluate a combined mechanical and antimicrobial treatment model in these patients. The total patient sample consisted of 20 individuals referred to King Faisal Specialist Hospital and Research Centre in Saudi Arabia for treatment of PLS. Saliva samples were obtained from 16 patients with the diagnosis of PLS. A control group was selected from healthy siblings and healthy children and young adults from Saudi Arabia. Both the unstimulated and the stimulated whole saliva secretion rates were significantly lower in PLS-patients compared to control individuals (p<0.01 and p< 0.05). The buffer capacity was also significantly lower (p<0.01), whereas IgA and lactoferrin concentrations were significantly higher (p<0.01) in the PLS-group. A significantly lower output was detected for peroxidase when calculating the amount or activity per time among the PLS-patients compared to controls. Subgingival microbial samples were obtained from 36 sites in 12 PLS patients in order to assess the occurrence of 18 different microbial species. Actinobacillus actinomycetemcomitans and P. gingivalis were only infrequently encountered in high levels in the subgingival samples whereas B. forsythus, T.denticola, P. intermedia and C. rectus reached high levels (≥10 6cells) in more then 50% of all patients. The results of the study indicate that there is no specific profile of the subgingival microflora in PLS patients. Blood samples were obtained from all 20 PLS individuals and from an equal number of healthy volunteers. Natural Killer cells (NK cells) from the PLS subjects exhibited significantly reduced cytotoxicity against K562 cells compared to controls (p<0.0001). NK cell cytotoxicity was severely depressed and was the only finding that was consistent among all PLS subjects. To evaluate the effect of retinoid treatment on the periodontal health nine participants that had received systemic retinoid medication for different length of time were compared to nine PLS patients with no such medication. The clinical data revealed no obvious difference in periodontal conditions between the retinoid-medication-group and the non-medication-group. Nine dentate PLS patients were subjected to an intensive mechanical and antimicrobial treatment regimen. Extractions were performed of teeth considered untreatable and periodontal treatment was initiated with non-surgical treatment during 6 weeks.The patients were prescribed to use amoxicillin (250 mg twice/day) and metronidazole (250-500 mg three times/day). After the initial 6-week treatment period, all patients were scheduled for maintenance care every 3 months. In addition to this mechanical maintenance treatment, tetracycline (250 mg/day) was prescribed and used continuously for 1.5 years. For teeth erupting during the 3-year observation period no lesion ≥6 mm had developed in 5 patients. In 3 patients demonstrating an unsuccessful treatment result the periodontal disease progressed on existing teeth and developed on several teeth erupting during the observation period. The 5 patients presenting an excellent or good treatment result all complied with the antibiotic treatment. It was concluded that a combined mechanical and antimicrobial periodontal treatment may lead to preservation of a periodontally healthy and functional dentition over several years.
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