| 1. |
- Allentoft, Morten E., et al.
(författare)
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100 ancient genomes show repeated population turnovers in Neolithic Denmark
- 2024
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Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 625, s. 329-337
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Tidskriftsartikel (refereegranskat)abstract
- Major migration events in Holocene Eurasia have been characterized genetically at broad regional scales1–4. However, insights into the population dynamics in the contact zones are hampered by a lack of ancient genomic data sampled at high spatiotemporal resolution5–7. Here, to address this, we analysed shotgun-sequenced genomes from 100 skeletons spanning 7,300 years of the Mesolithic period, Neolithic period and Early Bronze Age in Denmark and integrated these with proxies for diet (13C and 15N content), mobility (87Sr/86Sr ratio) and vegetation cover (pollen). We observe that Danish Mesolithic individuals of the Maglemose, Kongemose and Ertebølle cultures form a distinct genetic cluster related to other Western European hunter-gatherers. Despite shifts in material culture they displayed genetic homogeneity from around 10,500 to 5,900 calibrated years before present, when Neolithic farmers with Anatolian-derived ancestry arrived. Although the Neolithic transition was delayed by more than a millennium relative to Central Europe, it was very abrupt and resulted in a population turnover with limited genetic contribution from local hunter-gatherers. The succeeding Neolithic population, associated with the Funnel Beaker culture, persisted for only about 1,000 years before immigrants with eastern Steppe-derived ancestry arrived. This second and equally rapid population replacement gave rise to the Single Grave culture with an ancestry profile more similar to present-day Danes. In our multiproxy dataset, these major demographic events are manifested as parallel shifts in genotype, phenotype, diet and land use.
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| 2. |
- Allentoft, Morten E., et al.
(författare)
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Population genomics of post-glacial western Eurasia
- 2024
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Ingår i: Nature. - 0028-0836 .- 1476-4687. ; 625:7994, s. 301-311
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Tidskriftsartikel (refereegranskat)abstract
- Western Eurasia witnessed several large-scale human migrations during the Holocene1–5. Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced 317 genomes—mainly from the Mesolithic and Neolithic periods—from across northern and western Eurasia. These were imputed alongside published data to obtain diploid genotypes from more than 1,600 ancient humans. Our analyses revealed a ‘great divide’ genomic boundary extending from the Black Sea to the Baltic. Mesolithic hunter-gatherers were highly genetically differentiated east and west of this zone, and the effect of the neolithization was equally disparate. Large-scale ancestry shifts occurred in the west as farming was introduced, including near-total replacement of hunter-gatherers in many areas, whereas no substantial ancestry shifts happened east of the zone during the same period. Similarly, relatedness decreased in the west from the Neolithic transition onwards, whereas, east of the Urals, relatedness remained high until around 4,000 bp, consistent with the persistence of localized groups of hunter-gatherers. The boundary dissolved when Yamnaya-related ancestry spread across western Eurasia around 5,000 bp, resulting in a second major turnover that reached most parts of Europe within a 1,000-year span. The genetic origin and fate of the Yamnaya have remained elusive, but we show that hunter-gatherers from the Middle Don region contributed ancestry to them. Yamnaya groups later admixed with individuals associated with the Globular Amphora culture before expanding into Europe. Similar turnovers occurred in western Siberia, where we report new genomic data from a ‘Neolithic steppe’ cline spanning the Siberian forest steppe to Lake Baikal. These prehistoric migrations had profound and lasting effects on the genetic diversity of Eurasian populations.
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| 3. |
- Ahlström, Torbjörn, et al.
(författare)
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Från kaos till kosmos
- 2008
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Ingår i: Biologisk antropologi med human osteologi. - 9788702030372 ; , s. 167-169
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 4. |
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| 5. |
- Ceciliason, Ann-Sofie, 1971-
(författare)
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Forensic taphonomy in an indoor setting : Implications for estimation of the post-mortem interval
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The overall aim of this thesis was to determine if and how taphonomic data can be used to expand our knowledge concerning the decompositional process in an indoor setting, as well as adapting scoring-based methods for quantification of human decomposition, to increase the precision of post-mortem interval (PMI) estimates.In the first paper, the established methods of Total Body Score (TBS) and Accumulated Degree-Days (ADD) were investigated in an indoor setting, with results indicating a fairly low precision. The PMI was often underestimated in cases with desiccation and overestimated in cases with presence of insect activity. This suggests that the TBS method needs to be slightly modified to better reflect the indoor decompositional process.In the second paper, a novel method for PMI estimation was developed using histological assessment of decompositional changes in the human liver. The scoring-based method created, the Hepatic Decomposition Score, was a statistically robust way to quantify the degree of decomposition, with the potential to improve the precision of PMI estimates.In the third paper, the indoor decomposition process was further investigated regarding microbial neoformation of volatiles in relation to the degree of decomposition and the PMI. A higher decomposition degree was observed in cases with neoformation (i.e., presence of N-propanol and/or 1-butanol in femoral vein blood) than in cases without signs of neoformation. Microbial neoformation may be an indicator of decomposition rate, which may make it possible to improve the precision of PMI estimates based on the TBS/ADD method.In the fourth paper, a novel constructed Bayesian framework allowed a qualified estimate of PMI based on observed taphonomic findings. This framework provided a unique possibility to report results, express the uncertainties in assumptions and calculations, as well as to evaluate competing hypotheses regarding PMI periods or time of death.Taken as a whole, the results indicate that using taphonomic data derived from an indoor setting could improve scoring-based methods, as well as highlighting benefits of incorporating such data into a Bayesian framework for interpretational purposes and for reporting PMI estimates.
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| 6. |
- Colville-Ebeling, Bonnie, et al.
(författare)
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Autopsy practice in forensic pathology - Evidence-based or experience-based? : A review of autopsies performed on victims of traumatic asphyxia in a mass disaster
- 2014
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Ingår i: Journal of Forensic and Legal Medicine. - : Elsevier BV. - 1752-928X .- 1878-7487. ; 22, s. 33-36
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Tidskriftsartikel (refereegranskat)abstract
- Current autopsy practice in forensic pathology is to a large extent based on experience and individual customary practices as opposed to evidence and consensus based practices. As a result there is the potential for substantial variation in how knowledge is applied in each case. In the present case series, we describe the variation observed in autopsy reports by five different pathologists of eight victims who died simultaneously from traumatic asphyxia due to compression during a human stampede. We observed that there was no mention of the availability of medical charts in five of the reports, of potentially confounding resuscitation efforts in three reports, of cardinal signs in seven reports and of associated injuries to a various degree in all reports. Further, there was mention of supplemental histological examination in two reports and of pre-autopsy radiograph in six reports. We inferred that reliance on experience and individual customary practices led to disparities between the autopsy reports as well as omissions of important information such as cardinal signs, and conclude that such reliance increases the potential for error in autopsy practice. We suggest that pre-autopsy data-gathering and the use of check lists specific to certain injury causes are likely to result in less deviation from evidence-based practices in forensic pathology. Pre-autopsy data-gathering and check lists will help ensure a higher degree of standardization in autopsy reports thus enhancing the quality and accuracy of the report as a legal document as well as rendering it more useful for data-gathering efforts. (C) 2013 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.
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| 7. |
- Eriksson, Anders, et al.
(författare)
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Dansk-svenskt rättsmedicinskt arbete i Kosovo, 1999. : II. Rättsmedicinska fynd och erfarenheter
- 2000
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Ingår i: Nordisk Rettsmedicin - Scandinavian Journal of Forensic Science. ; 6, s. 74-79
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- På begäran av FN arbetade danska och svenska rättsmedicinska team i Kosovo under sommaren och hösten 1999. Totalt undersöktes 308 kroppar, och då 1-18 månader passerat sedan dödsfallet var kropparna i flertalet fall stadda i avancerad förruttnelse. Arbetet företogs framförallt som mobilt teamarbete med obduktion på platser med 1-5 gravar, men på ett par större gravplatser med 62 respektive 31 döda utfördes arbetet på ett mer traditionellt, stationärt sätt. De flesta avlidna återfanns i separata gravar, ett mindre antal återfanns i gemensamma gravar, medan inga egentliga massgravar blev föremål för våra undersökningar. Huvuduppgiften vid ICTYs utredning av krigsförbrytelser var att fastställa dödsorsaken, medan personidentifiering ansågs vara av sekundär betydelse. Majoriteten av de avlidna var dock identifierade redan före obduktionen.Åldern på de undersökta varierade mellan 5 och 101 år och dominerades av män, vilka företedde en relativt jämn åldersfördelning i åldrarna 20-70 år. Den vanligaste dödsorsaken var skottskador och det vanligaste dödssättet var homicid.Resultatet av undersökningarna har överlämnats till ICTY som en del av bevisningen i de åtal om krigsförbrytelser som kan väntas.
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| 8. |
- Frei, Karin M, et al.
(författare)
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Mapping human mobility during the third and second millennia BC in present-day Denmark
- 2019
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Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 14:8
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Tidskriftsartikel (refereegranskat)abstract
- We present results of the largest multidisciplinary human mobility investigation to date of skeletal remains from present-day Denmark encompassing the 3rd and 2nd millennia BC. Through a multi-analytical approach based on 88 individuals from 37 different archaeological localities in which we combine strontium isotope and radiocarbon analyses together with anthropological investigations, we explore whether there are significant changes in human mobility patterns during this period. Overall, our data suggest that mobility of people seems to have been continuous throughout the 3rd and 2nd millennia BC. However, our data also indicate a clear shift in mobility patterns from around 1600 BC onwards, with a larger variation in the geographical origin of the migrants, and potentially including more distant regions. This shift occurred during a transition period at the beginning of the Nordic Bronze Age at a time when society flourished, expanded and experienced an unprecedented economic growth, suggesting that these aspects were closely related.
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| 9. |
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| 10. |
- Magnell, Ola, et al.
(författare)
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Tafonomi – läran om kvarlevornas historia
- 2008
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Ingår i: Biologisk antropologi med humanosteologi. - 9788702030372 ; , s. 121-146
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 11. |
- Margaryan, Ashot, et al.
(författare)
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Population genomics of the Viking world
- 2020
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 585:7825, s. 390-396
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Tidskriftsartikel (refereegranskat)abstract
- The maritime expansion of Scandinavian populations during the Viking Age (about ad750–1050) was a far-flung transformation in world history1,2. Here we sequenced the genomes of 442humans from archaeological sites across Europe and Greenland (to a median depth of about 1×) to understand the global influence of this expansion. We find the Viking period involved gene flow into Scandinavia from the south and east. We observe genetic structure within Scandinavia, with diversity hotspots in the south and restricted gene flow within Scandinavia. We find evidence for a major influx of Danish ancestry into England; a Swedish influx into the Baltic; and Norwegian influx into Ireland, Iceland and Greenland. Additionally, we see substantial ancestry from elsewhere in Europe entering Scandinavia during the Viking Age. Our ancient DNA analysis also revealed that a Viking expedition included close family members. By comparing with modern populations, we find that pigmentation-associated loci have undergone strong population differentiation during the past millennium, and trace positively selected loci—including the lactase-persistence allele of LCT and alleles of ANKA that are associated with the immune response—in detail. We conclude that the Viking diaspora was characterized by substantial transregional engagement: distinct populations influenced the genomic makeup of different regions of Europe, and Scandinavia experienced increased contact with the rest of the continent.
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| 12. |
- Price, Douglas T., et al.
(författare)
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Isotopic investigation of human provenience at the eleventh century cemetery of Ndr. Grødbygård, Bornholm, Denmark
- 2013
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Ingår i: Danish Journal of Archaeology. - : Det Kgl. Bibliotek/Royal Danish Library. - 2166-2282 .- 2166-2290. ; 1:2, s. 93-112
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Tidskriftsartikel (refereegranskat)abstract
- Bornholm is a Danish island almost in the center of the southern Baltic Sea. The strategic location of the island, its rich archeology, and its complex geology make it an intriguing location for the isotopic study of past human mobility. The focus of this study is on the large cemetery of Ndr. Grødbygård in the southern part of the island, which dates to the eleventh century AD and contains 553 individuals in 516 graves. The majority of the burials were in a supine position oriented west– east, with the heads to the west, following the tradition of that time. In contrast to the Christian traditions, however, the graves at Grødbygård were richly equipped by Scandinavian standards and some of the burial practices more closely resembled those from the Western Slavic region of the south (present day northeastern Germany and Poland). We have used isotopic analyses to examine the external relations and potential places of origin of the inhabitants of the cemetery. Strontium and oxygen isotope ratios in human tooth enamel provide a signature of place of origin and can be compared to the ratios of the place of burial to determine local or non-local origins. In the case of Bornholm, the local geology is quite complex, with a variety of rocks of different age and composition, resulting in a wide range of strontium isotope sources on the island, complicating the issue of identifying migrants. At the same time, Grødbygård provides an important example of the application of such methods in less than ideal conditions.
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| 13. |
- Raghavan, Maanasa, et al.
(författare)
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The genetic prehistory of the New World Arctic
- 2014
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 345:6200, s. 1020-
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Tidskriftsartikel (refereegranskat)abstract
- The New World Arctic, the last region of the Americas to be populated by humans, has a relatively well-researched archaeology, but an understanding of its genetic history is lacking. We present genome-wide sequence data from ancient and present-day humans from Greenland, Arctic Canada, Alaska, Aleutian Islands, and Siberia. We show that Paleo-Eskimos (similar to 3000 BCE to 1300 CE) represent a migration pulse into the Americas independent of both Native American and Inuit expansions. Furthermore, the genetic continuity characterizing the Paleo-Eskimo period was interrupted by the arrival of a new population, representing the ancestors of present-day Inuit, with evidence of past gene flow between these lineages. Despite periodic abandonment of major Arctic regions, a single Paleo-Eskimo metapopulation likely survived in near-isolation for more than 4000 years, only to vanish around 700 years ago.
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