| 1. |
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| 2. |
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| 3. |
- Hopkins, H., et al.
(författare)
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Impact of introduction of rapid diagnostic tests for malaria on antibiotic prescribing: analysis of observational and randomised studies in public and private healthcare settings
- 2017
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Ingår i: Bmj-British Medical Journal. - : BMJ. - 1756-1833 .- 0959-8138. ; 356
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES To examine the impact of use of rapid diagnostic tests for malaria on prescribing of antimicrobials, specifically antibiotics, for acute febrile illness in Africa and Asia. Analysis of nine preselected linked and codesigned observational and randomised studies (eight cluster or individually randomised trials and one observational study). Public and private healthcare settings, 2007-13, in Afghanistan, Cameroon, Ghana, Nigeria, Tanzania, and Uganda. Proportions of patients for whom an antibiotic was prescribed in trial groups who had undergone rapid diagnostic testing compared with controls and in patients with negative test results compared with patients with positive results. A secondary aim compared classes of antibiotics prescribed in different settings. Antibiotics were prescribed to 127 052/238 797 (53%) patients in control groups and 167 714/283 683 (59%) patients in intervention groups. Antibiotics were prescribed to 40% (35 505/89 719) of patients with a positive test result for malaria and to 69% (39 400/57 080) of those with a negative result. All but one study showed a trend toward more antibiotic prescribing in groups who underwent rapid diagnostic tests. Random effects meta-analysis of the trials showed that the overall risk of antibiotic prescription was 21% higher (95% confidence interval 7% to 36%) in intervention settings. In most intervention settings, patients with negative test results received more antibiotic prescriptions than patients with positive results for all the most commonly used classes: penicillins, trimethoprim-sulfamethoxazole (one exception), tetracyclines, and metronidazole. Introduction of rapid diagnostic tests for malaria to reduce unnecessary use of antimalarials-a beneficial public health outcome-could drive up untargeted use of antibiotics. That 69% of patients were prescribed antibiotics when test results were negative probably represents overprescription. This included antibiotics from several classes, including those like metronidazole that are seldom appropriate for febrile illness, across varied clinical, health system, and epidemiological settings. It is often assumed that better disease specific diagnostics will reduce antimicrobial overuse, but they might simply shift it from one antimicrobial class to another. Current global implementation of malaria testing might increase untargeted antibiotic use and must be examined.
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| 4. |
- Jonkman, Nini H., et al.
(författare)
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Do self-management interventions work in patients with heart failure? An individual patient data meta-analysis
- 2016
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Ingår i: Circulation. - : Lippincott Williams & Wilkins. - 0009-7322 .- 1524-4539. ; 133:12, s. 1189-1198
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: -Self-management interventions are widely implemented in care for patients with heart failure (HF). Trials however show inconsistent results and whether specific patient groups respond differently is unknown. This individual patient data meta-analysis assessed the effectiveness of self-management interventions in HF patients and whether subgroups of patients respond differently.METHODS AND RESULTS: -Systematic literature search identified randomized trials of self-management interventions. Data of twenty studies, representing 5624 patients, were included and analyzed using mixed effects models and Cox proportional-hazard models including interaction terms. Self-management interventions reduced risk of time to the combined endpoint HF-related hospitalization or all-cause death (hazard ratio [HR], 0.80; 95% confidence interval [CI], 0.71-0.89), time to HF-related hospitalization (HR, 0.80; 95%CI, 0.69-0.92), and improved 12-month HF-related quality of life (standardized mean difference 0.15; 95%CI, 0.00-0.30). Subgroup analysis revealed a protective effect of self-management on number of HF-related hospital days in patients <65 years (mean number of days 0.70 days vs. 5.35 days; interaction p=0.03). Patients without depression did not show an effect of self-management on survival (HR for all-cause mortality, 0.86; 95%CI, 0.69-1.06), while in patients with moderate/severe depression self-management reduced survival (HR, 1.39; 95%CI, 1.06-1.83, interaction p=0.01).CONCLUSIONS: -This study shows that self-management interventions had a beneficial effect on time to HF-related hospitalization or all-cause death, HF-related hospitalization alone, and elicited a small increase in HF-related quality of life. The findings do not endorse limiting self-management interventions to subgroups of HF patients, but increased mortality in depressed patients warrants caution in applying self-management strategies in these patients.
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| 5. |
- Jonkman, Nini H., et al.
(författare)
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What Are Effective Program Characteristics of Self-Management Interventions in Patients With Heart Failure? : An Individual Patient Data Meta-analysis
- 2016
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Ingår i: Journal of Cardiac Failure. - : Elsevier BV. - 1071-9164 .- 1532-8414. ; 22:11, s. 861-871
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Tidskriftsartikel (refereegranskat)abstract
- Background To identify those characteristics of self-management interventions in patients with heart failure (HF) that are effective in influencing health-related quality of life, mortality, and hospitalizations.Methods and Results Randomized trials on self-management interventions conducted between January 1985 and June 2013 were identified and individual patient data were requested for meta-analysis. Generalized mixed effects models and Cox proportional hazard models including frailty terms were used to assess the relation between characteristics of interventions and health-related outcomes. Twenty randomized trials (5624 patients) were included. Longer intervention duration reduced mortality risk (hazard ratio 0.99, 95% confidence interval [CI] 0.97–0.999 per month increase in duration), risk of HF-related hospitalization (hazard ratio 0.98, 95% CI 0.96–0.99), and HF-related hospitalization at 6 months (risk ratio 0.96, 95% CI 0.92–0.995). Although results were not consistent across outcomes, interventions comprising standardized training of interventionists, peer contact, log keeping, or goal-setting skills appeared less effective than interventions without these characteristics.Conclusion No specific program characteristics were consistently associated with better effects of self-management interventions, but longer duration seemed to improve the effect of self-management interventions on several outcomes. Future research using factorial trial designs and process evaluations is needed to understand the working mechanism of specific program characteristics of self-management interventions in HF patients.
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| 6. |
- Blanco, A., et al.
(författare)
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Performance of timing resistive plate chambers with relativistic neutrons from 300 to 1500 MeV
- 2015
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Ingår i: Journal of Instrumentation. - : IOP Publishing. - 1748-0221. ; 10:2
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Tidskriftsartikel (refereegranskat)abstract
- A prototype composed of four resistive plate chamber layers has been exposed to quasi-monoenergetic neutrons produced from a deuteron beam of varying energy (300 to 1500 AMeV) in experiment S406 at GSI, Darmstad, Germany. Each layer, with an active area of about 2000 × 500 mm2, is made of modules containing the active gaps, all in multigap construction. Each gap is defined by 0.3 mm nylon mono-filaments positioned between 2.85 mm thick float glass electrodes. The modules are operated in avalanche mode with a non-flammable gas mixture composed of 90% C2H2F4 and 10% SF6. The signals are readout by a pick-up electrode formed by 15 copper strips (per layer), spaced at a pitch of 30 mm, connected at both sides to timing front end electronics. Measurements of the time of flight jitter of neutrons, in the mentioned energy range, point to a contribution of the resistive plate chamber in the order of 150 ps, independent of the neutron energy.
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| 7. |
- Bruxvoort, K. J., et al.
(författare)
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The Impact of Introducing Malaria Rapid Diagnostic Tests on Fever Case Management: A Synthesis of Ten Studies from the ACT Consortium
- 2017
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Ingår i: Am J Trop Med Hyg. - : American Society of Tropical Medicine and Hygiene. - 0002-9637 .- 1476-1645. ; 97:4, s. 1170-1179
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Tidskriftsartikel (refereegranskat)abstract
- Since 2010, the World Health Organization has been recommending that all suspected cases of malaria be confirmed with parasite-based diagnosis before treatment. These guidelines represent a paradigm shift away from presumptive antimalarial treatment of fever. Malaria rapid diagnostic tests (mRDTs) are central to implementing this policy, intended to target artemisinin-based combination therapies (ACT) to patients with confirmed malaria and to improve management of patients with nonmalarial fevers. The ACT Consortium conducted ten linked studies, eight in sub-Saharan Africa and two in Afghanistan, to evaluate the impact of mRDT introduction on case management across settings that vary in malaria endemicity and healthcare provider type. This synthesis includes 562,368 outpatient encounters (study size range 2,400-432,513). mRDTs were associated with significantly lower ACT prescription (range 8-69% versus 20-100%). Prescribing did not always adhere to malaria test results; in several settings, ACTs were prescribed to more than 30% of test-negative patients or to fewer than 80% of test-positive patients. Either an antimalarial or an antibiotic was prescribed for more than 75% of patients across most settings; lower antimalarial prescription for malaria test-negative patients was partly offset by higher antibiotic prescription. Symptomatic management with antipyretics alone was prescribed for fewer than 25% of patients across all scenarios. In community health worker and private retailer settings, mRDTs increased referral of patients to other providers. This synthesis provides an overview of shifts in case management that may be expected with mRDT introduction and highlights areas of focus to improve design and implementation of future case management programs.
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| 8. |
- Denison, H, et al.
(författare)
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Diacylglycerol acyltransferase 1 inhibition with AZD7687 alters lipid handling and hormone secretion in the gut with intolerable side effects : a randomized clinical trial
- 2014
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Ingår i: Diabetes, obesity and metabolism. - : Wiley. - 1462-8902 .- 1463-1326. ; 16:4, s. 334-343
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Tidskriftsartikel (refereegranskat)abstract
- AIM:Inhibition of diacylglycerol acyltransferase 1 (DGAT1) is a potential treatment modality for patients with type 2 diabetes mellitus and obesity, based on preclinical data suggesting it is associated with insulin sensitization and weight loss. This randomized, placebo-controlled, phase 1 study in 62 overweight men explored the effects and tolerability of AZD7687, a reversible and selective DGAT1 inhibitor.METHODS:Multiple doses of AZD7687 (1, 2.5, 5, 10 and 20 mg/day, n = 6 or n = 12 for each) or placebo (n = 20) were administered for 1 week. Postprandial serum triacylglycerol (TAG) was measured for 8 hours after a standardized 45% fat meal. Glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) were measured and a paracetamol challenge was performed to assess gastric emptying.RESULTS:Dose-dependent reductions in postprandial serum TAG were demonstrated with AZD7687 doses ≥5 mg compared with placebo (p < 0.01). Significant (p < 0.001) increases in plasma GLP-1 and PYY levels were seen at these doses, but no clear effect on gastric emptying was demonstrated at end of treatment. With AZD7687doses >5 mg/day, gastrointestinal (GI) side effects increased; 11/18 of these participants discontinued treatment owing to diarrhoea.CONCLUSIONS:Altered lipid handling and hormone secretion in the gut were demonstrated during 1-week treatment with the DGAT1 inhibitor AZD7687. However, the apparent lack of therapeutic window owing to GI side effects of AZD7687, particularly diarrhoea, makes the utility of DGAT1 inhibition as a novel treatment for diabetes and obesity questionable.
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| 9. |
- Downs, Robert S. , I I I, et al.
(författare)
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Evaluation of miniature vortex generators for flow control in Falkner-Skan boundary layers
- 2016
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Ingår i: 54th AIAA Aerospace Sciences Meeting. - Reston, Virginia : American Institute of Aeronautics and Astronautics. - 9781624103933
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Konferensbidrag (refereegranskat)abstract
- Vortex generators with heights comparable to displacement thickness are an effective means of producing persistent mean-flow streaks in laminar boundary layers. Inducing streaky base flows can suppress growth of unsteady disturbances which would otherwise incite laminar-to-turbulent transition. Previous experimental and numerical works have demonstrated the versatility of these miniature vortex generators (MVGs) in zero pressure gradient boundary layers. In this work, mean-flow disturbances developing from MVGs in adverse and favorable pressure gradient boundary layers are measured systemically to assess the possibility of extending MVG-based flow control to these scenarios. Boundary-layer streak amplitudes are measured across a range of Falkner-Skan m values and an empirical scaling is found in congruence with existing results. The effect of streaks on transition in an adverse pressure gradient boundary layer is also tested and moderate increases to laminar flow extents are observed.
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| 10. |
- Fransson, Jens H. M., 1973-, et al.
(författare)
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An experimental setup for idealised studies on transition to turbulence on a generic compressor outlet guide vane
- 2018
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Ingår i: Proceedings of the ASME Turbo Expo. - : ASME Press. - 9780791850992
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Konferensbidrag (refereegranskat)abstract
- The understanding of flow phenomena in turbomachinery has come far with respect to three-dimensional flow patterns and pressure distributions. Much is due to improved measurements and a continuously evolving fidelity in computational fluid dynamics (CFD). Turbulence and transition in boundary layers are two classical areas where improvements in modeling are desired and where experimental validation is required. Apart from this, fundamental improvements in efficiency can be obtained by developing experimental resources where technologies affecting transition can be studied. The reduction in friction drag can be considerable if the transition to turbulence can be delayed. An experimental setup in an idealized configuration has been designed and built with the objective to study transition on a very large-scale guide vane profile at low speed. The purpose of the rig is to enable high quality fundamental studies of technologies to delay transition, but also to see how effects of manufacturing or other constraints may affect the boundary layer. In the present paper we report the first validation of the experimental setup, by comparing the first test results to CFD calculations performed during the rig design, i.e. no post-calculations with experimental data as input to the simulations have been done yet. The pressure distribution is in line with the design intent, which is a good indicator that the tunnel design is suitable for the intended purpose. At last we report some velocity measurements performed in the wake and we calculate the total drag based on the wake velocity deficit for various Reynolds numbers and with and without turbulence tripping tape. We illustrate that a two dimensional tripping around 7% of the chord from the leading edge can increase the total drag by 50% with respect to the reference case without tripping tape.
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| 11. |
- Laumert, Björn, 1972-, et al.
(författare)
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Investigation of unsteady aerodynamic blade excitation mechanisms in a transonic turbine stage - Part I : Phenomenological identification and classification
- 2002
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Ingår i: Journal of turbomachinery. - : ASME International. - 0889-504X .- 1528-8900. ; 124:3, s. 410-418
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Tidskriftsartikel (refereegranskat)abstract
- Based on the results of time-dependent 3-D viscous computations the aerodynamic mechanisms that cause the unsteady pressure fluctuations on the vane and rotor blade surface of a high-pressure transonic turbine are identified and separately classified in a phenomenological manner. In order to be able to describe separately the influence of wake, potential and shock distortions on the blade surface pressure tit design operation conditions, the stator exit Mach number is increased as to enhance the shock distortions and lowered as to enhance potential anti wake distortions, In a comprehensive approach the observations from the off-design conditions are utilized to classify every major perturbation observed in the perturbation space-time maps tit design operation conditions. The spanwise variations caused by the inherent 3-D nature of the flow field and promoted by the 3-D shape of the rotor blade are addressed.
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| 12. |
- Laumert, Björn, 1972-, et al.
(författare)
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Investigation of unsteady aerodynamic blade excitation mechanisms in a transonic turbine stage - Part II : Analytical description and quantification
- 2002
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Ingår i: Journal of turbomachinery. - : ASME International. - 0889-504X .- 1528-8900. ; 124:3, s. 419-428
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents a study of the blade pressure perturbation levels and the resulting blade forces in a high-pressure transonic turbine stage based on 3-D time dependent viscous computations. Globally, the blade pressure unsteadiness is quantified with the RMS of the pressure perturbations integrated in both time and along the blade surface. Operation point as well as spanwise variations are addressed. Locally, the relative strength of the pressure perturbation events on the vane and rotor blade surface is investigated. To obtain information about the relative strength of events related to the blade passing frequency and higher harmonics, the pressure field is Fourier decomposed in time at different radial positions along the blade arc-length. The amplitude peaks are then related to the pressure events in space-time maps. With the help of the observations and results from the blade pressure study, the radial variations of the unsteady blade force and torque acting on a constant span blade profile section are investigated. The connection between the first and second vane passing frequency pressure amplitudes on the rotor blade surface and the resulting force and the torque amplitudes for three selected blade modes was investigated in detail. In this investigation the pressure was integrated over defined rotor blade regions to quanti,, local force contributions. Spanwise as well as operation point variations are addressed.
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| 13. |
- Machado, J., et al.
(författare)
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Performance of timing Resistive Plate Chambers with protons from 200 to 800 MeV
- 2015
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Ingår i: Journal of Instrumentation. - 1748-0221. ; 10:1, s. C01043-
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Tidskriftsartikel (refereegranskat)abstract
- A prototype composed of four resistive plate chamber layers has been exposed to quasi-monoenergetic protons produced from a deuteron beam of varying energy (200 to 800 AMeV) in experiment S406 at GSI, Darmstadt, Germany. The aim of the experiment is to characterize the response of the prototype to protons in this energy range, which deposit from 1.75 to 6 times more energy than minimum ionizing particles. Each layer, with an active area of about 2000 × 500 mm 2 , is made of modules containing the active gaps, all in multigap construction. Each gap is defined by 0.3 mm nylon mono-filaments positioned between 2.85 mm thick float glass electrodes. The modules are operated in avalanche mode with a non-flammable gas mixture composed of 90% C 2 H 2 F 4 and 10% SF 6 . The signals are readout by a pick-up electrode formed by 15 copper strips (per layer), spaced at a pitch of 30 mm, connected at both sides to timing front end electronics. Results show an uniform efficiency close to 100% along with a timing resolution of around 60 ps on the entire 2000 × 500 mm 2 area.
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| 14. |
- Mayorca, María A., et al.
(författare)
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A New Reduced Order Modeling for Stability and Forced Response Analysis of Aero-Coupled Blades Considering Various Mode Families
- 2012
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Ingår i: Journal of turbomachinery. - : ASME International. - 0889-504X .- 1528-8900. ; 134:5, s. 051008-
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents the description and application of a new method for stability and forced response analyses of aerodynamically coupled blades considering the interaction of various mode families. The method, here referred as multimode least square, considers the unsteady forces due to the blade motion at different modes shape families and calculates the aerodynamic matrixes by means of a least square (L2) approximations. This approach permits the prediction of mode families' interaction with capabilities of structural, aerodynamic and force mistuning. A projection technique is implemented in order to reduce the computational domain. Application of the method on tuned and structural mistuned forced response and stability analyses is presented on a highly loaded transonic compressor blade. When considering structural mistuning the forced response amplitude magnification is highly affected by the change in aerodynamic damping due to mistuning. Analyses of structural mistuning without aerodynamic coupling might result in over-estimated or under-estimated response when the source of damping is mainly aerodynamic. The frequency split due to mistuning can cause that mode families' interact due to reducing their frequencies separation. The advantage of the present method is that the effect of mode family interaction on aerodynamic damping and forced response is captured not being restricted to single mode families.
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| 15. |
- Mayorca, Maria Angelica, et al.
(författare)
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Prediction of Turbomachinery Aeroelastic Behavior From a Set of Representative Modes
- 2013
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Ingår i: Journal of turbomachinery. - : ASME International. - 0889-504X .- 1528-8900. ; 135:1, s. 011032-
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Tidskriftsartikel (refereegranskat)abstract
- A method is proposed for the determination of the aeroelastic behavior of a system responding to mode-shapes which are different from the tuned in vacuo ones, due to mistuning, mode family interaction, or any other source of mode-shape perturbation. The method is based on the generation of a data base of unsteady aerodynamic forces arising from the motion of arbitrary modes and uses least square approximations for the prediction of any responding mode. The use of a reduced order technique allows for mistuning analyses and is also applied for the selection of a limited number of arbitrary modes. The application of this method on a transonic compressor blade shows that the method captures the aeroelastic properties well in a wide frequency range. A discussion of the influence of the mode-shapes and frequency on the final stability response is also provided.
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| 16. |
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| 17. |
- Sandell, A., et al.
(författare)
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Observation of a low-energy adsorbate core-level satellite for CO bonded to palladium : Coordination-dependent effects
- 1998
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Ingår i: Physical Review B (Condensed Matter). - 0163-1829. ; 57:20, s. 13199-13208
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Tidskriftsartikel (refereegranskat)abstract
- A strong low-energy shake-up satellite for CO adsorbed on Pd is observed. The occurrence of the satellite is established for the CO/1 ML Pd/Mo(110) system at a coverage where CO adsorbs exclusively on-top. Comparisons with CO adsorbed on Pd single-crystal surfaces and small supported Pd particles indicate that the strongly increased satellite intensity is due to the decreased CO-Pd interaction strength for on-top adsorbed CO. This can be used to get further insight into the structure and bonding properties of the adsorbate system. Since a low-energy shake-up feature may be misinterpreted as a chemically shifted component, the conclusion is that great care has to be taken in the evaluation of adsorbate core-level spectra for systems with large variations in adsorption strength depending on the adsorbate sites. Large variations in the CO site distribution may furthermore occur depending on the nature of the Pd substrate: Adsorption of CO on 1 ML Pd/Mo(110) leads to an overlayer dominated by an on-top species and, likewise, the CO overlayer formed on small Pd particles after large doses has a large fraction of on-top bonded species. This is in strong contrast to Pd single-crystal surfaces, where CO adsorbed in more highly coordinated sites is abundant.
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| 18. |
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| 19. |
- Wass, Linda, et al.
(författare)
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Serological reactivity to Anaplasma phagocytophilum in neoehrlichiosis patients
- 2018
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Ingår i: European Journal of Clinical Microbiology & Infectious Diseases. - : Springer Science and Business Media LLC. - 0934-9723 .- 1435-4373. ; 37:9, s. 1673-1678
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Tidskriftsartikel (refereegranskat)abstract
- The tick-borne bacterium Candidatus (Ca.) Neoehrlichia (N.) mikurensis is a cause of "fever of unknown origin" because this strict intracellular pathogen escapes detection by routine blood cultures. Case reports suggest that neoehrlichiosis patients may display serological reactivity to Anaplasma (A.) phagocytophilum. Since Anaplasma serology is part of the diagnostic work-up of undetermined fever in European tick-exposed patients, we wanted to investigate (1) the prevalence of A. phagocytophilum seropositivity among neoehrlichiosis patients, (2) the frequency of misdiagnosed neoehrlichiosis patients among A. phagocytophilum seropositive patients, and (3) the frequency of A. phagocytophilum and Ca. N. mikurensis co-infections. Neoehrlichiosis patients (n = 18) were analyzed for A. phagocytophilum IgM and IgG serum antibodies by indirect immunofluorescence assay. Serum samples from suspected anaplasmosis patients (n = 101) were analyzed for bacterial DNA contents by singleplex PCR specific for A. phagocytophilum and Ca. N. mikurensis, respectively. One fifth of the neoehrlichiosis patients (4/18) were seropositive for IgM and/or IgG to A. phagocytophilum at the time of diagnosis. Among the patients with suspected anaplasmosis, 2% (2/101) were positive for Ca. N. mikurensis by PCR whereas none (0/101) had detectable A. phagocytophilum DNA in the serum. To conclude, patients with suspected anaplasmosis may in fact have neoehrlichiosis. We found no evidence of A. phagocytophilum and Ca. N. mikurensis co-infections in humans with suspected anaplasmosis or confirmed neoehrlichiosis.
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| 20. |
- Wassdahl, N., et al.
(författare)
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Soft x-ray emission studies of adsorbates
- 1992
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Ingår i: Physical Review Letters. - 0031-9007. ; 69:5, s. 812-815
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Tidskriftsartikel (refereegranskat)abstract
- Soft x-ray emission spectroscopy is for the first time applied to surfaces and adsorbates. Surface sensitivity is achieved by employing synchrotron radiation in grazing incidence for the excitation. We present O K emission from adsorbed atomic oxygen on Ni(100) and Cu(100) and molecular CO on Ni(100). The observed spectral features correspond to the occupied 2p partial density of states of the adsorbates.
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| 21. |
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| 22. |
- Aaboud, M, et al.
(författare)
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Measurement of lepton differential distributions and the top quark mass in tt¯ production in pp collisions at √s=8 TeV with the ATLAS detector
- 2017
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Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 77:11
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Tidskriftsartikel (refereegranskat)abstract
- This paper presents single lepton and dilepton kinematic distributions measured in dileptonic tt¯ events produced in 20.2fb - 1 of s=8 TeV pp collisions recorded by the ATLAS experiment at the LHC. Both absolute and normalised differential cross-sections are measured, using events with an opposite-charge eμ pair and one or two b-tagged jets. The cross-sections are measured in a fiducial region corresponding to the detector acceptance for leptons, and are compared to the predictions from a variety of Monte Carlo event generators, as well as fixed-order QCD calculations, exploring the sensitivity of the cross-sections to the gluon parton distribution function. Some of the distributions are also sensitive to the top quark pole mass; a combined fit of NLO fixed-order predictions to all the measured distributions yields a top quark mass value of mtpole=173.2±0.9±0.8±1.2 GeV, where the three uncertainties arise from data statistics, experimental systematics, and theoretical sources. © 2017, CERN for the benefit of the ATLAS collaboration.
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| 23. |
- Aaboud, M, et al.
(författare)
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Search for a Structure in the Bs0 π± Invariant Mass Spectrum with the ATLAS Experiment
- 2018
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Ingår i: Physical Review Letters. - : AMER PHYSICAL SOC. - 1079-7114 .- 0031-9007. ; 120:20
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Tidskriftsartikel (refereegranskat)abstract
- A search for the narrow structure, X(5568), reported by the D0 Collaboration in the decay sequence X→Bs0π±, Bs0→J/ψφ, is presented. The analysis is based on a data sample recorded with the ATLAS detector at the LHC corresponding to 4.9 fb-1 of pp collisions at 7 TeV and 19.5 fb-1 at 8 TeV. No significant signal was found. Upper limits on the number of signal events, with properties corresponding to those reported by D0, and on the X production rate relative to Bs0 mesons, ρX, were determined at 95% confidence level. The results are N(X)
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| 24. |
- Aaboud, M, et al.
(författare)
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Search for Dark Matter Produced in Association with a Higgs Boson Decaying to b b Using 36 fb-1 of pp Collisions at s =13 TeV with the ATLAS Detector
- 2017
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Ingår i: Physical Review Letters. - 1079-7114 .- 0031-9007. ; 119:18
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Tidskriftsartikel (refereegranskat)abstract
- Several extensions of the standard model predict associated production of dark-matter particles with a Higgs boson. Such processes are searched for in final states with missing transverse momentum and a Higgs boson decaying to a bb pair with the ATLAS detector using 36.1 fb-1 of pp collisions at a center-of-mass energy of 13 TeV at the LHC. The observed data are in agreement with the standard model predictions and limits are placed on the associated production of dark-matter particles and a Higgs boson. © 2017 CERN, for the ATLAS Collaboration. Published by the American Physical Society.
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| 25. |
- Aaboud, M, et al.
(författare)
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Search for exclusive Higgs and Z boson decays to ϕγ and ργ with the ATLAS detector
- 2018
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Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2018:7
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Tidskriftsartikel (refereegranskat)abstract
- A search for the exclusive decays of the Higgs and Z bosons to a ϕ or ρ meson and a photon is performed with a pp collision data sample corresponding to an integrated luminosity of up to 35.6 fb−1 collected at s=13 TeV with the ATLAS detector at the CERN Large Hadron Collider. These decays have been suggested as a probe of the Higgs boson couplings to light quarks. No significant excess of events is observed above the background, as expected from the Standard Model. Upper limits at 95% confidence level were obtained on the branching fractions of the Higgs boson decays to ϕγ and ργ of 4.8 × 10−4 and 8.8 × 10−4, respectively. The corresponding 95% confidence level upper limits for the Z boson decays are 0.9 × 10−6 and 25 × 10−6 for ϕγ and ργ, respectively.[Figure not available: see fulltext.]. © 2018, The Author(s).
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| 26. |
- Aaboud, M, et al.
(författare)
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Search for Higgs boson pair production in the bb¯ WW * decay mode at √s = 13 TeV with the ATLAS detector
- 2019
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Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2019:4
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Tidskriftsartikel (refereegranskat)abstract
- A search for Higgs boson pair production in the bb¯ WW * decay mode is performed in the bb¯ ℓνqq final state using 36.1 fb −1 of proton-proton collision data at a centre-of-mass energy of 13 TeV recorded with the ATLAS detector at the Large Hadron Collider. No evidence of events beyond the background expectation is found. Upper limits on the non-resonant pp → HH production cross section of 10 pb and on the resonant production cross section as a function of the HH invariant mass are obtained. Resonant production limits are set for scalar and spin-2 graviton hypotheses in the mass range 500 to 3000 GeV.[Figure not available: see fulltext.] © 2019, The Author(s).
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| 27. |
- Aad, G., et al.
(författare)
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Determination of the strong coupling constant from transverse energy-energy correlations in multijet events at √ s=13 TeV with the ATLAS detector
- 2023
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Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479. ; 2023:7
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Tidskriftsartikel (refereegranskat)abstract
- Measurements of transverse energy-energy correlations and their associated azimuthal asymmetries in multijet events are presented. The analysis is performed using a data sample corresponding to 139 fb-1 of proton-proton collisions at a centre-of-mass energy of root s = 13TeV, collected with the ATLAS detector at the Large Hadron Collider. The measurements are presented in bins of the scalar sum of the transverse momenta of the two leading jets and unfolded to particle level. They are then compared to next-to-next-to-leading-order perturbative QCD calculations for the first time, which feature a significant reduction in the theoretical uncertainties estimated using variations of the renormalisation and factorisation scales. The agreement between data and theory is good, thus providing a precision test of QCD at large momentum transfers Q. The strong coupling constant alpha(s) is extracted as a function of Q, showing a good agreement with the renormalisation group equation and with previous analyses. A simultaneous fit to all transverse energy-energy correlation distributions across different kinematic regions yields a value of alpha(s)( mZ) = 0.1175 +/- 0.0006 (exp.)(+0.0034) (-0.0017) (theo.), while the global fit to the asymmetry distributions yields alpha(s)(m(Z)) = 0.1185 +/- 0.0009 (exp.)(+0.0025)(-0.0012)(theo.).
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| 28. |
- Aad, G., et al.
(författare)
-
Inclusive-photon production and its dependence on photon isolation in pp collisions at √s=13 TeV using 139 fb-1 of ATLAS data
- 2023
-
Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479. ; 2023:7
-
Tidskriftsartikel (refereegranskat)abstract
- Measurements of differential cross sections are presented for inclusive isolated photon production in pp collisions at a centre-of-mass energy of 13TeV provided by the LHC and using 139 fb-1 of data recorded by the ATLAS experiment. The cross sections are measured as functions of the photon transverse energy in different regions of photon pseudorapidity. The photons are required to be isolated by means of a fixed-cone method with two different cone radii. The dependence of the inclusive-photon production on the photon isolation is investigated by measuring the fiducial cross sections as functions of the isolation-cone radius and the ratios of the differential cross sections with different radii in different regions of photon pseudorapidity. The results presented in this paper constitute an improvement with respect to those published by ATLAS earlier: the measurements are provided for different isolation radii and with a more granular segmentation in photon pseudorapidity that can be exploited in improving the determination of the proton parton distribution functions. These improvements provide a more in-depth test of the theoretical predictions. Next-to-leading-order QCD predictions from JETPHOX and SHERPA and next-to-next-to-leading-order QCD predictions from NNLOJET are compared to the measurements, using several parameterisations of the proton parton distribution functions. The measured cross sections are well described by the fixed-order QCD predictions within the experimental and theoretical uncertainties in most of the investigated phase-space region.
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| 29. |
- Aad, G, et al.
(författare)
-
Measurements of the Higgs boson inclusive and differential fiducial cross sections in the 4 ℓ decay channel at √s = 13 TeV
- 2020
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 80:10
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Tidskriftsartikel (refereegranskat)abstract
- Inclusive and differential fiducial cross sections of the Higgs boson are measured in the H→ ZZ∗→ 4 ℓ (ℓ= e, μ) decay channel. The results are based on proton−proton collision data produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector from 2015 to 2018, equivalent to an integrated luminosity of 139 fb - 1. The inclusive fiducial cross section for the H→ ZZ∗→ 4 ℓ process is measured to be σfid= 3.28 ± 0.32 fb, in agreement with the Standard Model prediction of σfid , SM= 3.41 ± 0.18 fb. Differential fiducial cross sections are measured for a variety of observables which are sensitive to the production and decay of the Higgs boson. All measurements are in agreement with the Standard Model predictions. The results are used to constrain anomalous Higgs boson interactions with Standard Model particles. © 2020, The Author(s).
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| 30. |
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| 31. |
- Alam, Assad, et al.
(författare)
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Look-Ahead Cruise Control for Heavy Duty Vehicle Platooning
- 2013
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Ingår i: Proceedings of the 16th International IEEE Annual Conference onIntelligent Transportation Systems (ITSC 2013). - : IEEE conference proceedings. - 9781479929146 ; , s. 928-935
-
Konferensbidrag (refereegranskat)abstract
- Vehicle platooning has become important for thevehicle industry. Yet conclusive results with respect to thefuel reduction possibilities of platooning remain unclear, inparticular when considering constraints imposed by the topography.The focus of this study is to establish whether itis more fuel-efficient to maintain or to split a platoon that isfacing steep uphill and downhill segments. Two commercialcontrollers, an adaptive cruise controller and a look-aheadcruise controller, are evaluated and alternative novel controlstrategies are proposed. The results show that an improvedfuel-efficiency can be obtained by maintaining the platoonthroughout a hill. Hence, a cooperative control strategy basedon preview information is presented, which initiates the changein velocity at a specific point in the road for all vehiclesrather than simultaneously changing the velocity to maintainthe spacing. A fuel reduction of up to 14% can be obtainedover a steep downhill segment and a more subtle benefit of0.7% improvement over an uphill segment with the proposedcontroller, compared to the combination of the commerciallyavailable cruise controller and adaptive cruise controller thatcould be used for platooning. The findings show that it isboth fuel-efficient and desirable in practice to consider previewinformation of the topography in the control strategy.
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| 32. |
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| 33. |
- Andersson, Tomas, et al.
(författare)
-
Photon energy influence on valence photoelectron spectra of silver clusters
- 2012
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Ingår i: Journal of Physics, Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 388:15, s. 152028-
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Tidskriftsartikel (refereegranskat)abstract
- Silver clusters in the size range of ∼102 constituent atoms have been studied using photoelectron spec-troscopy. The 5s and 4d valence bands have been probed with 40 and 60.5 eV photon energies. Differences in the valence band spectral features have been observed and are discussed in view of earlier results on copper clusters and in terms of differences in mean free path for electrons of different energies.
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| 34. |
- Antonsson, H, et al.
(författare)
-
VIBRATIONAL MOTION AND GEOMETRICAL STRUCTURE IN ADSORBED CO STUDIED BY CORE LEVEL PHOTOELECTRON-SPECTROSCOPY
- 1990
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Ingår i: Journal of Electron Spectroscopy and Related Phenomena. - 0368-2048. ; 54, s. 601-613
-
Tidskriftsartikel (refereegranskat)abstract
- High resolution core level spectra from CO adsorbed on clean and hydrogen precovered Ni(100) and CO adsorbed on Cu(100) are presented. The core level binding energy is shown to be sensitive to the adsorption site. Cluster calculations reproduce the general trend of the binding energy shifts between the on top and hollow sites of CO/Ni(100). In the coadsorption system CO/H/Ni(100) three different adsorption sites have been observed with a maximum binding energy shift of 2.6 eV for the Ols level. The temperature dependence of the Cls and Ols line profiles in CO/Ni(100) has been carefully investigated. The temperature dependent broadening is due to thermal excitations of frustrated translations parallel to the surface. The spectra from CO on Cu(100) show no temperature dependence below 200K.
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| 35. |
- Bai, Ting, et al.
(författare)
-
A Pricing Rule for Third-Party Platoon Coordination Service Provider
- 2022
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Ingår i: ASCC 2022 - 2022 13th Asian Control Conference, Proceedings. - : Institute of Electrical and Electronics Engineers (IEEE). ; , s. 2344-2349
-
Konferensbidrag (refereegranskat)abstract
- We model a platooning system including trucks and a third-party service provider that performs platoon coordination, distributes the platooning profit within platoons, and charges the trucks in exchange for its services. This paper studies one class of pricing rules, where the third-party service provider keeps part of the platooning profit each time a platoon is formed. Furthermore, we propose a platoon coordination solution based on distributed model predictive control in which the pricing rule is integrated. To evaluate the effect of the pricing on the platooning system, we perform a simulation over the Swedish road network. The simulation shows that the platooning rate and profit highly depend on the pricing. This suggests that pricing needs to be set carefully to obtain a satisfactory platooning system in the future.
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| 36. |
- Bai, Ting, et al.
(författare)
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Approximate Dynamic Programming for Platoon Coordination under Hours-of-Service Regulations
- 2022
-
Ingår i: 2022 IEEE 61ST CONFERENCE ON DECISION AND CONTROL (CDC). - : Institute of Electrical and Electronics Engineers (IEEE). ; , s. 7663-7669
-
Konferensbidrag (refereegranskat)abstract
- Truck drivers are required to stop and rest with a certain regularity according to the driving and rest time regulations, also called Hours-of-Service (HoS) regulations. This paper studies the problem of optimally forming platoons when considering realistic HoS regulations. In our problem, trucks have fixed routes in a transportation network and can wait at hubs along their routes to form platoons with others while fulfilling the driving and rest time constraints. We propose a distributed decision-making scheme where each truck controls its waiting times at hubs based on the predicted schedules of others. The decoupling of trucks' decision-makings contributes to an approximate dynamic programming approach for platoon coordination under HoS regulations. Finally, we perform a simulation over the Swedish road network with one thousand trucks to evaluate the achieved platooning benefits under the HoS regulations in the European Union (EU). The simulation results show that, on average, trucks drive in platoons for 37 % of their routes if each truck is allowed to be delayed for 5 % of its total travel time. If trucks are not allowed to be delayed, they drive in platoons for 12 % of their routes.
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| 37. |
- Bai, Ting, et al.
(författare)
-
Event-Triggered Distributed Model Predictive Control for Platoon Coordination at Hubs in a Transport System
- 2021
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Ingår i: 2021 60TH IEEE CONFERENCE ON DECISION AND CONTROL (CDC). - : Institute of Electrical and Electronics Engineers (IEEE). ; , s. 1198-1204
-
Konferensbidrag (refereegranskat)abstract
- This paper considers the problem of hub-based platoon coordination for a large-scale transport system, where trucks have individual utility functions to optimize. An event-triggered distributed model predictive control method is proposed to solve the optimal scheduling of waiting times at hubs for individual trucks. In this distributed framework, trucks are allowed to decide their waiting times independently and only limited information is shared between trucks. Both the predicted reward gained from platooning and the predicted cost for waiting at hubs are included in each truck's utility function. The performance of the coordination method is demonstrated in a simulation with one hundred trucks over the Swedish road network.
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| 38. |
- Bai, Ting, et al.
(författare)
-
Large-Scale Multi-Fleet Platoon Coordination : A Dynamic Programming Approach
- 2023
-
Ingår i: IEEE transactions on intelligent transportation systems (Print). - : Institute of Electrical and Electronics Engineers (IEEE). - 1524-9050 .- 1558-0016. ; 24:12, s. 14427-14442
-
Tidskriftsartikel (refereegranskat)abstract
- Truck platooning is a promising technology that enables trucks to travel in formations with small inter-vehicle distances for improved aerodynamics and fuel economy. The real-world transportation system includes a vast number of trucks owned by different fleet owners, for example, carriers. To fully exploit the benefits of platooning, efficient dispatching strategies that facilitate the platoon formations across fleets are required. This paper presents a distributed framework for addressing multi-fleet platoon coordination in large transportation networks, where each truck has a fixed route and aims to maximize its own fleet's platooning profit by scheduling its waiting times at hubs. The waiting time scheduling problem of individual trucks is formulated as a distributed optimal control problem with continuous decision space and a reward function that takes non-zero values only at discrete points. By suitably discretizing the decision and state spaces, we show that the problem can be solved exactly by dynamic programming, without loss of optimality. Finally, a realistic simulation study is conducted over the Swedish road network with 5,000 trucks to evaluate the profit and efficiency of the approach. The simulation study shows that, compared to single-fleet platooning, multi-fleet platooning provided by our method achieves around 15 times higher monetary profit and increases the CO2 emission reductions from 0.4% to 5.5%. In addition, it shows that the developed approach can be carried out in real-time and thus is suitable for platoon coordination in large transportation systems.
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| 39. |
- Bai, Ting, et al.
(författare)
-
Rollout-Based Charging Strategy for Electric Trucks With Hours-of-Service Regulations
- 2023
-
Ingår i: IEEE Control Systems Letters. - : Institute of Electrical and Electronics Engineers (IEEE). - 2475-1456. ; 7, s. 2167-2172
-
Tidskriftsartikel (refereegranskat)abstract
- Freight drivers of electric trucks need to design charging strategies for where and how long to recharge the truck in order to complete delivery missions on time. Moreover, the charging strategies should be aligned with drivers' driving and rest time regulations, known as hours-of-service (HoS) regulations. This letter studies the optimal charging problems of electric trucks with delivery deadlines under HoS constraints. We assume that a collection of charging and rest stations is given along a pre-planned route with known detours and that the problem data are deterministic. The goal is to minimize the total cost associated with the charging and rest decisions during the entire trip. This problem is formulated as a mixed integer program with bilinear constraints, resulting in a high computational load when applying exact solution approaches. To obtain real-time solutions, we develop a rollout-based approximate scheme, which scales linearly with the number of stations while offering solid performance guarantees. We perform simulation studies over the Swedish road network based on realistic truck data. The results show that our rollout-based approach provides near-optimal solutions to the problem in various conditions while cutting the computational time drastically.
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| 40. |
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| 41. |
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| 42. |
- Bergenfelz, Anders, et al.
(författare)
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Complications to thyroid surgery : results as reported in a database from a multicenter audit comprising 3,660 patients
- 2008
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Ingår i: Langenbeck's archives of surgery (Print). - : Springer. - 1435-2443 .- 1435-2451. ; 393:5, s. 667-673
-
Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIM: During recent years, more radical surgery for thyroid disease, i.e., total instead of subtotal resection, has been evident. Results following this strategy on national levels are scarce.MATERIALS AND METHODS: From 2004 to 2006, 26 Scandinavian Departments registered 3,660 thyroid operations in a database. Risk factors for complications were analyzed with multiple logistic regression.RESULTS: After thyroidectomy, re-bleeding occurred in 2.1% and was associated with older age (OR 1.04; p < 0.0001) and male gender (OR 1.90; p = 0.014). Postoperative infection occurred in 1.6% and associated with lymph node operation (OR 8.18; p < 0.0001). Postoperative unilateral paresis of the recurrent laryngeal nerve was diagnosed 3.9% and bilateral paresis in 0.2%. Unilateral paresis was associated with older age, intrathoracic goiter, thyreotoxicosis, and if routine laryngoscopy was practiced (OR 1.92; p = 0.0002). After 6 months, the incidence of nerve paresis was 0.97%. After bilateral thyroid surgery (n = 1,648), hypocalcaemia treated with vitamin D analogue occurred in 9.9% of the patients at the first follow-up and in 4.4% after 6 months.CONCLUSION: Complications to thyroid surgery are not uncommon. The high frequency of hypocalcaemia treated with vitamin D after 6 months is a cause of concern.
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| 43. |
- Bergh, Ingrid H. E., et al.
(författare)
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Assessment and documentation of women's labour pain : A cross-sectional study in Swedish delivery wards
- 2015
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Ingår i: Women and Birth. - : Elsevier. - 1871-5192 .- 1878-1799. ; 28:2, s. E14-E18
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Tidskriftsartikel (refereegranskat)abstract
- Background: A woman's pain during labour plays a dominant role in childbirth. The midwife's role is to assess the degree of pain experienced during labour. When professionals respond to labour pain with acknowledgement and understanding, the woman's sense of control and empowerment is increased, which could contribute to a positive experience of childbirth. The aim of this study is to describe how labour pain in Swedish delivery wards is assessed and documented. Methods: This quantitative descriptive study was designed as a national survey performed through telephone interviews with the representatives of 34 delivery wards in Sweden. Results and conclusion: The majority of the participating delivery wards assessed and documented women's labour pain, but in an unstructured manner. The wards differed in how the assessments and documentation were performed. In addition, almost all the delivery wards that participated in the survey lacked guidelines for the assessment and documentation of the degree of pain during labour. The findings also showed that the issue of labour pain was sometimes discussed in the delivery wards, but not in a structured or consistent way. (C) 2015 Australian College of Midwives. Published by Elsevier Australia (a division of Reed International Books Australia Pty Ltd). All rights reserved.
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| 44. |
- Bergh, Ingrid H. E., et al.
(författare)
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Midwifery students attribute different quantitative meanings to "hurt", "ache" and "pain" : A cross-sectional survey
- 2013
-
Ingår i: Women and Birth. - : Elsevier. - 1871-5192 .- 1878-1799. ; 26:2, s. 143-146
-
Tidskriftsartikel (refereegranskat)abstract
- Background: Assessment of women's labor pain is seldom acknowledged in clinical practice or research. The words "aching" and "hurting" are frequently used by women to describe childbirth pain. The aim of this study was to determine the quantitative meanings midwifery students attribute to the terms "hurt", "ache" and "pain". Data was collected by self-administered questionnaire from students at seven Swedish midwifery programs. A total of 230 filled out and returned a completed questionnaire requesting them to rate, on a visual analog scale, the intensity of "hurt", "ache" or "pain" in the back, as reported by a fictitious parturient. Results: The midwifery students attributed, with substantial individual variation, different quantitative meanings to the studied pain descriptors. Conclusions: To be able to communicate about pain with a woman in labor, it is essential that the midwife be familiar with the value of different words and what they mean to her as this may affect her assessment when the woman describes her pain. © 2012.
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| 45. |
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| 46. |
- Boldemann, C., et al.
(författare)
-
Preschool outdoor play environment may combine promotion of children's physical activity and sun protection. Further evidence from Southern Sweden and North Carolina
- 2011
-
Ingår i: Science and Sports. - : Elsevier BV. - 0765-1597. ; 26:2, s. 72-82
-
Konferensbidrag (refereegranskat)abstract
- Objective. - To study the impact of preschool outdoor environments on children's physical activity and solar ultraviolet (UV) exposure at different latitudes and countries. Methods. Outdoor environments of 11 preschools (two in Raleigh NC, USA, Lat.36 degrees N, nine in Malmo, Sweden, Lat.55 degrees N) were scored (OPEC) regarding space, vegetation, hilly terrain and level of integration between open spaces, vegetation and play structures. Free sky (%) was determined by imaging. Physical activity was measured by pedometers and solar UV-exposure by polysulphone dosimeters during 5 days in spring 2009, and individual background data gathered by questionnaires and anthropometric measurements. Global UV radiation was measured and available individual UV radiation (%) computed. Results. - In Malmo, mean step count/minute was 21.2 in preschools with high-scored environment vs. 17.6 in low-scored environments, and UV-exposure lower, 26% vs. 43% of available UV during outdoor stay. In Raleigh, step count/minute was 12.3 and UV-exposure of available UV 27% during outdoor stay. Conclusions. - Step count/minute was lower in Raleigh than in Malmo, but in Malmo children at low-scored environments ran a higher risk of sunburn than in Raleigh. Trees and shrubbery integrated in children's playscape trigger both physical activity and sun-protective behaviour in Sweden, and previous measurements in Stockholm were confirmed. Such outdoor environment should be recommended, but the role of season and climate needs to be further explored. (C) 2011 Elsevier Masson SAS. All rights reserved.
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| 47. |
- Burman, Jörgen, et al.
(författare)
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Development of a blade geometry definition with implicit design variables
- 2000
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Ingår i: AIAA Paper 00-671. - : American Institute of Aeronautics and Astronautics, AIAA.
-
Konferensbidrag (refereegranskat)abstract
- This paper presents a method to create 3-dimensional blade geometries defined in terms of stacked profiles where each profile is described by four NURBS curves. The NURBS representations of the profiles are attractive since they can be exchanged with CAD/CAM systems and grid generators. The blade profiles are defined in terms of traditional design variables, e.g. maximum thickness and camber. A numerical optimisation loop is then used to adjust the basic parameters of the NURBS curves until the requested values of the traditional design variables are obtained. Normally the number of traditional design variables is less than the number of NURBS parametersI.t has therefore been necessaryt o define additional constraints that make the shape corresponding to a given set of traditional design variables unique.
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| 48. |
- Bäckström, Caroline A., et al.
(författare)
-
"It's like a puzzle" : Pregnant women's perceptions of professional support in midwifery care
- 2016
-
Ingår i: Women and Birth. - : Elsevier. - 1871-5192 .- 1878-1799. ; 29:6, s. e110-e118
-
Tidskriftsartikel (refereegranskat)abstract
- ProblemPregnant women are not always satisfied with the professional support they receive during their midwifery care. More knowledge is needed to understand what professional support pregnant women need for childbirth and parenting.BackgroundChildbearing and the transition to becoming a parent is a sensitive period in one's life during which one should have the opportunity to receive professional support. Professional support does not always correspond to pregnant women's needs. To understand pregnant women's needs for professional support within midwifery care, it is crucial to further illuminate women's experiences of this support.AimTo explore pregnant women's perceptions of professional support in midwifery care.MethodsA qualitative study using semi-structured interviews. Fifteen women were interviewed during gestational weeks 36–38. Data was analysed using phenomenography.FindingsThe women perceived professional support in midwifery care to be reassuring and emotional, to consist of reliable information, and to be mediated with pedagogical creativity. The professional support facilitated new social contacts, partner involvement and contributed to mental preparedness. The findings of the study were presented in six categories and the category Professional support contributes to mental preparedness was influenced by the five other categories.ConclusionPregnant women prepare for childbirth and parenting by using several different types of professional support in midwifery care: a strategy that could be described as piecing together a puzzle. When the women put the puzzle together, each type of professional support works as a valuable piece in the whole puzzle. Through this, professional support could contribute to women's mental preparedness for childbirth and parenting.
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| 49. |
- Chen, Xiao, et al.
(författare)
-
Safe Intersection Coordination with Mixed Traffic : From Estimation to Control
- 2023
-
Konferensbidrag (refereegranskat)abstract
- In this paper, we propose an integrated framework for safe intersection coordination of connected and automated vehicles (CAVs) in mixed traffic. An intelligent intersection is introduced as a central node to orchestrate state data sharing among connected agents and enable CAV to acknowledge the presence of human-driven vehicles (HDVs) beyond the line of sight of onboard sensors. Since state data shared between agents might be uncertain or delayed, we design the intelligent intersection to safely compensate for these uncertainties and delays using robust set estimation and forward reachability analysis. When the intersection receives state data from an agent, it first generates a zonotope to capture the possible measurement noise in the state estimate. Then, to compensate for communication and processing delays, it uses forward reachability analysis to enlarge the set to capture all the possible states the agent could have occupied throughout the delays. Finally, using the resulting set as the initial condition, a distributed model predictive control onboard the CAV will plan an invariant safe motion by considering the worst-case behavior of human drivers. As a result, the vehicle is guaranteed to be safe while driving through the intersection. A prototype of our proposed framework is implemented using.
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| 50. |
- Cook, Jackie, et al.
(författare)
-
Loop-mediated isothermal amplification (LAMP) for point-of-care detection of asymptomatic low-density malaria parasite carriers in Zanzibar
- 2015
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Ingår i: Malaria Journal. - : Springer Science and Business Media LLC. - 1475-2875. ; 14, s. 43-
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Tidskriftsartikel (refereegranskat)abstract
- Background: Asymptomatic, low parasite density malaria infections are difficult to detect with currently available point-of-care diagnostics. This study piloted a loop-mediated isothermal amplification (LAMP) kit for field-friendly, high-throughput detection of asymptomatic malaria infections during mass screening and treatment (MSAT) in Zanzibar, a malaria pre-elimination setting. Methods: Screening took place in three known hotspot areas prior to the short rains in November. Finger-prick blood was taken for screening by rapid diagnostic test (RDT) and LAMP and collected on filter paper for subsequent polymerase chain reaction (PCR) analyses. LAMP results were compared to RDT and to PCR using McNemar's test. Results: Approximately 1,000 people were screened. RDT detected ten infections (1.0% (95% CI 0.3-1.6)) whilst both LAMP and PCR detected 18 (1.8% (95% CI 0.9-2.6)) infections. However, PCR identified three infections that LAMP did not detect and vice versa. LAMP testing was easy to scale-up in field conditions requiring minimal training and equipment, with results ready one to three hours after screening. Conclusions: Despite lower than expected prevalence, LAMP detected a higher number of infections than the currently used diagnostic, RDT. LAMP is a field-friendly, sensitive diagnostic test that could be useful for MSAT malaria campaigns which require quick results to enable prompt treatment.
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