| 1. |
|
|
| 2. |
- Backofen, Rolf, et al.
(författare)
-
Usage of bioinformatics tools and identification of information sources
- 2005
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Bioinformatics is an important application area for semantic web technologies as much of the data is online and accessible in XML format, as some sites already support web services, and as ontologies are widely used to annotate data. In this deliverable, we give a survey over 18 of the most important bioinformatics resources and discuss their availability and accessibility, which are two of the main criteria for these resources to act as bases for later demonstrators.
|
|
| 3. |
|
|
| 4. |
- Bayer, Daniel, et al.
(författare)
-
Dynamic Runtime Environments for Grid Computing
- 2008
-
Ingår i: CGW'07 Proceedings. - 9788391514191 ; , s. 155-162
-
Konferensbidrag (refereegranskat)abstract
- In a grid computing context the execution of jobs on remote machines of collaborating institutes often requires the provisioning of more than mere CPU time. Besides libraries and utilities distributed with the operating system in question, further software may be required by the jobs and in such cases need to be installed prior to the job's execution. In grid computing this problem is aggravated by decreased personal contacts among collaborators. Currently, Virtual Organisations of existing production grids typically agree on a set of runtime environments that participating sites install manually. The challenge is to automate this process, thus easing the burden of the site's maintainers and allowing grid-wide software updates with immediate eject. This paper presents an RDF based schema for the description of runtime environments and the implementation of a service for their automated and dynamic installation.
|
|
| 5. |
- Connolly, David, et al.
(författare)
-
Heat Roadmap Europe : Combining district heating with heat savings to decarbonise the EU energy system
- 2014
-
Ingår i: Energy Policy. - London : Elsevier. - 0301-4215 .- 1873-6777. ; 65, s. 475-489
-
Tidskriftsartikel (refereegranskat)abstract
- Six different strategies have recently been proposed for the European Union (EU) energy system in the European Commission’s report, Energy Roadmap 2050. The objective for these strategies is to identify how the EU can reach its target of an 80% reduction in annual greenhouse gas emissions in 2050 compared to 1990 levels. None of these scenarios involve the large-scale implementation of district heating, but instead they focus on the electrification of the heating sector (primarily using heat pumps) and/or the large-scale implementation of electricity and heat savings. In this paper, the potential for district heating in the EU between now and 2050 is identified, based on extensive and detailed mapping of the EU heat demand and various supply options. Subsequently, a new ‘district heating plus heat savings’ scenario is technically and economically assessed from an energy systems perspective. The results indicate that with district heating, the EU energy system will be able to achieve the same reductions in primary energy supply and carbon dioxide emissions as the existing alternatives proposed. However, with district heating, these goals can be achieved at a lower cost, with heating and cooling costs reduced by approximately 15%. © 2013 Elsevier Ltd.
|
|
| 6. |
- Connolly, David, et al.
(författare)
-
Heat Roadmap Europe 2050 : Second Pre-study for the EU27
- 2013
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Many strategies have already been proposed for the decarbonisation of the EU energy system by the year 2050. These typically focus on the expansion of renewable energy in the electricity sector and subsequently, electrifying both the heat and transport sectors as much as possible. In these strategies, the role of district heating has never been fully explored system, nor have the benefits of district heating been quantified at the EU level. This study combines the mapping of local heat demands and local heat supplies across the EU27. Using this local knowledge, new district heating potentials are identified and then, the EU27 energy system is modelled to investigate the impact of district heating. The results indicate that a combination of heat savings, district heating in urban areas, and individual heat pumps in rural areas will enable the EU27 to reach its greenhouse gas emission targets by 2050, but at a cheaper price than a scenario which focuses primarily on the implementation of heat savings.
|
|
| 7. |
- Connolly, David, et al.
(författare)
-
Heat Roadmap Europe 2050 : First Pre-study for the EU27
- 2012
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This pre-study presents the findings concerning a considerable outlined expansion of the district heating sector within the current EU27 member states until 2050. Heat deliveries are presumed to grow by a factor of 2.1 until 2030 and by a factor of 3.3 until 2050.The current energy policy context is that the latest energy communication from the European Commission (Energy Roadmap 2050) contains only a very modest growth in the future for district heating systems and additional industrial heat use from industrial CHP plants. A small increase is foreseen for industrial demands, while heat deliveries to the residential and service sectors are expected to decrease. In total, the heat delivered is expected to increase by less than one per cent per year, giving a total increase of 20% until 2030 and of 40% until 2050.In this prestudy, more ambitious growth rates are assessed for district heating in the EU27 between 2010 and 2050. The chosen methodology in this pre-study contains a combination of hour-by-hour energy modelling of the EU27 energy system and mapping of local conditions, which is essential for district heating analysis. However, the link between these two actions has not been fully utilised in this pre-study due to the limited working time available: The mapping action has only indicated the input to the energy modelling action.
|
|
| 8. |
- Connolly, David, et al.
(författare)
-
The role of district heating in decarbonising the EU energy system and a comparison with existing strategies
- 2013
-
Ingår i: Book of Abstracts.
-
Konferensbidrag (refereegranskat)abstract
- Many strategies have already been proposed for the decarbonisation of the EU energy system by the year 2050. These typically focus on the expansion of renewable energy in the electricity sector and subsequently, electrifying both the heat and transport sectors as much as possible. In these strategies, the role of district heating has never been fully explored system, nor have the benefits of district heating been quantified at the EU level. This study combines the mapping of local heat demands and local heat supplies across the EU27. Using this local knowledge, new district heating potentials are identified and then, the EU27 energy system is modelled to investigate the impact of district heating. The results indicate that a combination of heat savings, district heating in urban areas, and individual heat pumps in rural areas will enable the EU27 to reach its greenhouse gas emissions targets by 2050, but at a cheaper price than a scenario which focuses primarily on the implementation of heat savings.
|
|
| 9. |
- Hemmingsen, Jette Gjerke, et al.
(författare)
-
Controlled exposure to diesel exhaust and traffic noise - Effects on oxidative stress and activation in mononuclear blood cells.
- 2015
-
Ingår i: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. - : Elsevier BV. - 1879-2871 .- 0027-5107. ; 775, s. 66-71
-
Tidskriftsartikel (refereegranskat)abstract
- Particulate air pollution increases risk of cancer and cardiopulmonary disease, partly through oxidative stress. Traffic-related noise increases risk of cardiovascular disease and may cause oxidative stress. In this controlled random sequence study, 18 healthy subjects were exposed for 3h to diesel exhaust (DE) at 276μg/m(3) from a passenger car or filtered air, with co-exposure to traffic noise at 48 or 75dB(A). Gene expression markers of inflammation, (interleukin-8 and tumor necrosis factor), oxidative stress (heme oxygenase (decycling-1)) and DNA repair (8-oxoguanine DNA glycosylase (OGG1)) were unaltered in peripheral blood mononuclear cells (PBMCs). No significant differences in DNA damage levels, measured by the comet assay, were observed after DE exposure, whereas exposure to high noise levels was associated with significantly increased levels of hOGG1-sensitive sites in PBMCs. Urinary levels of 8-oxo-7,8-dihydro-2'-deoxyguanosine were unaltered. In auxiliary ex vivo experiments whole blood was incubated with particles from the exposure chamber for 3h without effects on DNA damage in PBMCs or intracellular reactive oxygen species production and expression of CD11b and CD62L adhesion molecules in leukocyte subtypes.
|
|
| 10. |
|
|
| 11. |
|
|
| 12. |
- Mafael, Alexander, et al.
(författare)
-
Please Do Not Buy Our Brand—How Consumers Respond to Green-Demarketing Messages
- 2023. - 1
-
Ingår i: Forum Markenforschung 2021. - Wiesbaden : Springer Fachmedien Wiesbaden. - 3658395672 - 9783658395674 ; , s. 105-118
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- In response to the negative impact of consumption on sustainability, some brands have begun to practice green demarketing (GDM)—an extension of demarketing that discourages demand for products for the sake of the environment. This study examines how consumers process GMD messages and tests the impact of GMD messages on brand attitudes. We propose two opposing mechanisms that affect consumers’ attitudes towards a GDM ad message. While GDM ad messages might profit from their sustainability focus, attitudes toward GDM ad messages are also likely to be compromised by low processing fluency and increased skepticism. Results of an online experiment with fictitious ad messages show that attitudes toward sustainable ad messages are significantly higher than attitudes toward a non-sustainable ad message. In addition, our results reveal a significant negative, indirect effect of a GDM message on attitudes toward the ad that is serially mediated by processing fluency and skepticism. Results of this research are important for brand managers, since we demonstrate a positive effect of attitudes toward the ad on attitudes toward the brand.
|
|
| 13. |
- Möller, Bernd, et al.
(författare)
-
Online web map application and first set of map layers : D5.3
- 2020
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The present report describes in overview how the Pan-European Thermal Atlas (Peta) was developed further into a spatial information system for the geography of energy efficiency potentials in the building, transport, and industry sectors, as well as the associated infrastructures. The resulting online atlas allows for visualisation of energy efficiency potentials between sectors in a common mapping environment. The additions and updates to the Pan-European Thermal Atlas (originally developed for the Heat Roadmap Europe projects) into a cross-sectoral mapping platform necessitated updates to the data layers, the layout, and the documentation. Layers with heat demand data from the building sector were updated, now to include all of the EU28, while a new map layer depicting the possible reduction of specific heat demand in buildings, as a measure of the current energy efficiency potential in this sector, is currently under development but not yet part of this deliverable (see sections 2.2 and 2.4 for further information). This new layer will be added to Peta 5.0.1 as soon as possible. For the transport and industry sectors, current year energy efficiency potentials were possible to assess and map in the present context. In the transport sector, findings were translated into geographical distributions of potentials and materialise as a set of geospatial map layers. In the industrial sector, energy efficiency in industry has been quantified partly for on-site energy savings, partly for off-site excess heat recovery in district heating systems, and the results have been turned into geographical representations in the form of energy efficiency surfaces. The Peta online mapping system is prepared to include further layers from future deliverables, such as thermal, gas, and electrical grids. Finally, the mapping of future scenarios will be made available using the present online mapping environment.
|
|
| 14. |
- Möller, Bernd, et al.
(författare)
-
Spatial models and spatial analytics results : D5.7
- 2022
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The present report accounts for the spatial models of energy efficiency and the geospatial analysis carried out to quantify and locate energy efficiency potentials across sectors. In the building sector, future heat demands on national scales are being distributed using the age class of built-up areas and innovative models of future population distribution. District heat distribution capital costs combined with heat demand densities allow for the assessment of economic potentials of future district heating. Efficiency potentials in the transport and industrial sectors have been associated to locations, and transmission infrastructures have been mapped. Combining all these aspects, spatial analytics help understanding the opportunities and constraints that arise from the geography of energy systems. Energy efficiency in the three sectors has been mapped at different scales. Cost curves for district heating have been prepared for member states. For use in energy systems analysis, a matrix has been developed that relates energy efficiency in buildings and district heating potentials. Areas of interest for the conversion of natural gas to district heating have been mapped, combining present gas use with infrastructural aspects. Local potentials of district heating have been quantified for almost 150,000 settlements, and potential heat sources from industrial and wastewater treatment plants as well as locally available renewable energy sources have been allocated to potential district heating areas. Finally, to visualise and compare energy efficiency across sectors, technologies, and countries, the sEEnergies Index shows local potentials for improving energy efficiency and utilising synergies in all settlements of the EU27 plus the UK. In conclusion, the report documents how dissemination can be facilitated using the online geospatial information and mapping applications prepared in the sEEnergies Project.
|
|
| 15. |
|
|
| 16. |
|
|
| 17. |
- Möller, Steffen, et al.
(författare)
-
Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids
- 2020
-
Ingår i: Aging. - : Impact Journals LLC. - 1945-4589. ; 12:13, s. 12534-12581
-
Forskningsöversikt (refereegranskat)abstract
- The molecular basis of aging and of aging-associated diseases is being unraveled at an increasing pace. An extended healthspan, and not merely an extension of lifespan, has become the aim of medical practice. Here, we define health based on the absence of diseases and dysfunctions. Based on an extensive review of the literature, in particular for humans and C. elegans, we compile a list of features of health and of the genes associated with them. These genes may or may not be associated with survival/lifespan. In turn, survival/lifespan genes that are not known to be directly associated with health are not considered. Clusters of these genes based on molecular interaction data give rise to maps of healthspan pathways for humans and for C. elegans. Overlaying healthspan-related gene expression data onto the healthspan pathway maps, we observe the downregulation of (pro-inflammatory) Notch signaling in humans and of proliferation in C. elegans. We identify transcription, proliferation/biosynthesis and lipids as a common theme on the annotation level, and proliferation-related kinases on the gene/protein level. Our literature-based data corpus, including visualization, should be seen as a pilot investigation of the molecular underpinnings of health in two different species.
|
|
| 18. |
- Nieminen, Markku S, et al.
(författare)
-
The role of levosimendan in acute heart failure complicating acute coronary syndrome: A review and expert consensus opinion.
- 2016
-
Ingår i: International journal of cardiology. - : Elsevier BV. - 1874-1754 .- 0167-5273. ; 218, s. 150-157
-
Tidskriftsartikel (refereegranskat)abstract
- Acute heart failure and/or cardiogenic shock are frequently triggered by ischemic coronary events. Yet, there is a paucity of randomized data on the management of patients with heart failure complicating acute coronary syndrome, as acute coronary syndrome and cardiogenic shock have frequently been defined as exclusion criteria in trials and registries. As a consequence, guideline recommendations are mostly driven by observational studies, even though these patients have a particularly poor prognosis compared to heart failure patients without signs of coronary artery disease. In acute heart failure, and especially in cardiogenic shock related to ischemic conditions, vasopressors and inotropes are used. However, both pathophysiological considerations and available clinical data suggest that these treatments may have disadvantageous effects. The inodilator levosimendan offers potential benefits due to a range of distinct effects including positive inotropy, restoration of ventriculo-arterial coupling, increases in tissue perfusion, and anti-stunning and anti-inflammatory effects. In clinical trials levosimendan improves symptoms, cardiac function, hemodynamics, and end-organ function. Adverse effects are generally less common than with other inotropic and vasoactive therapies, with the notable exception of hypotension. The decision to use levosimendan, in terms of timing and dosing, is influenced by the presence of pulmonary congestion, and blood pressure measurements. Levosimendan should be preferred over adrenergic inotropes as a first line therapy for all ACS-AHF patients who are under beta-blockade and/or when urinary output is insufficient after diuretics. Levosimendan can be used alone or in combination with other inotropic or vasopressor agents, but requires monitoring due to the risk of hypotension.
|
|
| 19. |
- Wiechers, Eva, et al.
(författare)
-
Geographic layers that illustrate future energy efficiency potentials: Second set of map layers (future years scenarios for 2030 and 2050) : D5.5
- 2022
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The Pan-European Thermal Atlas Peta is an online visualization tool for spatial data. Version 5.1 was launched in 2020 with a first set of layers for the EU27+UK, which related to energy demands in the base year and first, intermediate project results regarding energy efficiency potentials. With the update to version 5.2, Peta was complemented with layers based on the scenarios studied in different sEEnergies tasks, completed after the launch of Peta 5.1. As a result, Peta 5.2 shows energy demand and energy efficiency data for residential and service sector buildings as well as for industry and transport for different scenarios, focusing on the status-quo and the scenario year 2050, while also containing 2030 data.Throughout the Heat Roadmap Europe projects, Peta has been developed as an information system for the heat sector. Its main content related to district heating grid investment costs, district heating area demarcations and supply options. The current version 5.2 features new layers that include future heat demands and district heating development costs for distribution and service pipe investment costs, as well as energy efficiency potentials of the industry and transport sectors.In a new layer group Peta 5.2 presents the results of spatial analyses, for example the allocation of excess heat to urban areas as well as an index that combines energy efficiency potentials across sectors and technologies.Peta 5.2 can be accessed via the following URL:https://tinyurl.com/peta5seenergies, while the geospatial data can be accessed through thesEEnergies Open Data Hub: https://s-eenergies-open-data-euf.hub.arcgis.com/. Furthermore, Story Maps add an additional dimension to the dissemination of project results (accessible here: https://tinyurl.com/sEEnergiesStorymaps).
|
|
