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- Ramoniene, G., et al.
(författare)
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Maternal obesity and obstetric outcomes in a tertiary referral center
- 2017
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Ingår i: Medicina-Lithuania. - : MDPI AG. - 1010-660X. ; 53:2, s. 109-113
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Tidskriftsartikel (refereegranskat)abstract
- Background and aim: Obese women are at an increased risk of various adverse pregnancy outcomes. The aim of our study was to evaluate the impact of obesity on maternal and neonatal outcomes in a tertiary referral center and to compare obstetric outcomes by the level of maternal obesity. Materials and methods: A cohort study included 3247 women with singleton gestations who gave birth at the Department of Obstetrics and Gynecology, Lithuanian University of Health Sciences, in 2010. Pregnancy complications and neonatal outcomes were identified using the hospital Birth Registry database in normal weight (body mass index [BMI] 18.5-24.9 kg/m(2), n = 3107) and prepregnancy obese (BMI >= 30 kg/m(2), n = 140) women. Pregnancy outcomes were compared according to the level of obesity (BMI 30-34.9 kg/m(2), n = 94 and BMI kg/m(2), n = 46). Results: Obese women were significantly more likely to have gestational hypertension (OR = 8.59; 95% CI, 5.23-14.14; P < 0.0001), preeclampsia (OR = 2.06; 95% CI, 1.14-3.73; P < 0.0001), gestational diabetes (OR = 5.56; 95% CI, 3.66-8.49; P < 0.0001), dystocia (OR = 2.14; 95% CI, 1.36-3.38; P < 0.0001), induced labor (OR = 2.64; 95% CI, 1.83-3.80; P < 0.0001), failed induction of labor (OR = 18.06; 95% CI, 8.85-36.84; P < 0.0001), cesarean delivery (OR = 1.76; 95% CI, 1.25-2.49; P = 0.001), large-for-gestational-age newborns (OR = 3.68; 95% CI, 2.51-5.39; P < 0.0001). Significantly increased risk of gestational diabetes, preeclampsia, dystocia and newborns with Apgar score <= 7 after 5 min was only observed in women with BMI >= 35 kg/m(2). Conclusions: Maternal obesity is significantly associated with an increased risk of gestational hypertension, preeclampsia, gestational diabetes, dystocia, labor induction, failed induction of labor, large-for-gestational-age newborns and cesarean delivery. (C) 2017 The Lithuanian University of Health Sciences.
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| 2. |
- Gaurilcikas, A., et al.
(författare)
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Early-stage cervical cancer: agreement between ultrasound and histopathological findings with regard to tumor size and extent of local disease
- 2011
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Ingår i: Ultrasound in Obstetrics & Gynecology. - : Wiley. - 1469-0705 .- 0960-7692. ; 38:6, s. 707-715
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Tidskriftsartikel (refereegranskat)abstract
- Objectives To determine the agreement between ultrasound and histological examination of the cervix in patients with early stage cervical cancer with regard to tumor size and local extent of the disease. Methods Eighteen patients with histologically proven cervical cancer Stage IB1-IIA according to traditional clinical staging (FIGO 1988) who were scheduled for radical surgery underwent a standardized transvaginal ultrasound examination. The maximum tumor length, anteroposterior tumor diameter, tumor width, tumor area, depth of cervical stroma invasion, and the minimal thickness of tumor-free cervical stroma on sagittal and transverse planes through the cervix were measured, and the local extent of the disease within the parametria and vagina were evaluated. The surgical specimens were examined using a specifically devised method of histopathological examination. The results of the ultrasound and histopathological examinations were compared. Results Limits of agreement were wide and the intra-class correlation coefficient (ICC) was low (0.51-0.58) for three of the four measurements taken to represent the minimal depth of tumor-free cervical stroma, i.e. the results of the measurements taken posteriorly and laterally. However, the limits of agreement were narrower and the ICC values were higher (0.74-0.92) for the depth of cervical stroma invasion and for the tumor size measurements. Histological examination revealed parametrial cancer infiltration in four patients, which was detected during ultrasound examination, with no false-positive results. Conclusions Transvaginal sonography is acceptably accurate for evaluation of tumor size and depth of cervical stroma invasion in clinical practice. Copyright (C) 2011 ISUOG. Published by John Wiley & Sons, Ltd.
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