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Sökning: WFRF:(Malek Sam)

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  • Andersson, Jesper, 1970-, et al. (författare)
  • Reflecting on self-adaptive software systems
  • 2009
  • Ingår i: Software Engineering for Adaptive and Self-Managing Systems, 2009. SEAMS '09. ICSE Workshop on. - 9781424437245 ; , s. 38-47
  • Konferensbidrag (refereegranskat)
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3.
  • Bajbouj, Malek, et al. (författare)
  • Two-year outcome of vagus nerve stimulation in treatment-resistant depression
  • 2010
  • Ingår i: Journal of Clinical Psychopharmacology. - : Lippincott Williams & Wilkins. - 0271-0749 .- 1533-712X. ; 30:3, s. 273-281
  • Tidskriftsartikel (refereegranskat)abstract
    • One of the major goals of antidepressant treatment is a sustained response and remission of depressive symptoms. Some of the previous studies of vagus nerve stimulation (VNS) have suggested antidepressant effects. Our naturalistic study assessed the efficacy and the safety of VNS in 74 European patients with therapy-resistant major depressive disorder. Psychometric measures were obtained after 3, 12, and 24 months of VNS. Mixed-model repeated-measures analysis of variance revealed a significant reduction (P < or = 0.05) at all the 3 time points in the 28-item Hamilton Rating Scale for Depression (HRSD28) score, the primary outcome measure. After 2 years, 53.1% (26/49) of the patients fulfilled the response criteria (> or =50% reduction in the HRSD28 scores from baseline) and 38.9% (19/49) fulfilled the remission criteria (HRSD28 scores < or = 10). The proportion of patients who fulfilled the remission criteria remained constant as the duration of VNS treatment increased. Voice alteration, cough, and pain were the most frequently reported adverse effects. Two patients committed suicide during the study; no other deaths were reported. No statistically significant differences were seen in the number of concomitant antidepressant medications. The results of this 2-year open-label trial suggest a clinical response and a comparatively benign adverse effect profile among patients with treatment-resistant depression.
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  • de Lemos, Rogerio, et al. (författare)
  • Software Engineering for Self-Adaptive Systems : A Second Research Roadmap
  • 2013
  • Ingår i: Software Engineering for Self-Adaptive Systems II. - Berlin, Heidelberg : Springer. - 9783642358128 ; , s. 1-32
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • The goal of this roadmap paper is to summarize the state-of-the-art and identify research challenges when developing, deploying and managing self-adaptive software systems. Instead of dealing with a wide range of topics associated with the field, we focus on four essential topics of self-adaptation: design space for self-adaptive solutions, software engineering processes for self-adaptive systems, from centralized to decentralized control, and practical run-time verification & validation for self-adaptive systems. For each topic, we present an overview, suggest future directions, and focus on selected challenges. This paper complements and extends a previous roadmap on software engineering for self-adaptive systems published in 2009 covering a different set of topics, and reflecting in part on the previous paper. This roadmap is one of the many results of the Dagstuhl Seminar 10431 on Software Engineering for Self-Adaptive Systems, which took place in October 2010.
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  • Vromant, Pieter, et al. (författare)
  • On interacting control loops in self-adaptive systems
  • 2011
  • Ingår i: Proceedings of the 6th International Symposium on Software Engineering for Adaptive and Self-Managing Systems. - New York, NY, USA : ACM Press. - 9781450305754 ; , s. 202-207
  • Bokkapitel (refereegranskat)
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9.
  • Weyns, Danny, et al. (författare)
  • Claims and Supporting Evidence for Self-Adaptive Systems : A Literature Study
  • 2012
  • Ingår i: ICSE Workshop on Software Engineering for Adaptive and Self-Managing Systems. - : IEEE. ; , s. 89-98
  • Konferensbidrag (refereegranskat)abstract
    • Despite the vast body of work on self-adaption, no systematic study has been performed on the claims associated with self-adaptation and the evidence that exists for these claims. As such an insight is crucial for researchers and engineers, we performed a literature study of the research results from SEAMS since 2006 and the associated Dagstuhl seminar in 2008. The study shows that the primary claims of self-adaptation are improved flexibility, reliability, and performance of the system. On the other hand, the tradeoffs implied by self-adaptation have not received much attention. Evidence is obtained from basic examples, or simply lacking. Few systematic empirical studies have been performed, and no industrial evidence is reported. From the study, we offer the following recommendations to move the field forward: to improve evaluation, researchers should make their assessment methods, tools and data publicly available; to deal with poor discussion of limitations, conferences/workshops should require an explicit section on limitations in engineering papers; to improve poor treatment of tradeoffs, this aspect should be an explicit subject of reviews; and finally, to enhance industrial validation, the best academy-industry efforts could be formally recognized by the community.
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10.
  • Weyns, Danny, et al. (författare)
  • FORMS : Unifying Reference Model for Formal Specification of Distributed Self-adaptive Systems
  • 2012
  • Ingår i: ACM Transactions on Autonomous and Adaptive Systems. - : ACM Press. - 1556-4665 .- 1556-4703. ; 7:1
  • Tidskriftsartikel (refereegranskat)abstract
    • The challenges of pervasive and mobile computing environments, which are highly dynamic and unpredictable, have motivated the development of self-adaptive software systems. Although noteworthy successes have been achieved on many fronts, the construction of such systems remains significantly more challenging than traditional systems. We argue this is partially because researchers and practitioners have been struggling with the lack of a precise vocabulary for describing and reasoning about the key architectural characteristics of self-adaptive systems. Further exacerbating the situation is the fact that existing frameworks and guidelines do not provide an encompassing perspective of the different types of concerns in this setting. In this article, we present a comprehensive reference model, entitled FOrmal Reference Model for Self-adaptation (FORMS), that targets both issues. FORMS provides rigor in the manner such systems can be described and reasoned about. It consists of a small number of formally specified modeling elements that correspond to the key concerns in the design of self-adaptive software systems, and a set of relationships that guide their composition. We demonstrate FORMS's ability to precisely describe and reason about the architectural characteristics of distributed self-adaptive software systems through its application to several existing systems. FORMS's expressive power gives it a potential for documenting reusable architectural solutions (e.g., architectural patterns) to commonly encountered problems in this area.
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  • Weyns, Danny, et al. (författare)
  • On Patterns for Decentralized Control in Self-Adaptive Systems
  • 2013
  • Ingår i: Software Engineering for Self-Adaptive Systems II. - Berlin, Heidelberg : Springer. - 9783642358128 ; , s. 76-107
  • Konferensbidrag (refereegranskat)abstract
    • Self-adaptation is typically realized using a control loop. Oneprominent approach for organizing a control loop in self-adaptive systemsis by means of four components that are responsible for the primary functionsof self-adaptation: Monitor, Analyze, Plan, and Execute, togetherforming a MAPE loop. When systems are large, complex, and heterogeneous,a single MAPE loop may not be sufficient for managing alladaptation in a system, so multiple MAPE loops may be introduced. Inself-adaptive systems with multiple MAPE loops, decisions about how todecentralize each of the MAPE functions must be made. These decisionsinvolve how and whether the corresponding functions from multiple loopsare to be coordinated (e.g., planning components coordinating to preparea plan for an adaptation). To foster comprehension of self-adaptive systemswith multiple MAPE loops and support reuse of known solutions,it is crucial that we document common design approaches for engineers.As such systematic knowledge is currently lacking, it is timely to reflecton these systems to: (a) consolidate the knowledge in this area, and (b)to develop a systematic approach for describing different types of controlin self-adaptive systems. We contribute with a simple notation fordescribing interacting MAPE loops, which we believe helps in achieving(b), and we use this notation to describe a number of existing patternsof interacting MAPE loops, to begin to fulfill (a). From our study, weoutline numerous remaining research challenges in this area.
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15.
  • Weyns, Danny, et al. (författare)
  • Perpetual assurances for self-adaptive systems
  • 2017
  • Ingår i: Software Engineeringfor Self-Adaptive Systems III, Assurances. - Cham : Springer. - 9783319741826 - 9783319741833 ; , s. 31-63
  • Bokkapitel (refereegranskat)abstract
    • Providing assurances for self-adaptive systems is challenging. A primary underlying problem is uncertainty that may stem from a variety of different sources, ranging from incomplete knowledge to sensor noise and uncertain behavior of humans in the loop. Providing assurances that the self-adaptive system complies with its requirements calls for an enduring process spanning the whole lifetime of the system. In this process, humans and the system jointly derive and integrate new evidence and arguments, which we coined perpetual assurances for self-adaptive systems. In this paper, we provide a background framework and the foundation for perpetual assurances for self-adaptive systems. We elaborate on the concrete challenges of offering perpetual assurances, requirements for solutions, realization techniques and mechanisms to make solutions suitable. We also present benchmark criteria to compare solutions. We then present a concrete exemplar that researchers can use to assess and compare approaches for perpetual assurances for self-adaptation. © Springer International Publishing AG 2017.
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