| 1. |
- Dujon, B, et al.
(författare)
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The nucleotide sequence of Saccharomyces cerevisiae chromosome XV
- 1997
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Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 387:6632, s. 98-102
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Tidskriftsartikel (refereegranskat)abstract
- Chromosome XV was one of the last two chromosomes of Saccharomyces cerevisiae to be discovered(1). It is the third-largest yeast chromosome after chromosomes XII and IV, and is very similar in size to chromosome VII. It alone represents 9% of the yeast genome (8% if ribosomal DNA is included). When systematic sequencing of chromosome XV was started, 93 genes or markers were identified, and most of them were mapped(2). However, very little else was known about chromosome XV which, in contrast to shorter chromosomes, had not been the object of comprehensive genetic or molecular analysis. It was therefore decided to start sequencing chromosome XV only in the third phase of the European Yeast Genome Sequencing Programme, after experience was gained on chromosomes III, XI and II (refs 3-5). The sequence of chromosome XV has been determined from a set of partly overlapping cosmid clones derived from a unique yeast strain, and physically mapped at 3.3-kilobase resolution before sequencing. As well as numerous new open reading frames (ORFs) and genes encoding tRNA or small RNA molecules, the sequence of 1,091,283 base pairs confirms the high proportion of orphan genes and reveals a number of ancestral and successive duplications with other yeast chromosomes.
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| 2. |
- Plompen, A. J. M., et al.
(författare)
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The joint evaluated fission and fusion nuclear data library, JEFF-3.3
- 2020
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Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 56:7
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Forskningsöversikt (refereegranskat)abstract
- The joint evaluated fission and fusion nuclear data library 3.3 is described. New evaluations for neutron-induced interactions with the major actinides 235U, 238U and 239Pu, on 241Am and 23Na, 59Ni, Cr, Cu, Zr, Cd, Hf, W, Au, Pb and Bi are presented. It includes new fission yields, prompt fission neutron spectra and average number of neutrons per fission. In addition, new data for radioactive decay, thermal neutron scattering, gamma-ray emission, neutron activation, delayed neutrons and displacement damage are presented. JEFF-3.3 was complemented by files from the TENDL project. The libraries for photon, proton, deuteron, triton, helion and alpha-particle induced reactions are from TENDL-2017. The demands for uncertainty quantification in modeling led to many new covariance data for the evaluations. A comparison between results from model calculations using the JEFF-3.3 library and those from benchmark experiments for criticality, delayed neutron yields, shielding and decay heat, reveals that JEFF-3.3 performes very well for a wide range of nuclear technology applications, in particular nuclear energy.
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| 3. |
- Milner, A, et al.
(författare)
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Gendered working environments as a determinant of mental health inequalities: a systematic review of 27 studies
- 2021
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Ingår i: Occupational and environmental medicine. - : BMJ. - 1470-7926 .- 1351-0711. ; 78:3, s. 147-152
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Tidskriftsartikel (refereegranskat)abstract
- ‘Gendered working environments’ describes the ways in which (1) differential selection into work, (2) variations in employment arrangements and working hours, (3) differences in psychosocial exposures and (4) differential selection out of work may produce varied mental health outcomes for men and women. The aim of this study was to conduct a systematic review to understand gender differences in mental health outcomes in relation to the components of gendered working environments.MethodsThe review followed a Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) search approach and focused on studies published in 2008–2018. The protocol for the review was prospectively registered with PROSPERO (CRD42019124066).FindingsAcross the 27 cohort studies included in the review, we found that (1) there was inconclusive evidence on the effect of occupational gender composition on the mental health of men and women, (2) women’s mental health was more likely to be affected by long working hours than men’s; however, precarious employment was more likely to be negatively associated with men’s mental health, (3) exposure to traditional constructs of psychosocial job stressors negatively affected the mental health of both women and men, and (4) unemployment and retirement are associated with poorer mental health in both genders.InterpretationThe findings from this review indicate that gendered working environments may affect the mental health of both men and women, but the association is dependent on the specific exposure examined. There is still much to be understood about gendered working environments, and future research into work and health should be considered with a gender lens.
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| 4. |
- Rochman, Dimitri, et al.
(författare)
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Efficient use of Monte Carlo : Uncertainty Propagation
- 2014
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Ingår i: Nuclear science and engineering. - 0029-5639 .- 1943-748X. ; 177:3, s. 337-349
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Tidskriftsartikel (refereegranskat)abstract
- A new and faster Total Monte Carlo method for the propagation of nuclear data uncertaintiesin Monte Carlo nuclear simulations is presented (the fast TMC method).It is addressing the main drawback of the original Total Monte Carlo method(TMC), namely the necessary large time multiplication factor compared to a singlecalculation. With this new method, Monte Carlo simulations can now be accompaniedwith uncertainty propagation (other than statistical), with small additionalcalculation time. The fast TMC method is presented and compared with the TMCand fast GRS methods for criticality and shielding benchmarks and burn-up calculations.Finally, to demonstrate the efficiency of the method, uncertainties on localdeposited power in 12.7 millions cells are calculated for a full size reactor core,
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| 5. |
- Rochman, D., et al.
(författare)
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Nuclear Data Uncertainties for Typical LWR Fuel Assemblies and a Simple Reactor Core
- 2017
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Ingår i: Nuclear Data Sheets. - : Elsevier BV. - 0090-3752 .- 1095-9904. ; 139, s. 1-76
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Tidskriftsartikel (refereegranskat)abstract
- Abstract The impact of the current nuclear data library covariances such as in ENDF/B-VII.1, JEFF-3.2, JENDL-4.0, SCALE and TENDL, for relevant current reactors is presented in this work. The uncertainties due to nuclear data are calculated for existing PWR and BWR fuel assemblies (with burn-up up to 40 GWd/tHM, followed by 10 years of cooling time) and for a simplified PWR full core model (without burn-up) for quantities such as k ∞ , macroscopic cross sections, pin power or isotope inventory. In this work, the method of propagation of uncertainties is based on random sampling of nuclear data, either from covariance files or directly from basic parameters. Additionally, possible biases on calculated quantities are investigated such as the self-shielding treatment. Different calculation schemes are used, based on CASMO, SCALE, DRAGON, MCNP or FISPACT-II, thus simulating real-life assignments for technical-support organizations. The outcome of such a study is a comparison of uncertainties with two consequences. One: although this study is not expected to lead to similar results between the involved calculation schemes, it provides an insight on what can happen when calculating uncertainties and allows to give some perspectives on the range of validity on these uncertainties. Two: it allows to dress a picture of the state of the knowledge as of today, using existing nuclear data library covariances and current methods.
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| 6. |
- Rochman, D., et al.
(författare)
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Nuclear data uncertainty for criticality-safety : Monte Carlo vs. linear perturbation
- 2016
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Ingår i: Annals of Nuclear Energy. - : Elsevier BV. - 0306-4549 .- 1873-2100. ; 92, s. 150-160
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Tidskriftsartikel (refereegranskat)abstract
- This work is presenting a comparison of results for different methods of uncertainty propagation due to nuclear data for 330 criticality-safety benchmarks. Covariance information is propagated to key using either Monte Carlo methods (NUSS: based on existing nuclear data covariances, and TMC: based on reaction model parameters) or sensitivity calculations from MCNP6 coupled with nuclear data covariances. We are showing that all three methods are globally equivalent for criticality calculations considering the two first moments of a distribution (average and standard deviation), but the Monte Carlo methods lead to actual probability distributions, where the third moment (skewness) should not be ignored for safety assessments.
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| 7. |
- Rochman, Dimitri, et al.
(författare)
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The TENDL library : Hope, reality and future
- 2017
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Ingår i: Nd 2016 Bruges. - Les Ulis : EDP Sciences. - 9782759890200
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Konferensbidrag (refereegranskat)abstract
- The TALYS Evaluated Nuclear Data Library (TENDL) has now 8 releases since 2008. Considerable experience has been acquired for the production of such general-purpose nuclear data library based on the feedback from users, evaluators and processing experts. The backbone of this achievement is simple and robust: completeness, quality and reproducibility. If TENDL is extensively used in many fields of applications, it is necessary to understand its strong points and remaining weaknesses. Alternatively, the essential knowledge is not the TENDL library itself, but rather the necessary method and tools, making the library a side product and focusing the efforts on the evaluation knowledge. The future of such approach will be discussed with the hope of nearby greater success.
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| 8. |
- Rochman, D., et al.
(författare)
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Uncertainty Propagation with Fast Monte Carlo Techniques
- 2014
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Ingår i: Nuclear Data Sheets. - : Elsevier BV. - 0090-3752 .- 1095-9904. ; 118, s. 367-369
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Tidskriftsartikel (refereegranskat)abstract
- Two new and faster Monte Carlo methods for the propagation of nuclear data uncertainties in Monte Carlo nuclear simulations are presented (the "Fast TMC" and "Fast GRS" methods). They are addressing the main drawback of the original Total Monte Carlo method (TMC), namely the necessary large time multiplication factor compared to a single calculation. With these new methods, Monte Carlo simulations can now be accompanied with uncertainty propagation (other than statistical), with small additional calculation time. The new methods are presented and compared with the TMC methods for criticality benchmarks.
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