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- Carvalho, ICS, et al.
(författare)
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Second order nonlinearities in optical fibers
- 2002
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Ingår i: Polymer Optical Fibers. - Los Angeles, CA, USA : American Scientific Publishers. - 9781588830128
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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- Etcheverry, Sebastián, et al.
(författare)
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Microsecond switching of plasmonic nanorods in an all-fiber optofluidic component
- 2017
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Ingår i: Optica. - : Optical Society of America. - 2334-2536. ; 4:8, s. 864-870
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Tidskriftsartikel (refereegranskat)abstract
- As information technologies move from electron-to photon-based systems, the need to rapidly modulate light is of paramount importance. Here, we study the evolution of the electric-field-induced alignment of gold nanorods suspended in organic solvents. The experiments were performed using an all-fiber optofluidic device, which enables convenient interaction of light, electric fields, and the nanorod suspension. We demonstrate microsecond nanorod switching times, three orders of magnitude faster than a traditional Freederickcz-based liquid crystal alignment mechanism. We find that the dynamics of the alignment agrees well with the Einstein-Smoluchowski relationship, allowing for the determination of the rotational diffusion coefficient and polarizability anisotropy of the nanorods as well as the effective length of the ligands capping the nanorods. The ability to dynamically control the optical properties of these plasmonic suspensions coupled with the point-to-point delivery of light from the fiber component, as demonstrated in this work, may enable novel ultrafast optical switches, filters, displays, and spatial light modulators.
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- Franciscangelis, C., et al.
(författare)
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Vibration measurement on composite material with embedded optical fiber based on phase-OTDR
- 2017
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Ingår i: Proceedings of SPIE - The International Society for Optical Engineering Volume 10168, Sensors and Smart Structures Technologies for Civil, Mechanical, and Aerospace Systems 2017; 101683Q (2017). - : SPIE. - 9781510608214
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Konferensbidrag (refereegranskat)abstract
- Distributed sensors based on phase-optical time-domain reflectometry (phase-OTDR) are suitable for aircraft health monitoring due to electromagnetic interference immunity, small dimensions, low weight and flexibility. These features allow the fiber embedment into aircraft structures in a nearly non-intrusive way to measure vibrations along its length. The capability of measuring vibrations on avionics structures is of interest for what concerns the study of material fatigue or the occurrence of undesirable phenomena like flutter. In this work, we employed the phase-OTDR technique to measure vibrations ranging from some dozens of Hz to kHz in two layers of composite material board with embedded polyimide coating 0.24 numerical aperture single-mode optical fiber. © 2017 SPIE.
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- Lane, J. C. E., et al.
(författare)
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Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study
- 2020
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Ingår i: Lancet Rheumatology. - : Elsevier BV. - 2665-9913. ; 2:11
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Tidskriftsartikel (refereegranskat)abstract
- Background Hydroxychloroquine, a drug commonly used in the treatment of rheumatoid arthritis, has received much negative publicity for adverse events associated with its authorisation for emergency use to treat patients with COVID-19 pneumonia. We studied the safety of hydroxychloroquine, alone and in combination with azithromycin, to determine the risk associated with its use in routine care in patients with rheumatoid arthritis. Methods In this multinational, retrospective study, new user cohort studies in patients with rheumatoid arthritis aged 18 years or older and initiating hydroxychloroquine were compared with those initiating sulfasalazine and followed up over 30 days, with 16 severe adverse events studied. Self-controlled case series were done to further establish safety in wider populations, and included all users of hydroxychloroquine regardless of rheumatoid arthritis status or indication. Separately, severe adverse events associated with hydroxychloroquine plus azithromycin (compared with hydroxychloroquine plus amoxicillin) were studied. Data comprised 14 sources of claims data or electronic medical records from Germany, Japan, the Netherlands, Spain, the UK, and the USA. Propensity score stratification and calibration using negative control outcomes were used to address confounding. Cox models were fitted to estimate calibrated hazard ratios (HRs) according to drug use. Estimates were pooled where the I-2 value was less than 0.4. Findings The study included 956 374 users of hydroxychloroquine, 310 350 users of sulfasalazine, 323 122 users of hydroxychloroquine plus azithromycin, and 351 956 users of hydroxychloroquine plus amoxicillin. No excess risk of severe adverse events was identified when 30-day hydroxychloroquine and sulfasalazine use were compared. Selfcontrolled case series confirmed these findings. However, long-term use of hydroxychloroquine appeared to be associated with increased cardiovascular mortality (calibrated HR 1.65 [95% CI 1.12-2.44]). Addition of azithromycin appeared to be associated with an increased risk of 30-day cardiovascular mortality (calibrated HR 2.19 [95% CI 1.22-3.95]), chest pain or angina (1.15 [1.05-1.26]), and heart failure (1.22 [1.02-1.45]). Interpretation Hydroxychloroquine treatment appears to have no increased risk in the short term among patients with rheumatoid arthritis, but in the long term it appears to be associated with excess cardiovascular mortality. The addition of azithromycin increases the risk of heart failure and cardiovascular mortality even in the short term. We call for careful consideration of the benefit-risk trade-off when counselling those on hydroxychloroquine treatment. Copyright (c) 2020 The Author(s). Published by Elsevier Ltd.
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- Laurell, Fredrik, et al.
(författare)
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Poled glasses
- 1998
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Ingår i: MRS bulletin. - 0883-7694 .- 1938-1425. ; 23, s. 31-35
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Tidskriftsartikel (refereegranskat)
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- Malmström, Mikael, 1982-, et al.
(författare)
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All-fiber polarization-maintaining electrooptic pulse-picker
- 2015
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Ingår i: Conference on Lasers and Electro-Optics Europe - Technical Digest. - : Institute of Electrical and Electronics Engineers Inc..
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Konferensbidrag (refereegranskat)abstract
- An alignment free all-fiber pulse-picker running at variable repetition-rate for selecting pulses from an 86 MHz mode-locked Yb-fiber laser at 0-0.6 MHz with better than 35 dB extinction ratio is presented.
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| 23. |
- Malmström, Mikael, 1982-, et al.
(författare)
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Q-switched all-fiber Ytterbium laser with an integrated polarization switch
- 2010
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Ingår i: 4th EPS-QEOD Europhoton Conference. - 2914771649
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Konferensbidrag (refereegranskat)abstract
- An all-fiber nanosecond risetime polarizationswitch is employed in an Ytterbium cavity. Thepulsed laser operation is polarized and in the1 μm wavelength range. The main optical outputcharacteristics are: repetition rate of 2 kHz,pulse energy of 13 uJ, and peak powers close to 90Watts.
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- Myrén, Niklas, et al.
(författare)
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Systems measurements of 2x2 poled fiber switch
- 2005
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Ingår i: IEEE Photonics Technology Letters. - 1041-1135 .- 1941-0174. ; 17:12, s. 2571-2573
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Tidskriftsartikel (refereegranskat)abstract
- The performance of a 2x2 all-fiber electrooptical switch is characterized in a system at up to 40 Gb/s. Error-free transmission is demonstrated. The device was also employed as a protection switch at 10 Gb/s in an installed fiber link.
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