| 1. |
- Arjonen, Antti, et al.
(författare)
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Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis
- 2014
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Ingår i: Journal of Clinical Investigation. - : American Society for Clinical Investigation. - 0021-9738 .- 1558-8238. ; 124:3, s. 1069-1082
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Tidskriftsartikel (refereegranskat)abstract
- Mutations of the tumor suppressor TP53 are present in many forms of human cancer and are associated with increased tumor cell invasion and metastasis. Several mechanisms have been identified for promoting dissemination of cancer cells with TP53 mutations, including increased targeting of integrins to the plasma membrane. Here, we demonstrate a role for the filopodia-inducing motor protein Myosin-X (Myo10) in mutant p53-driven cancer invasion. Analysis of gene expression profiles from 2 breast cancer data sets revealed that MYO10 was highly expressed in aggressive cancer subtypes. Myo10 was required for breast cancer cell invasion and dissemination in multiple cancer cell lines and murine models of cancer metastasis. Evaluation of a Myo10 mutant without the integrin-binding domain revealed that the ability of Myo10 to transport 131 integrins to the filopodia tip is required for invasion. Introduction of mutant p53 promoted Myo10 expression in cancer cells and pancreatic ductal adenocarcinoma in mice, whereas suppression of endogenous mutant p53 attenuated Myo10 levels and cell invasion. In clinical breast carcinomas, Myo10 was predominantly expressed at the invasive edges and correlated with the presence of TP53 mutations and poor prognosis. These data indicate that Myo10 upregulation in mutant p53-driven cancers is necessary for invasion and that plasma-membrane protrusions, such as filopodia, may serve as specialized metastatic engines.
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| 2. |
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| 3. |
- Cervantes, Sandra, et al.
(författare)
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Strong Purifying Selection in Haploid Tissue-Specific Genes of Scots Pine Supports the Masking Theory
- 2023
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Ingår i: Molecular biology and evolution. - : Oxford University Press. - 0737-4038 .- 1537-1719. ; 40:8
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Tidskriftsartikel (refereegranskat)abstract
- The masking theory states that genes expressed in a haploid stage will be under more efficient selection. In contrast, selection will be less efficient in genes expressed in a diploid stage, where the fitness effects of recessive deleterious or beneficial mutations can be hidden from selection in heterozygous form. This difference can influence several evolutionary processes such as the maintenance of genetic variation, adaptation rate, and genetic load. Masking theory expectations have been confirmed in single-cell haploid and diploid organisms. However, in multicellular organisms, such as plants, the effects of haploid selection are not clear-cut. In plants, the great majority of studies indicating haploid selection have been carried out using male haploid tissues in angiosperms. Hence, evidence in these systems is confounded with the effects of sexual selection and intraspecific competition. Evidence from other plant groups is scarce, and results show no support for the masking theory. Here, we have used a gymnosperm Scots pine megagametophyte, a maternally derived seed haploid tissue, and four diploid tissues to test the strength of purifying selection on a set of genes with tissue-specific expression. By using targeted resequencing data of those genes, we obtained estimates of genetic diversity, the site frequency spectrum of 0-fold and 4-fold sites, and inferred the distribution of fitness effects of new mutations in haploid and diploid tissue-specific genes. Our results show that purifying selection is stronger for tissue-specific genes expressed in the haploid megagametophyte tissue and that this signal of strong selection is not an artifact driven by high expression levels.
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| 4. |
- Guo, Li, et al.
(författare)
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Design of a garment-based sensing system for breathing monitoring
- 2013
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Ingår i: Textile research journal. - : SAGE Publications. - 0040-5175 .- 1746-7748. ; 83:5, s. 499-509
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Tidskriftsartikel (refereegranskat)abstract
- The long-term monitoring of biophysiological signals requires new types of sensor systems that are wearable and at the same time convenient for the users. This paper describes the design of a novel garment-based sensing system for the long-term monitoring of breathing rhythm. The system concept was realized in a prototype garment, integrated with coated piezoresistive sensors. The prototype garment was tested by five subjects, and compared with a standard piezoelectric respiratory belt. Each signal was quantitatively and qualitatively evaluated in the time and frequency domain to make sure that no medical and diagnostic information was lost. The results showed a good agreement between the garment-based sensors and the standard reference, where errors occurred only when the breathing rate was extremely high. The garment-based sensor system could also distinguish the predominance breathing compartment (chest versus abdominal breathing). The system could detect a 10 s pause in breathing, which could be of importance in studies of sleep apnea. A garment-based sensing system maintains the accuracy of the signal quality without reducing the comfort for the user. It makes possible long-term ambulatory monitoring and has home-based healthcare applications.
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| 5. |
- Guo, Li, et al.
(författare)
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Disappearing Sensors. Textile Based Sensors for Monitoring Breathing
- 2011
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Konferensbidrag (refereegranskat)abstract
- Textile based sensors were developed and used for remote monitoring of breathing. The breathing is simulated by using a new cyclic tester device. In the simulated a cyclic force is applied along the length of the textile sensor. However due to the morphology of human body, in real situation the sensor is not only under stretching but also under a certain degree of bending. A prototype garment with the sensor situated on the chest area was made. The prototype was worn by 10 persons, and breathing was recorded as the persons were sitting still, walking and jogging. Deep breathing in the supine position and breathing with a method called athletic breathing were used to evaluate the sensor. A testing circuit and a Labview program were made for preliminary test. The sensor is wearable, washable and comfortable. Sensor construction is totally ‘disappearing’ and visualize as printed pattern onto the surface of garment.
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| 6. |
- Guo, Li, et al.
(författare)
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Improvement of Electro-Mechanical Properties of Strain Sensors made of elastic-conductive hybrid yarns
- 2012
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Ingår i: Textile research journal. - : SAGE Journals. - 0040-5175 .- 1746-7748. ; 82:19, s. 1937-1947
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Tidskriftsartikel (refereegranskat)abstract
- Fabric-based strain sensors have been developed using different technologies, among which flat knitting is one of the most effective and economical methods. However, knitted strain sensors are not often used in practical applications because the sensors usually exhibit large elastic hysteresis when they are deformed and subjected to stress during application. One possible approach to overcome these shortcomings is to introduce elastic properties at the yarn level by combining the conductive materials with elastic materials. In this paper, we demostrate a hybrid yarn made of a conductive yarn that winds around an elastic core yarn in a direct twisting device. The electro-mechanical properties of strain sensors knitted from the hybrid yarns were tested in order to characterize the sensors. This study consisted of two stages: the yarn preparation and the sensor characterization. In the first stage, two kinds of elastic core components (polyamide/Lycra and polyamide) and two kinds of conductive winding yarns (Bekinox BK50/1 and Bekinox BK50/2) were selected for twisting. The twisting was done with a constant twisting speed and four different numbers of twists. Mechanical properties, that is, the tenacity, force at break and elongation at break, were tested in order to determine the optimal parameters for producing the hybrid yarns. The results indicated that among the tested yarns those with a polyamide core and Bekinox BK50/1 winding yarns at 450 twist/meter and with a polyamide/Lycra core and Bekinox BK 50/2 winding yarns at 600 twist/meter had the best properties. These were thus selected as the materials for producing knitted strain sensors. In the second stage, electro-mechanical properties of the knitted strain sensors were determined under tensile stress and multi-cyclic tensile stress. The results show that the hybrid yarns can effectively enhance the
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| 7. |
- Guo, Li, et al.
(författare)
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Textile Strain Sensors Characterization- Sensitivity, Linearity, Stability and Hysteresis
- 2010
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Ingår i: Nordic Textile Journal. ; :2, s. 51-63
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Tidskriftsartikel (refereegranskat)abstract
- In this paper 4 different textile based strain sensors for measuring different level of strains were presented. Sensor consist a conductive part formed by coating or weaving technique. Both elastic and inelastic textile substrates were selected to achieve the required stains in applications. Sensor configuration was characterized using a tensile tester and measuring the resistance parallel by microprocessor. A linear working range with transfer function of each sensor was found. Coated sensor gives a good stability, while woven sensor was relative less stable. Inelastic textile substrate reduces the hysteresis error caused by refraction and construction of materials. The sensitivities were between 2.5 to 9 vary with different sensors. This paper finished by a discussion of how to choose sensors with different applications, among which sensor function and processability are most important aspects to be considering.
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| 8. |
- Hernández, Niina
(författare)
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A Systematic Model for Improving Theoretical Garment Fit
- 2018
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Ingår i: Journal of Fashion Marketing and Management. - : Emerald Group Publishing Limited. - 1361-2026. ; 22:4, s. 527-539
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Tidskriftsartikel (refereegranskat)abstract
- PurposeThe purpose of this paper is to use a systematic model for detecting misfit between the garment and the target group.Design/methodology/approachUsing an empirical–analytical methodology, the systematic model was tested. The input data were run through the model to generate the output data, which were analysed, including basic statistics. The purpose of the analysis was to detect misfit and improve the garment measurement chart. This procedure was repeated until a clear result was reached.FindingsThe result of this study is an optimised garment measurement chart, which considers the garment’s ease, different sizes/proportions in relation to a target group. The results show that it is possible to use a systematic model to define the shortcomings of a garment´s range of sizes and proportions.Research limitations/implicationsFurther studies are needed to verify the results of the theoretical garment fit and their values in relation to real garment fit.Practical implicationsIf the systematic model is implemented to improve the theoretical garment fit, this may have effects on the available garment sizes and its proportions, resulting in increased theoretical garment fit for the target group.Originality/valueThe paper presents a systematic model for detecting and eliminating theoretical fitting; the model includes both garment ease allowance and defined points of misfit.
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| 9. |
- Hernández, Niina, et al.
(författare)
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Can Virtually Trying on Apparel Help in Selecting the Correct Size?
- 2019
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Ingår i: Clothing & Textiles Research Journal. - : Sage Publications. - 0887-302X .- 1940-2473.
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Tidskriftsartikel (refereegranskat)abstract
- Close to 30% of garments bought online are returned, often due to issues of fit. These issues often relate to size selection, which is challenging without physically trying on a garment. Alternative methods need to be explored to select the best size in lieu of physically trying apparel on. To address this issue, we compare the size selections based on primary measurements and size charts, virtual garments, and real garments. A cross-sectional quantitative survey was carried out in an experimental setting. The participants (36, predominantly White females, aged 21–56) made size selections and evaluations based on virtual and real blouses and trousers. Selecting the size based on virtual garments is more accurate than size selection based on primary measurements and size charts, scoring 57% and 42%, respectively. Further research should be used to improve the virtual fitting room, with benefits such as fewer returns and more satisfied customers.
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| 10. |
- Hernández, Niina, et al.
(författare)
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Garment fit by numbers : Statistical identification of a garment's misfit
- 2014
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Konferensbidrag (refereegranskat)abstract
- A challenge for manufacturers of garments is to decide which sizes to make available for a potential target group. Mismatches between the garment’s sizes/proportions and a target group will decrease its fit and increase loss of sales. The purpose of this study is to develop a systematic model to identify and optimize the distribution of a garment’s sizes and proportions in order to provide a target group appropriate fit. This study is based on sample-garment measurements, experienced-based values and data containing body measurements of 2208 individuals. Statistical data from the case were analysed to find a model to detect mismatches between standard garments and a target group. The results show that it is possible to use a systematic model to define the shortcomings of a garment´s range of sizes and proportions. If implemented, this could have effects on the available garment sizes and its proportions, resulting an increased garment fit for a target group.
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| 11. |
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| 12. |
- Kajander, Kajsa, et al.
(författare)
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Elevated pro-inflammatory and lipotoxic mucosal lipids characterise irritable bowel syndrome
- 2009
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Ingår i: World Journal of Gastroenterology. - : Baishideng Publishing Group Co., Limited. - 1007-9327 .- 2219-2840. ; 15:48, s. 6068-6074
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Tidskriftsartikel (refereegranskat)abstract
- AIM: To investigate the pathophysiology of irritable bowel syndrome (IBS) by comparing the global mucosal metabolic profiles of IBS patients with those of healthy controls.METHODS: Fifteen IBS patients fulfilling the Rome II criteria, and nine healthy volunteers were included in the study. A combined lipidomics (UPLC/MS) and metabolomics (GC x GC-TOF) approach was used to achieve global metabolic profiles of mucosal biopsies from the ascending colon.RESULTS: Overall, lipid levels were elevated in patients with IBS. The most significant upregulation was seen for pro-inflammatory lysophosphatidylcholines. Other lipid groups that were significantly upregulated in IBS patients were lipotoxic ceramides, glycosphingolipids, and di- and triacylglycerols. Among the metabolites, the cyclic ester 2(3H)-furanone was almost 14-fold upregulated in IBS patients compared to healthy subjects (P = 0.03).CONCLUSION: IBS mucosa is characterised by a distinct pro-inflammatory and lipotoxic metabolic profile. Especially, there was an increase in several lipid species such as lysophospholipids and ceramides.
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| 13. |
- Larsson, Jonas, et al.
(författare)
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The Knit on Demand Supply Chain
- 2012
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Ingår i: AUTEX Research Journal. - : Versita. - 1470-9589 .- 2300-0929. ; 12:3, s. 67-75
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Tidskriftsartikel (refereegranskat)abstract
- As customers’ tastes become more differentiated, so must companies’ offerings evolve. The demand for variety may soon become unmanageable, and several companies are addressing this trend by adopting a system of mass customisation. One project, Knit on Demand, has been conducted by the Swedish School of Textiles in close collaboration with a knitting company and a retailer of tailored fashion in Stockholm. Production and sales of customised products pose logistical challenges for the companies involved, including the one-piece flow through almost the entire supply chain and the demand for short lead times in an otherwise slow environment, adding to the cost of manufacturing mass customised garments. Customisation has logistical benefits such as minimized inventory; hence, high inventory turnover and the possibility of fast response to meet customer demand. The Knit on Demand concept can be considered as leagile because it comprises both lean and agile components. It is lean in the manufacturing stage upstream and agile downstream to better respond to customer demand on the market.
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| 14. |
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| 15. |
- Mattila, Heikki, 1947-
(författare)
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Digital fashion - how and when?
- 2016
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Konferensbidrag (refereegranskat)abstract
- Virtual Reality and 3D systems are widely in use in many industries, both for design and marketing. Automobiles are designed by 3D systems, and the same images are further used in sales promotion and also in sales configurations. 3D design systems are also used by several fashion companies. But only a few go beyond that and present virtual products in web sites and in configurator applications like the famous Sales Wall by Adidas, which is regarded to be the company at the forefront in virtualization in fashion.3D software solutions are widely available. Lectra offers tools for designers while Browzwear, Optitex and Clo3D go further by integrating the 3D designs to sales configuration solutions including moving avatars. The Korean golf wear manufacturer Elrod organizes virtual cat walks for presenting their garments, where nothing, i.e. models (avatars), garments, cat walk and scenery, is real. The visual quality of avatars and garments improves continuously. Furthermore, such systems make customized e commerce possible. The aim of the recently completed Horizon 2020 funded project 'fromROLLtoBAG' was to create an integrated consumer driven local production system with the help of virtual design and digital manufacturing. Consumers connected with mobile devices can customize the avatar, insert own measurements and virtually try on garments from suppliers’ collection. Once done the order is transferred to a local manufacturer which with digital printing, cutting and unit assembly produces the product and ships to the customer in one day. Besides offering digital market place to brand companies, the objective of the project was to bring garment production back to Europe.
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| 16. |
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| 17. |
- Mustonen, Milka, et al.
(författare)
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Success indicators in various fashion business models
- 2013
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Ingår i: Journal of Global Fashion Marketing. - : Taylor & Francis Asia Pacific. - 2093-2685 .- 2325-4483. ; 4:2, s. 74-92
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this study was to analyze the business models of various fashion companies, based on their 2009 financial indicators, to understand how different operation models correlate with success and whether selected performance indicators monitor operational success. Based on their business models, the companies were classified as follows: brand retailers, brand marketers, luxury brands, and multi-brand retailers. Brand retailers with a high net profit margin and a rapid turnover of inventory were significantly more profitable than traditional multi-brand retailers. Luxury brand companies were another successful group. Though their stockturn was low, their net profit was high because of their unique design and high brand value. Brand marketers could adapt well to rapid changes, because their business was primarily based on intangible assets. Furthermore, multi-brand retailers showed the lowest financial ratios because of their slow stockturn and low net profit margin.
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| 18. |
- Oresic, Matej, 1967-, et al.
(författare)
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Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes
- 2008
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Ingår i: Journal of Experimental Medicine. - New York, USA : Rockefeller University Press. - 0022-1007 .- 1540-9538. ; 205:13, s. 2975-2984
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Tidskriftsartikel (refereegranskat)abstract
- The risk determinants of type 1 diabetes, initiators of autoimmune response, mechanisms regulating progress toward beta cell failure, and factors determining time of presentation of clinical diabetes are poorly understood. We investigated changes in the serum metabolome prospectively in children who later progressed to type 1 diabetes. Serum metabolite profiles were compared between sample series drawn from 56 children who progressed to type 1 diabetes and 73 controls who remained nondiabetic and permanently autoantibody negative. Individuals who developed diabetes had reduced serum levels of succinic acid and phosphatidylcholine (PC) at birth, reduced levels of triglycerides and antioxidant ether phospholipids throughout the follow up, and increased levels of proinflammatory lysoPCs several months before seroconversion to autoantibody positivity. The lipid changes were not attributable to HLA-associated genetic risk. The appearance of insulin and glutamic acid decarboxylase autoantibodies was preceded by diminished ketoleucine and elevated glutamic acid. The metabolic profile was partially normalized after the seroconversion. Autoimmunity may thus be a relatively late response to the early metabolic disturbances. Recognition of these preautoimmune alterations may aid in studies of disease pathogenesis and may open a time window for novel type 1 diabetes prevention strategies.
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| 19. |
- Pal, Rudrajeet, et al.
(författare)
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Antecedents of organizational resilience in economic crises : an empirical study of Swedish textile and clothing SMEs
- 2014
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Ingår i: International Journal of Production Economics. - : Elsevier. - 0925-5273 .- 1873-7579. ; 147, s. 410-428
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Tidskriftsartikel (refereegranskat)abstract
- Economic recessions have created challenges for small and medium-sized enterprises (SMEs) and contributed to disruptions requiring them to be resilient. At times of economic crises, SMEs face major threats to their financial performance and ultimately to their survival. The average number of Swedish textile and clothing (T&C) firms that went bankrupt during the recent crisis (2007–09) escalated twofold compared to the average over 2000–10. Following the 1990s economic crisis nearly 12 per cent of the T&C companies went bankrupt in 1994–95. The structural industrial statistics also plummeted in these crisis years, aggravating many internal problems in SMEs as a ripple effect. This study concentrates on the constraints faced by Swedish textile-related SMEs, primarily during the economic crises of the past two decades (1990–93 and end 2007–09), and identifying the antecedents and their different degrees of influence on economic resilience. It also deepens the understanding of the underlying patterns in the antecedents, observed in SMEs, favouring or inhibiting resilience due to their significance or deficit, respectively. The paper adopts an exploratory research conducted in two phases, first through a survey and followed by a series of interviews, responded by eight Swedish T&C SMEs. Annual reports provide a detailed account of the financial performances of these firms. A conceptual resilience framework was developed earlier, based on a review of extant literature. Findings provide insight on how the responding firms considered resourcefulness, viz. cash flow and investment finance, relational networks and material assets, along with ‘dynamic competitiveness’ through strategic and operational flexibility to be key enablers of resilience and financial performance, mostly through generation of profitability, cash flow/liquidity and sales turnover. Responses also highlighted the indirect influence of the ‘soft’ learning and cultural aspects like attentive leadership and collectiveness on economic resilience, considered tacit and ingrained in small or medium-sized family businesses. Additional process initiatives, in particular growth and continuity strategies, were also emergent patterns to properly utilize and direct the antecedents for resilience development. These are beneficial for firms to understand the key areas, in which to invest for developing resilient business models.
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| 20. |
- Pal, Rudrajeet, et al.
(författare)
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Local fashion value chains: Success factors and competitive advantages
- 2016
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Ingår i: Textiles: Inseperable from the human environment. - 9788392861850 ; , s. 631-638
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Konferensbidrag (refereegranskat)abstract
- Globalization had forced fashion companies to move their manufacturing to low cost bases. However, in the recent times several challenges like poor transparency, ethical issues, high transportation costs, long lead times, etc. have motivated major reshoring initiatives. Steadily the fashion companies in the west are relocating back their production and are motivated by trends of greater product customization, supply chain transparency and digital technologies. In addition, several initiatives have been launched to support this development, for example the US initiatives: [TC]2 “Reshoring Fashion Initiative” and “Apparel Made for You”. However detailed scholarly discussion on what enables success of such local fashion value chain models are limited. This paper explores the drivers, critical success factors and competitive advantages in designing such local fashion value chains by drawing inferences from a European initiative called “fromRolltoBag”. An action research is employed to collect empirical data through observations and interviews with the project stakeholders. Results show that the competitive success lies in designing a consumer-driven, digitally-enabled fashion value chain, enabled by the strategy of differentiation through: (i) advanced digitalization of design and manufacturing operations, (ii) flexible, integrated and agile operations, and (iii) enhanced customer experience/interaction with the extended product-service system.
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| 21. |
- Pal, Rudrajeet, et al.
(författare)
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Organisational resilience and health of business systems
- 2011
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Ingår i: International Journal of Business Continuity and Risk Management (IJBCRM). - : Inderscience Publishers. - 1758-2164 .- 1758-2172. ; 2:4, s. 372-398
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Tidskriftsartikel (refereegranskat)abstract
- Resilience in organisations is requisite for success and survival and a lack of it can lead to catastrophic organisational failures or bankruptcies in today’s turbulent and uncertain environment. The paper outlines an investigation to relate organisational resilience (ORes) to its business ‘health’ between 1989 and 2009, in terms of economic viability. The results are manifold viz. conceptualisation of business ‘health’ and ORes and, subsequent, operationalisation of the relationship through empirical findings. Financial statements (1989 to 2009) of 20 textile, clothing and fashion (TCF)-related companies in Sweden are analysed to draw necessary conclusions. The study uses the Altman’s Z-score as an indicator of business ‘health’ which includes discriminant ratios related to both short-term and long-term goals of a firm. Furthermore, the Z-score transition profile helps the company to judge its business ‘health’ and ORes, amidst crisis, and analyse further the underpinning attributes. This can be a helpful tool for companies to benchmark themselves to its competitors. Further research would help to find what differentiates the successful firm from the failing ones.
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| 22. |
- Pal, Rudrajeet, et al.
(författare)
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Organizational Resilience and Health of Business Systems
- 2011
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Konferensbidrag (refereegranskat)abstract
- Organizational failures are consequences of lack of resilience in today’s uncertain environment. Recent researches have delved into understanding various resilience attributes and frameworks but, explicitly, the property of resilience cannot be directly observable making it important to be related to more tangible and measurable organizational aspects. We define resilience as the business system’s ability to maintain a growing or constant ‘healthy’ state over time, despite being subjected to negative and/or destructive events, or to make a quick positive turnaround from one state to the other to finally enter the ‘healthy’ state. In the paper, organization’s ‘healthiness’ is represented in terms of its economic viability (profitability, shareholder’s value, perceived customer equity), using Altman’s Z-score with the aim to categorize the companies into ‘healthy’, ‘unhealthy’ and ‘catastrophic’ states, over timeline. The Z-scores are calculated from the annual financial reports for 20 Swedish textile and clothing companies, sampled out selectively, for 21 years using similar criteria of economic viability based on profitability, solvency, liquidity etc. as used to define organization’s ‘healthiness’, qualitatively. An attempt is taken to relate the Z-Score trends to transitions in business ‘health’, using an aggregate scoring system, over two major economic crises in Sweden (1989-93 and 2007-09) and the recovery period in between; to investigate whether these companies showed signs of resilient behaviour. The aim is to find out how economic indicators investigated over a time-period can reflect ‘healthiness’ of businesses and its resilience.
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| 23. |
- Pal, Rudrajeet, et al.
(författare)
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The quest for continual growth in textiles : innovation diversity and organizational resiliency
- 2013
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Ingår i: Proceedings of the 13th AUTEX conference, 22-24 May 2013, Dresden, Germany. - : AUTEX World Textile Conference 2013. - 9783867803434
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Konferensbidrag (refereegranskat)abstract
- The looming spectre of decline of the man-made fibre industry in US, Europe and Japan has been exacerbated by several problems like intense global cost pressure, fibre and raw material shortages, oil price volatility challenges etc. All of these have contributed to sluggish growth and higher bankruptcies. Resiliency in such a context has become a prerequisite for leading long term business prosperity fuelled by diverse technological innovations. In this paper, the authors have investigated an inexorable phenomenon of quantifying and correlating innovation and business resiliency from annual financial data for DuPont, as a case, over a span of five decades. The findings are manifold. The financial impact of blockbuster products based on disruptive technologies takes over a decade to yield results while contributions from sustaining innovations are swift. Both types of innovations are necessary. Incremental innovations delay product maturity with concomitant investments in costly and risky blockbuster product developments. From DuPont’s perspective, the company showed explosive growth from 1970-90, primarily fuelled by the rapid introduction of products with long product lifecycle developed during 1950-1965. However, DuPont performance started to indicate declining resiliency even while increasing investments in innovation, from 1960-2010. This is possibly due to change in product portfolio from commodity to specialty orientation.
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| 24. |
- Peterson, Joel, et al.
(författare)
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Mass customisation of flat knitted fashion products : simulation of the co-design process
- 2011
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Ingår i: Autex Research Journal. - : Autex. ; 11:1, s. 6-13
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Tidskriftsartikel (refereegranskat)abstract
- In 1995, the Japanese manufacturer Shima Seiki introduced the first complete garment knitting machine capable of producing a ready-made flat knitted article under the trade name WholeGarment. Recently, the company also developed a co-design software tool, Ordermade WholeGarment®, for the customisation of knitted fashion garments. Factory Boutique Shima, their retail shop for on-demand production of customised knitted garments, makes it possible for clients to modify a knitted garment according to personal taste in style, colour, pattern and size. This study examines how such a process streamlines the interaction between customer and shop personnel, while expediting the programming of the knitting machine. In comparing the manual co-design process with the Ordermade WholeGarment® system, we used a computer simulation to analyse the efficiency and lead times of each concept. The case study method was employed with an inductive approach based on company visits and interviews.
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| 25. |
- Peterson, Joel, et al.
(författare)
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Mass customisation of knitted fashion garments : Factory Boutique Shima – a case study
- 2010
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Ingår i: International Journal of Mass Customisation. - : Inderscience Publishers. - 1742-4208. ; 3:3, s. 247-258
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Tidskriftsartikel (refereegranskat)abstract
- Complete garment knitting technology makes it possible to produce a ready-made flat-knitted garment directly on the knitting machine without time-consuming post-knitting processes such as cutting and sewing. Factory Boutique Shima in Japan, a shop for on-demand production of customised knitted garments, uses a complete garment technology for customisation. Here, a customer can be a codesigner and customise a garment in accordance with his/her personal taste in style, material, pattern and colour. The aim of this paper is to present an example of how complete garment knitting technology has been used for mass customisation of knitted products by studying Factory Boutique Shimas's design and production concept. The method employed is an inductive approach based on company visits and interviews.
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