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1.	Baharom, F, et al. (author) Visualization of early influenza A virus trafficking in human dendritic cells using STED microscopy 2017 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 12:6, s. e0177920- Journal article (peer-reviewed)
2.	Cohn, L, et al. (author) Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation 2013 In: The Journal of experimental medicine. - : Rockefeller University Press. - 1540-9538 .- 0022-1007. ; 210:5, s. 1049-1063 Journal article (peer-reviewed)abstract Human BDCA3+ dendritic cells (DCs), the proposed equivalent to mouse CD8α+ DCs, are widely thought to cross present antigens on MHC class I (MHCI) molecules more efficiently than other DC populations. If true, it is unclear whether this reflects specialization for cross presentation or a generally enhanced ability to present antigens on MHCI. We compared presentation by BDCA3+ DCs with BDCA1+ DCs using a quantitative approach whereby antigens were targeted to distinct intracellular compartments by receptor-mediated internalization. As expected, BDCA3+ DCs were superior at cross presentation of antigens delivered to late endosomes and lysosomes by uptake of anti-DEC205 antibody conjugated to antigen. This difference may reflect a greater efficiency of antigen escape from BDCA3+ DC lysosomes. In contrast, if antigens were delivered to early endosomes through CD40 or CD11c, BDCA1+ DCs were as efficient at cross presentation as BDCA3+ DCs. Because BDCA3+ DCs and BDCA1+ DCs were also equivalent at presenting peptides and endogenously synthesized antigens, BDCA3+ DCs are not likely to possess mechanisms for cross presentation that are specific to this subset. Thus, multiple DC populations may be comparably effective at presenting exogenous antigens to CD8+ T cells as long as the antigen is delivered to early endocytic compartments.
3.	Salome, B, et al. (author) NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer 2022 In: Cancer cell. - : Elsevier BV. - 1878-3686 .- 1535-6108. ; 40:9, s. 1027- Journal article (peer-reviewed)
4.	Smed-Sorensen, A, et al. (author) Influenza A virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells 2012 In: PLoS pathogens. - : Public Library of Science (PLoS). - 1553-7374. ; 8:3, s. e1002572- Journal article (peer-reviewed)

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Type of publication: journal article (4)

Type of content: peer-reviewed (4)

Author/Editor: Mellman, I (4); Chalouni, C (3); Smed-Sorensen, A (3); Nakamura, N (2); Chatterjee, B (2); Cohn, L (2); show more...; Delamarre, L (2); Zhu, J. (1); Wang, L (1); Martin, M. (1); Lee, B. (1); Hammer, C (1); Wiklund, P (1); Bhardwaj, N (1); Malmberg, KJ (1); Romero, P (1); Mehrazin, R (1); Horowitz, A (1); Taylor, N (1); Baharom, F (1); Thomas, OS (1); Lepzien, R (1); Bieber, C (1); Ranti, D (1); Sfakianos, JP (1); Marcenaro, E. (1); Wang, YC (1); Kim-Schulze, S (1); Carrington, M (1); Palmer, D. (1); Brody, R (1); Esselborn, F (1); Lee, BC (1); Vandlen, R (1); Keler, T (1); Lauer, P (1); Brockstedt, D (1); Daza, J (1); Charap, A (1); Kelly, G. (1); Galsky, MD (1); Hammond, S (1); Wang, YA (1); Izadmehr, S (1); Geanon, D (1); Mace, EM (1); Sebra, RP (1); Salome, B (1); Banchereau, R (1); Farkas, AM (1); show less...

University: Karolinska Institutet (4)

Language: English (4)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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