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Sökning: WFRF:(Mladenović M)

  • Resultat 1-13 av 13
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  • Cattaneo, C, et al. (författare)
  • Simultaneous Onset of Haematological Malignancy and COVID: An Epicovideha Survey
  • 2022
  • Ingår i: Cancers. - : MDPI AG. - 2072-6694. ; 14:22
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The outcome of patients with simultaneous diagnosis of haematological malignancies (HM) and COVID-19 is unknown and there are no specific treatment guidelines. Methods: We describe the clinical features and outcome of a cohort of 450 patients with simultaneous diagnosis of HM and COVID-19 registered in the EPICOVIDEHA registry between March 2020 to February 2022. Results: Acute leukaemia and lymphoma were the most frequent HM (35.8% and 35.1%, respectively). Overall, 343 (76.2%) patients received treatment for HM, which was delayed for longer than one month since diagnosis in 57 (16.6%). An overall response rate was observed in 140 (40.8%) patients after the first line of treatment. After a median follow-up of 35 days, overall mortality was 177/450 (39.3%); 30-day mortality was significantly higher in patients not receiving HM treatment (42.1%) than in those receiving treatment (27.4%, p = 0.004), either before and/or after COVID-19, or compared to patients receiving HM treatment at least after COVID-19 (15.2%, p < 0.001). Age, severe/critical COVID-19, ≥2 comorbidities, and lack of HM treatment were independent risk factors for mortality, whereas a lymphocyte count >500/mcl at COVID-19 onset was protective. Conclusions: HM treatment should be delivered as soon as possible for patients with simultaneous diagnosis of COVID-19 and HM requiring immediate therapy.
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  • Krajcarz, M., et al. (författare)
  • The history of the domestic cat in Central Europe
  • 2022
  • Ingår i: Antiquity. - : Antiquity Publications. - 0003-598X .- 1745-1744. ; 96:390, s. 1628-1633
  • Tidskriftsartikel (refereegranskat)abstract
    • A recent study from Central Europe has changed our perception of the cat's domestication history. The authors discuss how this has led to the development of an interdisciplinary project combining palaeogenetics, zooarchaeologv and radiocarbon dating, with the aim of providing insight into the domestic cat's expansion beyond the Mediterranean.
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  • Horejs, B, et al. (författare)
  • New Multi-disciplinary Data from the Neolithic in Serbia. The 2019 and 2021 Excavations at Svinjarička Čuka
  • 2022
  • Ingår i: Archaeologia Austriaca. - : Osterreichische Akademie der Wissenschaften, Verlag. - 0003-8008 .- 1816-2959. ; 106, s. 255-317
  • Tidskriftsartikel (refereegranskat)abstract
    • The excavations at Svinjarička Čuka in the South Morava Valley in Serbia are presented with new primary data from the field and related material and scientific analyses. Newly recovered architectural remains from the classical Starčevo period revealed a variety of domestic features, so far belonging to an earlier and later occupation phase at the river terrace dating between 5700/5600 and 5500 BC. Details of the stratigraphy and certain materials are presented for selected domestic contexts, including one potential ‘Starčevo house’. Archaeological and scientific analyses are discussed and contextualised within the Neolithisation process in the chapters on new radiocarbon data and their Bayesian modelling, pottery studies, chipped stones and their raw material analyses, grinding kits, animal remains, archaeobotanical results and charcoal analysis. The later occupation at the site is presented with new results for the Middle and Late Bronze Age and the Early Iron Age, including domestic contexts, radiocarbon data and materials.
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  • Milanović, Slobodan, et al. (författare)
  • Relationships between the Pathogen Erysiphe alphitoides, the Phytophagous Mite Schizotetranychus garmani (Acari: Tetranychidae) and the Predatory Mite Euseius finlandicus (Acari: Phytoseiidae) in Oak
  • 2021
  • Ingår i: Insects. - : MDPI AG. - 2075-4450. ; 12:11
  • Tidskriftsartikel (refereegranskat)abstract
    • Food webs on forest trees include plant pathogens, arthropods, and their natural enemies. To increase the understanding of the impact of a plant pathogen on herbivore-natural enemy interactions, we studied the powdery mildew fungus Erysiphe alphitoides, the phytophagous mite Schizotetranychus garmani, and the predatory and mycophagous mite Euseius finlandicus in pedunculate oak (Quercus robur) leaves. In June, July and August of 2016, we assessed the severity of powdery mildew, mite population density and adult female mite size in 30 trees in three forests near Belgrade, Serbia. In August, the infection severity of E. alphitoides related positively to the population density of S. garmani and negatively to the body size of S. garmani females. Throughout the vegetative season, the infection severity of E. alphitoides related positively to the population density of E. finlandicus but not to its body size. The effect of E. alphitoides on the population density and adult size of S. garmani was not mediated by the population density of E. finlandicus, and vice versa. Interactions were consistent in all forests and varied with the summer month. Our findings indicate that E. alphitoides can influence the average body size and population densities of prey and predatory mites studied, irrespective of predator-prey relationships.
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  • Pillai, Rajath S, et al. (författare)
  • Assessment of Somatosensory and Psychosocial Function of Patients With Trigeminal Nerve Damage
  • 2020
  • Ingår i: Clinical Journal of Pain. - : Lippincott Williams & Wilkins. - 1536-5409 .- 0749-8047. ; 36:5, s. 321-335
  • Tidskriftsartikel (refereegranskat)abstract
    • OBJECTIVE: The present study assessed somatosensory changes related to trigeminal nerve damage using extensive evaluation tools and assessed the effect of such damage on the patients' psychosocial status and quality of life compared with healthy participants.METHODS: In 37 patients with intraorally or extraorally presenting trigeminal nerve damage diagnosed as painful or nonpainful posttraumatic trigeminal neuropathy, psychophysical tests like quantitative sensory testing (QST) and qualitative sensory testing and the electrophysiological "nociceptive-specific" blink reflex were performed. The patients and 20 healthy participants completed a set of questionnaires assessing their psychosocial status and quality of life.RESULTS: A loss or gain of somatosensory function was seen in at least 1 QST parameter in >88.9% of the patients. Patients in whom extraoral QST was performed showed an overall loss of somatosensory function, whereas intraoral QST showed a general gain of somatosensory function. Qualitative sensory testing identified a side-to-side difference in the tactile and pinprick stimulation in >77% of the patients. An abnormal "nociceptive-specific" blink reflex response was seen in 42.1% to 71.4% of patients dependent on the trigeminal branch stimulated, though comparisons with healthy reference values showed ambiguous results. Compared with the healthy participants, patients showed higher scores for pain catastrophizing, symptoms of depression and anxiety, limited jaw function, more somatic symptoms, and significantly impaired oral health-related quality of life (all P<0.038).DISCUSSION: The results from the present study showed presence of varied somatosensory abnormalities when assessed using psychophysical and electrophysiological investigations and a significantly impaired psychosocial status.
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  • Zhang, Hong, et al. (författare)
  • Multimodal host-guest complexation for efficient and stable perovskite photovoltaics
  • 2021
  • Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 12:1
  • Tidskriftsartikel (refereegranskat)abstract
    • Formamidinium lead iodide perovskites are promising light-harvesting materials, yet stabilizing them under operating conditions without compromising optimal optoelectronic properties remains challenging. We report a multimodal host-guest complexation strategy to overcome this challenge using a crown ether, dibenzo-21-crown-7, which acts as a vehicle that assembles at the interface and delivers Cs+ ions into the interior while modulating the material. This provides a local gradient of doping at the nanoscale that assists in photoinduced charge separation while passivating surface and bulk defects, stabilizing the perovskite phase through a synergistic effect of the host, guest, and host-guest complex. The resulting solar cells show power conversion efficiencies exceeding 24% and enhanced operational stability, maintaining over 95% of their performance without encapsulation for 500h under continuous operation. Moreover, the host contributes to binding lead ions, reducing their environmental impact. This supramolecular strategy illustrates the broad implications of host-guest chemistry in photovoltaics. It remains a challenge to achieve a balance between performance and stability, as well as addressing the environmental impact of perovskite solar cells. Here, the authors propose a multimodal host-guest complexation strategy enabling these shortcomings to be addressed simultaneously.
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