| 1. |
|
|
| 2. |
- Fantini, R, et al.
(författare)
-
EU FP7 INFSO-ICT-317669 METIS, D3.2 First performance results for multi-node/multi-antenna transmission technologies
- 2014
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This deliverable describes the current results of the multi-node/multi-antenna technologies investigated within METIS and analyses the interactions within and outside Work Package 3. Furthermore, it identifies the most promising technologies based on the current state of obtained results. This document provides a brief overview of the results in its first part. The second part, namely the Appendix, further details the results, describes the simulation alignment efforts conducted in the Work Package and the interaction of the Test Cases. The results described here show that the investigations conducted in Work Package 3 are maturing resulting in valuable innovative solutions for future 5G systems.
|
|
| 3. |
- Carvalho, E. de, et al.
(författare)
-
EU FP7 INFSO-ICT-317669 METIS, D3.1 Positioning of multi-node/multi-antenna technologies
- 2013
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This document describes the research activity in multi-node/multi-antenna technologies within METIS and positions it with respect to the state-of-the-art in the academic literature and in the standardization bodies. Based on the state-of-the-art and as well as on the METIS objectives,we set the research objectives and we group the different activities (or technology components) into research clusters with similar research objectives. The technologycomponents and the research objectives have been set to achieve an ambidextrous purpose. On one side we aim at providing the METIS system with those technological components that are a natural but non-trivial evolution of 4G. On the other side, we aim at seeking for disruptivetechnologies that could radically change 5G with respect to 4G. Moreover, we mapped the different technology components to METIS’ other activities and to the overall goals of theproject.
|
|
| 4. |
|
|
| 5. |
- Oikonomou, Vasileios, et al.
(författare)
-
The Role of Interferon-γ in Autoimmune Polyendocrine Syndrome Type 1.
- 2024
-
Ingår i: The New England journal of medicine. - 1533-4406. ; 390:20, s. 1873-1884
-
Tidskriftsartikel (refereegranskat)abstract
- Autoimmune polyendocrine syndrome type 1 (APS-1) is a life-threatening, autosomal recessive syndrome caused by autoimmune regulator (AIRE) deficiency. In APS-1, self-reactive T cells escape thymic negative selection, infiltrate organs, and drive autoimmune injury. The effector mechanisms governing T-cell-mediated damage in APS-1 remain poorly understood.We examined whether APS-1 could be classified as a disease mediated by interferon-γ. We first assessed patients with APS-1 who were participating in a prospective natural history study and evaluated mRNA and protein expression in blood and tissues. We then examined the pathogenic role of interferon-γ using Aire-/-Ifng-/- mice and Aire-/- mice treated with the Janus kinase (JAK) inhibitor ruxolitinib. On the basis of our findings, we used ruxolitinib to treat five patients with APS-1 and assessed clinical, immunologic, histologic, transcriptional, and autoantibody responses.Patients with APS-1 had enhanced interferon-γ responses in blood and in all examined autoimmunity-affected tissues. Aire-/- mice had selectively increased interferon-γ production by T cells and enhanced interferon-γ, phosphorylated signal transducer and activator of transcription 1 (pSTAT1), and CXCL9 signals in multiple organs. Ifng ablation or ruxolitinib-induced JAK-STAT blockade in Aire-/- mice normalized interferon-γ responses and averted T-cell infiltration and damage in organs. Ruxolitinib treatment of five patients with APS-1 led to decreased levels of T-cell-derived interferon-γ, normalized interferon-γ and CXCL9 levels, and remission of alopecia, oral candidiasis, nail dystrophy, gastritis, enteritis, arthritis, Sjögren's-like syndrome, urticaria, and thyroiditis. No serious adverse effects from ruxolitinib were identified in these patients.Our findings indicate that APS-1, which is caused by AIRE deficiency, is characterized by excessive, multiorgan interferon-γ-mediated responses. JAK inhibition with ruxolitinib in five patients showed promising results. (Funded by the National Institute of Allergy and Infectious Diseases and others.).
|
|
| 6. |
- Osseiran, Afif, et al.
(författare)
-
IoT and machine-type communication
- 2019
-
Ingår i: IEEE Communications Standards Magazine. - : Institute of Electrical and Electronics Engineers (IEEE). - 2471-2825. ; 3:2, s. 44-44
-
Tidskriftsartikel (refereegranskat)abstract
- The two articles in this special section examine the Internet of Things (IoT) and Machine-type communications. IoT is about connecting devices and creating related applications to suit a business and economic need. One of its value propositions is automation. As the industry and academia understand the “plumbing” part of IoT and refine emerging business models such as ones based on software as a service (SaaS) and platform as a service (PaaS), the new developments increasingly focus on: Cross-domain interoperability; data analytics and the emergence of data marketplaces for IoT; and dealing with new application domains in a cost optimized manner, in particular ones that require low latency, high resiliency and availability, and so on.
|
|
| 7. |
|
|
| 8. |
- Osseiran, Afif, et al.
(författare)
-
Future Directions
- 2011
-
Ingår i: Mobile and Wireless Communications for IMT-Advanced and Beyond. - Chichester : John Wiley & Sons. - 9781119993216 ; , s. 251-257
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)
|
|
| 9. |
- Osseiran, Afif, et al.
(författare)
-
Introduction
- 2011
-
Ingår i: Mobile and Wireless Communications for IMT-Advanced and Beyond. - : Wiley. ; , s. 1-9
-
Bokkapitel (refereegranskat)
|
|
