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1.
  • Brown, A. G. A., et al. (författare)
  • Gaia Data Release 1 Summary of the astrometric, photometric, and survey properties
  • 2016
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 595
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. At about 1000 days after the launch of Gaia we present the first Gaia data release, Gaia DR1, consisting of astrometry and photometry for over 1 billion sources brighter than magnitude 20.7. Aims. A summary of Gaia DR1 is presented along with illustrations of the scientific quality of the data, followed by a discussion of the limitations due to the preliminary nature of this release. Methods. The raw data collected by Gaia during the first 14 months of the mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC) and turned into an astrometric and photometric catalogue. Results. Gaia DR1 consists of three components: a primary astrometric data set which contains the positions, parallaxes, and mean proper motions for about 2 million of the brightest stars in common with the HIPPARCOS and Tycho-2 catalogues - a realisation of the Tycho-Gaia Astrometric Solution (TGAS) - and a secondary astrometric data set containing the positions for an additional 1.1 billion sources. The second component is the photometric data set, consisting of mean G-band magnitudes for all sources. The G-band light curves and the characteristics of similar to 3000 Cepheid and RR Lyrae stars, observed at high cadence around the south ecliptic pole, form the third component. For the primary astrometric data set the typical uncertainty is about 0.3 mas for the positions and parallaxes, and about 1 mas yr(-1) for the proper motions. A systematic component of similar to 0.3 mas should be added to the parallax uncertainties. For the subset of similar to 94 000 HIPPARCOS stars in the primary data set, the proper motions are much more precise at about 0.06 mas yr(-1). For the secondary astrometric data set, the typical uncertainty of the positions is similar to 10 mas. The median uncertainties on the mean G-band magnitudes range from the mmag level to similar to 0.03 mag over the magnitude range 5 to 20.7. Conclusions. Gaia DR1 is an important milestone ahead of the next Gaia data release, which will feature five-parameter astrometry for all sources. Extensive validation shows that Gaia DR1 represents a major advance in the mapping of the heavens and the availability of basic stellar data that underpin observational astrophysics. Nevertheless, the very preliminary nature of this first Gaia data release does lead to a number of important limitations to the data quality which should be carefully considered before drawing conclusions from the data.
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2.
  • Prusti, T., et al. (författare)
  • The Gaia mission
  • 2016
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 595
  • Tidskriftsartikel (refereegranskat)abstract
    • Gaia is a cornerstone mission in the science programme of the European Space Agency (ESA). The spacecraft construction was approved in 2006, following a study in which the original interferometric concept was changed to a direct-imaging approach. Both the spacecraft and the payload were built by European industry. The involvement of the scientific community focusses on data processing for which the international Gaia Data Processing and Analysis Consortium (DPAC) was selected in 2007. Gaia was launched on 19 December 2013 and arrived at its operating point, the second Lagrange point of the Sun-Earth-Moon system, a few weeks later. The commissioning of the spacecraft and payload was completed on 19 July 2014. The nominal five-year mission started with four weeks of special, ecliptic-pole scanning and subsequently transferred into full-sky scanning mode. We recall the scientific goals of Gaia and give a description of the as-built spacecraft that is currently (mid-2016) being operated to achieve these goals. We pay special attention to the payload module, the performance of which is closely related to the scientific performance of the mission. We provide a summary of the commissioning activities and findings, followed by a description of the routine operational mode. We summarise scientific performance estimates on the basis of in-orbit operations. Several intermediate Gaia data releases are planned and the data can be retrieved from the Gaia Archive, which is available through the Gaia home page.
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3.
  • van Leeuwen, F., et al. (författare)
  • Gaia Data Release 1 : Open cluster astrometry: Performance, limitations, and future prospects
  • 2017
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 601
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. The first Gaia Data Release contains the Tycho-Gaia Astrometric Solution (TGAS). This is a subset of about 2 million stars for which, besides the position and photometry, the proper motion and parallax are calculated using Hipparcos and Tycho-2 positions in 1991.25 as prior information. Aims. We investigate the scientific potential and limitations of the TGAS component by means of the astrometric data for open clusters. Methods. Mean cluster parallax and proper motion values are derived taking into account the error correlations within the astrometric solutions for individual stars, an estimate of the internal velocity dispersion in the cluster, and, where relevant, the effects of the depth of the cluster along the line of sight. Internal consistency of the TGAS data is assessed. Results. Values given for standard uncertainties are still inaccurate and may lead to unrealistic unit-weight standard deviations of least squares solutions for cluster parameters. Reconstructed mean cluster parallax and proper motion values are generally in very good agreement with earlier Hipparcos-based determination, although the Gaia mean parallax for the Pleiades is a significant exception. We have no current explanation for that discrepancy. Most clusters are observed to extend to nearly 15 pc from the cluster centre, and it will be up to future Gaia releases to establish whether those potential cluster-member stars are still dynamically bound to the clusters. Conclusions. The Gaia DR1 provides the means to examine open clusters far beyond their more easily visible cores, and can provide membership assessments based on proper motions and parallaxes. A combined HR diagram shows the same features as observed before using the Hipparcos data, with clearly increased luminosities for older A and F dwarfs.
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4.
  • Clementini, G., et al. (författare)
  • Testing parallaxes with local Cepheids and RR Lyrae stars
  • 2017
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 605
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. Parallaxes for 331 classical Cepheids, 31 Type II Cepheids, and 364 RR Lyrae stars in common between Gaia and the HIPPARCOS and Tycho-2 catalogues are published in Gaia Data Release 1 (DR1) as part of the Tycho-Gaia Astrometric Solution (TGAS). Aims. In order to test these first parallax measurements of the primary standard candles of the cosmological distance ladder, which involve astrometry collected by Gaia during the initial 14 months of science operation, we compared them with literature estimates and derived new period-luminosity (PL), period-Wesenheit (PW) relations for classical and Type II Cepheids and infrared PL, PL-metallicity (PLZ), and optical luminosity-metallicity (MV-[Fe/H]) relations for the RR Lyrae stars, with zero points based on TGAS.Methods. Classical Cepheids were carefully selected in order to discard known or suspected binary systems. The final sample comprises 102 fundamental mode pulsators with periods ranging from 1.68 to 51.66 days (of which 33 with sigma(omega)/omega < 0 : 5). The Type II Cepheids include a total of 26 W Virginis and BL Herculis stars spanning the period range from 1.16 to 30.00 days (of which only 7 with sigma(omega)/omega 0 : 5). The RR Lyrae stars include 200 sources with pulsation period ranging from 0.27 to 0.80 days (of which 112 with sigma(omega)/omega < 0 : 5). The new relations were computed using multi- band (V; I; J; K-s) photometry and spectroscopic metal abundances available in the literature, and by applying three alternative approaches: (i) linear least-squares fitting of the absolute magnitudes inferred from direct transformation of the TGAS parallaxes; (ii) adopting astrometry-based luminosities; and (iii) using a Bayesian fitting approach. The last two methods work in parallax space where parallaxes are used directly, thus maintaining symmetrical errors and allowing negative parallaxes to be used. The TGAS-based PL; PW; PLZ, and MV [Fe/H] relations are discussed by comparing the distance to the Large Magellanic Cloud provided by different types of pulsating stars and alternative fitting methods.Results. Good agreement is found from direct comparison of the parallaxes of RR Lyrae stars for which both TGAS and HST measurements are available. Similarly, very good agreement is found between the TGAS values and the parallaxes inferred from the absolute magnitudes of Cepheids and RR Lyrae stars analysed with the Baade-Wesselink method. TGAS values also compare favourably with the parallaxes inferred by theoretical model fitting of the multi-band light curves for two of the three classical Cepheids and one RR Lyrae star, which were analysed with this technique in our samples. The K-band PL relations show the significant improvement of the TGAS parallaxes for Cepheids and RR Lyrae stars with respect to the HIPPARCOS measurements. This is particularly true for the RR Lyrae stars for which improvement in quality and statistics is impressive.Conclusions. TGAS parallaxes bring a significant added value to the previous HIPPARCOS estimates. The relations presented in this paper represent the first Gaia-calibrated relations and form a work-in-progress milestone report in the wait for Gaia-only parallaxes of which a first solution will become available with Gaia Data Release 2 (DR2) in 2018.
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5.
  • Smiljanic, R., et al. (författare)
  • The Gaia-ESO Survey: The analysis of high-resolution UVES spectra of FGK-type stars
  • 2014
  • Ingår i: Astronomy & Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 570
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. The ongoing Gaia-ESO Public Spectroscopic Survey is using FLAMES at the VLT to obtain high-quality medium-resolution Giraffe spectra for about 10(5) stars and high-resolution UVES spectra for about 5000 stars. With UVES, the Survey has already observed 1447 FGK-type stars. Aims. These UVES spectra are analyzed in parallel by several state-of-the-art methodologies. Our aim is to present how these analyses were implemented, to discuss their results, and to describe how a final recommended parameter scale is defined. We also discuss the precision (method-to-method dispersion) and accuracy (biases with respect to the reference values) of the final parameters. These results are part of the Gaia-ESO second internal release and will be part of its first public release of advanced data products. Methods. The final parameter scale is tied to the scale defined by the Gaia benchmark stars, a set of stars with fundamental atmospheric parameters. In addition, a set of open and globular clusters is used to evaluate the physical soundness of the results. Each of the implemented methodologies is judged against the benchmark stars to define weights in three different regions of the parameter space. The final recommended results are the weighted medians of those from the individual methods. Results. The recommended results successfully reproduce the atmospheric parameters of the benchmark stars and the expected T-eff-log g relation of the calibrating clusters. Atmospheric parameters and abundances have been determined for 1301 FGK-type stars observed with UVES. The median of the method-to-method dispersion of the atmospheric parameters is 55K for T-eff, 0.13dex for log g and 0.07 dex for [Fe/H]. Systematic biases are estimated to be between 50-100 K for T-eff, 0.10-0.25 dex for log g and 0.05-0.10 dex for [Fe/H]. Abundances for 24 elements were derived: C, N, O, Na, Mg, Al, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Mo, Ba, Nd, and Eu. The typical method-to-method dispersion of the abundances varies between 0.10 and 0.20 dex. Conclusions. The Gaia-ESO sample of high-resolution spectra of FGK-type stars will be among the largest of its kind analyzed in a homogeneous way. The extensive list of elemental abundances derived in these stars will enable significant advances in the areas of stellar evolution and Milky Way formation and evolution.
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10.
  • Lind, Karin, et al. (författare)
  • The Gaia-ESO Survey : A globular cluster escapee in the Galactic halo
  • 2015
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 575
  • Tidskriftsartikel (refereegranskat)abstract
    • A small fraction of the halo field is made up of stars that share the light element (Z <= 13) anomalies characteristic of second generation globular cluster (GC) stars. The ejected stars shed light on the formation of the Galactic halo by tracing the dynamical history of the clusters, which are believed to have once been more massive. Some of these ejected stars are expected to show strong Al enhancement at the expense of shortage of Mg, but until now no such star has been found. We search for outliers in the Mg and Al abundances of the few hundreds of halo field stars observed in the first eighteen months of the Gaia-ESO public spectroscopic survey. One halo star at the base of the red giant branch, here referred to as 22593757-4648029 is found to have [Mg/Fe] = -0.36 +/- 0.04 and [Al/Fe] = 0.99 +/- 0.08, which is compatible with the most extreme ratios detected in GCs so far. We compare the orbit of 22593757-4648029 to GCs of similar metallicity and find it unlikely that this star has been tidally stripped with low ejection velocity from any of the clusters. However, both chemical and kinematic arguments render it plausible that the star has been ejected at high velocity from the anomalous GC omega Centauri within the last few billion years. We cannot rule out other progenitor GCs, because some may have disrupted fully, and the abundance and orbital data are inadequate for many of those that are still intact.
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14.
  • Amarsi, Anish, et al. (författare)
  • The GALAH Survey : non-LTE departure coefficients for large spectroscopic surveys
  • 2020
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 642
  • Tidskriftsartikel (refereegranskat)abstract
    • Massive sets of stellar spectroscopic observations are rapidly becoming available and these can be used to determine the chemical composition and evolution of the Galaxy with unprecedented precision. One of the major challenges in this endeavour involves constructing realistic models of stellar spectra with which to reliably determine stellar abundances. At present, large stellar surveys commonly use simplified models that assume that the stellar atmospheres are approximately in local thermodynamic equilibrium (LTE). To test and ultimately relax this assumption, we have performed non-LTE calculations for 13 different elements (H, Li, C, N, O, Na, Mg, Al, Si, K, Ca, Mn, and Ba), using recent model atoms that have physically-motivated descriptions for the inelastic collisions with neutral hydrogen, across a grid of 3756 1D MARCS model atmospheres that spans 3000 <= T-eff/K <= 8000, - 0.5 <= log g/cm s(-2) <= 5.5, and - 5 <= [Fe/H] <= 1. We present the grids of departure coefficients that have been implemented into the GALAH DR3 analysis pipeline in order to complement the extant non-LTE grid for iron. We also present a detailed line-by-line re-analysis of 50 126 stars from GALAH DR3. We found that relaxing LTE can change the abundances by between - 0.7 dex and + 0.2 dex for different lines and stars. Taking departures from LTE into account can reduce the dispersion in the [A/Fe] versus [Fe/H] plane by up to 0.1 dex, and it can remove spurious differences between the dwarfs and giants by up to 0.2 dex. The resulting abundance slopes can thus be qualitatively different in non-LTE, possibly with important implications for the chemical evolution of our Galaxy. The grids of departure coefficients are publicly available and can be implemented into LTE pipelines to make the most of observational data sets from large spectroscopic surveys.
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15.
  • Buder, S., et al. (författare)
  • The GALAH survey : An abundance, age, and kinematic inventory of the solar neighbourhood made with TGAS
  • 2019
  • Ingår i: Astronomy and Astrophysics. - : EDP SCIENCES S A. - 0004-6361 .- 1432-0746. ; 624
  • Tidskriftsartikel (refereegranskat)abstract
    • The overlap between the spectroscopic Galactic Archaeology with HERMES (GALAH) survey and Gaia provides a high-dimensional chemodynamical space of unprecedented size. We present a first analysis of a subset of this overlap, of 7066 dwarf, turn-off, and subgiant stars. These stars have spectra from the GALAH survey and high parallax precision from the Gaia DR1 Tycho-Gaia Astrometric Solution. We investigate correlations between chemical compositions, ages, and kinematics for this sample. Stellar parameters and elemental abundances are derived from the GALAH spectra with the spectral synthesis code SPECTROSCOPY MADE EASY. We determine kinematics and dynamics, including action angles, from the Gaia astrometry and GALAH radial velocities. Stellar masses and ages are determined with Bayesian isochrone matching, using our derived stellar parameters and absolute magnitudes. We report measurements of Li, C, O, Na, Mg, Al, Si, K, Ca, Sc, Ti, V, Cr, Mn, Co, Ni, Cu, Zn, Y, as well as Ba and we note that we have employed non-LTE calculations for Li, O, Al, and Fe. We show that the use of astrometric and photometric data improves the accuracy of the derived spectroscopic parameters, especially log g. Focusing our investigation on the correlations between stellar age, iron abundance [Fe/H], and mean alpha-enhancement [alpha/Fe] of the magnitude-selected sample, we recover the result that stars of the high-a sequence are typically older than stars in the low-a sequence, the latter spanning iron abundances of -0.7 < [Fe/H] < +0.5. While these two sequences become indistinguishable in [alpha/Fe] vs. [Fe/H] at the metal-rich regime, we find that age can be used to separate stars from the extended high-a and the low-a sequence even in this regime. When dissecting the sample by stellar age, we find that the old stars (>8 Gyr) have lower angular momenta L-z than the Sun, which implies that they are on eccentric orbits and originate from the inner disc. Contrary to some previous smaller scale studies we find a continuous evolution in the high-alpha-sequence up to super-solar [Fe/H] rather than a gap, which has been interpreted as a separate "high-alpha metal-rich" population. Stars in our sample that are younger than 10 Gyr, are mainly found on the low alpha-sequence and show a gradient in L-z from low [Fe/H] > (L-z > L-z,L-circle dot) towards higher [Fe/H] (L-z < L-z,L-circle dot), which implies that the stars at the ends of this sequence are likely not originating from the close solar vicinity.
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16.
  • Cattaneo, C, et al. (författare)
  • Simultaneous Onset of Haematological Malignancy and COVID: An Epicovideha Survey
  • 2022
  • Ingår i: Cancers. - : MDPI AG. - 2072-6694. ; 14:22
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The outcome of patients with simultaneous diagnosis of haematological malignancies (HM) and COVID-19 is unknown and there are no specific treatment guidelines. Methods: We describe the clinical features and outcome of a cohort of 450 patients with simultaneous diagnosis of HM and COVID-19 registered in the EPICOVIDEHA registry between March 2020 to February 2022. Results: Acute leukaemia and lymphoma were the most frequent HM (35.8% and 35.1%, respectively). Overall, 343 (76.2%) patients received treatment for HM, which was delayed for longer than one month since diagnosis in 57 (16.6%). An overall response rate was observed in 140 (40.8%) patients after the first line of treatment. After a median follow-up of 35 days, overall mortality was 177/450 (39.3%); 30-day mortality was significantly higher in patients not receiving HM treatment (42.1%) than in those receiving treatment (27.4%, p = 0.004), either before and/or after COVID-19, or compared to patients receiving HM treatment at least after COVID-19 (15.2%, p < 0.001). Age, severe/critical COVID-19, ≥2 comorbidities, and lack of HM treatment were independent risk factors for mortality, whereas a lymphocyte count >500/mcl at COVID-19 onset was protective. Conclusions: HM treatment should be delivered as soon as possible for patients with simultaneous diagnosis of COVID-19 and HM requiring immediate therapy.
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17.
  • Cordoni, G., et al. (författare)
  • Exploring the Galaxy's halo and very metal-weak thick disc with SkyMapper and Gaia DR2
  • 2021
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 503:2, s. 2539-2561
  • Tidskriftsartikel (refereegranskat)abstract
    • In this work, we combine spectroscopic information from the SkyMapper survey for Extremely Metal-Poor stars and astrometry from Gaia DR2 to investigate the kinematics of a sample of 475 stars with a metallicity range of -6.5 <= [Fe/H] <= -2.05 dex. Exploiting the action map, we identify 16 and 40 stars dynamically consistent with the Gaia Sausage and Gaia Sequoia accretion events, respectively. The most metal poor of these candidates have metallicities of [Fe/H] = - 3.31 and - 3.74, respectively, helping to define the low-metallicity tail of the progenitors involved in the accretion events. We also find, consistent with other studies, that similar to 21 per cent of the sample have orbits that remain confined to within 3 kpc of the Galactic plane, that is, |Z(max)| <= 3 kpc. Of particular interest is a subsample (similar to 11 per cent of the total) of low |Z(max)| stars with low eccentricities and prograde motions. The lowest metallicity of these stars has [Fe/H] = -4.30 and the subsample is best interpreted as the very low-metallicity tail of the metal-weak thick disc population. The low |Z(max)|, low eccentricity stars with retrograde orbits are likely accreted, while the low |Z(max)|, high eccentricity pro- and retrograde stars are plausibly associated with the Gaia Sausage system. We find that a small fraction of our sample (similar to 4 per cent of the total) is likely escaping from the Galaxy, and postulate that these stars have gained energy from gravitational interactions that occur when infalling dwarf galaxies are tidally disrupted.
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  • Jofré, P., et al. (författare)
  • Gaia FGK benchmark stars : abundances of α and iron-peak elements
  • 2015
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 582
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. In the current era of large spectroscopic surveys of the Milky Way, reference stars for calibrating astrophysical parameters and chemical abundances are of paramount importance. Aims. We determine elemental abundances of Mg, Si, Ca, Sc, Ti, V, Cr, Mn, Co, and Ni for our predefined set of Gaia FGK benchmark stars. Methods. By analysing high-resolution spectra with a high signal-to-noise ratio taken from several archive datasets, we combined results of eight different methods to determine abundances on a line-by-line basis. We performed a detailed homogeneous analysis of the systematic uncertainties, such as differential versus absolute abundance analysis. We also assessed errors that are due to non-local thermal equilibrium and the stellar parameters in our final abundances. Results. Our results are provided by listing final abundances and the different sources of uncertainties, as well as line-by-line and method-by-method abundances. Conclusions. The atmospheric parameters of the Gaia FGK benchmark stars are already being widely used for calibration of several pipelines that are applied to different surveys. With the added reference abundances of ten elements, this set is very suitable for calibrating the chemical abundances obtained by these pipelines.
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  • Marino, A. F., et al. (författare)
  • Keck HIRES spectroscopy of SkyMapper commissioning survey candidate extremely metal-poor stars
  • 2019
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : OXFORD UNIV PRESS. - 0035-8711 .- 1365-2966. ; 485:4, s. 5153-5167
  • Tidskriftsartikel (refereegranskat)abstract
    • We present results from the analysis of high-resolution spectra obtained with the Keck HIRES spectrograph for a sample of 17 candidate extremely metal-poor (EMP) stars originally selected from commissioning data obtained with the SkyMapper telescope. Fourteen of the stars have not been observed previously at high dispersion. Three have [Fe/H] <= -3.0, while the remainder, with two more metal-rich exceptions, have -3.0 <= [Fe/H] <= -2.0 dex. Apart from Fe, we also derive abundances for the elements C, N, Na, Mg, Al, Si, Ca, Sc, Ti, Cr, Mn, Co, Ni, and Zn, and for n-capture elements Sr, Ba, and Eu. None of the current sample of stars is found to be carbon-rich. In general, our chemical abundances follow previous trends found in the literature, although we note that two of the most metal-poor stars show very low [Ba/Fe] (similar to-1.7) coupled with low [Sr/Ba] (similar to-0.3). Such stars are relatively rare in the Galactic halo. One further star, and possibly two others, meet the criteria for classification as a r-I star. This study, together with that of Jacobson et al. (2015), completes the outcomes of the SkyMapper commissioning data survey for EMP stars.
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  • Smiljanic, R., et al. (författare)
  • The Gaia-ESO Survey : Sodium and aluminium abundances in giants and dwarfs Implications for stellar and Galactic chemical evolution
  • 2016
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 589
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. Stellar evolution models predict that internal mixing should cause some sodium overabundance at the surface of red giants more massive than similar to 1.5-2.0 M-circle dot. The surface aluminium abundance should not be affected. Nevertheless, observational results disagree about the presence and/or the degree of Na and Al overabundances. In addition, Galactic chemical evolution models adopting different stellar yields lead to very different predictions for the behavior of [Na/Fe] and [Al/Fe] versus [Fe/H]. Overall, the observed trends of these abundances with metallicity are not well reproduced.Aims. We readdress both issues, using new Na and Al abundances determined within the Gaia-ESO Survey. Our aim is to obtain better observational constraints on the behavior of these elements using two samples: i) more than 600 dwarfs of the solar neighborhood and of open clusters and ii) low-and intermediate-mass clump giants in six open clusters.Methods. Abundances were determined using high-resolution UVES spectra. The individual Na abundances were corrected for nonlocal thermodynamic equilibrium effects. For the Al abundances, the order of magnitude of the corrections was estimated for a few representative cases. For giants, the abundance trends with stellar mass are compared to stellar evolution models. For dwarfs, the abundance trends with metallicity and age are compared to detailed chemical evolution models.Results. Abundances of Na in stars with mass below similar to 2.0 M-circle dot, and of Al in stars below similar to 3.0 M-circle dot, seem to be unaffected by internal mixing processes. For more massive stars, the Na overabundance increases with stellar mass. This trend agrees well with predictions of stellar evolutionary models. For Al, our only cluster with giants more massive than 3.0 M-circle dot, NGC 6705, is Al enriched. However, this might be related to the environment where the cluster was formed. Chemical evolution models that well fit the observed [Na/Fe] vs. [Fe/H] trend in solar neighborhood dwarfs cannot simultaneously explain the run of [Al/Fe] with [Fe/H], and vice versa. The comparison with stellar ages is hampered by severe uncertainties. Indeed, reliable age estimates are available for only a half of the stars of the sample. We conclude that Al is underproduced by the models, except for stellar ages younger than about 7 Gyr. In addition, some significant source of late Na production seems to be missing in the models. Either current Na and Al yields are affected by large uncertainties, and/or some important Galactic source(s) of these elements has as yet not been taken into account.
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  • Spina, L., et al. (författare)
  • The GALAH survey : tracing the Galactic disc with open clusters
  • 2021
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 503:3, s. 3279-3296
  • Tidskriftsartikel (refereegranskat)abstract
    • Open clusters are unique tracers of the history of our own Galaxy's disc. According to our membership analysis based on Gala astrometry, out of the 226 potential clusters falling in the footprint of the GALactic Archaeology with HERMES (GALAH) survey or the Apache Point Observatory Galactic Evolution Experiment (APOGEE) survey, we find that 205 have secure members that were observed by at least one of the surveys. Furthermore, members of 134 clusters have high-quality spectroscopic data that we use to determine their chemical composition. We leverage this information to study the chemical distribution throughout the Galactic disc of 21 elements, from C to Eu. The radial metallicity gradient obtained from our analysis is -0.076 +/- 0.009 dex kpc(-1), which is in agreement with previous works based on smaller samples. Furthermore, the gradient in the (Fe/Hi-guiding radius (r(guid)) plane is -0.073 +/- 0.008 dex kpc(-1). We show consistently that open clusters trace the distribution of chemical elements throughout the Galactic disc differently than field stars. In particular, at the given radius, open clusters show an age-metallicity relation that has less scatter than field stars. As such scatter is often interpreted as an effect of radial migration, we suggest that these differences are due to the physical selection effect imposed by our Galaxy: clusters that would have migrated significantly also had higher chances to get destroyed. Finally, our results reveal trends in the [X/Fe]-r(guid)-age space, which are important to understand production rates of different elements as a function of space and time.
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  • Da Costa, G. S., et al. (författare)
  • The SkyMapper DR1.1 search for extremely metal-poor stars
  • 2019
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : OXFORD UNIV PRESS. - 0035-8711 .- 1365-2966. ; 489:4, s. 5900-5918
  • Tidskriftsartikel (refereegranskat)abstract
    • We present and discuss the results of a search for extremely metal-poor stars based on photometry from data release DR1.1 of the SkyMapper imaging survey of the southern sky. In particular, we outline our photometric selection procedures and describe the low-resolution (R approximate to 3000) spectroscopic follow-up observations that are used to provide estimates of effective temperature, surface gravity, and metallicity ([Fe/H]) for the candidates. The selection process is very efficient: of the 2618 candidates with low-resolution spectra that have photometric metallicity estimates less than or equal to -2.0, 41 per cent have [Fe/H] <= -2.75 and only approximately seven per cent have [Fe/H] > -2.0 dex. The most metal-poor candidate in the sample has [Fe/H] < -4.75 and is notably carbon rich. Except at the lowest metallicities ([Fe/H] < -4), the stars observed spectroscopically are dominated by a 'carbon-normal' population with [C/Fe](1D, LTE) <= +1 dex. Consideration of the A(C)(1D, LTE) versus [Fe/H](1D, LTE) diagram suggests that the current selection process is strongly biased against stars with A(C)(1D, LTE) > 7.3 (predominantly CEMP-s) while any bias against stars with A(C)(1D, LTE) < 7.3 and [C/Fe](1D, LTE) > +1 (predominantly CEMP-no) is not readily quantifiable given the uncertainty in the SkyMapper v-band DR1.1 photometry. We find that the metallicity distribution function of the observed sample has a power-law slope of Delta(Log N)/Delta[Fe/H] = 1.5 +/- 0.1 dex per dex for -4.0 <= [Fe/H] <= -2.75, but appears to drop abruptly at [Fe/H] approximate to -4.2, in line with previous studies.
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25.
  • Jofre, P., et al. (författare)
  • Gaia FGK benchmark stars : Metallicity
  • 2014
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 564, s. A133-
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. To calibrate automatic pipelines that determine atmospheric parameters of stars, one needs a sample of stars, or "benchmark stars", with well-defined parameters to be used as a reference. Aims. We provide detailed documentation of the iron abundance determination of the 34 FGK-type benchmark stars that are selected to be the pillars for calibration of the one billion Gaia stars. They cover a wide range of temperatures, surface gravities, and metallicities. Methods. Up to seven different methods were used to analyze an observed spectral library of high resolutions and high signal-to-noise ratios. The metallicity was determined by assuming a value of effective temperature and surface gravity obtained from fundamental relations; that is, these parameters were known a priori and independently from the spectra. Results. We present a set of metallicity values obtained in a homogeneous way for our sample of benchmark stars. In addition to this value, we provide detailed documentation of the associated uncertainties.Finally, we report a value of the metallicity of the cool giant psi Phe for the first time.
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26.
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27.
  • Marchetti, M, et al. (författare)
  • Outcomes of SARS-CoV-2 infection in Ph-neg chronic myeloproliferative neoplasms: results from the EPICOVIDEHA registry
  • 2023
  • Ingår i: Therapeutic advances in hematology. - : SAGE Publications. - 2040-6207 .- 2040-6215. ; 14, s. 20406207231154706-
  • Tidskriftsartikel (refereegranskat)abstract
    • Patients with Philadelphia-negative chronic myeloproliferative neoplasms (MPN) typically incur high rates of infections and both drugs and comorbidities may modulate infection risk. Objectives: The present study aims to assess the effect of immunosuppressive agents on clinical outcomes of MPN patients affected by the coronavirus disease 2019 (COVID-19). Design: This is an observational study. Methods: We specifically searched and analyzed MPN patients collected by EPICOVIDEHA online registry, which includes individuals with hematological malignancies diagnosed with COVID-19 since February 2020. Results: Overall, 398 patients with MPN were observed for a median of 76 days [interquartile range (IQR): 19–197] after detection of SARS-CoV2 infection. Median age was 69 years (IQR: 58–77) and 183 individuals (46%) had myelofibrosis (MF). Overall, 121 patients (30%) of the whole cohort received immunosuppressive therapies including steroids, immunomodulatory drugs, or JAK inhibitors. Hospitalization and consecutive admission to intensive care unit was required in 216 (54%) and 53 patients (13%), respectively. Risk factors for hospital admission were identified by multivariable logistic regression and include exposure to immunosuppressive therapies [odds ratio (OR): 2.186; 95% confidence interval (CI): 1.357–3.519], age ⩾70 years, and comorbidities. The fatality rate was 22% overall and the risk of death was independently increased by age ⩾70 years [hazard ratio (HR): 2.191; 95% CI: 1.363–3.521], previous comorbidities, and exposure to immunosuppressive therapies before the infection (HR: 2.143; 95% CI: 1.363–3.521). Conclusion: COVID-19 infection led to a particularly dismal outcome in MPN patients receiving immunosuppressive agents or reporting multiple comorbidities. Therefore, specific preventive strategies need to be tailored for such individuals. Plain language summary EPICOVIDEHA registry reports inferior outcomes of COVID-19 in patients with Philadelphia-negative chronic myeloproliferative neoplasms receiving immunosuppressive therapies. Patients with Philadelphia-negative chronic myeloproliferative neoplasms (MPN) incur high rates of infections during the course of their disease. The present study was aimed at assessing which patient characteristics predicted a worse outcome of SARS-COV-2 infection in individuals with MPN. To pursue this objective, the researchers analyzed the data collected by EPICOVIDEHA, an international online registry, which includes individuals with hematological malignancies diagnosed with COVID-19 since February 2020. The database provided clinical data of 398 patients with MPN incurring COVID-19: Patients were mostly elderly (median age was 69 years); Forty-six percent of them were affected by myelofibrosis, which is the most severe MPN; Moreover, 32% were receiving immunosuppressive therapies (JAK inhibitors, such as ruxolitinib, steroids, or immunomodulatory IMID drugs, such as thalidomide) before COVID-19. Hospitalization was required in 54% of the patients, and the risk of being hospitalized for severe COVID-19 was independently predicted by Older age; Comorbidities; Exposure to immunosuppressive therapies. Overall, 22% of MPN patients deceased soon after COVID-19 and the risk of death was independently increased over twofold by Older age; Comorbidities; Exposure to immunosuppressive therapies before the infection. In conclusion, COVID-19 infection led to a particularly dismal outcome in MPN patients receiving immunosuppressive agents, including JAK inhibitors, or reporting multiple comorbidities. Therefore, specific preventive strategies need to be tailored for such individuals.
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28.
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29.
  • Nordlander, T., et al. (författare)
  • The lowest detected stellar Fe abundance : the halo star SMSS J160540.18-144323.1
  • 2019
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : OXFORD UNIV PRESS. - 0035-8711 .- 1365-2966 .- 1745-3925 .- 1745-3933. ; 488:1, s. L109-L113
  • Tidskriftsartikel (refereegranskat)abstract
    • We report the discovery of SMSS J160540.18-144323.1, a new ultra metal-poor halo star discovered with the SkyMapper telescope. We measure [Fe/H] = -6.2 +/- 0.2 (1D LTE), the lowest ever detected abundance of iron in a star. The star is strongly carbon-enhanced, [C/Fe] = 3.9 +/- 0.2, while other abundances are compatible with an alpha-enhanced solar-like pattern with [Ca/Fe] = 0.4 +/- 0.2, [Mg/Fe] = 0.6 +/- 0.2, [Ti/Fe] = 0.8 +/- 0.2, and no significant s- or r-process enrichment, [Sr/Fe] < 0.2 and [Ba/Fe] < 1.0 (3 sigma limits). Population III stars exploding as fallback supernovae may explain both the strong carbon enhancement and the apparent lack of enhancement of odd-Z and neutron-capture element abundances. Grids of supernova models computed for metal-free progenitor stars yield good matches for stars of about 10 M circle dot imparting a low kinetic energy on the supernova ejecta, while models for stars more massive than roughly 20 M circle dot are incompatible with the observed abundance pattern.
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30.
  • Pelaz, B, et al. (författare)
  • Diverse Applications of Nanomedicine
  • 2017
  • Ingår i: ACS nano. - : American Chemical Society (ACS). - 1936-086X .- 1936-0851. ; 11:3, s. 2313-2381
  • Tidskriftsartikel (refereegranskat)
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31.
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32.
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33.
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34.
  • Schulman, S., et al. (författare)
  • Post-thrombotic syndrome, recurrence, and death 10 years after the first episode of venous thromboembolism treated with warfarin for 6 weeks or 6 months
  • 2006
  • Ingår i: Journal of Thrombosis and Haemostasis. - : Elsevier BV. - 1538-7933 .- 1538-7836. ; 4:4, s. 734-742
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: The influence of the duration of anticoagulant therapy after venous thromboembolism (VTE) on the long-term morbidity and mortality is unclear. Aim: To investigate the long-term sequelae of VTE in patients randomized to different duration of secondary prophylaxis. Methods: In a multicenter trial comparing secondary prophylaxis with vitamin K antagonists for 6 weeks or 6 months, we extended the originally planned 2 years follow-up to 10 years. The patients had annual visits and at the last visit clinical assessment of the post-thrombotic syndrome (PTS) was performed. Recurrent thromboembolism was adjudicated by a radiologist, blinded to treatment allocation. Causes of death were obtained from the Swedish Death Registry. Results: Of the 897 patients randomized, 545 could be evaluated at the 10 years follow-up. The probability of developing severe PTS was 6% and any sign of PTS was seen in 56.3% of the evaluated patients. In multivariate analysis, old age and signs of impaired circulation at discharge from the hospital were independent risk factors at baseline for development of PTS after 10 years. Recurrent thromboembolism occurred in 29.1% of the patients with a higher rate among males, older patients, those with permanent gering risk factor - especially with venous insufficiency at baseline - signs of impaired venous circulation at discharge, proximal deep vein thrombosis, or pulmonary embolism. Death occurred in 28.5%, which was a higher mortality than expected with a standardized incidence ratio (SIR) of 1.43 (95% CI 1.28-1.58), mainly because of a higher mortality than expected from cancer (SIR 1.83, 95% CI 1.44-2.23) or from myocardial infarction or stroke (SIR 1.28, 95% CI 1.00-1.56).The duration of anticoagulation did not have a statistically significant effect on any of the long-term outcomes. Conclusion: The morbidity and mortality during 10 years after the first episode of VTE is high and not reduced by extension of secondary prophylaxis from 6 weeks to 6 months. A strategy to reduce recurrence of VTE as well as mortality from arterial disease is needed. © 2006 International Society on Thrombosis and Haemostasis.
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35.
  • Yong, D., et al. (författare)
  • High-resolution spectroscopic follow-up of the most metal-poor candidates from SkyMapper DR1.1
  • 2021
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 507:3, s. 4102-4119
  • Tidskriftsartikel (refereegranskat)abstract
    • We present chemical abundances for 21 elements (from Li to Eu) in 150 metal-poor Galactic stars spanning −4.1 < [Fe/H] < −2.1. The targets were selected from the SkyMapper survey and include 90 objects with [Fe/H] ≤ −3 of which some 15 have [Fe/H] ≤ −3.5. When combining the sample with our previous studies, we find that the metallicity distribution function has a power-law slope of Δ(log N)/Δ[Fe/H] = 1.51 ± 0.01 dex per dex over the range −4 ≤ [Fe/H] ≤ −3. With only seven carbon-enhanced metal-poor stars in the sample, we again find that the selection of metal-poor stars based on SkyMapper filters is biased against highly carbon-rich stars for [Fe/H] > −3.5. Of the 20 objects for which we could measure nitrogen, 11 are nitrogen-enhanced metal-poor (NEMP) stars. Within our sample, the high NEMP fraction (55 per cent ± 21 per cent) is compatible with the upper range of predicted values (between 12 per cent and 35 per cent). The chemical abundance ratios [X/Fe] versus [Fe/H] exhibit similar trends to previous studies of metal-poor stars and Galactic chemical evolution models. We report the discovery of nine new r-I stars, four new r-II stars, one of which is the most metal-poor known, nine low-α stars with [α/Fe] ≤ 0.15 as well as one unusual star with [Zn/Fe] = +1.4 and [Sr/Fe] = +1.2 but with normal [Ba/Fe]. Finally, we combine our sample with literature data to provide the most extensive view of the early chemical enrichment of the Milky Way Galaxy.
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36.
  • Yong, D., et al. (författare)
  • r-Process elements from magnetorotational hypernovae
  • 2021
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 595:7866, s. 223-226
  • Tidskriftsartikel (refereegranskat)abstract
    • Neutron-star mergers were recently confirmed as sites of rapid-neutron-capture (r-process) nucleosynthesis(1-3). However, in Galactic chemical evolution models, neutron-star mergers alone cannot reproduce the observed element abundance patterns of extremely metal-poor stars, which indicates the existence of other sites of r-process nucleosynthesis(4-6). These sites may be investigated by studying the element abundance patterns of chemically primitive stars in the halo of the Milky Way, because these objects retain the nucleosynthetic signatures of the earliest generation of stars(7-13). Here we report the element abundance pattern of the extremely metal-poor star SMSS J200322.54-114203.3. We observe a large enhancement in r-process elements, with very low overall metallicity. The element abundance pattern is well matched by the yields of a single 25-solar-mass magnetorotational hypernova. Such a hypernova could produce not only the r-process elements, but also light elements during stellar evolution, and iron-peak elements during explosive nuclear burning. Hypernovae are often associated with long-duration gamma-ray bursts in the nearby Universe(8). This connection indicates that similar explosions of fast-spinning strongly magnetized stars occurred during the earliest epochs of star formation in our Galaxy.
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37.
  • Bergemann, M., et al. (författare)
  • The Gaia-ESO Survey : radial metallicity gradients and age-metallicity relation of stars in the Milky Way disk
  • 2014
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 565, s. A89-
  • Tidskriftsartikel (refereegranskat)abstract
    • We study the relationship between age, metallicity, and alpha-enhancement of FGK stars in the Galactic disk. The results are based upon the analysis of high-resolution UVES spectra from the Gaia-ESO large stellar survey. We explore the limitations of the observed dataset, i.e. the accuracy of stellar parameters and the selection effects that are caused by the photometric target preselection. We find that the colour and magnitude cuts in the survey suppress old metal-rich stars and young metal-poor stars. This suppression may be as high as 97% in some regions of the age-metallicity relationship. The dataset consists of 144 stars with a wide range of ages from 0.5 Gyr to 13.5 Gyr, Galactocentric distances from 6 kpc to 9.5 kpc, and vertical distances from the plane 0 < vertical bar Z vertical bar < 1.5 kpc. On this basis, we find that i) the observed age-metallicity relation is nearly flat in the range of ages between 0 Gyr and 8 Gyr; ii) at ages older than 9 Gyr, we see a decrease in [Fe/H] and a clear absence of metal-rich stars; this cannot be explained by the survey selection functions; iii) there is a significant scatter of [Fe/H] at any age; and iv) [Mg/Fe] increases with age, but the dispersion of [Mg/Fe] at ages > 9 Gyr is not as small as advocated by some other studies. In agreement with earlier work, we find that radial abundance gradients change as a function of vertical distance from the plane. The [Mg/Fe] gradient steepens and becomes negative. In addition, we show that the inner disk is not only more alpha-rich compared to the outer disk, but also older, as traced independently by the ages and Mg abundances of stars.
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38.
  • Busca, A, et al. (författare)
  • Outcome of COVID-19 in allogeneic stem cell transplant recipients: Results from the EPICOVIDEHA registry
  • 2023
  • Ingår i: Frontiers in immunology. - : Frontiers Media SA. - 1664-3224. ; 14, s. 1125030-
  • Tidskriftsartikel (refereegranskat)abstract
    • The outcome of COVID-19 in allogeneic hematopoietic stem cell transplantation (HSCT) recipients is almost uniformely considered poor. The aim of present study was to retrospectively analyse the outcome and risk factors for mortality in a large series of patients who developed COVID-19 infection after an allogeneic HSCT.MethodsThis multicenter retrospective study promoted by the European Hematology Association – Infections in Hematology Study Working Group, included 326 adult HSCT patients who had COVID-19 between January 2020 and March 2022.ResultsThe median time from HSCT to the diagnosis of COVID-19 was 268 days (IQR 86-713; range 0-185 days). COVID-19 severity was mild in 21% of the patients, severe in 39% and critical in 16% of the patients. In multivariable analysis factors associated with a higher risk of mortality were, age above 50 years, presence of 3 or more comorbidities, active hematologic disease at time of COVID-19 infection, development of COVID-19 within 12 months of HSCT, and severe/critical infections. Overall mortality rate was 21% (n=68): COVID-19 was the main or secondary cause of death in 16% of the patients (n=53).ConclusionsMortality in HSCT recipients who develop COVID-19 is high and largely dependent on age, comorbidities, active hematologic disease, timing from transplant and severity of the infection.
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39.
  • Fremat, Y., et al. (författare)
  • A test field for Gaia Radial velocity catalogue of stars in the South Ecliptic Pole
  • 2017
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 597
  • Tidskriftsartikel (refereegranskat)abstract
    • Context. Gaia is a space mission that is currently measuring the five astrometric parameters, as well as spectrophotometry of at least 1 billion stars to G = 20.7 mag with unprecedented precision. The sixth parameter in phase space (i.e., radial velocity) is also measured thanks to medium-resolution spectroscopy that is being obtained for the 150 million brightest stars. During the commissioning phase, two fields, one around each ecliptic pole, have been repeatedly observed to assess and to improve the overall satellite performances, as well as the associated reduction and analysis software. A ground-based photometric and spectroscopic survey was therefore initiated in 2007, and is still running to gather as much information as possible about the stars in these fields. This work is of particular interest to the validation of the radial velocity spectrometer outputs.Aims. The paper presents the radial velocity measurements performed for the Southern targets in the 12-17 R magnitude range on high-to mid-resolution spectra obtained with the GIRAFFE and UVES spectrographs.Methods. Comparison of the South Ecliptic Pole (SEP) GIRAFFE data to spectroscopic templates observed with the HERMES (Mercator in La Palma, Spain) spectrograph enabled a first coarse characterisation of the 747 SEP targets. Radial velocities were then obtained by comparing the results of three different methods.Results. In this paper, we present an initial overview of the targets to be found in the 1 sq. deg SEP region that was observed repeatedly by Gaia ever since its commissioning. In our representative sample, we identified one galaxy, six LMC S-stars, nine candidate chromospherically active stars, and confirmed the status of 18 LMC Carbon stars. A careful study of the 3471 epoch radial velocity measurements led us to identify 145 RV constant stars with radial velocities varying by less than 1 km s(-1). Seventy-eight stars show significant RV scatter, while nine stars show a composite spectrum. As expected, the distribution of the RVs exhibits two main peaks that correspond to Galactic and LMC stars. By combining [Fe/H] and log g estimates, and RV determinations, we identified 203 members of the LMC, while 51 more stars are candidate members.Conclusions. This is the first systematic spectroscopic characterisation of faint stars located in the SEP field. During the coming years, we plan to continue our survey and gather additional high-and mid-resolution data to better constrain our knowledge on key reference targets for Gaia.
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40.
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41.
  • Grachova, E V, et al. (författare)
  • The structure and dynamic behaviour of disubstituted derivatives of Rh6(CO)16 containing heterobidentate bridging phosphine ligands
  • 2003
  • Ingår i: Dalton Transactions. - : Royal Society of Chemistry (RSC). - 1477-9234 .- 1477-9226. ; :12, s. 2468-2473
  • Tidskriftsartikel (refereegranskat)abstract
    • The solution structures and dynamic behaviour of [Rh6(CO)14(µ-PX)][PX = diphenyl(2-pyridyl)phosphine, (PN); diphenyl(2-thienyl)phosphine, (PS); diphenyl(vinyl)phosphine, (PV)] have been studied by multinuclear NMR and the X-ray structure of [Rh6(CO)14(µ,3-PV)] is reported. In solution, the above clusters undergo a variety of localised CO-exchanges and the mechanisms of these are discussed. The PV ligand in [Rh6(CO)14(µ,3-PV)] is hemilabile and exhibits facile exchange/reorientation of the vinyl group.
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42.
  • Kabir, S E, et al. (författare)
  • Triiron and triruthenium carbonyl clusters bearing bridging long chain diphosphine and capping chalcogenido ligands
  • 2005
  • Ingår i: Journal of Cluster Science. - : Springer Science and Business Media LLC. - 1040-7278 .- 1572-8862. ; 16:1, s. 93-110
  • Tidskriftsartikel (refereegranskat)abstract
    • Treatment of Ru-3(CO)(12) with dpphSe(2) (dpph = 1,6-bis(diphenylphosphino)-hexane) in refluxing toluene in the presence of Me3NO afforded two new compounds, Ru-3(CO)(7)(mu-CO)(mu(3)-Se)(mu-dpph) (1) and Ru-3(CO)(7)(mu(3)-Se)(2)(mu-dpph) (2). A similar reaction of Ru-3(CO)(12) with dpppeSe(2)(dpppe=1,5-bis(diphenylphosphino)pentane) gave exclusively Ru-3(CO)(7)(mu(3)-Se)(2)(mu-dpppe) (3). Treatment of Ru-3(CO)(12) with dpphS(2) and dpppeS(2) at 110 degrees C in the presence of Me3NO afforded Ru-3(CO)(7)(mu(3)-S)(2)(mu-dpph) (4) and Ru-3(CO)(7)(mu(3)-S)(2)(mu-dpppe) (5), respectively. Reactions of Fe-3(CO)(12) with dpphSe(2) and dpppeSe(2), under identical conditions, afforded Fe-3(CO)(7)(mu(3)-Se)(2)(mu-dpph) (6) and Fe-3(CO)(7)(mu(3)-Se)(2)(mu-dpppe) (7), respectively. Compounds 1-7 were characterized spectroscopically and the molecular structures of compounds 1-4 were determined by single crystal X-ray crystallography. The core of 1 contains an equilateral triangle of ruthenium atoms with one capping selenium, one bridging dpph, one doubly bridging carbonyl and seven terminal carbonyl ligands. Complexes 2-4 have a square-pyramidal structure with two metal and two chalcogenide atoms alternating in the basal plane and the third metal atom at the apex of the pyramid, and belong to the family of well-known nido clusters with seven skeletal electron pairs.
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43.
  • Magrini, L., et al. (författare)
  • The Gaia-ESO survey : Mapping the shape and evolution of the radial abundance gradients with open clusters
  • 2023
  • Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 669
  • Tidskriftsartikel (refereegranskat)abstract
    • Context: The spatial distribution of elemental abundances and their time evolution are among the major constraints to disentangling the scenarios of formation and evolution of the Galaxy.Aims: In this paper we used the sample of open clusters available in the final release of the Gaia-ESO survey to trace the Galactic radial abundance and abundance-to-iron ratio gradients, and their time evolution.Methods: We selected member stars in 62 open clusters, with ages from 0.1 to about 7 Gyr, located in the Galactic thin disc at galactocentric radii (R-GC) from about 6 to 21 kpc. We analysed the shape of the resulting [Fe/H] gradient, the average gradients [El/H] and [El/Fe] combining elements belonging to four different nucleosynthesis channels, and their individual abundance and abundance ratio gradients. We also investigated the time evolution of the gradients dividing open clusters in three age bins.Results: The [Fe/H] gradient has a slope of -0.054 dex kpc(-1). It can be better approximated with a two-slope shape, steeper for R-GC <= 11.2 kpc and flatter in the outer regions. We saw different behaviours for elements belonging to different channels. For the time evolution of the gradient, we found that the youngest clusters (age < 1 Gyr) in the inner disc have lower metallicity than their older counterparts and that they outline a flatter gradient. We considered some possible explanations, including the effects of gas inflow and migration. We suggest that the most likely one may be related to a bias introduced by the standard spectroscopic analysis producing lower metallicities in the analysis of low-gravity stars.Conclusions: To delineate the shape of the 'true' gradient, we should most likely limit our analysis to stars with low surface gravity log g> 2.5 and microturbulent parameter xi< 1.8 km s(-1). Based on this reduced sample, we can conclude that the gradient has minimally evolved over the time-frame outlined by the open clusters, indicating a slow and stationary formation of the thin disc over the last 3 Gyr. We found a secondary role of cluster migration in shaping the gradient, with a more prominent role of migration for the oldest clusters.
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44.
  • Mckenzie, M., et al. (författare)
  • The complex stellar system M 22 : constraining the chemical enrichment from AGB stars using magnesium isotope ratios
  • 2023
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press. - 0035-8711 .- 1365-2966. ; 527:3, s. 7940-7955
  • Tidskriftsartikel (refereegranskat)abstract
    • The complex star cluster M 22 (NGC 6656) provides a unique opportunity for studying the slow neutron capture (s-)process nucleosynthesis at low metallicity due to its two stellar groups with distinct iron-peak and neutron capture element abundances. Previous studies attribute these abundance differences to pollution from 3 − 6 M asymptotic giant branch (AGB) stars which produce significant quantities of the neutron-rich Mg isotopes 25Mg and 26Mg. We report the first-ever measurements of Mg isotopic abundance ratios at [Fe/H] ∼ −2 in a globular cluster-like system using very high-resolution and signal-to-noise spectra (R = 110 000, S/N = 300 per pixel at 514 nm) from the VLT/UVES spectrograph for six stars; three in each s-process group. Despite the presence of star-to-star variations in 24Mg, 25Mg, and 26Mg, we find no correlation with heavy element abundances, implying that the nucleosynthetic source of s-process enrichment must not influence Mg isotope ratios. Instead, a key result of this work is that we identify correlations between 26Mg/24Mg and some light elements. Using a custom suite of AGB nucleosynthesis yields tailored to the metallicity of M 22, we find that low mass (∼ 1−3 M) AGB stars are capable of reproducing the observed s-process abundances of M 22 and that the absence of any difference in Mg isotope ratios between the two s-process groups precludes AGBs with masses above ∼ 3 M. This places tighter constraints on possible formation scenarios and suggests an age difference of at least ∼ 280−480 Myr between the two populations which is independent of isochrone fitting.
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45.
  • Zerjal, M., et al. (författare)
  • The GALAH Survey : Lithium-strong KM dwarfs
  • 2019
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 484:4, s. 4591-4600
  • Forskningsöversikt (refereegranskat)abstract
    • Identifying and characterizing young stars in the Solar neighbourhood is essential to find and describe planets in the early stages of their evolution. This work seeks to identify nearby young stars showing a lithium 6708 Å absorption line in the GALAH survey. A robust, data-driven approach is used to search for corresponding templates in the pool of 434 215 measured dwarf spectra in the survey. It enables a model-free search for best-matching spectral templates for all stars, including M dwarfs with strong molecular absorption bands. 3147 stars have been found to have measurable lithium: 1408 G and 892 K0-K5 dwarfs (EW(Li) > 0.1 Å), 335 K5-K9 (>0.07 Å) and 512 M0-M4 dwarfs (>0.05 Å). Stars with such lithium features are used to investigate the possibility of searching for young stars above the main sequence based merely on their parallaxes and broad-band photometry. The selection of young stars above the main sequence is highly effective for M dwarfs, moderately effective for K dwarfs and ineffective for G dwarfs. Using a combination of the lithium information and the complete 6D kinematics from Gaia and GALAH, 305 new candidate moving group members have been found, 123 of which belong to the Scorpius-Centaurus association, 36 to the Pleiades and 25 to the Hyades clusters.
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46.
  • Zinman, Paige S., et al. (författare)
  • Aminoquinoline-based Re(I) tricarbonyl complexes : Insights into their antiproliferative activity and mechanisms of action
  • 2024
  • Ingår i: European Journal of Medicinal Chemistry. - 0223-5234. ; 266
  • Tidskriftsartikel (refereegranskat)abstract
    • In an effort to develop new potent anticancer agents, two Schiff base rhenium(I) tricarbonyl complexes, containing the ubiquitous aminoquinoline scaffold, were synthesized. Both aminoquinoline ligands and Re(I) complexes showed adequate stability over a 48-h incubation period. Furthermore, the cytotoxic activity of the precursor ligands and rhenium(I) complexes were evaluated against the hormone-dependent MCF-7 and hormone-independent triple negative MDA-MB-231 breast cancer cell lines. Inclusion of the [Re(CO)3Cl]+ entity significantly enhanced the cytotoxicity of the aminoquinoline Schiff base ligands against the tested cancer cell lines. Remarkably, the incorporation of the Schiff-base iminoquinolyl entity notably enhanced the cytotoxic activity of the Re(I) complexes, in comparison with the iminopyridyl entity. Notably, the quinolyl-substituted complex showed up to three-fold higher activity than cisplatin against breast cancer cell lines, underpinning the significance of the quinoline pharmacophore in rational drug design. In addition, the most active Re(I) complex showed better selectivity towards the breast cancer cells over non-tumorigenic FG-0 cells. Western blotting revealed that the complexes increased levels of γH2AX, a key DNA damage response protein. Moreover, apoptosis was confirmed in both cell lines due to the detection of cleaved PARP. The complexes show favourable binding affinities towards both calf thymus DNA (CT-DNA), and bovine serum albumin (BSA), and the order of their interactions align with their cytotoxic effects. The in silico molecular simulations of the complexes were also performed with CT-DNA and BSA targets.
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47.
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48.
  • Azeem, Muhammad, et al. (författare)
  • Chemical composition and antifeedant activity of some aromatic plants against pine weevil (Hylobius abietis)
  • 2020
  • Ingår i: Annals of Applied Biology. - : Blackwell Publishing Ltd. - 0003-4746 .- 1744-7348.
  • Tidskriftsartikel (refereegranskat)abstract
    • The pine weevil Hylobius abietis is an important pest causing severe damage to conifer seedlings in reforestation areas in Europe and Asia. Plants that have no evolutionary history with the pine weevil are of special interest in the search for compounds with a strong antifeedant activity. Thus, the essential oils of nine aromatic plants, viz Amomum subulatum, Cinnamomum tamala, Curcuma longa, Laurus nobilis, Ocimum basilicum, Origanum majorana, Origanum vulgare, Syzygium aromaticum and Trachyspermum ammi were extracted by hydrodistillation. The essential oil constituents were identified by gas chromatography–mass spectrometry, and antifeedant properties towards the pine weevil were assessed using choice feeding bioassay. The essential oils of C. longa, O. majorana, S. aromaticum and T. ammi showed an excellent antifeedant activity towards the pine weevil for 24 hr, whereas the essential oil of other plants showed the activity for 6 hr. There was a positive correlation between the amount of benzenoid compounds and the antifeedant activity of the essential oils. This study suggests that pine weevil non-host plant compounds have potential to be used for the protection of seedlings against pine weevil feeding. However, further study will be needed to explore the antifeedant activity of individual components and oils in the laboratory as well as in the field. 
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49.
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50.
  • Barenius, B, et al. (författare)
  • Quality of life and clinical outcome after anterior cruciate ligament reconstruction using patellar tendon graft or quadrupled semitendinosus graft: an 8-year follow-up of a randomized controlled trial
  • 2010
  • Ingår i: The American journal of sports medicine. - : SAGE Publications. - 1552-3365 .- 0363-5465. ; 38:8, s. 1533-1541
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Randomized controlled trials after anterior cruciate ligament reconstructions with long-term follow-up including assessment of health-related quality of life are rare.Purpose: To compare clinical outcome and health-related quality of life 8 years after anterior cruciate ligament reconstruction using 2 types of graft.Study Design: Randomized controlled trial; Level of evidence, 1.Methods: Long-term follow-up of 164 patients with anterior cruciate ligament injury randomized to arthroscopic reconstruction with a quadrupled semitendinosus graft or a bone–patellar tendon–bone graft was undertaken. After a mean 8 years, 153 patients were available for follow-up, including instrumented laxity, 1-legged hop test, a knee-walking test, and assessment with International Knee Documentation Committee, Lysholm, Tegner, and patellofemoral pain score. Health-related quality of life was assessed with Knee Osteoarthritis Outcome Score and Short Form–36.Results: Patients in both graft groups retained the same stability, knee function, and health-related quality of life. The patellofemoral pain score was similar for both groups; the bone–patellar tendon–bone group had more donor site morbidity from kneeling and knee walking. In the bone–patellar tendon–bone group, 19 patients had no kneeling problems, 23 slight problems, 31 moderate problems, and 5 unable to kneel. Corresponding figures for the semitendinosus group were 25, 32, 16, and 2 ( P < .001). Patients with early reconstructions (<5 months) had a lower risk for meniscal injuries (37%) than did later reconstructed (62%, P = .008). Health-related quality of life regarding physical functioning in Short Form–36 was better for the early-reconstructed patients than for the later reconstructed (92 vs 85; P = .014). Patients without medial meniscal surgery had higher Knee Osteoarthritis Outcome Scores for all subscales than did patients with medial meniscal surgery, with most significant difference for sport and recreation (63 vs 75, P = .008).Conclusion: In the long term, the semitendinosus graft provided similar stability, knee function, and health-related quality of life but with less kneeling morbidity than did the bone–patellar tendon–bone graft.
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