| 1. |
- Bosson, J. K., et al.
(författare)
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Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations
- 2021
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Ingår i: Journal of Cross-Cultural Psychology. - : SAGE Publications. - 0022-0221 .- 1552-5422. ; 52:3
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Tidskriftsartikel (refereegranskat)abstract
- Precarious manhood beliefs portray manhood, relative to womanhood, as a social status that is hard to earn, easy to lose, and proven via public action. Here, we present cross-cultural data on a brief measure of precarious manhood beliefs (the Precarious Manhood Beliefs scale [PMB]) that covaries meaningfully with other cross-culturally validated gender ideologies and with country-level indices of gender equality and human development. Using data from university samples in 62 countries across 13 world regions (N = 33,417), we demonstrate: (1) the psychometric isomorphism of the PMB (i.e., its comparability in meaning and statistical properties across the individual and country levels); (2) the PMB's distinctness from, and associations with, ambivalent sexism and ambivalence toward men; and (3) associations of the PMB with nation-level gender equality and human development. Findings are discussed in terms of their statistical and theoretical implications for understanding widely-held beliefs about the precariousness of the male gender role.
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| 2. |
- Cvitic, Petya Hristova, et al.
(författare)
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Investigating Software Testing and Maintenance of Open-Source Distributed Ledger
- 2023
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Ingår i: Proceedings - 2023 IEEE International Conference on Software Analysis, Evolution and Reengineering, SANER 2023. - : IEEE conference proceedings. - 9781665452786 ; , s. 886-896
-
Konferensbidrag (refereegranskat)abstract
- A distributed ledger is the backbone of all blockchain solutions. It provides a shared database spreading across a network of nodes. The number of DL solutions and their implementations has grown in recent years. Besides the architectural and performance promises of these solutions, organizations seekingto implement DL also need to consider the overall quality of the software available and its ecosystem. Particularly, previous research has identified the need to better understand the testing and maintenance practices behind these types of technologies. This paper investigates the testing and maintenance of 18 different open-source projects that implement distributed ledgers. We perform a manual inspection of test artefacts and mine the history of commits, issues and contributors of the chosen projects to understand the landscape of testing and maintenance in these projects. Our findings suggest that unit and integration tests are present in most projects, they do not follow a holistic system testing approach. Moreover, projects rely on a small team of core contributors (5 on average). While the projects are continuously maintained, larger changes are uncommon. Our results can be used for benchmarking and pinpointing areas of improvement for the development of distributed ledgers.
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| 3. |
- Cvitic, Petya Hristova, et al.
(författare)
-
Investigating Software Testing and Maintenance of Open-Source Distributed Ledger
- 2023
-
Ingår i: Proceedings - 2023 IEEE International Conference on Software Analysis, Evolution and Reengineering, SANER 2023. - : IEEE. - 2833-9061. - 9781665452786
-
Konferensbidrag (refereegranskat)abstract
- A distributed ledger is the backbone of all blockchain solutions. It provides a shared database spreading across a network of nodes. The number of DL solutions and their implementations has grown in recent years. Besides the architectural and performance promises of thesesolutions, organizations seekingto implement DL also need to consider the overall quality of the software available and its ecosystem. Particularly, previous research has identified the need to better understand the testing and maintenance practices behind these types of technologies. This paper investigates the testing and maintenance of 18 different open-source projects that implement distributed ledgers. We perform a manual inspection of test artefacts and mine the history of commits, issues and contributors of the chosen projects to understand the landscape of testing and maintenance in these projects. Our findings suggest that unit and integration tests are present in most projects, they do not follow a holistic system testing approach. Moreover, projects rely on a small team of core contributors (5 on average). While the projects are continuously maintained, larger changes are uncommon. Our results can be used for benchmarking and pinpointing areas of improvement for the development of distributed ledgers.
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| 4. |
- de Oliveira Neto, Francisco Gomes, et al.
(författare)
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Building Collaborative Learning : Exploring Social Annotation in Introductory Programming
- 2024
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Ingår i: Proceedings - International Conference on Software Engineering. - : IEEE Computer Society. - 9798400704987 ; , s. 12-21
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Konferensbidrag (refereegranskat)abstract
- The increasing demand for software engineering education presents learning challenges in courses due to the diverse range of topics that require practical applications, such as programming or software design, all of which are supported by group work and interaction. Social Annotation (SA) is an approach to teaching that can enhance collaborative learning among students. In SA, both students and teachers utilize platforms like Feedback Fruits, Perusall, and Diigo to collaboratively annotate and discuss course materials. This approach encourages students to share their thoughts and answers with their peers, fostering a more interactive learning environment. We share our experience of implementing social annotation via Perusall as a preparatory tool for lectures in an introductory programming course aimed at undergraduate students in Software Engineering. We report the impact of Perusall on the examination results of 112 students. Our results show that 81% of students engaged in meaningful social annotation successfully passed the course. Notably, the proportion of students passing the exam tends to rise as they complete more Perusall assignments. In contrast, only 56% of students who did not participate in Perusall discussions managed to pass the exam. We did not enforce mandatory Perusall participation in the course. Yet, the feedback from our course evaluation questionnaire reveals that most students ranked Perusall among their favorite components of the course and that their interest in the subject has increased.
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| 5. |
- Dobslaw, Felix, 1983-, et al.
(författare)
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Automated black-box boundary value detection
- 2023
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Ingår i: PeerJ Computer Science. - : PeerJ. - 2376-5992. ; 9
-
Tidskriftsartikel (refereegranskat)abstract
- Abstract Software systems typically have an input domain that can be subdivided into sub-domains, each of which generates similar or related outputs. Testing it on the boundaries between these sub-domains is critical to ensure high-quality software. Therefore, boundary value analysis and testing have been a fundamental part of the software testing toolbox for a long time and are typically taught early to software engineering students. Despite its many argued benefits, boundary value analysis for a given software specification or application is typically described in abstract terms. This allows for variation in how testers apply it and in the benefits they see. Additionally, its adoption has been limited since it requires a specification or model to be analysed. We propose an automated black-box boundary value detection method to support software testers in performing systematic boundary value analysis. This dynamic method can be utilized even without a specification or model. The proposed method is based on a metric referred to as the program derivative, which quantifies the level of boundariness of test inputs. By combining this metric with search algorithms, we can identify and rank pairs of inputs as good boundary candidates, i.e., inputs that are in close proximity to each other but with outputs that are far apart. We have implemented the AutoBVA approach and evaluated it on a curated dataset of example programs. Furthermore, we have applied the approach broadly to a sample of 613 functions from the base library of the Julia programming language. The approach could identify boundary candidates that highlight diverse boundary behaviours in over 70% of investigated systems under test. The results demonstrate that even a simple variant of the program derivative, combined with broad sampling and search over the input space, can identify interesting boundary candidates for a significant portion of the functions under investigation. In conclusion, we also discuss the future extension of the approach to encompass more complex systems under test cases and datatypes.
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| 6. |
- Dobslaw, Felix, et al.
(författare)
-
Automated black-box boundary value detection
- 2023
-
Ingår i: PeerJ Computer Science. - 2376-5992. ; 9
-
Tidskriftsartikel (refereegranskat)abstract
- Software systems typically have an input domain that can be subdivided into subdomains, each of which generates similar or related outputs. Testing it on the boundaries between these sub-domains is critical to ensure high-quality software. Therefore, boundary value analysis and testing have been a fundamental part of the software testing toolbox for a long time and are typically taught early to software engineering students. Despite its many argued benefits, boundary value analysis for a given software specification or application is typically described in abstract terms. This allows for variation in how testers apply it and in the benefits they see. Additionally, its adoption has been limited since it requires a specification or model to be analysed. We propose an automated black-box boundary value detection method to support software testers in performing systematic boundary value analysis. This dynamic method can be utilized even without a specification or model. The proposed method is based on a metric referred to as the program derivative, which quantifies the level of boundariness of test inputs. By combining this metric with search algorithms, we can identify and rank pairs of inputs as good boundary candidates, i.e., inputs that are in close proximity to each other but with outputs that are far apart. We have implemented the AutoBVA approach and evaluated it on a curated dataset of example programs. Furthermore, we have applied the approach broadly to a sample of 613 functions from the base library of the Julia programming language. The approach could identify boundary candidates that highlight diverse boundary behaviours in over 70% of investigated systems under test. The results demonstrate that even a simple variant of the program derivative, combined with broad sampling and search over the input space, can identify interesting boundary candidates for a significant portion of the functions under investigation. In conclusion, we also discuss the future extension of the approach to encompass more complex systems under test cases and datatypes.
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| 7. |
- Dobslaw, Felix, et al.
(författare)
-
Automated black-box boundary value detection
- 2023
-
Ingår i: PeerJ Computer Science. - 2376-5992. ; 9
-
Tidskriftsartikel (refereegranskat)abstract
- Software systems typically have an input domain that can be subdivided into subdomains, each of which generates similar or related outputs. Testing it on the boundaries between these sub-domains is critical to ensure high-quality software. Therefore, boundary value analysis and testing have been a fundamental part of the software testing toolbox for a long time and are typically taught early to software engineering students. Despite its many argued benefits, boundary value analysis for a given software specification or application is typically described in abstract terms. This allows for variation in how testers apply it and in the benefits they see. Additionally, its adoption has been limited since it requires a specification or model to be analysed. We propose an automated black-box boundary value detection method to support software testers in performing systematic boundary value analysis. This dynamic method can be utilized even without a specification or model. The proposed method is based on a metric referred to as the program derivative, which quantifies the level of boundariness of test inputs. By combining this metric with search algorithms, we can identify and rank pairs of inputs as good boundary candidates, i.e., inputs that are in close proximity to each other but with outputs that are far apart. We have implemented the AutoBVA approach and evaluated it on a curated dataset of example programs. Furthermore, we have applied the approach broadly to a sample of 613 functions from the base library of the Julia programming language. The approach could identify boundary candidates that highlight diverse boundary behaviours in over 70% of investigated systems under test. The results demonstrate that even a simple variant of the program derivative, combined with broad sampling and search over the input space, can identify interesting boundary candidates for a significant portion of the functions under investigation. In conclusion, we also discuss the future extension of the approach to encompass more complex systems under test cases and datatypes.
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| 8. |
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| 9. |
- Felix Garrido, Ananda Lais, et al.
(författare)
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Eating habits, sleep, and a proxy for circadian disruption are correlated with dyslipidemia in overweight night workers
- 2021
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Ingår i: Nutrition (Burbank, Los Angeles County, Calif.). - : Elsevier BV. - 0899-9007 .- 1873-1244. ; 83
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this study was to evaluate the relationship between proxy for circadian disruption, eating habits, sleep characteristics, and dyslipidemic parameters.Methods: This was a randomized, double-blind, crossover controlled clinical trial, and for this study, only baseline data were used. The sample was composed of 36 overweight female nurses who worked on a fixed night shift (12 × 36 h). Linear regression models were used to assess the relationship between the mentioned variables.Results: The participants’ average age was 39.4 y (Standard error (SE) 1 y) and the average nighttime sleep duration was 5.76 h (SE 0.16 h). The average chronotype indicated a moderate early type (03:03 h; SE 20 min) and the average social jetlag was 03:42 h (SE 10 min). It was found that 1 h less of nighttime sleep increased very-low-density lipoprotein cholesterol levels by 2.75 mg/dL and triacylglyceride levels by 3.62 mg/dL. Additionally, higher social jetlag was associated with higher low-density lipoprotein cholesterol levels. On the other hand, each additional hour in the chronotype increased high-density lipoprotein cholesterol levels by 3.06 mg/dL and a time interval >2 h between the last meal and sleep onset was associated with higher high-density lipoprotein cholesterol levels.Conclusion: Short duration of nighttime sleep and high social jetlag are risk factors for dyslipidemia, whereas the late type and the longer time interval between the last meal and sleep onset appear to be protective factors for dyslipidemia.
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| 10. |
- He, Jia, et al.
(författare)
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Socially Desirable Responding : Enhancement and Denial in 20 Countries
- 2015
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Ingår i: Cross-cultural research. - : SAGE Publications. - 1069-3971 .- 1552-3578. ; 49:3, s. 227-249
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Tidskriftsartikel (refereegranskat)abstract
- This article investigated the dimensionality, measurement invariance, and cross-cultural variations of social desirability. A total of 3,471 university students from 20 countries completed an adapted version of the Marlowe-Crowne scale. A two-dimensional structure was revealed in the pooled sample, distinguishing enhancement (endorsement of positive self-description) and denial (rejection of negative self-description). The factor structure was supported in most countries; medium-sized item bias was found in two denial items. In a multilevel analysis, we found that (a) there was more cross-cultural variation in denial than enhancement; (b) females tended to score higher on enhancement whereas males tended to score higher on denial; (c) the Human Development Index, an indicator of country socioeconomic development, was the best (negative) predictor of denial; and (d) both enhancement and denial seemed to be associated with country-level values and personality pertinent to fitting in. We conclude that social desirability has a positive and a negative impression management dimension that are meaningfully associated with country-level characteristics, and we argue that social desirability is better interpreted as culturally regulated response amplification.
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| 11. |
- Hyde, K. D., et al.
(författare)
-
Global consortium for the classification of fungi and fungus-like taxa
- 2023
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Ingår i: MYCOSPHERE. - : Mushroom Research Foundation. - 2077-7000 .- 2077-7019. ; 14:1, s. 1960-2012
-
Tidskriftsartikel (refereegranskat)abstract
- The Global Consortium for the Classification of Fungi and fungus-like taxa is an international initiative of more than 550 mycologists to develop an electronic structure for the classification of these organisms. The members of the Consortium originate from 55 countries/regions worldwide, from a wide range of disciplines, and include senior, mid-career and early-career mycologists and plant pathologists. The Consortium will publish a biannual update of the Outline of Fungi and fungus-like taxa, to act as an international scheme for other scientists. Notes on all newly published taxa at or above the level of species will be prepared and published online on the Outline of Fungi website (https://www.outlineoffungi.org/), and these will be finally published in the biannual edition of the Outline of Fungi and fungus-like taxa. Comments on recent important taxonomic opinions on controversial topics will be included in the biannual outline. For example, 'to promote a more stable taxonomy in Fusarium given the divergences over its generic delimitation', or 'are there too many genera in the Boletales?' and even more importantly, 'what should be done with the tremendously diverse 'dark fungal taxa?' There are undeniable differences in mycologists' perceptions and opinions regarding species classification as well as the establishment of new species. Given the pluralistic nature of fungal taxonomy and its implications for species concepts and the nature of species, this consortium aims to provide a platform to better refine and stabilise fungal classification, taking into consideration views from different parties. In the future, a confidential voting system will be set up to gauge the opinions of all mycologists in the Consortium on important topics. The results of such surveys will be presented to the International Commission on the Taxonomy of Fungi (ICTF) and the Nomenclature Committee for Fungi (NCF) with opinions and percentages of votes for and against. Criticisms based on scientific evidence with regards to nomenclature, classifications, and taxonomic concepts will be welcomed, and any recommendations on specific taxonomic issues will also be encouraged; however, we will encourage professionally and ethically responsible criticisms of others' work. This biannual ongoing project will provide an outlet for advances in various topics of fungal classification, nomenclature, and taxonomic concepts and lead to a community-agreed classification scheme for the fungi and fungus-like taxa. Interested parties should contact the lead author if they would like to be involved in future outlines.
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| 12. |
- Jovanović, Veljko, et al.
(författare)
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The Satisfaction with Life Scale in Adolescent Samples : Measurement Invariance across 24 Countries and Regions, Age, and Gender
- 2022
-
Ingår i: Applied Research in Quality of Life. - : Springer Science and Business Media LLC. - 1871-2584 .- 1871-2576. ; 17:4, s. 2139-2161
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Tidskriftsartikel (refereegranskat)abstract
- Measurement of adolescent life satisfaction across cultures has not received much attention in previous empirical research. The present study evaluated measurement invariance of the Satisfaction with Life Scale (SWLS) among adolescents in 24 countries and regions (N = 22,710; age range = 13–19 years; 53% female). A single-factor model with residual covariance between a pair of items tapping past life satisfaction fitted well in 19 countries and regions and showed a partial metric invariance. In a subset of nine countries and regions, partial scalar invariance was supported. Partial metric invariance across all 24 countries and regions was achieved when custom model modifications in five countries and regions were included. Three SWLS items showed evidence of noninvariance across cultures. The measurement model was found to operate similarly across gender and age. Our findings suggest that caution is needed when using the SWLS for measuring life satisfaction among adolescents from different cultures.
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| 13. |
- Marini, Maddalena, et al.
(författare)
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Overweight People Have Low Levels of Implicit Weight Bias, but Overweight Nations Have High Levels of Implicit Weight Bias
- 2013
-
Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 8:12
-
Tidskriftsartikel (refereegranskat)abstract
- Although a greater degree of personal obesity is associated with weaker negativity toward overweight people on both explicit (i.e., self-report) and implicit (i.e., indirect behavioral) measures, overweight people still prefer thin people on average. We investigated whether the national and cultural context - particularly the national prevalence of obesity predicts attitudes toward overweight people independent of personal identity and weight status. Data were collected from a total sample of 338,121 citizens from 71 nations in 22 different languages on the Project Implicit website (https://implicit.harvard.edu/) between May 2006 and October 2010. We investigated the relationship of the explicit and implicit weight bias with the obesity both at the individual (i.e., across individuals) and national (i.e., across nations) level. Explicit weight bias was assessed with self-reported preference between overweight and thin people; implicit weight bias was measured with the Implicit Association Test (IAT). The national estimates of explicit and implicit weight bias were obtained by averaging the individual scores for each nation. Obesity at the individual level was defined as Body Mass Index (BMI) scores, whereas obesity at the national level was defined as three national weight indicators (national BMI, national percentage of overweight and underweight people) obtained from publicly available databases. Across individuals, greater degree of obesity was associated with weaker implicit negativity toward overweight people compared to thin people. Across nations, in contrast, a greater degree of national obesity was associated with stronger implicit negativity toward overweight people compared to thin people. This result indicates a different relationship between obesity and implicit weight bias at the individual and national levels.
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| 14. |
- Neto, Fèlix, et al.
(författare)
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Measurement Invariance of the Satisfaction with Love Life Scale Among Emerging Adults in Angola, Brazil, East Timor, Macao, and Portugal
- 2017
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Ingår i: Well-Being of Youth and Emerging Adults across Cultures. - Cham : Springer. - 9783319683621 - 9783319683638 ; , s. 249-260
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The current chapter evaluates the measurement invariance of a recently developed instrument, the Satisfaction with Love Life Scale (SWLLS, Neto. Meas Eval Couns Dev 38:2-13, 2005) in a cross-sectional study sampling 1113 emerging adults from Angola, Brazil, East Timor, Macao, and Portugal. A multigroup confirmatory factor analysis showed a good fit of a configural, measurement weights and partial scalar invariance model, indicating similar patterns and strengths in factor loadings, means and intercepts across samples. We conclude that the SWLLS shows brief and valid test scores of love life satisfaction that is suitable for use in cross-cultural survey with emerging adults.
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| 15. |
- Nosek, Brian A., et al.
(författare)
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National differences in gender-science stereotypes predict national sex differences in science and math achievement
- 2009
-
Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 106:26, s. 10593-10597
-
Tidskriftsartikel (refereegranskat)abstract
- About 70% of more than half a million Implicit Association Tests completed by citizens of 34 countries revealed expected implicit stereotypes associating science with males more than with females. We discovered that nation-level implicit stereotypes predicted nation-level sex differences in 8th-grade science and mathematics achievement. Self-reported stereotypes did not provide additional predictive validity of the achievement gap. We suggest that implicit stereotypes and sex differences in science participation and performance are mutually reinforcing, contributing to the persistent gender gap in science engagement.
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| 16. |
- Oliveira, Aldair J., et al.
(författare)
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Psychosocial and environmental determinants of physical activity in a Brazilian public university employees - ELDAF : A prospective cohort study protocol
- 2022
-
Ingår i: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 17:2
-
Tidskriftsartikel (refereegranskat)abstract
- BackgroundIncreased physical activity levels and their determinations are essential issues worldwide. The Longitudinal Study of Physical Activity Determinants (ELDAF) aims to understand the roles of psychosocial and environmental factors in workers’ physical activity levels.MethodsA prospective cohort study of non-faculty civil servants from a public university (approximately 1,200 individuals) will start in 2022 (baseline). The primary measurements will be accelerometer- and questionnaire-based physical activity, social support, social network, socioeconomic status, bereavement, job stress, body image, common mental disorders, depression, and neighborhood satisfaction. Additional measurements will include necessary sociodemographic, physical morbidity, lifestyle and anthropometric information. Participants’ places of residence will be geocoded using complete addresses. All participants will furnish written, informed consent before the beginning of the study. Pilot studies were performed to identify and correct potential problems in the data collection instruments and procedures. ELDAF will be the first cohort study conducted in Latin America to investigate physical activity and its determinants.
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| 17. |
- Sam, David L., et al.
(författare)
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Immigration, acculturation and the paradox of adaptation in Europe
- 2008
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Ingår i: European Journal of Developmental Psychology. - : Informa UK Limited. - 1740-5629 .- 1740-5610. ; 5:2, s. 138-158
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Tidskriftsartikel (refereegranskat)abstract
- Drawing from the International Comparative Study of Ethnocultural Youth (ICSEY) dataset, this paper examines the immigrant paradox phenomenon among a group of immigrant youth in five European countries. The sample consisted of over 2700 immigrant and 1400 national youth (age range 13-18 years) living in Finland, the Netherlands, Norway, Portugal and Sweden. At the core of the immigrant paradox is the counterintuitive finding that immigrants often show better adaptation outcomes than their national peers in spite of poorer socioeconomic status. However, the paper argues for a more conservative position based on three criteria for concluding the existence of the paradox. On the bases of these criteria, the paper found mixed support for the immigrant paradox. Whereas the pattern of socio-cultural adaptation for first- and second-generation immigrants resembled the immigrant paradox, results for psychological adaptation were opposite to the paradox. Reasons for the mixed findings are discussed.
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| 18. |
- Sanchez-Rodriguez, Lazaro M, et al.
(författare)
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Personalized whole-brain neural mass models reveal combined Aβ and tau hyperexcitable influences in Alzheimer's disease.
- 2024
-
Ingår i: Communications biology. - 2399-3642. ; 7:1
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Tidskriftsartikel (refereegranskat)abstract
- Neuronal dysfunction and cognitive deterioration in Alzheimer's disease (AD) are likely caused by multiple pathophysiological factors. However, mechanistic evidence in humans remains scarce, requiring improved non-invasive techniques and integrative models. We introduce personalized AD computational models built on whole-brain Wilson-Cowan oscillators and incorporating resting-state functional MRI, amyloid-β (Aβ) and tau-PET from 132 individuals in the AD spectrum to evaluate the direct impact of toxic protein deposition on neuronal activity. This subject-specific approach uncovers key patho-mechanistic interactions, including synergistic Aβ and tau effects on cognitive impairment and neuronal excitability increases with disease progression. The data-derived neuronal excitability values strongly predict clinically relevant AD plasma biomarker concentrations (p-tau217, p-tau231, p-tau181, GFAP) and grey matter atrophy obtained through voxel-based morphometry. Furthermore, reconstructed EEG proxy quantities show the hallmark AD electrophysiological alterations (theta band activity enhancement and alpha reductions) which occur with Aβ-positivity and after limbic tau involvement. Microglial activation influences on neuronal activity are less definitive, potentially due to neuroimaging limitations in mapping neuroprotective vs detrimental activation phenotypes. Mechanistic brain activity models can further clarify intricate neurodegenerative processes and accelerate preventive/treatment interventions.
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| 19. |
- Sanchez-Rodriguez, Lazaro M, et al.
(författare)
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Revealing the combined roles of Aβ and tau in Alzheimer's disease via a pathophysiological activity decoder.
- 2023
-
Ingår i: bioRxiv : the preprint server for biology. - : Cold Spring Harbor Laboratory.
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Neuronal dysfunction and cognitive deterioration in Alzheimer's disease (AD) are likely caused by multiple pathophysiological factors. However, evidence in humans remains scarce, necessitating improved non-invasive techniques and integrative mechanistic models. Here, we introduce personalized brain activity models incorporating functional MRI, amyloid-β (Aβ) and tau-PET from AD-related participants (N=132). Within the model assumptions, electrophysiological activity is mediated by toxic protein deposition. Our integrative subject-specific approach uncovers key patho-mechanistic interactions, including synergistic Aβ and tau effects on cognitive impairment and neuronal excitability increases with disease progression. The data-derived neuronal excitability values strongly predict clinically relevant AD plasma biomarker concentrations (p-tau217, p-tau231, p-tau181, GFAP). Furthermore, our results reproduce hallmark AD electrophysiological alterations (theta band activity enhancement and alpha reductions) which occur with Aβ-positivity and after limbic tau involvement. Microglial activation influences on neuronal activity are less definitive, potentially due to neuroimaging limitations in mapping neuroprotective vs detrimental phenotypes. Mechanistic brain activity models can further clarify intricate neurodegenerative processes and accelerate preventive/treatment interventions.
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| 20. |
- Swami, Viren, et al.
(författare)
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The Attractive Female Body Weight and Female Body Dissatisfaction in 26 Countries Across 10 World Regions : Results of the International Body Project I
- 2010
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Ingår i: Personality and Social Psychology Bulletin. - : Sage Publications. - 0146-1672 .- 1552-7433. ; 36:3, s. 309-325
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Tidskriftsartikel (refereegranskat)abstract
- This study reports results from the first International Body Project (IBP-I), which surveyed 7,434 individuals in 10 major world regions about body weight ideals and body dissatisfaction. Participants completed the female Contour Drawing Figure Rating Scale (CDFRS) and self-reported their exposure to Western and local media. Results indicated there were significant cross-regional differences in the ideal female figure and body dissatisfaction, but effect sizes were small across high-socioeconomic-status (SES) sites. Within cultures, heavier bodies were preferred in low-SES sites compared to high-SES sites in Malaysia and South Africa (ds = 1.94-2.49) but not in Austria. Participant age, body mass index (BMI), and Western media exposure predicted body weight ideals. BMI and Western media exposure predicted body dissatisfaction among women. Our results show that body dissatisfaction and desire for thinness is commonplace in high-SES settings across world regions, highlighting the need for international attention to this problem.
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| 21. |
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