| 1. |
- Vu, Tung T., et al.
(författare)
-
Energy-Efficient Massive MIMO for Serving Multiple Federated Learning Groups
- 2021
-
Ingår i: 2021 IEEE GLOBAL COMMUNICATIONS CONFERENCE (GLOBECOM). - : IEEE. - 9781728181042
-
Konferensbidrag (refereegranskat)abstract
- With its privacy preservation and communication efficiency, federated learning (FL) has emerged as a learning framework that suits beyond SG and towards 6G systems. This work looks into a future scenario in which there are multiple groups with different learning purposes and participating in different FL processes. We give energy-efficient solutions to demonstrate that this scenario can be realistic. First, to ensure a stable operation of multiple FL processes over wireless channels, we propose to use a massive multiple-input multiple-output network to support the local and global FL training updates, and let the iterations of these FL processes be executed within the same large-scale coherence time. Then, we develop asynchronous and synchronous transmission protocols where these iterations are asynchronously and synchronously executed, respectively, using the downlink unicasting and conventional uplink transmission schemes. Zero-forcing processing is utilized for both uplink and downlink transmissions. Finally, we propose an algorithm that optimally allocates power and computation resources to save energy at both base station and user sides, while guaranteeing a given maximum execution time threshold of each FL iteration. Compared to the baseline schemes, the proposed algorithm significantly reduces the energy consumption, especially when the number of base station antennas is large.
|
|
| 2. |
- Gunst, Jesper D., et al.
(författare)
-
Efficacy of the TMPRSS2 inhibitor camostat mesilate in patients hospitalized with Covid-19-a double-blind randomized controlled trial
- 2021
-
Ingår i: eClinicalMedicine. - : Elsevier. - 2589-5370. ; 35
-
Tidskriftsartikel (refereegranskat)abstract
- Background: The trans-membrane protease serine 2 (TMPRSS2) is essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry and infection. Efficacy and safety of TMPRSS2 inhibitors in patients with coronavirus disease 2019 (Covid-19) have not been evaluated in randomized trials.Methods: We conducted an investigator-initiated, double-blind, randomized, placebo-controlled multicenter trial in patients hospitalized with confirmed SARS-CoV-2 infection from April 4, to December 31, 2020. Within 48 h of admission, participants were randomly assigned in a 2:1 ratio to receive the TMPRSS2 inhibitor camostat mesilate 200 mg three times daily for 5 days or placebo. The primary outcome was time to discharge or clinical improvement measured as ≥2 points improvement on a 7-point ordinal scale. Other outcomes included 30-day mortality, safety and change in oropharyngeal viral load. ClinicalTrials.gov Identifier: NCT04321096. EudraCT Number: 2020-001,200-42.Findings: 137 patients were assigned to receive camostat mesilate and 68 to placebo. Median time to clinical improvement was 5 days (interquartile range [IQR], 3 to 7) in the camostat group and 5 days (IQR, 2 to 10) in the placebo group (P = 0·31). The hazard ratio for 30-day mortality in the camostat compared with the placebo group was 0·82 (95% confidence interval [CI], 0·24 to 2·79; P = 0·75). The frequency of adverse events was similar in the two groups. Median change in viral load from baseline to day 5 in the camostat group was -0·22 log10 copies/mL (p <0·05) and -0·82 log10 in the placebo group (P <0·05).Interpretation: Under this protocol, camostat mesilate treatment was not associated with increased adverse events during hospitalization for Covid-19 and did not affect time to clinical improvement, progression to ICU admission or mortality.
|
|
| 3. |
- Rosa, Isabel M. D., et al.
(författare)
-
Multiscale scenarios for nature futures
- 2017
-
Ingår i: Nature Ecology & Evolution. - : Springer Science and Business Media LLC. - 2397-334X. ; 1:10, s. 1416-1419
-
Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Targets for human development are increasingly connected with targets for nature, however, existing scenarios do not explicitly address this relationship. Here, we outline a strategy to generate scenarios centred on our relationship with nature to inform decision-making at multiple scales.
|
|
| 4. |
- Chan, Kai M. A., et al.
(författare)
-
Levers and leverage points for pathways to sustainability
- 2020
-
Ingår i: People and Nature. - : Wiley. - 2575-8314. ; 2:3, s. 693-717
-
Tidskriftsartikel (refereegranskat)abstract
- 1. Humanity is on a deeply unsustainable trajectory. We are exceeding planetary boundaries and unlikely to meet many international sustainable development goals and global environmental targets. Until recently, there was no broadly accepted framework of interventions that could ignite the transformations needed to achieve these desired targets and goals.2. As a component of the IPBES Global Assessment, we conducted an iterative expert deliberation process with an extensive review of scenarios and pathways to sustainability, including the broader literature on indirect drivers, social change and sustainability transformation. We asked, what are the most important elements of pathways to sustainability?3. Applying a social-ecological systems lens, we identified eight priority points for intervention (leverage points) and five overarching strategic actions and priority interventions (levers), which appear to be key to societal transformation. The eight leverage points are: (1) Visions of a good life, (2) Total consumption and waste, (3) Latent values of responsibility, (4) Inequalities, (5) Justice and inclusion in conservation, (6) Externalities from trade and other telecouplings, (7) Responsible technology, innovation and investment, and (8) Education and knowledge generation and sharing. The five intertwined levers can be applied across the eight leverage points and more broadly. These include: (A) Incentives and capacity building, (B) Coordination across sectors and jurisdictions, (C) Pre-emptive action, (D) Adaptive decision-making and (E) Environmental law and implementation. The levers and leverage points are all non-substitutable, and each enables others, likely leading to synergistic benefits.4. Transformative change towards sustainable pathways requires more than a simple scaling-up of sustainability initiatives-it entails addressing these levers and leverage points to change the fabric of legal, political, economic and other social systems. These levers and leverage points build upon those approved within the Global Assessment's Summary for Policymakers, with the aim of enabling leaders in government, business, civil society and academia to spark transformative changes towards a more just and sustainable world.
|
|
| 5. |
- Diaz, Sandra, et al.
(författare)
-
Pervasive human-driven decline of life on Earth points to the need for transformative change
- 2019
-
Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 366:6471
-
Forskningsöversikt (refereegranskat)abstract
- The human impact on life on Earth has increased sharply since the 1970s, driven by the demands of a growing population with rising average per capita income. Nature is currently supplying more materials than ever before, but this has come at the high cost of unprecedented global declines in the extent and integrity of ecosystems, distinctness of local ecological communities, abundance and number of wild species, and the number of local domesticated varieties. Such changes reduce vital benefits that people receive from nature and threaten the quality of life of future generations. Both the benefits of an expanding economy and the costs of reducing nature's benefits are unequally distributed. The fabric of life on which we all depend-nature and its contributions to people-is unravelling rapidly. Despite the severity of the threats and lack of enough progress in tackling them to date, opportunities exist to change future trajectories through transformative action. Such action must begin immediately, however, and address the root economic, social, and technological causes of nature's deterioration.
|
|
| 6. |
- Vu, Tung T., et al.
(författare)
-
Data Size-Aware Downlink Massive MIMO: A Session-Based Approach
- 2022
-
Ingår i: IEEE Wireless Communications Letters. - : IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC. - 2162-2337 .- 2162-2345. ; 11:7, s. 1468-1472
-
Tidskriftsartikel (refereegranskat)abstract
- This letter considers the development of transmission strategies for the downlink of massive multiple-input multiple-output networks, with the objective of minimizing the completion time of the transmission. Specifically, we introduce a session-based scheme that splits time into sessions and allocates different rates in different sessions for the different users. In each session, one user is selected to complete its transmission and will not join subsequent sessions, which results in successively lower levels of interference when moving from one session to the next. An algorithm is developed to assign users and allocate transmit power that minimizes the completion time. Numerical results show that our proposed session-based scheme significantly outperforms conventional non-session-based schemes.
|
|
