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| 2. |
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| 3. |
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| 4. |
- Bijelic, Tessa, et al.
(författare)
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Expectations and Experiences of Internet-Based Therapy for Adolescents with TMD Pain
- 2022
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Ingår i: JOURNAL OF ORAL & FACIAL PAIN AND HEADACHE. - : QUINTESSENCE PUBLISHING CO INC. - 2333-0384 .- 2333-0376. ; 36:3, s. 237-252
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Tidskriftsartikel (refereegranskat)abstract
- Aims: To investigate expectations and experiences of internet-based therapy (IBT) in adolescents with temporomandibular disorder (TMD) pain. Methods: Seven adolescents were strategically selected for this study. All patients had received IBT for their TMD pain in a previous randomized controlled trial. One-on-one interviews were conducted in a nonclinical setting. The interviews were semi-structured, following an interview guide with six domains. The recorded interviews were transcribed, and a qualitative inductive content analysis was then performed. Results: Content analysis indicated that the expectations of the adolescents and their experiences of IBT as a treatment for TMD pain can be understood in light of three main categories: (1) To become better; (2) An ambivalent experience; and (3) A personal challenge. The adolescents expressed expectations of less TMD pain after treatment, but also of improvement in general well-being and everyday life. Although their experiences of IBT varied, adolescents described having mixed feelings about treatment and feeling that it was personally challenging. Conclusion: Gained understanding of expectations and experiences is a necessary basis for revising the IBT program to meet the demands of adolescents and to improve treatment adherence. Furthermore, the content of the three categories clarifies the values of adolescents, and this understanding can in turn contribute to the development of new patient -centered treatment programs.
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| 5. |
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| 6. |
- Dell'Unto, Nicolo, et al.
(författare)
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Förhallen i Dalby som dopkapell : en digital rekonstruktion
- 2013
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Ingår i: ALE. - 0345-0708. ; 2013:4, s. 12-23
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The crypt in Dalby as a batisterium – a digital reconstruction The article presents an example of the on-going research at Dalby in Scania, Sweden, focusing on the baptismal font and its original medieval context. The site and the current research are presented. Dalby was a medieval cathedral, Augustinian monastery and maybe also a royal manor. The crypt and font from the 12th C are presented. The architecture and functions of the crypt have changed several times since its erection. The font, when first documented in the 19th C, was standing near the altar in the eastern part of the nave. After a restoration in the 1940s it was moved to the western end of the nave. However, after a functional and iconographic analysis of the crypt and the font, the hypothesis is put forward that the font originally was positioned in the middle of the crypt. During the Early Middle Ages the crypt would have functioned as a baptismal chapel with a well to draw water from, as was most likely also the case in nearby Lund cathedral. In order to perform a deeper study on the functionality of this space during the Middle Ages, 3D technologies such as terrestrial laser scanner and image based modelling techniques have been employed. The goal of this work is the visualization of the crypt with the font in its original setting, removing later additions and adding elements that would have been present in the 12th century. The use of such methods allowed us to reconstruct in high quality and with accuracy of details an environment that does not exist any longer, moreover the possibility to visualize and analyse our interpretation of the space in three dimensions, opened new perspectives regarding the number of people on the benches and how the crypt might have functioned
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| 7. |
- Dell'Unto, Nicolo, et al.
(författare)
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Time travel using 3D-methodologies : visualizing the medieval context of a batismal font
- 2017
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Ingår i: The Archaeology of Time Travel : Experiencing the Past in the 21st Century - Experiencing the Past in the 21st Century. - 978 1 78491 500 1 - 9781784915018 ; , s. 25-46
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Bokkapitel (refereegranskat)abstract
- Time travel is often associated with popular mediation. This article demonstrates how time travel using digital visualization may also be a useful tool doing research. The case study is the medieval cathedral and monastery of Dalby in Sweden with a 12th century crypt and font. The crypt may have functioned as a baptismal chapel in the Middle Ages. Digital 3 D techniques including terrestrial laser scanner and image based modelling are used to reconstruct the original architecture of the crypt, to move back the font and to conduct simulations of the use of the space in the liturgy.
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| 8. |
- Ekberg, EwaCarin, et al.
(författare)
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Diagnostic Criteria for Temporomandibular Disorders - INfORM recommendations : Comprehensive and short-form adaptations for adolescents.
- 2023
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Ingår i: Journal of Oral Rehabilitation. - : John Wiley & Sons. - 1365-2842. ; 50:11, s. 1167-1180
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for use in adults is in use worldwide. Until now, no version of this instrument for use in adolescents has been proposed.OBJECTIVE: To present comprehensive and short-form adaptations of the adult version of DC/TMD that are appropriate for use with adolescents in clinical and research settings.METHODS: International experts in TMDs and experts in pain psychology participated in a Delphi process to identify ways of adapting the DC/TMD protocol for physical and psychosocial assessment of adolescents.RESULTS: The proposed adaptation defines adolescence as ages 10-19 years. Changes in the physical diagnosis (Axis I) include (i) adapting the language of the Demographics and the Symptom Questionnaires to be developmentally appropriate for adolescents, (ii) adding two general health questionnaires, one for the adolescent patient and one for their caregivers, and (iii) replacing the TMD Pain Screener with the 3Q/TMD questionnaire. Changes in the psychosocial assessment (Axis II) include (i) adapting the language of the Graded Chronic Pain Scale to be developmentally appropriate for adolescents, (ii) adding anxiety and depression assessment that have been validated for adolescents, and (iii) adding three constructs (stress, catastrophizing and sleep disorders) to assess psychosocial functioning in adolescents.CONCLUSION: The recommended DC/TMD, including Axis I and Axis II for adolescents, is appropriate to use in clinical and research settings. This adapted first version for adolescents includes changes in Axis I and Axis II requiring reliability and validity testing in international settings. Official translations of the comprehensive and short-form to different languages according to INfORM requirements will enable a worldwide dissemination and implementation.
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| 9. |
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| 10. |
- Golubinskaya, Veronika, 1974, et al.
(författare)
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Expression of S100A Alarmins in Cord Blood Monocytes Is Highly Associated With Chorioamnionitis and Fetal Inflammation in Preterm Infants
- 2020
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Ingår i: Frontiers in Immunology. - : Frontiers Media SA. - 1664-3224. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- Background: Preterm infants exposed to chorioamnionitis and with a fetal inflammatory response are at risk for neonatal morbidity and adverse outcome. Alarmins S100A8, S100A9, and S100A12 are expressed by myeloid cells and have been associated with inflammatory activation and monocyte modulation. Aim: To study S100A alarmin expression in cord blood monocytes from term healthy and preterm infants and relate results to clinical findings, inflammatory biomarkers and alarmin protein levels, as well as pathways identified by differentially regulated monocyte genes. Methods: Cord blood CD14+ monocytes were isolated from healthy term (n = 10) and preterm infants (<30 weeks gestational age, n = 33) by MACS technology. Monocyte RNA was sequenced and gene expression was analyzed by Principal Component Analysis and hierarchical clustering. Pathways were identified by Ingenuity Pathway Analysis. Inflammatory proteins were measured by Multiplex ELISA, and plasma S100A proteins by mass spectrometry. Histological chorioamnionitis (HCA) and fetal inflammatory response syndrome (FIRS) were diagnosed by placenta histological examination. Results: S100A8, S100A9, and S100A12 gene expression was significantly increased and with a wider range in preterm vs. term infants. High S100A8 and S100A9 gene expression (n = 17) within the preterm group was strongly associated with spontaneous onset of delivery, HCA, FIRS and elevated inflammatory proteins in cord blood, while low expression (n = 16) was associated with impaired fetal growth and physician-initiated delivery. S100A8 and S100A9 protein levels were significantly lower in preterm vs. term infants, but within the preterm group high S100A gene expression, spontaneous onset of labor, HCA and FIRS were associated with elevated protein levels. One thousand nine hundred genes were differentially expressed in preterm infants with high vs. low S100A alarmin expression. Analysis of 124 genes differentially expressed in S100A high as well as FIRS and HCA groups identified 18 common pathways and S100A alarmins represented major hubs in network analyses. Conclusion: High expression of S100A alarmins in cord blood monocytes identifies a distinct clinical risk group of preterm infants exposed to chorioamnionitis and with a fetal inflammatory response. Gene and pathway analyses suggest that high S100A alarmin expression also affects monocyte function. The connection with monocyte phenotype and inflammation-stimulated S100A expression in other cell types (e.g., neutrophils) warrants further investigation.
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| 11. |
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| 12. |
- Hongxing, Li, et al.
(författare)
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Prevalence and Treatment Need of Temporomandibular Disorders in Chinese Adolescents Compared to an Age-matched Swedish Population
- 2009
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Objective The aim of the present study was to assess the prevalence, treatment need of TMD pain and its possible association to socio-economic factors in adolescents of Xi’an, Shaanxi Province, China. Another aim was to compare the prevalence of TMD in Xi’an, China to an agematched Swedish population. Methodology Chinese adolescents aged 15 to 19 years were surveyed by questionnaire in Xi’an, China (n=5524). A two-staged stratified sampling with the school as sampling unit was used. Students the second year at selected high schools were included. An age-matched Swedish population was included using the same diagnostic criteria for TMD (n=17015) as was used in the Chinese sample (TMDs). Results TMD pain was found in 14.8% (n=817) and 5.1% (n=871) in the Chinese and Swedish samples, respectively (p<0.0001). Female subjects had significantly more TMD pain compared to males in both the Chinese (p<0.05) and the Swedish (p<0.001) samples. There was an increase of TMD pain with age. Of those with TMD pain, 47% of the Chinese adolescents reported a perceived need for treatment. Rural location of school, poor father’s education, poor economy, living outside home, poor general and oral health, and dissatisfaction with teeth were significantly positively correlated to TMDs. Conclusion There was an alarmingly high prevalence of TMD pain in Chinese adolescents.
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| 13. |
- Hongxing, L, et al.
(författare)
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Prevalence of temporomandibular disorder pain in Chinese adolescents compared to an age-matched Swedish population.
- 2016
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Ingår i: Journal of Oral Rehabilitation. - : John Wiley & Sons Ltd.. - 1365-2842 .- 0305-182X. ; 43:4, s. 241-248
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Tidskriftsartikel (refereegranskat)abstract
- This study aimed to (i) assess the prevalence and perceived need for treatment of TMD pain, and its association with socio-economic factors and gender, in adolescents in Xi᾽an, Shaanxi Province, China, and (ii) compare the prevalence and association with gender of TMD pain in Xi᾽an to an age-matched Swedish population. We surveyed Chinese adolescents aged 15 to 19 years in Xi'an, China (n = 5524), using a questionnaire with two-stage stratified sampling and the school as the sampling unit. The study included second-year students at selected high schools. It also included an age-matched Swedish population (n = 17,015) surveyed using the same diagnostic criteria for TMD pain as that used in the Chinese sample. The survey found TMD pain in 14·8% (n = 817) of the Chinese sample and 5·1% (n = 871) of the Swedish sample (P < 0·0001). Girls had significantly more TMD pain than boys in both the Chinese (P < 0·05) and Swedish (P < 0·001) samples. TMD pain increased with age in the Chinese population. Of the Chinese adolescents with TMD pain, 47% reported that they felt a need for treatment. Rural schools, low paternal education levels, poverty, living outside the home, poor general and oral health, and dissatisfaction with teeth all showed significant positive correlations with TMD pain. Prevalence of TMD pain in Chinese adolescents was significantly higher than in the Swedish sample.
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| 14. |
- Hongxing, Li, et al.
(författare)
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Validity and reliability of OIDP and OHIP-14: a survey of Chinese high school students
- 2014
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Ingår i: BMC Oral Health. - : BioMed Central. - 1472-6831. ; 14:158, s. 1-10
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Tidskriftsartikel (refereegranskat)abstract
- Background: To determine the impact of oral diseases on everyday life, measures of oral quality of life are needed. In complementing traditional disease-based measures, they assess the need for oral care to evaluate oral health care programs and management of treatment. To assess the reliability and validity of the Oral Impact of Daily Performance (OIDP) and the short-form Oral Health Impact Profile (OHIP-14) among high school students in Xian, the capital of Shanxi province, China. Methods: Cross-sectional one-stage stratified random cluster sample using high schools as the primary sampling unit. Students completed self-administered questionnaires at school. The survey included the OHIP-14 and OIDP inventories, translated and culturally adapted for China, and global oral health and socio-behavioral measures. Results: A total of 5,608 students participated in the study, with a 93% response rate (mean age 17.2, SD 0.8, 52% females, 45.3% urban residents). The proportion experiencing at least one impact (at any frequency) during the previous six months was 62.9% for the OHIP-14 and 45.8% for the OIDP. Cronbachs alpha measured internal consistency at 0.85 for OHIP-14 and 0.75 for OIDP while Cohens kappa varied between 0.27 and 0.58 for OHIP-14 items and between 0.23 and 0.65 for OIDP items. Kappa scores for the OHIP-14 and OIDP additive scores were 0.52 and 0.66, respectively. Both measures varied systematically and in the expected direction, with global oral health measures showing criterion validity. The correlation between OIDP and OHIP-14 was r(s) + 0.65. That both measures varied systematically with socio-behavioral factors indicates construct validity. Conclusion: Both the OIDP and OHIP-14 inventories had reasonable reliability and construct validity in relation to subjective global oral health indicators among adolescents attending high schools in China and thus appear to be useful oral health -related quality of life measures in this context. Overall, the OHIP-14 and OIDP performed equally well, although OHIP-14 had superior content validity due to its sensitivity towards less severe impacts.
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| 15. |
- Nilsson, Ing-Marie, et al.
(författare)
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Adolescents with Temporomandibular Disorder Pain : The Living with TMD Pain Phenomenon
- 2011
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Ingår i: Journal of Orofacial Pain. - : Quintessence publishing co. inc.. - 1064-6655 .- 1945-3396. ; 25:2, s. 107-116
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To acquire a deeper understanding of adolescents' experiences of living with temporomandibular disorder (TMD) pain. Methods: twenty-one adolescents with TMD pain, aged 15 to 19, were strategically selected from a group of patients referred to an orofacial pain clinic. The patients were examined and received diagnoses per the Research Diagnostic Criteria for TMD. One-on-one interviews that followed a semistructured protocol focused on the patient's experiences of living with TMD pain. The interviews were recorded and transcribed verbatim, followed by content analysis to obtain a deeper understanding of adolescents' experieces living with TMD pain. Results: Content analysis led to the overall theme "Adolescents with TMD live with recurrent pain; physical problems and daily demands form a vicious circle that causes adolescents to oscillate between hope and despondency." The latent content forming the theme is grounded in three categories that evolved from 13 subcategories. For instance, five subcategories - headache; headache on awakening; jaw and tooth pain; constant thoughts of pain; and popping, cracking, clicking, and locking - formed the category that was labeled TMD pain is recurrent. The latent interpretation, ie, the meaning, of this category was that adolescents with TMD pain constantly thought about the pain, even when it was absent. Conclussion: TMD pain is a substantial problem for affected adolescents and has consequences for all aspects of their lives. In this study, the adolescents were able to talk openly and introduce issues outside of the interview protocol. Qualitative analysis deepens our understanding of the adolescent patient with TMD pain.
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| 16. |
- Nilsson, Ing-Marie, et al.
(författare)
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Adolescents with TMD Pain : the Living with TMD Pain Phenomenon
- 2010
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Konferensbidrag (refereegranskat)abstract
- Temporomandibular disorder (TMD) pain is common among adolescents, with more girls than boys reporting pain. Studies have shovn that TMD pain in adolescents has an impact on daily living. Depressive symtoms scores, somatic complaints, and limitations in jaw function were higher in adolescents with TMD pain than in non-affected adolescents. Quantitative research observes patients on a group level. But all patients are unique and the third cornerstone in evidence-based medicine - patient values - is often neglected. patient values are the unique preferences, concerns and expectations each patient brings to a clinical encounter and which must be integrated into clinical decisions if they are to serve the patient. Qualitative research methods can contribute to our knowledge by deepening our understanding of the experiences of the individual teenager with TMD pain. Aims: To acquire a deeper understanding of adolescents' experiences of living with TMD pain. Method: Twenty-one adolescents with TMD pain, aged 15 to 19, were strategically selected from a group of patients referred to an orofacial pain clinic. The patients were examined and received diagnosis per the Research Diagnostic Criteria for Temporomandibular Disorders. One-on-one interviews that followed a semi-structured protocol focused on the patient's experiences of living with TMD pain. The interviews were recorded and transcribed verbatim, followed by content analysis. Result: Content analysis led to the overall theme "Adolescents with TMD pain live in continual pain; physical problems and daily demands form a vicious circle that causes adolescents to oscillate between hope and despondency". The manifest content formning the theme consisted of three categories that evolved from 13 subcategories. Conclusion: TMD pain is a substantial problem for affected adolescents and has consequences for their life, Qualitative analysis deepens our understanding of the adolescent patient with pain, thus making more individualized support and treatment possible.
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| 17. |
- Nilsson, Ing-Marie, et al.
(författare)
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ADOLESCENTS WITH TMD PAIN, IN SEARCH OF A DEEPER UNDERSTANDING
- 2010
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Ingår i: Abstracts of the 13th World Congress of Pain. - : IASP (International Association for the Study of Pain and Omnipress).
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Aims: The aim of this study was to acquire a deeper understanding of adolescents’ experiences of living with temporomandibular disorder (TMD) pain. Method: Twenty-one adolescents with TMD pain, aged 15 to 19, were strategically selected from a group of patients referred to an orofacial pain clinic. The patients were examined and received diagnoses per the Research Diagnostic Criteria for Temporomandibular Disorders. One-on-one interviews that followed a semi-structured protocol focused on the patient’s experiences of living with TMD pain. The interviews were recorded and transcribed verbatim, followed by content analysis to get at a deeper understanding of adolescents’ experiences living with TMD pain. Results: The content analysis led to the overall theme “Adolescents with TMD live in constant pain; physical problems and daily demands form a vicious circle that causes adolescents to oscillate between hope and despondency”. The manifest content forming the theme consisted of three categories that evolved from 13 subcategories. For instance, five subcategories - headache; headache on wake-up; jaw and tooth pain; constant thoughts of pain; and popping, cracking, clicking, and locking - evolved into the Pain is constantly present category. The meaning of this category was that the adolescents constantly thought about the pain, even when it was absent. Conclusion: TMD pain is a substantial problem for affected adolescents and has consequences for their whole life. In this study, the adolescents were able to talk openly and introduce issues outside of the interview protocol. Qualitative analysis deepens our understanding of the adolescent patient with pain, thus making more individualized support and treatment possible.
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| 18. |
- Nilsson, Ing-Marie, et al.
(författare)
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Diagnostic Criteria for Temporomandibular Disorders - INfORM recommendations : Comprehensive and short-form adaptations for children
- 2023
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Ingår i: Journal of Oral Rehabilitation. - : John Wiley & Sons. - 1365-2842 .- 0305-182X. ; 50:2, s. 99-112
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) are used worldwide in adults. Until now, no adaptation for use in children has been proposed.OBJECTIVE: To present comprehensive and short-form adaptations of Axis I and II of the DC/TMD for adults that are appropriate for use with children in clinical and research settings.METHODS: Global Delphi studies with experts in TMDs and in pain psychology identified ways of adapting the DC/TMD for children.RESULTS: The proposed adaptation is suitable for children aged 6-9 years. Proposed changes in Axis I include (i) adapting the language of the Demographics and the Symptom Questionnaires to be developmentally appropriate for children, (ii) adding a general health questionnaire for children and one for their parents, (iii) replacing the TMD Pain Screener with the 3Q/TMD questionnaire, and (iv) modifying the clinical examination protocol. Proposed changes in Axis II include (i) for the Graded Chronic Pain Scale, to be developmentally appropriate for children, and (ii) adding anxiety and depression assessments that have been validated in children, and (iii) adding three constructs (stress, catastrophizing, and sleep disorders) to assess psychosocial functioning in children.CONCLUSION: The recommended DC/TMD, including Axis I and Axis II, for children aged 6-9 years, is appropriate for use in clinical and research settings. This adapted first version for children includes changes in Axis I and Axis II changes requiring reliability and validity testing in international settings. Official translations to different languages according to INfORM requirements will enable a worldwide dissemination and implementation.
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| 19. |
- Nilsson, Ing-Marie, et al.
(författare)
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Does adolescent self-reported TMD pain persist into early adulthood? A longitudinal study
- 2020
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Ingår i: Acta Odontologica Scandinavica. - : TAYLOR & FRANCIS LTD. - 0001-6357 .- 1502-3850.
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To follow up 2209 individuals in a longitudinal study and assess self-reported TMD pain, painful and non-painful comorbid conditions, and pain-related disability. Material and methods: During 2012-2014, questionnaires were sent to 2209 eligible individuals who had been screened for TMD pain each year during 2000-2003. The two screening questions were (1) Do you have pain in the temple, face, jaw joint, or jaws once a week or more often? and (2) Do you have pain when you open your mouth wide or chew once a week or more often? If the patient answered yes to one or both of the questions, TMD pain was recorded. Non-respondents received reminders; telephone interviews were offered a randomised group. The questionnaire queried TMD pain, and painful and non-painful comorbid conditions. Results: The overall response rate was 36.5%. Individuals were placed into one of four pain groups defined by their pain experience at baseline and at the follow-up: no TMD pain (69.0%), new TMD pain (13.0%), previous TMD pain (9.9%), and persistent TMD pain (8.1%). Based on the self-report surveys, significantly more responders with TMD pain at follow-up had had pain as adolescents than not. Of adolescents with TMD pain, 45.1% had pain at follow-up as young adults, while 15.8% had pain at follow-up without a previous history of TMD pain. Individuals with persistent TMD pain had high frequencies of comorbid pains (p amp;lt; .001), 45.2% reported moderate-severe depression scores (p amp;lt; .001), and 13.0% had moderate pain-related disability (GCPS). Conclusions: Based on self-report surveys, TMD pain in adolescence appears to triple the risk of TMD pain in young adulthood, and persistent pain increased comorbid pain and psychosocial distress.
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| 20. |
- Nilsson, Ing-Marie, et al.
(författare)
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Funtaliden och Fageredsfuntarna
- 2005
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Ingår i: Medeltid i Ätradalen - en resa i fyra etapper. - 9122021159
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 21. |
- Nilsson, Ing-Marie
(författare)
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Hallandslistan i kung Valdemars jordebok : nya perspektiv på Hallands tidigmedeltida skattesystem
- 2016
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Ingår i: Mellan slott och slagg : vänbok till Anders Ödman - vänbok till Anders Ödman. - 1653-1183. - 9789189578654 ; 17, s. 191-196
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The cadastre of King Valdemar is one of the most investigated and debated written sources that survive from early medieval Denmark. In particular, the detailed list of revenue from Halland has attracted a lot of attention. Despite this, many unanswered questions still remain. This article attempts to address some of these queries.
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| 22. |
- Nilsson, Ing-Marie, et al.
(författare)
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Headache and Co-morbid Pains Associated with TMD Pain in Adolescents
- 2013
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Ingår i: Journal of Dental Research. - : Sage Publications. - 0022-0345 .- 1544-0591. ; 92:9, s. 802-807
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Tidskriftsartikel (refereegranskat)abstract
- This case-control study evaluated the association of headache and other co-morbid pain with temporomandibular disorder (TMD) pain in adolescents and explored the temporal co-variance of headache and TMD pain. In a population-based sample of 12- to 19-year-olds, 350 patients with self-reported TMD pain and 350 healthy age- and sex-matched individuals were mailed questionnaires. Descriptive statistics, 95% CI, and OR analyses-logistic regression models with TMD pain as the outcome variable and adjusted for age and gender-were used for the analysis of individuals' responses. Headache, whether defined as once a week or more (OR = 6.6) or as moderate or severe (categorical), was significantly related to TMD pain. Severe headache (vs. mild) showed stronger associations with TMD (OR = 10.1) than between moderate and mild headache (OR = 5.5). Neck (OR = 4.0) and back (OR = 2.6) pain was also significantly related to TMD pain. When participants were grouped according to headache onset and TMD pain, the highest association between headache and TMD pain was found in the subgroup "Headache onset before TMD pain" (OR 9.4). In conclusion, headache appears to be independently and highly associated with TMD pain in adolescents. Neck pain and somatic complaints were also significantly associated with TMD pain. Headache seems to precede TMD pain in many adolescents with pain.
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| 23. |
- Nilsson, Ing-Marie
(författare)
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Härskarsymbol och högsäte - om betydelsen av västmarkeringar i romanska kyrkor
- 2003
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Ingår i: META. Medeltidsarkeologisk tidskrift.. ; :1, s. 31-49
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- While the liturgical centre of the church is the high altar in the chancel, the western part of the Romanesque church has often been ascribed a more secular character. This seems to be an area where those in power could assert their authority in a religious setting. The magnitude of these manifestations vary greatly, from the ostentatious westworks of the cathedrals and the miscellaneous forms of western towers of many ordinary country churches, down to the humble elevated western benches of the towerless houses of worship. The variation in scale and form has mostly been viewed as a consequence of varying economic resources among the builders, but in this article it is argued that different expressions were chosen because they also had different functional, social and symbolic connotations.
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| 24. |
- Nilsson, Ing-Marie, et al.
(författare)
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Impact of temporomandibular disorder pain in adolescents : differences by age and gender
- 2009
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Ingår i: Journal of Orofacial Pain. - : Quintessence. - 1064-6655 .- 1945-3396. ; 23:2, s. 115-122
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Tidskriftsartikel (refereegranskat)abstract
- AIMS: To evaluate the impact of temporomandibular disorder (TMD) pain by age and gender in adolescents, with assessments of this impact specifically on school absence, medication consumption, perceived need for treatment, jaw function limitation, depressive symptoms scores and somatic complaints, and graded chronic pain scale. METHODS: In a population-based sample, a mailed questionnaire was sent to 350 patients with self-reported TMD pain (group 1) and 350 healthy age- and sex-matched individuals (group 2) aged 12 to 19 years 2 to 4 weeks after their annual dental examination. The groups were divided into younger (age 12 to 15) and older (age 16 to 19) groups. Descriptive statistics and 95% confidence intervals were used, and chi-square and t-tests were calculated for analyzing group differences. Odds ratios were estimated using logistic regression. RESULTS: As expected, groups 1 and 2 differed significantly in most variables related to psychosocial and behavioral factors. For adolescents reporting TMD pain once a week or more, no gender or age differences in pain intensity were seen. Jaw function limitation, depressive symptoms scores, somatic complaints, graded chronic pain, and perceived need for TMD treatment were all significantly higher in girls than in boys. Older girls reported higher analgesic consumption and school absences than older boys. CONCLUSION: Girls reporting TMD pain had significantly greater impact on behavioral and psychosocial factors than boys. Almost one third of older girls, compared to one out of 10 older boys, reported school absences and analgesic consumption because of their TMD pain.
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| 25. |
- Nilsson, Ing-Marie, et al.
(författare)
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Impact of Temporomandibular Disorder Pain in Adolescents: Differences by Age and Gender
- 2009
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Ingår i: Journal of Orofacial Pain. - 1064-6655 .- 1945-3396. ; 23:2, s. 115-122
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Tidskriftsartikel (refereegranskat)abstract
- Aims: To evaluate the impact of temporomandibular disorder (TMD) pain by age and gender in adolescents, with assessments of this impact specifically on school absence, medication consumption, perceived need for treatment, jaw function limitation, depressive symptoms scores and somatic complaints, and graded chronic pain scale. Methods: In a population-based sample, a mailed questionnaire was sent to 350 patients with self-reported TMD pain (group 1) and 350 healthy age- and sex-matched individuals (group 2) aged 12 to 19 years 2 to 4 weeks after their annual dental examination. The groups were divided into younger (age 12 to 15) and older (age 16 to 19) groups. Descriptive statistics and 95% confidence intervals were used, and chi-square and t-tests were calculated for analyzing group differences. Odds ratios were estimated using logistic regression. Results: As expected, groups I and 2 differed significantly in most variables related to psychosocial and behavioral factors. For adolescents reporting TMD pain once a week or more, no gender or age differences in pain intensity were seen. Jaw function limitation, depressive symptoms scores, somatic complaints, graded chronic pain, and perceived need for TMD treatment were all significantly higher in girls than in boys. Older girls reported higher analgesic consumption and school absences than older boys. Conclusion: Girls reporting TMD pain had significantly greater impact on behavioral and psychosocial factors than boys. Almost one third of older girls, compared to one out of 10 older boys, reported school absences and analgesic consumption because of their TMD pain. J OROFAC PAIN 2009;23; 115-122
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| 26. |
- Nilsson, Ing-Marie, et al.
(författare)
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Incidence and temporal patterns of temporomandibular disorder pain among Swedish adolescents
- 2007
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Ingår i: Journal of Orofacial Pain. - : Quintessence. - 1064-6655 .- 1945-3396. ; 21:2, s. 127-32
-
Tidskriftsartikel (refereegranskat)abstract
- AIMS: To estimate the incidence of temporomandibular disorder (TMD) pain among Swedish adolescents by age and gender and to describe the temporal patterns of TMD pain.METHODS: This 3-year longitudinal study was carried out at all Public Dental Service clinics in a Swedish county from 2000 to 2003. All individuals aged 12 to 19 years in the county who visited the clinics for annual examinations were eligible for the study.RESULTS: Overall, the incidence of TMD pain among all adolescents was 2.9% annually among 2,255 participating adolescents. Incidence among girls was significantly higher than in boys, 4.5% versus 1.3%, respectively. Incidence increased with age in girls and boys, although less so in boys (3.0% to 6.9% versus 1.7% to 2.6%). These adolescents were re-examined annually for 3 years, and a fluctuating pattern of TMD pain was common. Overall, 11.4% of all subjects reported TMD pain on at least 1 occasion; 88.6% of the cohort remained pain-free. Of those reporting TMD pain, 4.7% could be defined as intermittent cases, 3.1% were single-incident cases, 0.9% were recurrent cases, and 0.9% had continuing pain for 1 or 2 years.CONCLUSION: The incidence of self-reported TMD pain among Swedish adolescents aged 12 to 19 years increased with age, particularly among girls. The pattern of pain in most adolescents fluctuated over time. Less than 1% of the cohort had continued pain over each year, and the majority of these subjects were girls.
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| 27. |
- Nilsson, Ing-Marie, et al.
(författare)
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Incidence of temporomandibular disorders and pain among adolescents in a Swedish county
- 2007
-
Ingår i: Journal of Orofacial Pain. - 1064-6655 .- 1945-3396. ; 21:2, s. 127-132
-
Tidskriftsartikel (refereegranskat)abstract
- AIMS: To estimate the incidence of temporomandibular disorder (TMD) pain among Swedish adolescents by age and gender and to describe the temporal patterns of TMD pain. METHODS: This 3-year longitudinal study was carried out at all Public Dental Service clinics in a Swedish county from 2000 to 2003. All individuals aged 12 to 19 years in the county who visited the clinics for annual examinations were eligible for the study. RESULTS: Overall, the incidence of TMD pain among all adolescents was 2.9% annually among 2,255 participating adolescents. Incidence among girls was significantly higher than in boys, 4.5% versus 1.3%, respectively. Incidence increased with age in girls and boys, although less so in boys (3.0% to 6.9% versus 1.7% to 2.6%). These adolescents were re-examined annually for 3 years, and a fluctuating pattern of TMD pain was common. Overall, 11.4% of all subjects reported TMD pain on at least 1 occasion; 88.6% of the cohort remained pain-free. Of those reporting TMD pain, 4.7% could be defined as intermittent cases, 3.1% were single-incident cases, 0.9% were recurrent cases, and 0.9% had continuing pain for 1 or 2 years. CONCLUSION: The incidence of self-reported TMD pain among Swedish adolescents aged 12 to 19 years increased with age, particularly among girls. The pattern of pain in most adolescents fluctuated over time. Less than 1% of the cohort had continued pain over each year, and the majority of these subjects were girls.
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| 28. |
- Nilsson, Ing-Marie
(författare)
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Jerusalem mitt i byn. Det tidigmedeltida kyrkobyggandet ur rituellt perspektiv.
- 2007
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Ingår i: Bebyggelsehistorisk tidskrift. - 0349-2834. ; 52, s. 33-40
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Tidskriftsartikel (refereegranskat)abstract
- The stone churches of the early medieval period are commonly supposed to have been built at the instance of society’s upper echelon, the buildingsthemselves being seen as symbolic proclamations of the social hegemony of the class concerned. The present article seeks to broaden the perspective regarding both the prime movers of church building and their motives. The building of a church required the participation of a number and variety of social groupings, and the possibility is suggested of the parish farmers, as well as the patron, having found aspects of the building project attractive. True, the building enterprise − a strain on both economic and manpower resources − can be said to confirm the fundamentally hierarchic structure of society, but at the same time it helped to reshape that structure. Church building and the liturgical practices of the Church articulated the inferior social standing of the peasants but can also be seen as part of the creation of a collective consciousness on the part of this group. The article also points to the importance of understanding church building in relation to a society infused with Christian norms and ideals. Lastly, parallels are drawn between early medieval church building and the crusades. Both were regarded as deeds conferring religious merit, both involved rallying a huge number of people in pursuit of a specific objective, to achieve which they were prepared to make a variety of sacrifices. The crusaders were intent on making their way to Jerusalem in the Holy Land, the early medieval church builders on creating their own Jerusalem back home in the village.
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| 29. |
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| 30. |
- Nilsson, Ing-Marie, et al.
(författare)
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Kyrkoarkeologin igår, idag och i morgon? En spekulativ positionsbestämning.
- 2011
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Ingår i: Medeltiden och arkeologin. Mer än sex decennier.. - 1653-1183. - 9789189578449 ; , s. 29-47
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- What is Church archaeology today, and what would we like it to be tomorrow? The occasion of the 90-year birthday of professor emeritus Erik Cinthio has afforded me the opportunity to reflect upon these two questions. Departure is taken in the 19th century, when medieval churches first became a topic of interest for researchers and architects. Church archaeology developed as a sub-discipline of art history, but gradually the focus shifted and archaeological questions came more and more in the forefront. In the early 1960s, Church archaeology became an integral part of Medieval archaeology (since 2005 Historical archaeology), a new academic discipline that was developed by professor Erik Cinthio at Lund University. In its 50-year history, Church archaeology has undergone several changes when it comes to technical developments, research focus and theoretical approach. In the 1980s and early 1990s, churches were viewed in an economic and social context as a means of analysing medieval society, and in the last decade there has been a move towards studies of more immaterial aspects, such as the religious and ideological significance of church buildings. Church archaeology is now a mature discipline with theoretical depth and broad fields of research, but it may face problems in the future if some issues are not addressed. Churches are a vital part of the national heritage, but in today's secular and multicultural society, research about churches needs to be made relevant for new categories of people. This may be achieved by recognizing the uniqueness of churches as a source material. Churches have deep connections both to history and to the present time, and they relate to many key aspects of the human existence. Also Church archaeology cannot develop in isolation. It can only be strengthened and enriched through meetings and confrontations with neighbouring disciplines such as art history, theology, ethnology and history.
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| 31. |
- Nilsson, Ing-Marie
(författare)
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Köpstad, kungamakt och kyrka - några tankar om medeltidens Laholm
- 2003
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Ingår i: Utskrift. - 1102-7290. ; 7, s. 6-25
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- The article discusses several aspects of the town Laholm in southern Halland in the Middle Ages, and it is put forward that royal influence may have been a significant factor in the urbanization process. The possible importance of the king in the introduction of the Christian faith in the Laholm area is also hinted, but the exact nature of Laholms medieval parish structure is difficult to comprehend. The development of the town church and other ecclesiastical institutions seem to indicate that the town did not experience any rapid growth during the later Middle Ages, but nevertheless remained an important local commecial centre.
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| 32. |
- Nilsson, Ing-Marie, et al.
(författare)
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Medeltidens kyrkor
- 2002
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Ingår i: Halland. Landskapets kyrkor. Forskningsprojektet Sockenkyrkorna. Kulturarv och bebyggelsehistoria.. ; , s. 22-32
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The article is a brief outline of the medieval building history of the churches of Halland.
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| 33. |
- Nilsson, Ing-Marie
(författare)
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Mellan makten och himmelriket : perspektiv på Hallands medeltida kyrkor.
- 2009
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The aim of the thesis is to discuss church building, the architectural design of Romanesque and Gothic churches and the use and symbolic interpretation of church buildings in the medieval period. It is suggested that churches were built for a variety of reasons, that the construction process may have been complicated and that the final result was not always the expected one. Many social groups were involved in the project, not only the elite. Churches may have acted as settings for the display of power, but they also facilitated the assessment and questioning of power. The church was an ambiguous building that people interpreted in different ways. The symbolic content of the church also changed over time. The mutability of the monuments is emphasized. The importance of considering the church’s religious significance is also stressed. Religion should not be viewed merely as an instrument used by the elite to promote power, but as an underlying ideology permeating the whole of society. Architecture can be viewed as an instrument to help make power more permanent and less dependent on individual agents. Churches can also be seen as venues for the staging of social encounters. The architectural design of the Romanesque church served to promote an idea of Christian authority and the universal power of the Church. It therefore acted as a suitable setting for elevating the groups whose place it was to maintain this divinely instituted regime on earth, that is to say, the clergy and the secular elite. The Gothicization of Romanesque churches meant that the character of the buildings was changed fundamentally, and that the hierarchical and aristocratic expressions were softened. The second part of the dissertation is an empirical application of some of the theoretical concepts outlined in the first part. The geographical framework is the province of Halland. The medieval churches in Halland can be considered a fairly neglected academic research subject. The thesies therefore also provides a general overwiev of the medieval church architecture in the province.
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| 34. |
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| 35. |
- Nilsson, Ing-Marie, et al.
(författare)
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Prevalence of temporomandibular pain and subsequent dental treatment in Swedish adolescents
- 2005
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Ingår i: Journal of Orofacial Pain. - : Quintessence. - 1064-6655 .- 1945-3396. ; 19:2, s. 144-150
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To assess the prevalence of temporomandibular disorder (TMD) pain in Swedish adolescents and related TMD treatment by dentists. Methods: All youth aged 12–19 years in Östergötland County were eligible to participate in the investigation, which took place at public dental clinics during annual examinations in 2000. The subjects were asked two questions: 1) Do you have pain in your temples, face, jaw joint, or jaws once a week or more? or 2) Do you have pain when you open your mouth wide or chew, once a week or more? Two hundred dental records of patients with TMD pain and 100 records of patients with documented dental caries were randomly selected from the population. A comparison of treatment for TMD pain and caries was assessed from these records. Results: Among the 28,899 youths participating, 4.2% reported TMD pain. The prevalence increased with age, and a significant difference was seen between boys (2.7%) and girls (6.0%) (P<0.001). In 43% of the patients with TMD pain, the TMD condition was noted in the record. TMD-related treatment was given to 34% of patients with TMD pain in dental clinics, whereas 100% of the patients with caries received restorative treatment. The most common treatment modalities for the TMD group were information about TMD and occlusal splints. Conclusion: The prevalence of self-reported TMD pain was relatively low, increased in age, and was more common in girls than boys. One-third of the patients with TMD pain received some form of TMD treatment in the dental clinics.
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| 36. |
- Nilsson, Ing-Marie
(författare)
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Reliability, validity, incidence and impact of temporomandibular pain disorders in adolescents
- 2007
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Tidigare epidemiologiska studier har visat att temporomandibulär dysfunktion (TMD), dvs smärt- och dysfunktionstillstånd lokaliserade till ansikte och käkar är vanligt förekommande hos barn och ungdomar. För att ge möjlighet till screening infördes i Östergötland en ny epidemiologisk variabel, TMD-S (TMD-smärta), som från år 2000 registreras på alla barn och ungdomar i åldrarna 12 - 19 i samband med den årliga undersökningen i Folktandvården. De får frågorna: ”Gör det ont i tinning, ansikte, käke, eller käkled en gång i veckan eller oftare?” och ”Gör det ont när du gapar eller tuggar, en gång i veckan eller oftare?”. Om en eller båda frågorna besvaras med ja, registreras det i journalen som TMD-S = 1. Besvaras frågorna med nej registreras TMD-S = 0. Avhandlingen omfattar fyra delarbeten där det övergripande syftet varit att studera tillförlitligheten av själv-rapporterad TMD smärta hos ungdomar. Vidare var syftet att utvärdera prevalens (förekomst) och incidens (nyinsjuknande) av TMD smärta, samt vad smärtan får för konsekvenser för dem som drabbas. Förekomsten av TMD-smärta hos ungdomar var 4,2%. Det var signifikant vanligare hos flickor än pojkar och ökade med stigande ålder. En genomgång av 200 journalkopior visade att 29% av ungdomar med TMD-smärta fick någon form av behandling inom allmäntandvården. De vanligaste behandlingarna var bettskena, 12%, följt av information 10%. Av ungdomarna med TMD-smärta remitterades 5% till specialisttandvården. Betyder självrapporterad TMD-smärta att man har en smärtdiagnos? I det andra delarbetet undersöktes tillförlitligheten, dvs. reliabilitet och validitet, hos den epidemiologiska variabeln. 120 ungdomar, 60 med själv-rapporterad TMD-smärta och 60 kontrollpatienter deltog i studien. En klinisk undersökning visade att de flesta ungdomarna i TMD-gruppen hade en diagnos enligt Research Diagnostic Criteria for TMD, (RDC/TMD), vanligast var muskelrelaterad (myofasciell) smärta. Majoriteten av ungdomarna angav att de hade ett subjektivt behov av behandling. Ungdomarna följdes longitudinellt och för åren 2001-2003 var det sammanlagda årliga nyinsjuknandet 2,9% bland de 2.255 ungdomar som undersöktes och registrerades varje år. Det var signifikant högre för flickorna, än för pojkarna. Incidensen ökade med stigande ålder, dock mest för flickorna. Man kunde också se ett mönster där TMD-smärtan fluktuerade över tiden. För att utvärdera skillnader i smärtbeteende, käkfunktion och psykosocialt status skickades ett frågeformulär till 350 konsekutiva patienter med TMD-smärta i åldrarna 12-19 år och 350 kontrollpatienter. Resultaten visade att ungdomarna i TMD-gruppen oftare hade återkommande smärta på flera ställen i kroppen. Flickor över lag rapporterade signifikant mer begränsningar i käkfunktionen, hade högre depressionspoäng och ett större subjektivt vårdbehov än pojkar. Nästan en tredjedel av de äldsta flickorna, jämfört en av tio av de äldre pojkarna rapporterade skolfrånvaro och analgetikakonsumtion p.g.a. TMD smärta. Sammanfattningsvis visar studierna att TMD-smärta är vanligare hos flickor än pojkar, och ökar med stigande ålder. Smärtan visar ett fluktuerande mönster och av dem som har mest återkommande och ihållande besvär är de allra flesta flickor. TMD-smärta tycks påverka beteende – och psykosociala faktorer i högre grad hos flickor än pojkar. De två screeningfrågorna kan med god tillförlitlighet användas för att fånga upp de ungdomar med TMD-smärta som önskar hjälp.
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| 37. |
- Nilsson, Ing-Marie, et al.
(författare)
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Temporomandibular pain in adolescents with a history of preterm birth
- 2019
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Ingår i: Journal of Oral Rehabilitation. - : John Wiley & Sons. - 1365-2842 .- 0305-182X. ; 46:7, s. 589-596
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Tidskriftsartikel (refereegranskat)abstract
- AIM: To evaluate the frequency of TMD pain among adolescents with a history of preterm birth compared to a matched control group. METHODS: A group of 192 preterm-born adolescents was followed up at the age of 17-19 years and compared to matched controls. Self-report questionnaires included screening questions about TMD pain, chronic diseases, general health, depression, anxiety, anger, antisocial behavior, and self-concept. TMD pain was defined as answering 'yes' to one or both of the following questions: "Do you have pain in the temple, face, temporomandibular joint, or jaws once a week or more?" and "Do you have pain when you open your mouth wide or chew once a week or more often?" Data analysis was performed using chi-square test and logistic regression model with likelihood ratio test. RESULTS: A TMD pain frequency of 23% of preterm-born adolescents and 26% among the controls was found, with no significant differences between the groups. Neither were there differences regarding anxiety, depression, anger, or self-confidence. Within the preterm group, adolescents with TMD pain registered tension and pain in the body, trouble sleeping, stomach pain, and feelings of hopelessness about the future. The controls with TMD pain, more reported having a bad life, feeling like a failure, and having bodily pain. Among tested background variables only TMJ locking or intermittent locking once a week or more was found to explain TMD pain in adolescents. CONCLUSION: A high frequency of TMD pain was found in both groups, one possible explanation could be TMJ dysfunction.
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| 38. |
- Nilsson, Ing-Marie, et al.
(författare)
-
The reliability and validity of self-reported temporomandibular disorder pain in adolescents
- 2006
-
Ingår i: Journal of Orofacial Pain. - : Quintessence. - 1064-6655 .- 1945-3396. ; 20:2, s. 138-44
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Tidskriftsartikel (refereegranskat)abstract
- AIMS: To evaluate the reliability and validity of self-reported pain associated with temporomandibular disorders (TMD) in adolescents and to determine how this validity may change over time. The authors' hypothesis was that self-reported pain can be used to reliably and accurately detect adolescents with TMD pain.METHODS: One hundred twenty adolescents, 60 with self-reported TMD pain and 60 age- and gender-matched controls without TMD pain, were examined twice. At the first examination at a Public Dental Service clinic, self-reported TMD pain was recorded for each patient. At the second examination, a clinical examination was completed, blind to the patients' self-report of pain symptoms, after which self-reported TMD pain was again recorded. The clinical examination was based upon the Research Diagnostic Criteria for TMD (RDC/TMD). Self-reported TMD pain in this investigation was based upon the subjects' responses to 2 questions: (1) Do you have pain in your temples, face, temporomandibular joint (TMJ), or jaws once a week or more? and (2) Do you have pain when you open your mouth wide or chew once a week or more?RESULTS: Test-retest reliability of .83 (kappa) was found for the 2 questions. The sensitivity was .98 (95% CI, .90 to 1.0) and specificity was .90 (95% CI, .81 to .95) for comparison of assessments made on the same day. Sensitivity was .96 (95% CI, .85 to .99) and specificity .83 (95% CI, .72 to .90) for assessments made 2 to 4 weeks apart.CONCLUSION: Very good reliability and high validity were found for the self-reported pain questions. A short time interval between the screening question and examination slightly increased the accuracy of the measure. In adolescent populations, the questions in this study can be used to screen for TMD pain.
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| 39. |
- Nilsson, Ing-Marie, et al.
(författare)
-
Treatment Seeking and Self-Constructed Explanations of Pain and Pain management Strategies Among Adolescents with Temporomandibular Disorder Pain
- 2016
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Ingår i: Journal of Oral & Facial Pain Headache. - Hanover Park, IL, United States : Quintessence. - 2333-0376 .- 2333-0384. ; 30:2, s. 127-133
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Forskningsöversikt (refereegranskat)abstract
- Aims: To explore adolescents' explanations of their temporomandibular disorder (TMD) pain, their pain management strategies for TMD pain, and their treatmentseeking behavior. Methods: One-on-one interviews were conducted with 21 adolescents aged 15 to 19 years old who had TMD pain and followed a semistructured interview guide. Subjects were strategically selected from patients referred to orofacial pain clinic. All participants had been examined and received a pain diagnosis based on the Research Diagnostic Criteria for TMD. The interviews focused on the adolescents' experiences of TMD pain, their strategies for handling pain, and how they seek care. The interviews were recorded, transcribed verbatim, and analyzed using qualitative manifest content analysis. Results: Qualitative manifest content analysis revealed two categories: (1) self-constructed explanations, with three subcategories (situation-based explanatory model, physical/bilogic model, and psychological explanatory model); and (2) pain management strategies, with four subcategories (social support, treatment, relaxation/rest, and psychological strategies). Adolescents used physical activities and psychological and pharmacologic treatment to manage pain. Reasons for seeking treatment were to be cured, to obtain explanation for their pain, and because their symtoms bother others. Conclusion: Adolescents living with TMD pain develop self-constructed explanations and pain management strategies. With access to these descriptions, dentists can be better prepared to have a dialouge with their adolescent patients about their own explanations of pain, the nature of pain, and in wich sitations the pain appears. Dentists can also explore adolescent patients' pain management stategies and perhaps also suggest new treatment stategies at an earlier stage.
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| 40. |
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| 41. |
- Rongo, Roberto, et al.
(författare)
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Diagnostic criteria for temporomandibular disorders (DC/TMD) for children and adolescents : An international Delphi study—Part 1‐Development of Axis I
- 2021
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Ingår i: Journal of Oral Rehabilitation. - : John Wiley & Sons. - 1365-2842 .- 0305-182X. ; 48:7, s. 836-845
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Tidskriftsartikel (refereegranskat)abstract
- AIM: To develop new instruments and to adapt the diagnostic criteria for temporomandibular disorders (DC/TMD) for the evaluation of TMD in children and adolescents.METHOD: A modified Delphi method was used to seek international consensus among TMD experts. Fourteen clinicians and researchers in the field of orofacial pain and TMD worldwide were invited to participate in a workshop initiated by the International Network for Orofacial Pain and Related Disorders Methodology (INfORM scientific network) at the General Session of the International Association for Dental Research (IADR, London 2018), as the first step in the Delphi process. Participants discussed the protocols required to make physical diagnoses included in the Axis I of the DC/TMD. Thereafter, nine experts in the field were added, and the first Delphi round was created. This survey included 60 statements for Axis I, and the experts were asked to respond to each statement on a five-item Likert scale ranging from "Strongly disagree" to "Strongly agree". Consensus level was set at 80% agreement for the first round, and at 70% for the next.RESULTS: After three rounds of the Delphi process, a consensus among TMD experts was achieved and two adapted DC/TMD protocols for Axis I physical diagnoses for children and adolescents were developed.CONCLUSION: Through international consensus among TMD experts, this study adapted the Axis I of the DC/TMD for use in evaluating TMD in children and adolescents.
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| 42. |
- Rongo, Roberto, et al.
(författare)
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Diagnostic criteria for temporomandibular disorders in children and adolescents: An international Delphi study-Part 2-Development of Axis II
- 2022
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Ingår i: Journal of Oral Rehabilitation. - : WILEY. - 1365-2842 .- 0305-182X. ; 49:5, s. 541-552
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Tidskriftsartikel (refereegranskat)abstract
- Background Unlike the psychosocial assessment established for adults in the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD), a standardised psychosocial assessment for children and adolescents with TMD complaints has not yet been established. Objectives To develop a new standardised instrument set to assess the psychosocial functioning in children and adolescents by adapting the psychosocial status and pain-related disability (Axis II) of the adult DC/TMD and by including new instruments. Methods A modified Delphi method was used to survey 23 international TMD experts and four international experts in pain-related psychological factors for consensus regarding assessment tools for psychosocial functioning and pain-related disability in children and adolescents. The TMD experts reviewed 29 Axis II statements at round 1, 13 at round 2 and 2 at round 3. Agreement was set at 80% for first-round consensus level and 70% for each of the second and third rounds. The psychological experts completed a complementary Delphi survey to reach a consensus on tools to use to assess more complex psychological domains in children and adolescents. For the psychological experts, the first round included 10 open-ended questions on preferred screening tools for depression, anxiety, catastrophising, sleep problems and stress in children (ages 6-9 years old) and adolescents (ages 10-19 years old) as well as on other domains suggested for investigation. In the second round, the psychological experts received a 9-item questionnaire to prioritise the suggested instruments from most to least recommended. Results The TMD experts, after three Delphi rounds, reached consensus on the changes of DC/TMD to create a form to evaluate Axis II in children and adolescents with TMD complaints. The psychological experts added tools to assess depression and anxiety, sleep disorders, catastrophising, stress and resilience. Conclusion Through international expert consensus, this study adapted Axis II of the adult DC/TMD to assess psychosocial functioning and pain-related disability in children and adolescents. The adapted Axis II protocols will be validated in the target populations.
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| 43. |
- Sjöberg, Carina, 1964-
(författare)
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Barncentrerat förhållningssätt i perioperativ vård
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Bakgrund: Barns möjligheter att involveras i den perioperativa vårdkontexten kan förbättras med ett barncentrerat förhållningssätt. För att uppnå detta behöver hänsyn både tas till att barn är beroende av sin familj och att de som enskilda individer ska involveras och vara medaktörer i sin vård. Barns involvering i den perioperativa vården har många fördelar. Det bidrar till minskad oro och rädsla och att barnet kan stärka sin kompetens och bli behandlad med respekt. Barn upplever dock att det är svårt för dem att vara delaktiga och att ha kontroll i den främmande och skrämmande perioperativa sjukhusmiljön. Barns möjligheter att vara delaktiga i den perioperativa vården är därför beroende av föräldrar och hälso-och sjukvårdspersonal liksom rutiner och fördelning av resurser i vården. Det är därför viktigt att de vuxna som ska stödja barnen har förståelse för att barn är unika och uppfattar saker ur sitt eget perspektiv baserat på sina erfarenheter.Syfte: Det övergripande syftet med avhandlingen var att öka förståelsen för vad ett barncentrerat förhållningssätt innebär inom perioperativ vård - utifrån barn, föräldrars och ett organisatoriskt perspektiv. Metod: I delarbete I användes en deskriptiv kvalitativ design med intervjuer av 10 barn (8 till 11år). Delarbete II hade en explorativ kvalitativ design med intervjuer av 20 föräldrar. Delarbete I och II analyserades med kvalitativ innehållsanalys för att beskriva barn och föräldrars erfarenheter av delaktighet i pediatrisk perioperativ vård. I delarbete III användes en explorativ kvalitativ design med intervjuer av hälso-och sjukvårdpersonal. Analysen genomfördes med grundad teori för att utforska processen av ett organisatoriskt förbättringsarbete för barn som genomgick sedering för intratekal cytostatikabehandling. I delarbete IV användes en deduktiv kvantitativ design med registerdata och analys med deskriptiv statistik för att beskriva tidsintervall och använd Propofol-dos vid sedering för intratekal cytostatikabehandling i tre olika miljöer. Resultat: Delarbete I visar att barns upplevelse av delaktighet påverkats av hur de informerats inför och under det perioperativa vårdförloppet. Vidare har relationen till hälso-och sjukvårdspersonalen haft betydelse för barns möjligheter att involveras i beslutsfattande. Dessutom har sjukhusmiljön, väntetid och möjligheter att förströ sig haft inflytande på barns upplevelse av delaktighet. I delarbete II beskriver huvudkategorin att föräldrars delaktighet i pediatrisk perioperativa vård vid dagkirurgi betydde ”Having strength to participate despite an increased vulnerability ”. Tillsammans med underkategorierna; få information om vad som ska hända, att bli sedd som en resurs och att få tillgång till miljön. I delarbete III beskriver “The theory of a shielding place” hur hälso-och sjukvårdspersonalen med ett barncentrerat förhållningssätt utförde proceduren sedering för intratekal cytostatikabehandling på barnavdelningen. Resultatet i delarbete IV kontrollerar och kvantifierar objektivt delar av resultatet från delarbete III. Genom att visa att när proceduren utförs på barnavdelningen minskas väntetid och tidsåtgång för proceduren som helhet. Konklusion: För barn och föräldrar som genomgår dagkirurgi har information, samspelet med hälso-och sjukvårdspersonalen och miljön haft betydelse för upplevelsen av delaktighet. Ur ett organisatoriskt perspektiv påverkas ett barncentrerat förhållningssätt av de rutiner som har betydelse för hur barn och föräldrar förbereds. Resurser och rutiner påverkar också om sjukhusmiljöer är anpassade för barn, väntetid och tidsåtgång, liksom relationer mellan barn och hälso-och sjukvårdspersonal.
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| 44. |
- Srimanee, Artita
(författare)
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Peptide-based delivery to glioblastoma cells studied by the blood-brain barrier model
- 2016
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Crossing the blood-brain barrier (BBB) is a great challenge for delivery of highly charged macromolecules such as nucleic acids and proteins to the brain. Cell-penetrating peptides (CPPs) are promising vectors to deliver various cargoes ranging from small molecules to large molecules such as antibodies, proteins, and nucleic acids. The BBB limits the passage of all large molecules to central nervous system (CNS), thus, CPP is a potential vector to use for oligonucleotide delivery across the BBB. In paper I, various CPPs were covalently conjugated with two different glioma-targeting peptides, glioma-homing peptide (gHo) and angiopep-2 (ANG). PepFect 32 (PF32), a conjugation between truncated PepFect 14 and ANG, was the most efficient vector to deliver plasmid DNA (pDNA) across a setup in vitro model of the BBB and showed the highest transfection in glioma cells. LRP-1 receptors, which are over-expressed in brain endothelial cells and glioma cells, were speculated to mediate the transcytosis of PF32:pDNA complexes across the BBB model since the ANG could target to LRP-1. In paper II, scavenger receptors class A and B (SCARA3, SCARA5, and SR-BI) were found to be expressed in the brain endothelial cells. Inhibition of these scavenger receptors led to a reduction of the transfection of PF32:pDNA complexes in the brain endothelial cells. Therefore, in the BBB model scavenger receptors also played a vital role as well as LRP-1 in the transport of oligonucleotides in the complex with peptide-based vector PF32.In conclusion, PF32 is a potential vector to deliver pDNA across the BBB model and target to the glioma cells. The complexes of PF32:pDNA transport across the brain endothelial cells via receptor-mediated endocytosis pathway recognized by scavenger receptors and LRP-1. To improve the specificity and enhance the transport into the brain, the brain-homing devices are considered as a promising strategy for CNS drug delivery.
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| 45. |
- Svensson, Mattias, 1982, et al.
(författare)
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Fms-like tyrosine kinase 3 ligand controls formation of regulatory T cells in autoimmune arthritis.
- 2013
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Ingår i: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 8:1
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Tidskriftsartikel (refereegranskat)abstract
- Fms-like tyrosine kinase 3 ligand (Flt3L) is known as the primary differentiation and survival factor for dendritic cells (DCs). Furthermore, Flt3L is involved in the homeostatic feedback loop between DCs and regulatory T cell (Treg). We have previously shown that Flt3L accumulates in the synovial fluid in rheumatoid arthritis (RA) and that local exposure to Flt3L aggravates arthritis in mice, suggesting a possible involvement in RA pathogenesis. In the present study we investigated the role of Flt3L on DC populations, Tregs as well as inflammatory responses in experimental antigen-induced arthritis. Arthritis was induced in mBSA-immunized mice by local knee injection of mBSA and Flt3L was provided by daily intraperitoneal injections. Flow cytometry analysis of spleen and lymph nodes revealed an increased formation of DCs and subsequently Tregs in mice treated with Flt3L. Flt3L-treatment was also associated with a reduced production of mBSA specific antibodies and reduced levels of the pro-inflammatory cytokines IL-6 and TNF-α. Morphological evaluation of mBSA injected joints revealed reduced joint destruction in Flt3L treated mice. The role of DCs in mBSA arthritis was further challenged in an adoptive transfer experiment. Transfer of DCs in combination with T-cells from mBSA immunized mice, predisposed naïve recipients for arthritis and production of mBSA specific antibodies. We provide experimental evidence that Flt3L has potent immunoregulatory properties. Flt3L facilitates formation of Treg cells and by this mechanism reduces severity of antigen-induced arthritis in mice. We suggest that high systemic levels of Flt3L have potential to modulate autoreactivity and autoimmunity.
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| 46. |
- Vijayaraghavan, Balaje
(författare)
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Identification and characterization of nuclear envelope protein interactions
- 2015
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Licentiatavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The Nuclear envelope which surrounds the chromatin of eukaryotic cells contains more than a hundred transmembrane proteins. Mutations in some genes encoding nuclear envelope proteins give rise to human diseases including neurological disorders. The function of many nuclear envelope proteins is not well established. This is partly because nuclear envelope proteins and their interactions are difficult to study due to the inherent resistance to extraction of nuclear envelope proteins. We have developed a novel method called MCLIP, to identify interacting partners of nuclear envelope proteins in live cells. Using MCLIP, we found three new binding partners of the inner nuclear membrane protein Samp1: the intermediate filament protein Lamin B1, the LINC complex protein Sun1 and the G-protein Ran. Furthermore, using in vitro studies, we show that Samp1 binds both Emerin and Ran directly. We have also studied the interaction between Samp1 and Ran in detail.
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| 47. |
- Wahlund, Kerstin, et al.
(författare)
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Internet-based treatment for adolescents with symptomatic temporomandibular joint disc displacement with reduction : A randomized controlled clinical trial
- 2021
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Ingår i: Acta Odontologica Scandinavica. - : Taylor & Francis Group. - 0001-6357 .- 1502-3850. ; 79:6, s. 473-481
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To evaluate treatment outcome of a jaw exercise (JE) intervention program combined with an information/counselling program (IC) vs. information/counselling alone.Materials and methods: A clinical sample of 83 adolescents, experiencing painful clicking or catching/locking of the jaw, and diagnosed with symptomatic disc displacement with reduction according to RDC/TMD, were randomly assigned to JE/IC or IC program. Both programs were internet-delivered. The adolescents were examined clinically at baseline, at a 2-month mid-evaluation, and at 4months posttreatment by examiners blinded to which programs the adolescents were assigned to.Results: The JE/IC group showed significantly more improvements of painful catching/locking (p =.017), eating ability (p =.006) and of their jaw function limitation (p =.026) compared to the IC group. Significantly more adolescents in the JE/IC group also reported a ≥50% improvement of the catching/locking of the jaw with pain (p =.024) and for eating ability (p =.034) based on a severity index. Treatment method credibility and satisfaction were also significantly higher in the JE/IC group.Conclusion: The internet-delivered JE/IC program showed a better outcome compared to IC alone. The former is thus a feasible and cost-effective treatment for adolescents with symptomatic disc displacement with reduction.
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| 48. |
- Wahlund, Kerstin, et al.
(författare)
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Treating temporomandibular disorders in adolescents : a randomized, controlled, sequential comparison of relaxation training and occlusal appliance therapy
- 2015
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Ingår i: Journal of Oral & Facial Pain and Headache. - : Quintessence. - 2333-0384. ; 29:1, s. 41-50
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Tidskriftsartikel (refereegranskat)abstract
- AIMS: To compare the effects of occlusal appliance therapy (OA) and therapist-guided relaxation training (RT) on temporomandibular disorder (TMD) pain in adolescents, thereby replicating a previous randomized controlled trial, and to explore whether additional therapy administered in a crossover sequential design improves treatment outcomes. METHODS: The study involved 64 adolescents, aged 12 to 19 years, experiencing TMD pain at least once a week and diagnosed with myofascial pain in accordance with the Research Diagnostic Criteria for TMD. For phase 1 of the study, subjects were randomly assigned to OA or RT; nonresponders were offered the other treatment in phase 2. Self-reports of TMD pain and clinical assessments were performed before and after treatment in each phase and 6 months after the last treatment phase. Differences in outcomes between treatment groups across the different phases were analyzed by analysis of covariance (ANCOVA), and for differences in proportions, the chi-square test was used. RESULTS: After phase 1, a significantly higher proportion of adolescents treated with OA (62.1%) than those treated with RT (17.9%) responded to treatment, defined as a subjective report of "Completely well/Very much improved" or "Much improved." Similar differences in self- report of treatment effect occurred after phase 2. About two-thirds of all adolescents in both phases reported such an improvement level at the 6-month follow-up, including a somewhat higher proportion of phase 1 responders (79.2%) than phase 1 nonresponders (60%). CONCLUSION: The findings suggest that, for adolescents with TMD pain, use of standardized clinical treatment with OA is more effective than RT on self-evaluation of treatment improvement. For nonresponders, subsequent crossover treatment might be useful to improve subjective TMD pain.
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| 49. |
- Ödman, Anders, et al.
(författare)
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Från byggnadsträl till järnskattebonde. Arbetskraftsrekrytering och produktionslokalisering i det medeltida Skåne
- 2013
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Ingår i: Berättelser från markerna: en antologi om järn, skog och kulturarv. - 9789197117746 ; , s. 145-156
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- The article is about the labours, dealing with stone transport, quarrying and building of the big chatedrals in Skåne. How they later are emploied in constructing the Parrish churches and after that are found as colonising and iron producing farmers in the waste land of northern Skåne. The thesis is that it is a big group of slaves, imported from the west slavonic area. First used as Construction workers and finaly found as the kings farmers. A great and succesfull integration Project.
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| 50. |
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