| 1. |
- Almobarak, Bilal, et al.
(författare)
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Exposure to nonanoic acid alters small intestinal neuroendocrine tumor phenotype
- 2023
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Ingår i: BMC Cancer. - : Springer Science and Business Media LLC. - 1471-2407. ; 23:1
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundSmall intestinal neuroendocrine tumors (SI-NET) are highly differentiated and genetically stable malignant tumors, yet they often present with advanced metastatic spread at the time of diagnosis. In contrast to many other types of malignant tumors, primary SI-NET are often asymptomatic and typically smaller in size compared to adjacent lymph node metastases. This study explores the hypothesis that stimulating the chemosensing olfactory receptor 51E1 (OR51E1) decreases SI-NET proliferation suggesting a mechanism that explains a difference in proliferative rate based on tumor location.MethodsClinical data was used to address difference in tumor size depending on location. A SI-NET tissue microarray was used to evaluate expression of OR51E1 and olfactory marker protein (OMP). Primary cultured tumor cells from 5 patients were utilized to determine the effect of OR51E1 agonist nonanoic acid on metabolic activity. The SI-NET cell line GOT1 was used to determine effects of nonanoic acid on the transcriptome as well as long-term effects of nonanoic acid exposure with regards to cell proliferation, serotonin secretion, alterations of the cell-cycle and morphology.ResultsTumor size differed significantly based on location. OR51E1 and OMP were generally expressed in SI-NET. Primary SI-NET cells responded to nonanoic acid with a dose dependent altered metabolic activity and this was replicated in the GOT1 cell line but not in the MCF10A control cell line. Nonanoic acid treatment in GOT1 cells upregulated transcripts related to neuroendocrine differentiation and hormone secretion. Long-term nonanoic acid treatment of GOT1 cells decreased proliferation, induced senescence, and altered cell morphology.ConclusionOur results raise the possibility that exposure of intraluminal metabolites could represent a mechanism determining aspects of the SI-NET tumor phenotype. However, we could not causally link the observed effects of nonanoic acid exposure to the OR51E1 receptor.
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| 2. |
- Eriksson, Katarina
(författare)
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Finance and Supply Chain Management : Coordination of a Dyadic Supply Chain through Application of Option Contracts
- 2019
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The purpose of this dissertation is to study the relationship between dyadic supply chain flexibility and dyadic supply chain profitability.In today’s global environment, competition is no longer limited to companies but has evolved to supply chains. Supply disruption, lead time uncertainty and stochastic demand can result in costly inefficiencies of up to 40% when companies are trying to coordinate ordering and production. A dyadic supply chain competing in a global economy cannot afford to end up with a 40% smaller share of the pie.This thesis applies theory and instruments from finance, specifically portfolio theory and real options theory when applying option contracts to create flexibility in a dyadic supply chain.The methodology applied was to conduct an initial literature review of prior research to establish research gaps (first paper). This resulted in the development of an algorithm (second paper) combining the base stock model and the option mechanism to create flexibility for an OEM and supplier to coordinate ordering and production bilaterally in a multi-period setting. In the third paper the algorithm was applied to a case study using data from two companies, which resulted in the algorithm being tested and validated. Furthermore, option contract theory was integrated with dyadic supply chain practise while Fisher portfolio paradox was addressed.The dissertation contributes in the following areas: the empirical contribution is evidence of the relationship between dyadic supply chain flexibility and profitability using quantitative data from two companies.The methodological contribution is a method for the objective valuation of dyadic supply chain flexibility and the measurement of profitability, by valuing the option contract.The theoretical contribution is achieved through the integration of portfolio and option theory into SCM while addressing Fisher’s portfolio paradox.The practical contribution is an algorithm that creates flexibility for an OEM and asupplier to coordinate ordering and production bilaterally and maintain its collaborative advantage when competing in a global economy, thus avoiding ending up with a 40% smaller share of the pie. In addition, this dissertation advances this topic in SCM into a quantitatively measurable theory.
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| 3. |
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| 4. |
- Jonnergård, Karin, 1957-, et al.
(författare)
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Information environment : an exploration and clarification of the concept based on prior literature
- 2020
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Ingår i: Advances in Accounting. - : Elsevier. - 0882-6110. ; 50, s. 1-11
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Tidskriftsartikel (refereegranskat)abstract
- In the accounting and finance literature, the concept of the information environment (IE) is widely used, but its meaning varies across different articles. Given the considerable presence of the IE concept, it seems relevant to clarify the concept and allow a clearer path forward for future research. With this ambition, this paper reviews articles that apply the concept of IE. Our sample consists of 248 articles published within the accounting and finance field between 2000 and 2017. We confirm an increasing trend in the use of the concept over time and discuss the lack of distinctness in the concept's general meaning. Several definitions of IE appear parallel to one another in the literature; in many cases, these definitions are also inconsistent. To analyze the concept, we use a two-step approach with the following subordinated aims: 1) to identify and clarify different types of IE, and 2) to identify and clarify the components that constitute the firm's IE. We find that the description preceding the term IE signals a border between different types of information or between different societal levels of IE. Also, the concept appears as a “system concept,” and its inclusion of different actors, the relations among these actors, and the effect of these relations on information asymmetry are core aspects that need to be described in future research.
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| 5. |
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| 6. |
- Knauss, Eric, 1977, et al.
(författare)
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Supporting Continuous Integration by Code-Churn Based Test Selection
- 2015
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Ingår i: RCoSE - 2nd International Workshop on Rapid Continuous Software Engineering @ ICSE 2015 Florence, Italy.
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Continuous integration promises advantages in large-scale software development by enabling software development organizations to deliver new functions faster. However, implementing continuous integration in large software development organizations is challenging because of organizational, social and technical reasons. One of the technical challenges is the ability to rapidly prioritize the test cases which can be executed quickly and trigger the most failures as early as possible. In our research we propose and evaluate a method for selecting a suitable set of functional regression tests on system level. The method is based on analysis of correlations between test-case failures and source code changes and is evaluated by combining semi-structured interviews and workshops with practitioners at Ericsson and Axis Communications in Sweden. The results show that using measures of precision and recall, the test cases can be prioritized. The prioritization leads to finding an optimal test suite to execute before the integration.
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| 7. |
- Knutsson, Eva Smith, et al.
(författare)
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Genital Chronic Graft-versus-Host Disease in Females: A Cross-Sectional Study
- 2014
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Ingår i: Biology of Blood and Marrow Transplantation. - : Elsevier BV. - 1083-8791 .- 1523-6536. ; 20:6, s. 806-811
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Tidskriftsartikel (refereegranskat)abstract
- Using the National Institutes of Health (NIH) consensus criteria for chronic graft-versus-host disease (cGVHD), we assessed the prevalence, symptoms, and clinical signs of female genital cGVHD in a cross-sectional population-based study. Forty-two women were evaluated at a median of 80 months (range, 13 to 148 months) after undergoing hematopoietic stem cell transplantation (HSCT). Medical history, ongoing medications, and genital signs and symptoms were recorded. Gynecologic examination for the diagnosis and clinical scoring of genital cGVHD was combined with clinical scoring of extragenital cGVHD for the estimation of each patient’s global cGVHD score. Biopsy specimens from the genital mucosa were obtained from 38 patients. Genital cGVHD was diagnosed in 22 of 42 patients (52%). Its presence was associated with systemic corticoid steroid treatment of extragenital cGVHD (P .001), older age (P .07), and HSCT from a sibling donor (P .002). Five patients had isolated genital cGVHD. Dryness, pain, smarting pain (P < .05 for all), and dyspareunia (P .001) were observed more frequently in the women with genital cGVHD. Twelve patients had advanced genital cGVHD (clinical score 3), which was the main factor explaining the high rate (15 of 42) of severe global cGVHD. The rate of genital cGVHD was similar (P .37) in patients with a follow-up of 80 months (10 of 22) and those with a follow-up of <80 months (12 of 20). We found no convincing relationship between clinical diagnosis and histopathological assessment of mucosal biopsy specimens. In our group of women with a long follow-up after HSCT, genital cGVHD was common and in many cases incorrectly diagnosed. Genital cGVHD causes genital symptoms and affects sexual life, and may present without any other cGVHD, warranting early and continuous gynecologic surveillance in all women after HSCT.
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| 8. |
- Lennartsson, Otto, et al.
(författare)
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Case Report : Bilateral Epiphysiodesis Due to Extreme Tall Stature in a Girl With a De Novo DNMT3A Variant Associated With Tatton-Brown-Rahman Syndrome
- 2021
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Ingår i: Frontiers in Endocrinology. - : Frontiers Media S.A.. - 1664-2392. ; 12
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To present a rare clinical case of a patient with Tatton-Brown-Rahman syndrome and the outcome of tall stature management with bilateral epiphysiodesis surgery at the distal femur and proximal ends of tibia and fibula.Study Design: Clinical case report.Results: This is a 20-year-old female with a history of proportional tall stature, developmental psychomotor and language delay with autism spectrum behavior and distinctive facial features. At 12 years and 2 months of age she was in early puberty and 172.5 cm tall (+ 2.8 SDS) and growing approximately 2 SDS above midparental target height of 173 cm (+ 0.9 SDS). A bone age assessment predicted an adult height of 187.1 cm (+3.4 SDS). To prevent extreme tall stature, bilateral epiphysiodesis surgery was performed at the distal femur and proximal ends of tibia and fibula at the age of 12 years and 9 months. After the surgery her height increased by 12.6 cm to 187.4 cm of which approximately 10.9 cm occurred in the spine whereas leg length increased by only 1.7 cm resulting in a modest increase of sitting height index from 50% (-1 SDS) to 53% (+ 0.5 SDS). Genetic evaluation for tall stature and intellectual disability identified a de novo nonsense variant in the DNMT3A gene previously associated with Tatton-Brown-Rahman syndrome.Conclusion: Tatton-Brown-Rahman syndrome should be considered in children with extreme tall stature and intellectual disability. Percutaneous epiphysiodesis surgery to mitigate extreme tall stature may be considered.
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| 9. |
- Lennartsson, Otto, et al.
(författare)
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Discordance Between Stimulated and Spontaneous Growth Hormone Levels in Short Children Is Dependent on Cut-Off Level and Partly Explained by Refractoriness
- 2020
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Ingår i: Frontiers in Endocrinology. - : Frontiers. - 1664-2392. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- Background: A growth hormone (GH) stimulation test is the recommended method for evaluating GH levels in children with possible GH deficiency (GHD). However, serial measurements of nocturnal spontaneous GH secretion are also performed. Divergent results from these tests have been reported, but with variable frequencies.Objectives: To investigate whether performing one or two GH tests is associated with the probability to diagnose a child with GHD; the frequency of divergent results in the arginine-insulin tolerance test (AITT) and the nocturnal spontaneous test using different cut-off levels, and whether refractoriness may explain some of the discordance.Methods: In a population-based setting, the medical records of all short children evaluated for possible GHD during January 1993-February 2017 were reviewed. Twenty-one patients had been evaluated with one GH test only and 102 children had been evaluated with a spontaneous nocturnal GH test followed immediately by a complete AITT. Divergent results were defined as having a pathological response on only one of the tests when using 3, 5, 7, and 10 µg/L as cut-offs for peak GH on both tests, 1.1 and 3.3 µg/L for mean nocturnal values and receiver operating characteristic curves-derived cut-offs for nocturnal values.Results: Children evaluated with one test only were more often diagnosed with GHD compared with children evaluated with both tests (48 vs. 19%, p = 0.019). Divergent results were found in 6-42% of the patients, with higher frequencies seen when higher cut-offs were applied. A higher proportion of patients with stimulated peak values ≤ 7 and ≤ 5 µg/L had a spontaneous peak within 2 h before the start of the AITT compared with patients with higher stimulated peak values (68 vs. 45%, p = 0.026, and 77 vs. 48%, p = 0.033, respectively).Conclusions: Divergent results between AITT and nocturnal spontaneous secretion are common in short children, dependent on the cut-offs applied and partly due to refractoriness. Performing both tests decreases the risk of over diagnosing GHD in short children.
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| 10. |
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| 11. |
- Lennartsson, Otto, 1993-, et al.
(författare)
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Sex steroid priming decreases the frequency of divergent results between spontaneous and stimulated GH tests
- 2023
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Ingår i: Hormone Research in Paediatrics. - : S. Karger. - 1663-2818 .- 1663-2826. ; 96:Suppl. 4, s. 287-287
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Introduction: The diagnosis of growth hormone (GH) deficiency (GHD) is complicated by the low specificity of GH testing, especially in children before and during early pubertal stages. Sex steroid priming reduces false positive results in pre- and early pubertal children. However, only a small number of studies have assessed its efficacy in improving the diagnostic accuracy of GHD investigations.Aim: To evaluate the effect of sex steroid priming in GH testing on the prevalence of divergent results of spontaneous nocturnal secretion and arginine-insulin-tolerance test (AITT).Methods and Materials: This is a retrospective chart review of all 196 children investigated for GHD from January 1, 1993 until February 28, 2023 at the Department of Paediatrics, Örebro University Hospital, Örebro, Sweden. Of them 173 (89%) children had undergone both overnight GH sampling and AITT and 28 of 173 children (16%) had received estrogen priming prior to their tests. A GH peak concentration of ≥ 7.0 μg/L or more was considered normal for both tests.Results: Children receiving priming (36% girls) had a median age of 12.1 years (6.2–15.0) vs. 8.4 years (1.5 – 15.9) in children not primed (43% girls). Of the 173 children that had undergone both tests, 31 (18%) tested positive (<7.0 μg/L) on both tests, 22 (13%) tested positive on overnight sampling only, and 13 (8%) tested positive on AITT only. Of the 28 children who had received priming ,only one child had divergent results, with a positive result solely from AITT. Amongst non-primed children, 34 of 145 had divergent results with 21 (14.6%) testing positive on AITT, and 13 (9%) exhibiting a positive result on the spontaneous GH test. The frequency of divergent tests was significantly lower (p = 0.016) amongst primed children (3.6%) compared to non-primed children (23.6%).Conclusion: Our results show that sex steroid priming prio rto GHD testing with overnight sampling and AITT decreases the frequency of divergent results between the two tests and thus suggest that sex steroid priming decreases the risk of false positive results.
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| 12. |
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| 13. |
- Lyckesvärd, Madeleine Nordén, et al.
(författare)
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Linking loss of sodium-iodide symporter expression to DNA damage
- 2016
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Ingår i: Experimental Cell Research. - : Elsevier BV. - 0014-4827. ; 344:1, s. 120-131
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Tidskriftsartikel (refereegranskat)abstract
- Radiotherapy of thyroid cancer with I-131 is abrogated by inherent loss of radioiodine uptake due to loss of sodium iodide symporter (NIS) expression in poorly differentiated tumor cells. It is also known that ionizing radiation per se down-regulates NIS (the stunning effect), but the mechanism is unknown. Here we investigated whether loss of NIS-mediated iodide transport may be elicited by DNA damage. Calicheamicin, a fungal toxin that specifically cleaves double-stranded DNA, induced a full scale DNA damage response mediated by the ataxia-telangiectasia mutated (ATM) kinase in quiescent normal thyrocytes. At sublethal concentrations (< 1 nM) calicheamicin blocked NIS mRNA expression and transepithelial iodide transport as stimulated by thyrotropin; loss of function occurred at a much faster rate than after I-131 irradiation. KU-55933, a selective ATM kinase inhibitor, partly rescued NIS expression and iodide transport in DNA-damaged cells. Prolonged ATM inhibition in healthy cells also repressed NIS-mediated iodide transport. ATM-dependent loss of iodide transport was counteracted by IGF-1. Together, these findings indicate that NIS, the major iodide transporter of the thyroid gland, is susceptible to DNA damage involving ATM-mediated mechanisms. This uncovers novel means of poor radioiodine uptake in thyroid cells subjected to extrinsic or intrinsic genotoxic stress. (C) 2016 Elsevier Inc. All rights reserved.
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| 14. |
- Nilsson, Ola, 1968-
(författare)
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Förtroendeperspektiv på aktiebolagsrevision
- 2016
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This dissertation is motivated by the circumstance that theoretical discussions of statutory auditing are dominated by the principal-agent perspective. The effect of this has been so pervasive that general assumptions characterising the principal-agent perspective may have become regarded as true. On this basis, there are fears that important decisions, for example, could be made on erroneous grounds, as principal-agent perspectives essentially lack external validity. Critics have pointed out that the basic assumptions of the principalagent theoretical perspective – that individuals always act out of self-interest and that there is a constant risk of opportunism – become too general and need to be made more nuanced. It has been argued that trust, which may be regarded as a contrasting concept to self-interest and opportunism, might be integrated to support external validity. It may also be noted that this term – trust – has become a catchword for describing the significance and role of auditing in the practical discourse. These arguments support the relevance of this dissertation, where the overall purpose is to elaborate on a theoretical perspective on the statutory auditing including trust. This will contribute to explaining and understanding statutory auditing in a way that balances the currently dominant theoretical perspectives on auditing.The dissertation accomplishes this in three related ways building on three parts. The first of these aims to substantiate a theoretical proposition based on trust theory. It focuses on clarifying various dimensions of trust which may contribute to analysing the role and significance of auditing. The second is an empirical study aimed at elucidating auditing from a systems perspective and contains a historical analysis in which texts are used to reproduce and analyse some of the developments on the basis of the theoretical framework. The third is an empirical study which concerns auditing from an investors perspective. It is based on a survey of equity investors in companies listed on the Stockholm stock exchange, and also based on the theoretical framework. The two empirical studies contribute to substantiating the proposition that trust is a concept that should be integrated in theories explaining the role and function of auditing.
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| 15. |
- Nilsson, Ola, 1968-
(författare)
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Legislative Pressure and Credit Rating Agency Behaviour
- 2021
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Ingår i: Risk Governance and Control. - : Virtus InterPress. - 2077-429X .- 2077-4303. ; 11:2, s. 58-70
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Tidskriftsartikel (refereegranskat)abstract
- This study investigates whether legislative pressure influences credit rating agency (CRA) behavior. It covers a time period in which the European Union moves from exerting minimal to intense legislative pressure on CRAs, providing an almost ideal context for analyzing if and how CRAs are affected by this pressure. Two possible outcomes are discussed: 1) more timeliness in the flow of information and 2) more stickiness in the flow of information. The analysis is based on an examination of market reactions following CRA announcements between 2000 and 2019. The results show that the market reactions after CRA announcements decrease when legislative pressure increases. The interpretation is that as legislative pressure increases, the flow of information from CRAs becomes stickier. This confirms that legislative initiatives that put pressure on CRAs have an effect, evidence that legislators’ intention to change behavior by threatening or initiating new regulations works, which confirms assumptions underlying the theory of legislative threats (Halfteck, 2008). A reasonable interpretation of legislators’ push for changes in this context is that they want to see a faster flow of information. The results, however, show the opposite. A plausible explanation for this is increased caution on the part of CRAs because if in retrospect, the information in an announcement turns out to be wrong or misleading, the ensuing criticism could lead to additional pressure.
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| 16. |
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| 17. |
- Nilsson, Ola, 1968-
(författare)
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The relationship between shareholder protection through regulation and the demand for external auditor services
- 2018
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Ingår i: International Journal of Disclosure & Governance. - Basingstoke : Palgrave Macmillan. - 1741-3591 .- 1746-6539. ; 15:3, s. 162-175
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Tidskriftsartikel (refereegranskat)abstract
- Auditing is one of the most obvious corporate governance mechanisms, and auditors play one of the most central gatekeeping roles in the corporate governance system. The auditing function has typically been examined as if it is essentially independent of the legal context in which it is applied. However, some studies emphasize that the auditor’s governance role is likely dependent on the national corporate governance system in which an auditor operates. One area that has received attention is how the legal environment, including the strength of shareholder protection regulations, affects the demand for auditing. However, entirely contradictory understandings of this relationship can be derived from the literature: that these two mechanisms act as substitutes and that they act as complements. A potential explanation for this discrepancy is that prior studies use static measures of regulations as proxies for shareholder protections and proxies for auditing service demand that have been criticized for being too rough. By using the Shareholder Protection Index developed by the Centre for Business Research at Cambridge and four measures capturing nuances of auditing service demand, this study makes a novel contribution to this line of research. By using data from two countries, the UK and Sweden, that belong to different legal traditions, the analysis also tests whether this aspect has any impact on the relationship between shareholder protections and auditor demand. The analysis shows that the demand for auditor services in general is positively correlated with the level of shareholder protection imposed by regulations, i.e., these two corporate governance mechanisms are compliments. There is no support for the argument that a country’s legal origin affects this relationship. The general interpretation is that the level of shareholder protections imposed by regulations will drive the demand for auditor services and that this is the case irrespective of a country’s legal origin. This study provides in-depth knowledge on the relationship between the legal environment and the demand for auditing, offers valuable information about the impact and consequences of legal reforms and is therefore especially valuable for policymakers and academics interested in this topic.
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| 18. |
- Nyberg, Jenny, 1976, et al.
(författare)
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Glucose-dependent insulinotropic polypeptide is expressed in adult hippocampus and induces progenitor cell proliferation.
- 2005
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Ingår i: The Journal of neuroscience : the official journal of the Society for Neuroscience. - : Society for Neuroscience. - 1529-2401. ; 25:7, s. 1816-25
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Tidskriftsartikel (refereegranskat)abstract
- The hippocampal dentate gyrus (DG) is an area of active proliferation and neurogenesis within the adult brain. The molecular events controlling adult cell genesis in the hippocampus essentially remain unknown. It has been reported previously that adult male and female rats from the strains Sprague Dawley (SD) and spontaneously hypertensive (SHR) have a marked difference in proliferation rates of cells in the hippocampal DG. To exploit this natural variability and identify potential regulators of cell genesis in the hippocampus, hippocampal gene expression from male SHR as well as male and female SD rats was analyzed using a cDNA array strategy. Hippocampal expression of the gene-encoding glucose-dependent insulinotropic polypeptide (GIP) varied strongly in parallel with cell-proliferation rates in the adult rat DG. Moreover, robust GIP immunoreactivity could be detected in the DG. The GIP receptor is expressed by cultured adult hippocampal progenitors and throughout the granule cell layer of the DG, including progenitor cells. Thus, these cells have the ability to respond to GIP. Indeed, exogenously delivered GIP induced proliferation of adult-derived hippocampal progenitors in vivo as well as in vitro, and adult GIP receptor knock-out mice exhibit a significantly lower number of newborn cells in the hippocampal DG compared with wild-type mice. This investigation demonstrates the presence of GIP in the brain for the first time and provides evidence for a regulatory function for GIP in progenitor cell proliferation.
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| 19. |
- Patten, Christopher, 1968-, et al.
(författare)
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Driver experience and cognitive workload in different traffic environments.
- 2006
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Ingår i: Accident Analysis and Prevention. - : Elsevier BV. - 0001-4575 .- 1879-2057. ; 38:5, s. 887-894
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Tidskriftsartikel (refereegranskat)abstract
- How do levels of cognitive workload differ between experienced and inexperienced drivers? In this study we explored cognitive workload and driver experience, using a secondary task method, the peripheral detection task (PDT) in a field study. The main results showed a large and statistically significant difference in cognitive workload levels between experienced and inexperienced drivers. Inexperienced, low mileage drivers had on average approximately 250 milliseconds (ms) longer reaction times to a peripheral stimulus, than the experienced drivers. It would, therefore, appear that drivers with better training and experience were able to automate the driving task more effectively than their less experienced counterparts in accordance with theoretical psychological models. It has been suggested that increased training and experience may provide attention resource savings that can benefit the driver in handling new or unexpected traffic situations.
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| 20. |
- von Koch, Christopher, et al.
(författare)
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Does shareholder protection affect the performance of analysts as a gatekeeper?
- 2014
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Ingår i: Journal of Management and Governance. - : Springer Science and Business Media LLC. - 1385-3457 .- 1572-963X. ; 18:2, s. 315-345
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Tidskriftsartikel (refereegranskat)abstract
- This paper investigates the effect of shareholder protection on analysts’ performance. The important corporate governance role analysts can play by monitoring management has largely been ignored in the literature. Using a newly constructed index, we are for the first time able to analyse how changes in shareholder protection over time affect analysts’ performance as a gatekeeper. We find that strengthened shareholder protection improves analysts’ performance as a gatekeeper, i.e. analysts’ ability to reduce information asymmetry improves with strengthened shareholder protection. However, we also find a substitution effect: Strengthened shareholder protection makes analysts’ services less valuable to investors, thereby leading to a reduction in the number of analysts following firms.
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| 21. |
- von Koch, Christopher, et al.
(författare)
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In search of corporate governance in franchising
- 2020
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Ingår i: Journal of Marketing Channels. - : Taylor & Francis. - 1046-669X .- 1540-7039. ; 26:3, s. 178-193
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Tidskriftsartikel (refereegranskat)abstract
- A firm's governance structure and business model might explain the firm’s failure or success. Franchising is a business model that has not received much attention within the corporate governance (CG) literature even though it obviously brings several unique CG challenges. Therefore, we review articles at the interface of CG and franchising. We identify and thematize the literature in four focus areas, each with a different relationship to CG: 1) traditional CG, 2) governance challenges unique to franchising, 3) governance modes, and 4) contracts. We find that the literature largely ignores the traditional view of CG when examining many aspects of franchising. We also find that the franchising literature covers governance topics when discussing governance modes, which provides a basis for developing CG theories. Altogether, our findings open a promising avenue for future research that incorporates CG into studies of franchising.
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