| 1. |
- Niemi, MEK, et al.
(author)
-
- 2021
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swepub:Mat__t
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| 2. |
- Kanai, M, et al.
(author)
-
- 2023
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swepub:Mat__t
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| 3. |
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| 4. |
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| 5. |
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| 6. |
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- 2019
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Journal article (peer-reviewed)
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| 7. |
- Kattge, Jens, et al.
(author)
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TRY plant trait database - enhanced coverage and open access
- 2020
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In: Global Change Biology. - : Wiley-Blackwell. - 1354-1013 .- 1365-2486. ; 26:1, s. 119-188
-
Journal article (peer-reviewed)abstract
- Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.
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| 8. |
- Tobias, Deirdre K, et al.
(author)
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Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine
- 2023
-
In: Nature Medicine. - 1546-170X. ; 29:10, s. 2438-2457
-
Research review (peer-reviewed)abstract
- Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations. Diabetes affects hundreds of millions of people worldwide, many of whom will develop life-threatening complications and die prematurely. Precision medicine can potentially address this enormous problem by accounting for heterogeneity in the etiology, clinical presentation and pathogenesis of common forms of diabetes and risks of complications. This second international consensus report on precision diabetes medicine summarizes the findings from a systematic evidence review across the key pillars of precision medicine (prevention, diagnosis, treatment, prognosis) in four recognized forms of diabetes (monogenic, gestational, type 1, type 2). These reviews address key questions about the translation of precision medicine research into practice. Although not complete, owing to the vast literature on this topic, they revealed opportunities for the immediate or near-term clinical implementation of precision diabetes medicine; furthermore, we expose important gaps in knowledge, focusing on the need to obtain new clinically relevant evidence. Gaps include the need for common standards for clinical readiness, including consideration of cost-effectiveness, health equity, predictive accuracy, liability and accessibility. Key milestones are outlined for the broad clinical implementation of precision diabetes medicine.
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| 9. |
- Riley, M A, et al.
(author)
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Beyond band termination in Er-157 and the search for wobbling excitations in strongly deformed Hf-174
- 2005
-
In: Journal of Physics G: Nuclear and Particle Physics. - : IOP Publishing. - 0954-3899 .- 1361-6471. ; 31:10, s. 1735-1740
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Journal article (peer-reviewed)abstract
- High-spin terminating bands in heavy nuclei were first identified in nuclei around Er-158(90). While examples of special terminating states have been identified in a number of erbium isotopes, almost nothing is known about the states lying beyond band termination. In the present work the high-spin structure of Er-157 has been studied using the Gammasphere spectrometer. The subject of triaxial superdeformation and 'wobbling' modes in Lu nuclei has rightly attracted a great deal of attention. Very recently, four strongly or superdeformed (SD) sequences have been observed in Hf-174 and ultimate cranker calculations predict, such structures may have significant triaxial deformation. We have performed two experiments in an attempt to verify the possible triaxial nature of these bands. A lifetime measurement was performed to confirm the large (and similar) deformation of the bands. In addition, a high-statistics, thin-target experiment was run to search for linking transitions between the SD bands and possible wobbling modes.
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| 10. |
- Riley, M. A., et al.
(author)
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Observation of states beyond band termination in Er-156,Er-157,Er-158 and strongly deformed structures in Hf-173,Hf-174,Hf-175
- 2006
-
In: Physica Scripta. - 0031-8949. ; T125, s. 123-126
-
Journal article (peer-reviewed)abstract
- High-spin terminating bands in heavy nuclei were first identified in nuclei around Er-158(90). While examples of terminating states have been identified in a number of erbium isotopes, almost nothing is known about the states lying beyond band termination. In the present work, the high-spin structure of Er-156,Er-157,Er-158 has been studied using the Gammasphere spectrometer. The subject of triaxial superdeformation and 'wobbling' modes in Lu nuclei has rightly attracted a great deal of attention. Very recently four strongly or superdeformed (SD) sequences have been observed in Hf-174, and cranking calculations using the Ultimate Cranker code predict that such structures may have significant triaxial deformation. We have performed two experiments in an attempt to verify the possible triaxial nature of these bands. A lifetime measurement was performed to confirm the large (and similar) deformation of the bands. In addition, a high-statistics, thin-target experiment took place to search for linking transitions between the SD bands, possible wobbling modes, and new SD band structures.
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| 11. |
- Schweinsberg, Martin, et al.
(author)
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Same data, different conclusions : Radical dispersion in empirical results when independent analysts operationalize and test the same hypothesis
- 2021
-
In: Organizational Behavior and Human Decision Processes. - : Elsevier BV. - 0749-5978 .- 1095-9920. ; 165, s. 228-249
-
Journal article (peer-reviewed)abstract
- In this crowdsourced initiative, independent analysts used the same dataset to test two hypotheses regarding the effects of scientists' gender and professional status on verbosity during group meetings. Not only the analytic approach but also the operationalizations of key variables were left unconstrained and up to individual analysts. For instance, analysts could choose to operationalize status as job title, institutional ranking, citation counts, or some combination. To maximize transparency regarding the process by which analytic choices are made, the analysts used a platform we developed called DataExplained to justify both preferred and rejected analytic paths in real time. Analyses lacking sufficient detail, reproducible code, or with statistical errors were excluded, resulting in 29 analyses in the final sample. Researchers reported radically different analyses and dispersed empirical outcomes, in a number of cases obtaining significant effects in opposite directions for the same research question. A Boba multiverse analysis demonstrates that decisions about how to operationalize variables explain variability in outcomes above and beyond statistical choices (e.g., covariates). Subjective researcher decisions play a critical role in driving the reported empirical results, underscoring the need for open data, systematic robustness checks, and transparency regarding both analytic paths taken and not taken. Implications for orga-nizations and leaders, whose decision making relies in part on scientific findings, consulting reports, and internal analyses by data scientists, are discussed.
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| 12. |
- Carleo, Ilaria, et al.
(author)
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The Multiplanet System TOI-421*
- 2020
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In: Astronomical Journal. - : American Astronomical Society. - 1538-3881 .- 0004-6256. ; 160:3
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Journal article (peer-reviewed)abstract
- We report the discovery of a warm Neptune and a hot sub-Neptune transiting TOI-421 (BD-14 1137, TIC 94986319), a bright (V = 9.9) G9 dwarf star in a visual binary system observed by the Transiting Exoplanet Survey Satellite (TESS) space mission in Sectors 5 and 6. We performed ground-based follow-up observations-comprised of Las Cumbres Observatory Global Telescope transit photometry, NIRC2 adaptive optics imaging, and FIbre-fed Echelle Spectrograph, CORALIE, High Accuracy Radial velocity Planet Searcher, High Resolution echelle Spectrometer, and Planet Finder Spectrograph high-precision Doppler measurements-and confirmed the planetary nature of the 16 day transiting candidate announced by the TESS team. We discovered an additional radial velocity signal with a period of five days induced by the presence of a second planet in the system, which we also found to transit its host star. We found that the inner mini-Neptune, TOI-421 b, has an orbital period of P-b = 5.19672 +/- 0.00049 days, a mass of M-b = 7.17 +/- 0.66 M-circle plus, and a radius of R-b = R-circle plus, whereas the outer warm Neptune, TOI-421 c, has a period of P-c = 16.06819 +/- 0.00035 days, a mass of M-c = 16.42(-1.04)(+1.06)M(circle plus), a radius of R-c = 5.09(-0.15)(+0.16)R(circle plus), and a density of rho(c) = 0.685(-0.072)(+0.080) cm(-3). With its characteristics, the outer planet (rho(c) = 0.685(-0.0072)(+0.080) cm(-3)) is placed in the intriguing class of the super-puffy mini-Neptunes. TOI-421 b and TOI-421 c are found to be well-suited for atmospheric characterization. Our atmospheric simulations predict significant Ly alpha transit absorption, due to strong hydrogen escape in both planets, as well as the presence of detectable CH4 in the atmosphere of TOI-421 c if equilibrium chemistry is assumed.
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| 13. |
- Mustafa, M., et al.
(author)
-
Diverse collective excitations in Er-159 up to high spin
- 2011
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 84:5
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Journal article (peer-reviewed)abstract
- A spectroscopic investigation of the gamma decays from excited states in Er-159 has been performed to study the changing structural properties exhibited as ultrahigh spins (I > 60 (h) over bar) are approached. The nucleus of Er-159 was populated by the reaction Cd-116(Ca-48, 5n gamma) at a beam energy of 215 MeV, and the resulting gamma decays were studied using the Gammasphere spectrometer. New rotational bands and extensions to existing sequences were observed, which are discussed in terms of the cranked shell model, revealing a diverse range of quasiparticle configurations. At spins around 50 (h) over bar, there is evidence for a change from dominant prolate collective motion at the yrast line to oblate non-collective structures via the mechanism of band termination. A possible strongly deformed triaxial band occurs at these high spins, which indicates collectivity beyond 50 (h) over bar. The high-spin data are interpreted within the framework of cranked Nilsson-Strutinsky calculations.
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| 14. |
- Riley, M. A., et al.
(author)
-
Strongly Deformed Nuclear Shapes at Ultra-High Spin and Shape Coexistence in N\sim 90 Nuclei
- 2009
-
In: Acta Physica Polonica B. - 0587-4254. ; 40:3, s. 513-522
-
Journal article (peer-reviewed)abstract
- The N similar to 90 region of the nuclear chart has featured prominently as the spectroscopy of nuclei at extreme spin has progressed. This talk will present recent discoveries from investigations of high spin behavior in the N similar to 90 Er, Tm and Yb nuclei utilizing the Gammasphere gamma-ray spectrometer. In particular it will include discussion of the beautiful shape evolution and coexistence observed in these nuclei along with the identification of a remarkable new family of band structures. The latter are very weakly populated rotational sequences with high moment of inertia that bypass the classic terminating configurations near spin 40-50 (h) over bar, marking a return to collectivity that extends discrete gamma-ray spectroscopy to well over 60 (h) over bar. Establishing the nature of the yrast states in these nuclei beyond the oblate band-termination states has been a major goal for the past two decades. Cranking calculations suggest that these new structures most likely represent stable triaxial strongly deformed bands that lie in a valley of favored shell energy in deformation and particle-number space.
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| 15. |
- Simpson, J., et al.
(author)
-
Evolution of structure and shapes in Er 158 to ultrahigh spin
- 2023
-
In: Physical Review C. - 2469-9985. ; 107:5
-
Journal article (peer-reviewed)abstract
- The level structure of Er158 has been studied using the Gammasphere spectrometer via the Cd114(Ca48,4n) reaction at 215 MeV with both thin (self-supporting) and thick (backed) targets. The level scheme has been considerably extended with more than 200 new transitions and six new rotational structures, including two strongly coupled high-K bands. Configuration assignments for the new structures are based on their observed alignments, B(M1)/B(E2) ratios of reduced transition probabilities, excitation energies, and comparisons with neighboring nuclei and theoretical calculations. With increasing angular momentum, this nucleus exhibits Coriolis-induced alignments of both neutrons and protons before it then undergoes a rotation-induced transition from near-prolate collective rotation to a noncollective oblate configuration. This transition occurs via the mechanism of band termination around spin 45ħ in three rotational structures. Two distinct lifetime branches, consistent with the crossing of a collective "fast"rotational structure by an energetically favored "slow"terminating sequence, are confirmed for the positive-parity states, and similar behavior is established in the negative-parity states. Weak-intensity, high-energy transitions are observed to feed into the terminating states. At the highest spins, three collective bands with high dynamic moments of inertia and large quadrupole moments were identified. These bands are interpreted as triaxial strongly deformed structures and mark a return to collectivity at ultrahigh spin.
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| 16. |
- Wang, X., et al.
(author)
-
Collective structures up to spin ∼ 65h in the N 90 isotones 158Er and 157Ho
- 2012
-
In: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 381:1
-
Journal article (peer-reviewed)abstract
- A new collective band with high dynamic moment of inertia in 158Er at spins beyond band termination has been found in addition to the two previously reported ones. The measured transition quadrupole moments (Qt) of these three bands are very similar. These three bands have been suggested to possess a triaxial strongly deformed shape, based on comparisons with calculations using the cranked Nilsson-Strutinsky model and with tilted axis cranking calculations using the Skyrme-Hartree-Fock model. In addition, three collective bands with similar high dynamic moments of inertia, tentatively assigned to 157Ho, have been observed. Thus, it is suggested that all these structures share a common underlying character and that they are most likely associated with triaxial strongly deformed minima which are predicted to be close to the yrast line at spin 50 - 70h.
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| 17. |
- Hartley, D. J., et al.
(author)
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Persistence of collective behavior at high spin in the N=88 nucleus Tb-153
- 2015
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 91:5
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Journal article (peer-reviewed)abstract
- Excited states in the N = 88 nucleus Tb-153 were observed up to spin similar to 40 in an experiment utilizing the Gammasphere array. The Tb-153 states were populated in a weak alpha 4n evaporation channel of the Cl-37 + Sn-124 reaction. Two previously known sequences were extended to higher spins, and a new decoupled structure was identified. The pi h(11/2) band was observed in the spin region where other N = 88 isotopes exhibit effects of prolate to oblate shape changes leading to band termination along the yrast line, whereas Tb-153 displays a persistent collective behavior. However, minor perturbations of the very highest state in both signatures of this h(11/2) band are observed, which perhaps signal the start of the transition towards band termination.
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| 18. |
- Joss, D T, et al.
(author)
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Lifetime measurements of a triaxial band in Ce-133
- 1998
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In: Acta Physica Hungarica A. - 1219-7580 .- 1588-2675. ; 7:1, s. 111-112
-
Journal article (peer-reviewed)abstract
- The Doppler shift attenuation method has been used to determine the transition quadrupole moment of a triaxial band belonging to the gamma-soft nucleus, Ce-133. Doppler broadened lineshape (DBLS) analysis has revealed the magnitude of the Q(t) value to be similar to 2.4 eb. This contribution provides new information of (i) the transition quadrupole moment of this band (ii) the lifetimes of in-band and sidefeeding transitions and (iii) the relative deformations of coexisting nuclear shapes.
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| 19. |
- Joss, D T, et al.
(author)
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Lifetime measurements of a triaxial band in Ce-133
- 1998
-
In: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 58:6, s. 3219-3222
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Journal article (peer-reviewed)abstract
- Lifetimes of states within a triaxial band belonging to;the gamma-soft nucleus Ce-133 have been determined through a Doppler-broadened line shape analysis. A value, Q(t)approximate to 2.2 eb, has been found for the transition quadrupole moment which is considerably smaller than that of superdeformed structures (Q(t)approximate to 7.4 e b) in this mass region. The results are discussed in terms of deformation self-consistent calculations based on the total Routhian surface formalism. [S0556-2813(98)01912-8].
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| 20. |
- Kilpeläinen, Tuomas O, et al.
(author)
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Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.
- 2011
-
In: PLoS medicine. - : Public Library of Science (PLoS). - 1549-1676 .- 1549-1277. ; 8:11
-
Journal article (peer-reviewed)abstract
- BACKGROUND: The FTO gene harbors the strongest known susceptibility locus for obesity. While many individual studies have suggested that physical activity (PA) may attenuate the effect of FTO on obesity risk, other studies have not been able to confirm this interaction. To confirm or refute unambiguously whether PA attenuates the association of FTO with obesity risk, we meta-analyzed data from 45 studies of adults (n=218,166) and nine studies of children and adolescents (n=19,268). METHODS AND FINDINGS: All studies identified to have data on the FTO rs9939609 variant (or any proxy [r(2)>0.8]) and PA were invited to participate, regardless of ethnicity or age of the participants. PA was standardized by categorizing it into a dichotomous variable (physically inactive versus active) in each study. Overall, 25% of adults and 13% of children were categorized as inactive. Interaction analyses were performed within each study by including the FTO×PA interaction term in an additive model, adjusting for age and sex. Subsequently, random effects meta-analysis was used to pool the interaction terms. In adults, the minor (A-) allele of rs9939609 increased the odds of obesity by 1.23-fold/allele (95% CI 1.20-1.26), but PA attenuated this effect (p(interaction) =0.001). More specifically, the minor allele of rs9939609 increased the odds of obesity less in the physically active group (odds ratio =1.22/allele, 95% CI 1.19-1.25) than in the inactive group (odds ratio =1.30/allele, 95% CI 1.24-1.36). No such interaction was found in children and adolescents. CONCLUSIONS: The association of the FTO risk allele with the odds of obesity is attenuated by 27% in physically active adults, highlighting the importance of PA in particular in those genetically predisposed to obesity.
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| 21. |
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| 22. |
- Ollier, J., et al.
(author)
-
Structure changes in Er-160 from low to ultrahigh spin
- 2011
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 83:4
-
Journal article (peer-reviewed)abstract
- A spectroscopic investigation of the gamma decays from excited states in Er-160 has been performed in order to study the changing structural properties exhibited from low spin up toward ultrahigh spin (I similar to 60 h). The nucleus Er-160 was populated by the reaction Cd-116(Ca-48,4n gamma) at a beam energy of 215 MeV, and resulting gamma decays were studied using the Gammasphere spectrometer. New rotational structures and extensions to existing bands were observed, revealing a diverse range of quasiparticle configurations, which are discussed in terms of the cranked shell model. At spins around 50h there is evidence for oblate states close to the yrast line. Three rotational bands that have the characteristics of strongly deformed triaxial structures are observed, marking a return to collectivity at even higher spin. The high-spin data are interpreted within the framework of cranked Nilsson-Strutinsky calculations.
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| 23. |
- Paul, E. S., et al.
(author)
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Recent Results at Ultrahigh Spin: Terminating States and Beyond in Mass 160 Rare-earth Nuclei
- 2015
-
In: Acta Physica Polonica. Series B: Elementary Particle Physics, Nuclear Physics, Statistical Physics, Theory of Relativity, Field Theory. - 0587-4254. ; 46:3, s. 487-496
-
Journal article (peer-reviewed)abstract
- A classic region of band termination at high spin occurs in rare-earth nuclei with around ten valence nucleons above the Gd-146 closed core. Results are presented here for such non-collective oblate (gamma = 60 degrees) terminating states in odd-Z Ho-155, odd-odd Ho-156, and even-even Er-156, where they are compared with neighbouring nuclei. In addition to these particularly favoured states, the occurrence of collective triaxial strongly deformed (TSD) bands, bypassing the terminating states and extending to over 65 (h) over bar, is reviewed.
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| 24. |
- Pfohl, J., et al.
(author)
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Highly deformed rotational structures in 136Pm
- 2000
-
In: Physical Review C - Nuclear Physics. - 0556-2813. ; 62:3, s. 313041-313045
-
Journal article (peer-reviewed)abstract
- Four highly deformed structures in the odd-odd nucleus 13661Pm75 were observed via the 105Pd(35Cl,2p2n) reaction at 180 and 173 MeV using the GAMMASPHERE γ-ray spectrometer and the Microball charged-particle detector array. Quadrupole moment measurements were performed on all of the bands. In contrast to lighter odd-Ζ Pm and Pr nuclei, bands based on the g9/2[404]9/2 proton orbital were not observed. Instead, the four observed sequences are assigned as a coupling of an i13/2 neutron with the low-Ω h11/2 and mixed d5/2g7/2 orbitals. Comparisons with neighboring highly deformed structures are discussed and cranked Nilsson-Strutinsky calculations for 136Pm are presented.
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| 25. |
- Rees, J. M., et al.
(author)
-
High-spin terminating states in the N=88 Ho-155 and Er-156 isotones
- 2015
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 91:5
-
Journal article (peer-reviewed)abstract
- The Sn-124(Cl-37, 6n gamma) fusion-evaporation reaction at a bombarding energy of 180 MeV has been used to significantly extend the excitation level scheme of Ho-155(67)88. The collective rotational behavior of this nucleus breaks down above spin I similar to 30 and a fully aligned noncollective (band terminating) state has been identified at I-pi = 79/2(-). Comparison with cranked Nilsson-Strutinsky calculations also provides evidence for core-excited noncollective states at I-pi = 87/2(-) and (89/2(+)) involving particle-hole excitations across the Z = 64 shell gap. A similar core-excited state in Er-156(68)88 at I-pi = (46(+)) is also presented.
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| 26. |
- Wang, X., et al.
(author)
-
Quadrupole moments of collective structures up to spin similar to 65(h)over-bar in Er-157 and Er-158: A challenge for understanding triaxiality in nuclei
- 2011
-
In: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 702:2-3, s. 127-130
-
Journal article (peer-reviewed)abstract
- The transition quadrupole moments. Q(t), of four weakly populated collective bands up to spin similar to 65h in Er-157,Er-158 have been measured to be similar to II eb demonstrating that these sequences are associated with large deformations. However, the data are inconsistent with calculated values from cranked Nilsson-Strutinsky calculations that predict the lowest energy triaxial shape to be associated with rotation about the short principal axis. The data appear to favor either a stable triaxial shape rotating about the intermediate axis or, alternatively, a triaxial shape with larger deformation rotating about the short axis. These new results challenge the present understanding of triaxiality in nuclei. (C) 2011 Elsevier B.V. All rights reserved.
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| 27. |
- Atac, A, et al.
(author)
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Single-step link of the superdeformed band in Eu-143
- 1996
-
In: ZEITSCHRIFT FUR PHYSIK A-HADRONS AND NUCLEI. - : SPRINGER VERLAG. - 0939-7922. ; 355:4, s. 343-344
-
Journal article (other academic/artistic)abstract
- A discrete gamma-ray transition with an energy of 3360.6 keV deexciting the second lowest SD state in Eu-143 has been discovered. It carries 3.2 % of the full intensity of the band and feeds into a nearly spherical state which is above the I = 35/2((+)),
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| 28. |
- Axelsson, A, et al.
(author)
-
Single-step link from yrast SD band in Eu-143
- 1997
-
In: PROGRESS IN PARTICLE AND NUCLEAR PHYSICS. - : PERGAMON PRESS LTD. - 0146-6410. ; 38, s. 51-52
-
Journal article (other academic/artistic)abstract
- A discrete gamma-ray transition from the yrast SD band to the region of near-yrast discrete normal-deformed states has been identified in Eu-143. It has an energy of 3360.6 keV and an intensity corresponding to 3.2% of the full intensity of the SD band an
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| 29. |
- Evans, A. O., et al.
(author)
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Magnetic properties of deformed dipole bands in Te-110,Te-112
- 2006
-
In: Physica Scripta. - 0031-8949. ; T125, s. 192-193
-
Journal article (peer-reviewed)abstract
- A lifetime analysis using the Doppler-shift attenuation method has been performed on the Tellurium isotopes Te-110,Te-112. The experiment was performed using the Gammasphere array in conjunction with the MICROBALL charged-particle detector. Three strongly coupled bands were previously established in Te-110,Te-112 which were observed up to unusually high spins. In the current experiment, it has been possible to extract lifetime measurements using a Doppler broadened lineshape analysis on one of the Delta I = 1 band structures in Te-110. In contrast to similar Delta I = 1 structures in other nuclei in this mass region, the extracted B(M1) values did not rapidly decrease with increasing angular momentum. Instead, the strongly coupled band in Te-110 represents a deformed 1p-1h structure, rather than a weakly deformed structure showing the shears mechanism.
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| 30. |
- Ji, Andrew L., et al.
(author)
-
Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma
- 2020
-
In: Cell. - : Cell Press. - 0092-8674 .- 1097-4172. ; 182:2, s. 497-
-
Journal article (peer-reviewed)abstract
- To define the cellular composition and architecture of cutaneous squamous cell carcinoma (cSCC), we combined single-cell RNA sequencing with spatial transcriptomics and multiplexed ion beam imaging from a series of human cSCCs and matched normal skin. cSCC exhibited four tumor subpopulations, three recapitulating normal epidermal states, and a tumor-specific keratinocyte (TSK) population unique to cancer, which localized to a fibrovascular niche. Integration of single-cell and spatial data mapped ligand-receptor networks to specific cell types, revealing TSK cells as a hub for intercellular communication. Multiple features of potential immunosuppression were observed, including T regulatory cell (Treg) co-localization with CD8 T cells in compartmentalized tumor stroma. Finally, single-cell characterization of human tumor xenografts and in vivo CRISPR screens identified essential roles for specific tumor subpopulation-enriched gene networks in tumorigenesis. These data define cSCC tumor and stromal cell subpopulations, the spatial niches where they interact, and the communicating gene networks that they engage in cancer.
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| 31. |
- Leoni, S, et al.
(author)
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Four independent decay properties in the super-deformed well of Eu-143
- 1997
-
In: PHYSICS LETTERS B. - : ELSEVIER SCIENCE BV. - 0370-2693. ; 409:1-4, s. 71-76
-
Journal article (other academic/artistic)abstract
- The flow of gamma-transitions through the superdeformed minimum of Eu-143 is investigated by studying the intensities of four different types of gamma-rays of superdeformed origin, obtained with a variety of gating conditions. They can all be explained ra
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| 32. |
- Ollier, J., et al.
(author)
-
Ultrahigh-spin spectroscopy of Er-159,Er-160: Observation of triaxial strongly deformed structures
- 2009
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 80:6
-
Journal article (peer-reviewed)abstract
- Three weakly populated high-spin rotational bands associated with the gamma decay of Er-159 and Er-160 were observed in fusion-evaporation reactions involving a beam of Ca-48 at an energy of 215 MeV incident on a Cd-116 target. The gamma decays were detected using the highly efficient Gammasphere spectrometer. The discovery of these bands, which extend discrete-line spectroscopy in these nuclei to ultrahigh spin of similar to 60h, is consistent with recent observations of high-spin collective structures in isotopes of Er, Yb, and Tm around N=90. Cranked Nilsson-Strutinsky calculations suggest that these bands may arise from well-deformed triaxial configurations with either positive or negative gamma deformation.
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| 33. |
- Paul, E. S., et al.
(author)
-
High-spin yrast states in the gamma-soft nuclei Pr-135 and Ce-134
- 2011
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 84:4
-
Journal article (peer-reviewed)abstract
- High-spin states have been studied in Pr-135(59), populated through the Cd-116(Na-23,4n) reaction at 115 MeV, using the Gammasphere gamma-ray spectrometer. The negative-parity yrast band has been significantly extended to spin similar to 45 (h) over bar and excitation energy 21.5 MeV, showing evidence for several rotational alignments. The positive-parity yrast band of Ce-135(58), populated through the p4n channel of this reaction, was also populated to spin similar to 38 (h) over bar and excitation energy 18 MeV. Cranking calculations indicate that these nuclei are soft with respect to the triaxiality parameter gamma and that several competing nuclear shapes occur at high spin.
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| 34. |
- Paul, E. S., et al.
(author)
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Loss of collectivity in the transitional Er-156 nucleus at high spin
- 2009
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 79:4
-
Journal article (peer-reviewed)abstract
- The Cd-114(Ca-48, 6n gamma) reaction at 215 MeV has been investigated using the Gammasphere spectrometer to study the high-spin structure of the nucleus Er-156(68)88. Many new transitions have been established along with 68 definitive spin-parity level assignments from a high-fold angular-distribution analysis. In addition, absolute B(M 1) and B(E 1) strengths have been inferred from measured gamma-ray branching ratios. Strong B(E 1) strength (10(-3) W.u.) is discussed in terms of possible octupole collectivity at low spin. At high spin, this nucleus undergoes a Coriolis-induced shape transition from a prolate state of collective rotation to a noncollective, triaxial-oblate configuration. The yrast positive-parity structure ultimately terminates in an energetically favored oblate state at I-pi = 42(+). Several weak high-energy gamma-ray transitions have been discovered that feed this favored state. State-of-the-art cranked Nilsson-Strutinsky calculations are used to interpret the high-spin behavior of Er-156 and comparisons are made with other N = 88 isotones.
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| 35. |
- Paul, E. S., et al.
(author)
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Return of collective rotation in Er-157 and Er-158 at ultrahigh spin
- 2007
-
In: Physical Review Letters. - 1079-7114. ; 98:1, s. 1-012501
-
Journal article (peer-reviewed)abstract
- A new frontier of discrete-line gamma-ray spectroscopy at ultrahigh spin has been opened in the rare-earth nuclei Er-157,Er-158. Four rotational structures, displaying high moments of inertia, have been identified, which extend up to spin similar to 65h and bypass the band-terminating states in these nuclei which occur at similar to 45h. Cranked Nilsson-Strutinsky calculations suggest that these structures arise from well-deformed triaxial configurations that lie in a valley of favored shell energy which also includes the triaxial strongly deformed bands in Lu161-167.
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| 36. |
- Paul, E. S., et al.
(author)
-
Smooth terminating bands in Te-112: Particle-hole induced collectivity
- 2007
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 75:1
-
Journal article (peer-reviewed)abstract
- The Gammasphere spectrometer, in conjunction with the Microball charged-particle array, was used to investigate high-spin states in Te-112 via Ni-58(Ni-58, 4p gamma) reactions at 240 and 250 MeV. Several smooth terminating bands were established, and lifetime measurements were performed for the strongest one using the Doppler-shift attenuation method. Results obtained in the spin range 18-32h yield a transition quadrupole moment of 4.0 +/- 0.5eb, which corresponds to a quadrupole deformation epsilon(2)=0.26 +/- 0.03; this value is significantly larger than the ground-state deformation of tellurium isotopes. It was also possible to extract a transition quadrupole moment for the yrast band in Xe-114, produced via the 58Ni (58Ni, 2p gamma) reaction. A value of 3.0 +/- 0.5eb was found in the spin range 16-24h, which corresponds to a quadrupole deformation epsilon(2)=0.19 +/- 0.03. Cranked Nilsson-Strutinsky calculations are used to interpret the results.
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| 37. |
- Revill, J. P., et al.
(author)
-
Quadrupole moments of coexisting collective shapes at high spin in Er-154
- 2013
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 88:3
-
Journal article (peer-reviewed)abstract
- Four high-spin collective bands have been populated in Er-154(68)86 via the Pd-110(Ti-48, (4)n gamma)Er-154 reaction. Average transition quadrupole moments Q(t) have been measured for three of the bands by using the Doppler-shift attenuation method. The strongest band has a value of Q(t) = 11.0 +/- 1.0 e b, similar to values found recently for four triaxial strongly deformed (TSD) bands in Er-157,Er-158. The second band has a value of Q(t) = 19.5 +/- 3.2 e b, consistent with a predicted axially symmetric superdeformed (SD) shape, similar in deformation to the Dy-152 isotone, and is used as a calibration point. The third, new band has a value of Q(t) = 9.9 +/- 2.2 e b. The results confirm the unexpectedly large Q(t) moments for the favored TSD bands in light erbium isotopes.
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| 38. |
- Revill, J. P., et al.
(author)
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Relative quadrupole moments of exotic shapes at ultrahigh spin in 154Er : Calibrating the TSD/SD puzzle
- 2012
-
In: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596.
-
Conference paper (peer-reviewed)abstract
- Transition quadrupole moments, Qt, of two ultrahigh-spin, collective structures in 154Er have been measured for the first time using the Doppler Shift Attenuation Method (DSAM). Data were acquired at the ATLAS accelerator facility of Argonne National Laboratory, using the Gammasphere detector array. A thick, gold-backed 110Pd foil was bombarded by a beam of 48Ti ions at 215 MeV. The Qt for each band was determined from the Doppler shift of gamma rays emitted by the resulting recoil nuclei. The extracted transition quadrupole moments are significantly different in magnitude, suggesting the two structures in 154Er represent distinct exotic nuclear shapes, namely axial superdeformed (SD) with Q t 20 eb, and triaxial strongly deformed (TSD) with Qt ≈ 11 eb. Indeed, the results calibrate the quadrupole moments of TSD bands recently measured in light erbium nuclei, 157,158Er.
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| 39. |
- Döscher, Ralf, et al.
(author)
-
The EC-Earth3 Earth system model for the Coupled Model Intercomparison Project 6
- 2022
-
In: Geoscientific Model Development. - : Copernicus GmbH. - 1991-959X .- 1991-9603. ; 15:7, s. 2973-3020
-
Journal article (peer-reviewed)abstract
- The Earth system model EC-Earth3 for contributions to CMIP6 is documented here, with its flexible coupling framework, major model configurations, a methodology for ensuring the simulations are comparable across different high-performance computing (HPC) systems, and with the physical performance of base configurations over the historical period. The variety of possible configurations and sub-models reflects the broad interests in the EC-Earth community. EC-Earth3 key performance metrics demonstrate physical behavior and biases well within the frame known from recent CMIP models. With improved physical and dynamic features, new Earth system model (ESM) components, community tools, and largely improved physical performance compared to the CMIP5 version, EC-Earth3 represents a clear step forward for the only European community ESM. We demonstrate here that EC-Earth3 is suited for a range of tasks in CMIP6 and beyond.
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| 40. |
- Paul, E. S., et al.
(author)
-
The highest spin discrete levels in Ce-131,Ce-132
- 2006
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In: Physica Scripta. - 0031-8949. ; T125, s. 115-118
-
Journal article (peer-reviewed)abstract
- The three superdeformed (SD) bands in Ce-132 and the two SD bands in Ce-131 have been extended to higher spin following experiments with the EUROBALL IV spectrometer. The two SD bands in 131Ce have been linked together. However, despite the relatively high population intensity of the bands ( up to 5% of the respective channel), it has not been possible to unambiguously link any of the five SD bands into the low-spin, normally deformed structures of Ce-131,Ce-132.
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| 41. |
- Starosta, K., et al.
(author)
-
Smooth band termination at high spin in 113I
- 2001
-
In: Physical Review C - Nuclear Physics. - 0556-2813. ; 64:1, s. 143041-1430419
-
Journal article (peer-reviewed)abstract
- The 113I nucleus has been studied using the 58Ni(58Ni,3p) reaction at 250 MeV with the Gammasphere/ Microball facility. Gamma-ray three-and four-fold data gated by charged particle combinations were analyzed. Multipolarities of the γ rays were assigned following the angular correlation measurements. The present study is focused on the high spin properties, where the structure is dominated by 2p-2h excitations across the Z=50 gap. Ten decoupled bands showing the features of smooth band termination were observed; three of those bands are linked to known low-spin states, which allows the identification of configurations by direct comparisons with configuration-dependent cranked Nilsson-Strutinsky calculations. The yrast band, which was linked along with the signature partner, was followed up to (101/2+) and ℏω∼1.3 MeV. The other linked band was a negative-parity band observed up to (95/2-). Tentative configurations for the unlinked bands are discussed. Comparisons with the theoretical results suggest that the band built on a configuration involving the neutron i13/2 intruder orbital originating from the N=6 harmonic oscillator subshell was observed in this experiment.
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| 42. |
- Chung, Wendy K., et al.
(author)
-
Precision medicine in diabetes : a Consensus Report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
- 2020
-
In: Diabetologia. - : Springer Science and Business Media LLC. - 0012-186X .- 1432-0428. ; 63:9, s. 1671-1693
-
Journal article (peer-reviewed)abstract
- The convergence of advances in medical science, human biology, data science and technology has enabled the generation of new insights into the phenotype known as ‘diabetes’. Increased knowledge of this condition has emerged from populations around the world, illuminating the differences in how diabetes presents, its variable prevalence and how best practice in treatment varies between populations. In parallel, focus has been placed on the development of tools for the application of precision medicine to numerous conditions. This Consensus Report presents the American Diabetes Association (ADA) Precision Medicine in Diabetes Initiative in partnership with the European Association for the Study of Diabetes (EASD), including its mission, the current state of the field and prospects for the future. Expert opinions are presented on areas of precision diagnostics and precision therapeutics (including prevention and treatment) and key barriers to and opportunities for implementation of precision diabetes medicine, with better care and outcomes around the globe, are highlighted. Cases where precision diagnosis is already feasible and effective (i.e. monogenic forms of diabetes) are presented, while the major hurdles to the global implementation of precision diagnosis of complex forms of diabetes are discussed. The situation is similar for precision therapeutics, in which the appropriate therapy will often change over time owing to the manner in which diabetes evolves within individual patients. This Consensus Report describes a foundation for precision diabetes medicine, while highlighting what remains to be done to realise its potential. This, combined with a subsequent, detailed evidence-based review (due 2022), will provide a roadmap for precision medicine in diabetes that helps improve the quality of life for all those with diabetes.
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| 43. |
- Chung, Wendy K., et al.
(author)
-
Precision Medicine in Diabetes : A Consensus Report From the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
- 2020
-
In: Diabetes Care. - : American Diabetes Association. - 1935-5548 .- 0149-5992. ; 43:7, s. 1617-1635
-
Research review (peer-reviewed)abstract
- The convergence of advances in medical science, human biology, data science, and technology has enabled the generation of new insights into the phenotype known as "diabetes." Increased knowledge of this condition has emerged from populations around the world, illuminating the differences in how diabetes presents, its variable prevalence, and how best practice in treatment varies between populations. In parallel, focus has been placed on the development of tools for the application of precision medicine to numerous conditions. This Consensus Report presents the American Diabetes Association (ADA) Precision Medicine in Diabetes Initiative in partnership with the European Association for the Study of Diabetes (EASD), including its mission, the current state of the field, and prospects for the future. Expert opinions are presented on areas of precision diagnostics and precision therapeutics (including prevention and treatment), and key barriers to and opportunities for implementation of precision diabetes medicine, with better care and outcomes around the globe, are highlighted. Cases where precision diagnosis is already feasible and effective (i.e., monogenic forms of diabetes) are presented, while the major hurdles to the global implementation of precision diagnosis of complex forms of diabetes are discussed. The situation is similar for precision therapeutics, in which the appropriate therapy will often change over time owing to the manner in which diabetes evolves within individual patients. This Consensus Report describes a foundation for precision diabetes medicine, while highlighting what remains to be done to realize its potential. This, combined with a subsequent, detailed evidence-based review (due 2022), will provide a roadmap for precision medicine in diabetes that helps improve the quality of life for all those with diabetes.
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| 44. |
- Evans, AO, et al.
(author)
-
High-spin structure beyond band termination in Er-157
- 2004
-
In: Physical Review Letters. - 1079-7114. ; 92:25
-
Journal article (peer-reviewed)abstract
- The angular-momentum induced transition from a deformed state of collective rotation to a noncollective configuration has been studied. In Er-157 this transition manifests itself as favored band termination near I=45 (h) over bar. The feeding of these band terminating states has been investigated for the first time using the Gammasphere spectrometer. Many weakly populated states lying at high excitation energy that decay into these special states have been discovered. Cranked Nilsson-Strutinsky calculations suggest that these states arise from weakly collective "core-breaking" configurations.
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| 45. |
- Evans, AO, et al.
(author)
-
High-spin structure in Er-157 up to and above band termination
- 2006
-
In: Physical Review C (Nuclear Physics). - 0556-2813. ; 73:6
-
Journal article (peer-reviewed)abstract
- The high-spin structure of Er-157 has been greatly expanded using the Gammasphere spectrometer to investigate the Cd-114(Ca-48,5n) reaction at 215 MeV. Many new transitions have been placed in a greatly augmented level scheme up to spin 40h with many collective rotational sequences established. With increasing angular momentum, this nucleus undergoes a Coriolis-induced shape transition from a deformed state of collective rotation to a noncollective configuration. This transition manifests itself as favored band termination near I=45h in three rotational structures. Many weakly populated states lying at high excitation energy that decay into the terminating states have been discovered. Cranked-Nilsson-Strutinsky calculations suggest that the levels that feed the terminating states arise from weakly collective configurations that break the Z=64 semimagic core.
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| 46. |
- Evans, AO, et al.
(author)
-
Magnetic properties of smooth terminating dipole bands in Te-110,Te-112
- 2006
-
In: Physics Letters. Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 636:1, s. 25-30
-
Journal article (peer-reviewed)abstract
- Three strongly coupled sequences have been established in Te-110,Te-112 up to high spins. They are interpreted in terms of deformed structures built on proton 1-particle-1-hole excitations that reach termination at I similar to 40h. This is the first observation of smooth terminating dipole structures in this mass region. Lifetime measurements have allowed the extraction of experimental B(M 1; 1 -> I - 1) and B(E2; I -> I - 2) reduced transition rates for one of the dipole bands in Te-110. The results support the deformed interpretation. (c) 2006 Elsevier B.V. All rights reserved.
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| 47. |
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| 48. |
- Parry, C. M., et al.
(author)
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First evidence for smooth band termination in valence space in the mass 130 region : Spectroscopy of 127La
- 2000
-
In: Physical Review C - Nuclear Physics. - 0556-2813. ; 61:2, s. 213031-213035
-
Journal article (peer-reviewed)abstract
- High spin states in 127La have been studied using the 32S(100Mo,p4n) reaction at a beam energy of 155 MeV. Gamma rays were detected using the EUROBALL III spectrometer. One of the side bands in 127La is observed to be populated to a spin of 83/2+. These data are compared with cranked Nilsson-Strutinski calculations which suggest that the structure is a smoothly terminating band, in valence space, based upon a π[(g7/2d5/2)5(h11/2)2]⊗ ν[(g7/2d5/2)12(h11/2)6(d3/2s1/2)2] configuration, which can carry a maximum spin of 47.5ℏ. This is the first identification of such a structure in this mass region.
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