| 1. |
- Allard, Christina, et al.
(författare)
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Rasbiologiskt språkbruk i statens rättsprocess mot sameby
- 2015
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Ingår i: Dagens Nyheter. - 1101-2447.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Statens hantering av forskningsresultat i rättsprocessen med Girjas sameby utgör ett hot mot Sverige som rättsstat och kunskapsnation. Åratal av svensk och internationell forskning underkänns och man använder ett språkbruk som skulle kunna vara hämtat från rasbiologins tid. Nu måste staten ta sitt ansvar och börja agera som en demokratisk rättsstat, skriver 59 forskare.
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| 2. |
- Zamora, Juan Carlos, et al.
(författare)
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Considerations and consequences of allowing DNA sequence data as types of fungal taxa
- 2018
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Ingår i: IMA Fungus. - : INT MYCOLOGICAL ASSOC. - 2210-6340 .- 2210-6359. ; 9:1, s. 167-185
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Tidskriftsartikel (refereegranskat)abstract
- Nomenclatural type definitions are one of the most important concepts in biological nomenclature. Being physical objects that can be re-studied by other researchers, types permanently link taxonomy (an artificial agreement to classify biological diversity) with nomenclature (an artificial agreement to name biological diversity). Two proposals to amend the International Code of Nomenclature for algae, fungi, and plants (ICN), allowing DNA sequences alone (of any region and extent) to serve as types of taxon names for voucherless fungi (mainly putative taxa from environmental DNA sequences), have been submitted to be voted on at the 11th International Mycological Congress (Puerto Rico, July 2018). We consider various genetic processes affecting the distribution of alleles among taxa and find that alleles may not consistently and uniquely represent the species within which they are contained. Should the proposals be accepted, the meaning of nomenclatural types would change in a fundamental way from physical objects as sources of data to the data themselves. Such changes are conducive to irreproducible science, the potential typification on artefactual data, and massive creation of names with low information content, ultimately causing nomenclatural instability and unnecessary work for future researchers that would stall future explorations of fungal diversity. We conclude that the acceptance of DNA sequences alone as types of names of taxa, under the terms used in the current proposals, is unnecessary and would not solve the problem of naming putative taxa known only from DNA sequences in a scientifically defensible way. As an alternative, we highlight the use of formulas for naming putative taxa (candidate taxa) that do not require any modification of the ICN.
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| 3. |
- El Gohary, Fouad, et al.
(författare)
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Evaluating user understanding and exposure effects of demand-based tariffs
- 2022
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Ingår i: Renewable & sustainable energy reviews. - : Elsevier. - 1364-0321 .- 1879-0690. ; 155
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Tidskriftsartikel (refereegranskat)abstract
- Conventionally, demand response functions by communicating to electricity users through price signals embedded in their tariffs. These signals are intended to encourage a change in behavior, which hinges on the ability of users to understand their tariff and link it to the appropriate curtailment actions. This study focuses on demand-based tariffs, evaluating user's understanding of these tariffs and the conceptual grasp of power (rate of energy consumption) that they implicitly require. It also explores whether users exposed to these tariffs for extended periods develop a better understanding of them. Using a survey, the following points are sequentially evaluated: (1) Respondents' abilities to intuitively distinguish between energy/power (2) Their understanding of the different effects of curtailment actions under four distinct tariffs (3) Whether those subject to demand-based pricing outperform those subject to energy-based pricing. Despite a weaker conceptual understanding of power compared to energy, there were no significant differences between respondents' understanding of energy and demand-based tariffs. Comparing those subject to energy and demand-based pricing reveals that a majority were unaware of their own tariff (and hence which group they fall into), but for the minority of users who correctly identified their own tariffs, those subject to demand-based pricing outperform their energy-based counterparts. When presented with clear and instructive tariffs, respondents are largely able to deduce the consequences of curtailment actions, despite a weak conceptual understanding of power. A deeper problem is that the price signal may be entirely disregarded by an apathetic majority, reaching only an inquisitive minority.
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| 4. |
- El Gohary, Fouad, et al.
(författare)
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Getting the signal : Do electricity users meet the preconditions for making informed decisions on demand response?
- 2023
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Ingår i: Energy Research & Social Science. - : Elsevier. - 2214-6296 .- 2214-6326. ; 100
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Tidskriftsartikel (refereegranskat)abstract
- Demand response refers to changes in power consumption by electricity users in response to certain conditions on the electricity market. Anticipated to play a major role in the energy transition, demand response is conventionally exercised through network tariffs, which serve as a medium for price signals intended to incentivize and guide electricity users on how to best behave. Considerable attention has been devoted to the unresolved question of whether users are willing to respond to these signals, a question premised on the implicit assumption of cognizant users making informed decisions. Less attention has been dedicated to evaluating the validity of this assumption, and the extent to which users actually internalize these signals prior to making any decision on how to respond. This study posits that prior to making an informed decision on how to act, an electricity user must first “qualify” through meeting a set of preconditions. These preconditions are captured by a proposed three-stage framework that involves i) receiving the price signal (being aware of the tariff), ii) processing the price signal (comprehending its features) and iii) assimilating the price signal (understanding how behavior influences costs). Evaluating this framework using a survey, the study finds that only 3.8–8.5 % of respondents clear all three stages. This minority is substantially more likely to contain older villa-residents, who are comparatively more concerned with their costs and read their bills more frequently. The findings of this study demonstrate that the “audience” of tariff-based price signals are a small fraction of what is commonly supposed, and that research and policy should shift from a dominant focus on the magnitude of these price signals, towards alternative or improved strategies for communication and engagement.
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| 5. |
- Jakobsson Larsson, Birgitta, 1965-
(författare)
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Quality of life, Coping and need for Support during the ALS disease trajectory
- 2016
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The overall aim of this thesis was to investigate quality of life, coping and emotional distress (i.e. anxiety and depression) among newly diagnosed ALS patients. An additional aim was also to investigate relatives’ experiences of the care for the patient and the support they received for themselves during the disease progression.The most nominated areas of importance for the patient’s overall QoL were family, friends and own physical health. Most patients rated their QoL as good, which did not change at subsequent measurement, despite their physical function having changed for the worse during disease progression. Some patients had symptoms of clinical anxiety and depression during the first year after diagnosis. The total quality of life score did not correlate with physical function but with depression early on after diagnosis. Most patients used support and independence as strategies to cope with the disease during the first six months after diagnosis. There were few changes early on after the diagnosis, and the patients used several different strategies. The results show that the use of coping strategies remained stable over time. Both physical function and emotional distress correlated significant with different coping strategies, with some variation during the disease progression. Relatives experienced the care of their loved one as positive and based on the patient’s needs and desires. The treatment, knowledge, support and help from the staff were important for the relatives’ feeling of security. Different factors influence the use of support for themselves. The relatives did not think of their own needs, but their focus was rather on the patient.The results of the thesis highlight the importance of providing support both to patients and their relatives during the disease progression. With early and regular evaluation on quality of life, coping and emotional well-being among the patients, the health professionals may be able to support the patients based on their specific needs, which probably will increase their quality of life.
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| 6. |
- Kasparaviciute, Gabriele, 1990, et al.
(författare)
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Online Encoder-decoder Anomaly Detection using Encoder-decoder Architecture with Novel Self-configuring Neural Networks & Pure Linear Genetic Programming for Embedded Systems
- 2019
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Ingår i: Proceedings of the 11th International Joint Conference on Computational Intelligence - Volume 1: ECTA, 163-171, 2019 , Vienna, Austria. s. 163-171. - : SCITEPRESS - Science and Technology Publications. - 9789897583841
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Konferensbidrag (refereegranskat)abstract
- Recent anomaly detection techniques locus on the use of neural networks and an encoder-decoder architecture. However, these techniques lead to trade offs if implemented in an embedded environment such as high heat management, power consumption and hardware costs. This paper presents two related new methods for anomaly detection within data sets gathered from an autonomous mini-vehicle with a CAN bus. The first method which to the best of our knowledge is the first use of encoder-decoder architecture for anomaly detection using linear genetic programming (LGP). Second method uses self-configuring neural network that is created using evolutionary algorithm paradigm learning both architecture and weights suitable for embedded systems. Both approaches have the following advantages: it is inexpensive regarding resource use, can be run on almost any embedded board due to linear register machine advantages in computation. The proposed methods are also faster by at least one order of magnitude, and it includes both inference and complete training.
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| 7. |
- Kasparaviciute, Gabriele, 1990, et al.
(författare)
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Plastic grabber: Underwater autonomous vehicle simulation for plastic objects retrieval using genetic programming
- 2019
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Ingår i: Lecture Notes in Business Information Processing. - Cham : Springer International Publishing. - 1865-1356 .- 1865-1348. ; 339, s. 527-533
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Konferensbidrag (refereegranskat)abstract
- We propose a path planning solution using genetic programming for an autonomous underwater vehicle. Developed in ROS Simulator that is able to roam in an environment, identify a plastic object, such as bottles, grab it and retrieve it to the home base. This involves the use of a multi-objective fitness function as well as reinforcement learning, both required for the genetic programming to assess the model’s behaviour. The fitness function includes not only the objective of grabbing the object but also the efficient use of stored energy. Sensors used by the robot include a depth image camera, claw and range sensors that are all simulated in ROS.
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| 8. |
- Nordin, Jessika, et al.
(författare)
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Association of Protective HLA-A With HLA-B∗27 Positive Ankylosing Spondylitis
- 2021
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Ingår i: Frontiers in Genetics. - Lausanne, Switzerland : Frontiers Media S.A.. - 1664-8021. ; 12
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: To further elucidate the role of the MHC in ankylosing spondylitis by typing 17 genes, searching for HLA-B∗27 independent associations and assessing the impact of sex on this male biased disease.Methods: High-confidence two-field resolution genotyping was performed on 310 cases and 2196 controls using an n-1 concordance method. Protein-coding variants were called from next-generation sequencing reads using up to four software programs and the consensus result recorded. Logistic regression tests were applied to the dataset as a whole, and also in stratified sets based on sex or HLA-B∗27 status. The amino acids driving association were also examined.Results: Twenty-five HLA protein-coding variants were significantly associated to disease in the population. Three novel protective associations were found in a HLA-B∗27 positive population, HLA-A∗24:02 (OR = 0.4, CI = 0.2–0.7), and HLA-A amino acids Leu95 and Gln156. We identified a key set of seven loci that were common to both sexes, and robust to change in sample size. Stratifying by sex uncovered three novel risk variants restricted to the female population (HLA-DQA1∗04.01, -DQB1∗04:02, -DRB1∗08:01; OR = 2.4–3.1). We also uncovered a set of neutral variants in the female population, which in turn conferred strong effects in the male set, highlighting how population composition can lead to the masking of true associations.Conclusion: Population stratification allowed for a nuanced investigation into the tightly linked MHC region, revealing novel HLA-B∗27 signals as well as replicating previous HLA-B∗27 dependent results. This dissection of signals may help to elucidate sex biased disease predisposition and clinical progression.
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