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- Wamala, Sarah, et al.
(författare)
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Lipid profile and socioeconomic status in healthy middle aged women in Sweden
- 1997
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Ingår i: Journal of Epidemiology and Community Health. - : BMJ Publishing Group. - 0143-005X .- 1470-2738. ; 51:4, s. 400-407
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Tidskriftsartikel (refereegranskat)abstract
- Study objective - To examine the relationship between socioeconomic status (SES) and full lipid profile in middle aged healthy women. Participants - These comprised 300 healthy Swedish women between 30 and 65 years who constitute the control group of the Stockholm female coronary risk study, a population based, case-control study of women with coronary heart disease (CHD). The age matched control group, drawn from the census register of greater Stockholm, was representative of healthy Swedish women aged 30-65 years. Five measures of SES were used; educational level, occupation, decision latitude at work, annual income, and size of house or apartment. Main results - Swedish women with low decision latitude at work, low income, low educational level, blue collar jobs, and who were living in small houses or apartments had an unhealthy lipid profile, suggesting an increased risk of CHD. Part of this social gradient in lipids was explained by an unhealthy lifestyle, but the lipid gradients associated with decision latitude at work and annual income were independent of these factors. Decision latitude, educational level, and annual income had the strongest associations with lipid profile. These associations were independent of age, menopausal status, smoking, sedentary lifestyle, alcohol consumption, obesity, excess abdominal fat, and unhealthy dietary habits. Of the lipid variables, low high density lipoprotein cholesterol (HDL) levels were most consistently associated with low SES. Conclusions - Decision latitude at work was the strongest SES predictor of HDL levels in healthy middle aged Swedish women, after simultaneous adjustment for other SES measures, age, and all lifestyle factors in the multivariable regression model.
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| 2. |
- OrthGomer, K, et al.
(författare)
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Lipoprotein(a) as a determinant of coronary heart disease in young women
- 1997
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Ingår i: Circulation. - NATL INST PSYCHOSOC FACTORS & HLTH,HUDDINGE,SWEDEN. DEACONESS HOSP,INST PREVENT CARDIOVASC DIS,BOSTON,MA. HARVARD UNIV,SCH PUBL HLTH,DEPT EPIDEMIOL,BOSTON,MA 02115. KAROLINSKA HOSP,DEPT CARDIOL,S-10401 STOCKHOLM,SWEDEN. KAROLINSKA HOSP,DEPT THORAC RADIOL,S-10401 STOCKHOLM,SWEDEN. UNIV TEXAS,DIV CARDIOL,HOUSTON,TX. : AMER HEART ASSOC. - 0009-7322 .- 1524-4539. ; 95:2, s. 329-334
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Tidskriftsartikel (refereegranskat)abstract
- Background Lipoprotein(a) [Lp(a)] appears to be a risk factor for coronary heart disease (CHD) in men. The role of Lp(a) in women, however, is less clear. Methods and Results We examined the ability of Lp(a) to predict CHD in a population-based case-control study of women 65 years of age or younger who lived in the greater Stockholm area. Subjects were all patients hospitalized for an acute CHD event between February 1991 and February 1994. Control subjects were randomly selected from the city census and were matched to patients by age and catchment area. Lp(a) was measured 3 months after hospitalization by use of an immunoturbidometric method (Incstar) calibrated to the Northwest Lipid Research Laboratories (coefficient of variation was <9%). Of the 292 consecutive patients, 110 (37%) were hospitalized for an acute myocardial infarction, and 182 were hospitalized (63%) for angina pectoris. The mean age for both patients and control subjects was 56+/-7 years. Of participants, 74 patients (25%) and 84 control subjects (29%) were premenopausal. The distributions of Lp(a) were highly skewed in both patients and control subjects, with a range from 0.001 to 1.14 g/L. Age-adjusted odds ratio for CHD in the highest versus the lowest quartile of Lp(a) was 2.3 (95% confidence interval [CI], 1.4 to 3.7). After adjustment for age, smoking, education, body mass index, systolic blood pressure, total cholesterol, triglycerides, and HDL, the odds ratio was 2.9 (95% CI, 1.6 to 5.0). The odds ratios were similar when myocardial infarction and angina patients were compared with their respective control subjects. The odds ratios were 5.1 (95% CI, 1.4 to 18.4) and 2.4 (95% CI, 1.3 to 4.5) in premenopausal and postmenopausal women, respectively. Conclusions These results suggest that Lp(a) is a determinant of CHD in both premenopausal and postmenopausal women.
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| 3. |
- Al-Khalili, F, et al.
(författare)
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Clinical predictors of poor outcome in women recovering from acute coronary syndrome
- 2000
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Ingår i: Journal of the American College of Cardiology. - Karolinska Hosp, Dept Cardiol, S-10401 Stockholm, Sweden. Karolinska Hosp, Dept Publ Hlth Sci, Div Prevent Med, S-10401 Stockholm, Sweden. Karolinska Hosp, Dept Thorac Radiol, S-10401 Stockholm, Sweden. Karolinska Inst, Stockholm, Sweden. : ELSEVIER SCIENCE INC. - 0735-1097 .- 1558-3597. ; 35:2, s. 392A-392A
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 4. |
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| 5. |
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| 6. |
- Wamala, S.P, et al.
(författare)
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Determinants of obesity in relation to socioeconomic status among middle-aged Swedish women
- 1997
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Ingår i: Preventive Medicine. - : Elsevier BV. - 0091-7435 .- 1096-0260. ; 26:5 I, s. 734-744
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Tidskriftsartikel (refereegranskat)abstract
- Background. It has been previously demonstrated that obesity is common among women with low socioeconomic status (SES), but the factors accounting for this association are not well known. According to our hypothesis, low SES is associated with psychosocial stress, an unhealthy lifestyle, and reproductive history, which may increase the likelihood of women with low SES to be overweight or obese. Methods. We examined overweight and obesity in relation to SES among 300 healthy women ages 30-65 years, who constitute the control group of the Stockholm Female Coronary Risk Study, a population- based case-control study of women with coronary heart disease. This control group was compared with a large population-based sample and found to be representative of healthy Swedish women ages 30-65 years. We used an aggregate of education and occupation as a measure of SES and defined overweight as body mass index (BMI) between 23.8 and 28.6 kg/m2 and obesity as BMI > 28.6 kg/m2. Results. Low SES was a strong determinant of overweight and obesity among middle-aged healthy Swedish women. The odds of being overweight or obese increased with lower social position. After adjustment for age, the odds ratios for overweight and obesity among women in a low vs high position were 2.2 [95% confidence interval (CI) 1.1 to 4.4) and 2.7 (95% CI 1.1 to 6.7), respectively. Both low social position and obesity were related to reproductive history (higher parity and earlier age at menarche), unhealthy dietary habits, and unfavorable psychosocial factors (poor quality of life, low self-esteem, and job strain). These factors together explained 53% of the low. SES-obesity association. Conclusions. Reproductive history, unhealthy dietary habits, and psychosocial stress accounted for a large part of the association between low SES and obesity. Dietary habits and psychosocial stress are potentially modifiable factors, which should be taken into account in intervention programs among women with low SES.
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| 8. |
- Horsten, M, et al.
(författare)
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Depressive symptoms, social support, and lipid profile in healthy middle-aged women
- 1997
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Ingår i: Psychosomatic Medicine. - KAROLINSKA INST, DEPT PUBL HLTH SCI, DIV PREVENT MED, S-14157 HUDDINGE, SWEDEN. TILBURG UNIV, DEPT PSYCHOL, NL-5000 LE TILBURG, NETHERLANDS. : LIPPINCOTT WILLIAMS & WILKINS. - 0033-3174 .- 1534-7796. ; 59:5, s. 521-528
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Several studies have reported an inverse relationship between cholesterol levels and death from violent causes, including suicide. Because depression and depressive symptoms are associated with suicide and trauma, the relation between cholesterol and depressive symptoms is of interest. The objective of the present study was to examine this relationship in a group of healthy women. The second main objective of the study was to investigate the association between cholesterol and other psychosocial factors (social support, Vital exhaustion, and stressful life-events), which are known to be related to depression. Method: The study group consisted of 300 healthy women raged 31 to 65 years who were representative of women living in the greater Stockholm area. Depressive symptoms were measured by a nine-item questionnaire derived from Pearlin. For the measurement of social support a modified version of the Interview Schedule for Social Interaction was used. Health behaviors were measured by means of standard questionnaires. Lipids were analyzed by enzymatic and immunoturbidometric methods. Results: Women with a low serum cholesterol, defined as the lowest tenth of the cholesterol distribution (less than or equal to 4.7 mmol/1), reported significantly more depressive symptoms. In addition, depressive symptoms showed a significant inverse linear association with high-density lipoprotein (HDL). In multivariate models, which adjusted for smoking, alcohol consumption, exercise habits, body-mass index, waist-hip ratio, menopausal status, age, and educational level, these associations remained significant. In addition, when analyzed in relation to other psychosocial factors, low cholesterol was found to be strongly associated with lack of social support. This association was not explained by depressive symptoms. Conclusions: Low cholesterol levels in middle-aged healthy Swedish women were associated with a higher prevalence of depressive symptoms and with lack of social support. These findings may constitute a possible mechanism for the association found between low cholesterol and increased mortality, particularly suicide.
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| 11. |
- THEORELL, T, et al.
(författare)
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ENDOCRINE MARKERS DURING A JOB INTERVENTION
- 1995
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Ingår i: WORK AND STRESS. - : Informa UK Limited. - 0267-8373 .- 1464-5335. ; 9:1, s. 67-76
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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