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Sökning: WFRF:(Persson Daniel 1978)

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1.
  • Ahlén, Olof, et al. (författare)
  • Fourier coefficients attached to small automorphic representations of SLn (A)
  • 2018
  • Ingår i: Journal of Number Theory. - : Elsevier BV. - 0022-314X .- 1096-1658. ; 192, s. 80-142
  • Tidskriftsartikel (refereegranskat)abstract
    • We show that Fourier coefficients of automorphic forms attached to minimal or next-to-minimal automorphic representations of SLn(A) are completely determined by certain highly degenerate Whittaker coefficients. We give an explicit formula for the Fourier expansion, analogously to the Piatetski-Shapiro–Shalika formula. In addition, we derive expressions for Fourier coefficients associated to all maximal parabolic subgroups. These results have potential applications for scattering amplitudes in string theory.
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2.
  • Alexandrov, Sergei, et al. (författare)
  • Wall-crossing, Rogers dilogarithm and the QK/HK correspondence
  • 2011
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2011:12, s. 027-
  • Tidskriftsartikel (refereegranskat)abstract
    • When formulated in twistor space, the D-instanton corrected hypermultiplet moduli space in N=2 string vacua and the Coulomb branch of rigid N=2 gauge theories on R^3 x S^1 are strikingly similar and, to a large extent, dictated by consistency with wall-crossing. We elucidate this similarity by showing that these two spaces are related under a general duality between, on one hand, quaternion-Kahler manifolds with a quaternionic isometry and, on the other hand, hyperkahler manifolds with a rotational isometry, further equipped with a hyperholomorphic circle bundle with a connection. We show that the transition functions of the hyperholomorphic circle bundle relevant for the hypermultiplet moduli space are given by the Rogers dilogarithm function, and that consistency across walls of marginal stability is ensured by the motivic wall-crossing formula of Kontsevich and Soibelman. We illustrate the construction on some simple examples of wall-crossing related to cluster algebras for rank 2 Dynkin quivers. In an appendix we also provide a detailed discussion on the general relation between wall-crossing and the theory of cluster algebras.
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3.
  • Andersson, Henrik, et al. (författare)
  • Apoptotic neutrophils augment the inflammatory response to Mycobacterium tuberculosis infection in human macrophages
  • 2014
  • Ingår i: PLOS ONE. - : PLOS. - 1932-6203. ; 9:7
  • Tidskriftsartikel (refereegranskat)abstract
    • Macrophages in the lung are the primary cells being infected by Mycobacterium tuberculosis (Mtb) during the initial manifestation of tuberculosis. Since the adaptive immune response to Mtb is delayed, innate immune cells such as macrophages and neutrophils mount the early immune protection against this intracellular pathogen. Neutrophils are short-lived cells and removal of apoptotic cells by resident macrophages is a key event in the resolution of inflammation and tissue repair. Since anti-inflammatory activity is not compatible with effective immunity to intracellular pathogens, we therefore investigated how uptake of apoptotic neutrophils modulates the function of Mtb-activated human macrophages. We show that Mtb infection exerts a potent proinflammatory activation of human macrophages with enhanced gene activation and release of proinflammatory cytokines and that this response was augmented by apoptotic neutrophils. The enhanced macrophage response is linked to apoptotic neutrophil-driven activation of the NLRP3 inflammasome and subsequent IL-1β signalling. We also demonstrate that apoptotic neutrophils not only modulate the inflammatory response, but also enhance the capacity of infected macrophages to control intracellular growth of virulent Mtb. Taken together, these results suggest a novel role for apoptotic neutrophils in the modulation of the macrophage-dependent inflammatory response contributing to the early control of Mtb infection.
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4.
  • Ask, Per, 1978- (författare)
  • Invasion of top and intermediate consumers in a size structured fish community
  • 2010
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • In this thesis I have investigated the effects of invading top and intermediate consumers in a size-structured fish community, using a combination of field studies, a lake invasion experiment and smaller scale pond and aquaria experiments. The lake invasion experiment was based on introductions of an intermediate consumer, ninespine stickleback (Pungitius pungitius L.), in to allopatric populations of an omnivorous top predator, Arctic char (Salvelinus alpinus L.). The invasion experiment was performed in two tundra lakes and in two birch forest lakes to investigate the effect of climate on the invasion success. I found that the effect of sticklebacks on char was size dependent. Small char suffered reduced growth from resource competition with sticklebacks whereas the maximum size of adult char increased from the addition of a larger prey resource, stickleback. The negative effect of sticklebacks on the growth of small char suggests that sticklebacks may be a better resource competitor than char, which was also supported by the pond and aquaria experiments. The pond experiments also suggested that char were more efficient cannibals than interspecific predators on sticklebacks. Cannibalism in char may limit the recruitment of char and decrease both their predatory and competitive effect on coexisting species and thereby also promote the coexistence of char and sticklebacks. The successful invasion by sticklebacks and their subsequent increases in density suggest that the absence of sticklebacks in char lakes in this region is not caused by biotic interactions with char. Instead, it may be suggested that co-occurrence of sticklebacks and char in the region is limited by dispersal. The char – stickleback system resembles an intraguild predation system with char as the top consumer and stickleback as the intermediate consumer. The effects of the stickleback invasion is also contrasted with a field study of a northern pike (Esox lucius L.) invasion into a system with coexisting char and stickleback, where pike can be viewed as the top consumer and char as the intermediate consumer both feeding on sticklebacks. In this case pike excluded char. The identity of the invading species and the relative strength of the predatory and competitive interactions in the two contrasting systems are discussed in relation to coexistence in intraguild predation systems. I found that the identity of the invading species is of crucial importance for the response at the ecosystem level, and that the inherent size dependency of competitive and predatory interactions in fish communities is important for attaining a mechanistical understanding of the effects of invasive species in lake ecosystems.
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5.
  • Berg, Marcus, 1973-, et al. (författare)
  • Massive theta lifts
  • 2023
  • Ingår i: Journal of High Energy Physics (JHEP). - : Springer. - 1126-6708 .- 1029-8479. ; 2023:5
  • Tidskriftsartikel (refereegranskat)abstract
    • We use Poincaré series for massive Maass-Jacobi forms to define a “massive theta lift”, and apply it to the examples of the constant function and the modular invariant j-function, with the Siegel-Narain theta function as integration kernel. These theta integrals are deformations of known one-loop string threshold corrections. Our massive theta lifts fall off exponentially, so some Rankin-Selberg integrals are finite without Zagier renormalization.
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6.
  • Berg, M., et al. (författare)
  • Massive theta lifts
  • 2023
  • Ingår i: Journal of High Energy Physics. - 1029-8479. ; :5
  • Tidskriftsartikel (refereegranskat)abstract
    • We use Poincare series for massive Maass-Jacobi forms to define a "massive theta lift", and apply it to the examples of the constant function and the modular invariant j-function, with the Siegel-Narain theta function as integration kernel. These theta integrals are deformations of known one-loop string threshold corrections. Our massive theta lifts fall off exponentially, so some Rankin-Selberg integrals are finite without Zagier renormalization.
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7.
  • Berman, Robert, 1976, et al. (författare)
  • Emergent Sasaki-Einstein geometry and AdS/CFT
  • 2022
  • Ingår i: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723 .- 2041-1723. ; 13:1
  • Tidskriftsartikel (refereegranskat)abstract
    • A central problem in any quantum theory of gravity is to explain the emergence of the classical spacetime geometry in some limit of a more fundamental, microscopic description of nature. The gauge/gravity-correspondence provides a framework in which this problem can, in principle, be addressed. This is a holographic correspondence which relates a supergravity theory in five-dimensional Anti-deSitter space to a strongly coupled superconformal gauge theory on its 4-dimensional flat Minkowski boundary. In particular, the classical geometry should therefore emerge from some quantum state of the dual gauge theory. Here we confirm this by showing how the classical metric emerges from a canonical state in the dual gauge theory. In particular, we obtain approximations to the Sasaki-Einstein metric underlying the supergravity geometry, in terms of an explicit integral formula involving the canonical quantum state in question. In the special case of toric quiver gauge theories we show that our results can be computationally simplified through a process of tropicalization.
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8.
  • Bojan, Alicja J., 1980, et al. (författare)
  • A new bone adhesive candidate- does it work in human bone? An ex-vivo preclinical evaluation in fresh human osteoporotic femoral head bone
  • 2022
  • Ingår i: Injury-International Journal of the Care of the Injured. - : Elsevier BV. - 0020-1383 .- 1879-0267. ; 53:6, s. 1858-1866
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: The fixation of small intraarticular bone fragments is clinically challenging and an obvious first orthopaedic indication for an effective bone adhesive. In the present study the feasibility of bonding freshly harvested human trabecular bone with OsStic(R), a novel phosphoserine modified cement, was evaluated using a bone cylinder model pull-out test and compared with a commercial fibrin tissue adhesive. Methods: Femoral heads (n=13) were collected from hip fracture patients undergoing arthroplasty and stored refrigerated overnight in saline medium prior to testing. Cylindrical bone cores with a pre-inserted bone screw, were prepared using a coring tool. Each core was removed and glued back in place with either the bone adhesive (alpha-tricalcium phosphate, phosphoserine and 20% trisodium citrate solution) or the fibrin glue. All glued bones were stored in bone medium at 37 degrees C. Tensile loading, using a universal testing machine (5 kN load cell), was applied to each core/head. For the bone adhesive, bone cores were tested at 2 (n=13) and 24 (n=11) hours. For the fibrin tissue adhesive control group (n=9), bone cores were tested exclusively at 2 hours. The femoral bone quality was evaluated with micro-CT. Results: The ultimate pull-out load for the bone adhesive at 2 hours ranged from 36 to 171 N (mean 94 N, SD 42 N). At 24 hours the pull-out strength was similar, 47 to 198 N (mean 123 N, SD 43 N). The adhesive failure usually occurred through the adhesive layer, however in two samples, at 167 N and 198 N the screw pulled out of the bone core. The fibrin tissue adhesive group reached a peak force of 8 N maximally at 2 hours (range 2.8-8 N, mean 5.4 N, SD 1.6 N). The mean BV/TV for femoral heads was 0.15 and indicates poor bone quality. Conclusion: The bone adhesive successfully glued wet and fatty tissue of osteoporotic human bone cores. The mean ultimate pull-out force of 123 N at 24 hours corresponds to similar to 300 kPa shear stress acting on the bone core. These first ex-vivo results in human bone are a promising step toward potential clinical application in osteochondral fragment fixation. (C) 2022 The Authors. Published by Elsevier Ltd.
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9.
  • Boman, Christoffer, et al. (författare)
  • Development of innovative small(micro)-scale biomass-based CHP technologies
  • 2017
  • Rapport (övrigt vetenskapligt/konstnärligt)abstract
    • To enhance the overall efficiency of the use of biomass in the energy sector in Europe, the large electricity production potential from small-scale biomass heating systems should be utilised. So far, no technologically sound (in terms of efficiency and reliability) and economically affordable micro- and small-scale biomass CHP technologies are, however, available. Therefore, the present ERA-NET project (MiniBioCHP) aimed at the further development and test of new CHP technologies based on small-scale biomass combustion in the electric capacity range between some W and 100 kW. Within the project, an international consortium consisting of 12 partners from 4 countries, including university institutions, institutes and industry (both engineering and manufacturing), collaborated closely to perform high level R&D on three promising micro/small-scale biomass based CHP technologies which are covering a broad range of applications in the residential heating sector. The Austrian engineering company BIOS, coordinated the international project. The project was based on earlier basic research and development work related to these promising new technologies and aimed at the achievement of a technological level which allows a first (commercial) demonstration after the end of the project. The three CHP concepts included in the MiniBioCHP project were;1. Pellet stoves with a thermoelectric generator (TEG)2. Small-scale biomass boilers (10-30 kWth) with a micro-ORC process3. High temperature heat exchanger (HT-HE) for an externally fired gas turbine (EFGT)The Swedish part of the project was focused on the development of the concept of biomass based EFGT with dedicated R&D activities related to the development of the HT-HE system. The Swedish project consisted of the research partners Umeå University (project leader), Luleå University of Technology, Chalmers University of Technology and RISE Research Institutes of Sweden, together with the industrial partners Enertech AB/Osby Parca and Ecergy. The expertise of the Swedish partners regarding ash related problems, grate boiler combustion and modelling, deposit formation and high temperature corrosion, were combined with the know-how of a Polish partner regarding HT-HE design, construction, testing and optimisation.The HT-HE is the most crucial component in EFGT processes significantly influencing the investment costs, availabilities as well as the efficiencies that can be achieved. With a thermal capacity from several hundred kW up to 2-3 MWth) the CHP technology based on a biomass boiler and an EFGT is suitable for district heating systems, or process heat consumers. The electricity produced by the gas turbine (up to some 100 kWel) can be used to cover the own electricity consumption of a company and/or fed into the grid. Even though the concept of biomass based EFGT has been an interesting alternative for small-scale CHP production for some decades, and R&D activities have been undertaken, tackling both economic and technical aspects, only a few pilot-plants have been in operation and no initiative has so far reached the level of commercial implementation. Thus, the concept of EFGT fed with biomass is still considered to be in a rather early development stage and the main technical challenges are related to alkali deposit induced corrosion and thermal stress of the HT-HE material, turbine design/operation and system integration.Within the present project, a HT-HE prototype aimed for an EFGT system was therefore designed, constructed and successfully tested at flue gas temperatures up to 900°C. Thus, appropriate guidelines for a compact design of the HT-HE and recommendations have been worked out to minimize thermal stresses as well as ash related problems regarding ash deposit formation and high temperature corrosion in a biomass boiler system. Furthermore, different concepts for the overall biomass based EFGT system have been worked out and evaluated. The outcome of the project will hopefully be used in the further development work and form the basis for a first testing and demonstration plant within the coming years.
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10.
  • Carnerud, Daniel, 1983-, et al. (författare)
  • On the inclusion of sustainability and digitalisation in quality management : an overview from past to present
  • 2020
  • Ingår i: Total Quality Management and Business Excellence. - : Taylor & Francis. - 1478-3363 .- 1478-3371. ; , s. 1-23
  • Tidskriftsartikel (refereegranskat)abstract
    • The aim of this study is to explore whether trends in sustainability and digitalisation from the 1980s until today have left any significant practical or epistemological footprints on the quality management paradigm. The study design consists of a mixed-methods approach that applies a data-mining methodology and content analysis to the digital archives of eight scientific journals: six within the quality management (QM) domain and two with a focus on operations management (OM). The data set contains an unbroken time series of over 12,000 research paper abstracts, the first of them published in 1980, giving the study a coverage of almost 40 years. The findings show that sustainability came onto the scholarly scene in 1996 and has since become an increasingly popular research area. In regard to digitalisation, the story is quite different, as the concept is currently absent from the scholarly QM and OM literatures. However, a search for information technology (IT) and information systems (IS) revealed that these topics have been gaining attention since the 1980s. However, it was found that QM research only addresses one part of digitalisation, omitting several interesting dimensions. One example is that the QM and OM literatures address IS mainly in relation to standardised guidelines and business processes within organisations. At the same time, we found a handful of studies combining QM and topics related to modern digitisation, like social media. 
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11.
  • Fleig, Philipp, et al. (författare)
  • Eisenstein series and automorphic representations
  • 2015
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • We provide an introduction to the theory of Eisenstein series and automorphic forms on real simple Lie groups G, emphasising the role of representation theory. It is useful to take a slightly wider view and define all objects over the (rational) adeles A, thereby also paving the way for connections to number theory, representation theory and the Langlands program. Most of the results we present are already scattered throughout the mathematics literature but our exposition collects them together and is driven by examples. Many interesting aspects of these functions are hidden in their Fourier coefficients with respect to unipotent subgroups and a large part of our focus is to explain and derive general theorems on these Fourier expansions. Specifically, we give complete proofs of Langlands' constant term formula for Eisenstein series on adelic groups G(A) as well as the Casselman--Shalika formula for the p-adic spherical Whittaker vector associated to unramified automorphic representations of G(Q_p). Somewhat surprisingly, all these results have natural interpretations as encoding physical effects in string theory. We therefore introduce also some basic concepts of string theory, aimed toward mathematicians, emphasising the role of automorphic forms. In addition, we explain how the classical theory of Hecke operators fits into the modern theory of automorphic representations of adelic groups, thereby providing a connection with some key elements in the Langlands program, such as the Langlands dual group LG and automorphic L-functions. Our treatise concludes with a detailed list of interesting open questions and pointers to additional topics where automorphic forms occur in string theory.
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12.
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13.
  • Fleig, Philipp, et al. (författare)
  • Fourier expansions of Kac-Moody Eisenstein series and degenerate Whittaker vectors
  • 2014
  • Ingår i: Communications in Number Theory and Physics. - 1931-4531 .- 1931-4523. ; 8:1, s. 41-100
  • Tidskriftsartikel (refereegranskat)abstract
    • Motivated by string theory scattering amplitudes that are invariant under a discrete U-duality, we study Fourier coefficients of Eisenstein series on Kac-Moody groups. In particular, we analyse the Eisenstein series on E_9(R), E_10(R) and E_11(R) corresponding to certain degenerate principal series at the values s=3/2 and s=5/2 that were studied in 1204.3043. We show that these Eisenstein series have very simple Fourier coefficients as expected for their role as supersymmetric contributions to the higher derivative couplings R^4 and \partial^{4} R^4 coming from 1/2-BPS and 1/4-BPS instantons, respectively. This suggests that there exist minimal and next-to-minimal unipotent automorphic representations of the associated Kac-Moody groups to which these special Eisenstein series are attached. We also provide complete explicit expressions for degenerate Whittaker vectors of minimal Eisenstein series on E_6(R), E_7(R) and E_8(R) that have not appeared in the literature before.
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14.
  • Gaberdiel, Matthias R., et al. (författare)
  • Borcherds algebras and N=4 topological amplitudes
  • 2011
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2011:6, s. 125-
  • Tidskriftsartikel (refereegranskat)abstract
    • The perturbative spectrum of BPS-states in the E(8)xE(8) heterotic string theory compactified on T(2) is analysed. We show that the space of BPS-states forms a representation of a certain Borcherds algebra G which we construct explicitly using an auxiliary conformal field theory. The denominator formula of an extension G(ext) superset of G of this algebra is then found to appear in a certain heterotic one-loop N = 4 topological string amplitude. Our construction thus gives an N = 4 realisation of the idea envisioned by Harvey and Moore, namely that the 'algebra of BPS-states' controls the threshold corrections in the heterotic string.
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15.
  • Gaberdiel, Matthias R., et al. (författare)
  • Generalized Mathieu Moonshine
  • 2013
  • Ingår i: Communications in Number Theory and Physics. - 1931-4531 .- 1931-4523. ; 7:1, s. 145-223
  • Tidskriftsartikel (refereegranskat)abstract
    • The Mathieu twisted twining genera, i.e., the analogues of Norton's generalized Moonshine functions, are constructed for the elliptic genus of K3. It is shown that they satisfy the expected consistency conditions, and that their behaviour under modular transformations is controlled by a 3-cocycle in H-3(M-24, U(1)), just as for the case of holomorphic orbifolds. This suggests that a holomorphic VOA may be underlying Mathieu Moonshine.
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16.
  • Gerken, Jan, 1991, et al. (författare)
  • Equivariance versus augmentation for spherical images
  • 2022
  • Ingår i: Proceedings of Machine Learning Resaerch. ; , s. 7404-7421
  • Konferensbidrag (refereegranskat)abstract
    • We analyze the role of rotational equivariance in convolutional neural networks (CNNs) applied to spherical images. We compare the performance of the group equivariant networks known as S2CNNs and standard non-equivariant CNNs trained with an increasing amount of data augmentation. The chosen architectures can be considered baseline references for the respective design paradigms. Our models are trained and evaluated on single or multiple items from the MNIST- or FashionMNIST dataset projected onto the sphere. For the task of image classification, which is inherently rotationally invariant, we find that by considerably increasing the amount of data augmentation and the size of the networks, it is possible for the standard CNNs to reach at least the same performance as the equivariant network. In contrast, for the inherently equivariant task of semantic segmentation, the non-equivariant networks are consistently outperformed by the equivariant networks with significantly fewer parameters. We also analyze and compare the inference latency and training times of the different networks, enabling detailed tradeoff considerations between equivariant architectures and data augmentation for practical problems.
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17.
  • Gerken, Jan, 1991, et al. (författare)
  • Geometric deep learning and equivariant neural networks
  • 2023
  • Ingår i: Artificial Intelligence Review. - : Springer Nature. - 1573-7462 .- 0269-2821. ; 56:12, s. 14605-14662
  • Tidskriftsartikel (refereegranskat)abstract
    • We survey the mathematical foundations of geometric deep learning, focusing on group equivariant and gauge equivariant neural networks. We develop gauge equivariant convolutional neural networks on arbitrary manifolds M using principal bundles with structure group K and equivariant maps between sections of associated vector bundles. We also discuss group equivariant neural networks for homogeneous spaces M= G/ K , which are instead equivariant with respect to the global symmetry G on M . Group equivariant layers can be interpreted as intertwiners between induced representations of G, and we show their relation to gauge equivariant convolutional layers. We analyze several applications of this formalism, including semantic segmentation and object detection networks. We also discuss the case of spherical networks in great detail, corresponding to the case M= S2= SO (3) / SO (2) . Here we emphasize the use of Fourier analysis involving Wigner matrices, spherical harmonics and Clebsch–Gordan coefficients for G= SO (3) , illustrating the power of representation theory for deep learning.
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18.
  • Gourevitch, D., et al. (författare)
  • A reduction principle for Fourier coefficients of automorphic forms
  • 2022
  • Ingår i: Mathematische Zeitschrift. - : Springer Science and Business Media LLC. - 0025-5874 .- 1432-1823. ; 300, s. 2679-2717
  • Tidskriftsartikel (refereegranskat)abstract
    • We consider a special class of unipotent periods for automorphic forms on a finite cover of a reductive adelic groupG(AK), which we refer to as Fourier coefficients associated to the data of a 'Whittaker pair'. We describe a quasi-order on Fourier coefficients, and an algorithm that gives an explicit formula for any coefficient in terms of integrals and sums involving higher coefficients. The maximal elements for the quasi-order are 'Levi-distinguished' Fourier coefficients, which correspond to taking the constant term along the unipotent radical of a parabolic subgroup, and then further taking a Fourier coefficient with respect to a K-distinguished nilpotent orbit in the Levi quotient. Thus one can express any Fourier coefficient, including the form itself, in terms of higher Levi-distinguished coefficients. In companion papers we use this result to determine explicit Fourier expansions of minimal and next-to-minimal automorphic forms on split simply-laced reductive groups, and to obtain Euler product decompositions of certain Fourier coefficients.
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19.
  • Gourevitch, D., et al. (författare)
  • EULERIANITY OF FOURIER COEFFICIENTS OF AUTOMORPHIC FORMS
  • 2021
  • Ingår i: Representation Theory. - : American Mathematical Society (AMS). - 1088-4165. ; 25, s. 481-507
  • Tidskriftsartikel (refereegranskat)abstract
    • We study the question of Eulerianity (factorizability) for Fourier coefficients of automorphic forms, and we prove a general transfer theorem that allows one to deduce the Eulerianity of certain coefficients from that of another coefficient. We also establish a `hidden' invariance property of Fourier coefficients. We apply these results to minimal and next-to-minimal automorphic representations, and deduce Eulerianity for a large class of Fourier and Fourier-Jacobi coefficients. In particular, we prove Eulerianity for parabolic Fourier coefficients with characters of maximal rank for a class of Eisenstein series in minimal and next-to-minimal representations of groups of ADE-type that are of interest in string theory.
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20.
  • Gourevitch, Dmitry, et al. (författare)
  • Fourier coefficients of minimal and next-to-minimal automorphic representations of simply-laced groups
  • 2022
  • Ingår i: Canadian Journal of Mathematics. - 1496-4279 .- 0008-414X. ; 74:1, s. 122-169
  • Tidskriftsartikel (refereegranskat)abstract
    • In this paper, we analyze Fourier coefficients of automorphic forms on a finite cover G of an adelic split simply-laced group. Let ππ be a minimal or next-to-minimal automorphic representation of G. We prove that any η∈πη∈π is completely determined by its Whittaker coefficients with respect to (possibly degenerate) characters of the unipotent radical of a fixed Borel subgroup, analogously to the Piatetski-Shapiro–Shalika formula for cusp forms on GLnGLn . We also derive explicit formulas expressing the form, as well as all its maximal parabolic Fourier coefficient, in terms of these Whittaker coefficients. A consequence of our results is the nonexistence of cusp forms in the minimal and next-to-minimal automorphic spectrum. We provide detailed examples for G of type D5D5 and E8E8 with a view toward applications to scattering amplitudes in string theory.
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21.
  • Gustafsson, Henrik, 1988, et al. (författare)
  • Small automorphic representations and degenerate Whittaker vectors
  • 2016
  • Ingår i: Journal of Number Theory. - : Elsevier BV. - 0022-314X .- 1096-1658. ; 166, s. 344-399
  • Tidskriftsartikel (refereegranskat)abstract
    • We investigate Fourier coefficients of automorphic forms on split simply-laced Lie groups G. We show that for automorphic representations of small Gelfand-Kirillov dimension the Fourier coefficients are completely determined by certain degenerate Whittaker vectors on G. Although we expect our results to hold for arbitrary simply-laced groups, we give complete proofs only for G=SL(3) and G=SL(4). This is based on a method of Ginzburg that associates Fourier coefficients of automorphic forms with nilpotent orbits of G. Our results complement and extend recent results of Miller and Sahi. We also use our formalism to calculate various local (real and p-adic) spherical vectors of minimal representations of the exceptional groups E_6, E_7, E_8 using global (adelic) degenerate Whittaker vectors, correctly reproducing existing results for such spherical vectors obtained by very different methods.
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22.
  • Harrison, Sarah M., et al. (författare)
  • BPS Algebras in 2D String Theory
  • 2022
  • Ingår i: Annales Henri Poincare. - : Springer Science and Business Media LLC. - 1424-0637 .- 1424-0661. ; 23, s. 3667-3752
  • Tidskriftsartikel (refereegranskat)abstract
    • We discuss a set of heterotic and type II string theory compactifications to 1 + 1 dimensions that are characterized by factorized internal worldsheet CFTs of the form V1⊗ V¯ 2, where V1, V2 are self-dual (super) vertex operator algebras. In the cases with spacetime supersymmetry, we show that the BPS states form a module for a Borcherds–Kac–Moody (BKM) (super)algebra, and we prove that for each model the BKM (super)algebra is a symmetry of genus zero BPS string amplitudes. We compute the supersymmetric indices of these models using both Hamiltonian and path integral formalisms. The path integrals are manifestly automorphic forms closely related to the Borcherds–Weyl–Kac denominator. Along the way, we comment on various subtleties inherent to these low-dimensional string compactifications.
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23.
  • Harrison, Sarah M., et al. (författare)
  • Fun with F 24
  • 2021
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2021:2
  • Tidskriftsartikel (refereegranskat)abstract
    • We study some special features of F24, the holomorphic c = 12 superconformal field theory (SCFT) given by 24 chiral free fermions. We construct eight different Lie superalgebras of “physical” states of a chiral superstring compactified on F24, and we prove that they all have the structure of Borcherds-Kac-Moody superalgebras. This produces a family of new examples of such superalgebras. The models depend on the choice of an N = 1 supercurrent on F24, with the admissible choices labeled by the semisimple Lie algebras of dimension 24. We also discuss how F24, with any such choice of supercurrent, can be obtained via orbifolding from another distinguished c = 12 holomorphic SCFT, the N = 1 supersymmetric version of the chiral CFT based on the E8 lattice.
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24.
  • Harrison, S. M., et al. (författare)
  • Fun with F24
  • 2021
  • Ingår i: Journal of High Energy Physics. - 1029-8479. ; 2021:2
  • Tidskriftsartikel (refereegranskat)abstract
    • We study some special features of F24, the holomorphic c = 12 superconformal field theory (SCFT) given by 24 chiral free fermions. We construct eight different Lie superalgebras of “physical” states of a chiral superstring compactified on F24, and we prove that they all have the structure of Borcherds-Kac-Moody superalgebras. This produces a family of new examples of such superalgebras. The models depend on the choice of an N = 1 supercurrent on F24, with the admissible choices labeled by the semisimple Lie algebras of dimension 24. We also discuss how F24, with any such choice of supercurrent, can be obtained via orbifolding from another distinguished c = 12 holomorphic SCFT, the N = 1 supersymmetric version of the chiral CFT based on the E8 lattice. © 2021, The Author(s).
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25.
  • Hedbrant, Alexander, 1987-, et al. (författare)
  • Effects on white blood cell counts and the NLRP3 inflammasome due to dust and cobalt exposure in the hard metal industry
  • 2022
  • Ingår i: Biomarkers. - : Taylor & Francis. - 1354-750X .- 1366-5804. ; , s. 60-70
  • Tidskriftsartikel (refereegranskat)abstract
    • INTRODUCTION: In light of potential negative health effects of cobalt exposure, a characterization of inflammatory mechanisms in exposed individuals is warranted. The current study investigated cobalt exposure in the Swedish hard metal industry and its relationship to inflammatory markers, including NLRP3 inflammasome activation and white blood cell (WBC) counts.MATERIAL AND METHODS: Inhalable cobalt and dust exposures, and systemic cobalt levels, were determined for 72 workers in the hard metal industry and linear regression models were applied to correlate exposure to markers of inflammasome activation and WBC counts.RESULTS: Mean exposures to inhalable dust (0.11 mg/m3) and cobalt (0.0034 mg/m3) were below the Swedish occupational exposure limits, and these low exposures did not correlate with any investigated outcomes. Instead, cobalt blood levels significantly correlated with a ca 10% decrease in IL-18 plasma levels per 10 nM cobalt increase. Furthermore, pre-shift cobalt blood and/or urine levels significantly correlated with some WBC measures, including decreased neutrophil-to-lymphocyte ratio, increased lymphocyte-to-monocyte ratio, and lymphocyte counts.CONCLUSION: The low inhalable particle exposures had no impact on WBC counts and inflammasome activation. Instead, systemic cobalt levels, which also include skin exposure, demonstrated possible suppressive effects on inflammatory responses in cobalt-exposed individuals in the hard metal industry.
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26.
  • Hedbrant, Alexander, Ph.D, 1987-, et al. (författare)
  • Occupational quartz and particle exposure affect systemic levels of inflammatory markers related to inflammasome activation and cardiovascular disease
  • 2023
  • Ingår i: Environmental Health. - : BioMed Central (BMC). - 1476-069X. ; 22:1
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: The inflammatory responses are central components of diseases associated with particulate matter (PM) exposure, including systemic diseases such as cardiovascular diseases (CVDs). The aim of this study was to determine if exposure to PM, including respirable dust or quartz in the iron foundry environment mediates systemic inflammatory responses, focusing on the NLRP3 inflammasome and novel or established inflammatory markers of CVDs.METHODS: The exposure to PM, including respirable dust, metals and quartz were determined in 40 foundry workers at two separate occasions per worker. In addition, blood samples were collected both pre-shift and post-shift and quantified for inflammatory markers. The respirable dust and quartz exposures were correlated to levels of inflammatory markers in blood using Pearson, Kendall τ and mixed model statistics. Analyzed inflammatory markers included: 1) general markers of inflammation, including interleukins, chemokines, acute phase proteins, and white blood cell counts, 2) novel or established inflammatory markers of CVD, such as growth/differentiation factor-15 (GDF-15), CD40 ligand, soluble suppressor of tumorigenesis 2 (sST2), intercellular/vascular adhesion molecule-1 (ICAM-1, VCAM-1), and myeloperoxidase (MPO), and 3) NLRP3 inflammasome-related markers, including interleukin (IL)-1β, IL-18, IL-1 receptor antagonist (IL-1Ra), and caspase-1 activity.RESULTS: The average respirator adjusted exposure level to respirable dust and quartz for the 40 foundry workers included in the study was 0.65 and 0.020 mg/m3, respectively. Respirable quartz exposure correlated with several NLRP3 inflammasome-related markers, including plasma levels of IL-1β and IL-18, and several caspase-1 activity measures in monocytes, demonstrating a reverse relationship. Respirable dust exposure mainly correlated with non-inflammasome related markers like CXCL8 and sST2. CONCLUSIONS: The finding that NLRP3 inflammasome-related markers correlated with PM and quartz exposure suggest that this potent inflammatory cellular mechanism indeed is affected even at current exposure levels in Swedish iron foundries. The results highlight concerns regarding the safety of current exposure limits to respirable dust and quartz, and encourage continuous efforts to reduce exposure in dust and quartz exposed industries.
  •  
27.
  • Hedbrant, Alexander, 1987-, et al. (författare)
  • Quartz Dust Exposure Affects NLRP3 Inflammasome Activation and Plasma Levels of IL-18 and IL-1Ra in Iron Foundry Workers
  • 2020
  • Ingår i: Mediators of Inflammation. - : Hindawi Publishing Corporation. - 0962-9351 .- 1466-1861.
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: To study the association between inhalation of particulate matter or quartz in Swedish iron foundries and the effects on NLRP3 inflammasome activation. Methods: Particle exposure measurements were performed during an eight-hour work day for 85 foundry workers at three Swedish iron foundries. Personal sampling was used for measurement of respirable quartz and dust and stationary measurements to obtain exposure measurements for inhalable dust and PM10. The NLRP3 inflammasome markers, interleukin- (IL-) 1β and IL-18, and inhibitors IL-1 receptor antagonist (IL-1Ra) and IL-18 binding protein (IL-18BP) were measured in plasma. Inflammasome activation was measured by caspase-1 enzymatic activity in monocytes in whole blood by flow cytometry, and expression of inflammasome-related genes was quantified using real-time PCR. Multiple linear regression analysis was used to investigate associations between PM exposures and inflammatory markers. Sex, age, smoking, current infection, BMI, and single nucleotide polymorphism in the inflammasome regulating genes CARD8 (C10X) and NLRP3 (Q705K) were included as covariates. Results: The average exposure levels of respirable dust and quartz were 0.85 and 0.052 mg/m3, respectively. A significant exposure-response was found for respirable dust and IL-18 and for inhalable dust and IL-1Ra. Whole blood, drawn from study participants, was stimulated ex vivo with inflammasome priming stimuli LPS or Pam3CSK4, resulting in a 47% and 49% increase in caspase-1 enzymatic activity in monocytes. This increase in caspase-1 activity was significantly attenuated in the higher exposure groups for most PM exposure measures. Conclusions: The results indicate that exposure levels of PM in the iron foundry environment can affect the NLRP3 inflammasome and systemic inflammation.
  •  
28.
  • Henneaux, Marc, et al. (författare)
  • Coxeter group structure of cosmological billiards on compact spatial manifolds
  • 2008
  • Ingår i: Journal of High Energy Physics. - : Springer Science and Business Media LLC. - 1029-8479 .- 1126-6708. ; 2008:9, s. 49-
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a systematic study of the cosmological billiard structures of Einstein-p-form systems in which all spatial directions are compactified on a manifold of nontrivial topology. This is achieved for all maximally oxidised theories associated with split real forms, for all possible compactifications as defined by the de Rham cohomology of the internal manifold. In each case, we study the Coxeter group that controls the dynamics for energy scales below the Planck scale as well as the relevant billiard region. We compare and contrast them with the Weyl group and fundamental domain that emerge from the general BKL analysis. For generic topologies we find a variety of possibilities: ( i) The group may or may not be a simplex Coxeter group; ( ii) The billiard region may or may not be a fundamental domain. When it is not a fundamental domain, it can be described as a sequence of pairwise adjacent chambers, known as a gallery, and the reflections in the billiard walls provide a non-standard presentation of the Coxeter group. We find that it is only when the Coxeter group is a simplex Coxeter group, and the billiard region is a fundamental domain, that there is a correspondence between billiard walls and simple roots of a Kac-Moody algebra, as in the general BKL analysis. For each compactification we also determine whether or not the resulting theory exhibits chaotic dynamics.
  •  
29.
  • Hohenegger, S., et al. (författare)
  • Enhanced gauge groups in N=4 topological amplitudes and Lorentzian Borcherds algebras
  • 2011
  • Ingår i: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 2470-0010 .- 2470-0029. ; 84:10
  • Tidskriftsartikel (refereegranskat)abstract
    • We continue our study of algebraic properties of N = 4 topological amplitudes in heterotic string theory compactified on T(2), initiated in arXiv:1102.1821. In this work we evaluate a particular one-loop amplitude for any enhanced gauge group h subset of e(8) circle plus e(8), i.e. for arbitrary choice of Wilson line moduli. We show that a certain analytic part of the result has an infinite product representation, where the product is taken over the positive roots of a Lorentzian Kac-Moody algebra g(++). The latter is obtained through double extension of the complement g = (e(8) circle plus e(8))/h. The infinite product is automorphic with respect to a finite index subgroup of the full T-duality group SO(2, 18; Z) and, through the philosophy of Borcherds-Gritsenko-Nikulin, this defines the denominator formula of a generalized Kac-Moody algebra G(g(++)), which is an 'automorphic correction' of g(++). We explicitly give the root multiplicities of G(g(++)) for a number of examples.
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30.
  • Midtbö, Kristine, 1991-, et al. (författare)
  • Molecularly Distinct NLRP3 Inducers Mediate Diverse Ratios of Interleukin-1 β and Interleukin-18 from Human Monocytes
  • 2020
  • Ingår i: Mediators of Inflammation. - : Hindawi Publishing Corporation. - 0962-9351 .- 1466-1861. ; 2020
  • Tidskriftsartikel (refereegranskat)abstract
    • Inflammasomes cleave and activate interleukin- (IL-) 1β and IL-18 which have both shared and unique biological functions. IL-1β is an important mediator of the acute phase response to infections and tissue damage, whereas IL-18 takes part in activation and tailoring of the adaptive immune response. While IL-1β has served as the prototypic indicator of inflammasome activation, few studies have compared the potential differences in IL-1β and IL-18 production during inflammasome activation. Since these cytokines partake in different immune pathways, the involvement of inflammasome activity in different conditions needs to be described beyond IL-1β production alone. To address a potential heterogeneity in inflammasome functionality, ATP, chitosan, or silica oxide (SiO2) were used to induce NLRP3 inflammasome activation in THP-1 cells and the subsequent outcomes were quantified. Despite using doses of the inflammasome inducers yielding similar release of IL-1β, SiO2-stimulated cells showed a lower concentration of released IL-18 compared to ATP and chitosan. Hence, the cells stimulated with SiO2 responded with a distinctly different IL-18 : IL-1β ratio. The difference in the IL-18 : IL-1β ratio for SiO2 was constant over different doses. While all downstream responses were strictly dependent on a functional NLRP3 inflammasome, the differences did not depend on the level of gene expression, caspase-1 activity, or pyroptosis. We suggest that the NLRP3 inflammasome response should be considered a dynamic process, which can be described by taking the ratio between IL-1β and IL-18 into account and moving away from an on/off perspective of inflammasome activation.
  •  
31.
  • Nikaein, Niloofar, 1989-, et al. (författare)
  • Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation
  • 2023
  • Ingår i: Journal of Biological Chemistry. - : Elsevier. - 0021-9258 .- 1083-351X. ; 299:10
  • Tidskriftsartikel (refereegranskat)abstract
    • Inflammation is one of the vital mechanisms through which the immune system responds to harmful stimuli. During inflammation, pro and anti-inflammatory cytokines interplay to orchestrate fine-tuned, dynamic immune responses. The cytokine interplay governs switches in the inflammatory response and dictates the propagation and development of the inflammatory response. Molecular pathways underlying the interplay are complex, and time-resolved monitoring of mediators and cytokines is necessary as a basis to study them in detail. Our understanding can be advanced by mathematical models which enable to analyze the system of interactions and their dynamical interplay in detail. We, therefore, used a mathematical modeling approach to study the interplay between prominent pro and anti-inflammatory cytokines with a focus on tumor necrosis factor (TNF) and interleukin 10 (IL-10) in lipopolysaccharide (LPS)-primed primary human monocytes. Relevant time-resolved data were generated by experimentally adding or blocking IL-10 at different time points. The model was successfully trained and could predict independent validation data and was further used to perform simulations to disentangle the role of IL-10 feedbacks during an acute inflammatory event. We used the insight to obtain a reduced predictive model including only the necessary IL-10-mediated feedbacks. Finally, the validated reduced model was used to predict early IL-10 - TNF switches in the inflammatory response. Overall, we gained detailed insights into fine-tuning of inflammatory responses in human monocytes and present a model for further use in studying the complex and dynamic process of cytokine-regulated acute inflammation.
  •  
32.
  • Nilsson, Bengt E W, 1952, et al. (författare)
  • Instanton Corrections to the Universal Hypermultiplet and Automorphic Forms on SU(2,1).
  • 2010
  • Ingår i: Communications in Number Theory and Physics. - 1931-4531 .- 1931-4523. ; 4:1, s. 187-266
  • Tidskriftsartikel (refereegranskat)abstract
    • Abstract: The hypermultiplet moduli space in Type IIA string theory compactified on a rigid Calabi-Yau threefold X , corresponding to the “universal hypermultiplet”, is described at tree-level by the symmetric space SU(2,1)/(SU(2)×U(1)). To determine the quantum corrections to this metric, we posit that a discrete subgroup of the continuous tree-level isometry group SU(2,1), namely the Picard modular group SU(2,1;Z[i]), must remain un- broken in the exact metric – including all perturbative and non-perturbative quantum cor- rections. This assumption is expected to be valid when X admits complex multiplication by Z[i]. Based on this hypothesis, we construct an SU(2,1;Z[i])-invariant, non-holomorphic Eisenstein series, and tentatively propose that this Eisenstein series provides the exact contact potential on the twistor space over the universal hypermultiplet moduli space. We analyze its non-Abelian Fourier expansion, and show that the Abelian and non-Abelian Fourier coefficients take the required form for instanton corrections due to Euclidean D2- branes wrapping special Lagrangian submanifolds, and to Euclidean NS5-branes wrapping the entire Calabi-Yau threefold, respectively. While this tentative proposal fails to repro- duce the correct one-loop correction, the consistency of the Fourier expansion with physics expectations provides strong support for the usefulness of the Picard modular group in constraining the quantum moduli space.
  •  
33.
  • Nilsson, Bengt E W, 1952, et al. (författare)
  • Rigid Calabi-Yau threefolds, Picard Eisenstein series and instantons
  • 2010
  • Ingår i: roceedings of 6th International Symposium on Quantum Theory and Symmetries (QTS6), Lexington, Kentucky, 20-25 Jul 2009..
  • Konferensbidrag (refereegranskat)abstract
    • Abstract.Type IIA string theory compactified on a rigid Calabi-Yau threefold gives rise to a classical moduli space that carries an isometric action of U(2,1). Various quantum corrections break this continuous isometry to a discrete subgroup. Focussing on the case where the intermediate Jacobian of the Calabi-Yau admits complex multiplication by the ring of quadratic imaginary integers Od, we argue that the remaining quantum duality group is an arithmetic Picard modular group PU(2,1;Od). Based on this proposal we construct an Eisenstein series invariant under this duality group and study its non-Abelian Fourier expansion. This allows the prediction of non-perturbative effects, notably the contribution of D2- and NS5-brane instantons. The present work extends our previous analysis in 0909.4299 which was restricted to the special case of the Gaussian integers O1 = Z[i].
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34.
  • Nyman, Elin, et al. (författare)
  • Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling
  • 2020
  • Ingår i: CPT. - : John Wiley & Sons. - 2163-8306. ; 9:12, s. 707-717
  • Tidskriftsartikel (refereegranskat)abstract
    • Both initiation and suppression of inflammation are hallmarks of the immune response. If not balanced, the inflammation may cause extensive tissue damage, which is associated with common diseases, e.g. asthma and atherosclerosis. Anti-inflammatory drugs come with side-effects which may be aggravated by high and fluctuating drug concentrations. To remedy this, an anti-inflammatory drug should have an appropriate pharmacokinetic half-life or better still: a sustained anti-inflammatory drug response. However, we still lack a quantitative mechanistic understanding of such sustained effects. Here, we study the anti-inflammatory response to a common glucocorticoid drug, Dexamethasone. We find a sustained response 22 hours after drug removal. With hypothesis testing using mathematical modeling, we unravel the underlying mechanism - a slow release of Dexamethasone from the receptor-drug complex. The developed model is in agreement with time-resolved training and testing data, and is used to simulate hypothetical treatment schemes. This work opens up for a more knowledge-driven drug development, to find sustained anti-inflammatory responses and fewer side effects.
  •  
35.
  • Paquette, Natalie M., et al. (författare)
  • BPS algebras, genus zero and the heterotic Monster
  • 2017
  • Ingår i: Journal of Physics A: Mathematical and Theoretical. - : IOP Publishing. - 1751-8113 .- 1751-8121. ; 50
  • Tidskriftsartikel (refereegranskat)abstract
    • © 2017 IOP Publishing Ltd. In this note, we expand on some technical issues raised in (Paquette et al 2016 Commun. Number Theory Phys. 10 433-526) by the authors, as well as providing a friendly introduction to and summary of our previous work. We construct a set of heterotic string compactifications to 0 + 1 dimensions intimately related to the Monstrous moonshine module of Frenkel, Lepowsky, and Meurman (and orbifolds thereof). Using this model, we review our physical interpretation of the genus zero property of Monstrous moonshine. Furthermore, we show that the space of (second-quantized) BPS-states forms a module over the Monstrous Lie algebras - some of the first and most prominent examples of Generalized Kac-Moody algebras - constructed by Borcherds and Carnahan. In particular, we clarify the structure of the module present in the second-quantized string theory. We also sketch a proof of our methods in the language of vertex operator algebras, for the interested mathematician.
  •  
36.
  • Paquette, N. M., et al. (författare)
  • Monstrous BPS-algebras and the superstring origin of moonshine
  • 2016
  • Ingår i: Communications in Number Theory and Physics. - 1931-4531 .- 1931-4523. ; 10:3, s. 433-526
  • Tidskriftsartikel (refereegranskat)abstract
    • We provide a physics derivation of Monstrous moonshine. We show that the McKay-Thompson series T-g, g epsilon M, can be interpreted as supersymmetric indices counting spacetime BPS-states in certain heterotic string models. The invariance groups of these series arise naturally as spacetime T-duality groups and their genus zero property descends from the behaviour of these heterotic models in suitable decompactification limits. We also show that the space of BPS-states forms a module for the Monstrous Lie algebras m(g), constructed by Borcherds and Carnahan. We argue that m(g) arise in the heterotic models as algebras of spontaneously broken gauge symmetries, whose generators are in exact correspondence with BPS-states. This gives mg an interpretation as a kind of BPS-algebra.
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37.
  • Persson, Alexander, 1978-, et al. (författare)
  • Apoptotic neutrophils activates the inflammatory response in macrophages –increased capacity to handle intracellular infection
  • Annan publikation (populärvet., debatt m.m.)abstract
    • Inflammation is essential to eradicate invading pathogens but an uncontrolled inflammation may develop into chronic inflammation and extensive tissue destruction unable of effectively controlling infections. At the site of infection, macrophages are the major regulators of the inflammatory response through balanced release of pro- or anti-inflammatory cytokines and therefore a key cell in the resolution of inflammation. Neutrophils effectively phagocytose and kill pathogens but they are short-lived and removal of these dead cells by macrophages is a key event in the resolution of inflammation and tissue repair. However, down-regulation of the immune response by apoptotic cells would in the presence of pathogens be detrimental to the host. In contrast to resolution of inflammation, we show that in the presence of microbial stimuli, apoptotic neutrophils in fact exert a potent pro-inflammatory activation of macrophages. This augmentation of the pro-inflammatory response is dependent on uptake of the apoptotic cells by the macrophage. In addition to secretion of TNF-α, presence of apoptotic neutrophils enhanced the capacity of the stimulated macrophages to kill intracellular Mycobacterium tuberculosis. This presents a novel role for apoptotic neutrophils in the modulation of the macrophage-dependent inflammatory response, and control of intracellular infections.
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38.
  • Persson, Daniel, 1978 (författare)
  • Arithmetic and Hyperbolic Structures in String Theory
  • 2009
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • This thesis consists of an introductory text followed by two separate parts which may be read independently of each other. In Part I we analyze certain hyperbolic structures arising when studying gravity in the vicinity of spacelike singularities (the BKL-limit). In this limit, spatial points decouple and the dynamics exhibits ultralocal behaviour which may be mapped to an auxiliary problem given in terms of a (possibly chaotic) hyperbolic billiard. In all supergravities arising as low-energy limits of string theory or M-theory, the billiard dynamics takes place within the fundamental Weyl chambers of certain hyperbolic Kac-Moody algebras, suggesting that these algebras generate hidden infinite-dimensional symmetries of gravity. We investigate the modification of the billiard dynamics when the original gravitational theory is formulated on a compact spatial manifold of arbitrary topology, revealing fascinating mathematical structures known as galleries. We further use the conjectured hyperbolic symmetry E10 to generate and classify certain cosmological (S-brane) solutions in eleven-dimensional supergravity. Finally, we show in detail that eleven-dimensional supergravity and massive type IIA supergravity are dynamically unified within the framework of a geodesic sigma model for a particle moving on the infinite-dimensional coset space E10/K(E10). Part II of the thesis is devoted to a study of how (U-)dualities in string theory provide powerful constraints on perturbative and non-perturbative quantum corrections. These dualities are typically given by certain arithmetic groups G(Z) which are conjectured to be preserved in the effective action. The exact couplings are given by moduli-dependent functions which are manifestly invariant under G(Z), known as automorphic forms. We discuss in detail various methods of constructing automorphic forms, with particular emphasis on a special class of functions known as (non-holomorphic) Eisenstein series. We provide detailed examples for the physically relevant cases of SL(2,Z) and SL(3,Z), for which we construct their respective Eisenstein series and compute their (non-abelian) Fourier expansions. We also discuss the possibility that certain generalized Eisenstein series, which are covariant under the maximal compact subgroup K(G), could play a role in determining the exact effective action for toroidally compactified higher derivative corrections. Finally, we propose that in the case of rigid Calabi-Yau compactifications in type IIA string theory, the exact universal hypermultiplet moduli space exhibits a quantum duality group given by the Picard modular group SU(2,1;Z[i]). To verify this proposal we construct an SU(2,1;Z[i])-invariant Eisenstein series, and we present preliminary results for its Fourier expansion which reveals the expected contributions from D2-brane and NS5-brane instantons.
  •  
39.
  • Persson, Daniel, 1978 (författare)
  • Automorphic instanton partition functions on Calabi-Yau threefolds
  • 2012
  • Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 346:1, s. Art. no. 012016-
  • Konferensbidrag (refereegranskat)abstract
    • We survey recent results on quantum corrections to the hypermultiplet moduli space M in type IIA/B string theory on a compact Calabi-Yau threefold X, or, equivalently, the vector multiplet moduli space in type IIB/A on X × S 1. Our main focus lies on the problem of resumming the infinite series of D-brane and NS5-brane instantons, using the mathematical machinery of automorphic forms. We review the proposal that when the theory in three dimensions exhibits an arithmetic "U-duality" symmetry G(ℤ) the total instanton partition function arises from a certain unitary automorphic representation of G, whose Fourier coefficients reproduce the BPS-degeneracies. In the case of four-dimensional N = 2 theories on ℝ × S 1 we argue that the relevant automorphic representation falls in the quaternionic discrete series of G, and that the partition function is a holomorphic section on the twistor space Z over M.
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40.
  • Persson, Daniel, 1978, et al. (författare)
  • Dualities in CHL-models
  • 2018
  • Ingår i: Journal of Physics A: Mathematical and Theoretical. - : IOP Publishing. - 1751-8113 .- 1751-8121. ; 51
  • Tidskriftsartikel (refereegranskat)abstract
    • © 2018 IOP Publishing Ltd Printed in the UK. We define a very general class of CHL-models associated with any string theory S (bosonic or supersymmetric) compactified on an internal CFT C×T d . We take the orbifold by a pair (g,δ), where g is a (possibly nongeometric) symmetry of C and δis a translation along Tn. We analyze the T-dualities of these models and show that in general they contain Atkin-Lehner type symmetries. This generalizes our previous work on N = 4 CHLmodels based on heterotic string theory on T 6 or type II on K3 × T 2 , as well.
  •  
41.
  • Persson, Daniel, 1978, et al. (författare)
  • Finite and infinite-dimensional symmetries of pure N=2 supergravity in D=4
  • 2009
  • Ingår i: Journal of High Energy Physics. - : Springer Science and Business Media LLC. - 1029-8479 .- 1126-6708.
  • Tidskriftsartikel (refereegranskat)abstract
    • We study the symmetries of pure N=2 supergravity in D=4. As is known, this theory reduced on one Killing vector is characterised by a non-linearly realised symmetry SU(2,1) which is a non-split real form of SL(3,C). We consider the BPS brane solutions of the theory preserving half of the supersymmetry and the action of SU(2,1) on them. Furthermore we provide evidence that the theory exhibits an underlying algebraic structure described by the Lorentzian Kac-Moody group SU(2,1)^{+++}. This evidence arises both from the correspondence between the bosonic space-time fields of N=2 supergravity in D=4 and a one-parameter sigma-model based on the hyperbolic group SU(2,1)^{++}, as well as from the fact that the structure of BPS brane solutions is neatly encoded in SU(2,1)^{+++}. As a nice by-product of our analysis, we obtain a regular embedding of the Kac-Moody algebra su(2,1)^{+++} in e_{11} based on brane physics.
  •  
42.
  • Persson, Daniel, 1978, et al. (författare)
  • Fivebrane instantons, topological wave functions and hypermultiplet moduli spaces
  • 2011
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 1103, s. 111-
  • Tidskriftsartikel (refereegranskat)abstract
    • We investigate quantum corrections to the hypermultiplet moduli space M in Calabi-Yau compactifications of type II string theories, with particular emphasis on instanton effects from Euclidean NS5-branes. Based on the consistency of D- and NS5-instanton corrections, we determine the topology of the hypermultiplet moduli space at fixed string coupling, as previewed in arXiv:1009.3026. On the type IIB side, we compute corrections from (p,k)-fivebrane instantons to the metric on M (specifically, the correction to the complex contact structure on its twistor space Z) by applying S-duality to the D-instanton sum. For fixed fivebrane charge k, the corrections can be written as a non-Gaussian theta series, whose summand for k=1 reduces to the topological A-model amplitude. By mirror symmetry, instanton corrections induced from the chiral type IIA NS5-brane are similarly governed by the wave function of the topological B-model. In the course of this investigation we clarify charge quantization for coherent sheaves and find hitherto unnoticed corrections to the Heisenberg, monodromy and S-duality actions on M, as well as to the mirror map for Ramond-Ramond fields and D-brane charges.
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43.
  • Persson, Daniel, 1978, et al. (författare)
  • Fricke S-duality in CHL models
  • 2015
  • Ingår i: Journal of High Energy Physics. - 1029-8479 .- 1126-6708. ; 2015:12, s. 1-55
  • Tidskriftsartikel (refereegranskat)abstract
    • We consider four dimensional CHL models with sixteen spacetime supersymmetries obtained from orbifolds of type IIA superstring on K3×T 2 by a ℤ? symmetry acting (possibly) non-geometrically on K3. We show that most of these models (in particular, for geometric symmetries) are self-dual under a weak-strong duality acting on the heterotic axio-dilaton modulus S by a “Fricke involution” S → −1/NS. This is a novel symmetry of CHL models that lies outside of the standard SL(2,ℤ)-symmetry of the parent theory, heterotic strings on T 6. For self-dual models this implies that the lattice of purely electric charges is N-modular, i.e. isometric to its dual up to a rescaling of its quadratic form by N. We verify this prediction by determining the lattices of electric and magnetic charges in all relevant examples. We also calculate certain BPS-saturated couplings and verify that they are invariant under the Fricke S-duality. For CHL models that are not self-dual, the strong coupling limit is dual to type IIA compactified on ?6/ℤ?, for some ℤ?-symmetry preserving half of the spacetime supersymmetries.
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44.
  • Persson, Daniel, 1978, et al. (författare)
  • Generalised Moonshine and Holomorphic Orbifolds
  • 2015
  • Ingår i: Proceedings of Symposia in Pure Mathematics - Conference on String-Math 2012. - Providence, Rhode Island : American Mathematical Society. - 2324-707X. - 9780821894958 ; 90, s. 73-86
  • Konferensbidrag (refereegranskat)abstract
    • Generalised moonshine is reviewed from the point of view of holomorphic orbifolds, putting special emphasis on the role of the third cohomology group H^3(G, U(1)) in characterising consistent constructions. These ideas are then applied to the case of Mathieu moonshine, i.e. the recently discovered connection between the largest Mathieu group M_24 and the elliptic genus of K3. In particular, we find a complete list of twisted twining genera whose modular properties are controlled by a class in H^3(M_24, U(1)), as expected from general orbifold considerations.
  •  
45.
  • Persson, Daniel, 1978, et al. (författare)
  • Instanton Corrections to the Universal Hypermultiplet and Automorphic Forms on SU(2,1)
  • 2009
  • Ingår i: Preprint: arXiv:0909.4299 [hep-th]. ; , s. 55 pages-
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • The hypermultiplet moduli space in Type IIA string theory compactified on a rigid Calabi-Yau threefold X, corresponding to the "universal hypermultiplet", is described at tree-level by the symmetric space SU(2,1)/(SU(2) x U(1)). To determine the quantum corrections to this metric, we posit that a discrete subgroup of the continuous tree-level isometry group SU(2,1), namely the Picard modular group SU(2,1;Z[i]), must remain unbroken in the exact metric -- including all perturbative and non perturbative quantum corrections. This assumption is expected to be valid when X admits complex multiplication by Z[i]. Based on this hypothesis, we construct an SU(2,1;Z[i])-invariant, non-holomorphic Eisenstein series, and tentatively propose that this Eisenstein series provides the exact contact potential on the twistor space over the universal hypermultiplet moduli space. We analyze its non-Abelian Fourier expansion, and show that the Abelian and non-Abelian Fourier coefficients take the required form for instanton corrections due to Euclidean D2-branes wrapping special Lagrangian submanifolds, and to Euclidean NS5-branes wrapping the entire Calabi-Yau threefold, respectively. While this tentative proposal fails to reproduce the correct one-loop correction, the consistency of the Fourier expansion with physics expectations provides strong support for the utility of the Picard modular group in constraining the quantum moduli space.
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46.
  • Persson, Daniel, 1978, et al. (författare)
  • Massive Type IIA Supergravity and E10
  • 2009
  • Ingår i: Fortschritte der Physik. - : Wiley. - 0015-8208 .- 1521-3978. ; 57:5-7, s. 580-586
  • Tidskriftsartikel (refereegranskat)abstract
    • In this talk we investigate the symmetry under E10 of Romans' massive type IIA supergravity. We show that the dynamics of a spinning particle in a non-linear sigma model on the coset space E10/K(E10) reproduces the bosonic and fermionic dynamics of massive IIA supergravity, in the standard truncation. In particular, we identify Romans' mass with a generator of E10 that is beyond the realm of the generators of E10 considered in the eleven-dimensional analysis, but using the same, underformed sigma model. As a consequence, this work provides a dynamical unification of the massless and massive versions of type IIA supergravity inside E10.
  •  
47.
  • Persson, Daniel, 1978, et al. (författare)
  • On the E10/Massive Type IIA Supergravity Correspondence
  • 2009
  • Ingår i: Physical Review D - Particles, Fields, Gravitation and Cosmology. - 2470-0010 .- 2470-0029. ; 79:4, s. 045088-
  • Tidskriftsartikel (refereegranskat)abstract
    • In this paper we investigate in detail the correspondence between E10 and Romans' massive deformation of type IIA supergravity. We analyse the dynamics of a non-linear sigma model for a spinning particle on the coset space E10/K(E10) and show that it reproduces the dynamics of the bosonic as well as the fermionic sector of the massive IIA theory, within the standard truncation. The mass deformation parameter corresponds to a generator of E10 outside the realm of the generators entering the usual D=11 analysis, and is naturally included without any deformation of the coset model for E10/K(E10). Our analysis thus provides a dynamical unification of the massless and massive versions of type IIA supergravity inside E10. We discuss a number of additional and general features of relevance in the analysis of any deformed supergravity in the correspondence to Kac-Moody algebras, including recently studied deformations where the trombone symmetry is gauged.
  •  
48.
  • Persson, Daniel, 1978, et al. (författare)
  • On the topology of the hypermultiplet moduli space in type II/CY string vacua
  • 2011
  • Ingår i: Physical Review D. ; 83, s. 026001-
  • Tidskriftsartikel (refereegranskat)abstract
    • By analyzing qualitative aspects of NS5-brane instanton corrections, we determine the topology of the hypermultiplet moduli space M_H in Calabi-Yau compactifications of type II string theories at fixed value of the dilaton and of the Calabi-Yau metric. Specifically, we show that for fivebrane instanton couplings to be well-defined, translations along the intermediate Jacobian must induce non-trivial shifts of the Neveu-Schwarz axion which had thus far been overlooked. As a result, the Neveu-Schwarz axion parametrizes the fiber of a circle bundle, isomorphic to the one in which the fivebrane partition function is valued. In the companion paper arXiv:1010.5792, we go beyond the present analysis and take steps towards a quantitative description of fivebrane instanton corrections, using a combination of mirror symmetry, S-duality, topological string theory and twistor techniques.
  •  
49.
  • Persson, Daniel, 1978, et al. (författare)
  • Quantum hypermultiplet moduli spaces in N=2 string vacua: a review
  • 2015
  • Ingår i: Proceedings of Symposia in Pure Mathematics - Conference on String-Math 2012. - Providence, Rhode Island : American Mathematical Society. - 2324-707X. - 9780821894958 ; 90, s. 181-211
  • Konferensbidrag (refereegranskat)abstract
    • The hypermultiplet moduli space M_H in type II string theories compactified on a Calabi-Yau threefold X is largely constrained by supersymmetry (which demands quaternion-K\"ahlerity), S-duality (which requires an isometric action of SL(2, Z)) and regularity. Mathematically, M_H ought to encode all generalized Donaldson-Thomas invariants on X consistently with wall-crossing, modularity and homological mirror symmetry. We review recent progress towards computing the exact metric on M_H, or rather the exact complex contact structure on its twistor space.
  •  
50.
  • Persson, Daniel, 1978, et al. (författare)
  • Second-quantized Mathieu moonshine
  • 2014
  • Ingår i: Communications in Number Theory and Physics. - 1931-4531 .- 1931-4523. ; 8:3, s. 403-509
  • Tidskriftsartikel (refereegranskat)abstract
    • We study the second-quantized version of the twisted twining genera of generalized Mathieu moonshine, and prove that they give rise to Siegel modular forms with infinite product representations. Most of these forms are expected to have an interpretation as twisted partition functions counting 1/4 BPS dyons in type II superstring theory on K3 x T-2 or in heterotic CHL-models. We show that all these Siegel modular forms, independently of their possible physical interpretation, satisfy an "S-duality" transformation and a "wall-crossing formula". The latter reproduces all the eta-products of an older version of generalized Mathieu moonshine proposed by Mason in the 1990s. Surprisingly, some of the Siegel modular forms we find coincide with the multiplicative (Borcherds) lifts of Jacobi forms in umbral moonshine.
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