| 1. |
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| 2. |
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| 3. |
- Wilking, N., et al.
(författare)
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Long-term follow-up of the SBG 9401 study comparing tailored FEC-based therapy versus marrow-supported high-dose therapy
- 2007
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Ingår i: Annals of Oncology. - : Elsevier BV. - 0923-7534 .- 1569-8041. ; 18:4, s. 694-700
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Tidskriftsartikel (refereegranskat)abstract
- Background: The purpose was to investigate adjuvant marrow-supportive high-dose chemotherapy compared with an equitoxicity-tailored comparator arm. Patients and methods: Five hundred and twenty-five women below theage of 60 years with operated high-risk primary breast cancer were randomised to nine cycles of granulocyte colony-stimulating factor supported and individually tailored FEC (5-fluorouracil, epirubicin, cyclophosphamide), (n = 251) or standard FEC followed by marrow-supported high-dose therapy with CTCb (cyclophosphamide, thiotepa, carboplatin) therapy (n = 274), followed by locoregional radiotherapy and tamoxifen for 5 years. Results: There were 104 breast cancer relapses in the tailored FEC group versus 139 in the CTCb group (double triangular method by Whitehead, P = 0.046), with a median follow-up of all included patients of 60.8 months. The event-free survival demonstrated 121 and 150 events in the tailored FEC- and CTCb group, respectively [P = 0.074, hazard ratio (HR) 0.804, 95% confidence interval (CI) 0.633-1.022]. Ten patients in the tailored FEC regimen developed acute myeloid leukaemia (AML)/myelodysplasia (MDS). One hundred deaths occurred in the tailored FEC group and 121 in the CTCb group (P = 0.287, HR 0.866, 95% CI 0.665-1.129). Conclusion: The update of this study shows an improved outcome linked to the tailored FEC treatment in relation to breast cancer relapse, but also an increased incidence of AML/MDS. © 2007 Oxford University Press.
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| 4. |
- Brown, S A, et al.
(författare)
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Unresolved issues in prophylaxis
- 2002
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Ingår i: Haemophilia. - : Wiley. - 1351-8216. ; 8:6, s. 817-821
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Tidskriftsartikel (refereegranskat)
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| 5. |
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| 6. |
- Uher, J, et al.
(författare)
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Highly sensitive silicon detectors of thermal neutrons
- 2007
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Ingår i: Nuclear Science Symposium Conference Record, 2006. IEEE. Vol 3.. - : IEEE conference proceedings. - 1424405602 - 9781424405619 ; , s. 1346-1348
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Konferensbidrag (refereegranskat)abstract
- Planar semiconductor diodes supplemented with a layer of an appropriate neutron converter such as 6LiF can be used for thermal neutron counting or imaging. Neutrons interacting in the converter generate alphas and tritons which enter the semiconductor and are detected there. However, simple planar devices suffer from limited detection efficiency which cannot reach more than about 5%. The limit in detection efficiency can be overcome by etching a 3D microstructure of trenches, pores or columns in the detector and filling it with the neutron converter. The overall neutron detection efficiency of such structure with pores was simulated. The results indicate an increase in the detection efficiency by factor of 6 in comparison with a standard planar neutron detector. Samples with different silicon column sizes were fabricated to study the electrical properties of 3D structures. The charge collection efficiency in silicon columns from 10 μm to 800 μm wide and 80 μm high was measured. Single pad detectors with pores were also fabricated and tested for thermal neutron detection. The samples have square pores of 20 μm wide, ~60 μm deep. The pore pitch is 70 μm. 6LiF was used as the neutron converter in all cases. Pulse height spectra of the filled samples irradiated by thermal neutrons were measured. The measurement proved functionality of such detectors and its usability for thermal neutron detection.
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| 8. |
- Apoznański, Grzegorz, et al.
(författare)
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Barbastelles in a Production Landscape : Where Do They Roost?
- 2021
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Ingår i: Acta Chiropterologica. - 1508-1109. ; 23:1, s. 225-232
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Tidskriftsartikel (refereegranskat)abstract
- Extensive areas of old forests have declined all over the temperate regions of Europe mainly due to extensive forestry. This is likely to have negative impact on bats that roost in trees, such as the western barbastelle Barbastella barbastellus. We investigated its selection of summer roosts in a commercially used landscape in southern Sweden. We captured and radio-tracked 14 bats and found 17 occupied roosts. Nine of the roosts, including two used by a maternity colony (ca. 30 females), were located between overlapping boards on the gables of barns. The remaining eight roosts, all used by single individuals, were under lose bark on thin trees (DBH = 0.2-0.35 m). All recorded roosts had entrances pointing downwards, were adjacent to deciduous trees providing protective darkness, and were in areas without artificial lighting. In the barns, the bats avoided the northern aspect, which is the lightest (sun sets in the NW and rises in the NE). Roost temperatures did not differ between tree-and barn roosts. Average ambient light intensity on emergence and return was 13.3 lux (SD = 10.1 lux). Roosts in trees and barns shared common physical characteristics, yet despite this both maternity roosts were located in barns, perhaps because such roosts had more space than available tree roosts. Our results suggest that in areas deprived of large trees and extensive old forest, barbastelle shows flexibility in roost selection, although they consistently avoid artificial lights of all kinds. An abundance of potential roosts in trees and buildings and absence of light pollution are therefore key elements in a holistic conservation program for this species.
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| 11. |
- Frisk, Karin, et al.
(författare)
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Compound materials by PM-HIP
- 2014
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Ingår i: Powder Metallurgy. - 0032-5899 .- 1743-2901. ; 57:5, s. 341-347
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Tidskriftsartikel (refereegranskat)abstract
- There are many applications where compound materials can be of interest, for example when different properties are needed in different parts of a component. Compound materials can be produced by hot isostatic pressing (HIP) of powder metallurgical materials. One aspect that should be considered in the design is the quality of the interface between the two different material compositions. Diffusion during HIP can cause formation of brittle phases in the interface or deteriorate properties by diffusion of alloying elements. The present work shows results from a study where different steel types were joined (quench and temper steel/air hardening steel/bearing steel with a tool steel/corrosion resistant martensitic steel). The evaluation was performed by computational predictions and by small scale HIP experiments that were evaluated by microstructure analysis and chemical analysis. © 2014 Institute of Materials, Minerals and Mining.
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| 12. |
- Gomez, B., et al.
(författare)
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Levels and risk assessment for humans and ecosystems of platinum group elements in the airborne particles of some European cities
- 2002
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Ingår i: The Science of the Total Environment. ; 299, s. 1-19
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Tidskriftsartikel (refereegranskat)abstract
- Traffic is the main source of platinum-group element (PGE) contamination in populated urban areas. There is increasing concern about the hazardous effects of these new pollutants for people and for other living organisms in these areas. Airborne and road dusts, as well as tree bark and grass samples were collected at locations in the European cities of Göteborg (Sweden), Madrid (Spain), Rome (Italy), Munich (Germany), Sheffield and London (UK). Today, in spite of the large number of parameters that can influence the airborne PGE content, the results obtained so far indicate significantly higher PGE levels at traffic sites compared with the rural or non-polluted zones that have been investigated (background levels). The average Pt content in airborne particles found in downtown Madrid, Göteborg and Rome is in the range 7.313.1 pg m−3. The ring roads of these cities have values in the range 4.117.7 pg m−3. In Munich, a lower Pt content was found in airborne particles (4.1 pg m−3). The same tendency has been noted for downtown Rh, with contents in the range 2.22.8 pg m−3, and in the range 0.83.0 and 0.3 pg m−3 for motorway margins in Munich. The combined results obtained using a wide-range airborne classifier (WRAC) collector and a PM-10 or virtual impactor show that Pt is associated with particles for a wide range of diameters. The smaller the particle size, the lower the Pt concentration. However, in particles
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| 13. |
- Hansson, Karin, 1967-, et al.
(författare)
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A Toolbox of Feminist Wonder : Theories and methods that can make a difference
- 2023
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Ingår i: CSCW '23 Companion. - New York : Association for Computing Machinery (ACM). - 9798400701290 ; , s. 476-480
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Konferensbidrag (refereegranskat)abstract
- theoretical and methodological approaches that have provided us with useful tools to see things differently and make space for change. Since its inception over a decade ago, feminist HCI has progressed from the margins to mainstream HCI, with numerous references in the literature. Feminist HCI has also evolved to incorporate other critical HCI practices such as Queer HCI, participatory design, and speculative design. While feminist approaches have grown in popularity and become mainstream, it is getting more difficult to distinguish the feminist emancipatory core from other attempts of developing and improving society in various ways. In this workshop, we therefore want to revisit our feminist roots, where theory is a liberatory and creative practice, motivated by affect, curiosity, and wonder. From this standpoint, we consider which of our feminist tools can make a significant difference today, in a highly datafied world. The goal of this workshop is to; 1) create an inventory of feminist theories and concepts that have had an impact on our work as designers, educators, researchers, and activists; 2) develop a feminist toolbox for the CSCW community to strengthen our feminist literacy.
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| 14. |
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| 15. |
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| 16. |
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| 17. |
- Nilsson, Per, et al.
(författare)
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SCADA data and the quantification of hazardous events for QMRA
- 2007
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Ingår i: Journal of Water and Health. - : IWA Publishing. - 1477-8920 .- 1996-7829. ; 5, s. 99-105
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this study was to assess the use of on-line monitoring to support the QMRA at water treatment plants studied in the EU MicroRisk project. SCADA data were obtained from diary records, grab three Catchment-to-Tap Systems (CTS) along with system descriptions, sample data and deviation reports. Particular attention was paid to estimating hazardous event frequency, duration and magnitude. Using Shewart and CUSUM we identified 'change-points' corresponding to events of between 10 min and > 1 month duration in timeseries data. Our analysis confirmed it is possible to quantify hazardous event durations from turbidity, chlorine residual and pH records and distinguish them from non-hazardous variability in the timeseries dataset. The durations of most 'events' were short-term (0.5-2.3 h). These data were combined with QMRA to estimate pathogen infection risk arising from such events as chlorination failure. its interpretation was While analysis of SCADA data alone could identify events provisionally, severely constrained in the absence of diary records and other system information. SCADA data analysis should only complement traditional water sampling, rather than replace it. More work on on-line data management, quality control and interpretation is needed before it can be used for event characterization routinely for event characterrisation.
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| 18. |
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| 19. |
- Pellerine, Liam P., et al.
(författare)
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Step Length, But Not Stepping Cadence, Strongly Predicts Physical Activity Intensity During Jogging and Running
- 2023
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Ingår i: Measurement in Physical Education and Exercise Science. - : Taylor & Francis. - 1091-367X .- 1532-7841. ; 27:4, s. 352-361
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Tidskriftsartikel (refereegranskat)abstract
- Device-based measures often rely on the positive relationship between walking cadence and metabolic equivalents of task (METs) to estimate physical activity. It is unknown whether this relationship remains during jogging/running. The study purpose was to investigate the relationships between METs, cadence, and step length during walking and jogging/running. A treadmill protocol with 5 walking (3.2–6.4 km•hr−1) and 5 jogging/running stages (8.0–11.3 km•hr−1) was completed in 43 adults (23 ± 5 years, 19♀). Predictors of METs during walking and jogging/running were determined by generalized mixed modeling. The strongest prediction models for walking (R2 = 0.72, P < .001) and jogging/running (R2 = 0.75, P < .001) included cadence2, cadence, step length, age, and leg length (all, P < .001). Step length accounted for 49.1% and 78.3% of model variance during walking and jogging/running, respectively. METs are poorly estimated by cadence during jogging/running but step length reduces error. Strategies to measure step length in free-living settings could better predict physical activity intensity.
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| 20. |
- Petterson, Anders, et al.
(författare)
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A Bernoulli principle gripper for handling of planar and 3D (food) products
- 2010
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Ingår i: Industrial robot. - : Emerald. - 0143-991X .- 1758-5791. ; 37:6, s. 518-526
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Purpose - The purpose of this paper is the increase the flexibility of robots used for handling of 3D (food) objects handling by the development and evaluation of a novel 3D Bernoulli gripper. Design/methodology/approach - A new gripper technology have been designed and evaluated. A deformable surface have been used to enable individual product handling. The lift force generated and the force exerted on the product during gripping is measured using a material tester instrument. Various products are tested with the gripper. A experimental/theoretical approach is used to explain the results. Findings - A deformable surface can be used to generate a lift force using the Bernoulli principle on 3D objects. Using a small forming a significant increase in the lift force generated is recorded. Increasing the forming further was shown to have little or even negative effects. The forces exerted on the product during forming was measured to be sufficiently low to avoid product damage. Research limitations/implications - To be able to improve the grippers lift strength a better model and understanding of the flow is needed. Originality/value - A novel Bernoulli gripper for 3D Bernoulli gripping have been designed and evaluated. The gripper enables flexible and delicate handling of various product shapes, 3D as well as 2D. Increased utilization of robots in the food industry can be gained. © Emerald Group Publishing Limited [ISSN 0143-991X].
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| 21. |
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| 22. |
- Skorodko, T., et al.
(författare)
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Excitation of the Roper resonance in single- and double-pion production in nucleon-nucleon collisions
- 2008
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Ingår i: European Physical Journal A. - : Springer Science and Business Media LLC. - 1434-6001 .- 1434-601X. ; 35:3, s. 317-319
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Tidskriftsartikel (refereegranskat)abstract
- In most investigations the Roper resonance is sensed only very indirectly via complex partial-wave analyses. We find indications for its excitation in the invariant n pi(+) mass spectrum of the pp -> np pi(+) reaction at M approximate to 1360 MeV with a width of approximate to 150 MeV . The values fit very favorably to the most recent phase shift results as well as to the observations at BES. In the near-threshold two-pion production pp -> pp pi(0)pi(0) , where the Roper excitation and its subsequent decays via the routes N* -> Delta pi -> N pi pi and N* -> N sigma are the only dominant processes, we find its direct decay into the N sigma channel to be the by far dominating decay process -in favor of a monopole excitation of the Roper resonance.
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| 23. |
- Skorodko, T., et al.
(författare)
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THE pp -> pp pi(0)pi(0) REACTION AND ITS LIMITING CASE, FUSION TO QUASI-BOUND He-2, IN SEARCH OF THE ABC EFFECT
- 2011
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Ingår i: International Journal of Modern Physics A. - 0217-751X .- 1793-656X. ; 26:3-4, s. 702-704
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Tidskriftsartikel (refereegranskat)abstract
- The pi(0)pi(0) production in pp-collisions has been investigated in exclusive and kinematically complete measurements from threshold up to T-p = 1.4 GeV. For incident energies T-p > 1 GeV, i.e. in the region beyond the Roper excitation, the Delta Delta excitation process takes over. The data are well explained by the t-channel Delta Delta process dominated by pion exchange. There is no low-mass enhancement (ABC effect) in the pi(0)pi(0)-invariant mass distribution beyond that given by the conventional t-channel Delta Delta process. This is also true for the limiting case, where the protons are in the quasi-bound He-2 state.
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| 24. |
- Skovsted, Christian B., et al.
(författare)
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The scleritome of Paterimitra : an Early Cambrian stem group brachiopod from South Australia
- 2009
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Ingår i: Proceedings of the Royal Society of London. Biological Sciences. - : The Royal Society. - 0962-8452 .- 1471-2954. ; 276:1662, s. 1651-1656
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Tidskriftsartikel (refereegranskat)abstract
- Early Cambrian tommotiids are problematic fossil metazoans with external organophosphatic sclerites that have been considered to be basal members of the lophophorate stem group. Tommotiids are almost exclusively known from isolated or rarely fused individual sclerites, which made previous reconstructions of the actual organism highly conjectural. However, the recent discovery of the first articulated specimens of the tommotiid Eccentrotheca revealed a tubular sclerite arrangement (scleritome) that limited the possible life habit to sessile filter feeding and thus further supported a lophophorate affinity. Here, we report the first articulated specimens of a second tommotiid taxon, Paterimitra from the Early Cambrian of the Arrowie Basin, South Australia. Articulated specimens of Paterimitra are composed of two bilaterally symmetrical sclerite types and an unresolved number of small, asymmetrical and irregular crescent-shaped sclerites that attached to the anterior margin of the symmetrical sclerites. Together, the sclerites form an open cone in which the symmetrical sclerites are joined together and form a small posterior opening near the base of the scleritome, while the irregular crescent-shaped sclerites defined a broad anterior opening. The coniform scleritome of Paterimitra is interpreted to have attached to hard substrates via a pedicle that emerged through the small posterior opening ( sometimes forming a tube) and was probably a sessile filter feeder. The scleritome of Paterimitra can be derived from the tubular scleritome of Eccentrotheca by modification of basal sclerites and reduction in tube height, and probably represents a more derived member of the brachiopod stem group with the paired symmetrical sclerites possibly homologous to brachiopod valves.
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| 25. |
- Sokolova, Ekaterina, 1986, et al.
(författare)
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Microbial risk assessment of drinking water based on hydrodynamic modelling of pathogen concentrations in source water
- 2015
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Ingår i: Science of the Total Environment. - : Elsevier BV. - 0048-9697 .- 1879-1026. ; 526, s. 177-186
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Tidskriftsartikel (refereegranskat)abstract
- Norovirus contamination of drinking water sources is an important cause of waterborne disease outbreaks. Knowledge on pathogen concentrations in source water is needed to assess the ability of a drinking water treatment plant (DWTP) to provide safe drinking water. However, pathogen enumeration in source water samples is often not sufficient to describe the source water quality. In this study, the norovirus concentrations were characterised at the contamination source, i.e. in sewage discharges. Then, the transport of norovirus within the water source (the river Gota alv in Sweden) under different loading conditions was simulated using a hydrodynamic model. Based on the estimated concentrations in source water, the required reduction of norovirus at the DWTP was calculated using quantitative microbial risk assessment (QMRA). The required reduction was compared with the estimated treatment performance at the DWTP. The average estimated concentration in source water varied between 4.8 x 10(2) and 7.5 x 10(3) genome equivalents L-1; and the average required reduction by treatment was between 7.6 and 8.8 Log(10). The treatment performance at the DWTP was estimated to be adequate to deal with all tested loading conditions, but was heavily dependent on chlorine disinfection, with the risk of poor reduction by conventional treatment and slow sand filtration. To our knowledge, this is the first article to employ discharge-based QMRA, combined with hydrodynamic modelling, in the context of drinking water. (C) 2015 Elsevier B.V. All rights reserved.
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