1. |
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2. |
- Svanberg, Sune, et al.
(författare)
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Applications of terawatt lasers
- 1994
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Ingår i: LASER SPECTROSCOPY - XITH INTERNATIONAL CONFERENCE. - : AIP. - 1551-7616 .- 0094-243X. - 1563962624 ; :290, s. 264-269
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Konferensbidrag (refereegranskat)
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3. |
- Abramson, N, et al.
(författare)
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Light-in-flight recording. 5: Theory of slowing down the faster-than-light motion of the light shutter
- 1989
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Ingår i: Applied Optics. - 2155-3165. ; 28:4, s. 759-765
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Tidskriftsartikel (refereegranskat)abstract
- Light-in-flight recording by holography uses a picosecond pulse for the reference beam, which like a sheet of light intersects the hologram plate and produces a sensitivity area that with a speed faster than light moves over the plate like a light shutter. If, however, the front of the reference pulse by diffraction in a grating is tilted relative to its direction of motion, the velocity of the light shutter can be slowed down resulting in increased recording time. The practical result using a reflection grating was a true recording that corresponded to a time compression of two to one. To minimize distortions of the recorded pulse shape we studied intersections that are identical for apparent (ellipsoidal) and true (spheroidal) wavefronts.
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4. |
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5. |
- Bargholtz, Chr., et al.
(författare)
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Measurement of the eta -> pi(+)pi(-)e(+)e(-) decay branching ratio
- 2007
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Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 644:5-6, s. 299-303
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Tidskriftsartikel (refereegranskat)abstract
- The reaction pd -> He-3 eta at threshold was used to provide a clean source of eta mesons for decay studies with the WASA detector at CELSIUS. The branching ratio of the decay eta -> pi(+)pi(-)e(+)e(-) is measured to be (4.3 +/- 1.3 +/- 0.4) x 10(-4).
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6. |
- Bargholtz, Chr., et al.
(författare)
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The WASA detector facility at CELSIUS
- 2008
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Ingår i: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 594:3, s. 339-350
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Tidskriftsartikel (refereegranskat)abstract
- The WASA 4 pi multidetector system, aimed at investigating light meson production in light ion collisions and eta meson rare decays at the CELSIUS storage ring in Uppsala is presented. A unique feature of the system is the use of hydrogen pellets as internal targets for the first time. A detailed description of the design, together with the anticipated and achieved performance parameters are given. (C) 2008 Elsevier B.V. All rights reserved.
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7. |
- Bashkanov, M., et al.
(författare)
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Double-Pionic Fusion of Nuclear Systems and the "ABC" Effect : Approaching a Puzzle by Exclusive and Kinematically Complete Measurements
- 2009
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Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 102:5, s. 052301-
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Tidskriftsartikel (refereegranskat)abstract
- The ABC effect-a puzzling low-mass enhancement in the pi pi invariant mass spectrum, first observed by Abashian, Booth, and Crowe-is well known from inclusive measurements of two-pion production in nuclear fusion reactions. Here we report on the first exclusive and kinematically complete measurements of the most basic double-pionic fusion reaction pn -> d pi(0)pi(0) at beam energies of 1.03 and 1.35 GeV. The measurements, which have been carried out at CELSIUS-WASA, reveal the ABC effect to be a (pi pi)(I=L=0) channel phenomenon associated with both a resonancelike energy dependence in the integral cross section and the formation of a Delta Delta system in the intermediate state. A corresponding simple s-channel resonance ansatz provides a surprisingly good description of the data.
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8. |
- Bashkanov, M., et al.
(författare)
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Measurement of the slope parameter for the η → 3π0 decay in the pp → ppη reaction
- 2007
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Ingår i: Physical Review C. Nuclear Physics. - 0556-2813 .- 1089-490X. ; 76:4, s. 048201-
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Tidskriftsartikel (refereegranskat)abstract
- The CELSIUS-WASA setup is used to measure the 3π0 decay of η mesons produced in pp interactions with beam kinetic energies of 1.36 and 1.45 GeV. The efficiency-corrected Dalitz plot and density distributions for this decay are shown, together with a fit of the quadratic slope parameter α yielding α = −0.026 ± 0.010(stat) ± 0.010(syst). This value is compared to recent experimental results and theoretical predictions.
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9. |
- Bejnö, Hampus, et al.
(författare)
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Adapting the Preschool Environment to the Needs of Children on the Autism Spectrum in Sweden : A quasi-experimental study
- 2023
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Ingår i: Scandinavian Journal of Occupational Therapy. - : Informa UK Limited. - 1103-8128 .- 1651-2014. ; 30:3, s. 278-297
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND Children on the autism spectrum may receive Early Intensive Behavioural Intervention (EIBI) in Sweden to support development by providing learning opportunities. However, research suggests a need to improve the quality of their learning environment.AIM This pre-registered study (#NCT03634761) aimed to evaluate the Swedish Autism Program Environment Rating Scale (APERS-P-SE) as a means to promote the quality of the pre-school learning environment for children on the autism spectrum, along with outcomes for these children, and their pre-school staff.MATERIAL AND METHODS In a quasi-experimental study, pre-school staff (n = 35) conducted either EIBI supported by in-service training and on-site coaching based on APERS-P-SE assessment (at k = 9 preschools) or EIBI only (k = 8), during an 8-months period.RESULTS The quality of the immediate learning environment (primary outcome) increased significantly in the EIBI/APERS-P-SE preschools. However, changes in child and pre-school staff measures were not significant.CONCLUSIONS AND SIGNIFICANCE In-service training and on-site coaching based on APERS-P-SE assessments can increase the quality of the learning environment in Swedish pre-school. Studies of longer duration and larger sample size are required to determine if using the APERS-P-SE can also achieve desired behavioural change for children-, and impact pre-school staff applying EIBI.
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10. |
- Bejnö, Hampus, et al.
(författare)
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Cross-Cultural Content Validity of the Autism Program Environment Rating Scale in Sweden
- 2019
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Ingår i: Journal of autism and developmental disorders. - : Springer Science and Business Media LLC. - 0162-3257 .- 1573-3432. ; 49:5, s. 1853-1862
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Tidskriftsartikel (refereegranskat)abstract
- Increasing rates of autism spectrum disorder (ASD) and younger age at diagnosis pose a challenge to preschool intervention systems. In Sweden, most young autistic children receive intervention service in community-based preschool programs, but no tool is yet available to assess the quality of the preschool learning environment. This study adapted the Autism Program Environment Rating Scale Preschool/Elementary to Swedish community context (APERS-P-SE). Following translation and a multistep modification process, independent experts rated the content validity of the adaptation. Findings indicate high cross-cultural validity of the adapted APERS-P-SE. The cultural adaption process of the APERS-P-SE highlights similarities and differences between the American and Swedish preschool systems and their impact on early ASD intervention.
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11. |
- Bejnö, Hampus, 1984-
(författare)
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Early intervention and autism : Improving preschool program quality for children with autism spectrum disorder receiving Early Intensive Behavioral Intervention using the Autism Program Environment Rating Scale (APERS)
- 2021
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The quality of the learning environment in preschool is of significant importance for children with autism spectrum disorder (ASD). However, very limited research has addressed how this environment can be improved. In regard to early intervention, most previous studies have primarily focused on child characteristics, and intervention content and quantity, rather than the broader learning environment in which interventions are delivered. Thus, the overall aim of this thesis was to study the quality of the learning environment for children with ASD. In particular, the focus was on children who receive Early Intensive Behavioral Intervention (EIBI) in community-based Swedish preschools, using the Autism Program Environment Rating Scale (APERS). Within this framework, three studies were conducted.In study 1, we translated, culturally adapted, and systematically assessed the content validity of APERS, a rating scale designed to assess the program quality for children with ASD in educational settings. In the process, the scale was modified to make the instrument as relevant as possible for the Swedish preschool context, and re-named APERS-P-SE. Nine experts rated the clarity and comprehensiveness of the individual items, as well as the relevance of the scale in its entirety. In study 2, we evaluated APERS-P-SE as the foundation for professional development for preschool staff working with children with ASD receiving EIBI, to promote preschool learning environment quality (primary outcome), and outcomes for autistic children, and preschool staff (secondary outcomes). Using a quasi-experimental design, preschool staff either implemented EIBI enriched by in-service training and on-site coaching based on APERS-P-SE assessments (k = 9), or EIBI only (k = 8) during 8 months. A total of 17 children and 35 preschool staff participated, across 17 preschools. In study 3, individual interviews and focus-group interviews were conducted with preschool staff, preschool principals, habilitation supervisors, and parents to children with ASD who had participated in study 2 and received the APERS-P-SE-based intervention. Through these interviews, the different groups of stakeholders provided their thoughts about what they found to be the most important aspects of preschool programs for autistic children who receive EIBI, and their opinions and experiences of participating in study 2. Study 1 demonstrated a high level of content validity for the Swedish version of the APERS. In study 2, the EIBI/APERS-P-SE preschools significantly improved their learning environment, compared to the preschools that received EIBI only. Outcomes for autistic children and preschool staff did not differ significantly between the groups, despite positive descriptive findings. In study 3, four themes were identified as being key aspects of preschool programs with high quality to promote optimal development of children with ASD: (1) staff’s competence, (2) children’s inclusion and participation, (3) collaboration, and (4) learning environment. Overall, the stakeholders described the APERS-P-SE-based model as helpful in improving children’s participation, preschool staff’s engagement with the child, and optimizing child outcomes.Taken together, the results indicate that APERS-P-SE is an instrument with a high level of content validity, and that it can be used in combination with in-service training and on-site coaching to improve preschool program quality for children with ASD.
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12. |
- Bejnö, Hampus, et al.
(författare)
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From Someone Who May Cause Trouble to Someone You Can Play With : Stakeholders' Perspectives on Preschool Program Quality for Autistic Children
- 2022
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Ingår i: Journal of autism and developmental disorders. - : Springer Science and Business Media LLC. - 0162-3257 .- 1573-3432. ; 52:9, s. 3890-3908
-
Tidskriftsartikel (refereegranskat)abstract
- In Sweden, young autistic children typically attend community-based preschool programs, which may not be adapted to their needs. In the current study, stakeholders to autistic children receiving Early Intensive Behavioral Intervention were interviewed following a quasi-randomized study (#NCT03634761) aimed at improving the preschool program quality using the Swedish version of the Autism Program Environment Rating Scale (APERS). Stakeholders provided their perceptions and experiences concerning key factors for high quality preschool programs as well as well as their experiences of the abovementioned APERS study. Applying thematic analysis, stakeholder groups differed in what they emphasized, but all highlighted staff’s competence, children’s inclusion and participation, collaboration, and the learning environment as key program areas that had been positively influenced by the APERS-based intervention.
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13. |
- Bejnö, Hampus, et al.
(författare)
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Using a competency based model to improve prerequisites for implementation of EIBI : Insights and perspectives from Sweden
- 2019
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- A prerequisite for effective implementation of early intensive behavioral interventions is a high quality learning environment. However, research to date suggests that the learning environment in community based Swedish preschools is not optimal for children with ASD. A brief overview of the Swedish early intervention support system will be followed by a description of the cultural adaption of the Autism Program Environment Rating Scale (APERS-PE). Furthermore, an ongoing comparative study involving 17 preschools will be described. All participating preschools have children enrolled in EIBI preschool programs, entailing that paraprofessionals and parents obtain supervision at habilitation centers. In addition preschool staff in the study’s experimental group receive monthly on-site coaching, and in-service training on evidence based practices and autism. Outcome measures include pre-post APERS-PE assessments, child engagement and adaptive behavior, and staff knowledge and self-efficacy. Preliminary findings indicate increased learning environment quality in the study’s experimental group as rated by APERS-PE.
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14. |
- Belitsky, Victor, 1955, et al.
(författare)
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A new 3 mm band receiver for the Onsala 20 m antenna
- 2015
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 580
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Tidskriftsartikel (refereegranskat)abstract
- A new receiver for the Onsala 20 m antenna with the possibility of being equipped with 3 mm and 4 mm bands has been built and the 3 mm channel has been commissioned during the Spring 2014. For single-dish operation, the receiver uses an innovative on-source/off-source optical switch. In combination with additional optical components and within the same optical layout, the switch provides two calibration loads (for the 3 mm and 4 mm channels), sideband rejection measurement, and tuning possibilities. The optical layout of the receiver employs all cold (4 K) offset elliptical mirrors for both channels, whereas the on-off switch employs flat mirrors only. The 3 mm channel employs a sideband separation (2SB) dual polarization receiver with orthomode transducer (OMT), 4-8 GHz intermediate frequency (IF), x? 2pol x? upper and lower sidebands (USB? +? LSB). The cryostat has four optical windows made of high density polyethylene (HDPE) with anti-reflection corrugations, two for the signal and two for each frequency band cold load. The cryostat uses a two-stage cryocooler produced by Sumitomo HI? RDK? 408D2 with anti-vibration suspension of the cold-head to minimize impact of the vibrations on the receiver stability. The local oscillator (LO) system is based on a Gunn oscillator with aphase lock loop (PLL) and four mechanical tuners for broadband operation, providing independently tunable LO power for each polarization. This paper provides a technical description of the receiver and its technology and could be useful for instrumentation engineers and observers using the Onsala 20 m telescope.
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15. |
- Berlowski, M., et al.
(författare)
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Measurement of eta meson decays into lepton-antilepton pairs
- 2008
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Ingår i: Physical Review D. Particles and fields. - : American Physical Society. - 0556-2821 .- 1089-4918. ; 77:3, s. 032004-
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Tidskriftsartikel (refereegranskat)abstract
- A search for rare lepton decays of the eta meson was performed using the WASA detector at CELSIUS. Two candidates for double Dalitz decay eta -> e(+)e(-)e(+)e(-) events are reported with a background of 1.3 +/- 0.2 events. This allows to set an upper limit to the branching ratio of 9.7x10(-5) (90% CL). The branching ratio for the decay eta -> e(+)e(-)gamma is determined to (7.8 +/- 0.5(stat)+/- 0.8(syst))x10(-3) in agreement with world average value. An upper limit (90% CL) for the branching ratio for the eta -> e(+)e(-) decay is 2.7x10(-5) and a limit for the sum of the eta ->mu(+)mu(-)mu(+)mu(-) and eta ->pi(+)pi(-)mu(+)mu(-) decays is 3.6x10(-4).
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16. |
- Berrocal, Edouard, et al.
(författare)
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High-contrast imaging through scattering media using structured illumination and Fourier filtering
- 2016
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Ingår i: Optics Letters. - 0146-9592. ; 41:23, s. 5612-5615
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Tidskriftsartikel (refereegranskat)abstract
- We show in this Letter a novel approach for high-contrast imaging through scattering media by combining structured illumination and Fourier filtering (SIF). To assess the image contrast enhancement at different image spatial frequencies, the modulation transfer function is calculated for four detection schemes: (1) no filtering, (2) Fourier filtering, (3) structured illumination, and (4) SIF filtering. A scattering solution consisting of D = 7.3 μm polystyrene spheres immersed in distilled water and illuminated at λ = 671 nm is used here. We demonstrate the possibility of obtaining, with SIF, an image contrast up to 60% at an optical depth of OD = 10, improving the contrast by a factor of 40 over conventional transmission imaging.
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17. |
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18. |
- Braniste, Viorica, et al.
(författare)
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The gut microbiota influences blood-brain barrier permeability in mice
- 2014
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Ingår i: Science Translational Medicine. - : American Association for the Advancement of Science. - 1946-6234 .- 1946-6242. ; 6:263, s. 263ra158-
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Tidskriftsartikel (refereegranskat)abstract
- Pivotal to brain development and function is an intact blood-brain barrier (BBB), which acts as a gatekeeper to control the passage and exchange of molecules and nutrients between the circulatory system and the brain parenchyma. The BBB also ensures homeostasis of the central nervous system (CNS). We report that germ-free mice, beginning with intrauterine life, displayed increased BBB permeability compared to pathogen-free mice with a normal gut flora. The increased BBB permeability was maintained in germ-free mice after birth and during adulthood and was associated with reduced expression of the tight junction proteins occludin and claudin-5, which are known to regulate barrier function in endothelial tissues. Exposure of germ-free adult mice to a pathogen-free gut microbiota decreased BBB permeability and up-regulated the expression of tight junction proteins. Our results suggest that gut microbiota-BBB communication is initiated during gestation and propagated throughout life.
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19. |
- Breidegard, Björn, et al.
(författare)
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Raytracing in the compensation of the peripheral optics of the eye
- 2000
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Ingår i: Historielärarnas Förenings Årsskrift. - 0439-2434.
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Tidskriftsartikel (refereegranskat)abstract
- Abstract Background: Many people with a visual impairment have only peripheral vision. However, there is limited knowledge of the peripheral optics of the eye and only some measurements are available in this field. Methods: We simulated the paths of peripheral rays through the eye by means of raytracing. Five programs were compared. The OSLO raytracing software proved to be not only the best one in these circumstances but we also found it very well suited to our purpose. Remaining uncertainties are entirely due to a lack of input data about the peripheral part of the optical system of the eye. We designed compensatory optics on the basis of the test results. Results: Lenses have been manufactured in accordance with the calculations made by the program for angles of incidence of 20, 40, and 60 degrees. The lenses are high compensation astigmatic lenses. The results of perimeter examinations of changes in peripheral vision using attachment optics were inconclusive, while tests of the lenses as attachments in front of a fundus camera produced successful preliminary results. Conclusion: The next step is to test peripheral vision compensatory optics in traffic situations (driving simulator). At the same time attempts are being made to find methods and instruments for measuring the peripheral optics of the eye. Keywords: astigmatism, central scotoma, raytracing, macula degeneration, peripheral vision.
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20. |
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21. |
- Bäck-Pettersson, Siv, 1946, et al.
(författare)
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FOU-kompetensförsörjningsprogram för sjuksköterskor i Fyrbodal
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Sammanfattning Betydelsen av FoU-kompetensförsörjningsprogrammet som varit en medveten och strategisk satsning inom FoU-området kan sammanfattas på följande sätt: Deltagarnas behållning och föreskriven akademisk utveckling har haft en närmast hundraprocentig måluppfyllelse och gett kliniskt verksamma sjuksköterskor en bra start på sin akademiska karriär. Programmet illustrerar ett effektivt sätt att stimulera sjuksköterskors livslånga lärande genom att bygga upp förmågan att genomföra och tillämpa omvårdnadsforskning i klinisk praktik. Programmet har också bidragit till utvecklingen av kompetenta handledare för studenter under utbildning. Flertalet av deltagarna har utvecklat både en önskan om och kompetens för att ta på sig ledande uppdrag såväl inom den egna verksamheten som i gränsöverskridande projekt både inom Fyrbodal och nationellt. Programmet har medverkat till att bryta revirtänkande och kan bidra till en mer öppen och gränsöverskridande kultur inom Fyrbodalområdets hälso- och sjukvård. Det har även medverkat till att deltagarna skaffat sig en helhetssyn på och förståelse för olika vårdverksamheter. Programmets design kan användas för att utveckla såväl professionell som vetenskaplig kompetens och kan med fördel användas inom andra yrkesgrupper med medellång vårdutbildning, eller för en tvärprofessionell grupp.
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22. |
- Bäck-Pettersson, Siv, 1946, et al.
(författare)
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Nurses´Experiences of participation in a research and development programme
- 2013
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Ingår i: Journal of Clinical Nursing. - : Wiley. - 0962-1067 .- 1365-2702. ; 22:7-8, s. 1103-1111
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Tidskriftsartikel (refereegranskat)abstract
- Aims and objectives. To describe clinical nurses’ experience of participating in a Research and Development (R&D) programme and its influence on their research interest and ability to conduct and apply nursing research. Background. To stimulate nurses’ research interest and to overcome barriers for building research capacity in nursing, there is a need for sustainable research programmes. A two-year programme was designed for nurses, to take part in both an academic education for master and research seminars and workshops to conduct a research project from idea to publication. Design. A qualitative approach using using focus group interviews. Methods. Registered nurses (n = 12) with a bachelor’s degree in nursing, participated. Data were collected in focus group interviews, after one year and when the programme ended. Content analysis was used to analyse the data. Results. The findings consist of two themes: being a traveller in the world of nursing research, which included three categories, and experiencing professional growth as a result of nursing research training, in both cases focusing on the experience of students involved in a cohesive programme which included four categories: discovering new dimensions of clinical nursing practice; selected and confirmed; supported by professional others; development of professional self-concept. Conclusions. To support early career researchers, there is a need for strong leadership, an organisational and supportive infrastructure underpinning research capability building in nurses. In this context, research strategies, programmes and collaboration between leaders of academia and clinical institutions appear to be essential. Relevance to clinical practice. The R&D programme illustrates an effective way of stimulating nurses’ lifelong learning by building the capacity to conduct and apply nursing research in clinical practice. The structure of the programme can be used as a model in other contexts.
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25. |
- Carlsson, Richard, et al.
(författare)
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Core Erlang 1.0 language specification
- 2000
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- We describe a core language for the concurrent functional language Erlang, aptly named “Core Erlang”, presenting its grammar and informal static and dynamic semantics relative to Erlang. We also discuss built-in functions and other open issues, and sketch a syntax tree representation.
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26. |
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27. |
- Evengård, B, et al.
(författare)
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Low incidence of toxoplasma infection during pregnancy and in newborn in Sweden
- 2001
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Ingår i: Epidemiology and Infection. - 0950-2688. ; 127:1, s. 121-127
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Tidskriftsartikel (refereegranskat)abstract
- To estimate the burden of disease due to congenital toxoplasmosis in Sweden the incidence of primary infections during pregnancy and birth prevalence of congenital toxoplasmosis in 40978 children born in two regions in Sweden was determined. Women possibly infected during pregnancy were identi®ed based on: 1, detection of speci®c IgG based on neonatal screening of the phenylketonuria (PKU) card blood spot followed by retrospective testing of stored prenatal samples to detect women who acquired infection during pregnancy and follow up of their children to 12 months; 2, detection of speci®c IgM on the PKU blood spot. The birth prevalence of congenital toxoplasmosis was 0±73}10000 (95% CI 0±15±2±14) (3}40978). The incidence of primary infection during pregnancy was 5±1}10000 (95% CI 2±6±8±9) susceptible pregnant women. The seroprevalence in the southern part was 25±7% and in the Stockholm area 14±0%. The incidence of infection during pregnancy was low, as the birth prevalence of congenital toxoplasmosis. Neonatal screening warrants consideration in view of the low cost and feasibility.
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28. |
- Falck-Ytter, Terje, et al.
(författare)
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Difficulties maintaining prolonged fixation and attention-deficit/hyperactivity symptoms share genetic influences in childhood
- 2020
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Ingår i: Psychiatry Research. - : Elsevier. - 0165-1781 .- 1872-7123. ; 293
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Tidskriftsartikel (refereegranskat)abstract
- This study investigated the association between the ability to maintain prolonged (2-minute) fixation on a visual target and ADHD traits in a sample consisting of 120 monozygotic and 120 dizygotic twin pairs, aged 9 to 14 years. More intrusive saccades during the task was associated with higher level of parent-reported ADHD traits. Both intrusive saccades and ADHD symptoms had high heritability estimates, and there was a moderate genetic correlation between number of intrusive saccades and ADHD. This study suggests that inability to maintain ocular fixation for longer times is etiologically linked to ADHD traits in the general population.
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29. |
- Fernström, Erik
(författare)
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Fjällmarsch Trantre
- 1979
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Annan publikation (populärvet., debatt m.m.)abstract
- Under vintern 1978 genomfördes Fjällmarsch TranTre på skidor av de sex unga män som har skrivit denna dokumentation av skidturen. Den startade den 1 mars i Transtrand och fortsatte längs den svenska fjällkedjan upp till Treriksröset. Därefter färdades de söderut till tågstationen Torne träsk, som de kom till den 27 april. De hade då tillryggalagt en sträcka på 1500 km under 50 dagar.Texterna handlar om deltagarna, deras förberedelser, färdvägen, dagsetapperna, utrustningen, packningen, maten, lägerplatserna, fotvården, skidorna, vädret, solen, kylan, sömnen, samt djuren och naturen. Det fysiska arbetet studerades vetenskapligt och gav upphov till fyra publikationer som anges nedan som olika poster i DiVA:Schantz, Peter et al. 1982. Training-induced increase in myofibrillar ATPase intermediate fibers in human skeletal muscle. Muscle & Nerve 5:628-636.Schantz, Peter et al. 1983. Adaptation of human skeletal muscle to endurance training of long duration. Clin. Physiol 3:141-151.Schantz, Peter. 1986. Plasticity of human skeletal muscle - with special reference to effectsof physical training on enzyme levels of the NADH shuttles and phenotypicexpression of slow and fast isoforms of myofibrillar proteins, Acta Physiol Scand, vol 128, Suppl.558, pp 1-64. Schantz, Peter. 1980. Långtur - om 150 turåkning längs den svenska fjällkedjan. Stockholm: Trygg-Hansa.
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32. |
- Furebring, Christina, et al.
(författare)
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Evaluation of novel control elements by construction of eukaryotic expression vectors
- 1997
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Ingår i: Gene. - 0378-1119. ; 188:2, s. 191-198
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Tidskriftsartikel (refereegranskat)abstract
- A novel mammalian eukaryotic expression vector for the production of immunoglobulin heavy chain (IgH) genes has been designed. This expression vector contains the variable heavy chain (VH) promoter, the IgH intron enhancer (μE) and the IgH 3' enhancer (3'E). This construct, designated pTIF-1, was stably transfected into the myeloma cell line J558L. A fivefold increase in the expression level of a rearranged IgH gene was observed when using the pTIF-1 vector containing the 3'E compared to an expression vector lacking this enhancer. Interestingly, this positive effect on the expression level of the 3' enhancer appears to be position independent. The introduction of two recently identified Ig control elements, HS3 and HS4, to the vector cassette did not further elevate the expression level in the cell line tested. The pTIF-1 vector can be used for expression of any antibody specificity, using PCR amplification of the VDJ region of interest. Furthermore, the constant region can easily be exchanged, which further facilitates studies to dissect different effector functions of IgH constant genes.
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33. |
- Genoud, Guillaume, et al.
(författare)
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XUV digital in-line holography using high-order harmonics
- 2008
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Ingår i: Applied Physics B. - : Springer Science and Business Media LLC. - 0946-2171 .- 1432-0649. ; 90:3-4, s. 533-538
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Tidskriftsartikel (refereegranskat)abstract
- Abstract in Undetermined A step towards a successful implementation of time-resolved digital in-line holography with extreme ultraviolet (XUV) radiation is presented. Ultra-short XUV pulses are produced as high-order harmonics of a femtosecond laser and a Schwarzschild objective is used to focus harmonic radiation at 38 nm and to produce a strongly divergent reference beam for holographic recording. Experimental holograms of thin wires are recorded and the objects reconstructed. Descriptions of the simulation and reconstruction theory and algorithms are also given. Spatial resolution of a few hundreds of nanometers is potentially achievable, and the micrometer resolution range is demonstrated.
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34. |
- Golman, Klaes, et al.
(författare)
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13C-angiography.
- 2002
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Ingår i: Academic Radiology. - 1878-4046. ; 9:Suppl 2, s. 507-510
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Tidskriftsartikel (refereegranskat)
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35. |
- Gustafsson, Mats, et al.
(författare)
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High-resolution digital transmission microscopy: a Fourier holography approach
- 2004
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Ingår i: Optics and Lasers in Engineering. - 0143-8166. ; 41:3, s. 553-563
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Tidskriftsartikel (refereegranskat)abstract
- A spherical reference field is used to construct a digital holographic system with a demonstrated resolution up to 228 line pairs per mm. The reference field originates from a GRIN lens placed 1 mm from the illuminated object. This allows the use of a standard sensor to record the hologram with the required numerical aperture. The image is determined by evaluation of the Rayleigh–Sommerfeld diffraction integral that relates the object field in the image plane to the object field in the sensor plane. Experimental results are given for two charge coupled device sensors and one complementary metal-oxide-semiconductor active pixel sensor.
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36. |
- Gustafsson, Mats, et al.
(författare)
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High resolution digital transmission microscopy : a Fourier holography approach
- 2002
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- A spherical reference field is used to construct a digital holography system with a demonstrated resolution down to 228 line pairs per mm. The reference field origin from a GRIN lens placed 1mm from the illuminated object. This allows the use of a standard sensor to record the hologram with the required numerical aperture. The image is determined by evaluation of the Rayleigh-Sommerfeld diffraction integral that relates the object field in the image plane to the object field in the sensor plane. Experimental results are given for two charge couple device sensors and one complementary metaloxide- semiconductor active pixel sensor.
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37. |
- Hampus, Bejnö, et al.
(författare)
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Cross-Cultural Content Validity of the Autism Program Environment Rating Scale in Sweden
- 2019
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Ingår i: 12th Autism-Europe International Congress – September 13-15th 2019. ; , s. 94-95
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Introduction: Increased diagnoses rates of autism and earlier identification pose new challenges to preschools and services delivering early intervention to children on the spectrum. A prerequisite for successful implementation of support is a high quality preschool learning environment. Here, we briefly describe the process of translating, culturally adapting and validating the contents of the Autism Program Environment Rating scale (APERS), originally designed for assessing the quality of the learning environment for children and adolescents with autism in the USA, to a European language and educational context.Methods: In an authorized step-wise procedure, the 59 item scale was translated by a PhD level clinician fluent in English with expertise in autism and psychometrics. Subsequently, following internal feedback from the research team, adaptions addressing translation and cultural adaption of the scale were made. Then, five Swedish external preschool and early intervention experts were invited to provide feedback on the cultural appropriateness of the adapted scale. Lastly, nine additional independent external experts within the field of autism, preschool and early intervention were invited to rate the content validity of the adapted scale. Relevance of subdomains and domains was assessed as well as clarity and comprehensiveness for all of the scale’s items. Experts also rated the practical relevance, need, usefulness, and feasibility of the scale as a whole, and provided anecdotal formative feedback.Results: All items, subdomains, and domains of the scale were estimated by the raters as showing sufficient content validity (Content validity index ≥,.79). Several Swedish experts highlighted the need for such a scale, and the usefulness of the scale as a means to assess and then support preschool staff to improve learning environment for children with autism. However, some concerns were raised about the comprehensiveness of the scale and the challenges preschools will meet in improving their learning environment. Discussion There seems to be a need for a rating scale to assess and improve the learning environment for children with autism in preschool settings. Although the usefulness and content validity of the translated and adapted scale was established, little is still known about other psychometric properties of the scale, and more work needs to be done to assess its usefulness as a tool for systematic improvement of preschool program quality.
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38. |
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39. |
- Hellqvist, Sven, et al.
(författare)
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Vinbärsgallkvalster
- 2009
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Ingår i: Faktablad om växtskydd. Trädgård. - 0281-8566.
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Annan publikation (populärvet., debatt m.m.)abstract
- Vinbärsgallkvalstret ( Cecidophyopsis ribis) angriper svarta vinbär. Detta gallkvalster förekommer över hela landet och är det allvarligaste skadedjuret på odlade svarta vinbär. Angrepp av gallkvalster kan reducera skörden dels genom kvalstrens egna skador, dels genom att de sprider en virussjukdom som medför att buskarna blir sterila. Ä ven röda vinbär kan angripas av gallkvalster. Det handlar om ett ett närbesläktat gallkvalster, C. selachodon. Endast några enstaka fall har hittills rapporterats från Sverige.
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40. |
- Hellroth, Sven, 1956-
(författare)
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Från arbetsstatistik till konjunkturöversikt : arbetarfrågan och etablerandet av en statlig konjunkturbevakning i Sverige 1893-1914
- 2011
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis investigates the emergence and establishment of an early public monitoring system of the Swedish economy prior to the First World War. The study relies on a careful examination of the source materials with the view to map why and how the monitoring of the Swedish economy emerged, who demanded it, how the public supervision of the economy was organised and administrated and the results of the efforts. The common driving force was an increasing political interest in Sweden and elsewhere over the labour issue towards the end of the nineteenth century. In fact, the establishment of the monitoring system of the Swedish economy was largely the result of a broader international statistical respons to the labour question by the end of that century. The emergence of a public monitoring of the economy was driven by a general need for measuring the effect of industrialisation on the labour market, especially the growing problems with episodes of involuntary unemployment in the industrialised countries towards the end of the century.The thesis is divided in two parts with a total of ten chapters. It is written within a traditional narrative structure, that is, the beginning, the middle and the end. The first part examines the emergence of the surveillance of the labour market and consists of three chapters according to the narrative structure covering the period 1893-1913. The second part consists of three chapters that investigate the establishment of a monthly economic survey of the Swedish economy between 1910 and 1914, structured in the same way as the part one. The establishment of this early public monitoring of the Swedish economy should be regarded as a forerunner of the National Institute of Economic Research (Konjunkturinstitutet) 1937.
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41. |
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42. |
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43. |
- Hiukka, A, et al.
(författare)
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ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase and Increased binding to Biglycan.
- 2009
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Ingår i: Diabetes. - : American Diabetes Association. - 1939-327X .- 0012-1797. ; 58:9, s. 2018-2026
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Tidskriftsartikel (refereegranskat)abstract
- Objective- Apolipoprotein CIII (apoCIII) is an independent risk factor for cardiovascular disease, but the molecular mechanisms involved are poorly understood. Here, we investigated potential proatherogenic properties of apoCIII-containing LDL from hypertriglyceridemic patients with type 2 diabetes. Research design and methods - LDL was isolated from controls and subjects with type 2 diabetes, and from apoB transgenic mice. LDL-biglycan binding was analyzed with a solid-phase assay using immunoplates coated with biglycan. Lipid composition was analyzed with mass spectrometry. Hydrolysis of LDL by sphingomyelinase was analyzed after labeling plasma LDL with [(3)H]sphingomyelin. ApoCIII isoforms were quantified after isoelectric focusing. Human aortic endothelial cells were incubated with desialylated apoCIII or with LDL enriched with specific apoCIII isoforms. Results- We showed that enriching LDL with apoCIII only induced a small increase in LDL-proteoglycan binding, and this effect was dependent on a functional Site A in apoB100. Our findings indicated that intrinsic characteristics of the diabetic LDL other than apoCIII per se are responsible for further increased proteoglycan binding of diabetic LDL with high endogenous apoCIII, and we showed alterations in the lipid composition of diabetic LDL with high apoCIII. We also demonstrated that high apoCIII increased susceptibility of LDL to hydrolysis and aggregation by SMase. In addition, we demonstrated that sialylation of apoCIII increased with increasing apoCIII content, and that sialylation of apoCIII was essential for its proinflammatory properties. Conclusions- We have demonstrated a number of features of apoCIII-containing LDL from hypertriglyceridemic patients with type 2 diabetes that could explain the proatherogenic role of apoCIII.
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44. |
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45. |
- Holmstedt, Göran, et al.
(författare)
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University training of senior fire brigade officers. The new approach in Sweden
- 1989
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Ingår i: Fire Safety Journal. - : Elsevier BV. - 0379-7112. ; 15:1, s. 95-101
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Tidskriftsartikel (refereegranskat)abstract
- In Sweden a fundamental development has recently taken place in the training of future senior fire brigade officers. There are two main changes: the training period has been substantially increased and the theoretical part upgraded to university curriculum level with final requirements corresponding to a university undergraduate degree. The new educational system reflects the changing and expanding role of fire brigades and the need for a professionally improved leadership. To put the new training system into a proper context, the varied and dissimilar responsibilities of a Swedish fire brigade officer should be touched upon. Four main sectors are identified: business administration, fire prevention, training of employed staff and rescue service operations. The main structure of the training system and the university curriculum are discussed.
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46. |
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47. |
- Isaksson, Johan, et al.
(författare)
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Brief Report : Association Between Autism Spectrum Disorder, Gastrointestinal Problems and Perinatal Risk Factors Within Sibling Pairs.
- 2017
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Ingår i: Journal of autism and developmental disorders. - : Springer Science and Business Media LLC. - 0162-3257 .- 1573-3432. ; 47:8, s. 2621-2627
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Tidskriftsartikel (refereegranskat)abstract
- Autism spectrum disorder (ASD) has been associated with gastrointestinal (GI) problems, but the nature of this association is unclear. Parents to siblings, concordant or discordant for ASD (N = 217), participated in a web survey covering mother's weight gain during pregnancy, maternal viral/bacterial infection and use of antibiotics, duration of breastfeeding, mode of delivery, birth weight and child GI problems. ASD was associated with GI problems and perinatal environmental risk, based on a summation of maternal infection and antibiotic use during pregnancy and/or the breastfeeding period. The association between GI problems and ASD remained within the sibling pairs (β = 1.23; p < .001) in the adjusted model. Our results indicate non-shared environmental effects on the ASD/GI association, but none of the factors examined explained the link.
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48. |
- Joelsson, Tove, et al.
(författare)
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High strength paper from high yield pulps by means of hot-pressing
- 2020
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Ingår i: Nordic Pulp & Paper Research Journal. - : De Gruyter Open Ltd. - 0283-2631 .- 2000-0669. ; 35:2, s. 195-204
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Tidskriftsartikel (refereegranskat)abstract
- The hypothesis is that it should be possible to modify papermaking conditions in line with the softening properties of high yield pulp fibres and achieve similar strength properties to conventional chemical pulp based paper. We therefore investigated the rheological and physical properties of high yield pulp based papers during hot-pressing. Our results confirm that increased temperature combined with sufficient pressure enables permanent densification by softening of lignin, producing very high tensile strength. This treatment also significantly improved the wet tensile strength in comparison to bleached kraft pulp without using wet strength agents. The high yield pulps used here were spruce based thermomechanical pulp, chemi-thermomechanical pulp, and high temperature chemi-thermomechanical pulp, and birch-aspen based neutral sulphite semi chemical pulp, with spruce-pine based bleached kraft pulp as reference. Rapid Köhten sheets of 150 g/m 2 150\hspace{0.1667em}\text{g}/{\text{m}^{2}} and 50 % dryness were hot-pressed in a cylinder-press at 20-200 °C, 7 MPa, and 1 m/min. The mechanical properties showed great improvements in these high yield pulp papers, with tensile index increased to 75 kNm/kg and compression strength index to 45 kNm/kg; levels close to and better than bleached kraft. Wet strength increased to 16 Nm/g compared to 5 Nm/g for bleached kraft.
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49. |
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50. |
- Joelsson, Tove, et al.
(författare)
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Improving paper wet-strength by means hot-pressing and increased lignin content in pulp fibers
- 2019
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Ingår i: Paper Conference and Trade Show, PaperCon 2019. - : TAPPI Press. - 9781510893948 ; , s. 704-713
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Konferensbidrag (refereegranskat)abstract
- The research presented here show ways to improve wet strength by means of hot-pressing without strength additives when using lignin containing pulps as unbleached softwood chemical pulps (NSK) and lignin rich softwood chemithermomechanical pulps (CTMP). NSK (Northern Softwood kraft) laboratory scale produced pulps of 3 different levels of natural lignin (or kappa number) and two commercial pulps, NBSK (Northern Bleached Softwood kraft) and CTMP, were compared evaluating dry- and wet-strength properties. Staining methods and light microscope were used to study cross sections of paper sheets. The CTMP fibers collapse to an increasing degree with pressing temperature whereas NBSK/NSK do not change. The microscopy methods show the distribution of lignin within the paper structure. Sheets made from NSK show a significant increase in wet strength from 4kNm/kg to 23kNm/kg, when increasing temperature from 20°C to 200°C. CTMP show corresponding increase from 2kNm/kg to 16kNm/kg. No increase in dry strength or in density can be observed in case of NBSK/NSK, while the CTMP show an increase of 53% and 100% respectively. The SCT values show an increase up to 35% for lignin-rich NSK based paper sheets when hot-pressing.
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