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1.
  • Tinetti, Giovanna, et al. (författare)
  • The EChO science case
  • 2015
  • Ingår i: Experimental astronomy. - : Springer Science and Business Media LLC. - 0922-6435 .- 1572-9508. ; 40:2-3, s. 329-391
  • Tidskriftsartikel (refereegranskat)abstract
    • The discovery of almost two thousand exoplanets has revealed an unexpectedly diverse planet population. We see gas giants in few-day orbits, whole multi-planet systems within the orbit of Mercury, and new populations of planets with masses between that of the Earth and Neptune-all unknown in the Solar System. Observations to date have shown that our Solar System is certainly not representative of the general population of planets in our Milky Way. The key science questions that urgently need addressing are therefore: What are exoplanets made of? Why are planets as they are? How do planetary systems work and what causes the exceptional diversity observed as compared to the Solar System? The EChO (Exoplanet Characterisation Observatory) space mission was conceived to take up the challenge to explain this diversity in terms of formation, evolution, internal structure and planet and atmospheric composition. This requires in-depth spectroscopic knowledge of the atmospheres of a large and well-defined planet sample for which precise physical, chemical and dynamical information can be obtained. In order to fulfil this ambitious scientific program, EChO was designed as a dedicated survey mission for transit and eclipse spectroscopy capable of observing a large, diverse and well-defined planet sample within its 4-year mission lifetime. The transit and eclipse spectroscopy method, whereby the signal from the star and planet are differentiated using knowledge of the planetary ephemerides, allows us to measure atmospheric signals from the planet at levels of at least 10(-4) relative to the star. This can only be achieved in conjunction with a carefully designed stable payload and satellite platform. It is also necessary to provide broad instantaneous wavelength coverage to detect as many molecular species as possible, to probe the thermal structure of the planetary atmospheres and to correct for the contaminating effects of the stellar photosphere. This requires wavelength coverage of at least 0.55 to 11 mu m with a goal of covering from 0.4 to 16 mu m. Only modest spectral resolving power is needed, with R similar to 300 for wavelengths less than 5 mu m and R similar to 30 for wavelengths greater than this. The transit spectroscopy technique means that no spatial resolution is required. A telescope collecting area of about 1 m(2) is sufficiently large to achieve the necessary spectro-photometric precision: for the Phase A study a 1.13 m(2) telescope, diffraction limited at 3 mu m has been adopted. Placing the satellite at L2 provides a cold and stable thermal environment as well as a large field of regard to allow efficient time-critical observation of targets randomly distributed over the sky. EChO has been conceived to achieve a single goal: exoplanet spectroscopy. The spectral coverage and signal-to-noise to be achieved by EChO, thanks to its high stability and dedicated design, would be a game changer by allowing atmospheric composition to be measured with unparalleled exactness: at least a factor 10 more precise and a factor 10 to 1000 more accurate than current observations. This would enable the detection of molecular abundances three orders of magnitude lower than currently possible and a fourfold increase from the handful of molecules detected to date. Combining these data with estimates of planetary bulk compositions from accurate measurements of their radii and masses would allow degeneracies associated with planetary interior modelling to be broken, giving unique insight into the interior structure and elemental abundances of these alien worlds. EChO would allow scientists to study exoplanets both as a population and as individuals. The mission can target super-Earths, Neptune-like, and Jupiter-like planets, in the very hot to temperate zones (planet temperatures of 300-3000 K) of F to M-type host stars. The EChO core science would be delivered by a three-tier survey. The EChO Chemical Census: This is a broad survey of a few-hundred exoplanets, which allows us to explore the spectroscopic and chemical diversity of the exoplanet population as a whole. The EChO Origin: This is a deep survey of a subsample of tens of exoplanets for which significantly higher signal to noise and spectral resolution spectra can be obtained to explain the origin of the exoplanet diversity (such as formation mechanisms, chemical processes, atmospheric escape). The EChO Rosetta Stones: This is an ultra-high accuracy survey targeting a subsample of select exoplanets. These will be the bright "benchmark" cases for which a large number of measurements would be taken to explore temporal variations, and to obtain two and three dimensional spatial information on the atmospheric conditions through eclipse-mapping techniques. If EChO were launched today, the exoplanets currently observed are sufficient to provide a large and diverse sample. The Chemical Census survey would consist of > 160 exoplanets with a range of planetary sizes, temperatures, orbital parameters and stellar host properties. Additionally, over the next 10 years, several new ground- and space-based transit photometric surveys and missions will come on-line (e.g. NGTS, CHEOPS, TESS, PLATO), which will specifically focus on finding bright, nearby systems. The current rapid rate of discovery would allow the target list to be further optimised in the years prior to EChO's launch and enable the atmospheric characterisation of hundreds of planets.
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2.
  • Kerzenmacher, T., et al. (författare)
  • Validation of NO2 and NO from the Atmospheric Chemistry Experiment (ACE)
  • 2008
  • Ingår i: Atmospheric Chemistry and Physics. - : Copernicus GmbH. - 1680-7316 .- 1680-7324. ; 8:19, s. 5801--5841-
  • Tidskriftsartikel (refereegranskat)abstract
    • Vertical profiles of NO2 and NO have been obtained from solar occultation measurements by the Atmospheric Chemistry Experiment (ACE), using an infrared Fourier Transform Spectrometer (ACE-FTS) and (for NO2) an ultraviolet-visible-near-infrared spectrometer, MAESTRO (Measurement of Aerosol Extinction in the Stratosphere and Troposphere Retrieved by Occultation). In this paper, the quality of the ACE-FTS version 2.2 NO2 and NO and the MAESTRO version 1.2 NO2 data are assessed using other solar occultation measurements (HALOE, SAGE II, SAGE III, POAM III, SCIAMACHY), stellar occultation measurements (GOMOS), limb measurements (MIPAS, OSIRIS), nadir measurements (SCIAMACHY), balloon-borne measurements (SPIRALE, SAOZ) and ground-based measurements (UV-VIS, FTIR). Time differences between the comparison measurements were reduced using either a tight coincidence criterion, or where possible, chemical box models. ACE-FTS NO2 and NO and the MAESTRO NO2 are generally consistent with the correlative data. The ACE-FTS and MAESTRO NO2 volume mixing ratio (VMR) profiles agree with the profiles from other satellite data sets to within about 20% between 25 and 40 km, with the exception of MIPAS ESA (for ACE-FTS) and SAGE II (for ACE-FTS (sunrise) and MAESTRO) and suggest a negative bias between 23 and 40 km of about 10%. MAESTRO reports larger VMR values than the ACE-FTS. In comparisons with HALOE, ACE-FTS NO VMRs typically (on average) agree to ±8% from 22 to 64 km and to +10% from 93 to 105 km, with maxima of 21% and 36%, respectively. Partial column comparisons for NO2 show that there is quite good agreement between the ACE instruments and the FTIRs, with a mean difference of +7.3% for ACE-FTS and +12.8% for MAESTRO.
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3.
  • Aoyama, T., et al. (författare)
  • The anomalous magnetic moment of the muon in the Standard Model
  • 2020
  • Ingår i: Physics reports. - : Elsevier BV. - 0370-1573 .- 1873-6270. ; 887, s. 1-166
  • Forskningsöversikt (refereegranskat)abstract
    • We review the present status of the Standard Model calculation of the anomalous magnetic moment of the muon. This is performed in a perturbative expansion in the fine-structure constant α and is broken down into pure QED, electroweak, and hadronic contributions. The pure QED contribution is by far the largest and has been evaluated up to and including O(α5) with negligible numerical uncertainty. The electroweak contribution is suppressed by (mμ/MW)2 and only shows up at the level of the seventh significant digit. It has been evaluated up to two loops and is known to better than one percent. Hadronic contributions are the most difficult to calculate and are responsible for almost all of the theoretical uncertainty. The leading hadronic contribution appears at O(α2) and is due to hadronic vacuum polarization, whereas at O(α3) the hadronic light-by-light scattering contribution appears. Given the low characteristic scale of this observable, these contributions have to be calculated with nonperturbative methods, in particular, dispersion relations and the lattice approach to QCD. The largest part of this review is dedicated to a detailed account of recent efforts to improve the calculation of these two contributions with either a data-driven, dispersive approach, or a first-principle, lattice-QCD approach. The final result reads aμSM = 116 591 810(43) x 10-11 and is smaller than the Brookhaven measurement by 3.7 σ. The experimental uncertainty will soon be reduced by up to a factor four by the new experiment currently running at Fermilab, and also by the future J-PARC experiment. This and the prospects to further reduce the theoretical uncertainty in the near future - which are also discussed here - make this quantity one of the most promising places to look for evidence of new physics.
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4.
  • Clerbaux, C., et al. (författare)
  • CO measurements from the ACE-FTS satellite instrument: data analysis and validation using ground-based, airborne and spaceborne observations
  • 2008
  • Ingår i: Atmospheric Chemistry and Physics. - : Copernicus GmbH. - 1680-7316 .- 1680-7324. ; 8, s. 2569-2594
  • Tidskriftsartikel (refereegranskat)abstract
    • The Atmospheric Chemistry Experiment (ACE) mission was launched in August 2003 to sound the atmosphere by solar occultation. Carbon monoxide (CO), a good tracer of pollution plumes and atmospheric dynamics, is one of the key species provided by the primary instrument, the ACE-Fourier Transform Spectrometer (ACE-FTS). This instrument performs measurements in both the CO 1-0 and 2-0 ro-vibrational bands, from which vertically resolved CO concentration profiles are retrieved, from the mid-troposphere to the thermosphere. This paper presents an updated description of the ACE-FTS version 2.2 CO data product, along with a comprehensive validation of these profiles using available observations (February 2004 to December 2006). We have compared the CO partial columns with ground-based measurements using Fourier transform infrared spectroscopy and millimeter wave radiometry, and the volume mixing ratio profiles with airborne (both high-altitude balloon flight and airplane) observations. CO satellite observations provided by nadir-looking instruments (MOPITT and TES) as well as limb-viewing remote sensors (MIPAS, SMR and MLS) were also compared with the ACE-FTS CO products. We show that the ACE-FTS measurements provide CO profiles with small retrieval errors (better than 5% from the upper troposphere to 40 km, and better than 10% above). These observations agree well with the correlative measurements, considering the rather loose coincidence criteria in some cases. Based on the validation exercise we assess the following uncertainties to the ACE-FTS measurement data: better than 15% in the upper troposphere (8–12 km), than 30% in the lower stratosphere (12–30 km), and than 25% from 30 to 100 km.
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5.
  • Concepcion Gil-Rodriguez, Maria, et al. (författare)
  • De Novo Heterozygous Mutations in SMC3 Cause a Range of Cornelia de Lange Syndrome-Overlapping Phenotypes
  • 2015
  • Ingår i: Human Mutation. - : Wiley: 12 months. - 1059-7794 .- 1098-1004. ; 36:4, s. 454-462
  • Tidskriftsartikel (refereegranskat)abstract
    • Cornelia de Lange syndrome (CdLS) is characterized by facial dysmorphism, growth failure, intellectual disability, limb malformations, and multiple organ involvement. Mutations in five genes, encoding subunits of the cohesin complex (SMC1A, SMC3, RAD21) and its regulators (NIPBL, HDAC8), account for at least 70% of patients with CdLS or CdLS-like phenotypes. To date, only the clinical features from a single CdLS patient with SMC3 mutation has been published. Here, we report the efforts of an international research and clinical collaboration to provide clinical comparison of 16 patients with CdLS-like features caused by mutations in SMC3. Modeling of the mutation effects on protein structure suggests a dominant-negative effect on the multimeric cohesin complex. When compared with typical CdLS, many SMC3-associated phenotypes are also characterized by postnatal microcephaly but with a less distinctive craniofacial appearance, a milder prenatal growth retardation that worsens in childhood, few congenital heart defects, and an absence of limb deficiencies. While most mutations are unique, two unrelated affected individuals shared the same mutation but presented with different phenotypes. This work confirms that de novo SMC3 mutations account for approximate to 1%-2% of CdLS-like phenotypes.
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6.
  • Orell-Miquel, J., et al. (författare)
  • Confirmation of an He I evaporating atmosphere around the 650-Myr-old sub-Neptune HD 235088 b (TOI-1430 b) with CARMENES
  • 2023
  • Ingår i: Astronomy and Astrophysics. - 0004-6361 .- 1432-0746. ; 677
  • Tidskriftsartikel (refereegranskat)abstract
    • HD 235088 (TOI-1430) is a young star known to host a sub-Neptune-sized planet candidate. We validated the planetary nature of HD 235088 b with multiband photometry, refined its planetary parameters, and obtained a new age estimate of the host star, placing it at 600- 800 Myr. Previous spectroscopic observations of a single transit detected an excess absorption of He I coincident in time with the planet candidate transit. Here, we confirm the presence of He I in the atmosphere of HD 235088 b with one transit observed with CARMENES. We also detected hints of variability in the strength of the helium signal, with an absorption of -0.91 ± 0.11%, which is slightly deeper (2γ) than the previous measurement. Furthermore, we simulated the He I signal with a spherically symmetric 1D hydrodynamic model, finding that the upper atmosphere of HD 235088 b escapes hydrodynamically with a significant mass loss rate of (1.5-5) × 1010 g s-1 in a relatively cold outflow, with T = 3125 ±375 K, in the photon-limited escape regime. HD 235088 b (Rp = 2.045 ± 0.075 R⊕) is the smallest planet found to date with a solid atmospheric detection - not just of He I but any other atom or molecule. This positions it a benchmark planet for further analyses of evolving young sub-Neptune atmospheres.
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7.
  • Rousseau-Nepton, L., et al. (författare)
  • SIGNALS : I. Survey description
  • 2019
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 489:4, s. 5530-5546
  • Tidskriftsartikel (refereegranskat)abstract
    • SIGNALS, the Star formation, Ionized Gas, and Nebular Abundances Legacy Survey, is a large observing programme designed to investigate massive star formation and HII regions in a sample of local extended galaxies. The programme will use the imaging Fourier transform spectrograph SITELLE at the Canada-France-Hawaii Telescope. Over 355 h (54.7 nights) have been allocated beginning in fall 2018 for eight consecutive semesters. Once completed, SIGNALS will provide a statistically reliable laboratory to investigate massive star formation, including over 50 000 resolved HII regions: the largest, most complete, and homogeneous data base of spectroscopically and spatially resolved extragalactic HII regions ever assembled. For each field observed, three datacubes covering the spectral bands of the filters SN1 (363386 nm), SN2 (482-513 nm), and SN3 (647-685 nm) are gathered. The spectral resolution selected for each spectral band is 1000, 1000, and 5000, respectively. As defined, the project sample will facilitate the study of small-scale nebular physics and many other phenomena linked to star formation at a mean spatial resolution of similar to 20 pc. This survey also has considerable legacy value for additional topics, including planetary nebulae, diffuse ionized gas, and supernova remnants. The purpose of this paper is to present a general outlook of the survey, notably the observing strategy, galaxy sample, and science requirements.
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8.
  • Tinetti, Giovanna, et al. (författare)
  • The science of EChO
  • 2010
  • Ingår i: Proceedings of the International Astronomical Union. - 1743-9213 .- 1743-9221. ; 6:S276, s. 359-370
  • Tidskriftsartikel (refereegranskat)abstract
    • The science of extra-solar planets is one of the most rapidly changing areas of astrophysics and since 1995 the number of planets known has increased by almost two orders of magnitude. A combination of ground-based surveys and dedicated space missions has resulted in 560-plus planets being detected, and over 1200 that await confirmation. NASA's Kepler mission has opened up the possibility of discovering Earth-like planets in the habitable zone around some of the 100,000 stars it is surveying during its 3 to 4-year lifetime. The new ESA's Gaia mission is expected to discover thousands of new planets around stars within 200 parsecs of the Sun. The key challenge now is moving on from discovery, important though that remains, to characterisation: what are these planets actually like, and why are they as they are In the past ten years, we have learned how to obtain the first spectra of exoplanets using transit transmission and emission spectroscopy. With the high stability of Spitzer, Hubble, and large ground-based telescopes the spectra of bright close-in massive planets can be obtained and species like water vapour, methane, carbon monoxide and dioxide have been detected. With transit science came the first tangible remote sensing of these planetary bodies and so one can start to extrapolate from what has been learnt from Solar System probes to what one might plan to learn about their faraway siblings. As we learn more about the atmospheres, surfaces and near-surfaces of these remote bodies, we will begin to build up a clearer picture of their construction, history and suitability for life. The Exoplanet Characterisation Observatory, EChO, will be the first dedicated mission to investigate the physics and chemistry of Exoplanetary Atmospheres. By characterising spectroscopically more bodies in different environments we will take detailed planetology out of the Solar System and into the Galaxy as a whole. EChO has now been selected by the European Space Agency to be assessed as one of four M3 mission candidates. © International Astronomical Union 2011.
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9.
  • Gardner, J.L., et al. (författare)
  • Comparison of nighttime nitric oxide 5.3 μm emissions in the thermosphere measured by MIPAS and SABER
  • 2007
  • Ingår i: Journal of Geophysical Research - Space Physics. - 2169-9380 .- 2169-9402. ; 112:A10
  • Tidskriftsartikel (refereegranskat)abstract
    • A comparative study of nitric oxide (NO) 5.3 μm emissions in the thermosphere measured by the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) spectrometer and the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) radiometer satellite instruments was conducted for nighttime data collected on 14 June 2003. The agreement between the data sets was very good, within ∼25% over the entire latitude range studied from −58° to + 4°. The MIPAS and SABER data were inverted to retrieve NO volume emission rates. Spectral fitting of the MIPAS data was used to determine the NO(v = 1) rotational and spin-orbit temperatures, which were found to be in nonlocal thermodynamic equilibrium (non-LTE) above 110 km. Near 110 km the rotational and spin-orbit temperatures converged, indicating the onset of equilibrium in agreement with the results of non-LTE modeling. Because of the onset of equilibrium the NO rotational and spin-orbit temperatures can be used to estimate the kinetic temperature near 110 km. The results indicate that the atmospheric model NRLMSISE-00 underestimates the kinetic temperature near 110 km for the locations investigated. The SABER instrument 5.3 μm band filter cuts off a significant fraction of the NO(Δv = 1) band, and therefore modeling of NO is necessary to predict the total band radiance. The needed correction factors were directly determined from the MIPAS data, providing validation of the modeled values used in SABER operational data processing. The correction factors were applied to the SABER data to calculate densities of NO(v = 1). A feasibility study was also conducted to investigate the use of NO 5.3 μm emission data to derive NO(v = 0) densities in the thermosphere.
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10.
  • Remsberg, E.E., et al. (författare)
  • Assessment of the quality of the Version 1.07 temperature-versus-pressure profiles of the middle atmosphere from TIMED/SABER
  • 2008
  • Ingår i: Journal of Geophysical Research - Atmospheres. - 2169-897X .- 2169-8996. ; 113:D17
  • Tidskriftsartikel (refereegranskat)abstract
    • The quality of the retrieved temperature-versus-pressure (or T(p)) profiles is described for the middle atmosphere for the publicly available Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) Version 1.07 (V1.07) data set. The primary sources of systematic error for the SABER results below about 70 km are (1) errors in the measured radiances, (2) biases in the forward model, and (3) uncertainties in the corrections for ozone and in the determination of the reference pressure for the retrieved profiles. Comparisons with other correlative data sets indicate that SABER T(p) is too high by 1–3 K in the lower stratosphere but then too low by 1 K near the stratopause and by 2 K in the middle mesosphere. There is little difference between the local thermodynamic equilibrium (LTE) algorithm results below about 70 km from V1.07 and V1.06, but there are substantial improvements/differences for the non-LTE results of V1.07 for the upper mesosphere and lower thermosphere (UMLT) region. In particular, the V1.07 algorithm uses monthly, diurnally averaged CO2 profiles versus latitude from the Whole Atmosphere Community Climate Model. This change has improved the consistency of the character of the tides in its kinetic temperature (Tk). The Tk profiles agree with UMLT values obtained from ground-based measurements of column-averaged OH and O2 emissions and of the Na lidar returns, at least within their mutual uncertainties. SABER Tk values obtained near the mesopause with its daytime algorithm also agree well with the falling sphere climatology at high northern latitudes in summer. It is concluded that the SABER data set can be the basis for improved, diurnal-to-interannual-scale temperatures for the middle atmosphere and especially for its UMLT region.
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11.
  • Rodriguez-Palmero, Agusti, et al. (författare)
  • DLG4-related synaptopathy : a new rare brain disorder
  • 2021
  • Ingår i: Genetics in Medicine. - : Elsevier BV. - 1098-3600 .- 1530-0366. ; 23:5, s. 888-899
  • Tidskriftsartikel (refereegranskat)abstract
    • PurposePostsynaptic density protein-95 (PSD-95), encoded by DLG4, regulates excitatory synaptic function in the brain. Here we present the clinical and genetic features of 53 patients (42 previously unpublished) with DLG4 variants.MethodsThe clinical and genetic information were collected through GeneMatcher collaboration. All the individuals were investigated by local clinicians and the gene variants were identified by clinical exome/genome sequencing.ResultsThe clinical picture was predominated by early onset global developmental delay, intellectual disability, autism spectrum disorder, and attention deficit–hyperactivity disorder, all of which point to a brain disorder. Marfanoid habitus, which was previously suggested to be a characteristic feature of DLG4-related phenotypes, was found in only nine individuals and despite some overlapping features, a distinct facial dysmorphism could not be established. Of the 45 different DLG4 variants, 39 were predicted to lead to loss of protein function and the majority occurred de novo (four with unknown origin). The six missense variants identified were suggested to lead to structural or functional changes by protein modeling studies.ConclusionThe present study shows that clinical manifestations associated with DLG4 overlap with those found in other neurodevelopmental disorders of synaptic dysfunction; thus, we designate this group of disorders as DLG4-related synaptopathy.
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  • Arnardottir, E. S., et al. (författare)
  • Variability in recording and scoring of respiratory events during sleep in Europe: a need for uniform standards
  • 2016
  • Ingår i: Journal of Sleep Research. - : Wiley. - 0962-1105. ; 25:2, s. 144-157
  • Tidskriftsartikel (refereegranskat)abstract
    • Uniform standards for the recording and scoring of respiratory events during sleep are lacking in Europe, although many centres follow the published recommendations of the American Academy of Sleep Medicine. The aim of this study was to assess the practice for the diagnosis of sleep-disordered breathing throughout Europe. A specially developed questionnaire was sent to representatives of the 31 national sleep societies in the Assembly of National Sleep Societies of the European Sleep Research Society, and a total of 29 countries completed the questionnaire. Polysomnography was considered the primary diagnostic method for sleep apnea diagnosis in 10 (34.5%), whereas polygraphy was used primarily in six (20.7%) European countries. In the remaining 13 countries (44.8%), no preferred methodology was used. Fifteen countries (51.7%) had developed some type of national uniform standards, but these standards varied significantly in terms of scoring criteria, device specifications and quality assurance procedures between countries. Only five countries (17.2%) had published these standards. Most respondents supported the development of uniform recording and scoring criteria for Europe, which might be based partly on the existing American Academy of Sleep Medicine rules, but also take into account differences in European practice when compared to North America. This survey highlights the current varying approaches to the assessment of patients with sleep-disordered breathing throughout Europe and supports the need for the development of practice parameters in the assessment of such patients that would be suited to European clinical practice.
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15.
  • Krupko, Yu., et al. (författare)
  • Kerr nonlinearity in a superconducting Josephson metamaterial
  • 2018
  • Ingår i: Physical Review B. - : American Physical Society. - 2469-9950 .- 2469-9969. ; 98:9
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a detailed experimental and theoretical analysis of the dispersion and nonlinear Kerr frequency shifts of plasma modes in a one-dimensional Josephson junction chain containing 500 superconducting quantum interfence devices in the regime of weak nonlinearity. The measured low-power dispersion curve agrees perfectly with the theoretical model if we take into account the Kerr renormalization of the bare frequencies and the long-range nature of the island charge screening by a remote ground plane. We measured the self- and cross-Kerr shifts for the frequencies of the eight lowest modes in the chain. We compare the measured Kerr coefficients with theory and find good agreement.
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18.
  • Sedaghati, Elyar, et al. (författare)
  • A spectral survey of WASP-19b with ESPRESSO
  • 2021
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 505:1, s. 435-458
  • Forskningsöversikt (refereegranskat)abstract
    • High-resolution precision spectroscopy provides a multitude of robust techniques for probing exoplanetary atmospheres. We present multiple VLT/ESPRESSO transit observations of the hot-Jupiter exoplanet WASP-19b with previously published but disputed atmospheric features from lowresolution studies. Through spectral synthesis and modelling of the Rossiter-McLaughlin (RM) effect we calculate stellar, orbital and physical parameters for the system. From narrow-band spectroscopy we do not detect any of HI, FeI, MgI, CaI, NaI, and KI neutral species, placing upper limits on their line contrasts. Through cross-correlation analyses with atmospheric models, we do not detect Fe I and place a 3σ upper limit of log (XFe/X⊙) ≈ -1.83 ± 0.11 on its mass fraction, from injection and retrieval. We show the inability to detect the presence of H2O for known abundances, owing to lack of strong absorption bands, as well as relatively low S/N ratio. We detect a barely significant peak (3.02±0.15 σ) in the cross-correlation map for TiO, consistent with the sub-solar abundance previously reported. This is merely a hint for the presence of TiO and does not constitute a confirmation. However, we do confirm the presence of previously observed enhanced scattering towards blue wavelengths, through chromatic RM measurements, pointing to a hazy atmosphere. We finally present a reanalysis of low-resolution transmission spectra of this exoplanet, concluding that unocculted starspots alone cannot explain previously detected features. Our reanalysis of the FORS2 spectra of WASP-19b finds a ~100× sub-solar TiO abundance, precisely constrained to log XTiO ≈ -7.52 ± 0.38, consistent with the TiO hint from ESPRESSO. We present plausible paths to reconciliation with other seemingly contradicting results.
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19.
  • Vandaele, Ann Carine, et al. (författare)
  • Martian dust storm impact on atmospheric H2O and D/H observed by ExoMars Trace Gas Orbiter
  • 2019
  • Ingår i: Nature. - : Springer. - 1476-4687 .- 1476-4687 .- 0028-0836. ; 568:7753, s. 521-525
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
    • Global dust storms on Mars are rare1,2 but can affect the Martian atmosphere for several months. They can cause changes in atmospheric dynamics and inflation of the atmosphere3, primarily owing to solar heating of the dust3. In turn, changes in atmospheric dynamics can affect the distribution of atmospheric water vapour, with potential implications for the atmospheric photochemistry and climate on Mars4. Recent observations of the water vapour abundance in the Martian atmosphere during dust storm conditions revealed a high-altitude increase in atmospheric water vapour that was more pronounced at high northern latitudes5,6, as well as a decrease in the water column at low latitudes7,8. Here we present concurrent, high-resolution measurements of dust, water and semiheavy water (HDO) at the onset of a global dust storm, obtained by the NOMAD and ACS instruments onboard the ExoMars Trace Gas Orbiter. We report the vertical distribution of the HDO/H2O ratio (D/H) from the planetary boundary layer up to an altitude of 80 kilometres. Our findings suggest that before the onset of the dust storm, HDO abundances were reduced to levels below detectability at altitudes above 40 kilometres. This decrease in HDO coincided with the presence of water-ice clouds. During the storm, an increase in the abundance of H2O and HDO was observed at altitudes between 40 and 80 kilometres. We propose that these increased abundances may be the result of warmer temperatures during the dust storm causing stronger atmospheric circulation and preventing ice cloud formation, which may confine water vapour to lower altitudes through gravitational fall and subsequent sublimation of ice crystals3. The observed changes in H2O and HDO abundance occurred within a few days during the development of the dust storm, suggesting a fast impact of dust storms on the Martian atmosphere.
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  • Bender, Stefan, et al. (författare)
  • Comparison of nitric oxide measurements in the mesosphere and lower thermosphere from ACE-FTS, MIPAS, SCIAMACHY, and SMR
  • 2015
  • Ingår i: Atmospheric Measurement Techniques. - : Copernicus GmbH. - 1867-1381 .- 1867-8548. ; 8:10, s. 4171-4195
  • Tidskriftsartikel (refereegranskat)abstract
    • We compare the nitric oxide measurements in the mesosphere and lower thermosphere (60 to 150 km) from four instruments: the Atmospheric Chemistry Experiment–Fourier Transform Spectrometer (ACE-FTS), the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS), the SCanning Imaging Absorption spectroMeter for Atmospheric CHartographY (SCIAMACHY), and the Sub-Millimetre Radiometer (SMR). We use the daily zonal mean data in that altitude range for the years 2004–2010 (ACE-FTS), 2005–2012 (MIPAS), 2008–2012 (SCIAMACHY), and 2003–2012 (SMR).We first compare the data qualitatively with respect to the morphology, focussing on the major features, and then compare the time series directly and quantitatively. In three geographical regions, we compare the vertical density profiles on coincident measurement days. Since none of the instruments delivers continuous daily measurements in this altitude region, we carried out a multi-linear regression analysis. This regression analysis considers annual and semi-annual variability in the form of harmonic terms and inter-annual variability by responding linearly to the solar Lyman-α radiation index and the geomagnetic Kp index. This analysis helps to find similarities and differences in the individual data sets with respect to the inter-annual variations caused by geomagnetic and solar variability.
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23.
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24.
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25.
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26.
  • Grote, Ludger, 1964, et al. (författare)
  • 10-year anniversary of the European Somnologist examination - A historic overview and critical appraisal
  • 2022
  • Ingår i: Journal of Sleep Research. - : Wiley. - 0962-1105 .- 1365-2869. ; 31:4
  • Tidskriftsartikel (refereegranskat)abstract
    • The European Somnologist certification programme was developed by the European Sleep Research Society to improve patient care in sleep medicine by providing an independent evaluation of theoretical and practical knowledge. The examination of eligible experts plays a key role in this procedure. A process was started more than 15 years ago to create the European sleep medicine curriculum, eligibility criteria for certification, and sleep centre accreditation criteria. The process was characterised by interdisciplinary collaboration, consensus, and achieving new solutions. During the past 10 years, experience has been gained by the examination and certification of more than 1000 sleep medicine experts from more than 50 countries. The process has continuously been improved. However, as the programme was designed and administered mainly by medical experts in the field, systematic influence from teaching and pedagogic experts was partially underrepresented. The current critical appraisal pinpoints several missing links in the process - mainly as a missing constructive alignment between learning objectives, learning and teaching activities, and the final assessment. A series of suggestions has been made to further improve the ESRS certification programme.
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27.
  • Harding, P., et al. (författare)
  • Wind regime changes in the Euro-Atlantic region driven by Late-Holocene Grand Solar Minima
  • 2022
  • Ingår i: Climate Dynamics. - : Springer Science and Business Media LLC. - 0930-7575 .- 1432-0894.
  • Tidskriftsartikel (refereegranskat)abstract
    • Understanding atmospheric response to radiative forcing, including the intensity and distribution of wind patterns is critical as this might have important implications in the coming decades. Long-term episodes of reduced solar activity (i.e. Grand Solar Minima, GSM) have triggered rapid climate change in the past, recorded in proxy-based records, including varved sediments from Meerfelder Maar, Germany, where the Homeric GSM (~ 2800 years ago) was studied. This study reconstructs windy conditions during the same GSM from Diss Mere, another varved record in England, to support the solar-wind linkage in the North Atlantic-European region. We use diatoms as proxies for windiness and support the palaeolimnological and palaeoclimate interpretation with a multi-proxy approach, including sedimentological, geochemical, and biological (chironomids and pollen) evidence. The diatom assemblage documents a shift from Pantocsekiella ocellata dominance to Stephanodiscus parvus and Lindavia comta, indicating a shift to more turbulent waters from ~ 2767 ± 28, linked to increased windiness. This shift is synchronous with changes in 14C production, linked to solar activity changes during the GSM. Both proxy records reflect a rapid and synchronous atmospheric response (i.e. stronger winds) at the onset and during the GSM in the North Atlantic and continental Europe. In order to test whether this solar-wind linkage is consistent during other GSMs and to understand the underlying climate dynamics, we analyse the wind response to solar forcing at the two study sites during the Little Ice Age, a period that includes several GSMs. For this, we have used a reconstruction based on a 1200-year-long simulation with an isotope-enabled climate model. Our study suggests that wind anomalies in the North Atlantic-European sector may relate to an anomalous atmospheric circulation in response to long-term solar forcing leading to north-easterlies modulated by the East Atlantic pattern.
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28.
  • Krab, Lianne C., et al. (författare)
  • Delineation of phenotypes and genotypes related to cohesin structural protein RAD21
  • 2020
  • Ingår i: Human Genetics. - : Springer Science and Business Media LLC. - 0340-6717 .- 1432-1203. ; 139:5, s. 575-592
  • Tidskriftsartikel (refereegranskat)abstract
    • RAD21 encodes a key component of the cohesin complex, and variants in RAD21 have been associated with Cornelia de Lange Syndrome (CdLS). Limited information on phenotypes attributable to RAD21 variants and genotype–phenotype relationships is currently published. We gathered a series of 49 individuals from 33 families with RAD21 alterations [24 different intragenic sequence variants (2 recurrent), 7 unique microdeletions], including 24 hitherto unpublished cases. We evaluated consequences of 12 intragenic variants by protein modelling and molecular dynamic studies. Full clinical information was available for 29 individuals. Their phenotype is an attenuated CdLS phenotype compared to that caused by variants in NIPBL or SMC1A for facial morphology, limb anomalies, and especially for cognition and behavior. In the 20 individuals with limited clinical information, additional phenotypes include Mungan syndrome (in patients with biallelic variants) and holoprosencephaly, with or without CdLS characteristics. We describe several additional cases with phenotypes including sclerocornea, in which involvement of the RAD21 variant is uncertain. Variants were frequently familial, and genotype–phenotype analyses demonstrated striking interfamilial and intrafamilial variability. Careful phenotyping is essential in interpreting consequences of RAD21 variants, and protein modeling and dynamics can be helpful in determining pathogenicity. The current study should be helpful when counseling families with a RAD21 variation.
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29.
  • López-Puertas, M., et al. (författare)
  • Non-local thermodynamic equilibrium limb radiances for the mipas instrument on Envisat-1
  • 1998
  • Ingår i: Journal of Quantitative Spectroscopy and Radiative Transfer. - 0022-4073 .- 1879-1352. ; 59:3-5, s. 377-403
  • Tidskriftsartikel (refereegranskat)abstract
    • An evaluation of the effects that the assumption of local thermodynamic equilibrium (LTE) has on the retrieval of pressure, temperature and the five primary target gases (O3, H2O, CH4, N2O, and HNO3) from spectra to be taken by Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) on the Envisat-1 platform has been conducted. For doing so, non-LTE and LTE limb radiances in the spectral range of 680–2275 cm−1 (4.15–14.6 μm) with a resolution of 0.05 cm−1 at tangent heights from 10 to 70 km have been computed. These calculations included the most updated non-LTE populations of a large number of vibrational levels of the CO2, O3, H2O, CH4, N2O and HNO3 molecules which cause the most prominent atmospheric infrared emissions. A discussion of the most important non-LTE effects on the limb radiances as well as on the retrievals of pressure-temperature and volume mixing ratios of O3, H2O, CH4, N2O, and HNO3 is presented, together with the most important non-LTE issues that could be studied with the future coming of MIPAS data.
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30.
  • López-Puertas, M., et al. (författare)
  • Non-LTE studies for the analysis of MIPAS/ENVISAT data
  • 2002
  • Ingår i: Proceedings of SPIE, the International Society for Optical Engineering. - : SPIE. - 0277-786X .- 1996-756X. ; 4539, s. 381-395
  • Tidskriftsartikel (refereegranskat)abstract
    • The Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) is a high-resolution limb sounder on board the European polar platform ENVISAT, scheduled for launch late in 2001. Three main characteristics converge in MIPAS which make it a very useful instrument for non-LTE studies: its wide spectral coverage (4.15-14.6 μm or 680-2275 cm-1); high spectral resolution (0.03 cm-1), and high sensitivity; all of this in addition to its global spatial coverage. In this paper we present an overview of the non-LTE studies that have been carried out in preparation for the analysis of MIPAS data, including the evaluation of non-LTE effects in the operational processing, focussed in the stratosphere, and the retrieval of species that normally emit under non-LTE conditions. The current mission plan for measuring the non-LTE upper atmosphere is described, as well as the general purpose non-LTE retrieval scheme developed for analyzing those measurements.
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31.
  • Manuilova, R.O., et al. (författare)
  • Modelling of non-LTE limb spectra of i.r. ozone bands for the MIPAS space experiment
  • 1998
  • Ingår i: Journal of Quantitative Spectroscopy and Radiative Transfer. - 0022-4073 .- 1879-1352. ; 59:3-5, s. 405-422
  • Tidskriftsartikel (refereegranskat)abstract
    • A new model for calculating the populations of the ozone vibrational states under non-LTE (Local Thermodynamic Equilibrium) conditions is presented. In the model, 23 vibrational levels of the O3 molecule, as well as three vibrational levels of the O2 molecule and two vibrational levels of the N2 molecule, are considered. The radiative transfer at the break-down of LTE was treated explicitly for 150 000 ro-vibrational transitions. The populations obtained were used to calculate limb radiances in various spectral regions of the 4.8 and 9.6 μm bands. Test retrievals of O3 vertical volume mixing ratio (VMR) profiles with a radiance model disregarding non-LTE were performed in order to assess the potential impact of non-LTE effects on the retrieval of the O3 abundances from MIPAS (Michelson Interferometer for Passive Atmospheric Sounding) measurements.
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32.
  • Mlynczak, Martin G., et al. (författare)
  • Observations of infrared radiative cooling in the thermosphere on daily to multiyear timescales from the TIMED/SABER instrument
  • 2010
  • Ingår i: Journal of Geophysical Research - Space Physics. - 2169-9380 .- 2169-9402. ; 115:A3
  • Tidskriftsartikel (refereegranskat)abstract
    • We present observations of the infrared radiative cooling by carbon dioxide (CO2) and nitric oxide (NO) in Earth's thermosphere. These data have been taken over a period of 7 years by the Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) instrument on the NASA Thermosphere-Ionosphere-Mesosphere Energetics and Dynamics (TIMED) satellite and are the dominant radiative cooling mechanisms for the thermosphere. From the SABER observations we derive vertical profiles of radiative cooling rates (W m−3), radiative fluxes (W m−2), and radiated power (W). In the period from January 2002 through January 2009, we observe a large decrease in the cooling rates, fluxes, and power consistent with the declining phase of solar cycle 23. The power radiated by NO during 2008 when the Sun exhibited few sunspots was nearly one order of magnitude smaller than the peak power observed shortly after the mission began. Substantial short-term variability in the infrared emissions is also observed throughout the entire mission duration. Radiative cooling rates and radiative fluxes from NO exhibit fundamentally different latitude dependence than do those from CO2, with the NO fluxes and cooling rates being largest at high latitudes and polar regions. The cooling rates are shown to be derived relatively independent of the collisional and radiative processes that drive the departure from local thermodynamic equilibrium (LTE) in the CO2 15 μm and the NO 5.3 μm vibration-rotation bands. The observed NO and CO2 cooling rates have been compiled into a separate data set and represent a climate data record that is available for use in assessments of radiative cooling in upper atmosphere general circulation models.
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33.
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35.
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36.
  • Von Clarmann, T., et al. (författare)
  • A blind test retrieval experiment for infrared limb emission spectrometry
  • 2003
  • Ingår i: Journal of Geophysical Research - Atmospheres. - 2169-897X .- 2169-8996. ; 108:D23
  • Tidskriftsartikel (refereegranskat)abstract
    • The functionality and characteristics of six different data processors (i.e., retrieval codes in their actual software and hardware environment) for analysis of high-resolution limb emission infrared spectra recorded by the space-borne Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) have been validated by means of a blind test retrieval experiment based on synthetic spectra. For this purpose a self-consistent set of atmospheric state parameters, including pressure, temperature, vibrational temperatures, and abundances of trace gases and aerosols, has been generated and used as input for radiative transfer calculations for MIPAS measurement geometry and configuration. These spectra were convolved with the MIPAS field of view, spectrally degraded by the MIPAS instrument line shape, and, finally, superimposed with synthetic measurement noise. These synthetic MIPAS measurements were distributed among the participants of the project “Advanced MIPAS level-2 data analysis” (AMIL2DA), who performed temperature and species abundance profile retrievals by inverse radiative transfer calculations. While the retrieved profiles of atmospheric state parameters reflect some characteristics of the individual data processors, it was shown that all the data processors under investigation are capable of producing reliable results in the sense that deviations of retrieved results from the reference profiles are within the margin that is consistent with analytical error estimation.
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37.
  • Winick, Jeremy R., et al. (författare)
  • Thermospheric infrared radiance response to the April 2002 geomagnetic storm from SABER infrared and GUVI ultraviolet limb data
  • 2004
  • Ingår i: Proceedings of SPIE, the International Society for Optical Engineering. - : SPIE. - 0277-786X .- 1996-756X. ; 5235, s. 250-263
  • Tidskriftsartikel (refereegranskat)abstract
    • The SABER instrument on TIMED continuously measures certain infrared limb radiance profiles with unprecedented sensitivity. Among these are emissions of CO 2 v 3 at 4.3 μm, routinely recorded to tangent heights of ∼140-150 km, and NO at 5.3 μm, seen to above 200 km. Both of these are greatly enhanced during periods of strong auroral activity, when they can be measured to ∼200 km and ∼300 km, respectively. We use these infrared channels of SABER and coincident far ultraviolet (FUV) measurements from GUVI on TIMED, to study the geomagnetic storm of April 2002. These all give a consistent measure of auroral energy input into the lower thermosphere at high latitudes. Emission in yet another SABER channel, near 2.0 μm, correlates well with enhanced electron energy deposition. We also have, in the 5.3-μm emissions from the long-lived population of aurorally produced NO, a tracer of how this energy is transported equatorward and released over an extended period of time, a few days. In this paper, we discuss the global patterns of energy deposition into the expanded auroral oval, its transport to lower latitudes, and its loss as revealed by the NO 5.3-μm emissions.
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