| 1. |
- Andersson, Magnus, et al.
(författare)
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Fiskbestånd och miljö i hav och sötvatten : Resurs- och miljööversikt 2012
- 2012
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Detta är den nionde utgåvan av den samlade översikten över fisk- och kräftdjursbeståndens status i våra vatten. Kunskap om fiskbestånden och miljön är en förutsättning för att utnyttjandet av fiskresurserna skall bli bärkraftigt. För svenska vattenområden beskrivs miljöutvecklingen i ett ekosystemsperspektiv, dels för att tydliggöra fiskens ekologiska roll och beskriva yttre miljöfaktorer som påverkar fiskbestånden, dels för att belysa fiskets effekter på miljön.Fiskbestånd och miljö i hav och sötvatten är utarbetad av Sveriges lantbruksuniversitet (SLU), Institutionen för akvatiska resurser (SLU Aqua), på uppdrag av Havs- och vattenmyndigheten. Rapporten sammanfattar utveckling och beståndsstatus för de kommersiellt viktigaste fisk- och kräftdjursarterna i våra vatten. Bedömningar och förvaltningsråd är baserade på Internationella Havsforskningsrådets (ICES) rådgivning, SLU Aquas nationella och regionala provfiskedata, samt yrkesfiskets rapportering.
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| 2. |
- Bryhn, Andreas, et al.
(författare)
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A continuous involvement of stakeholders promotes the ecosystem approach to fisheries in the 8-fjords area on the Swedish west coast
- 2017
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Ingår i: ICES Journal of Marine Science. - : Oxford University Press (OUP). - 1054-3139 .- 1095-9289. ; 74, s. 431–442-
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Tidskriftsartikel (refereegranskat)abstract
- The coastal marine environment in the 8-fjords area on the Swedish west coast has been subjected to various stakeholder co-management initiatives since 1999. Stakeholders and authorities have acted by supporting and implementing gradually stricter fishing restrictions following the collapse in the 1970s of several demersal fish stocks and their apparent lack of recovery. Moreover, concerns have been raised regarding a locally sharp depletion of eelgrass meadows, in addition to an apparent increase in the number of seals and cormorants. The present 8-fjords initiative applies a cross-sector approach to environmental management and thus also addresses various types of environmental pollution. This study has compared the environmental work around the 8-fjords to 15 principles regarding the ecosystem approach to fisheries (EAF). The main strength that has been identified among the EAF principles is the continuous involvement of stakeholders. Among weaknesses in the EAF is the scarcity of suitable indicators that are necessary for appropriate monitoring, especially biomasses of functional groups as well as economic and social indicators. Many environmental problems in the fjords remain and it is possible that improved adherence to EAF principles will facilitate solving some problems and alleviating others. Moreover, the application of the EAF in practice in the 8-fjords can serve as a guiding example for co-managing other aquatic ecosystems towards ecological, economic, and social sustainability. The experiences from the 8-fjords initiative, including its extensive stakeholder involvement, may serve as a practical EAF example to be studied by researchers and managers globally.
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| 3. |
- Östman, Örjan, et al.
(författare)
-
Förvaltningsmål för nationellt förvaltade fiskbestånd : En översikt av kvantitativa mål
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Fisk - och skaldjursbestånd som i huvudsak är begränsad e till svenska nationella vat- ten förvaltas av svenska myndigheter och organisationer. Dessa bestånd kan i motsats till internationellt exploaterade och förvaltade arter utnyttjas av flera olika aktörer (t.ex. kommersiellt - och fritidsfiske) . Olika grupper av aktö rer kan ha olika syn på vad som är de lämpligaste långsiktiga förvaltningsmålen (t.ex. stor avkastning vs. stora individer). För dessa nationella bestånd är ofta datatillgången sämre än för in- ternationella bestånd, och ofta saknas tydliga mätbara förvaltni ngsmål, vilket resul- terar i en mindre effektiv förvaltning. Syftet med denna rapport är att ge en överblick över tillgängliga kvantitativa förvaltningsmål med tillhörande metoder som är lämp- liga för ett långsiktigt hållbart utnyttjande av nationella fisk - och skaldjursbestånd. Vi identifierar tre huvudkategorier av kvantitativa förvaltningsmål: 1) Långsiktigt hållbar avkastning, som kräver detaljerade data från många olika källor . 2) Minini- våer av biomassa - eller abundansindex, eller ett specifikt förhållan de mellan fångst och biomassaindex, vilket kräver pålitlig övervaknings - eller fångstdata. 3) "Natur- lik" eller "önskvärd" demografisk struktur, vilket kräver information om egenskaper så som storlek, ålder, och könsmognad. Alla tre typer na av mål har sina förtjänster och nackdelar. Mål för hållbar avkastning och biomassa -index tar inte hänsyn till storleksstruktur, och vice versa, och olika mål kräver olika typer av indata. Vi gör en översikt av vilka förvaltningsmål som kan vara lämpliga för olika typer av nationellt förvaltade fisk - och skaldjursbestånd. För närvarande är aktuell a data i allmänhet allt- för begränsade för att föreslå specifika förvaltningsmål för de flesta bestånd som kan komma i fråga för nationell förvaltning. Snarare betonar vi vikten av att använda flera olika mål i stället för att förlita sig på ett enda för att underlätta en hållbar användning av akvatiska resurser med hänsyn tagen till olika intressenter. Dessutom finns det ingen klar definition av vad ett nationellt bestånd är och när det är lämpligt att ha en nationell förvaltning. Därför är det viktigt att förvaltningsmålen sätts så att de kan återspegla både internationella, nationella och lokal a förutsättningar .
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| 4. |
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| 5. |
- Al-Shamkhi, Nasrin, 1985-, et al.
(författare)
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Pituitary function before and after surgery for nonfunctioning pituitary adenomas-data from the Swedish Pituitary Register.
- 2023
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Ingår i: European journal of endocrinology. - : Bioscientifica. - 1479-683X .- 0804-4643. ; 189:2, s. 217-224
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Tidskriftsartikel (refereegranskat)abstract
- Data on pre- and postoperative pituitary function in nonfunctioning pituitary adenomas (NFPA) are not consistent. We aimed to investigate pituitary function before and up to 5 years after transsphenoidal surgery with emphasis on the hypothalamic-pituitary-adrenal axis (HPA).Data from the Swedish Pituitary Register was used to analyze anterior pituitary function in 838 patients with NFPA diagnosed between 1991 and 2014. Patients who were reoperated or had received radiotherapy were excluded.Preoperative ACTH, TSH, LH/FSH, and GH deficiencies were reported in 31% (236/755), 39% (300/769), 51% (378/742), and 28% (170/604) of the patients, respectively. Preoperative median tumor volume was 5.0 (2.4-9.0) cm3. Among patients with preoperative, 1 year and 5 years postoperative data on the HPA axis (n = 428), 125 (29%) were ACTH-deficient preoperatively. One year postoperatively, 26% (32/125) of them had recovered ACTH function while 23% (70/303) patients had developed new ACTH deficiency. Thus, 1 year postoperatively, 163 (38%) patients were ACTH-deficient (P < .001 vs. preoperatively). No further increase was seen 5 years postoperatively (36%, P = .096). At 1 year postoperatively, recoveries in the TSH and LH/FSH axes were reported in 14% (33/241) and 15% (46/310), respectively, and new deficiencies in 22% (88/403) and 29% (83/288), respectively.Adrenocorticotrophic hormone deficiency increased significantly at 1 year postoperatively. Even though not significant, some patients recovered from or developed new deficiency between 1 and 5 years postoperatively. This pattern was seen in all axes. Our study emphasizes that continuous individual evaluations are needed during longer follow-up of patients operated for NFPA.
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| 6. |
- Andersson, Agnes, et al.
(författare)
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Headache Before and After Endoscopic Transsphenoidal Pituitary Tumor Surgery: A Prospective Study
- 2022
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Ingår i: Journal of Neurological Surgery Part B-Skull Base. - : Georg Thieme Verlag KG. - 2193-6331 .- 2193-634X. ; 83:suppl. 2
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Tidskriftsartikel (refereegranskat)abstract
- Objective Headache is a common symptom among patients with pituitary tumors, as it is in the general population. The aim of the study was to investigate headache as a symptom in patients with pituitary tumors before and 6 months after endoscopic transsphenoidal surgery (TSS). Design This is a prospective observational cohort study. Setting This study was conducted at university tertiary referral hospital. Participants A total of 110 adult patients underwent endoscopic TSS for pituitary tumors. Main Outcome Measures The Migraine Disability Assessment (MIDAS) questionnaire was used before and 6 months after surgery for the assessment of headache. Clinical variables with potential influence on headache were analyzed. Results Sixty-eight (62%) patients experienced headaches at least once during the 3 months before surgery. Thirty (27%) patients reported disabling headache before surgery, with younger age being an independent associated factor ( p <0.001). In patients with disabling headache before surgery, the median (interquartile range) MIDAS score improved from 78 (27-168) to 16 (2-145; p =0.049), headache frequency decreased from 45 (20-81) to 14 (4-35) days ( p =0.009), and headache intensity decreased from 6 (5-8) to 5 (4-7) ( p =0.011) after surgery. In total, 16 of the 30 (53%) patients reported a clinically relevant improvement and five (17%) a clinically relevant worsening. Four (5%) patients developed new disabling headache. No predictor for postoperative improvement of headache was identified. Conclusion In this prospective study, the results show that disabling headache improves following endoscopic TSS in a subset of patients with pituitary tumors. However, no predictive factors for improvement could be identified.
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| 7. |
- Andersson, Magnus, et al.
(författare)
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Movements, recapture rate and length increment of tagged pikeperch (Sander lucioperca) - a basis for management in large lakes
- 2015
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Ingår i: Fisheries Management and Ecology. - : Wiley. - 0969-997X .- 1365-2400. ; 22, s. 450-457
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Tidskriftsartikel (refereegranskat)abstract
- Movements, site fidelity, exploitation rate and total length (TL) increment of pikeperch, Sander lucioperca L., were studied by tagging 3977 pikeperch, of 334mm mean TL, in Lake Malaren in 1994. Fish were recaptured in gillnets, trap nets and to a lesser extent with rod and line. Total recapture rate was 30.4%, with 50% of the recaptures made within 8.4km of the release site. Movements were restricted during summer, whereas movements from shallow to deeper basins were frequent in autumn. The yearly TL increment was estimated at 99mm for fish 300mm long at release and 42mm for fish of 400mm at release. The results have direct implications for future management, as the mortality of undersized fish in the fishery; the strong site fidelity and fast growth indicate that fishery closures may be an effective measure to attain a larger stock of fish above the size limit.
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| 8. |
- Axelsson, Håkan, et al.
(författare)
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Mätning av aromatiska kolväten med DOAS. En studie av tillförlitlighets- och interferensproblem.
- 1990
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- DOAS-tekniken är en optisk fjärranalysmetod för mätning av luftföroreningar. I det projekt som här avrapporterats har tekniken utvärderats m a p mätning av lätta aromatiska kolväten. Projektet har omfattat såväl litteratur, labb och fältstudier av absorptionsegenskaper som interferenseffekter. Resultaten visar att de lätta aromatiska kolväten har ett gemensamt absorptionsband i nära UV (250-280 mm ) som med fördel kan användas i en DOAS-tillämpning. Utnyttjande detta band, kan flera av aromaterna mätas med en detektionsgräns på några µg/m3. Dock föreligger kraftiga interferenseffekter mellan i synnerhet komponenter med likartad kemisk struktur. Detta problem kan i vissa fall hanteras m h a multipel regressions analys. En förutsättning för detta är dock att inga 'okända' interferande ämnen (lös aromater) förekommer i mätsituationen.
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| 9. |
- Bergek, Sara, et al.
(författare)
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Fiskfångster och utsättningar av fisk
- 2012
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Ingår i: Vänern: årsskrift 2012. ; :73, s. 68-73
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Totalfångsten i yrkesfisket i Vänern ökade under 2011 med drygt 8 procent jämfört med 2010. Den viktigaste arten för yrkesfisket gösen, stod för cirka 32 procent av totala fångstens värde. Fångsten av siklöja och signalkräfta ökade medan fångsten av abborre, gädda, gös, öring, sik och ål minskade. De registrerade fritidsfiskarna fångade under 2011 totalt 70 ton, en minskning med 14 ton jämfört med 2010. Något fler lax- och öringsmolt sattes ut jämfört med föregående år. Även utsättningen av ål ökade, hela 605 000 stycken försträckta alternativt karantäniserade ålyngel sattes ut under 2011.
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| 10. |
- Bergström, Ulf, et al.
(författare)
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Long-term decline in northern pike (Esox lucius L.) populations in the Baltic Sea revealed by recreational angling data
- 2022
-
Ingår i: Fisheries Research. - : Elsevier BV. - 0165-7836 .- 1872-6763. ; 251
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Tidskriftsartikel (refereegranskat)abstract
- In the Baltic Sea, the large predatory fish northern pike (Esox lucius L.) is important for both recreational fisheries and ecosystem functioning. As existing fishery-independent surveys do not adequately monitor pike populations, a general lack of knowledge on population status and trends poses challenges for management. Here we use recreational angling data as an alternative method to describe pike population development along the Swedish Baltic Sea coast from 1938 onwards and assess the change over time in potential mortality factors by estimating harvest by fisheries and consumption by large predators. Data from a Swedish national register on trophy-sized pike (>12 kg) showed that numbers and maximum sizes peaked in 1990-1995, after which declines in both metrics are evident. In logbooks from a sport fishing club in the Stockholm archipelago, a simultaneous decrease in maximum sizes of pike was observed, together with a decrease in the total number of pike caught per fishing day. Jointly, these data indicate a decline in the abundance of large pike since around 1990. While commercial pike fisheries in the Baltic Sea have decreased continuously since the 1950s, recreational fishing increased after 1985, when Swedish coastal waters were made open access to anglers. The declines in large pike starting in the 1990s could, thus, have been driven by an increase in mortality from recreational fisheries, which at the time primarily practiced catch and kill. Since the 2000s, bag and slot length limits, spawning closures, and a general increase in catch-and-release fishing has reduced the landings of pike in recreational fisheries. Despite these fisheries regulations and higher release rates the decline in catches of large pike has continued, indicating an effect of other mortality factors. The strong growth of grey seal (Halichoerus grypus) and great cormorant (Phalacrocorax carbo sinensis) populations suggest that predation pressure on pike has increased over time. In the Stockholm archipelago these two predators were estimated to remove 5-18 times (range based on different diet composition estimates) more pike biomass than total fisheries landings in 2014-2017. To improve the situation for northern pike in the Baltic Sea managers need to consider both fisheries restrictions and measures to decrease predation pressure and increase recruitment. Catch data from recreational fisheries may be used to evaluate such management efforts by providing information on the population development of this keystone species.
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| 11. |
- Berndt, Vendela, et al.
(författare)
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The diagnostic value of salivary cortisol and salivary cortisone in patients with suspected hypercortisolism.
- 2022
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Ingår i: Frontiers in endocrinology. - : Frontiers Media SA. - 1664-2392. ; 13
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Tidskriftsartikel (refereegranskat)abstract
- Diagnosing endogenous hypercortisolism remains a challenge, partly due to a lack of biochemical tests with good diagnostic accuracy.To evaluate the diagnostic value of salivary cortisol and cortisone in patients with suspected hypercortisolism.Retrospective study including 155 patients with adrenal incidentaloma, and 54 patients with suspected Cushing´s syndrome (CS). Salivary samples were collected at home, at 11 p.m., and at 8a.m. following an over-night dexamethasone suppression test (DST). Salivary cortisol and cortisone were measured with liquid chromatography-tandem mass spectrometry.Ten of 155 patients with adrenal incidentaloma were considered to have autonomous cortisol secretion (ACS). Using previously established cut-offs, all patients with ACS had elevated plasma-cortisol (>50 nmol/L) following DST, 9/10 had elevated late-night salivary cortisone (>15 nmol/L) whereas only 4/10 had elevated late-night salivary cortisol (LNSC; >3 nmol/L) compared to 35%, 9% and 8%, respectively, of the 145 patients with non-functioning adrenal incidentaloma. Six (60%) patents with ACS had elevated salivary cortisol and cortisone at 8a.m. following DST compared to 9% and 8%, respectively, of patients with non-functioning adrenal incidentaloma. One of 6 patients with overt CS had a normal LNSC and one had normal late-night salivary cortisone, while all had increased salivary cortisol and cortisone following DST.LNSC is not sufficiently sensitive or specific to be used for screening patients with suspected hypercortisolism. Instead, late-night salivary cortisone seems to be a promising alternative in patients with adrenal incidentaloma and salivary cortisone at 8a.m. following DST in patients with suspected CS. Larger studies are needed to confirm these findings.
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| 12. |
- Bjursten, Henrik, et al.
(författare)
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Infective endocarditis after transcatheter aortic valve implantation: a nationwide study
- 2019
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Ingår i: European Heart Journal. - : Oxford University Press (OUP). - 0195-668X .- 1522-9645. ; 40:39, s. 3263-3269
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Tidskriftsartikel (refereegranskat)abstract
- Aims Transcatheter aortic valve implantation (TAVI), now a common procedure to treat high-risk patients with severe aortic stenosis, has rapidly been expanding into younger and lower-risk populations, creating a need to better understand long-term outcome after TAVI. The aim of the present investigation was to determine the incidence, risk factors for, clinical presentation of, and outcome after prosthetic valve endocarditis (PVE) in patients treated with TAVI in a nationwide study. Methods and results Three registries were used: a national TAVI registry, a national diagnosis registry, and a national infective endocarditis registry. Combining these registries made it possible to perform a nationwide, all-comers study with independent and validated reporting of PVE in 4336 patients between 2008 and mid-2018. The risk for PVE after TAVI was 1.4% (95% confidence interval 1.0–1.8%) the first year and 0.8% (0.6–1.1%) per year thereafter. One-year survival after PVE diagnosis was 58% (49–68%), and 5-year survival was 29% (17–41%). Body surface area, estimated glomerular filtration rate <30mL/min/1.73 m2, critical pre-operative state, mean pre-procedural valve gradient, amount of contrast dye used, transapical access, and atrial fibrillation were identified as independent risk factors for PVE. Staphylococcus aureus was more common in early (<1year) PVE. Infection with S. aureus, root abscess, late PVE, and non-community acquisition was associated with higher 6-month mortality. Conclusion The incidence of PVE was similar to that of surgical bioprostheses. Compromised renal function was a strong risk factor for developing PVE. In the context of PVE, TAVI seems to be a safe option for patients.
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| 13. |
- Bjursten, Henrik, et al.
(författare)
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Late stroke after transcatheter aortic valve replacement : a nationwide study
- 2021
-
Ingår i: Scientific Reports. - : Springer Science and Business Media LLC. - 2045-2322. ; 11
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Tidskriftsartikel (refereegranskat)abstract
- Transcatheter aortic valve replacement (TAVR) is a rapidly growing field. Short-term safety and efficacy of these procedures have been studied extensively. However, little is known about the safety of these devices over time. Stroke is one feared long-term complication, and an increased stroke rate could affect guidelines for treating both the aortic stenosis and choosing antithrombotic therapy after TAVR. The primary objective was to study the incidence of stroke up to 8 years after TAVR implantation, comparing it with the risk of stroke in the general population. Secondary objectives were to study risk factors for late stroke and to study outcomes after stroke. A nationwide, all-comers study of patients who underwent TAVR in Sweden 2008–2018 was performed. The study was based on data from three national registries: a TAVR registry, a stroke registry, and a diagnosis registry. The main outcome was stroke incidence 30-days or more after TAVR implantation and was compared to a standardized incidence. The annual risk for stroke varied between 2.0% and 3.1% as compared to 1.5% and 1.9% in an age- and sex-matched cohort. Risk factors for developing stroke were reduced renal function, diabetes, history of stroke, age, and male sex. The 1-year mortality after stroke was 44%. This study demonstrated an increased rate of stroke after TAVR, but the findings suggest that this can in part be attributed to the group’s higher frequency of pre-disposing risk factors.
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| 14. |
- Bridel, Claire, et al.
(författare)
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Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology : A Systematic Review and Meta-analysis
- 2019
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Ingår i: JAMA Neurology. - : American Medical Association (AMA). - 2168-6149 .- 2168-6157. ; 76:9, s. 1035-1048
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Forskningsöversikt (refereegranskat)abstract
- Importance Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number of neurological conditions compared with healthy controls (HC) and is a candidate biomarker for neuroaxonal damage. The influence of age and sex is largely unknown, and levels across neurological disorders have not been compared systematically to date.Objectives To assess the associations of age, sex, and diagnosis with NfL in CSF (cNfL) and to evaluate its potential in discriminating clinically similar conditions.Data Sources PubMed was searched for studies published between January 1, 2006, and January 1, 2016, reporting cNfL levels (using the search terms neurofilament light and cerebrospinal fluid) in neurological or psychiatric conditions and/or in HC.Study Selection Studies reporting NfL levels measured in lumbar CSF using a commercially available immunoassay, as well as age and sex.Data Extraction and Synthesis Individual-level data were requested from study authors. Generalized linear mixed-effects models were used to estimate the fixed effects of age, sex, and diagnosis on log-transformed NfL levels, with cohort of origin modeled as a random intercept.Main Outcome and Measure The cNfL levels adjusted for age and sex across diagnoses.Results Data were collected for 10 059 individuals (mean [SD] age, 59.7 [18.8] years; 54.1% female). Thirty-five diagnoses were identified, including inflammatory diseases of the central nervous system (n = 2795), dementias and predementia stages (n = 4284), parkinsonian disorders (n = 984), and HC (n = 1332). The cNfL was elevated compared with HC in a majority of neurological conditions studied. Highest levels were observed in cognitively impaired HIV-positive individuals (iHIV), amyotrophic lateral sclerosis, frontotemporal dementia (FTD), and Huntington disease. In 33.3% of diagnoses, including HC, multiple sclerosis, Alzheimer disease (AD), and Parkinson disease (PD), cNfL was higher in men than women. The cNfL increased with age in HC and a majority of neurological conditions, although the association was strongest in HC. The cNfL overlapped in most clinically similar diagnoses except for FTD and iHIV, which segregated from other dementias, and PD, which segregated from atypical parkinsonian syndromes.Conclusions and Relevance These data support the use of cNfL as a biomarker of neuroaxonal damage and indicate that age-specific and sex-specific (and in some cases disease-specific) reference values may be needed. The cNfL has potential to assist the differentiation of FTD from AD and PD from atypical parkinsonian syndromes.
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| 15. |
- Bryhn, Andreas, et al.
(författare)
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Modelling the biomass of functional groups of fish in an archipelago bay of the Baltic Sea
- 2013
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Ingår i: Ecological Modelling. - : Elsevier BV. - 0304-3800 .- 1872-7026. ; 269, s. 86-97
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Tidskriftsartikel (refereegranskat)abstract
- Fish biomass estimates in European coastal waters are necessary for several reasons, e.g., for meeting requirements in legislation and international agreements, for establishing sustainable outtakes of the resources, for developing management plans and for assessing the ecological and environmental status of coastal waters. This study estimated piscivorous and non-piscivorous fish biomass as well as total fish biomass in Kvadofjarden Bay on the Swedish Baltic Sea coast using dynamic foodweb modelling. Weight-per-unit-effort data from the coastal fish monitoring program in the area together with a range of abiotic variables (including salinity and total phosphorus) were used as drivers for the CoastWeb model. To further refine the estimates of fish biomass, we complemented the model by using data from nearby areas on the ratio of piscivorous to non-piscivorous fish for those size classes not representatively sampled by the monitoring gear (fish < 12 cm). Piscivorous fish biomass in the area was estimated at 10-14 tonnes (4.6-6.5 kg/ha), non-piscivorous fish biomass at 105-139 tonnes (47-62 kg/ha) and the subsequent total fish biomass was estimated at 115-154 tonnes (52-69 kg/ha). The estimated range of total fish biomass was comparable with findings from other investigations on the Swedish Baltic Sea coast which used a coarser methodology. The method presented in this paper can be used for making biomass estimates in other coastal waters where passive gears are used to monitor the local fish communities, and could thus serve a range of purposes for assessing the production and status of fish in coastal waters. (C) 2013 Elsevier B.V. All rights reserved.
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| 16. |
- Faulks, Leanne, et al.
(författare)
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Intraspecific Niche Variation Drives Abundance-Occupancy Relationships in Freshwater Fish Communities
- 2015
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Ingår i: American Naturalist. - : University of Chicago Press. - 0003-0147 .- 1537-5323. ; 186:2, s. 272-283
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Tidskriftsartikel (refereegranskat)abstract
- A positive relationship between occupancy and average local abundance of species is found in a variety of taxa, yet the mechanisms driving this association between abundance and occupancy are still enigmatic. Here we show that freshwater fishes exhibit a positive abundance-occupancy relationship across 125 Swedish lakes. For a subset of 9 species from 11 lakes, we estimated species-specific diet breadth from stable isotopes, within-lake habitat breadth from catch data for littoral and pelagic nets, adaptive potential from genetic diversity, abiotic niche position, and dispersal capacity. Average local abundance was mainly positively associated with both within-lake habitat and diet breadth, that is, species with larger intraspecific variation in niche space had higher abundances. No measure was a good predictor of occupancy, indicating that occupancy may be more directly related to abundance or abiotic conditions than to niche breadth per se. This study suggests a link between intraspecific niche variation and a positive abundance-occupancy relationship and implies that management of freshwater fish communities, whether to conserve threatened or control invasive species, should initially be aimed at niche processes.
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| 17. |
- Guné, Henrik, et al.
(författare)
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Impact of ABO blood group on bleeding complications after surgery for acute type A aortic dissection
- 2021
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Ingår i: Blood Coagulation and Fibrinolysis. - 1473-5733. ; 32:4, s. 253-258
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Tidskriftsartikel (refereegranskat)abstract
- Excessive bleeding is a serious complication associated with impaired survival after surgery for acute type A aortic dissection (ATAAD). Different ABO blood groups are associated with variable levels of circulating von Willebrand factor and therefore potentially altered risks of surgical haemorrhage. The current study aimed to assess the impact of blood group on bleeding complications after ATAAD surgery. This was a retrospective cohort study including 336 patients surgically treated for ATAAD between January 2004 and January 2019. Patients with blood group O were compared with non-O patients. In total, 152 blood group O patients were compared with 184 non-O patients. There were no differences in rates of massive bleeding (27.0 vs. 25.5%, P = 0.767) or re-exploration for bleeding (16.4 vs. 13.0%, P = 0.379) in blood group O and non-O patients, respectively. Median chest tube output 12 h after surgery was 520 ml (350-815 ml) in blood group O and 490 ml (278-703 ml) in non-O patients (P = 0.229). Blood group O patients received more fibrinogen concentrate (6.1 ± 4.0 vs. 4.9 ± 3.3 g, P = 0.023) but administered units of packed red blood cells [5 (2-8) vs. 4 (2-9) U, P = 0.736], platelets [4 (2-4) vs. 3 (2-5) U, P = 0.521] or plasma [4 (1-7) vs. 4 (0-7) U, P = 0.562] were similar. This study could not demonstrate any association between blood group and bleeding after surgery for ATAAD. It cannot be ruled out that potential differences were levelled out by blood group O patients receiving significantly more fibrinogen concentrate.
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| 18. |
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| 19. |
- Himonakos, Christos, et al.
(författare)
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Long-term Follow-up of 84 Patients With Giant Prolactinomas-A Swedish Nationwide Study.
- 2023
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Ingår i: The Journal of clinical endocrinology and metabolism. - : Oxford University Press. - 1945-7197 .- 0021-972X. ; 108:12
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Tidskriftsartikel (refereegranskat)abstract
- To describe the clinical presentation and treatment outcomes in a nationwide cohort of patients with giant prolactinomas.Register-based study of patients with giant prolactinomas [serum prolactin (PRL) > 1000 µg/L, tumor diameter ≥40 mm] identified in the Swedish Pituitary Register 1991-2018.Eighty-four patients [mean age 47 (SD ±16) years, 89% men] were included in the study. At diagnosis, the median PRL was 6305 µg/L (range 1450-253 000), the median tumor diameter was 47 mm (range 40-85), 84% of the patients had hypogonadotropic hypogonadism, and 71% visual field defects. All patients were treated with a dopamine agonist (DA) at some point. Twenty-three (27%) received 1 or more additional therapies, including surgery (n = 19), radiotherapy (n = 6), other medical treatments (n = 4), and chemotherapy (n = 2). Ki-67 was ≥10% in 4/14 tumors. At the last follow-up [median 9 years (interquartile range (IQR) 4-15)], the median PRL was 12 µg/L (IQR 4-126), and the median tumor diameter was 22 mm (IQR 3-40). Normalized PRL was achieved in 55%, significant tumor reduction in 69%, and combined response (normalized PRL and significant tumor reduction) in 43%. In the primary DA-treated patients (n = 79), the reduction in PRL or tumor size after the first year predicted the combined response at the last follow-up (P < .001 and P = .012, respectively).DAs effectively reduced PRL and tumor size, but approximately 1 patient out of 4 needed multimodal treatment. Our results suggest that the response to DA after 1 year is useful for identifying patients who need more careful monitoring and, in some cases, additional treatment.
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| 20. |
- Holmgren, Kerstin, et al.
(författare)
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Impacts of climate warming on the long-term dynamics of key fish species in 24 lakes
- 2012
-
Ingår i: Hydrobiologia. - : Springer Science and Business Media LLC. - 0018-8158 .- 1573-5117. ; 694, s. 1-39
-
Forskningsöversikt (refereegranskat)abstract
- Fish play a key role in the trophic dynamics of lakes. With climate warming, complex changes in fish assemblage structure may be expected owing to direct effects of temperature and indirect effects operating through eutrophication, water level changes, stratification and salinisation. We reviewed published and new long-term (10-100 years) fish data series from 24 European lakes (area: 0.04-5,648 km(2); mean depth: 1-177 m; a north-south gradient from Sweden to Spain). Along with an annual temperature increase of about 0.15-0.3A degrees C per decade profound changes have occurred in either fish assemblage composition, body size and/or age structure during recent decades and a shift towards higher dominance of eurythermal species. These shifts have occurred despite a reduction in nutrient loading in many of the lakes that should have benefited the larger-sized individuals and the fish species typically inhabiting cold-water, low-nutrient lakes. The cold-stenothermic Arctic charr has been particularly affected and its abundance has decreased in the majority of the lakes where its presence was recorded. The harvest of cool-stenothermal brown trout has decreased substantially in two southern lakes. Vendace, whitefish and smelt show a different response depending on lake depth and latitude. Perch has apparently been stimulated in the north, with stronger year classes in warm years, but its abundance has declined in the southern Lake Maggiore, Italy. Where introduced, roach seems to take advantage of the higher temperature after years of low population densities. Eurythermal species such as common bream, pike-perch and/or shad are apparently on the increase in several of the lakes. The response of fish to the warming has been surprisingly strong and fast in recent decades, making them ideal sentinels for detecting and documenting climate-induced modifications of freshwater ecosystems.
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| 21. |
- Johansson, Malin, et al.
(författare)
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Late survival and heart failure after transcatheter aortic valve implantation.
- 2016
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Ingår i: Asian cardiovascular & thoracic annals. - : SAGE Publications. - 1816-5370 .- 0218-4923. ; 24:4, s. 318-325
-
Tidskriftsartikel (refereegranskat)abstract
- Short-term survival in patients undergoing transcatheter aortic valve implantation is favorable. Our aim was to evaluate late survival and composite clinical endpoints specified by the Valve Academic Research Consortium-2, including rehospitalization for congestive heart failure.
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| 22. |
- Karlsson, Martin, et al.
(författare)
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A national data collection framework for recreational fishing : in fisheries, sea and water management
- 2015
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Knowledge and valuation of ecosystem services are important components for reaching the governmental goals for improving the natural environments. Recreational fishing has more than one million practitioners nationwide.Knowledge about the fishers and their catches increases the ability to assess whether the ecosystem services are retained. In addition, it gives means for evaluating the actions for the conservation, restoration and sustainable use of oceans, lakes and rivers. Knowledge of recreational fishing is also needed in order to follow up the details in its environmental objectives relating to outdoor recreation, tourism industry and the governmental goals in the open-air policy. The EU’s common fisheries policy, the Swedish environmental policy and Swedish fisheries policy all emphasize that ecosystem-based management should be implemented. Thus, there are needs for knowledge of the ecosystems which are exploited by humans. Fish populations are important components of aquatic ecosystems, and are affected by the surrounding environment, while they themselves affect the structures of the aquatic food-webs. Fishes often have regulatory functions in the ecosystems, and thereby contribute to valuable ecosystem services in addition to the more obvious services as providing food and recreation for humans. Mostly issues regarding the impacts of fishing-related activities on fish populations have been focused on commercial fishing. A widespread and intensive commercial fishing may lead to the depletion of stocks or, at worst, a collapse of the fish populations; the fish population reaching such low levels that recovery may be difficult. In recent years the knowledge of the impact of recreational fishing on aquatic systems has increased, but still the effects of recreational fishing on ecosystem are relatively poorly studied, compared to commercial fisheries. For many, it may be difficult to accept that recreational fishing may affect fish populations; each fisher/angler favour just their own fisheries without bearing in mind that although the small influence from each individual fisherman may be small, it will be significant when many fishermen harvest from the same stock. Recreational fishing and its effects on the aquatic ecosystems are often neglected in fisheries science, mainly due to the lack of data to estimate recreational fishing harvest with a sufficient resolution to calculate the effort and landings of recreational fisheries. In this report, we try to give an overall picture of the fish species needing increased knowledge in order to get an estimate of harvest in recreational fisheries and thereby the effect on fish populations. Furthermore, we also try to give a picture of international studies and finally to give examples of methods concerning how and to what extent one may conduct studies in Sweden. Our proposal is largely based on combining different surveys in specific areas that we believe can be used to scale-up the results. We suggest data collation of recreational fishing is concentrated to areas with public waters, because in other water bodies the land owner has sovereignty under the law. The focus areas we point out are those already having some data collection, both in terms of recreational fishing and environmental monitoring / stock assessment and where there are non-fishing protective areas nearby. Collection of data should not be made in all areas at every year; three areas are suggested to become intensive areas (data collection every year) and the remaining areas data collection will take place every three years - on a rolling schedule. The sampling methods we recommend are national survey (i.e. mail and telephone surveys), recording of catches in fishing tourism, voluntary catch registration of individual anglers, collection of data from fishing competitions, on-site inventory of fishing effort (e.g. count fetter and trailers), inventory of catch per effort (e.g. by creel-surveys) and fish tagging studies. For the west coast we propose one focus area, Älgöfjorden. At the coasts of Bohuslän County and the northern part of Halland County the fishing pressure is high for lobster and crab and therefore a focus area should be established in this area. We suggest that data are collected by on-site visits for inventorying fishing effort (counting numbers of pots / buoys / fishing people), combined with catch registration can return an estimates on catch per effort, and this can then be applied to a larger area. Another potential focus area is the area around Torhamn (Blekinge) which, for example, is popular area recreational fishing for pike. Torhamn is one of three national reference areas for coastal fish monitoring on the East Coast and has been monitored since 2002. It is also desirable to study aspects of fishing mortality in recreational fisheries. To our knowledge, there are no national studies that have explored the effects of catch-and-release in natural environments over long periods of time. The Bråviken Bay is a relatively limited and well-defined area having considered high recreational fishing pressure, but large time series from fish monitoring programmes are lacking. This site will give good opportunities for studying pike, pikeperch and to some extent also sea trout, data collection is suggested to take place every third year. An adjacent area is Kvädöfjärden having fish monitoring time series from 1989. Closely situated to Kvädöfjärden is Licknevarpefjärden where fishing has been prohibited since 1970. Additional areas that are of interest to follow up with some regularity are Asköfjärden, Gålö and / or Lagnö in the Stockholm archipelago. In the future it might be fruitful to shift data collection intensity between Torhamn in Blekinge and an area in Stockholm archipelago. Such decision should be based on factors like where the most practical solutions / contact network can be found. In the Gulf of Bothnia angling with nets, traps and similar gears are relatively widespread. We suggest that Långvind Bay in Gävleborg County, is an area for the study of recreational fishing in a relatively sparsely populated county and is most likely typical for large parts of the Gulf of Bothnia. Data collection is suggested to take place every year. As for the Gulf of Bothnia the recreational fishery in the Bothnian Bay are mainly targeting the whitefish, sea trout and, to some extent also perch. By monitoring the recreational fisheries in Kinnbäcksfjärden near Piteå, we hope to be able to describe the local recreational fishing patterns and then apply these values for catch per effort for most of the coastal strip of the Bothnian Bays. Recreational fishing is widespread in all of the five largest lakes in Sweden, and there is a need for data collection in all five. In Lake Vänern, Lake Vättern and Lake Mälaren there are fish monitoring data of good quality and regularity. However, in the two smallest lakes, Lake Hjälmaren and Lake Storsjön in Jämtland County, few test fishing areas and few studies regarding recreational fishing have been made. For Lake Vättern we suggest that data collection is done every year; especially the archipelago in the northern part of the lake will be an excellent area for the study of recreational fishing for pike. In the other four lakes we propose that data collection is made every third year. By studying recreational fishing - its practitioners, scope, gear-use, and harvest, it will be possible to achieve a more detailed view of how recreational fishing is done and how it varies along the Swedish coast and in the five largest lakes. Such knowledge is important for the managers of common fisheries resources and the monitoring of environmental status and evaluating the recreational goals established by the Swedish governments.
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| 23. |
- Karlsson, Martin, et al.
(författare)
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Nationell plan för kunskapsförsörjning om fritidsfiske inom fisk-, havs- och vattenförvaltningen
- 2014
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- I följande rapport försöker vi ge en samlad bild för vilka arter som är i behov av ett utökat kunskapsunderlag med avseende på fritidsfiskets uttag och påverkan. Vidare försöker vi ge en bild av hur man internationellt arbetar med liknande frågor och ger slutligen exempel på metoder på hur och i vilket utsträckning man kan arbeta på ett nationellt plan. Vårt förslag grundar sig i stort på att man kombinerar olika undersökningar i särskilda fokusområden som vi bedömer kan användas för att skala upp resultaten från. Vi föreslår att man koncentrerar insamlingen av fritidsfiskedata till områden med allmänt vatten, eftersom i enskilda vatten har fiskevattenägaren överhöghet enligt lagstiftningen. De fokusområden vi pekar ut är sådan där det redan bedrivs viss datainsamling, både vad gäller fritidsfiske och miljöövervakning/bestånduppskattning och där det finns fiskefria områden i närheten. Insamling av data ska inte ske i alla områden varje år, tre områden förslå bli intensivområden och i övriga ska insamling ske vart tredje år efter ett rullande schema. De insamlingsmetoder som vi förspråkar är nationell enkät, fångstregristrering inom fisketurismen, frivillig fångstregistrering av enskilda fritidsfiskare, insamling av data från fisketävlingar, inventering av fiskeansträngning (t.ex. räkna boja och trailers) på plats, inventering av fångst per ansträngning (t.ex. genom provfisken) och märkningsstudier.
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| 24. |
- Langenheder, Silke, et al.
(författare)
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The role of environmental and spatial factors for the composition of aquatic bacterial communities
- 2007
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Ingår i: Ecology. - : Wiley. - 0012-9658 .- 1939-9170. ; 88:9, s. 2154-2161
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Tidskriftsartikel (refereegranskat)abstract
- This study investigates the importance of local vs. spatial factors on bacterial community composition of 35 rock pools at the Baltic Sea coast. The pools were located in five distinct spatial clusters over a total scale of <500 m and differed widely in terms of water chemistry. To determine the fractions of the variance in bacterial community composition (BCC) between rock pools that are explained by local environmental vs. spatial factors, a variance partitioning procedure using partial canonical correspondence analysis was performed. Three environmental variables (salinity, chlorophyll a concentration, and water color) had a significant effect on BCC, irrespective of the spatial location of the pools. Vice versa, there was a significant effect of spatial factors on BCC irrespective of any of the environmental factors included in this study. Hence, the patchy spatial distribution of the pools was partly reflected in the composition of the bacterial communities in the pools, which might be caused by congruent colonization events of adjacent pools, such as simultaneous sea-spray inputs or direct exchange of bacteria via connecting rivulets. This study shows that the composition of planktonic bacteria can show provincialism at small spatial scales, which is likely to be caused by -environmental conditions as well as historical events.
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| 25. |
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| 26. |
- Novén, Johan, et al.
(författare)
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Exercise Echocardiography following Septal Myectomy for Hypertrophic Obstructive Cardiomyopathy
- 2022
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Ingår i: The Thoracic and Cardiovascular Surgeon. - : Georg Thieme Verlag KG. - 0171-6425 .- 1439-1902. ; 70:1, s. 18-25
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Tidskriftsartikel (refereegranskat)abstract
- Objectives To investigate outcome after septal myectomy and to evaluate long-term hemodynamics with exercise echocardiography. Methods This study included 40 consecutive patients operated with septal myectomy for hypertrophic obstructive cardiomyopathy from January 1998 to August 2017 at Skane University Hospital, Lund, Sweden. Perioperative clinical data and echocardiography measurements were reviewed retrospectively. Patients (n = 36) who were alive and living in Sweden were invited for exercise echocardiography to evaluate exercise capacity and hemodynamics, of whom 19 patients performed exercise echocardiography. Results Overall survival was 100% at 1 year and 96% at 5 years following surgery. Preoperative median resting peak LVOT (left ventricular outflow tract) gradient was 80 mm Hg. Septum thickness was reduced from 22 ± 4 mm preoperatively to 16 ± 3 mm postoperatively (p < 0.001). During exercise echocardiography, the peak LVOT gradient was 8 mm Hg at rest, and increased to 13 mm Hg during exercise echocardiography (p = 0.002). None of the patients had dynamic LVOT obstruction during exercise echocardiography, and there was no clinically significant systolic anterior motion or severe mitral insufficiency during exercise. Conclusions Long-term survival following septal myectomy is very good. At long-term follow-up, LVOT gradients were low and exercise echocardiography demonstrated good hemodynamics.
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| 27. |
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| 28. |
- Petersson, M., et al.
(författare)
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Natural history and surgical outcome of Rathke's cleft cysts-A study from the Swedish Pituitary Registry
- 2022
-
Ingår i: Clinical Endocrinology. - : Wiley. - 0300-0664 .- 1365-2265. ; 96:1, s. 54-61
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Tidskriftsartikel (refereegranskat)abstract
- Objective Rathke's cleft cysts are benign, embryological remnants in the pituitary gland. The majority of them are small and asymptomatic but a few may become large, and cause mass effects, pituitary hormone deficiencies and visual impairment. Recommendations for the follow-up of Rathke's cleft cysts vary since data on the natural history are sparse. Patients and Design Data at diagnosis and at 1, 5 and 10 years for patients with a Rathke's cleft cyst (434 at diagnosis, 317 females) were retrieved from the Swedish Pituitary Registry. Cysts <= 3 mm in diameter were excluded from the study. Measurements Data included demographics, cyst size, pituitary function, visual defects and surgery. Results The mean age at diagnosis was 45 years. In patients with cysts <10 mm in diameter (n = 204) 2.9% had pituitary hormone deficiencies and 2% had visual field impairments. Cyst size did not progress during the 5 years. Cysts with a diameter of >= 10 mm that were not operated (n = 174) decreased in size over the years (p < .01). Pituitary hormone deficiencies and visual impairments were more frequent (18% and 5.7%, respectively) but were stable over time. Transphenoidal surgery was performed in 56 patients of whom 51 underwent surgery before the 1-year follow-up. The mean cyst diameter at diagnosis was 18 mm (range: 930 mm), 36% had pituitary hormone deficiency, 45% had visual field defects and 20% had impaired visual acuity. One year after surgery 60% had no cyst remnants, 50% had a pituitary deficiency, 26% had visual field defects and 12% had impaired visual acuity. No major changes were observed after 5 years. Twelve of the operated patients had a follow-up at 10 years, in eight the cyst remnants or recurrences increased in size over time (p < .05). Conclusions Rathke's cleft cysts with a size less than 10 mm rarely grow and our results indicate that radiological follow-up can be restricted to 5 years. In contrast, progression of postoperative remnants or recurrent cysts is more likely and require long-term follow-up.
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| 29. |
- Ragnarsson, Charlotte, et al.
(författare)
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Constitutional and acquired genetic variants in ARID5B in pediatric B-cell precursor acute lymphoblastic leukemia
- 2024
-
Ingår i: Genes Chromosomes and Cancer. - 1045-2257. ; 63:5
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Tidskriftsartikel (refereegranskat)abstract
- Constitutional polymorphisms in ARID5B are associated with an increased risk of developing high hyperdiploid (HeH; 51–67 chromosomes) pediatric B-cell precursor acute lymphoblastic leukemia (BCP ALL). Here, we investigated constitutional and somatic ARID5B variants in 1335 BCP ALL cases from five different cohorts, with a particular focus on HeH cases. In 353 HeH ALL that were heterozygous for risk alleles and trisomic for chromosome 10, where ARID5B is located, a significantly higher proportion of risk allele duplication was seen for the SNPs rs7090445 (p = 0.009), rs7089424 (p = 0.005), rs7073837 (p = 0.03), and rs10740055 (p = 0.04). Somatic ARID5B deletions were seen in 16/1335 cases (1.2%), being more common in HeH than in other genetic subtypes (2.2% vs. 0.4%; p = 0.002). The expression of ARID5B in HeH cases with genomic deletions was reduced, consistent with a functional role in leukemogenesis. Whole-genome sequencing and RNA-sequencing in HeH revealed additional somatic events involving ARID5B, resulting in a total frequency of 3.6% of HeH cases displaying a somatic ARID5B aberration. Overall, our results show that both constitutional and somatic events in ARID5B are involved in the leukemogenesis of pediatric BCP ALL, particularly in the HeH subtype.
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| 30. |
- Ragnarsson, Henrik, 1976-
(författare)
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Biological Diversity of Fish and Bacteria in Space and Time
- 2008
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Biological diversity is controlled by an array of factors and processes all active at different spatial and temporal scales. Regional factors control what species are available to occur locally, whereas the local factors determine what species are actually capable of colonizing the locality.I have investigated how these local and regional factors affect species richness and diversity, mainly of fish in Swedish lakes and in order to assess the impact of dispersal mode one study on bacteria was also performed. In addition, potential first steps towards speciation were investigated in perch (Perca fluviatilis) from two different habitats.Fish species richness and diversity were found to be regulated by history, dispersal limitation and the local environment. In addition, striking similarities were found in the control of community composition for fish and bacteria. Both were regulated by nearly equal parts regional and local factors. The study of morphological and genetical variation in perch (Perca fluviatilis) revealed genetic differentiation at small spatial scales, suggesting that genetic differences can evolve between groups at strikingly small spatial scales, which might have implications for speciation in a long time perspective.Based on these findings I conclude that space and time matter. Space has the potential to isolate sites. And both dispersal and local extinctions, it seems, might take a long time, as effects of the last ice-age can still be seen on the contemporary fish community richness and composition.
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| 31. |
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| 32. |
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| 33. |
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| 34. |
- Ragnarsson, Oskar, 1971, et al.
(författare)
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A clinical perspective on ectopic Cushing's syndrome
- 2024
-
Ingår i: Trends in Endocrinology and Metabolism. - 1043-2760 .- 1879-3061. ; 35:4, s. 347-360
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Forskningsöversikt (refereegranskat)abstract
- Cushing's syndrome (CS) refers to the clinical features of prolonged pathological glucocorticoid excess. About 10–20% of individuals with CS have ectopic CS (ECS), that is, an adrenocorticotropin (ACTH)-producing tumour outside the pituitary gland. ACTH-secreting neuroendocrine neoplasia (NENs) can arise from many organs, although bronchial NEN, small cell lung cancer (SCLC), pancreatic NEN, thymic NEN, medullary thyroid cancer (MTC), and pheochromocytoma are the most common. Patients with ECS frequently present with severe hypercortisolism. The risk of life-threatening complications is high in severe cases, unless the hypercortisolism is effectively treated. A good outcome in ECS requires a methodical approach, incorporating prompt diagnosis, tumour localization, control of cortisol excess, and resection of the primary tumour when possible.
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| 35. |
- Ragnarsson, Oskar, 1971, et al.
(författare)
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Neurodegenerative and inflammatory biomarkers in cerebrospinal fluid in patients with Cushing's syndrome in remission.
- 2013
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Ingår i: European journal of endocrinology / European Federation of Endocrine Societies. - 1479-683X. ; 169:2, s. 211-5
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Tidskriftsartikel (refereegranskat)abstract
- Patients with Cushing's syndrome (CS) in long-term remission have impaired cognitive function. Cerebrospinal fluid (CSF) biomarkers are important diagnostic tools in the work-up of patients with cognitive impairment. The aim of this study was to analyze neurodegenerative and inflammatory biomarkers in the CSF of patients with CS in remission.
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| 36. |
- Ragnarsson, Sigurdur, et al.
(författare)
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No-touch saphenous vein grafts in coronary artery surgery (SWEDEGRAFT): Rationale and design of a multicenter, prospective, registry-based randomized clinical trial
- 2020
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Ingår i: American Heart Journal. - : MOSBY-ELSEVIER. - 0002-8703 .- 1097-6744. ; 224, s. 17-24
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Tidskriftsartikel (refereegranskat)abstract
- The SWEDEGRAFT study (ClinicalTrials.gov Identifier: NCT03501303) tests the hypothesis that saphenous vein grafts (SVGs) harvested with the "no-touch" technique improves patency of coronary artery bypass grafts compared with the conventional open skeletonized technique. This article describes the rationale and design of the randomized trial and baseline characteristics of the population enrolled during the first 9 months of enrollment. The SWEDEGRAFT study is a prospective, binational multicenter, open-label, registry-based trial in patients undergoing first isolated nonemergent coronary artery bypass grafting (CABG), randomized 1:1 to no-touch or conventional open skeletonized vein harvesting technique, with a planned enrollment of 900 patients. The primary end point is the proportion of patients with graft failure defined as SVGs occluded or stenosed >50% on coronary computed tomography angiography at 2 years after CABG, earlier clinically driven coronary angiography demonstrating an occluded or stenosed >50% vein graft, or death within 2 years. High-quality health registries and coronary computed tomography angiography are used to assess the primary end point. The secondary end points include wound healing in the vein graft sites and the composite outcome of major adverse cardiac events during the first 2 years based on registry data. Demographics of the first 200 patients enrolled in the trial and other CABG patients operated in Sweden during the same time period are comparable when the exclusion criteria are taken into consideration.
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| 37. |
- Ragnarsson Stabo, Henrik, et al.
(författare)
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Can multi-frequency acoustics improve the monitoring of large zooplankton in large temperate lakes?
- 2014
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Ingår i: Aquatic Ecosystem Health and Management. - : Michigan State University Press. - 1463-4988 .- 1539-4077. ; 17, s. 374-381
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Tidskriftsartikel (refereegranskat)abstract
- Large zooplankton has an important role for the functioning of the ecosystem in many lakes. Most are predatory, which makes them both competitors as well as food for many planktivorous fish species. In general, it has been elusive to measure the abundance of this group of zooplankton with traditional sampling methods, particularly in large volumes of water. In this study we tested the potential and adequacy of multi-frequency hydroacoustics as a method to map the spatial patterns in abundance of the large zooplankton in Lake Vanern, Lake Vattern and Lake Malaren. In addition, we used a plankton net to groundtruth biovolume estimates vertically, and a Tucker trawl for the horizontal distribution. Two frequencies were used to separate the acoustic backscattering from fish, mysids and plankton. The main target species were Leptodora kindtii, Bythotrephes longimanus and Limnocalanus macrurus.The plankton communities were very heterogeneous both within and among the lakes. Lake Vanern and Lake Malaren were dominated by Leptodora, whereas Lake Vattern was dominated by Limnocalanus. Bottom depth at the sample site was the most important community structuring factor.Our results indicate that the biomass of large predatory zooplankton is comparably high and in most surveyed areas even higher than the biomass of planktivorous fish. Consequently, they are more important for the dynamics of lake food webs than previously assumed. Using multi-frequency hydroacoustics show promising results and with some alterations to the sampling design this would be a valuable addition to the traditional zooplankton monitoring in large lakes.
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| 38. |
- Ragnarsson Stabo, Henrik
(författare)
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Drömfisk vid regnbågens slut
- 2011
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Ingår i: Fiskejournalen. ; , s. 64-68
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 39. |
- Ragnarsson Stabo, Henrik, et al.
(författare)
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Fiskfångster och utsättning av fisk
- 2011
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Ingår i: Vänern - Årsskrift 2011. ; :66, s. 61-66
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 40. |
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| 41. |
- Ragnarsson Stabo, Henrik, et al.
(författare)
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Kvantifiering av stora djurplankton i de stora sjöarna
- 2012
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Ingår i: Rapport - Vänerns vattenvårdsförbund. - 1403-6134. ; , s. 89-106
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Large zooplankton (>2 mm) are important for the functioning of the ecosystem in many large lakes. In several cases they have severely altered the food web where they have invaded. Most are predatory, which makes them both direct competitors to, and the dominant food of, many planktivorous fish species. In addition, juveniles of several predatory species, such as zander (Sander lucioperca) have been reported to utilize them extensively. In this case study we used different methods to map the spatial patterns in abundance of the large zooplankton in Lake Vänern, Lake Vättern and Lake Mälaren. The cladocerans Leptodora kindtii and Bythotrephes longimanus are predators whereas the copepod Limnocalanus macrurus is an omnivore. Generally, quantitative measurements of large zooplankton in large volumes of water are difficult to obtain with traditional sampling methods. In this case study we sampled plankton with a large plankton net - to obtain biovolume estimates horizontally, and with a tucker trawl for the vertical distribution[TA1]. A total of 58 samples were collected. In addition, multi-frequency hydroacoustics was tested as a monitoring method, with the tucker trawls as ground truth. Two frequencies were used to separate the acoustic backscattering from fish, mysids and plankton. The plankton communities were very heterogenous both within and among the lakes. Both Lake Vänern and Lake Mälaren were dominated by Leptodora, whereas Lake Vättern was dominated by Limnocalanus. The depth at the sample site was most important for the structure of the community, with Limnocalanus predominantly present below the thermocline. The hydroacoustics showed some potential for sampling the species that do not share habitat with mysids. The high densities of predatory zooplankton found in all lakes indicate that they have the potential of being important prey species for fish as well as competitors, and thus any ecosystem models in these lakes should include them. Our results indicate that large predatory zooplankton are found in the same amount (biomass) as planktivorous fish. Consequently, they are important in the food web of all three lakes. Hydroacoustic monitoring of some of the species show promising results and with some alterations in the sampling methods this could be a useful addition to the regular zooplankton monitoring of the large lakes.
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| 42. |
- Ragnarsson Stabo, Henrik, et al.
(författare)
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Kvantifiering av stora djurplankton i de stora sjöarna
- 2012
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Stora djurplankton (>2 mm) fyller en viktig funktion i många sjöekosystem. De flesta är rovdjur, vilket leder till att de är både konkurrenter och föda till många planktonätande fiskar. Dessa storväxta planktonarter kan också utgöra viktig föda för unga rovfiskar, t.ex. gös (Sander lucioperca). I denna studie testades olika metoder för att kartlägga och kvantifiera förekomsten av stora djurplankton i Vänern, Vättern och Mälaren. Det har visat sig att den traditionella provtagningen ofta missar de stora djurplantonarterna. Här testade vi en stor och grovmaskig planktonhåv för att få ett mått på biomassorna av plankton per ytenhet. Tuckertrål kombinerat med hydroakustik användes för att få ett mått på arternas vertikalfördelning och rumsliga fördelning. Flera frekvenser användes för att skilja på den detekterade energin från fisk och djurplankton som vid ekolodning reflekteras från organismerna. Totalt samlades 58 håv- och trålprover in. Planktonsamhället varierade starkt både mellan och inom sjöar. Vänern och Mälaren dominerades av Leptodora, medan Vättern dominerades av Limnocalanus. Djupet var avgörande för vilka arter som förekom i proverna, speciellt tydligt var det hos Limnocalanus som främst förekom i det kalla vattnet under språngskiktet. Hydroakustisk visade sig vara en möjlig metod för att mäta mängden stora djurplankton i de stora sjöarna. Mysider har tidigare visats ge starka och urskiljningsbara signaler i Vättern. Vår undersökning visade att även tofsmygglarver (Chaoborus) gav mycket starka signaler, som riskerar att överskugga de svagare signalerna från djurplankton. Vi föreslår därför att eventuell framtida hydroakustisk övervakning ska ske i dagsljus då både mysider och tofsmygglarver håller sig nära eller på botten. Våra resultat visar att biomassan stora djurplankton per ytenhet är i samma storleksordning som mängden fisk. Det indikerar att de är viktiga i födoväven och bör övervakas. Hydroakustik kombinerad med håvning eller Tucker-trålning skulle utgöra ett värdefullt komplement till den vanliga djurplanktonprovtagningen.
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| 43. |
- Ragnarsson Stabo, Henrik
(författare)
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Recreational fishing for carp—implications for management and growth of carp populations
- 2015
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Ingår i: Biology and Ecology of Carp. - : CRC Press. - 9781482206647 ; , s. 282-298
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Bokkapitel (refereegranskat)abstract
- Few fish species give rise to as conflicting opinions as carp. On the one hand, carp are often considered an invasive species and a pest. On the other hand, many consider carp the most desirable species on the planet, and devote their lives to catching them. Carp fishing is increasing in popularity and also the demand for carp fisheries, for example more than 1.9 million carp were stocked in England and Wales in 2002–2003 (Environment agency 2004). In Europe, carp fishing has a high socioeconomic value (e.g., Arlinghaus and Mehner 2003). In England and Wales alone, 26 million days were spent coarse angling. The angler gross expenditure was in excess of 1 billion euro and 30,000 jobs were generated (Radford et al. 2007). Considering the increasing demand for carp fishing, it is important that there are guidelines for managing carp lakes sustainably without jeopardizing the ecosystems of these lakes. Here the attraction of carp to anglers, especially emphasizing growth rates and biomasses of carp in nature and how to combine carp fishing and healthy lakes are explored.
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| 44. |
- Sandström, Alfred, et al.
(författare)
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A test of sampling methods for fishes in the littoral zone of Lake Vanern, Sweden
- 2014
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Ingår i: Aquatic Ecosystem Health and Management. - : Michigan State University Press. - 1463-4988 .- 1539-4077. ; 17, s. 357–364-
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Tidskriftsartikel (refereegranskat)abstract
- Shallow, vegetated habitats play an important role as spawning and nursery areas for several species of fish. Such habitats are often laborious to monitor with conventional sampling methods. We evaluated two quantitative methods for sampling of young fishes in shallow habitats; point abundance with electrofishing and low-impact pressure wave sampling using small underwater detonations. The study was conducted in the littoral zone of an archipelago area in Lake Vanern, Sweden. Both methods rendered quantitative estimates on the most common fish species. However, underwater detonations yielded more species and lower variation among samples. These differences are likely due to the larger sample area of detonations. Species distribution and juvenile fish density estimates and size-structure were compared with results from multi-mesh gill nets. The dominant fish species in the gill net program were recorded with both active methods although the relative composition differed, mainly as a consequence of differences in species and size selectivity. Detonations provided additional, small-bodied, species that were not recorded in the gill net program. Quantitative methods can provide relevant information for identifying essential fish habitats, understanding ecosystem dynamics and providing a baseline for assessing long-term changes (e.g. due to climate change or new water level regimes) in Lake Vanern.
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| 45. |
- Sandström, Alfred, et al.
(författare)
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Assessing the potential of remote sensing-derived water quality data to explain variations in fish assemblages and to support fish status assessments in large lakes
- 2016
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Ingår i: Hydrobiologia. - : Springer Science and Business Media LLC. - 0018-8158 .- 1573-5117. ; 780, s. 71-84
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Tidskriftsartikel (refereegranskat)abstract
- Remote sensing techniques may provide a higher temporal and spatial resolution than traditional water monitoring methods. We tested if this auxiliary information can be used to (i) explain patterns in fish assemblage composition and (ii) test candidate metrics to assess ecological status in large lake water bodies. We used MERIS-derived layers describing chlorophyll a, total suspended matter, and colored dissolved organic matter (CDOM) overlaid on all available fish monitoring data from the four largest Swedish lakes (Vanern, Vattern, Malaren, and Hjalmaren). We assessed the influence of remote sensing-derived parameters in the pelagic, offshore benthic, and the inshore benthic habitats. Our results demonstrated that chlorophyll a and CDOM together with depth at the sampling site explained a significant part of the variation in the distribution of fish assemblages. These predictors were particularly important not only in pelagic, but also in inshore benthic areas. Furthermore, we identified three potential candidate metrics to assess pressure from eutrophication in large lakes: density of pelagic fishes, biomass of planktivorous species, and the proportion of cyprinids when roach was excluded. Remote sensing was considered a useful tool to support analyses of fish community composition and dynamics.
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| 46. |
- Sandström, Alfred, et al.
(författare)
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Collaborative research enhances selectivity in a lake fishery
- 2024
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Ingår i: Fisheries Management and Ecology. - : John Wiley & Sons. - 0969-997X .- 1365-2400.
-
Tidskriftsartikel (refereegranskat)abstract
- Size and species selectivity are crucial for developing sustainable fisheries. Our objective was to estimate the selectivity of whitefish fisheries in a large European lake through a collaboration of fishers, regional managers, and scientists. Fishers were given special permits to test, within a common framework and together with scientists, selectivity enhancement strategies adapted to their own experiences. Fishers and scientists jointly tested gillnets and pontoon traps and how fishing depth, soak time, fishing season, and mesh size were affected by bycatches of undersized fish of sensitive species. Results indicated that the selectivity of the fishery could be increased, particularly by targeting whitefish adjacent to spawning sites where spatiotemporal overlap with bycatch species was lower. Proposed changes to the fishery, such as new gear, would be costly initially but could become profitable over time due to a lower cost of handling bycatch. Our findings demonstrated that co-constructed knowledge can contribute to the governance of aquatic resources.
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| 47. |
- Sandström, Alfred, et al.
(författare)
-
Fiskefredning i sjöar : I vilken mån används fredningsområden för fiske i Sveriges 205 största sjöar?
- 2016
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Fiskar är, ur ett globalt perspektiv, en av de allra mest kritiskt hotade djurgrupperna. En metod som föreslagits för att skydda hotade fiskarter och bestånd är att införa olika typer av fredningsområden som begränsar fisket i vissa delar av ett vatten. Förutom totalt fiskeförbud året om, kan det röra sig om tidsbegränsad fredning eller att en viss fiskemetod är förbjuden inom ett område. En angränsande förvaltningsåtgärd är när fredning införs för att garantera ett långsiktigt naturskydd av fiskens mest värdefulla habitat. Naturskydd innebär dock endast i undantagsfall (t.ex. i flertalet Nationalparker) att man inför begränsningar i fisket. I marina miljöer har fredningsområden (så kallades MPA:s) debatterats under en längre tid. I sötvatten har de dock inte alls fått samma fokus trots att behoven är snarlika. Syftet med denna studie har varit att kartlägga fiskeregler och då särskilt användningen av fredningsområden i 205 stora svenska sjöar. Först kartlades fiskereglerna i de av staten reglerade Vänern, Vättern, Mälaren, Hjälmaren och Jämtländska Storsjön. Därefter genomfördes en omfattande enkätundersökning riktad till de organisationer som är aktiva i förvaltningen av fisket i ytterligare 200 stora svenska sjöar jämnt spridda över landet. Enkätstudien innehöll förutom frågor om användningen av fredningsområden också frågor om övriga fiskeregler. I två av de fem största sjöarna användes fredningsområden som förvaltningsinstrument (Vänern och Vättern). Det var dock endast i Vättern som fredningsområden kan anses vara en integrerad och betydelsefull del av förvaltningen. Av de 63 % som svarade i enkätundersökningen riktad till angav cirka 50 % att det fanns någon form av fredningsområden i deras sjöar. De flesta fredade områden fanns i tillrinnande vattendrag och deras mynningsområden i sjöarna. Följaktligen var öring (Salmo trutta, L.) också den fiskart som var mål för en majoritet av de fredade områdena. Endast i mycket enstaka fall fanns områden i själva sjöarna med totalt fiskeförbud som varade året runt. Fredningsområden i sjöarna var vanligtvis relativt små. I de sjöar där sådana fanns täckte de i genomsnitt 1,6 % av sjöytan. Vår bedömning är att många av de befintliga fredningsområdena är för små för att få en långsiktig effekt på fiskedödligheten särskilt för mer rörliga arter. Förutom fredningsområden var olika typer av begränsningar av fångststorleken (minimimått, maximimått och storleksfönster) mycket vanligt förekommande. Resultaten från studien visar att fredningsområden visserligen används både på enskilda och allmänna vatten men att det finns en stor potential att utveckla deras användning och anpassa utformningen så att de kan bidra till uppställda förvaltningsmål. I takt med att GIS-baserade instrument och andra digitala verktyg utvecklas, förbättras möjligheten att arbeta med lokalisering och design av hela nätverk av skyddade områden (inom sjöar och kanske även inom hela avrinningsområden) på helt nya sätt. Vi hoppas att utvecklingen kommer gå mot att man inom det allmänna arbetet med habitat- och naturvärdesskydd kommer att ta större hänsyn till fiskefrågor och att fredningsområden för fiske blir mer integrerade i övrigt naturskydd.
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| 48. |
- Sandström, Alfred, et al.
(författare)
-
Fiskets fångster och trender för Vätterns kommersiella fisk- och kräftarter
- 2015
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Ingår i: Rapport nr 119 från Vätternvårdsförbundet. ; :27, s. 119-132
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Bokkapitel (populärvet., debatt m.m.)abstract
- Vättern har en av Sveriges och även Europas allra längsta tidsserier med fiskestatistik. Ända se-dan 1914 har fångsterna i det yrkesmässiga fisket registrerats. Fiskets inriktning har förändrats markant under senare år. Tidigare riktades fisket mot sik och röding, numera är det istället signal-kräfta som är den viktigaste arten för fisket. Efter tre år med vikande fångster har fångsten åter ökat de två senaste åren och år 2013 var kräftfångsten cirka 107 ton. Signalkräftan står därmed fortfarande för merparten av värdet i fisket, drygt 90 % av intäkterna i första handelsled. De sen-aste tre åren har det dock skett ett visst trendbrott med ökade fångster av främst röding, öring, sik och lake. För flertalet arter är numera fritidsfiskets fångster relativt omfattande och i vissa fall sannolikt större än i yrkesfisket. Om man summerar de skattade fångsterna i fritidsfisket med de som sker i yrkesfisket så är det tydligt att de totala fångsterna av många arter ökat på senare år. Särskilt för röding, öring, lake och sik är fångsttrenden positiv. Under året har bestånden överva-kats med bottensatta provfiskenät. Resultaten visar att beståndet av sik är fortsatt starkt. Fångsten av sik var den högsta hittills under de tio år som provfisken bedrivits. De flesta fiskätande arter fortsätter också att öka, särskilt tydliga positiva trender finns för röding och öring men även för lake.
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| 49. |
- Sandström, Alfred, et al.
(författare)
-
Fiskets fångster och trender för Vätterns kommersiella fiskarter.
- 2012
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Ingår i: Årsskrift 2012 : Rapport nr 116 från Vätternvårdsförbundet. ; 116:116, s. 76-88
-
Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Vättern har en av Sveriges och även Europas allra längsta tidsserier med fiskestatistik. Ända sedan 1914 har fångsterna i det yrkesmässiga fisket registrerats. Fiskets inriktning har förändrats markant under senare år. Tidigare riktades fisket mot sik och röding, numera är det istället signalkräfta som är den viktigaste arten för fisket. År 2010 minskade visserligen fångsten av kräftor till 94 ton, en minskning med cirka 20 %. Trots detta stod signalkräftan för cirka 95 % av intäkterna i fisket. Fångsterna av andra arter än kräftor har varit låga och relativt stabila de senaste åren. Under året publicerades en utredning och analys av fritidsfiskets fångster, statistik som tidigare inte funnits tillgängliga. Resultaten verifierar att fritidsfisket är relativt omfattande och att fångsterna är större än i yrkesfisket för de populäraste arterna. Om man summerar de skattade fångsterna i fritidsfisket med övriga fisken så är det tydligt att fångsterna av många arter ökat på senare år. Särskilt för röding, öring och sik är trenden positiv mellan åren 2003 och 2011. Under året har också fortsatta ansträngningar gjorts med bottensatta provfiskenät. Resultaten visar att beståndet av sik fortfarande är talrikt och stabilt samt att de flesta fiskätande arter som t. ex. röding, öring, lake och abborre fortsätter att öka.
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| 50. |
- Sandström, Alfred, et al.
(författare)
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Fiskfångster och utsättningar av fisk
- 2014
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Ingår i: Årsskrift 2014. ; :84, s. 77-83
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Bokkapitel (övrigt vetenskapligt/konstnärligt)abstract
- Totalfångsten i yrkesfisket i Vänern var oförändrad jämfört med 2012. Den viktigaste arten för yrkesfisket var gös, vilken stod för cirka 38 % av totala fångstens värde. Den näst viktigaste arten är siklöja (35 % av värdet). Fångsten av övriga viktiga arter som gädda, gös, lax, signalkräfta, öring och ål var på samma nivå som 2012. Fångsten av abborre minskade från 41 till 33 ton. De registrerade fritidsfiskarna fångade under 2013 totalt 69 ton, vilket är ungefär på samma nivå som 2012 men en minskning sett över längre tid. Totalt 267 276 smolt sattes ut vilket är över medelvärdet för den föregående femårsperioden. Även utsättningen av ål har ökat på senare år, 600 000 försträckta alternativt karantäniserade ålyngel sattes ut under både 2013 och 2014.
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