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- Gillberg, Christopher, 1950, et al.
(författare)
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Bengt Hagberg.
- 2015
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Ingår i: Acta paediatrica (Oslo, Norway : 1992). - : Wiley. - 1651-2227 .- 0803-5253. ; 104:10
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 6. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Co-existing disorders in ADHD -- implications for diagnosis and intervention.
- 2004
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Ingår i: European Child & Adolescent Psychiatry. - : Springer Science and Business Media LLC. - 1018-8827 .- 1435-165X. ; 13 Suppl 1
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: It is only recently that "comorbidity" in ADHD has come to the forefront as one of the most important aspects of the disorder. It is agreed that, often, these problems are at least as important as ADHD in contributing to the longer term outcome in the individual child. OBJECTIVE: To provide the reader with basic information about clinics and treatment of "comorbidity" in ADHD. METHOD: Review of the empirically based literature. RESULTS: ADHD exists in a surprisingly high frequency together with a broad range of child neuropsychiatric disorders. This is accompanied with many still unresolved treatment problems. CONCLUSION: It would not be appropriate to develop ADHD-services where clinicians would only have expertise in ADHD as such. Anyone working with children, adolescents and adults with ADHD would need to have training in general neuropsychiatry. Further research in this field is urgently needed.
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| 8. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Handedness in Swedish 10-year-olds. Some background and associated factors.
- 1984
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Ingår i: Journal of Child Psychology and Psychiatry, and Allied Disciplines. - 0021-9630. ; 25:3, s. 421-432
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Tidskriftsartikel (refereegranskat)abstract
- Forty-five left-handed and 46 right-handed 10-year-old children were subjected to a limited set of neurological tests and a square tracing task. 'Pathological' handedness was diagnosed in cases showing poor performance with the non-preferred hand on the squares task. The frequency of left-handedness in the population was estimated at 9.2%. The boy : girl ratio was 1.6:1. 'Pathological' handedness was twice as common among left-handers as among right-handers. Neurological dysfunction was more common in 'pathological' handers, especially left-handers. Reduced pre-. peri- and neonatal optimality was seen in boys with 'pathological handedness'. School achievement problems and behaviour problems were much more common in left-handed boys than in other study groups. The results lend partial support for the extended pathological left-handedness model recently hypothesized by Bishop, but it is suggested that left-handedness in boys is more often a symptom of pathological shift of handedness than is left-handedness in girls.
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| 10. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Hyperkinetic disorders in seven-year-old children with perceptual, motor and attentional deficits.
- 1983
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Ingår i: Journal of Child Psychology and Psychiatry, and Allied Disciplines. - 0021-9630. ; 24:2, s. 233-246
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Tidskriftsartikel (refereegranskat)abstract
- One hundred and forty-one seven-year-old Swedish children took part in an extensive neuropsychiatric study involving total population samples of children who had shown perceptual, motor and attentional deficits in pre-school, and blindly examined comparison children. The present paper reports on generalized hyperkinesis, i.e. hyperactivity in the child in all of three different assessment settings. About a third of children diagnosed according to strict criteria as suffering from 'Minimal Brain Dysfunction' showed generalized hyperkinesis. In children without perceptual-motor deficits, hyperkinesis was very much rarer. A total population frequency for generalized hyperkinesis in the range of 1-3% is reported as probable. Heredity for delayed maturation, non-optimal pre-, peri- and neonatal factors and adverse psychosocial factors were found to interact in the shaping of the disorder.
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| 11. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Long-term follow-up of children born after amniocentesis.
- 1982
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Ingår i: Clinical Genetics. - 0009-9163. ; 21:1, s. 69-73
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Tidskriftsartikel (refereegranskat)abstract
- Paediatric and neurodevelopmental examinations were made of 122 children between the ages of 5 and 7 years. The mothers of 62 of these children had undergone amniocentesis for prenatal chromosome determination. The other 60 children were controls, matched for time of birth and maternal age. The fact that no difference between the groups was revealed in respect of paediatric and neurodevelopmental disorders, orthopaedic abnormalities, or respiratory problems during the neonatal period indicates that the risk for developmental complications is not increased in children born after amniocentesis in the second trimester.
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| 13. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Mental retardation in Swedish urban children: some epidemiological considerations.
- 1983
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Ingår i: Applied Research in Mental Retardation. - 0270-3092. ; 4:3, s. 207-218
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Tidskriftsartikel (refereegranskat)abstract
- The total population of children born in 1971 and living in Gothenburg, Sweden, by the end of 1977 was screened in order to estimate prevalence figures for various neurodevelopmental disorders. Ninety-four percent of all children assessed attended public preschools. Questionnaires aimed at detecting perceptual, conceptual, motor, and attentional deficits were completed by preschool teachers for 72% of children in these schools. Samples of children with and without problems on the questionnaire were given neuropsychiatric examinations. National registers were searched to identify mentally retarded children not in public preschools. The total population frequency figure for unequivocal mental retardation was almost 1% with an additional 1% of the total population deemed to be of borderline intelligence.
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| 14. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Minor neurodevelopmental disorders in children born to older mothers.
- 1982
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Ingår i: Developmental Medicine and Child Neurology. - 0012-1622. ; 24:4, s. 437-447
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Tidskriftsartikel (refereegranskat)abstract
- In order to test the hypothesis that rates of motor and perceptual deficits in children tend to increase with maternal age, 65 children aged five and six years born to mothers with a mean age of 39.4 years were compared with 55 age-matched children born to mothers with a mean age of 27.9 years. The hypothesis was supported in that fine-motor problems were five times more common among the children born to older mothers than among those born to younger mothers. Visuo-perceptual dysfunction and attentional deficit signs also were much more common among the children of older mothers. The contribution of various associated factors to these results is discussed.
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| 18. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Perceptual, motor and attentional deficits in seven-year-old children. Neurological screening aspects.
- 1983
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Ingår i: Acta Paediatrica Scandinavica. - 0001-656X. ; 72:1, s. 119-124
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Tidskriftsartikel (refereegranskat)abstract
- In an extensive neuropsychiatric study of seven-year-old children, operational criteria for diagnosing minimal brain dysfunction (MBD) syndrome were used. Detailed behavioural assessment and meticulous neurological examination provided the basis for the MBD diagnosis. The time-consuming specialist examination by the child neurologist was considered too sophisticated for use in everyday clinical practice. Therefore, the results obtained at a short neurodevelopmental screening assessment performed by a child psychiatrist were analysed with the aim of finding a limited set of neurological examination items with high discriminating capacity detecting for MBD syndromes. A set of six such items (diadochokinesis, hopping on one leg, standing on one leg, cutting out a paper circle, associated movements when walking on lateral sides of feet and the labyrinth test of the WISC) produced a minimal rate of misclassified cases. It is argued that this discriminant set may be useful in everyday child psychiatric and pediatric assessment of children who raise suspicion of suffering from MBD.
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| 19. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Perceptual, motor and attentional deficits in six-year-old children. Epidemiological aspects.
- 1982
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Ingår i: Journal of Child Psychology and Psychiatry, and Allied Disciplines. - 0021-9630. ; 23:2, s. 131-144
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Tidskriftsartikel (refereegranskat)abstract
- A total population study of 4797 six-year-old children attending the public preschools in the city of Göteborg (Gothenburg) has been carried out. A questionnaire with 34 questions about MBD-related problems was distributed to all pre-school teachers. Three thousand four hundred and forty-eight questionnaires were completed. Factor analysis of the questionnaire and empirical results from a pilot study provided the basis for selecting for further study children with pre-school signs and symptoms suggestive of MBD. Neurological, psychiatric and psychological assessment of 82 children with, and 59 children without, pre-school symptoms of MBD revealed that in the index groups 41% of the children, and in the control group 3% of the children, had MBD. Extrapolation procedures gave a total population frequency of 1.2% with severe MBD and a further 5.9% with mild-moderate MBD. A very large questionnaire refusal rate (28%) is discussed. The relevance of the calculated frequency figures, especially as regards the mild-moderate MBD category, cannot be properly evaluated until long-term follow-up has been completed.
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| 20. |
- Gillberg, Christopher, 1950, et al.
(författare)
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Perceptual, motor and attentional deficits in six-year-old children. Screening procedure in pre-school.
- 1982
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Ingår i: Acta Paediatrica Scandinavica. - 0001-656X. ; 71:1, s. 121-129
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Tidskriftsartikel (refereegranskat)abstract
- 3 448 six-year-old Swedish children were screened for perceptual, motor and attentional deficits with the help of a questionnaire containing 34 yes-no questions. Epidemiological aspects of single symptoms and of groups of symptoms are presented. Boys displayed many more problems than girls. Children attending day nurseries had more problems than part-time pre-school children, particularly as regards attention and behaviour. 141 of the children- 82 with and 59 without questionnaire symptoms suggestive of so-called MBD-had been examined in an extended neuro-psychiatric study. A discriminant analysis of the questionnaire was performed for these 141 children which demonstrated that a set of 6 questions had a high discriminating capacity detecting for MBD-syndromes.
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| 22. |
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| 23. |
- Gillberg, I Carina, 1949, et al.
(författare)
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Three-year follow-up at age 10 of children with minor neurodevelopmental disorders. II: School achievement problems.
- 1983
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Ingår i: Developmental Medicine and Child Neurology. - 0012-1622. ; 25:5, s. 566-573
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Tidskriftsartikel (refereegranskat)abstract
- Part I of this paper considered the behavioural problems at age 10 of groups of children from a total population study of six-year-old children in Gothenburg and diagnosed according to strict criteria as suffering from minimal brain dysfunction (MBD), motor perception dysfunction (MPD) or attention deficit disorder (ADD), and a comparison group of normal children. Part II considers school achievement problems at age 10 among the same groups of children. 80 per cent of MBD children had obvious problems in school achievement, compared with 16 per cent in the comparison group. The MPD and ADD groups did not differ significantly from the comparison group in this respect. There was a considerable overlap between behaviour problems and school achievement problems, and the results indicate a gloomy prognosis for both types of problem among children with MBD.
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| 24. |
- Niklasson, Lena, 1947, et al.
(författare)
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Attention deficits in children with 22q.11 deletion syndrome.
- 2005
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Ingår i: Developmental Medicine and Child Neurology. - 0012-1622. ; 47:12, s. 803-807
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Tidskriftsartikel (refereegranskat)abstract
- This study examined attention abilities of children with 22q.11 deletion syndrome. Thirty children (14 males, 16 females; age range 7 to 13y) were given comprehensive neuropsychological and neuropsychiatric assessments. Learning disability was found in 13 children. Superiority in verbal over performance IQ was very common. Attention-deficit-hyperactivity disorder (mainly of inattentive subtype) was diagnosed in 13 children. There appeared to be a relation between low IQ and presence of autism spectrum problems. The presence of attention deficits was clearly supported by the scores on the Child Behavior Checklist and the Conners Questionnaire. On the Becker attention tests the reaction times were significantly longer in the two visual and auditory tests, indicating that the ability to sustain attention is critically impaired in this group. A tendency of inferiority on auditory compared with visual tests was noted but there were no specific problems with the focus-execute aspect of attention.
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| 25. |
- Niklasson, Lena, 1947, et al.
(författare)
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Autism, ADHD, mental retardation and behavior problems in 100 individuals with 22q11 deletion syndrome.
- 2009
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Ingår i: Research in Developmental Disabilities. - : Elsevier BV. - 0891-4222. ; 30:4, s. 763-773
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Tidskriftsartikel (refereegranskat)abstract
- This study assessed the prevalence and type of associated neuropsychiatric problems in children and adults with 22q11 deletion syndrome. One-hundred consecutively referred individuals with 22q11 deletion syndrome were given in-depth neuropsychiatric assessments and questionnaires screens. Autism spectrum disorders (ASDs) and/or attention deficit/hyperactivity disorder (ADHD) were diagnosed in 44 cases. ASD was diagnosed in 23 cases of whom only 5 had autistic disorder. ADHD was diagnosed in 30 individuals. In nine of these cases with ASD or ADHD there was a combination of these diagnoses. Mental retardation (MR) with or without ASD/ADHD was diagnosed in 51 individuals. ASD, ADHD, and/or MR were present in 67 cases. Females had higher IQ than males. The results of this study showed that the vast majority of all individuals with 22q11 deletion syndrome have behavior and/or learning problems and more than 40% meet criteria for either ASD, ADHD or both. Neuropsychiatric and neuropsychological evaluations are indicated as parts of the routine clinical assessment of individuals with 22q11 deletion syndrome.
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| 26. |
- Niklasson, Lena, et al.
(författare)
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Chromosome 22q11 deletion syndrome (CATCH 22): neuropsychiatric and neuropsychological aspects.
- 2002
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Ingår i: Developmental Medicine and Child Neurology. - 0012-1622. ; 44:1, s. 44-50
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Tidskriftsartikel (refereegranskat)abstract
- Twenty children and young adults (age range 5 to 33 years, 12 females and eight males) with genetically confirmed 22q11 deletion syndrome (CATCH 22: Cardiac anomaly, Anomalous face, Thymus hypoplasia/aplasia, Cleft palate, and Hypocalcaemia), recruited from a large ongoing study, were given comprehensive assessments with a view to determining the pattern of neuropsychiatric and neuropsychological deficits thought to be part of the syndrome in many cases. IQ ranged between 46 and 100 with a mean score of 70. Half the group had an IQ <70. In 13 individuals, attention-deficit–hyperactivity disorder (ADHD), mainly inattentive or combined type in most cases, and/or autism spectrum problems were diagnosed. Many participants, even among those who had an IQ within the normal range and had neither ADHD nor autistic spectrum problems, showed a characteristic and pronounced behavioural profile with low mental energy, initiation difficulties, deficits in sustained attention, and social interaction (often augmented by limited facial expression and communication and speech problems).
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| 27. |
- Rasmussen, Peder, 1944, et al.
(författare)
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Autistic disorders in Down syndrome: background factors and clinical trials
- 2001
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Ingår i: Developmental Medicine and Child Neurology. ; 43:11, s. 750-754
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Tidskriftsartikel (refereegranskat)abstract
- A study of a clinic-based sample of 25 individuals (12 females, 13 males; age at diagnosis 14.4 years, SD 7.4 years; age range 4 to 33 years) with Down syndrome (DS) and autism spectrum disorders, demonstrates that autism is by no means rare in DS. Results showed that there was a considerable delay in the diagnosis of autism as compared with children with autism who did not have DS. In 11 participants medical factors were identified that were likely to be of importance in contributing to the development of autism, and in four further participants there were factors of possible significance. Such factors include a history of autism or autism-related disorders in first- or second-degree relatives (n=5), infantile spasms (n=5), early hypothyroidism (n=3), evidence of brain injury after complicated heart surgery (n=2), or a combination of these factors. It is important that autism is recognised, identified, and fully assessed in individuals with DS in order for them to receive appropriate education and support.
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| 28. |
- Rasmussen, Peder, 1944, et al.
(författare)
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Natural outcome of ADHD with developmental coordination disorder at age 22 years: a controlled, longitudinal, community-based study.
- 2000
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Ingår i: Journal of the American Academy of Child and Adolescent Psychiatry. - : Elsevier BV. - 0890-8567. ; 39:11, s. 1424-1431
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Tidskriftsartikel (refereegranskat)abstract
- Objective: There is a need for controlled longitudinal studies in the field of attention disorders in the general population. Method: In a community-based follow-up study, 55 of 61 subjects aged 22 years, who had attention-deficit/hyperactivity disorder (ADHD) with and without comorbid developmental coordination disorder (DCD) at initial workup at age 7 years, were compared, on a multitude of outcome variables, with 46 of 51 age-matched subjects without such diagnoses. None of the subjects had received stimulant treatment. Psychiatrists performing the follow-up study were blind to original diagnostic group status. Results: In the ADHD/DCD group 58% had a poor outcome compared with 13% in the comparison group (p 001). Remaining symptoms of ADHD, antisocial personality disorder, alcohol abuse, criminal offending, reading disorders, and low educational level were overrepresented in the ADHD/DCD groups. The combination of ADHD and DCD appeared to carry a particularly gloomy outlook. Conclusions: Childhood ADHD and DCD appears to be a most important predictor of poor psychosocial functioning in early adulthood. It would seem appropriate to screen for such disorders in schools and clinics so that therapies may be started early.
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| 29. |
- Rasmussen, Peder, 1944, et al.
(författare)
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Perceptual, motor and attentional deficits in seven-year-old children: neurological and neurodevelopmental aspects.
- 1983
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Ingår i: Developmental Medicine and Child Neurology. - 0012-1622. ; 25:3, s. 315-333
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Tidskriftsartikel (refereegranskat)abstract
- This study presents the results of neurological assessments of a representative sample of seven-year-old Swedish children with perceptual, motor and attentional deficits and their controls (N = 141). Among those children diagnosed as suffering from minimal brain dysfunction (MBD), the majority showed neurodevelopmental deviations indicative of the "clumsy child syndrome'. However, 20 per cent had slight signs of choreoathetosis, diparesis, hemiparesis or ataxia. Other associated neurodevelopmental deviations are considered. The correlation between neurological findings and background factors is discussed: the MBD group had higher scores for various "organic' background factors than the comparison children, and the children with neurological syndromes had somewhat higher scores than the remaining children with MBD. The difficulties in distinguishing MBD from mental retardation, cerebral palsy and childhood psychoses is clearly illustrated. Long-term follow-up will indicate the prognostic significance of these findings.
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| 30. |
- Rasmussen, Peder, 1944, et al.
(författare)
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Perceptual, motor and attentional deficits in seven-year-old children. Paediatric aspects.
- 1983
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Ingår i: Acta Paediatrica Scandinavica. - 0001-656X. ; 72:1, s. 125-130
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Tidskriftsartikel (refereegranskat)abstract
- 42 children representative of Swedish urban seven-year-olds with a combination of various minor neurodevelopmental deficits in the form of so-called minimal brain dysfunction (MBD) syndromes were compared with 51 children of the same age without such problems as regards general health data from parents' interviews and questionnaires and from paediatric examinations. The findings at the physical examination revealed only few and small differences concerning minor physical anomalies that, in part, is dealt with in a separate report. Children with MBD had experienced simple febrile convulsions significantly more often than controls, and an abnormal EEG was a common finding in these cases. So-called psychosomatic complaints were not overrepresented in the MBD group, but enuresis and encopresis was somewhat more common. The parents' answers to a set of 6 questions (concerned with late speech development, late motor development, gross motor clumsiness, fine motor clumsiness, "shuffling" and difficulties to concentrate) were found to have a high discriminating capacity detecting for MBD syndromes. The possibility of a clinical application of this finding is discussed.
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