| 1. |
- Palm, Kristina, et al.
(författare)
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Digitalisering och arbetsmiljö
- 2020
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Ingår i: Framtidens arbetsmiljö – trender, digitalisering och anställningsformer. - 9789198596151 ; , s. 33-80
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Bokkapitel (refereegranskat)
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| 2. |
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| 3. |
- Rosengren, Calle, et al.
(författare)
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Framtidens kontor
- 2022
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Ingår i: Framtidens arbetsliv: Arbetsvillkor och arbetsmiljö. - Lund : Studentlitteratur. - 9789144153100 - 9144153104 ; , s. 315-338
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Bokkapitel (refereegranskat)
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| 4. |
- Alpenberg, Sara, et al.
(författare)
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Feeling Confident in Using PICC Lines – Patients' Experiences of Living With a PICC Line During Chemotherapy Treatment
- 2015
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Ingår i: Home Health Care Management & Practice. - : SAGE Publications. - 1084-8223 .- 1552-6739. ; 27:3, s. 119-125
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Tidskriftsartikel (refereegranskat)abstract
- Treatments involving chemotherapy require central venous access, such as a Peripherally Inserted Central (PICC) line. The aim of the study was to describe patients’ experiences of living with a PICC line during chemotherapy treatment. The study comprised interviews with 10 patients and was analyzed using manifest qualitative content analysis. The categories The importance of security, The importance of contentedness, and Feeling confident in using the PICC line were identified. To contribute to patient safety and empowerment in health care, nurses must be well trained in PICC line care. Therefore, evidence-based knowledge about central venous access is necessary for patients’ security and contentedness and to improve quality of care and increase patients’ well-being in central venous access care activities in the future. Keywords cancer, chemotherapy, PICC line, qualitative content analysis, sense of coherence (SOC)
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| 5. |
- Andelid, Kristina, 1953, et al.
(författare)
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Myeloperoxidase as a marker of increasing systemic inflammation in smokers without severe airway symptoms
- 2007
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Ingår i: Respiratory medicine. - : Elsevier BV. - 0954-6111. ; 101:5, s. 888-95
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: There is increasing evidence of systemic inflammation in patients with chronic obstructive pulmonary disease (COPD), but there is very little information on the development of systemic inflammation in smokers without severe airway symptoms. In this longitudinal study, we examined whether smokers with mild or no airway symptoms develop signs of systemic inflammation by assessing inflammatory markers in blood over a 6-year period. METHODS: Forty smokers and 28 male never-smokers were investigated in 1995 (year 0) and 6 years later (year 6). At year 6, 11 smokers had stopped smoking (quitters); these subjects were analysed as a separate group. At year 0 and 6, we measured serum levels of myeloperoxidase (MPO), lysozyme and human neutrophil lipocalin (HNL), regarded as markers of activity in neutrophils plus monocyte-lineage cells, monocyte-lineage cells only and neutrophils only. RESULTS: All systemic markers of inflammation (MPO, HNL and lysozyme) were significantly higher in smokers than in never smokers at year 6. For MPO alone, smokers only displayed a unique pattern compared with the other groups; the concentration of MPO in blood increased among smokers during the 6-year period, and this increase was statistically significant compared with that observed in never-smokers. Even though quitters did not display any clear change in MPO, we observed a statistically significant negative correlation between the change in blood MPO and the duration of smoking cessation in this group. For HNL and lysozyme, the changes over time were similar in smokers and never-smokers, with no statistically significant difference compared with quitters. CONCLUSION: This study provides evidence that male smokers without severe airway symptoms develop an increasing systemic inflammation during a 6-year period. The study forwards both direct and indirect evidence that MPO may be an early marker of this systemic inflammation. However, our study also forwards indirect evidence that ongoing tobacco smoking may "drive" the level of systemic HNL and lysozyme. The origin of the increased MPO and its value as an easily measured predictor for future COPD deserves to be further evaluated.
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| 6. |
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| 7. |
- Andersson, Erika, et al.
(författare)
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To Be Involved – a Qualitative Study of Nurses' with Limited Experiences of Caring for Dying Patients
- 2016
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Ingår i: Nurse Education Today. - : Elsevier BV. - 0260-6917 .- 1532-2793. ; 38, s. 144-149
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Tidskriftsartikel (refereegranskat)abstract
- Objective The aim of this study was to describe nurses' experiences (> two years) of caring for dying patients in surgical wards. Background Palliative care is included in education for nurses. However, the training content varies, and nurse educators need to be committed to the curriculum regarding end-of-life situations. A lack of preparation among newly graduated nurses regarding dying and death could lead to anxiety, stress and burnout. Therefore, it is important to improve knowledge regarding end-of-life situations. Setting, Participants and Method A qualitative descriptive study was carried out in two surgical wards in the southern part of Sweden. The study comprised six interviews with registered nurses and was analysed using manifest qualitative content analysis, a qualitative method that involves an inductive approach, to increase our understanding of nurses' perspectives and thoughts regarding dying patients. Results The results formed one category (caring—to be involved) and three subcategories (being supportive, being frustrated and being sensitive in the caring processes). Nurses were personally affected and felt unprepared to face dying patients due to a lack of knowledge about the field of palliative care. Their experiences could be described as processes of transition from theory to practice by trial and error. Conclusion Supervision is a valuable tool for bridging the gap between theory and practice in nursing during the transition from novice to expert. Improved knowledge about palliative care during nursing education and committed nursing leadership at the ward level facilitate preparation for end-of-life situations.
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| 8. |
- Andersson, Julia, et al.
(författare)
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Documentation of pressure ulcers in medical records at an internal medicine ward in university hospital in western Sweden
- 2023
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Ingår i: Nursing Open. - : Wiley. - 2054-1058. ; 10:3, s. 1794-1803
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: Pressure ulcers cause suffering, prolong care periods, and increase mortality. The aim was to describe and analyze the documentation of pressure ulcers and focused on the medical records from an internal medicine ward in a university hospital in western Sweden. Methods: A quantitative, retrospective review of medical records was conducted for all care events (n = 1,458) with descriptive statistics. Results: Documentation of the pressure ulcers in care plans was 2.1% (n = 31) compared to 6.7% (n = 46) within final notes written by registered nurses (RN), a lower result compared to PPM (n = 3/14, 21.4%). Risk assessments were carried out in 68 (4.7%) care events, and 31 care plans included pressure ulcers. Moreover, 198 cases of tissue damage were documented, 43 (21.7%) defined as pressure ulcers, the other 147 (74.2%) lacked definition. Conclusions: Differences (2.1%-21.4%) highlight improvements; knowledge and communication of pressure ulcers ensure reliable documentation in medical records.
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| 9. |
- Antoni, Gunnar, et al.
(författare)
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In Vivo Visualization of Amyloid Deposits in the Heart with C-11-PIB and PET
- 2013
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Ingår i: Journal of Nuclear Medicine. - : Society of Nuclear Medicine. - 0161-5505 .- 1535-5667 .- 2159-662X. ; 54:2, s. 213-220
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Tidskriftsartikel (refereegranskat)abstract
- Cardiac amyloidosis is a differential diagnosis in heart failure and is associated with high mortality. There is currently no noninvasive imaging test available for specific diagnosis. N-[methyl-C-11]2-(4'-methylamino-phenyl)-6-hydroxybenzothiazole (C-11-PIB) PET is used in the evaluation of brain amyloidosis. We evaluated the potential use of C-11-PIB PET in systemic amyloidosis affecting the heart. Methods: Patients (n = 10) diagnosed with systemic amyloidosis-including heart involvement of either monoclonal immunoglobulin light-chain (AL) or transthyretin (ATTR) type- and healthy volunteers (n = 5) were investigated with PET/CT using C-11-PIB to study cardiac amyloid deposits and with C-11-acetate to measure myocardial blood flow to study the impact of global and regional perfusion on PIB retention. Results: Myocardial C-11-PIB uptake was visually evident in all patients 15-25 min after injection and was not seen in any volunteer. A significant difference in C-11-PIB retention in the heart between patients and healthy controls was found. The data indicate that myocardial amyloid deposits in patients diagnosed with systemic amyloidosis could be visualized with C-11-PIB. No correlation between C-11-PIB retention index and myocardial blood flow as measured with C-11-acetate was found on the global level, whereas a positive correlation on the segmental level was seen in a single patient. Conclusion: C-11-PIB and PET could be a method to study systemic amyloidosis of type AL and ATTR affecting the heart and should be investigated further both as a diagnostic tool and as a noninvasive method for treatment follow-up.
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| 10. |
- Antonsson, Helen, et al.
(författare)
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First-line managers’ experiences of alternative modes of funding in elderly care in Sweden
- 2012
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Ingår i: Journal of Nursing Management. - : Hindawi Limited. - 0966-0429 .- 1365-2834. ; 20:6, s. 737-747
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Tidskriftsartikel (refereegranskat)abstract
- Aim: The aim of this study was to describe first-line managers’ experiences of alternative modes of funding elderly care in two communities in western Sweden. Background: A growing elderly population demands alternative modes of funding elderly care for better outcomes for patients and better efficiency as it is publicly funded through taxation. Methods: The study comprised a total of eight semi-structured interviews with first-line managers working within elderly care. The interviews were analysed using manifest qualitative content analysis. Respect for the individuals was a main concern in the study. Results: One category, quality improvement, and four subcategories freedom of choice, organisational structure, quality awareness and market forces effects were identified to describe first-line managers’ experiences of the operation of elderly care. Conclusions: Quality improvement was an important factor to deal with when elderly care was operated in different organisational perspectives, either private or public. The first-line manager is a key person for developing a learning organisation that encourages both staff, clients and their relatives to improve the organisation. Moreover, person-centred care strengthens the client’s role in the organisation, which is in line with the government’s goal for the quality improvement of elderly care. However, further research is needed on how quality improvement could be developed when different caregivers operate in the same market in order to improve care from the elderly perspective.Implications for nursing management: This study highlights alternative modes of funding elderly care. The economical perspectives should not dominate without taking care of quality improvement when the operation of elderly care is planned and implemented. Strategies such as a learning organisational structure built on person-centred care could create quality improvement in elderly care.
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| 11. |
- Bergman, Ann, et al.
(författare)
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Digitala strategier för att hantera relationen mellan arbete och övrigt liv
- 2020
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Ingår i: Att arbeta för lika villkor: Ett genus- och maktperspektiv på arbete och organisation. - 9789144135045
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Bokkapitel (refereegranskat)abstract
- Det här kapitlet fokuserar på relationen mellan arbetsliv och övrigt liv och ett antal digitala strategier som används för att hantera denna. Tidigare forskning har visat att kvinnor i jämförelse med män möter en större utmaning i hanterandet av denna gränsdragning, givet att kvinnor, traditionellt sett, har haft ansvaret för barn samt utfört mer av det obetalda arbetet i hemmet (Hochschild & Machung 2012). Kapitlet belyser denna gränsdragningsproblematik med ett specifikt fokus på hur den tar sig uttryck i samband med användandet av informations- och kommunikationsteknologi (IKT). De digitala gränshanteringsstrategierna kan förstås utifrån ett aktörsorienterat synssätt med fokus på individen, dennas intentioner och personliga preferenser. De kan även förstås utifrån ett strukturellt synsätt med fokus på strukturella villkor inom arbetsliv och privatliv. Kapitlet belyser hur aktör och struktur samverkar genom att presentera resultat från en kvalitativ studie av anställda inom industrin.
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| 12. |
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| 13. |
- Bergman, Ann, et al.
(författare)
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Mixing work and private activities in the digital working life. A diary study.
- 2017
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Konferensbidrag (refereegranskat)abstract
- Laptops and smartphones are now challenging the traditional boarders of work and have contributed to new ways of combining work and other parts of life. Both time and room dimensions have been resolved or taken new forms through the new information and communication technology. Questions like when and where you are supposed to, or can or want to work are likewise important to companies and employees. Issues around the relationship between working life and family life have in addition to this become more important when the traditional roles between men and women are changing. When work is being done on the cost of engagement in the private sphere it often leads to stress and role conflicts, so-called spillover. Spillover is a risk factor for health and well-being, but there are still knowledge gaps on how this risk can be managed by organizations as well as individuals. This conference paper is based on an ongoing research project with the overall aim of developing guidelines for how organisations may work to promote a sustainable working life. There is a special focus on how women and men in different periods of life can be offered good prerequisites in combining work and private life. In close collaboration with two global companies in Sweden we are doing an explorative diary and interview study with employees, the employees’ families and managers and human resource on how they manage the challenges of the digital working life. Specific research questions:1)What strategies do employees use to handle the demands on and possibilities that the digital technology creates for being available to work and family?2)How do the employee, its partner and children experience the effects of digital technology on family life?3)How do managers and human resources handle the digital technology in relation to a sustainable working environment?In this conference paper we are presenting preliminary results from the diary study that will be carried out by about 40 – 50 employees. These employees have been chosen because they have the possibility to locate part of their work outside the workplace and outside normal office hours. The respondents should during seven days in a manual diary log how they 1) during normal office hours are doing private related activities (such as talking to the phone with the partner or child, or booking a doctor’s appointment) and 2) outside normal office hours perform work tasks (such as reading and answering emails on the phone or preparing meetings in the computer). The diary entails what kind of task has been performed, with what technology, how long it did take, when and where it was performed, who else were in the room and with what feeling it was made. The diary is divided into seven time slots during a day, and the respondent should also summarize each time slot with words like stressful, relaxed, and chaos. Finally the respondents should describe if the time slot is “normal” or not, and if not how it differed from the “normal”. The diary data material will be analyzed from dimensions of sex, period in life and the experiences of the work-life relation, but also the working conditions and well-being.The overall results of the study should contribute to improving the systematic work on work environment that also include the work conditions that managers normally don’t see and have control over. That is when work is done outside the four walls of the office and the normal office hours. This is up-to-date crucial in Sweden since the Swedish work environment authority has new regulations on organizational and social work environment (AFS 2015:4) that also includes workloads and working hours.
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| 14. |
- Bergman, Ingrid-Maria, et al.
(författare)
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Extensive polymorphism in the porcine Toll-like receptor 10 gene
- 2012
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Ingår i: International Journal of Immunogenetics. - 1744-3121 .- 1744-313X. ; 39:1, s. 68-76
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Tidskriftsartikel (refereegranskat)abstract
- The great importance of the Toll-like receptors (TLRs) in innate immunity is well established, but one family member – TLR10 – remains elusive. TLR10 is expressed in various tissues in several species, but its ligand is not known and its function is still poorly understood. The open reading frame of TLR10 was sequenced in 15 wild boars, representing three populations, and in 15 unrelated domestic pigs of Hampshire, Landrace and Large White origin. Amino acid positions corresponding to detected nonsynonymous single nucleotide polymorphisms (SNPs) were analysed in the crystal structures determined for the human TLR1–TLR2–lipopeptide complex and the human TLR10 Toll/Interleukin 1 receptor (TIR) dimer. SNP occurrence in wild boars and domestic pigs was compared, and haplotypes for the TLR10 gene and the TLR6-1-10 gene cluster were reconstructed. Despite the limited number of animals sequenced in the present study (N = 30), a larger number of SNPs were found in TLR10 than recently reported for TLR1, TLR6 and TLR2. Thirty-three SNPs were detected, of which 20 were nonsynonymous. The relative frequency of nonsynonymous (dN) and synonymous (dS) SNPs between wild boars and domestic pigs was higher in TLR10 than recently reported for TLR1, TLR6 and TLR2. However, the polymorphism reported in the present study seems to leave the function of the TLR10 molecule unaffected. Furthermore, no nonsynonymous SNPs were detected in the part of the gene corresponding to the hinge region of the receptor, probably reflecting rigorously acting functional constraint. The total number of SNPs and the number of nonsynonymous SNPs were significantly lower (P < 0.05) in the wild boars than in the domestic pigs, and fewer TLR10 haplotypes were present in the wild boars. The majority of the TLR6-1-10 haplotypes were specific for either wild boars or domestic pigs, probably reflecting differences in microbial environment and population history.
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| 15. |
- Bernhed, Johanna, et al.
(författare)
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Dare to Care: A Qualitative Content Analysis Regarding Nursing Students' View on HIV in Vietnam
- 2018
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Ingår i: Home Health Care Management and Practice. - : SAGE Publications. - 1084-8223 .- 1552-6739. ; 30:4, s. 187-194
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Tidskriftsartikel (refereegranskat)abstract
- In Vietnam, HIV-positive population, as well as the stigmatization of this disease, is increasing, which affects patients and staff, thus requiring improvement. Nurses have a central role in adopting UNAIDS 90-90-90 vision regarding knowledge and treatment without risk. The aim of this study is to describe nursing students' experiences with HIV in Hanoi, Vietnam. Interviews with seven nursing students were performed. Data were analyzed using content analysis. The results formed one category, dare to care, and three subcategories: being careful, managing fear, and creating trust. This study highlighted the importance of awareness of values (visualize stigmatization) to develop guidelines (built on evidence-based knowledge) to transform knowledge (theoretical, practical) through nursing skills that are performed to manage fear and create trustful care for HIV-positive patients.
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| 16. |
- Brijs, J., et al.
(författare)
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Prospects and pitfalls of using heart rate bio-loggers to assess the welfare of rainbow trout (Oncorhynchus mykiss) in aquaculture
- 2019
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Ingår i: Aquaculture. - : Elsevier BV. - 0044-8486 .- 1873-5622. ; 509, s. 188-197
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Tidskriftsartikel (refereegranskat)abstract
- - Investigating real-time stress responses during common aquaculture practices is necessary for improving the welfare of farmed fish. Recently, Star-Oddi DST milli-HRT bio-loggers capable of measuring heart rate (as an indicator for stress) in freely swimming fish have proved to be useful in this regard. However, despite the growing popularity of these devices, they have not yet been stringently evaluated and validated for use in fish. The present study is the first to do so by simultaneously recording heart rate of a commercially important salmonid species (rainbow trout, Oncorhynchus mykiss) using the abovementioned bio-loggers, as well as an established non-invasive wireless heart rate recording technique that has been demonstrated to provide more accurate recordings than those collected using traditional methods requiring a physical connection to recording equipment. The measurement error of the bio-loggers was <1 beat min −1 irrespective of the sampling period when only using measurements graded with the highest quality index (QI 0 ) and it is advised that only QI 0 measurements be used as inclusion of poorer quality measurements (QI 1–3 ) markedly reduce measurement accuracy. Furthermore, sufficiently long recovery periods should be employed prior to collecting data with these devices in salmonids, as anaesthesia and surgical implantation of bio-loggers resulted in transiently elevated resting heart rates for >72 h. Following the successful validation of these bio-loggers, the effects of common aquaculture practices such as netting, grouping and enforced activity on the cardiac performance of freely swimming rainbow trout were investigated. Prior to the subsequent exposure to the abovementioned stressors, mean heart rates of trout were ~42 beats min −1 . Following netting, trout increased heart rates by 57%, which recovered within 3 h. Grouping subsequently induced a more pronounced and prolonged stress response, as heart rates initially increased by 86% and then remained elevated throughout the 8 h recovery period. Consequently, trout were only able to further increase heart rates by 7% following enforced activity. This diminished cardiac response demonstrates a situation where the cumulative allostatic load induced by prior stressors is approaching a level where the animal struggles to perform normal physiological processes in the face of further challenges. These findings are important for the aquaculture industry as exposure to multiple stressors without sufficient recovery times has the potential to result in the collapse of cardiac scope, which combined with unfavourable environmental conditions could lead to increased mortality. © 2019 Elsevier B.V.
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| 17. |
- Byberg, Linda, et al.
(författare)
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Nurses’ experiences of caring for patients with tuberculosis – An interview study in Indonesia
- 2019
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Ingår i: International Archives of Nursing and Health Care. ; 5:4
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Tidskriftsartikel (refereegranskat)abstract
- Abstract Background: Tuberculosis, TB is an infectious disease affecting millions of people each year and Indonesia have the second highest prevalence in the world. The cure of TB is already existing but hence to factors such as long treatment with severe side-effects results in low compli- ance. The aim of the study was to describe nurse’s con- ceptions of caring for patients suffering from tuberculosis in Yogyakarta, Indonesia. Method: Individual interviews were conducted with ten nurses at different hospitals and primary health centers. The material was analysed with a phenomenographic ap- proach. Findings: Three categories were described; “The concep- tions of tuberculosis as a contagious disease”, “The con- ceptions of the nurse’s role” and “The conceptions of the patient’s situation”. Results showed that precautions and protection of transmission was the most prominent concep- tion related to tuberculosis-care. Another point of view was nurse’s role as an educator to improve patient’s knowledge regarding precautions and treatment plan. Conclusion: To perform nursing, precautions and protec- tion is significant even though medication for TB is free of charge. However, other economic factors remain as well as manage the complexity of TB for example multidrug-resis- tance (MDR), calls for further research.
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| 18. |
- Bäcklander, Gisela, et al.
(författare)
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Distansarbete före, under och efter pandemin
- 2023
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Ingår i: Ett hälsofrämjande arbetsliv? : Utmaningar och möjligheter - Utmaningar och möjligheter. - 9789144158525 ; , s. 123-150
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Bokkapitel (refereegranskat)
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| 19. |
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| 20. |
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| 21. |
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| 22. |
- Cadier, Filip, et al.
(författare)
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Nursing students' experiences with type 2 diabetes in Jordan: a qualitative content analysis
- 2017
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Ingår i: Home Health Care Management & Practice. - : SAGE Publications. - 1084-8223 .- 1552-6739. ; 29:2, s. 103-110
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Tidskriftsartikel (refereegranskat)abstract
- Prevalence of type 2 diabetes has increased worldwide due to lifestyle factors, such as obesity and inactivity and nurses have an essential role in supporting healthy life situations. The aim was to describe nursing students' experiences with type 2 diabetes in Jordan regard to prevention and nursing care. Interviews with eight nursing students were performed. Data were analyzed using content analysis. One category and two subcategories were generated: managing challenges in daily life to prevent type 2 diabetes and promote patient safety, managing risk factors, and dealing with difficulties. Empowerment and person-centered care are tools to increase patients’ self-care to motivate them to live a healthy lifestyle within the whole family to prevent and decrease illness.
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| 23. |
- Carney Almroth, Bethanie, 1974, et al.
(författare)
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Warmer water temperature results in oxidative damage in an Antarctic fish, the bald notothen
- 2015
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Ingår i: Journal of Experimental Marine Biology and Ecology. - : Elsevier BV. - 0022-0981 .- 1879-1697. ; 468, s. 130-137
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Tidskriftsartikel (refereegranskat)abstract
- Global climate change is predicted to result in increases in water temperature in the polar regions, but the full consequences of this for marine fish species are not understood, especially with regard to cellular mechanisms underlying oxidative stress. Warmer temperatures could potentially result in increased oxidative stress, and it is not known whether stenothermal fish can cope with this on a cellular and physiological level. In order to address this, we exposed bald notothen (Pagothenta borchgrevinki), a fish species endemic to Antarctica, to an increase in temperature from -1.6 degrees C to 4 degrees C and measured the effects on oxidative stress including antioxidant defenses, oxidative damage in proteins and lipids, and transcriptional regulation of involved genes. We show that the fish responds to an acute (12 h) temperature increase with increased antioxidant defenses. However, these antioxidant defenses were similar to basal levels following long-term (3 weeks) exposure to the higher temperature and moreover, these individuals also had higher levels of oxidative damage. These results indicate that this species has the ability to alter levels of endogenous antioxidants, but that this response is transient and insufficient to protect against oxidative damage. These effects may have serious consequences for these fish in a warmer future since long-term consequences of this accumulation of damaged lipids and proteins are associated with aging and known to include decreased cellular function, disease and eventually cell death. (C) 2015 Elsevier B.V. All rights reserved.
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| 24. |
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| 25. |
- Démeh, Waddah, et al.
(författare)
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The Visualization of Clinical Leadership in the Content of Nursing Education – a Qualitative Study of Nursing Students’ Experiences.
- 2015
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Ingår i: Nurse Education Today. - : Elsevier BV. - 0260-6917 .- 1532-2793. ; 35:7, s. 888-893
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Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this study was to describe nursing students’ experiences of clinical leadership during their last year of education. Background: Work as a nurse is complex with several demands from stakeholders who are colleagues, managers, patients and relatives. Therefore, it is important to provide students with tools for a forthcoming professional life as a nurse. Setting, Participants and Method: A qualitative descriptive study was carried out in Jordan. Narratives (n=20) written by nursing students in their last year before graduation as a registered nurse were collected. The data were analysed by a manifest content analysis. Results: The results formed one category:(Clinical leadership – safety in being a nurse), and three subcategories (eye-opener, a role model and bridging the gap) described the students’ clinical leadership experiences due to the preparation process for being a nurse. Clinical leadership applies theory to practice by using a holistic view in nursing. Conclusion: Clinical leadership is a valuable tool for bridging the gap between theory and practice in nursing education. Skills within nursing management clarify and simplify nursing activities, which facilitates the transition from student to nurse. Focus on learning needs in nursing management is needed for stakeholders within education and health care organisations to facilitate graduation of well skilled nurses.
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| 26. |
- Dotevall, Camilla, et al.
(författare)
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Nursing students' experiences with refugees with mental health problems in Jordan: a qualitative content analysis
- 2018
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Ingår i: Nurse Education Today. - : Elsevier BV. - 0260-6917 .- 1532-2793. ; 61, s. 155-161
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: The aim of this study was to describe Jordanian nursing students' experiences with caring for refugees with mental health problems. Background: A well-educated staff is necessary to provide a high quality of care to refugees with mental health problems caused by traumatic experiences. Therefore, health professionals play an important role in creating an environment that promotes human rights regardless of ethnic origin. Settings, Participants, Methods: In this study, eight interviews were conducted, and the results were analysed by content analysis, a qualitative method that uses an inductive approach, to increase our understanding of nursing students’ perspectives and thoughts regarding caring for refugees with mental health problems. Results: The results formed one category (being challenged by refugees’ mental health issues) and three subcategories (managing refugees’ mental health needs, being affected by refugees’ mental health, and improving mental healthcare for refugees). Conclusion: Language problems can be managed by using interpreters to decrease cultural clashes to facilitate equal healthcare. In addition, well-educated (theoretical knowledge) and trained (practical knowledge) nursing students have the potential to fulfil refugees’ care needs regardless of ethnicity or background by using nursing interventions built on communication skills.
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| 27. |
- Dunder, Kristina, 1961-
(författare)
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Clinical Manifestations of Coronary Heart Disease and the Metabolic Syndrome : A Population-based Study in Middle-aged Men in Uppsala
- 2004
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- During the past decades the knowledge concerning risk factors and pathophysiology of coronary heart disease (CHD) has substantially increased. However, despite identification of important risk factors CHD remains the leading cause of death in the western world.The metabolic syndrome is a cluster of metabolic disorders such as hypertension, hypertriglyceridemia, low HDL-cholesterol, and glucose intolerance associated with an increased risk of cardiovascular morbidity and mortality.The studies in this thesis are epidemiological in their character, and examine the relationships between different aspects of CHD and the metabolic syndrome in a population-based study of middle-aged men (ULSAM).The findings indicated that serum lipids were important risk factors for the development of both angina pectoris demanding revascularisation and acute myocardial infarction (MI). Proinsulin and blood pressure were independent predictors of MI only, suggesting these factors to be involved in thrombosis and plaque rupture. It was also found that antihypertensive treatment with beta-blockers and thiazide diuretics resulted in increased fasting blood glucose concentrations in subjects with an insulin resistant state with elevated proinsulin concentrations. Both proinsulin concentrations and increase in fasting blood glucose were associated with increased risk of developing future MI. The finding of a new Q/QS-pattern on the resting ECG, regardless of history of MI, was associated with impaired insulin secretion and was an independent predictor of total and cardiovascular mortality. A risk prediction score for MI including proinsulin and the ratio between apolipoprotein B and apolipoprotein A1 was developed in middle-aged men. This score was predictive for future fatal and nonfatal MI, and proved to be at least as good as the Framingham and the PROCAM scores, being based on traditional risk factors.In summary these studies provide further knowledge about the associations between CHD and the metabolic syndrome and the possible importance of new markers of cardiovascular risk such as proinsulin and the apolipoproteins.
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| 28. |
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| 29. |
- Engberg, Anna, 1982-, et al.
(författare)
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BLOOD PROTEIN-POLYMER ADSORPTION FINGERPRINTING:IMPLICATIONS FOR UNDERSTANDING HEMOCOMPATIBILITYAND FOR BIOMATERIAL DESIGN
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Within seconds after an artificial material has been implanted into the blood thesurface will be covered by adsorbed plasma proteins. The composition of theprotein layer is determined by the physical-chemical properties of the surface. Asthe layer itself will become the new interface between the material and blood, itis of major importance for the hemocompatibility. In this project we have studiedthe adsorption of proteins to a model material (polystyrene, PS) with the peptidemass fingerprint technique (PMF) analyzed on a Matrix Assisted LaserDesorption/Ionization Time-of-Flight (MALDI-TOF). To further be able to studythe adsorption of plasma proteins to polymer surfaces, we have synthesized 33new polymer compositions with variable surface properties. Six of thosepolymers were selected and their protein binding ability was determined as wellas quantification of adsorption of 20 plasma proteins to the surface of thepolymers. Our results showed that fourteen high abundant plasma proteins werepositively identified on the PS-surface by MALDI-TOF. Further, the resultsshowed that the synthesized polymers had very distinctive adsorption patterns,with enrichment of different proteins after incubation in plasma and serum. Oneof the polymers was shown to adsorb large amounts of the complementactivating recognition protein C1q, which makes this polymer to a potentialactivating surface. Two of the polymers showed a clear enrichment of thecomplement regulating protein vitronectin as well as two apolipoproteins (AI andAIV) to the surface of the polymers, while some of the polymers bound proteinsapproximately in correlation to the concentration found in plasma.
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| 30. |
- Engberg, Anna E., et al.
(författare)
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Blood protein-polymer adsorption : Implications for understanding complement-mediated hemoincompatibility
- 2011
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Ingår i: Journal of Biomedical Materials Research - Part A. - : Wiley. - 1549-3296. ; 97A:1, s. 74-84
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to create polymeric materials with known properties to study the preconditions for complement activation. Initially, 22 polymers were screened for complement activating capacity. Based on these results, six polymers (P1-P6) were characterized regarding physico-chemical parameters, for example, composition, surface area, pore size, and protein adsorption from human EDTA-plasma. P2, P4, and reference particles of polystyrene and polyvinyl chloride, were hydrophobic, bound low levels of protein and were poor complement activators. Their accessible surface was limited to protein adsorption in that they had pore diameters smaller than most plasma proteins. P1 and P3 were negatively charged and adsorbed IgG and C1q. A 10-fold difference in complement activation was attributed to the fact that P3 but not P1 bound high amounts of C1-inhibitor. The hydrophobic P5 and P6 were low complement activators. They selectively bound apolipoproteins AI and AIV (and vitronectin), which probably limited the binding of complement activators to the surface. We demonstrate the usefulness of the modus operandi to use a high-throughput procedure to synthesize a great number of novel substances, assay their physico-chemical properties with the aim to study the relationship between the initial protein coat on a surface and subsequent biological events. Data obtained from the six polymers characterized here, suggest that a complement-resistant surface should be hydrophobic, uncharged, and have a small available surface, accomplished by nanostructured topography. Additional attenuation of complement can be achieved by selective enrichment of inert proteins and inhibitors.
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| 31. |
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| 32. |
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| 33. |
- Engberg, Anna E., 1982-, et al.
(författare)
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EVALUATION OF THE HEMOCOMPATIBILITY OF NOVEL POLYMERIC MATERIALS
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Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- When a biomaterial surface comes in contact with blood an immediate adsorption of plasma proteins to the surface will occur, and the cascade systems in the blood, such as the complement, coagulation and contact system, will be activated to various degrees. The intensity of this reaction will determine the hemocompatibility of the materials. Here we present an evaluation of the link between the composition, the physico-chemical properties and the protein adsorption properties of six newly synthesized polymers (P1-P6) and the hemocompatibility.The hemocompatibility of the polymeric surfaces was evaluated in human blood plasma and whole blood. Commercially available polyvinylchloride (PVC) was used as reference material. The hemocompatibility of the polymeric surfaces was evaluated with regard to complement activation (C3a and sC5-9 generation) and coagulation activation (platelet loss and TAT-formation) and cytokine productions (27 analytes in multiplex assay) after contact with whole blood. Contact activation was quantified by analyses of FXIIa-C1INH, FXIa-C1INH, and kallikrein-C1INH complexes.Polymers P2 (p<0.05 for C3a), P3, P5 and P6 showed less complement activation, and polymers P1 and P4 (p<0.05 for platelet loss), as well as P5 and P6 showed less coagulation activation compared with reference PVC. Polymers P1-P3 induced activation of the contact system, P3 being the most potent. Secretion of 17 cytokines including chemokines and growth factors were differentially influenced by the polymers, P1 and P3 being significantly (p<0.05) more compatible for five of the analytes.Collectively these data demonstrate that the composition of the polymers clearly leads to different biological properties as a consequence of distinctive physico-chemical properties and protein adsorption patterns.1
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| 34. |
- Engberg, Anna E., et al.
(författare)
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Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma
- 2015
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Ingår i: Biomaterials. - : Elsevier BV. - 0142-9612 .- 1878-5905. ; 36, s. 55-65
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Tidskriftsartikel (refereegranskat)abstract
- Inappropriate complement activation is often responsible for incompatibility reactions that occur when biomaterials are used. Complement activation is therefore a criterion included in legislation regarding biomaterials testing. However, no consensus is yet available regarding appropriate complement-activation-related test parameters. We examined protein adsorption in plasma and complement activation/cytokine release in whole blood incubated with well-characterized polymers. Strong correlations were found between the ratio of C4 to its inhibitor C4BP and generation of 10 (mainly pro-inflammatory) cytokines, including IL-17, IFN-gamma, and IL-6. The levels of complement activation products correlated weakly (C3a) or not at all (C5a, sC5b-9), confirming their poor predictive values. We have demonstrated a direct correlation between downstream biological effects and the proteins initially adhering to an artificial surface after contact with blood. Consequently, we propose the C4/C4BP ratio as a robust, predictor of biocompatibility with superior specificity and sensitivity over the current gold standard. (C) 2014 Elsevier Ltd. All rights reserved.
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| 35. |
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| 36. |
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| 37. |
- Eriksson, Elin, et al.
(författare)
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Working Through Others - A Qualitative Content Analysis of Nursing Students' Experience with Malnutrition at One Hospital in Vietnam
- 2019
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Ingår i: International Archives of Nursing and Health Care. - : ClinMed International Library. - 2469-5823. ; 5:4
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Tidskriftsartikel (refereegranskat)abstract
- Abstract Background Malnutrition causes problems in Vietnam, including illnesses with physiological and psychological complications. The aim of this study was to describe nursing students' experiences with malnutrition at one hospital in Vietnam. Methods Interviews of eight nursing students were performed, and the results were analysed by qualitative content analysis. Findings The results are presented in one category (working through others) and three subcategories (awareness of malnutrition, developing family-centered care and developing health promotion). Conclusion This study highlights the use of guidelines in collaboration (between staff and patients' relatives) to facilitate early identification and/or prevent malnutrition by improving self-care, as supported through nursing activities using family-centred care as well as teamwork.
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| 38. |
- Evertsson, Paula, et al.
(författare)
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Political experiences of changing the focus in elderly care in one municipality
- 2015
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Ingår i: Journal of Nursing Management. - : Hindawi Limited. - 0966-0429. ; 23:8, s. 994-1002
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Tidskriftsartikel (refereegranskat)abstract
- Aim To describe local politicians’ experiences of an ongoing planning process for elderly care for the future in a medium-sized municipality in western Sweden. Background Elderly care is facing challenges because of an ageing population. Method The study comprised a total of eight semi-structured interviews with politicians. The interviews were analysed using manifest qualitative content analysis. Results One category (political consensus) and three subcategories (involvement generates security, trust in change management and confidence to create visions) were identified. Conclusions Political consensus across elderly care organisations could establish a sense of security for old people, their relatives and the staff in particular. Continuous information and support from different managerial levels is one way of implementing changes within large organisations. However, further research is needed to describe how to develop future elderly care. Implications for nursing management An ageing population requires cooperation across provider boundaries to further develop high-quality elderly care services. Nursing leadership during a change process is crucial to implement political decisions in care organisations. Furthermore, active marketing of the health care profession for elderly care is needed as well as new knowledge regarding old people. Keywords: consensus, cooperation, elderly care, leadership skills, nursing, politicians’ experiences
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| 39. |
- Fadista, Joao, et al.
(författare)
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Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
- 2014
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Ingår i: Proceedings of the National Academy of Sciences. - : Proceedings of the National Academy of Sciences. - 1091-6490 .- 0027-8424. ; 111:38, s. 13924-13929
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Tidskriftsartikel (refereegranskat)abstract
- Genetic variation can modulate gene expression, and thereby phenotypic variation and susceptibility to complex diseases such as type 2 diabetes (T2D). Here we harnessed the potential of DNA and RNA sequencing in human pancreatic islets from 89 deceased donors to identify genes of potential importance in the pathogenesis of T2D. We present a catalog of genetic variants regulating gene expression (eQTL) and exon use (sQTL), including many long noncoding RNAs, which are enriched in known T2D-associated loci. Of 35 eQTL genes, whose expression differed between normoglycemic and hyperglycemic individuals, siRNA of tetraspanin 33 (TSPAN33), 5'-nucleotidase, ecto (NT5E), transmembrane emp24 protein transport domain containing 6 (TMED6), and p21 protein activated kinase 7 (PAK7) in INS1 cells resulted in reduced glucose-stimulated insulin secretion. In addition, we provide a genome-wide catalog of allelic expression imbalance, which is also enriched in known T2D-associated loci. Notably, allelic imbalance in paternally expressed gene 3 (PEG3) was associated with its promoter methylation and T2D status. Finally, RNA editing events were less common in islets than previously suggested in other tissues. Taken together, this study provides new insights into the complexity of gene regulation in human pancreatic islets and better understanding of how genetic variation can influence glucose metabolism.
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| 40. |
- Fedorowski, Artur, et al.
(författare)
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Familial Associations of Complete Atrioventricular Block : A National Family Study in Sweden
- 2023
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Ingår i: Circulation. Genomic and precision medicine. - 2574-8300. ; 16:2
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Complete atrioventricular block (CAVB) is a major reason for implantation of permanent pacemakers, but knowledge of CAVB inheritance is sparse. This nationwide study aimed to determine the occurrence of CAVB in first-, second-, and third-degree relatives (full siblings, half-siblings, and cousins).METHODS: The Swedish multigeneration register was linked to the Swedish nationwide patient register for the period 1997 to 2012. All Swedish full sibling, half-sibling, and cousin pairs born to Swedish parents between 1932 and 2012 were included. Competing risks and time-to-event, subdistributional hazard ratios (SHRs) according to Fine and Gray and hazard ratios using Cox proportional hazards model were estimated using robust SEs and considering the relatedness of relatives (full siblings, half-siblings, cousins). Additionally, odds ratios (ORs) for CAVB were calculated for traditional cardiovascular comorbidities.RESULTS: The study population (n=6 113 761) consisted of 5 382 928 full siblings, 1 266 391 half-siblings, and 3 750 913 cousins. In total, 6442 (0.11%) unique individuals were diagnosed with CAVB. Of these, 4200 (65.2%) were males. SHRs for CAVB were 2.91 for full siblings (95% CI, 2.43-3.49), 1.51 for half-siblings (0.56-4.10), and 3.54 for cousins (1.73-7.26) of affected individuals. Age-stratified analysis showed higher risk in young individuals born from 1947 to 1986: SHR, 5.30 (3.78-7.43) for full siblings, SHR, 3.30 (1.06-10.31) for half-siblings, and SHR, 3.15 (1.39-7.17) for cousins. Similar familial HRs according to Cox proportional hazard model and ORs were obtained without any major differences. Apart from familial relationship, CAVB was associated with hypertension (OR, 1.83), diabetes (OR, 1.41), coronary heart disease (OR, 2.08), heart failure (OR, 5.01), and structural heart disease (OR, 4.59).CONCLUSIONS: Risk of CAVB among relatives of affected individuals depends on relationship degree, being strongest in young siblings. The familial association extending to third-degree relatives indicates presence of genetic components in the cause of CAVB.
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| 41. |
- Flöjt, Jessica, et al.
(författare)
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Need for preparedness – nurses’ experiences of professional development in home health care
- 2014
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Ingår i: Home Health Care Management & Practice. - : SAGE Publications. - 1084-8223 .- 1552-6739. ; 26:4, s. 223-229
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Tidskriftsartikel (refereegranskat)abstract
- Abstract Home health care faces challenges that could affect job satisfaction and quality of care. The aim of the study was to describe nurses’ experiences of competence in home health care. The study sample comprised of interviews with six nurses and was analyzed using manifest qualitative content analysis. The category “Being prepared” and subcategories “Importance of leadership strategies,” “Training promotes safety and independence,” and “Co-operation for professional development” were identified. Organizing and planning continuous learning activities at a managerial level, such as collaborations with a focus on supervision and sense of coherence (SOC) training, could develop patient safety within home health care. The results demonstrate that professionally competent nurses working in home health care environments contribute to safe working practices to meet quality care outcomes. Keywords competence, home health care, nurses, professional development, qualitative content analysis
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| 42. |
- Granstam, Sven-Olof, et al.
(författare)
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Evaluation of patients with cardiac amyloidosis using echocardiography, ECG and right heart catheterization
- 2013
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Ingår i: Amyloid. - : Informa UK Limited. - 1350-6129 .- 1744-2818. ; 20:1, s. 27-33
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Tidskriftsartikel (refereegranskat)abstract
- Aims:To characterize patients with cardiac amyloidosis using echocardiography, electrocardiogram (ECG) and right heart catheterization (RHC).Methods and results:Fourteen patients with biopsy verified light chain or transthyretin cardiac amyloidosis were included. All patients had heart failure with markedly elevated NT-proBNP. Echocardiography demonstrated biventricular hypertrophy, left atrial enlargement and normal to slightly reduced left ventricular ejection fraction. Tissue Doppler septal e´ was low and median E/e´ was high. Within 6 months RHC was performed in eight of the patients. The restrictive filling pattern demonstrated by echocardiography corresponded well to median pulmonary wedge pressure (21 mmHg). Systolic pulmonary artery pressure (SPAP) was increased, whereas cardiac output and stroke volume were seen to be decreased with both methods. ECG demonstrated: low voltage (36%), abnormal R-progression (65%), ST-T abnormalities (71%) and high incidence of fibrillation (36%). In addition, a case report following the treatment of melphalan and dexamethasone is presented with improvement of hypertrophy, SPAP, left ventricular mass and e´.Conclusion: These findings should lead to a suspicion of cardiac amyloidosis and suggest further investigation.
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| 43. |
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| 44. |
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| 45. |
- Hollman, Djana, et al.
(författare)
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District nurses’ experiences with the free-choice system in Swedish primary care
- 2014
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Ingår i: British Journal of Community Nursing. - : Mark Allen Group. - 1462-4753 .- 2052-2215. ; 19:1, s. 535-541
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Tidskriftsartikel (refereegranskat)abstract
- This article describes the experiences of district nurses regarding their work situation after the free-choice system in primary care in Sweden was implemented. The study comprised a total of 17 semi-structured narratives with district nurses. The narratives were analysed using manifest qualitative content analysis. One category, ‘being an underused resource’, and three subcategories, ‘being financially aware’, ‘being flexible’ and ‘being appealing’, were identified. A focus on economic benefit can limit the cooperation and exchange of experiences within and between different care units, which could have a negative impact on the quality of care due to competition between different care providers. Underused resources and restrictions in terms of improvement skills have an impact on job satisfaction and the working environment, and affect the quality of care as a result.
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| 46. |
- Horn, Djanda, et al.
(författare)
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Managing a stressful work environment through improved teamwork - a qualitative content analysis of nurses working environment within emergency care
- 2018
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Ingår i: International Archives of Nursing and Health Care. - 2469-5823. ; 4:4
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Tidskriftsartikel (refereegranskat)abstract
- Aim: The aim of this study was to describe nurses’ experiences of their working environment in emergency departments at a general hospital in Manila, Philippines. Background: The working environment within emergency care is complex and unpredictable and may influence patient safety. Nurses are challenged by increased patient flow, staff shortages and heavy workload. Methods: This study used a qualitative content analysis with an inductive approach based on semi-structured interviews with nine nurses at emergency departments. Results: One category, improved teamwork toward a healthy working environment, which included two subcategories, barriers to providing a high quality of care and managing a stressful work environment, describe nurses’ experiences with their work environment at emergency departments in the Philippines. Conclusion: Workload manifests through a high patient ratio and patient safety-affected prioritizations of patients, which is why basic nursing is limited. Therefore, improved teamwork built upon person-centered care is needed to increase the high quality of care as well as a healthy working environment.
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| 47. |
- Ingvarsson, Elina, et al.
(författare)
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Managing Uncertainty in Nursing – Newly Graduated Nurses’ Experiences of Introduction to Nursing Profession
- 2019
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Ingår i: International Archives of Nursing and Health Care. - : ClinMed International Library. - 2469-5823. ; 5:1, s. 1-8
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Tidskriftsartikel (refereegranskat)abstract
- Background The introduction to nursing, which is the conversion of theoretical knowledge into practice skills in complex healthcare settings, is emphasized as difficult due to patient safety. Therefore, the aim of this study was to describe newly graduated nurses' experiences of introduction to nursing in a medical department (medical, emergency) at a university hospital in western Sweden. Method A manifest qualitative content analysis with an inductive approach was used based on five semistructured interviews with newly graduated nurses who work in a medical department at Sahlgrenska University Hospital in Gothenburg, Sweden. Findings One main category was found, managing uncertainty in the nursing profession, which includes three subcategories, namely, being humble as a newly graduated nurse, being adaptable as a newly graduated nurse and being a staff member instead of a nursing student. This category and these subcategories are described in the results. Conclusion The transition from education to registered nurse is a difficult step due to the anxiety that stems from making mistakes regarding limited experience related to the demands and requirements of the job. Therefore, standardized (routines, guidelines) and individualized (experiences) introductions facilitate patient safety. Moreover, person-centeredness ensures that every nurse is a capable person with resources to use in health care, i.e. a partnership within a healthy working environment that transforms novices to experts in nursing.
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| 48. |
- Jochim, Verena, et al.
(författare)
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Nursing preceptorship, a supportive and reflective approach for promoting a healthy working environment – a multi methods design
- 2022
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Ingår i: Nordic Journal of Nursing Research. - : SAGE Publications. - 2057-1585 .- 2057-1593. ; 42:3, s. 147-157
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Tidskriftsartikel (refereegranskat)abstract
- Shortage of nurses negatively influences the working environment in hospitals, by placing extra burden on newly graduated nurses. Thus, it is important to improve the knowledge and skills of nurses to increase their confidence levels. Experienced nurses serve as role models for junior nurses. This study aimed to describe and analyze a project with a nursing preceptorship in an internal medicine ward in the eastern region of Sweden. Standards for Quality Improvement Reporting Excellence (SQUIRE 2.0) were used in the multi-method approach. Quality indicators, staff turnover, short-term absence, and annual survey were analyzed using descriptive statistics. Moreover, two focus group interviews were analyzed using qualitative content analysis. The results showed marginal improvements due to quality indicators and working environment, and decreased staff turnover and short-term absenteeism. Two factors, ‘supportive working environment’ and ‘improvement in nursing’, were identified. The study concluded that selection of nurse preceptors with expertise and interest in supportive and reflective approaches is significant for promoting a healthy working environment. Moreover, interventions such as nursing preceptorship facilitate implementation (
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| 49. |
- Kero, Tanja, et al.
(författare)
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Quantification of (11)C-PIB kinetics in cardiac amyloidosis
- 2020
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Ingår i: Journal of Nuclear Cardiology. - : Springer Science and Business Media LLC. - 1071-3581 .- 1532-6551. ; 27:3, s. 774-784
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: The purpose of this work was to determine the optimal tracer kinetic model of (11)C-PIB and to validate the use of the simplified methods retention index (RI) and standardized uptake value (SUV) for quantification of cardiac (11)C-PIB uptake in amyloidosis. METHODS AND RESULTS: Single-tissue, reversible and irreversible two-tissue models were fitted to data from seven cardiac amyloidosis patients who underwent (11)C-PIB PET scans and arterial blood sampling for measurement of blood radioactivity and metabolites. The irreversible two-tissue model (2Tirr) best described cardiac (11)C-PIB uptake. RI and SUV showed high correlation with the rate of irreversible binding (Ki) from the 2Tirr model (r(2 )=0.95 and r(2 )=0.94). Retrospective data from 10 amyloidosis patients and 5 healthy controls were analyzed using RI, SUV, as well as compartment modelling with a population-average metabolite correction. All measures were higher in amyloidosis patients than in healthy controls (p=.001), but with an overlap between groups for Ki. CONCLUSION: An irreversible two-tissue model best describes the (11)C-PIB uptake in cardiac amyloidosis. RI and SUV correlate well with Ki from the 2Tirr model. RI and SUV discriminate better between amyloidosis patients and controls than Ki based on population-average metabolite correction.
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| 50. |
- Khatami, Annelie, et al.
(författare)
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An improvement project within urological care.
- 2015
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Ingår i: International journal of health care quality assurance/MCB University Press. - 0952-6862 .- 1758-6542. ; 28:4, s. 412-422
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Tidskriftsartikel (refereegranskat)abstract
- Purpose - The purpose of this paper is to describe staff experiences in an on-going improvement project regarding patients with ureteral stones. Design/methodology/approach - A qualitative descriptive study based on eight group interviews and 48 narratives, was performed. Data were analysed using qualitative content analysis. Trustworthiness was ensured by using a well-documented improvement process method during six months. Findings - The results formed three categories: an absent comprehensive view; complexity; and vulnerability within the organisation. A holistic perspective regarding urological care at the micro-, meso- and macro-levels is needed to improve planning and caring processes. Research limitations/implications - This study includes one team (six team members, different health professionals) within the same urology department. Practical implications - Results show that staff need information, such as guidelines, and support throughout the improvement work to deliver high-quality care. Moreover, there is need for evidence-based guidelines at national level to support improvement work. Social implications – Healthcare staff need to pay attention to all team member needs to improve urological care. Organisational and managerial aspect are needed to support clear and common goals regarding healthcare improvement work. Orginality/value - Urological improvement projects, gererally, are lacking, which is why this study is important to improve nephrolithiasis patient care.
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