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1.	Svensson, Sara, 1981, et al. (author) Bone response to antimicrobial noble metal nano-coating on titanium implants 2010 In: European Association for Osseointegration (EAO), 19th annual scientific meeting, 6-9 October, Glasgow, UK. Conference paper (peer-reviewed)
2.	Svensson, Sara, 1981, et al. (author) Monocyte behavior on gold and palladium surfaces 2009 In: Abstract, 22nd European Conference on Biomaterials, Lausanne, Switzerland. ; 7-11 September Conference paper (peer-reviewed)
3.	Svensson, Sara, 1981, et al. (author) Multifunctional nanostructured noble metal coatings for medical devices 2010 In: 15th International Scientific Congress (CNIC), 28 June-1 July, Havana, Cuba. Conference paper (peer-reviewed)
4.	Svensson, Sara, 1981, et al. (author) Nanostructured noble metals on implants in vitro and in vivo 2011 In: Abstract, 4th Annual Meeting, Scandinavian Society for Biomaterials, Fiskebäckskil, Sweden. ; 21:S1, s. 50- Conference paper (peer-reviewed)
5.	Svensson, Sara, 1981, et al. (author) Osseointegration of titanium with an antimicrobial nanostructured noble metal coating 2013 In: Nanomedicine: Nanotechnology, Biology, and Medicine. - : Elsevier BV. - 1549-9634 .- 1549-9642. ; 9:7, s. 1048-1056 Journal article (peer-reviewed)abstract Nanometer scale surface features on implants and prostheses can potentially be used to enhance osseointegration and may also add further functionalities, such as infection resistance, to the implant. In this study, a nanostructured noble metal coating consisting of palladium, gold and silver, never previously used in bone applications, was applied to machined titanium screws to evaluate osseointegration after 6 and 12. weeks in rabbit tibiae and femurs. Infection resistance was confirmed by in vitro adhesion test. A qualitatively and quantitatively similar in vivo bone response was observed for the coated and uncoated control screws, using histology, histomorphometry and electron microscopy. The bone-implant interface analysis revealed an extensive bone formation and direct bone-implant contact. These results demonstrate that the nanostructured noble metal coating with antimicrobial properties promotes osseointegration and may therefore be used to add extra implant functionality in the form of increased resistance to infection without the use of antibiotics. From the Clinical Editor: The authors of this paper demonstrate that nanostructured noble metal coating of implants and prostheses used in orthopedic procedures promotes osseointegration and may be used to add extra implant functionality in the form of increased resistance to infection without the use of antibiotics.

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Type of publication: conference paper (4); journal article (1)

Type of content: peer-reviewed (5)

Author/Editor: Thomsen, Peter, 1953 (5); Lausmaa, Jukka (5); Suska, Felicia, 1974 (5); Svensson, Sara, 1981 (5); Ohrlander, Mattias (5); Rydja, Gunilla (4); show more...; Palmquist, Anders, 1 ... (3); Emanuelsson, Lena, 1 ... (3); Norlindh, Birgitta, ... (3); Karlholm, Helen (3); Trobos, Margarita, 1 ... (2); Johansson, Anna, 196 ... (2); Agheli, Hossein, 196 ... (1); Petronis, Sarunas, 1 ... (1); Persson, Linda (1); Lyvén, Benny (1); Lennerås, Maria, 198 ... (1); Bäckros, Helen (1); Rydja, Gunilla I. (1); show less...

University: University of Gothenburg (5); RISE (2); Chalmers University of Technology (1)

Language: English (5)

Research subject (UKÄ/SCB): Medical and Health Sciences (5)

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