| 1. |
|
|
| 2. |
- Carraminana, Albert, et al.
(författare)
-
Rationale and Study Design for an Individualized Perioperative Open Lung Ventilatory Strategy in Patients on One-Lung Ventilation (iPROVE-OLV)
- 2019
-
Ingår i: Journal of Cardiothoracic and Vascular Anesthesia. - : W B SAUNDERS CO-ELSEVIER INC. - 1053-0770 .- 1532-8422. ; 33:9, s. 2492-2502
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: The aim of this clinical trial is to examine whether it is possible to reduce postoperative complications using an individualized perioperative ventilatory strategy versus using a standard lung-protective ventilation strategy in patients scheduled for thoracic surgery requiring one-lung ventilation. Design: International, multicenter, prospective, randomized controlled clinical trial. Setting: A network of university hospitals. Participants: The study comprises 1,380 patients scheduled for thoracic surgery. Interventions: The individualized group will receive intraoperative recruitment maneuvers followed by individualized positive end-expiratory pressure (open lung approach) during the intraoperative period plus postoperative ventilatory support with high-flow nasal cannula, whereas the control group will be managed with conventional lung-protective ventilation. Measurements and Main Results: Individual and total number of postoperative complications, including atelectasis, pneumothorax, pleural effusion, pneumonia, acute lung injury; unplanned readmission and reintubation; length of stay and death in the critical care unit and in the hospital will be analyzed for both groups. The authors hypothesize that the intraoperative application of an open lung approach followed by an individual indication of high-flow nasal cannula in the postoperative period will reduce pulmonary complications and length of hospital stay in high-risk surgical patients. (C) 2019 Published by Elsevier Inc.
|
|
| 3. |
- Goidanich, S., et al.
(författare)
-
Effect of the environment on the metal release and corrosion behaviour of different copper-based alloys : Field exposures at 5 different test sites in Europe
- 2008
-
Ingår i: 17th International Corrosion Congress 2008. - 9781615674251 ; , s. 102-115
-
Konferensbidrag (refereegranskat)abstract
- Diffuse emissions and dispersion of metals from different sources in the society have lately received an increased concern from an environmental perspective. Large research efforts have been initiated and undertaken by the division of Corrosion Science at KTH to fill knowledge gaps on corrosion-induced metal release from external constructions and buildings. The generation of such data is of paramount importance for the on-going assessment of flows and potential adverse environmental effects caused by released metals. Generated information is also essential for an improved understanding of prevailing atmospheric corrosion processes of importance for the preservation of our cultural heritage, e.g. bronze statues exposed to the atmosphere. This paper summarizes and compares long-term metal release data from pure copper, bronze (6%wt Sn) and brass (20%wt Zn) exposed at unsheltered conditions in five European environments of significantly different climatic and pollutant conditions; three urban sites (Stockholm-Sweden, Milan-Italy and Madrid-Spain) and two marine sites (Brest-France, Cadiz-Spain). Generated data are interpreted with respect to parallel multi-analytical studies of changes in patina characteristics, corrosion rates and differences in prevailing environmental conditions.
|
|
| 4. |
|
|
| 5. |
- Marto, João Pedro, et al.
(författare)
-
Safety and Outcome of Revascularization Treatment in Patients With Acute Ischemic Stroke and COVID-19: The Global COVID-19 Stroke Registry.
- 2023
-
Ingår i: Neurology. - 1526-632X. ; 100:7
-
Tidskriftsartikel (refereegranskat)abstract
- COVID-19-related inflammation, endothelial dysfunction, and coagulopathy may increase the bleeding risk and lower the efficacy of revascularization treatments in patients with acute ischemic stroke (AIS). We aimed to evaluate the safety and outcomes of revascularization treatments in patients with AIS and COVID-19.This was a retrospective multicenter cohort study of consecutive patients with AIS receiving intravenous thrombolysis (IVT) and/or endovascular treatment (EVT) between March 2020 and June 2021 tested for severe acute respiratory syndrome coronavirus 2 infection. With a doubly robust model combining propensity score weighting and multivariate regression, we studied the association of COVID-19 with intracranial bleeding complications and clinical outcomes. Subgroup analyses were performed according to treatment groups (IVT-only and EVT).Of a total of 15,128 included patients from 105 centers, 853 (5.6%) were diagnosed with COVID-19; of those, 5,848 (38.7%) patients received IVT-only and 9,280 (61.3%) EVT (with or without IVT). Patients with COVID-19 had a higher rate of symptomatic intracerebral hemorrhage (SICH) (adjusted OR 1.53; 95% CI 1.16-2.01), symptomatic subarachnoid hemorrhage (SSAH) (OR 1.80; 95% CI 1.20-2.69), SICH and/or SSAH combined (OR 1.56; 95% CI 1.23-1.99), 24-hour mortality (OR 2.47; 95% CI 1.58-3.86), and 3-month mortality (OR 1.88; 95% CI 1.52-2.33). Patients with COVID-19 also had an unfavorable shift in the distribution of the modified Rankin score at 3 months (OR 1.42; 95% CI 1.26-1.60).Patients with AIS and COVID-19 showed higher rates of intracranial bleeding complications and worse clinical outcomes after revascularization treatments than contemporaneous non-COVID-19 patients receiving treatment. Current available data do not allow direct conclusions to be drawn on the effectiveness of revascularization treatments in patients with COVID-19 or to establish different treatment recommendations in this subgroup of patients with ischemic stroke. Our findings can be taken into consideration for treatment decisions, patient monitoring, and establishing prognosis.The study was registered under ClinicalTrials.gov identifier NCT04895462.
|
|
| 6. |
- Holguín-Veras, J, et al.
(författare)
-
Public Sector Freight Interventions in Metropolitan Areas II: Pricing, Logistics, and Demand Management
- 2014
-
Ingår i: Transportation Research Board 93rd Annual Meeting, January 12-16 2014. Washington, D.C.. ; :14-0837
-
Konferensbidrag (refereegranskat)abstract
- The second in a series of two, this paper presents the results from a comprehensive survey of the various interventions that the public sector could employ to increase the net social benefits of freight activity in metropolitan areas. In this paper, the strategies concerning: pricing, incentives, and taxation; logistical management; and freight demand/land use management are discussed along with an outline for identification of potential interventions that could be of use to address a given freight issue.
|
|
| 7. |
- Holguín-Veras, J., et al.
(författare)
-
The New York city off-hour delivery program: A business and community-friendly sustainability program
- 2018
-
Ingår i: Interfaces. - : Institute for Operations Research and the Management Sciences (INFORMS). - 0092-2102 .- 1526-551X. ; 48:1, s. 70-86
-
Tidskriftsartikel (refereegranskat)abstract
- The New York City Off-Hour Delivery (NYC OHD) program is the work of a private-public-academic partnership - A collaborative effort of leading private-sector groups and companies, public-sector agencies led by the New York City Department of Transportation, and research partners led by Rensselaer Polytechnic Institute. The efforts of this partnership have induced more than 400 commercial establishments in NYC to accept OHD without supervision. The economic benefits are considerable: The carriers have reduced operational costs and parking fines by 45 percent; the receivers enjoy more reliable deliveries, enabling them to reduce inventory levels; the truck drivers have less stress, shorter work hours, and easier deliveries and parking; the delivery trucks produce 55-67 percent less emissions than they would during regular-hour deliveries, for a net reduction of 2.5 million tons of CO2 per year; and citizens' quality of life increases as a result of reduced conflicts between delivery trucks, cars, bicycles, and pedestrians, and through the use of low-noise delivery practices and technologies that minimize the impacts of noise. The total economic benefits exceed $20 million per year. The success of the OHD program is due largely to the policy design at its core, made possible with the behavioral microsimulation. This unique optimization-simulation system incorporates the research conducted into an operations research/management science tool that assesses the effectiveness of alternative policy designs. This enabled the successful implementation of the project within the most complex urban environment in the United States.
|
|
| 8. |
|
|
| 9. |
- Chang, Tingru, et al.
(författare)
-
The role of Sn on the long-term atmospheric corrosion of binary Cu-Sn bronze alloys in architecture
- 2019
-
Ingår i: Corrosion Science. - : Elsevier Ltd. - 0010-938X .- 1879-0496. ; 149, s. 54-67
-
Tidskriftsartikel (refereegranskat)abstract
- The role of Sn on the atmospheric corrosion performance of binary Cu-Sn bronze alloys (4–6 wt.% Sn) compared with Cu metal used in outdoor architecture is elucidated in terms of microstructure, native surface oxide composition, patina evolution, corrosion rates, appearance and metal release. Results are presented for non-exposed surfaces and surfaces exposed at different urban and marine sites in Europe up to 5 years and based on multi-analytical findings from microscopic, spectroscopic, electrochemical and chemical investigations. Alloying influenced the corrosion, aesthetic appearance and patina evolution, differently for urban and marine sites, whereas no effects were observed on the release pattern. © 2019 The Authors
|
|
