| 1. |
- Semb, Gunvor, et al.
(författare)
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A Scandcleft randomised trials of primary surgery for unilateral cleft lip and palate: 1. Planning and management.
- 2017
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Ingår i: Journal of Plastic Surgery and Hand Surgery. - : Taylor & Francis. - 2000-656X .- 2000-6764. ; 51:1, s. 2-13
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIMS: Longstanding uncertainty surrounds the selection of surgical protocols for the closure of unilateral cleft lip and palate, and randomised trials have only rarely been performed. This paper is an introduction to three randomised trials of primary surgery for children born with complete unilateral cleft lip and palate (UCLP). It presents the protocol developed for the trials in CONSORT format, and describes the management structure that was developed to achieve the long-term engagement and commitment required to complete the project.METHOD: Ten established national or regional cleft centres participated. Lip and soft palate closure at 3-4 months, and hard palate closure at 12 months served as a common method in each trial. Trial 1 compared this with hard palate closure at 36 months. Trial 2 compared it with lip closure at 3-4 months and hard and soft palate closure at 12 months. Trial 3 compared it with lip and hard palate closure at 3-4 months and soft palate closure at 12 months. The primary outcomes were speech and dentofacial development, with a series of perioperative and longer-term secondary outcomes.RESULTS: Recruitment of 448 infants took place over a 9-year period, with 99.8% subsequent retention at 5 years.CONCLUSION: The series of reports that follow this introductory paper include comparisons at age 5 of surgical outcomes, speech outcomes, measures of dentofacial development and appearance, and parental satisfaction. The outcomes recorded and the numbers analysed for each outcome and time point are described in the series.TRIAL REGISTRATION: ISRCTN29932826.
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| 2. |
- Aralikatte, Rahul, et al.
(författare)
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How far can we get with one GPU in 100 hours? CoAStaL at MultiIndicMT Shared Task
- 2021
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Ingår i: Proceedings of the 8th Workshop on Asian Translation (WAT2021). - Stroudsburg, PA, USA : Association for Computational Linguistics. ; , s. 205-211
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Konferensbidrag (refereegranskat)abstract
- This work shows that competitive translation results can be obtained in a constrained setting by incorporating the latest advances in memory and compute optimization. We train and evaluate large multilingual translation models using a single GPU for a maximum of 100 hours and get within 4-5 BLEU points of the top submission on the leaderboard. We also benchmark standard baselines on the PMI corpus and re-discover well-known shortcomings of translation systems and metrics.
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| 3. |
- Bollmann, Marcel, et al.
(författare)
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Error Analysis and the Role of Morphology
- 2021
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Ingår i: Proceedings of the 16th Conference of the European Chapter of the Association for Computational Linguistics. - Stroudsburg, PA, USA : Association for Computational Linguistics. ; , s. 1887-1900
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Konferensbidrag (refereegranskat)abstract
- We evaluate two common conjectures in error analysis of NLP models: (i) Morphology is predictive of errors; and (ii) the importance of morphology increases with the morphological complexity of a language. We show across four different tasks and up to 57 languages that of these conjectures, somewhat surprisingly, only (i) is true. Using morphological features does improve error prediction across tasks; however, this effect is less pronounced with morphologically complex languages. We speculate this is because morphology is more discriminative in morphologically simple languages. Across all four tasks, case and gender are the morphological features most predictive of error.
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| 4. |
- Bollmann, Marcel, et al.
(författare)
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Few-Shot and Zero-Shot Learning for Historical Text Normalization
- 2019
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Ingår i: Proceedings of the 2nd Workshop on Deep Learning Approaches for Low-Resource NLP (DeepLo 2019). - Stroudsburg, PA, USA : Association for Computational Linguistics. ; , s. 104-114
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Konferensbidrag (refereegranskat)abstract
- Historical text normalization often relies on small training datasets. Recent work has shown that multi-task learning can lead to significant improvements by exploiting synergies with related datasets, but there has been no systematic study of different multi-task learning architectures. This paper evaluates 63 multi-task learning configurations for sequence-to-sequence-based historical text normalization across ten datasets from eight languages, using autoencoding, grapheme-to-phoneme mapping, and lemmatization as auxiliary tasks. We observe consistent, significant improvements across languages when training data for the target task is limited, but minimal or no improvements when training data is abundant. We also show that zero-shot learning outperforms the simple, but relatively strong, identity baseline.
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| 5. |
- Bollmann, Marcel, et al.
(författare)
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Moses and the Character-Based Random Babbling Baseline: CoAStaL at AmericasNLP 2021 Shared Task
- 2021
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Ingår i: Proceedings of the First Workshop on Natural Language Processing for Indigenous Languages of the Americas. - Stroudsburg, PA, USA : Association for Computational Linguistics. ; , s. 248-254
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Konferensbidrag (refereegranskat)abstract
- We evaluated a range of neural machine translation techniques developed specifically for low-resource scenarios. Unsuccessfully. In the end, we submitted two runs: (i) a standard phrase-based model, and (ii) a random babbling baseline using character trigrams. We found that it was surprisingly hard to beat (i), in spite of this model being, in theory, a bad fit for polysynthetic languages; and more interestingly, that (ii) was better than several of the submitted systems, highlighting how difficult low-resource machine translation for polysynthetic languages is.
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| 6. |
- de Lhoneux, Miryam, 1990-, et al.
(författare)
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Parameter sharing between dependency parsers for related languages
- 2018
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Ingår i: Proceedings of the 2018 Conference on Empirical Methods in Natural Language Processing. - Brussels : Association for Computational Linguistics. - 9781948087841 ; , s. 4992-4997
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Konferensbidrag (refereegranskat)abstract
- Previous work has suggested that parameter sharing between transition-based neural dependency parsers for related languages can lead to better performance, but there is no consensus on what parameters to share. We present an evaluation of 27 different parameter sharing strategies across 10 languages, representing five pairs of related languages, each pair from a different language family. We find that sharing transition classifier parameters always helps, whereas the usefulness of sharing word and/or character LSTM parameters varies. Based on this result, we propose an architecture where the transition classifier is shared, and the sharing of word and character parameters is controlled by a parameter that can be tuned on validation data. This model is linguistically motivated and obtains significant improvements over a mono-lingually trained baseline. We also find that sharing transition classifier parameters helps when training a parser on unrelated language pairs, but we find that, in the case of unrelated languages, sharing too many parameters does not help.
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| 7. |
- Fetahi, Egzona, et al.
(författare)
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Estimating the Effect of Motivational Interventions in Patients with Eating Disorders : A Systematic Review and Meta-Analysis
- 2022
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Ingår i: Journal of Personalized Medicine. - : MDPI. - 2075-4426. ; 12:4
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Forskningsöversikt (refereegranskat)abstract
- Motivation to change behavior is seen as an important factor in achieving a better treatment effect in patients with eating disorders (ED). The aim of this systematic review was to assess whether motivational interviewing (MI) and motivational enhancement therapy (MET) might (1) increase motivation to change behavior and (2) improve eating disorder psychopathology (EDP) and body mass index (BMI) in patients with ED. To investigate this, a literature search was conducted on 9 March 2021 on four scientific databases: Cochrane, Embase (Ovid), MEDLINE (PubMed), and PsycInfo (EBSCO). A total of 2647 publications were identified and following a rigorous stepwise procedure to assess titles and abstracts and, thereafter, full texts of relevant publications, 13 studies were included in the data extraction and analyses. A few individual studies (n = 5) found a significant increase in motivation, two a decrease in ED symptoms (n = 2), while none found an effect on BMI. However, the meta-analysis of each outcome found effect sizes near zero, thereby confirming the results of previous narrative reviews that have described a lack of effect of MET/MI on motivation in ED. Since the individual studies differ substantially in design, and the outcomes were inconsistently assessed with regards to instruments and duration, the effect of MET/MI on motivation for behavioral change, ED psychopathology, and BMI is still unclear.
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| 8. |
- Hershcovich, Daniel, et al.
(författare)
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Challenges and Strategies in Cross-Cultural NLP
- 2022
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Ingår i: PROCEEDINGS OF THE 60TH ANNUAL MEETING OF THE ASSOCIATION FOR COMPUTATIONAL LINGUISTICS (ACL 2022), VOL 1. - Stroudsburg, PA, USA : Association for Computational Linguistics. - 9781955917216 ; , s. 6997-7013
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Konferensbidrag (refereegranskat)abstract
- Various efforts in the Natural Language Processing (NLP) community have been made to accommodate linguistic diversity and serve speakers of many different languages. However, it is important to acknowledge that speakers and the content they produce and require, vary not just by language, but also by culture. Although language and culture are tightly linked, there are important differences. Analogous to cross-lingual and multilingual NLP, cross-cultural and multicultural NLP considers these differences in order to better serve users of NLP systems. We propose a principled framework to frame these efforts, and survey existing and potential strategies.
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| 9. |
- Lent, Heather, et al.
(författare)
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What a Creole Wants, What a Creole Needs
- 2022
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Ingår i: LREC 2022. - : European Language Resources Association. - 9791095546726 ; , s. 6439-6449
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Konferensbidrag (refereegranskat)abstract
- In recent years, the natural language processing (NLP) community has given increased attention to the disparity of efforts directed towards high-resource languages over low-resource ones. Efforts to remedy this delta often begin with translations of existing English datasets into other languages. However, this approach ignores that different language communities have different needs. We consider a group of low-resource languages, Creole languages. Creoles are both largely absent from the NLP literature, and also often ignored by society at large due to stigma, despite these languages having sizable and vibrant communities. We demonstrate, through conversations with Creole experts and surveys of Creole-speaking communities, how the things needed from language technology can change dramatically from one language to another, even when the languages are considered to be very similar to each other, as with Creoles. We discuss the prominent themes arising from these conversations, and ultimately demonstrate that useful language technology cannot be built without involving the relevant community.
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| 10. |
- Lerche, Anders Fritz, et al.
(författare)
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Designing industrial work to be ‘just right’ to promote health – A study protocol for a goldilocks work intervention
- 2022
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Ingår i: BMC Public Health. - : BMC. - 1471-2458. ; 22
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Tidskriftsartikel (refereegranskat)abstract
- Background: The Goldilocks Work Principle expresses that productive work should be designed to promote workers’ health. We recently showed that it is feasible to develop and implement modifications to productive work that change physical behaviors (i.e. sitting, standing and being active) in a direction that may promote health among industrial workers. Therefore, the aim of the present study is to conduct a cluster randomised controlled trial investigating health effects of implementing the Goldilocks Work intervention among industrial workers. Methods: Our implementation plan consists of educating work teams, organizing implementation meetings, and providing feedback to workers. Three meetings with a preselected local workplace group will be scheduled. The first meeting educates the group to use a planning tool by which work can be planned to have ‘just right’ physical behaviors. The second and third meetings will focus on supporting implementation of the tool in daily work. An expected 28 clusters of work teams across two participating production sites will be randomized to either intervention or control group. Data collection will consist of 1) questionnaires regarding work and musculoskeletal health, 2) wearable sensor measurements of the physical behavior, and 3) assessment of general health indicators, including BMI, blood pressure, and fat percentage. The primary outcome is musculoskeletal health, measured by low back pain intensity, and secondary outcomes are 1) physical behaviors at work, 2) accumulated time in long bouts of sitting, standing, and being active and 3) perceived fatigue and energy during work. Furthermore, implementation and cost of the intervention will be evaluated based on questionnaires and data from the planning tool completed by the workers.Discussion: This study will evaluate the effectiveness and implementation of a 12- weeks Goldilocks Work intervention with the aim of improving musculoskeletal health among industrial workers. The cluster randomized controlled study design and the evaluation of the implementation, results and costs of the intervention will make it capable of contributing with valuable evidence of how productive work may be designed to promote industrial workers’ health.
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| 11. |
- Lerche, Anders Fritz, et al.
(författare)
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Development and implementation of ‘just right’ physical behavior in industrial work based on the Goldilocks Work Principle - a feasibility study
- 2021
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Ingår i: International Journal of Environmental Research and Public Health. - : MDPI. - 1661-7827 .- 1660-4601. ; 18:9
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Tidskriftsartikel (refereegranskat)abstract
- The Goldilocks Work Principle expresses that productive work should be redesigned to comprise physical behaviors of different intensities in a composition promoting workers’ health and fitness. This study is the first to assess the feasibility of redesigning work in an industrial setting according to the Goldilocks Work Principle. We recruited workers (n=20) from a brewery in Denmark, and we conducted a participatory 16-week intervention including a workshop and two consultations. The workshop aimed to support the workers in modifying their work, while the consultations assisted the eventual implementation. Feasibility was evaluated as per three aspects: 1) developing modifications of work, 2) implementing these modifications, and 3) changing physical behavior and self-reported fatigue, pain and energy. The three aspects were addressed through records completed by the workers, measurements of workers’ physical behavior and intensity during ‘control’ workdays (i.e., usual work) and ‘intervention’ workdays (i.e. modified work), and self-reported fatigue, pain and energy level following both types of workdays. Five modifications to work were developed, and three of these five modifications were implemented. To some extent, physical behavior and intensity changed as intended during ‘intervention’ workdays compared to ‘control’ workdays. Workers were also less fatigued, had less pain, and had more energy after ‘intervention’ workdays. These results suggest that it is feasible to develop and implement modified work based on the Goldilocks Work Principle among industrial workers. However, we also identified several barriers to the implementation of such modifications.
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| 12. |
- Lerche, Anders Fritz, et al.
(författare)
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Effectiveness of a Goldilocks Work intervention to promote musculoskeletal health among industrial workers – A cluster randomized controlled trial
- 2024
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Ingår i: Journal of Safety Research. - : Elsevier. - 0022-4375 .- 1879-1247.
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Tidskriftsartikel (refereegranskat)abstract
- Introduction: Industrial workers with physically demanding work have increased risk of musculoskeletal pain. The present 12-week Goldilocks Work intervention aimed to organize work among industrial workers to comprise a ‘just right’ ergonomic balance of physical behaviors (i.e., sit, stand and active) intended to promote musculoskeletal health. The paper investigates the effectiveness of the intervention in reducing low back pain after work. Methods: 83 workers across 28 workteams in a biotech organization were recruited. Workteams were randomly allocated to receive the intervention or work as usual (control). Intervention workteams implemented the Goldilocks Work planning tool to organize their work tasks towards a predefined ‘just right’ ergonomic balance (i.e., composition of 60% sitting, 30% standing, 10% active work and hourly task alternation). The primary outcome was low back pain intensity. Secondary outcomes were bodily pain, fatigue, physical exertion, productivity and energy after work measured in the survey, and composition and alternations of physical behaviors measured using wearable sensors. Results: The intervention was delivered almost as planned, with good quality and high adherence among most workteams. However, the intervention did not change physical behaviors towards the intended ‘just right’ ergonomic balance. No significant reduction in low back pain (0.07, CI 95%: -0.68; 0.82), bodily pain (0.10, CI 95%: -0.57; 0.76), tiredness (-0.53, CI 95%: -1.24; 0.19), physical exertion (-0.18, CI 95%: -0.83; 0.48), or improvement in energy (0.39, CI 95%: -1.02; 0.23) or productivity (-0.03, CI 95%: -0.77; 0.72) were found. Conclusion: This Goldilocks Work intervention did not promote musculoskeletal health among industrial workers, and did not change physical behaviors as intended. Thus, more research is needed into implementation strategies to change physical behaviors during productive work towards an evidence-based ‘just right’ ergonomic balance.
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| 13. |
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| 14. |
- Olsen, Henrik Palmer, et al.
(författare)
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Re-framing case law citation prediction from a paragraph perspective
- 2023
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Ingår i: Legal knowledge and information systems. - : IOS Press. - 9781643684727 - 9781643684734 ; , s. 323-328
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Konferensbidrag (refereegranskat)abstract
- Case law citation prediction, i.e., predicting what historical cases are relevant for your current case, can assist legal discovery and decision-making, but legal documents are long, and often only parts of them are relevant for a particular use case. We therefore reframe case law citation prediction as a paragraph-to-paragraph citation task, introduce a new dataset, and train and evaluate new models. We also evaluate our models qualitatively. Our resources provide a first step toward discovering citation patterns and modeling legal rules in EU law from precedent documents.
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| 15. |
- Priskorn, Lærke, et al.
(författare)
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RUBIC (ReproUnion Biobank and Infertility Cohort) : A binational clinical foundation to study risk factors, life course, and treatment of infertility and infertility-related morbidity
- 2021
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Ingår i: Andrology. - : Wiley. - 2047-2919 .- 2047-2927. ; 9:6, s. 1828-1842
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Tidskriftsartikel (refereegranskat)abstract
- Background: Infertility affects 15%–25% of all couples during their reproductive life span. It is a significant societal and public health problem with potential psychological, social, and economic consequences. Furthermore, infertility has been linked to adverse long-term health outcomes. Despite the advanced diagnostic and therapeutic techniques available, approximately 30% of infertile couples do not obtain a live birth after fertility treatment. For these couples, there are no further options to increase their chances of a successful pregnancy and live birth. Objectives: Three overall questions will be studied: (1) What are the risk factors and natural life courses of infertility, early embryonic loss, and adverse pregnancy outcomes? (2) Can we develop new diagnostic and prognostic biomarkers for fecundity and treatment success? And (3) what are the health characteristics of women and men in infertile couples at the time of fertility treatment and during long-term follow-up?. Material and Methods: ReproUnion Biobank and Infertility Cohort (RUBIC) is established as an add-on to the routine fertility management at Copenhagen University Hospital Departments in the Capital Region of Denmark and Reproductive Medicine Centre at Skåne University Hospital in Sweden. The aim is to include a total of 5000 couples equally distributed between Denmark and Sweden. The first patients were enrolled in June 2020. All eligible infertile couples are prospectively asked to participate in the project. Participants complete an extensive questionnaire and undergo a physical examination and collection of biospecimens (blood, urine, hair, saliva, rectal swabs, feces, semen, endometrial biopsies, and vaginal swabs). After the cohort is established, the couples will be linked to the Danish and Swedish national registers to obtain information on parental, perinatal, childhood, and adult life histories, including disease and medication history. This will enable us to understand the causes of infertility and identify novel therapeutic options for this important societal problem.
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| 16. |
- Ravishankar, Vinit, et al.
(författare)
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Attention Can Reflect Syntactic Structure (If You Let It)
- 2021
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Ingår i: Proceedings of the 16th Conference of the European Chapter of the Association for Computational Linguistics. - Stroudsburg, PA, USA : Association for Computational Linguistics. - 9781954085022 ; , s. 3031-3045
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Konferensbidrag (refereegranskat)abstract
- Since the popularization of the Transformer as a general-purpose feature encoder for NLP, many studies have attempted to decode linguistic structure from its novel multi-head attention mechanism. However, much of such work focused almost exclusively on English - a language with rigid word order and a lack of inflectional morphology. In this study, we present decoding experiments for multilingual BERT across 18 languages in order to test the generalizability of the claim that dependency syntax is reflected in attention patterns. We show that full trees can be decoded above baseline accuracy from single attention heads, and that individual relations are often tracked by the same heads across languages. Furthermore, in an attempt to address recent debates about the status of attention as an explanatory mechanism, we experiment with fine-tuning mBERT on a supervised parsing objective while freezing different series of parameters. Interestingly, in steering the objective to learn explicit linguistic structure, we find much of the same structure represented in the resulting attention patterns, with interesting differences with respect to which parameters are frozen.
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| 17. |
- Sorensen, Per Soelberg, et al.
(författare)
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NORdic trial of oral Methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis (NORMIMS study) : a randomised, placebo-controlled trial
- 2009
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Ingår i: Lancet Neurology. - 1474-4422 .- 1474-4465. ; 8:6, s. 519-529
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Treatment of relapsing-remitting multiple sclerosis with interferon beta is only partly effective, and new more effective and safe strategies are needed. Our aim was to assess the efficacy of oral methylprednisolone as an add-on therapy to subcutaneous interferon beta-1a to reduce the yearly relapse rate in patients with relapsing-remitting multiple sclerosis. METHODS: NORMIMS (NORdic trial of oral Methylprednisolone as add-on therapy to Interferon beta-1a for treatment of relapsing-remitting Multiple Sclerosis) was a randomised, placebo-controlled trial done in 29 neurology departments in Denmark, Norway, Sweden, and Finland. We enrolled outpatients with relapsing-remitting multiple sclerosis who had had at least one relapse within the previous 12 months despite subcutaneous interferon beta-1a treatment (44 microg three times per week). We randomly allocated patients by computer to add-on therapy of either 200 mg methylprednisolone or matching placebo, both given orally on 5 consecutive days every 4 weeks for at least 96 weeks. The primary outcome measure was mean yearly relapse rate. Primary analyses were by intention to treat. This trial is registered, number ISRCTN16202527. FINDINGS: 66 patients were assigned to interferon beta and oral methylprednisolone and 64 were assigned to interferon beta and placebo. A high proportion of patients withdrew from the study before week 96 (26% [17 of 66] on methylprednisolone vs 17% [11 of 64] on placebo). The mean yearly relapse rate was 0.22 for methylprednisolone compared with 0.59 for placebo (62% reduction, 95% CI 39-77%; p<0.0001). Sleep disturbance and neurological and psychiatric symptoms were the most frequent adverse events recorded in the methylprednisolone group. Bone mineral density had not changed after 96 weeks. INTERPRETATION: Oral methylprednisolone given in pulses every 4 weeks as an add-on therapy to subcutaneous interferon beta-1a in patients with relapsing-remitting multiple sclerosis leads to a significant reduction in relapse rate. However, because of the small number of patients and the high dropout rate, these findings need to be corroborated in larger cohorts.
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| 18. |
- Søgaard, Anders, et al.
(författare)
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Nightmare at test time : How punctuation prevents parsers from generalizing
- 2018
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Ingår i: Proceedings of the 2018 EMNLP Workshop BlackboxNLP. - Brussels : Association for Computational Linguistics. ; , s. 25-29
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Konferensbidrag (refereegranskat)abstract
- Punctuation is a strong indicator of syntactic structure, and parsers trained on text with punctuation often rely heavily on this signal. Punctuation is a diversion, however, since human language processing does not rely on punctuation to the same extent, and in informal texts, we therefore often leave out punctuation. We also use punctuation ungrammatically for emphatic or creative purposes, or simply by mistake. We show that (a) dependency parsers are sensitive to both absence of punctuation and to alternative uses; (b) neural parsers tend to be more sensitive than vintage parsers; (c) training neural parsers without punctuation outperforms all out-of-the-box parsers across all scenarios where punctuation departs from standard punctuation. Our main experiments are on synthetically corrupted data to study the effect of punctuation in isolation and avoid potential confounds, but we also show effects on out-of-domain data.
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