SwePub - sökning: WFRF:(Sandberg Karin)

Numrering	Referens	Omslagsbild	Hitta
1.	Ahlqvist, Karin, et al. (författare) Rebell eller underleverantör : - på spaning efter diakoni i vår tid 2018. - 1 Ingår i: Som en rörelse : på spaning efter diakoni i vår tid. - 9789152637586 ; , s. 57-64 Bokkapitel (populärvet., debatt m.m.)
2.	Barman, Malin, 1983, et al. (författare) Nutritional impact on Immunological maturation during Childhood in relation to the Environment (NICE): a prospective birth cohort in northern Sweden 2018 Ingår i: BMJ Open. - : BMJ. - 2044-6055 .- 2044-6055. ; 8:10 Tidskriftsartikel (refereegranskat)abstract © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. INTRODUCTION: Prenatal and neonatal environmental factors, such as nutrition, microbes and toxicants, may affect health throughout life. Many diseases, such as allergy and impaired child development, may be programmed already in utero or during early infancy. Birth cohorts are important tools to study associations between early life exposure and disease risk. Here, we describe the study protocol of the prospective birth cohort, 'Nutritional impact on Immunological maturation during Childhood in relation to the Environment' (NICE). The primary aim of the NICE cohort is to clarify the effect of key environmental exposures-diet, microbes and environmental toxicants-during pregnancy and early childhood, on the maturation of the infant's immune system, including initiation of sensitisation and allergy as well as some secondary outcomes: infant growth, obesity, neurological development and oral health.METHODS AND ANALYSIS: The NICE cohort will recruit about 650 families during mid-pregnancy. The principal inclusion criterion will be planned birth at the Sunderby Hospital in the north of Sweden, during 2015-2018. Questionnaires data and biological samples will be collected at 10 time-points, from pregnancy until the children reach 4 years of age. Samples will be collected primarily from mothers and children, and from fathers. Biological samples include blood, urine, placenta, breast milk, meconium, faeces, saliva and hair. Information regarding allergic heredity, diet, socioeconomic status, lifestyle including smoking, siblings, pet ownership, etc will be collected using questionnaires. Sensitisation to common allergens will be assessed by skin prick testing and allergic disease will be diagnosed by a paediatrician at 1 and 4 years of age. At 4 years of age, the children will also be examined regarding growth, neurobehavioural and neurophysiological status and oral health.ETHICS AND DISSEMINATION: The NICE cohort has been approved by the Regional Ethical Review Board in Umeå, Sweden (2013/18-31M). Results will be disseminated through peer-reviewed journals and communicated on scientific conferences.
3.	Knowledge formation in and through music : Festschrift in honor of Cecilia K. Hultberg 2015 2015 Samlingsverk (redaktörskap) (övrigt vetenskapligt/konstnärligt)
4.	Moberg, Christina, et al. (författare) De unga gör helt rätt när de stämmer staten 2022 Ingår i: Aftonbladet. - 1103-9000. Tidskriftsartikel (populärvet., debatt m.m.)abstract 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
5.	Mukkavaara, Jani, et al. (författare) Sustainability evaluation of timber dwellings in the north of Sweden based on environmental impact and optimization of energy and cost 2020 Ingår i: Procedia Manufacturing. - : Elsevier. - 2351-9789. ; 44, s. 76-83 Tidskriftsartikel (refereegranskat)abstract Identifying design variations that strike the balance between environmental, energy and cost can be aided using multi-objective optimization. From the resulting Pareto-solutions, selecting a single optimal solution remains a challenge. Thus, research is still needed to increase the practical use of optimization for architectural, engineering and construction (AEC) practitioners. This paper presents the use of an optimization approach where the results and an environmental assessment are discussed with AEC practitioners. The method was tested in two case studies: a prestige tourist cottage and a multifamily residential building. Different superstructures, insulation materials and windows were varied for the cottage’s envelope whilst evaluating life-cycle energy and cost. In addition, the environmental impact in terms of CO2 emissions was evaluated for the initial and optimal design suggestions for the two different superstructures. For the residential building, the insulation material thickness and the windows were varied for its evaluation of life-cycle energy and cost. For the cottage, a report was written and then read by the practitioners and used as a base for future decisions. For the residential building, the results were presented orally for the practitioners. In both cases, it was possible to communicate the overarching results of the optimizations through visual plots, although future research should find ways to also explain the detailed results.
6.	Sandberg, Karin, et al. (författare) Hållbarhetsutvärdering av byggnader : Case Ripan i Kiruna 2018 Rapport (övrigt vetenskapligt/konstnärligt)abstract Sustainability includes several parameters, and these can be measured and valued in many different ways. This study focuses on balancing the various parts to achieve sustainability by minimizing energy for heating and energy to produce the materials used in the building as well as minimizing cost for material investment and cost for heating using optimization techniques. This is balanced together with the environmental impact. This report describes an initial study for sustainability optimization of a smaller building. The goal is to develop a comprehensive approach to provide a broader basis of decisions for new construction.The calculation included the building envelope (exterior walls, roof and floors), interior walls and stabilizing elements for different frames of wood (timber frame and CLT).The result from the Ripan Case shows that the timber frame design has the lowest embodied energy and operating energy, and lowest cost for investment and heating during the operating phase. The environmental impact of the timber frame design was also low.
7.	Sandberg, Karin, et al. (författare) Önskehus på Tomt 91 i nya Kiruna 2020 Rapport (övrigt vetenskapligt/konstnärligt)abstract This report describes the work with generating a proposal for a sustainable, circular and reusable house on Site number 91 in new central parts of Kiruna. New ideas have been developed and tested in collaboration between Kirunabostäder, municipality and research partners. The study includes: generative design (GD) where a software prototype has been developed to be able to generate different building volumes for Site 91 and assess social factors like solar radiation, view, variation and green spaces. A representation of neighbouring buildings was also created to allow for a better evaluation of the generated building. Compared to the earlier developed optimization method the idea with GD is to create more opportunities for interaction between Kirunabostäder, Kiruna municipality and architects.Design for disassembly and reuse was studied in a cooperating master thesis project which resulted in an architect model of a proposed building for Site 91. An environmental assessment for three different building systems was done assuming that the building will be moved and reassembled after 50 years.An inspiring attic garden and orangery has also been developed for increased wellbeing and social comfort. A playing ground based on natural building elements (e.g. unaltered trees) was also developed.Procurement and requirements that can be formulated for circularity and reuse have also been discussed.In a longer perspective, the results from the project can contribute to a more sustainable Kiruna by exemplifying choices for sustainable and circular solutions for Kiruna housing and Kiruna municipality.
8.	Allen, Marie, et al. (författare) Association of susceptibility to multiple sclerosis in Sweden with HLA class II DRB1 and DQB1 alleles 1994 Ingår i: Human Immunology. - 0198-8859 .- 1879-1166. ; 39:1, s. 41-8 Tidskriftsartikel (refereegranskat)abstract The association of MS with HLA class II alleles was studied by PCR-based typing of the DQA1, DQB1, DRB1, and DPB1 loci in 94 Swedish patients with relapses and remissions of the disease. The haplotype DRB11501-DQA10102-DQB10602 was found to be positively associated and three haplotypes were found to be negatively associated with MS. Linkage disequilibrium makes it difficult to assess whether DRB1 or DQB1 plays the primary role in the disease association, while the association with DPB1 and DQA1 appears to be secondary to that of DQB1 and DRB1. Two of the three haplotypes negatively associated with MS carry the DQB10301 allele. Also, the negatively associated DRB10401-DQA10301-DQB10301 haplotype differs from those with nonassociated DRB10401-DQA10301-DQB10302 haplotype only at DQB1. These results suggest that DQB1 alleles, as well as some DRB1 alleles, are involved in susceptibility and protection to MS. In searching for sequence motifs in the DR beta chain associated with MS susceptibility, all DRB1 alleles on haplotypes positively associated with MS, including the DRB11501, were found to encode a Val at position 86 of the DR beta chain. Also, DRB1 alleles that are negatively associated with MS all encode a Gly at position 86, suggesting that the residue at position 86 may be critical in conferring susceptibility and protection to MS. Finally, when the effect of the DRB11501 haplotype was removed there was no support for the hypothesis that MS is associated with a putative DQ-alpha beta heterodimer, encoded for by certain DQA1 and DQB1 alleles.
9.	Aminoff, Christina, 1966- (författare) Skriftspråkliga handlingar i förskoleklass och årskurs 1 2021 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract Denna avhandling handlar om skriftspråklighet i förskoleklass och årskurs 1. Syftet med avhandlingen är att bidra med kunskap om skriftspråkliga handlingar i förskoleklass och årskurs 1 och i övergången mellan de två skolformerna. I avhandlingen ingår tre förskoleklasser och fem klasser i årskurs 1. Det empiriska materialet består av observationer, fältanteckningar, stillbilder och informella samtal. Materialet har analyserats med hjälp av tematisk analys, begrepp från tidigare forskning samt begrepp från avhandlingens teoretiska utgångspunkt, det sociokulturella perspektivet. Materialet har även analyserats med inspiration från Luke och Freebodys (1997, 1999) resursmodell. Resultatet visar att när läraren och barnen arbetar med läsande och skrivande är ofta språkets form, funktion och innehåll åtskilda från varandra. Det är en bild som framträder i arbetet med exempelvis skriftens kod. Träning av kodningsfärdigheter kopplas inte till ett funktionellt läsande och skrivande, utan sker i isolerade aktiviteter. I övergången mellan skolformerna upprepas skriftspråkligt innehåll, exempelvis kan barnen göra samma eller liknande ljudanalytiska övningar i årskurs 1 som de arbetat med i förskoleklass. Det innebär att de barn som redan behärskar det som ska läras i en övning inte möts utifrån sina kunskaper och erfarenheter.
10.	Andersen, Alf, et al. (författare) Total chloride profiles in uncracked concrete exposed at Träslövsläge Marine Field : raw data from 19921997 1998 Rapport (övrigt vetenskapligt/konstnärligt)
11.	Andersen, Janice, et al. (författare) Illness Perception and Psychological Distress in Persons with Porphyria Cutanea Tarda 2016 Ingår i: Acta Dermato-Venereologica. - : Medical Journals Sweden AB. - 0001-5555 .- 1651-2057. ; 96:5, s. 674-678 Tidskriftsartikel (refereegranskat)abstract Porphyria cutanea tarda (PCT) requires long-term treatment and follow-up, although many patients experience life-long remission. The aim of this cross-sectional postal survey was to describe and investigate the association between illness perception, health complaints, self-reported symptoms and distress in persons with PCT. The participants perceived PCT as a chronic condition with high levels of personal and treatment control. Persons who reported active symptoms scored higher on perceived illness threat, total health complaints and psychological distress compared with those in remission or latent phases. However, a higher perception of illness threat and the total burden of health complaints were more closely associated with psychological distress than were perceived PCT symptoms activity. This has implications for clinical consultation; dermatologists should be attentive to symptoms activity, but also recognize that patients in remission with a high perceived illness threat and multiple health complaints might be especially vulnerable to psychological distress with regards to PCT.
12.	Andersson, Erik, 1979-, et al. (författare) Kollegialt Lärande i Örebros Skolor – KLÖS-projektet : Hur kan lärares kollegiala lärprocesser stödjas i syfte att skapa hållbara strukturer för utvecklingsarbete? 2019 Rapport (övrigt vetenskapligt/konstnärligt)abstract Projektet KLÖS har undersökt hur lärares kollegiala lärprocesser kan stödjas i syfte att skapa hållbara strukturer för utvecklingsarbete. Målet var att skapa en Örebromodell för kollegialt lärande. En avslutande reflektion kring resultatet är att etableringen av denna modell kräver ett omfattande engagemang och tar tid att få på plats. Det är vår uppfattning att ett flertal aspekter återstår att undersöka. Bland annat är det intressant att undersöka hur arbetet med det kollegiala lärandet fortskrider på pilotskolan. Frågor som är intressanta är: Vilka faktorer har betydelse för att arbetet med kollegialt lärande ska bli permanent och fungera som ett naturligt sätt att arbeta med utveckling av praktiken? Vad blir resultatet av de utvecklingsomgångar som genomförts? Hur följs detta resultat upp och leder det till bestående gynnsamma förändringar? Frågorna handlar om hållbarhet och därmed om hur projektet går från att vara ett projekt som avslutas och glöms bort till att bli ett levande verktyg för utvecklingsarbete som kan göra en verklig skillnad i och för praktiken över tid. Eftersom mycket tid och resurser används till utvecklingsarbete i skolan är det viktigt att det arbete som görs verkligen leder till en konkret och för verksamheten gynnsam förändring. Det innebär att frågan om utvecklings- arbetets hållbarhet är en av de viktigaste frågorna. Det verktyg som utvecklats i projektet och som kommit att symbolisera det kollegiala arbetet på pilotskolan är KLÖS-hjulet. Frågan om hur KLÖS-hjulet 2.0 kan utvecklas och anpassas så att det verkligen blir ett flexibelt och användbart verktyg för att stötta det kollegiala lärandet är kanske den alla viktigaste konkreta frågan. Frågor som är besläktade med frågan om hållbarhet är de som syftar till att undersöka hur det kollegiala lärandet kan bli mer robust. Till dessa hör frågor om hur lärledarens roll kan förstärkas, hur verktyg som stöttar lärares observation och analys av den egna verksamheten kan designas, hur ansvar och engagemang på alla nivåer kan förstärkas och bli synligt samt hur arbetet med kollegialt lärande kan utvärderas. Vi har under projektets gång sett hur lärare behöver stöd i arbetet med att systematiskt identifiera behov i verksamheten för att sedan utforska möjligheter att utveckla och förändra praktiken. Medverkan från forskare som ställt frågor, problematiserat och belyst olika perspektiv har i flera fall varit avgörande för hur ett utvecklingsbehov har identifierats, avgränsats och formulerats som en undersökningsbar fråga. Det är av avgörande betydelse att utvecklingsarbetet inte står och faller med denna medverkan. Verksamheten måste själv ta fram strukturer för hur lärare och lärledare får ett tillfredsställande stöd i sitt utvecklingsarbete så att de har möjlighet att göra kollegialt lärande till en naturlig del av sitt arbete där de känner sig så bekanta med KLÖS-hjulet att de själva kan ställa de frågor som krävs. Således behöver många funktioner, både centralt och lokalt samverka för att vidareutveckla och stötta kollegialt lärande för att utveckla undervisningen i Örebro skolor.
13.	Andersson, Erik, et al. (författare) Kollegialt Lärande i Örebros Skolor – KLÖS-projektet : Hur kan lärares kollegiala lärprocesser stödjas i syfte att skapa hållbara strukturer för utvecklingsarbete? 2019 Rapport (populärvet., debatt m.m.)
14.	Andersson, Karin, et al. (författare) Barns möte med naturen 2014 Ingår i: Friluftsliv i förändring. Studier från svenska upplevelselandskap. - Stockholm : Carlsson Bokförlag. - 9789173316323 ; , s. 119-136 Bokkapitel (refereegranskat)
15.	Arvidsson, Per I., et al. (författare) Open for collaboration : an academic platform for drug discovery and development at SciLifeLab 2016 Ingår i: Drug Discovery Today. - : Elsevier BV. - 1359-6446 .- 1878-5832. ; 21:10, s. 1690-1698 Forskningsöversikt (refereegranskat)abstract The Science for Life Laboratory Drug Discovery and Development (SciLifeLab DDD) platform reaches out to Swedish academia with an industry-standard infrastructure for academic drug discovery, supported by earmarked funds from the Swedish government. In this review, we describe the build-up and operation of the platform, and reflect on our first two years of operation, with the ambition to share learnings and best practice with academic drug discovery centers globally. We also discuss how the Swedish Teacher Exemption Law, an internationally unique aspect of the innovation system, has shaped the operation. Furthermore, we address how this investment in infrastructure and expertise can be utilized to facilitate international collaboration between academia and industry in the best interest of those ultimately benefiting the most from translational pharmaceutical research - the patients.
16.	Aspeborg, Henrik, 1970-, et al. (författare) Vegetabile material, plants and a method of producing a plant having altered lignin properties 2008 Patent (populärvet., debatt m.m.)abstract The present invention is related to a set of genes, which when modified in plants gives altered lignin properties. The invention provides DNA construct such as a vector useful in the method of the invention. Further, the invention relates to a plant cell or plant progeny of the plants and wood produced by the plants according to the invention Lower lignin levels will result in improved saccharification for bio-refining and ethanol production and improved pulp and paper. Increased lignin levels will utilise lignin properties for energy production. The genes and DNA constructs may be used for the identification of plants having altered lignin characteristics as compared to the wild-type. According to the invention genes and DNA constructs may also be used as candidate genes in marker assisted breeding.
17.	Axelsson, Karin, et al. (författare) Entrepreneurial Learning in Education : Preschool as a Take-Off for the Entrepreneurial Self 2015 Ingår i: Journal of Education and Training. - : Macrothink Institute, Inc.. - 2330-9709. ; 2:2, s. 40-58 Tidskriftsartikel (refereegranskat)abstract Recently the phenomenon of entrepreneurship by political aspirations has entered the school setting. This is a world-wide development affecting education in practice and theory. In 2009 the Swedish Government launched a strategy stating that entrepreneurship should run like a common thread through the educational system. Since childhood is considered the ideal stage to influence attitudes towards entrepreneurship, and preschool constitutes the beginning of this publicly imposed “red thread”, this setting is of particular interest. In school practice the concept of entrepreneurship is translated into entrepreneurial learning. In this study we seek to investigate what characterises entrepreneurial learning in a preschool context according to preschool teachers by conducting both critical incident questionnaires and an in-depth interview using stimulated recall method. The empirical results suggest that entrepreneurial learning has developed the preschool teachers’ educational discussions and has affected the children’s entrepreneurial skills. Further, when analysing the material as to what supports and hinders a positive entrepreneurial learning situation, four main themes emerged: ongoing reflection, active participation, a meaningful learning situation and a tolerant atmosphere.
18.	Baliakas, Panagiotis, et al. (författare) Clinical effect of stereotyped B-cell receptor immunoglobulins in chronic lymphocytic leukaemia: a retrospective multicentre study 2014 Ingår i: The Lancet Haematology. - 2352-3026. ; 1:2, s. 74-84 Tidskriftsartikel (refereegranskat)abstract Background About 30% of cases of chronic lymphocytic leukaemia (CLL) carry quasi-identical B-cell receptor immunoglobulins and can be assigned to distinct stereotyped subsets. Although preliminary evidence suggests that B-cell receptor immunoglobulin stereotypy is relevant from a clinical viewpoint, this aspect has never been explored in a systematic manner or in a cohort of adequate size that would enable clinical conclusions to be drawn. Methods For this retrospective, multicentre study, we analysed 8593 patients with CLL for whom immunogenetic data were available. These patients were followed up in 15 academic institutions throughout Europe (in Czech Republic, Denmark, France, Greece, Italy, Netherlands, Sweden, and the UK) and the USA, and data were collected between June 1, 2012, and June 7, 2013. We retrospectively assessed the clinical implications of CLL B-cell receptor immunoglobulin stereotypy, with a particular focus on 14 major stereotyped subsets comprising cases expressing unmutated (U-CLL) or mutated (M-CLL) immunoglobulin heavy chain variable genes. The primary outcome of our analysis was time to first treatment, defined as the time between diagnosis and date of first treatment. Findings 2878 patients were assigned to a stereotyped subset, of which 1122 patients belonged to one of 14 major subsets. Stereotyped subsets showed significant differences in terms of age, sex, disease burden at diagnosis, CD38 expression, and cytogenetic aberrations of prognostic significance. Patients within a specific subset generally followed the same clinical course, whereas patients in different stereotyped subsets-despite having the same immunoglobulin heavy variable gene and displaying similar immunoglobulin mutational status-showed substantially different times to first treatment. By integrating B-cell receptor immunoglobulin stereotypy (for subsets 1, 2, and 4) into the well established Dohner cytogenetic prognostic model, we showed these, which collectively account for around 7% of all cases of CLL and represent both U-CLL and M-CLL, constituted separate clinical entities, ranging from very indolent (subset 4) to aggressive disease (subsets 1 and 2). Interpretation The molecular classification of chronic lymphocytic leukaemia based on B-cell receptor immunoglobulin stereotypy improves the Dohner hierarchical model and refines prognostication beyond immunoglobulin mutational status, with potential implications for clinical decision making, especially within prospective clinical trials.
19.	Baliakas, Panagiotis, 1977-, et al. (författare) No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy 2018 Ingår i: Haematologica. - : FERRATA STORTI FOUNDATION. - 0390-6078 .- 1592-8721. ; 103:4, s. E158-E161 Tidskriftsartikel (refereegranskat)
20.	Baliakas, Panagiotis, et al. (författare) Not all IGHV3-21 chronic lymphocytic leukemias are equal: prognostic considerations. 2015 Ingår i: Blood. - : American Society of Hematology. - 1528-0020 .- 0006-4971. ; 125:5, s. 856-859 Tidskriftsartikel (refereegranskat)abstract An unresolved issue in chronic lymphocytic leukemia (CLL) is whether IGHV3-21 gene usage, in general, or the expression of stereotyped B-cell receptor immunoglobulin defining subset #2 (IGHV3-21/IGLV3-21), in particular, determines outcome for IGHV3-21-utilizing cases. We reappraised this issue in 8593 CLL patients of whom 437 (5%) used the IGHV3-21 gene with 254/437 (58%) classified as subset #2. Within subset #2, immunoglobulin heavy variable (IGHV)-mutated cases predominated, whereas non-subset #2/IGHV3-21 was enriched for IGHV-unmutated cases (P = .002). Subset #2 exhibited significantly shorter time-to-first-treatment (TTFT) compared with non-subset #2/IGHV3-21 (22 vs 60 months, P = .001). No such difference was observed between non-subset #2/IGHV3-21 vs the remaining CLL with similar IGHV mutational status. In conclusion, IGHV3-21 CLL should not be axiomatically considered a homogeneous entity with adverse prognosis, given that only subset #2 emerges as uniformly aggressive, contrasting non-subset #2/IGVH3-21 patients whose prognosis depends on IGHV mutational status as the remaining CLL.
21.	Barman, Malin, 1983, et al. (författare) Exposure to a farm environment during pregnancy increases the proportion of arachidonic acid in the cord sera of offspring 2019 Ingår i: Nutrients. - : MDPI AG. - 2072-6643. ; 11:2 Tidskriftsartikel (refereegranskat)abstract Growing up in a farm environment is protective against allergy development. Various explanations have been put forward to explain this association. Fatty acids are regulators of immune function and the composition of fatty acids in the circulation system may affect immune development. Here, we investigate whether the fatty acid composition of cord serum differs for infants born to Farm (n = 26) or non-Farm mothers (n =29) in the FARMFLORA birth-cohort. For comparison, the levels of fatty acids in the maternal diet, serum and breast milk around 1 month post-partum were recorded. The fatty acids in the cord sera from infants born to Farm mothers had higher proportions of arachidonic acid (20:4 n-6) and adrenic acid (22:4 n-6) than those from infants born to non-Farm mothers. No differences were found for either arachidonic acid or adrenic acid in the diet, samples of the serum, or breast milk from Farm and non-Farm mothers obtained around 1 month post-partum. The arachidonic and adrenic acid levels in the cord blood were unrelated to allergy outcome for the infants. The results suggest that a farm environment may be associated with the fatty acid composition to which the fetus is exposed during pregnancy. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.
22.	Barman, Malin, 1983, et al. (författare) No association between allergy and current 25-hydroxy vitamin D in serum or vitamin D intake 2015 Ingår i: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 104:4, s. 405-413 Tidskriftsartikel (refereegranskat)abstract Aim Vitamin D may be involved in allergy development, but there is conflicting evidence. We investigated if dietary intake of vitamin D and levels of 25OHD in serum differed between allergic and nonallergic adolescents and if serum 25OHD correlated with dietary intake of vitamin D or season of blood sampling. Methods Serum 25-hydroxy vitamin D (25OHD) levels were analysed in 13-year-old subjects with atopic eczema (n = 55), respiratory allergy (n = 55) or no allergy (n = 55). Intake of fat-containing foods was assessed by food-frequency questionnaires, and total daily vitamin D intake was calculated. Logistic regression was used to adjust for gender, parental allergy and time of blood sampling. Results Subjects with atopic eczema or respiratory allergy did not differ from nonallergic controls regarding serum 25OHD levels or calculated vitamin D intake. Subjects sampled in the autumn had significantly higher levels of serum 25OHD than subjects sampled in the winter or spring. Serum 25OHD levels correlated to consumption of vitamin D-fortified lean milk (p = 0.001). Conclusion The findings suggest no association between allergy and 25OHD levels in serum or vitamin D intake in adolescents. Serum 25OHD levels correlated to intake of vitamin D-fortified lean milk.
23.	Barman, Malin, 1983, et al. (författare) Proportions of Polyunsaturated Fatty Acids in Umbilical Cord Blood at Birth Are Related to Atopic Eczema Development in the First Year of Life 2021 Ingår i: Nutrients. - : MDPI AG. - 2072-6643. ; 13:11 Tidskriftsartikel (refereegranskat)abstract Atopic eczema, the most common atopic disease in infants, may pave the way for sensitization and allergy later in childhood. Fatty acids have immune-regulating properties and may regulate skin permeability. Here we examine whether the proportions of fatty acids among the infant and maternal plasma phospholipids at birth were associated with maternal dietary intake during pregnancy and development of atopic eczema during the first year of age in the Nutritional impact on Immunological maturation during Childhood in relation to the Environment (NICE) birth cohort. Dietary data were collected with a semi-quantitative food frequency questionnaire, fatty acids were measured with GC-MS and atopic eczema was diagnosed by a pediatric allergologist at 12 months of age. We found that higher proportions of n-6 PUFAs (including arachidonic acid) but lower proportions of n-3 PUFAs (including DPA) in the infant's phospholipids at birth were associated with an increased risk of atopic eczema at 12 months of age. The n-6 and n-3 PUFAs were related to maternal intake of meat and fish, respectively. Our results suggest that prenatal exposure to unsaturated fatty acids is associated with eczema development in the infant. Maternal diet during pregnancy may partly explain the fatty acid profiles in utero.
24.	Barman, Malin, 1983, et al. (författare) Serum fatty acid profile does not reflect seafood intake in adolescents with atopic eczema. 2014 Ingår i: Acta Paediatrica, International Journal of Paediatrics. - : Wiley. - 0803-5253 .- 1651-2227. ; 103:9, s. 968-976 Tidskriftsartikel (refereegranskat)abstract AIM:Long-chain polyunsaturated fatty acids (LCPUFAs) are immunomodulatory, but their role in allergy development is controversial. We investigated whether proportions of LCPUFAs in serum phospholipids were related to allergic diagnosis, seafood intake and LCPUFA proportions in cord blood.METHODS:Serum was obtained from 148 birth cohort children at 13 years of age. Forty had atopic eczema, 53 had respiratory allergy, and 55 were nonallergic. Proportions of LCPUFAs were determined in serum phospholipids; cord blood from 128 of the individuals was previously analysed. Seafood intake was estimated using questionnaires.RESULTS:Allergic and nonallergic individuals did not differ significantly regarding individual LCPUFAs. However, arachidonic acid over docosahexaenoic acid (DHA) ratio was higher in allergic, compared with nonallergic, adolescents. In nonallergic individuals, LCPUFA proportions in cord serum and adolescent serum correlated weakly. In individuals with atopic eczema and respiratory allergy, these correlations were weak or absent. A moderate correlation between seafood intake and serum DHA was seen in nonallergic individuals and those with respiratory allergy, but not in those with atopic eczema.CONCLUSION:Serum LCPUFA pattern was similar in allergic and nonallergic adolescents. Fatty acid metabolism may be altered in atopic eczema subjects, suggested by poor correlations between fatty acid intake and serum levels.
25.	Baum, Seth D., et al. (författare) Long-term trajectories of human civilization 2019 Ingår i: Foresight. - : Emerald Group Publishing Limited. - 1463-6689 .- 1465-9832. ; 21:11, s. 53-83 Tidskriftsartikel (refereegranskat)abstract Purpose: This paper aims to formalize long-term trajectories of human civilization as a scientific and ethical field of study. The long-term trajectory of human civilization can be defined as the path that human civilization takes during the entire future time period in which human civilization could continue to exist. Design/methodology/approach: This paper focuses on four types of trajectories: status quo trajectories, in which human civilization persists in a state broadly similar to its current state into the distant future; catastrophe trajectories, in which one or more events cause significant harm to human civilization; technological transformation trajectories, in which radical technological breakthroughs put human civilization on a fundamentally different course; and astronomical trajectories, in which human civilization expands beyond its home planet and into the accessible portions of the cosmos. Findings: Status quo trajectories appear unlikely to persist into the distant future, especially in light of long-term astronomical processes. Several catastrophe, technological transformation and astronomical trajectories appear possible. Originality/value: Some current actions may be able to affect the long-term trajectory. Whether these actions should be pursued depends on a mix of empirical and ethical factors. For some ethical frameworks, these actions may be especially important to pursue.
26.	Bay, Annika, 1970-, et al. (författare) Exercise self-efficacy (ESE) in adults with congential heart disease 2017 Ingår i: European Heart Journal. - 0195-668X .- 1522-9645. ; 38:Suppl. 1 Tidskriftsartikel (refereegranskat)abstract Background: Many adults with congenital heart disease (CHD) have reduced aerobic exercise capacity and impaired muscle function. However, it is largely unknown which factors have influence on the confidence to perform exercise training, i.e. Exercise Self-Efficacy (ESE).Aims: To identify factors related to low ESE, and thus identify potential targets for rehabilitation and thereby enhance the potential for being physically active.Methods: Seventy-nine adults with CHD; simple lesions n=38 (women n=16), complex lesions n=41 (women n=17) (mean age 36.7±14.6 years) and 42 age and sex matched controls were recruited. All participants completed questionnaires on ESE, quality of life (EQ-5D), and physical activity (international physical activity questionnaire, IPAQ), and performed muscle endurance tests.Results: ESE was categorised into low (<26 points, n=24) and high (≥26 points, n=55). Patients with low ESE were older (45.2±15.4 vs. 32.6±12.5 years, p=0.002), more often had prescribed medication (67% vs. 44%, p=0.06), higher New York Heart Association functional class (NYHA) (≥ III) (25% vs. 7%, p=0.03) and performed fewer shoulder flexions (30.9±16.1 vs. 45.9±23.9, p=0.01) compared with those with high ESE. In the high ESE group, ESE did not differ from controls (33.8±3.9 vs. 33.4±6.1, p=0.74). In linear multivariate analysis age (B;-0.18, 95% CI -0.28- -0.08), smoking (B;-3.73, 95% CI -7.17- -0.28), EQ-5Dindex <1 (B;-3.33, 95% CI -6.08- -0.57) and number of shoulder flexions (B; 0.09, 95% CI 0.03–0.16) were independently associated with ESE.Conclusion: Many adults with CHD have low ESE. Rehabilitation targeting quality of life, smoking cessation and muscle training may improve ESE, and thus enhance the potential for being physically active in this population.
27.	Bay, Annika, et al. (författare) Exercise self-efficacy in adults with congenital heart disease 2018 Ingår i: International Journal of Cardiology: Heart and vasculature. - : Elsevier. - 2352-9067. ; 18, s. 7-11 Tidskriftsartikel (refereegranskat)abstract Background: Physical activity improves health, exercise tolerance and quality of life in adults with congenital heart disease (CHD), and exercise training is in most patients a high-benefit low risk intervention. However, factors that influence the confidence to perform exercise training, i.e. exercise self-efficacy (ESE), in CHD patients are virtually unknown. We aimed to identify factors related to low ESE in adults with CHD, and potential strategies for being physically active.Methods: Seventy-nine adults with CHD; 38 with simple lesions (16 women) and 41 with complex lesions (17 women) with mean age 36.7 ± 14.6 years and 42 matched controls were recruited. All participants completed questionnaires on ESE and quality of life, carried an activity monitor (Actiheart) during four consecutive days and performed muscle endurance tests.Results: ESE in patients was categorised into low, based on the lowest quartile within controls, (≤ 29 points, n = 34) and high (> 29 points, n = 45). Patients with low ESE were older (42.9 ± 15.1 vs. 32.0 ± 12.4 years, p = 0.001), had more complex lesions (65% vs. 42%, p = 0.05) more often had New York Heart Association functional class III (24% vs. 4%, p = 0.01) and performed fewer shoulder flexions (32.5 ± 15.5 vs. 47.7 ± 25.0, p = 0.001) compared with those with high ESE. In a logistic multivariate model age (OR; 1.06, 95% CI 1.02-1.10), and number of shoulder flexions (OR; 0.96, 95% CI 0.93-0.99) were associated with ESE.Conclusion: In this study we show that many adults with CHD have low ESE. Age is an important predictor of low ESE and should, therefore, be considered in counselling patients with CHD. In addition, muscle endurance training may improve ESE, and thus enhance the potential for being physically active in this population.
28.	Berggren, Göran, et al. (författare) Pilotmontage av nytt fasadelementsystem i trä - Fasaden i staden Snabb Snygg Smart 2020 Rapport (övrigt vetenskapligt/konstnärligt)abstract This report is about the evaluation of the pilot installation of a new wooden façade element system that was mounted on two four-story timber buildings. Technical solutions were evaluated, mounting time, moisture and deformations were measured, and interviews were conducted with builders on-site. The mounting started in April 2020 and was followed-up with measurements and interviews during 2020. The two buildings were built by Lindbäcks Bygg AB on Porsön in Luleå, Sweden and the developer was Lindbäcks Fastigheter AB. The façade elements were prefabricated by Lindbäcks Bygg AB in the factory at Öjebyn in Piteå Sweden. The mounting work went well, and the builders were positive about the facade system. When the builders had learned how to carry out the work, it took three minutes per façade element, which is equivalent to 0.9 m2/min. This is faster than the traditional installation of a facade on a construction site. The assembly around the windows took about 10 minutes, which is about the same time as in traditional assembly. During 8 months of measurements the average moisture content (MC) behind the façade elements was about 20% during winter (low T, high RH) and about 11% during summer. That is within expected values due to the annual variation in climate. The deformation was measured with laser scanning and gave a deviation of ±1 cm from a perfect plane, indicating a better dimensional stability than traditionally mounted wooden facades. From a working environment perspective, the assembly work was quieter as no nail guns were needed and the builders did not need to handle individual panel boards. Significantly less nails and screws were needed compared to traditional assembly. Experience from the assembly show the possibility for improvements. The construction platform was not optimal for loading elements during assembly. When the builders had gained some experience of the system, the limitation was to get the elements up quickly enough. A fast and efficient assembly requires a detailed planning in the design phase, and the elements should be numbered in a logical way and sufficient packaging needs to be secured. The promising results show the potential for a future way to manufacture and mount wooden facades. “The facade of the city Swift Stylish Smart” is a project within the strategic program Bioinnovation founded by Vinnova (Sweden’s innovation agency), Energimyndigheten (Swedish Energy Agency), Formas (A Swedish Research Council for Sustainable Development), and the industry partners.
29.	Berglund, Per, et al. (författare) Utvärdering för utveckling : KTH:s samtliga utbildningar under belysning 2011 Konferensbidrag (övrigt vetenskapligt/konstnärligt)
30.	Bhalerao, Rishikesh P, et al. (författare) Shoot-derived auxin is essential for early lateral root emergence in Arabidopsis seedlings 2002 Ingår i: The Plant Journal. - : Blackwell Publishing. - 0960-7412 .- 1365-313X. ; 29:3, s. 325-332 Tidskriftsartikel (refereegranskat)abstract Lateral root formation is profoundly affected by auxins. Here we present data which indicate that light influences the formation of indole-3-acetic acid (IAA) in germinating Arabidopsis seedlings. IAA transported from the developing leaves to the root system is detectable as a short-lived pulse in the roots and is required for the emergence of the lateral root primordia (LRP) during early seedling development. LRP emergence is inhibited by the removal of apical tissues prior to detection of the IAA pulse in the root, but this treatment has minimal effects on LRP initiation. Our results identify the first developing true leaves as the most likely source for the IAA required for the first emergence of the LRP, as removal of cotyledons has only a minor effect on LRP emergence in contrast to removal of the leaves. A basipetal IAA concentration gradient with high levels of IAA in the root tip appears to control LRP initiation, in contrast to their emergence. A significant increase in the ability of the root system to synthesize IAA is observed 10 days after germination, and this in turn is reflected in the reduced dependence of the lateral root emergence on aerial tissue-derived auxin at this stage. We propose a model for lateral root formation during early seedling development that can be divided into two phases: (i) an LRP initiation phase dependent on a root tip-localized IAA source, and (ii) an LRP emergence phase dependent on leaf-derived IAA up to 10 days after germination.
31.	Bjursell, Cecilia, et al. (författare) Ett aktivt åldrande: pensionärers syn på arbete och lärande 2014 Rapport (populärvet., debatt m.m.)
32.	Boberg, Karin, et al. (författare) Mötet kurslärare - handledare i VFU : Handledares perspektiv på handledning och samverkan 2022 Ingår i: NU2022.. Konferensbidrag (refereegranskat)
33.	Bonnier, Evelina, et al. (författare) Dressed for Success? The effects of Half-Naked Women on Economic Behavior 2018 Rapport (övrigt vetenskapligt/konstnärligt)
34.	Bonnier, Evelina, et al. (författare) Exposure to half-dressed women and economic behavior 2019 Ingår i: Journal of Economic Behavior and Organization. - : Elsevier BV. - 0167-2681 .- 1879-1751. ; 168, s. 393-418 Tidskriftsartikel (refereegranskat)abstract Images of half-dressed women are ubiquitous in advertising and popular culture. Yet little is known about the potential impacts of such images on economic decision making. We randomize 648 participants of both genders to advertising images including either women in bikini or underwear, fully dressed women, or no women, and examine the effects on risk taking, willingness to compete and math performance in a lab experiment. We find no treatment effects on any outcome measure for women. For men, our results indicate that men take more risk after having been exposed to images of half-dressed women compared to no women.
35.	Brodin, Jane, 1942-, et al. (författare) Interaction in Outdoor Play Environments. : Gender, culture and learning 2006 Rapport (populärvet., debatt m.m.)abstract The report is a result between Mälardalen University, Borås university college and Stockholm Institute of Education. Focus is on interaction in outdoor play environments.
36.	Broms, Anna, et al. (författare) A locally corrected multiblob method with hydrodynamically matched grids for the Stokes mobility problem 2023 Ingår i: Journal of Computational Physics. - : Elsevier. - 0021-9991 .- 1090-2716. ; 487, s. 112172-112172 Tidskriftsartikel (refereegranskat)abstract Inexpensive numerical methods are key to enabling simulations of systems of a large number of particles of different shapes in Stokes flow and several approximate methods have been introduced for this purpose. We study the accuracy of the multiblob method for solving the Stokes mobility problem in free space, where the 3D geometry of a particle surface is discretised with spherical blobs and the pair-wise interaction between blobs is described by the RPY-tensor. The paper aims to investigate and improve on the magnitude of the error in the solution velocities of the Stokes mobility problem using a combination of two different techniques: an optimally chosen grid of blobs and a pair-correction inspired by Stokesian dynamics. Different optimisation strategies to determine a grid with a given number of blobs are presented with the aim of matching the hydrodynamic response of a single accurately described ideal particle, alone in the fluid. It is essential to obtain small errors in this self-interaction, as they determine the basic error level in a system of well-separated particles. With an optimised grid, reasonable accuracy can be obtained even with coarse blob-resolutions of the particle surfaces. The error in the self-interaction is however sensitive to the exact choice of grid parameters and simply hand-picking a suitable geometry of blobs can lead to errors several orders of magnitude larger in size. The pair-correction is local and cheap to apply, and reduces the error for moderately separated particles and particles in close proximity. Two different types of geometries are considered: spheres and axisymmetric rods with smooth caps. The error in solutions to mobility problems is quantified for particles of varying inter-particle distances for systems containing a few particles, comparing to an accurate solution based on a second kind BIE-formulation where the quadrature error is controlled by employing quadrature by expansion (QBX).
37.	Broms, Anna, 1993- (författare) Accuracy, efficiency and robustness for rigid particle simulations in Stokes flow 2024 Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract The thesis concerns simulation techniques for systems of nano- to micro-scaled rigid particles immersed in a viscous fluid, ubiquitous in nature and industry. With negligible fluid inertia, the set of PDEs known as the Stokes equations can be used to model the hydrodynamics. For a dynamic study, the PDEs have to be solved at any given instance of time, provided the particle configuration and any non-hydrodynamic interactions. The resulting particle velocities can then be used to update the particle coordinates, and the equations repeatedly solved anew. For any simulation result of a physical system to be reliable, it is crucial to control different error contributions, with two error types here particularly in focus: those related to solving the Stokes equations and those related to the update in time.The PDEs can be recast as boundary integral equations (BIEs) that hold on the particle surfaces. Hydrodynamic interactions are challenging: they are simultaneously long-ranged and expensive to resolve both in time and space for closely interacting particles. The latter is caused by strong lubrication forces resulting from bodies in relative motion. We approach two alternative and related techniques to BIEs that allow for more cost-effective simulations, namely the rigid multiblob method and the method of fundamental solutions. The former is a regularisation technique that allows for generally shaped particles in large systems, both with and without thermal fluctuations. We make two improvements: the basic error level is tied to the discretisation and set by solving a small optimisation problem off-line for each given particle shape, and the accuracy for closely interacting particles is improved by pair-corrections. With the method of fundamental solutions, we present a technique with linear or close to linear scaling in the number of particles, depending on if a so-called resistance or mobility problem is solved. For circles and spheres, the accuracy can be controlled to a target level independently of the particle separations. This is done by the introduction of a small set of image points for every pair of particles close to contact that well manage to represent lubrication forces. In the model, particles can neither touch nor overlap, and our work on time-stepping is tied to the problem of contact avoiding. We develop a new strategy that guarantees contact free simulations in 3D, essential for studying the system of particles over long time spans. Controlled accuracy in solutions to the Stokes equations can together with robust timestepping allow for simulations that can complement physical experiments of particle systems for a better understanding of their behaviour, to drive the development in fields such as materials science, biomedical engineering and environmental engineering.
38.	Börve, Alexander, et al. (författare) Mobile teledermoscopy-there`s an app for that! 2013 Ingår i: Dermatology practical & conceptual. - : Mattioli1885. - 2160-9381. ; 3:2, s. 41-48 Tidskriftsartikel (refereegranskat)
39.	Börve, Alexander, et al. (författare) Smartphone Teledermoscopy Referrals: A Novel Process for Improved Triage of Skin Cancer Patients. 2015 Ingår i: Acta dermato-venereologica. - : Medical Journals Sweden AB. - 1651-2057 .- 0001-5555. ; 95:2, s. 186-190 Tidskriftsartikel (refereegranskat)abstract In this open, controlled, multicentre and prospective observational study, smartphone teledermoscopy referrals were sent from 20 primary healthcare centres to 2 dermatology departments for triage of skin lesions of concern using a smartphone application and a compatible digital dermoscope. The outcome for 816 patients referred via smartphone teledermoscopy was compared with 746 patients referred via the traditional paper-based system. When surgical treatment was required, the waiting time was significantly shorter using teledermoscopy for patients with melanoma, melanoma in situ, squamous cell carcinoma, squamous cell carcinoma in situ and basal cell carcinoma. Triage decisions were also more reliable with teledermoscopy and over 40% of the teledermoscopy patients could potentially have avoided face-to-face visits. Only 4 teledermoscopy referrals (0.4%) had to be excluded due to poor image quality. Smartphone teledermoscopy referrals allow for faster and more efficient management of patients with skin cancer as compared to traditional paper referrals.
40.	Camilla, Sandberg, et al. (författare) Habitual Physical Activity in Adults with Congenital Heart Disease Compared with Age- and Sex- Matched Controls 2016 Ingår i: Canadian Journal of Cardiology. - : Elsevier BV. - 0828-282X .- 1916-7075. ; 32:4, s. 547-553 Tidskriftsartikel (refereegranskat)abstract Background: Most adult patients with congenital heart disease (CHD) have reduced aerobic exercise capacity. Their habitual physical activity (PA) level is, however, less well studied. In this study habitual PA level in a cohort of adults with CHD compared to healthy age and gender matched controls was investigated.Methods: Eighty adults with CHD, classed as either “complex” (n=40) or “simple” (n=40), and 42 healthy controls were studied with a combined uniaxial accelerometer and heart rate monitor worn during 4 consecutive days. We analysed 1) the time spent during ≥ moderate/vigorous PA, 2) accelerometer counts/day and 3) to what extent the World Health Organization recommendations on PA were reached.Results: Patients with simple lesions had higher total accelerometer counts/day compared to both patients with complex lesions and controls (simple lesions; median (IQR) 107.7(63.4) vs. complex lesions; 72.8(53.5) and controls; 78.3(49.6), p≤0.001 and p=0.002). Furthermore, no differences in time spent during ≥ moderate-to-vigorous PA was found between patients and controls. In addition 46% of the patients with simple lesions, 55% of the patients with complex lesions and 44% of the controls did not reach the W.H.O.-recommended level of daily PA, but no significant differences between groups were found. There were no differences in achieving recommended PA level between patients in NYHA I vs. NYHA II+III.Conclusions: Patients with CHD follow the same PA-level pattern as the general population. Broad strategies promoting an active lifestyle are needed across the population and especially for patients with complex CHD and impaired NYHA class.
41.	Carling, Karin, et al. (författare) Vacancies in metals : From first-principles calculations to experimental data 2000 Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 85:18, s. 3862-3865 Tidskriftsartikel (refereegranskat)abstract We have revealed, and resolved, an apparent inability of density functional theory, within the local density and generalized gradient approximations, to describe vacancies in Al accurately and consistently. The shortcoming is due to electron correlation effects near electronic edges and we show how to correct for them. We find that the divacancy in Al is energetically unstable and we show that anharmonic atomic vibrations explain the non-Arrhenius temperature dependence of the vacancy concentration.
42.	Carling, Karin, et al. (författare) Vacancy concentration in Al from combined first-principles and model potential calculations 2003 Ingår i: Physical Review B, 61, 054101 (2003). Tidskriftsartikel (refereegranskat)
43.	Chaib, Mohamed, et al. (författare) Vi föds inte vid gränsen! : Motivation och hinder avseende invandrares kompetensutveckling i Norden - ett tankedokument 2003 Rapport (övrigt vetenskapligt/konstnärligt)
44.	Cristescu, Carmen, et al. (författare) Design for deconstruction and reuse of timber structures – state of the art review 2020 Rapport (övrigt vetenskapligt/konstnärligt)abstract This report is a state-of-the-art on timber construction in selected european countries and and discusses technical premises for a potential circular use of timber in building construction, focusing on Design for Deconstruction and Reuse (DfDR) in low-rise timber buildings, up to 3 storeys. It describes the historic and contemporary building techniques of timber buildings in all project countries (Sweden, Finland, Ireland, UK, Spain, Germany, Slovenia) and finds, that all of these countries have a long history of building with timber, but in most regions other materials dominated the housing output from the beginning of the 20th century. Only in the second half of the 20th century timber started gaining importance as a building material in Europe again, with light timber frame construction becoming an important construction system. From the beginning of the 21st century, innovations in the sector started transforming the construction industry. Mass timber products like CLT opened the market for high-rise timber buildings and in some countries office blocks, schools and hotels are built using timber, although the majority of timber construction remains residential. An even more important development might be the uptake of offsite construction, that makes timber construction more accurate, material efficient, fast and it reduces waste. These modern methods of construction are gaining importance in the construction sector of all partner countries and are likely to dominate the European housing output in the future. There will be some regional differences in the level of prefabrication, material choices and designs, so that any design guidelines for DfDR need to be adapted to the regional context. However, modern timber construction is not currently aligned with circular economy principles and is seldomly taking buildings endof-life-into account.Therefore, the report continues to summarise novel design concepts for deconstruction and reuse, that could be used in modern timber buildings. It outlines that the feasibility as well as the reuse potential depends on the scale of reclaimed components, where larger components and assemblies are often considered beneficial in terms of time, greenhouse gas emissions and waste production. If volumetric or planar units could be salvaged in the future, they also need to be adaptable for altered regulations or standards or alternative functions. It is further necessary that assemblies can be altered within buildings, since different building components have different life expectancies. Various examples for DfDR in buildings with the accompanying design strategies are presented. The buildings in the examples are often designed to be in one place for a limited timeframe and can be deconstructed and re-erected elsewhere without replacement of components. Key-features often include modularity of components, reversible connections, adaptability of the floor-plan and circular procurement. Even though it is evidently possible, the structural reuse of timber is not a wide-spread approach to date. Barriers to the use of reclaimed structural components are mainly a lack in demand for salvaged materials, but also prohibitive building regulations and the lack of design standards. Demolition practices play a crucial role as well and need to be considered in the design of buildings, to avoid damage to the components.Finally, the report summarises principles and guidelines for DfDR by different authors. As a generic approach an indicator system for deconstructability and reusability could be introduced. Time, Separability, Risk and Safety, Simplicity and Interchangeability are identified5as the main indicators for DfDR, that remain somewhat abstract. As opposed to using a generic indicator system, a more practical approach of assessing DfDR on an individual basis could be taken. This way specific shortcomings of the design can be addressed. But if DfDR found a wider application in the future, this approach may be too time consuming and there is a need for a more directed decision-making tool that can be used during the design phase of buildings to enhance DfDR. As the InFutUReWood project proceeds, it will examine a more granular approach to DfDR, relating it to the actual construction stages used in practice, developing a general template to be appropriated and adjusted to account for regional variations in construction. A strategic matrix is in development which will provide designers with a methodology based on relating principles, strategies and specific tactics to the typical design stages, to aid design decisions that promote DfDR.
45.	Cuapio, Angelica, et al. (författare) NK cell frequencies, function and correlates to vaccine outcome in BNT162b2 mRNA anti-SARS-CoV-2 vaccinated healthy and immunocompromised individuals 2022 Ingår i: Molecular Medicine. - : BioMed Central (BMC). - 1076-1551 .- 1528-3658. ; 28:1 Tidskriftsartikel (refereegranskat)abstract Adaptive immune responses have been studied extensively in the course of mRNA vaccination against COVID-19. Considerably fewer studies have assessed the effects on innate immune cells. Here, we characterized NK cells in healthy individuals and immunocompromised patients in the course of an anti-SARS-CoV-2 BNT162b2 mRNA prospective, open-label clinical vaccine trial. See trial registration description in notes. Results revealed preserved NK cell numbers, frequencies, subsets, phenotypes, and function as assessed through consecutive peripheral blood samplings at 0, 10, 21, and 35 days following vaccination. A positive correlation was observed between the frequency of NKG2C+ NK cells at baseline (Day 0) and anti-SARS-CoV-2 Ab titers following BNT162b2 mRNA vaccination at Day 35. The present results provide basic insights in regards to NK cells in the context of mRNA vaccination, and have relevance for future mRNA-based vaccinations against COVID-19, other viral infections, and cancer.Trial registration: The current study is based on clinical material from the COVAXID open-label, non-randomized prospective clinical trial registered at EudraCT and clinicaltrials.gov (no. 2021–000175-37). Description: https://clinicaltrials.gov/ct2/show/NCT04780659?term=2021-000175-37&draw=2&rank=1.
46.	Daerga, Per-Anders, et al. (författare) Byggsatsfönster. Utveckling av två prototypfönster 1998 Rapport (övrigt vetenskapligt/konstnärligt)abstract Den här rapporten handlar om byggsatsfönster i trä. Tyngdpunkten ligger på konstruktion och funktion, men även ekonomi och marknad ingår. Konceptet har flera tilltalande egenskaper. En byggsats är kompakt, inte lika skrymmande att transportera som fabriksmonterade fönster, vilket bör underlätta exportsatsningar. Vissa komponenter, framför allt isolerrutor men även beslag och tätningar, kan köpas på den lokala marknaden, vilket möjliggör anpassning till brukartraditionen.
47.	Dalhammar, Karin, et al. (författare) Health care utilization among patients with oesophageal and gastric cancer : the impact of initial treatment strategy and assignment of a contact nurse 2021 Ingår i: BMC Health Services Research. - : Springer Science and Business Media LLC. - 1472-6963. ; 21:1 Tidskriftsartikel (refereegranskat)abstract Background: Patients diagnosed with oesophageal and gastric cancer face a poor prognosis and numerous challenges of symptom management, lifestyle adjustments and complex treatment regimens. The multifaceted care needs and rapid disease progression reinforce the need for proactive and coherent health care. According to the national cancer strategy, providing coherent health care and palliative support is an area of priority. More knowledge is needed about health care utilization and the characteristics of the health care service in order to understand the readiness, accessibility and quality of current health care. The aim of this study was to describe individuals’ health care use from the time of treatment decision until death, and investigate the impact of the initial treatment strategy and assignment of a contact nurse (CN) on health care use among patients with oesophageal and gastric cancer. Methods: This population-based cohort study included patients who died from oesophageal and gastric cancer in Sweden during 2014–2016. Through linking data from the National Register for Oesophageal and Gastric Cancer, the National Cause of Death Register, and the National Patient Register, 2614 individuals were identified. Associations between the initial treatment strategy and CN assignment, and health care use were investigated. Adjusted incidence rate ratios (IRRs) with 95% confidence intervals (CIs) were calculated using Poisson regression. Results: Patients receiving palliative treatment and those receiving no tumour-directed treatment had a higher IRR for unplanned hospital stays and unplanned outpatient care visits compared with patients who received curative treatment. Patients receiving no tumour-directed treatment also had a lower IRR for planned hospital stays and planned outpatient care visits compared with patients given curative treatment. Compared with this latter group, patients with palliative treatment had a higher IRR for planned outpatient care visits. Patients assigned a CN had a higher IRR for unplanned hospital stays, unplanned outpatient care visits and planned outpatient care visits, compared with patients not assigned a CN. Conclusions: A palliative treatment strategy and no tumour-directed treatment were associated with higher rates of unplanned health care compared with a curative treatment strategy, suggesting that a proactive approach is imperative to ensure quality palliative care.
48.	Erlingsdottir, Gudbjörg, et al. (författare) E-hälsa - en reform utan statlig styrning 2019. - 1 Ingår i: På tal om e-hälsa. - 9789144120768 ; , s. 83-106 Bokkapitel (refereegranskat)abstract Gör en kritisk argumentationsanalys av policydokument inom ehälsa området
49.	Eskandari, Samieh, et al. (författare) Hydrochar-Amended Substrates for Production of Containerized Pine Tree Seedlings under Different Fertilization Regimes 2019 Ingår i: Agronomy. - : MDPI. - 2073-4395. ; 9:7, s. 1-17 Tidskriftsartikel (refereegranskat)abstract There is a growing body of research that recognizes the potentials of biochar application in agricultural production systems. However, little is known about the effects of biochar, especially hydrochar, on production of containerized seedlings under nursery conditions. This study aimed to test the effects of hydrochar application on growth, quality, nutrient and heavy metal contents, and mycorrhizal association of containerized pine seedlings. The hydrochar used in this study was produced through hydrothermal carbonization of paper mill biosludge at 200 °C. Two forms of hydrochar (powder and pellet) were mixed with peat at ratios of 10% and 20% (v/v) under three levels of applied commercial fertilizer (nil, half and full rates). Application of hydrochar had positive or neutral effects on shoot biomass and stem diameter compared with control seedlings (without hydrochar) under tested fertilizer levels. Analysis of the natural logarithmic response ratios (LnRR) of quality index and nutrient and heavy metal uptake revealed that application of 20% (v/v) hydrochar powder or pellet with 50% fertilizer resulted in same quality pine seedlings with similar heavy metal (Cu, Ni, Pb, Zn and Cr) and nutrient (P, K, Ca and Mg) contents as untreated seedlings supplied with 100% fertilizer. Colonization percentage by ectomycorrhizae significantly increased when either forms of hydrochar were applied at a rate of 20% under unfertilized condition. The results of this study implied that application of proper rates of hydrochar from biosludge with adjusted levels of liquid fertilizer may reduce fertilizer requirements in pine nurseries.
50.	Feiler, Adam A., et al. (författare) Adsorption and viscoelastic properties of fractionated mucin (BSM) and bovine serum albumin (BSA) studied with quartz crystal microbalance (QCM-D) 2007 Ingår i: Journal of Colloid and Interface Science. - : Elsevier BV. - 0021-9797 .- 1095-7103. ; 315:2, s. 475-481 Tidskriftsartikel (refereegranskat)abstract The adsorption profile and viscoelastic properties of bovine submaxillary gland mucin (BSM) and bovine serum albumin (BSA), extracted from a commercial mucin preparation, adsorbing to polystyrene surfaces has been studied using quartz crystal microbalance with dissipation monitoring (QCM-D). A significant difference in the adsorption properties of the different proteins was detected; with the BSA adsorbing in a flat rigid layer whilst the mucin adsorbed in a diffuse, highly viscoelastic layer. Subsequent addition of BSA to the preadsorbed mucin layer resulted in stiffening of the protein layer which was attributed to complexation of the mucin by BSA. In contrast, a preadsorbed layer of BSA prevented mucin adsorption altogether. Combined mixtures of mucin and BSA in well defined ratios revealed intermediate properties between the two separate protein species which varied systematically with the protein ratios. The results shed light on the synergistic effects of complexation of lower molecular weight biomolecular species with mucin. The possibility to selectively control protein uptake and tailor the physical properties of the adsorbed layer makes mucin an attractive option for application in biomaterial coatings.

Skapa referenser, mejla, bekava och länka

Länka till träfflistan

Träfflista för sökning "WFRF:(Sandberg Karin) "

Avgränsa träffmängd

År