| 1. |
- Bjärstig, Therese, 1978-, et al.
(författare)
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Between protocol and reality : Swedish municipal comprehensive planning
- 2018
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Ingår i: European Planning Studies. - : Informa UK Limited. - 0965-4313 .- 1469-5944. ; 26:1, s. 35-54
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Tidskriftsartikel (refereegranskat)abstract
- Spatial planning using a landscape approach has been recognized as being essential for reconciling ecological, cultural and socioeconomic dimensions in sustainable development (SuD). Although embraced as a concept, there is a lack of planning tools capable of incorporating multi-level, multifunctional and multi-sectoral perspectives, especially in a rural context. The departure point in this paper is the legal requirements for municipal comprehensive planning (MCP) in Sweden and an e-mail survey about incentives, stakeholder involvement, policy integration and implementation in MCP in all 15 Swedish mountain municipalities. The purpose of this explorative study is to examine whether MCP could be a tool in planning for SuD. Results indicate a general lack of resources and a low status of MCP that affect, and even limit, stakeholder involvement, policy integration and implementation. However, legal requirements for MCP are targeted at SuD, and municipal personnel responsible for planning appreciate the potential of MCP. Therefore, there is potential to develop the MCP into an effective landscape planning tool. To accomplish this, the status of an active planning process has to be raised, the mandate of the local planning agency has to be secured, and residents and land users have to be involved throughout the planning process.
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| 2. |
- Ahlgren, Sara, et al.
(författare)
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Evaluation of maleimide derivative of DOTA for site-specific labeling of recombinant affibody molecules
- 2008
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Ingår i: Bioconjugate chemistry. - : American Chemical Society (ACS). - 1043-1802 .- 1520-4812. ; 19:1, s. 235-243
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Tidskriftsartikel (refereegranskat)abstract
- Affibody molecules are a new class of small (7 kDa) scaffold affinity proteins, which demonstrate promising properties as agents for in vivo radionuclide targeting. The Affibody scaffold is cysteine-free and therefore independent of disulfide bonds. Thus, a single thiol group can be engineered into the protein by introduction of one cysteine. Coupling of thiol-reactive bifunctional chelators can enable site-specific labeling of recombinantly produced Affibody molecules. In this study, the use of 1,4,7,10-tetraazacyclododecane-1,4,7-tris-acetic acid-10-maleimidoethylacetamide (MMA-DOTA) for 111 In-labeling of anti-HER2 Affibody molecules His 6-Z HER2:342-Cys and Z HER2:2395-Cys has been evaluated. The introduction of a cysteine residue did not affect the affinity of the proteins, which was 29 pM for His 6-Z HER2:342-Cys and 27 pM for Z HER2:2395-Cys, comparable with 22 pM for the parental Z HER2:342. MMA-DOTA was conjugated to DTT-reduced Affibody molecules with a coupling efficiency of 93% using a 1:1 molar ratio of chelator to protein. The conjugates were labeled with 111 In to a specific radioactivity of up to 7 GBq/mmol, with preserved binding for the target HER2. In vivo, the non-His-tagged variant 111 In-[MMA-DOTA-Cys61]-Z HER2:2395-Cys demonstrated appreciably lower liver uptake than its His-tag-containing counterpart. In mice bearing HER2-expressing LS174T xenografts, 111 In-[MMA-DOTA-Cys61]-Z HER2:2395-Cys showed specific and rapid tumor localization, and rapid clearance from blood and nonspecific compartments, leading to a tumor-to-blood-ratio of 18 +/- 8 already 1 h p.i. Four hours p.i., the tumor-to-blood ratio was 138 +/- 8. Xenografts were clearly visualized already 1 h p.i.
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| 3. |
- Alakangas, Lena, et al.
(författare)
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Project: Improve Resource Efficiency and Minimize Environmental Footprint
- 2016
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Annan publikation (populärvet., debatt m.m.)abstract
- The REMinE project is organized in five work packages that comprise: detailedcharacterization and risk assessment of the mine wastes selected (WP2), identification of new processing methods for mine waste (WP3), characterization and risk assessment of the remaining residuals (WP4), outlining business opportunities and environmental impact in a conceptual model for sustainable mining (WP5). The project comprises case studies of historical mine wastes from three different European countries, namely Portugal, Romania and Sweden. The interdisciplinary research collaboration in this project is innovative in the sense that separation of minerals and extraction of metals not only are basedon technical and economic gain but also considers the environmental perspective.
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| 4. |
- Almlöv, Karin, et al.
(författare)
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MRI Lymph Node Evaluation for Prediction of Metastases in Rectal Cancer
- 2020
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Ingår i: Anticancer Research. - : International Institute of Anticancer Research. - 0250-7005 .- 1791-7530. ; 40:5, s. 2757-2763
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Tidskriftsartikel (refereegranskat)abstract
- Aim: To explore whether the size and characteristics of the largest regional lymph node in patients with rectal cancer, based on magnetic resonance imaging (MRI), following neoadjuvant therapy and before surgery, is able to identify patients at high risk of developing metachronous metastases.Patients and Methods: A retrospective case–control study with data from the Swedish Colo-Rectal Cancer Registry. Forty patients were identified with metachronous metastases (M+), and 40 patients without metastases (M0) were matched as controls.Results: Patients with M+ disease were more likely to have a regional lymph node measuring ≥5 mm than patients with M0. (87% vs. 65%, p=0.02). There was also a significant difference between the groups regarding the presence of an irregular border of the largest lymph node (68% vs. 40%, p=0.01).Conclusion: Lymph nodes measuring ≥5 mm with/without displaying irregular borders at MRI performed after neoadjuvant therapy emerged as risk factors for metachronous metastases in patients with rectal cancer. Intensified follow-up programmes may be indicated in these patients.
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| 5. |
- Altman, Maria, et al.
(författare)
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Prolonged second stage of labor is associated with low Apgar score
- 2015
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Ingår i: European Journal of Epidemiology. - Stockholm : Karolinska Institutet, Dept of Medicine, Solna. - 0393-2990 .- 1573-7284.
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Tidskriftsartikel (refereegranskat)abstract
- There is no consensus on the effects of a prolonged second stage of labor on neonatal outcomes. In this large Swedish population-based cohort study, our objective was to investigate prolonged second stage and risk of low Apgar score at 5 minutes. All nulliparous women (n= 32 796) delivering a live born singleton infant in cephalic presentation at ≥37 completed weeks after spontaneous onset of labor between 2008 and 2012 in the counties of Stockholm and Gotland were included. Data were obtained from computerized records. Exposure was time from fully retracted cervix until delivery. Logistic regression analyses were used to estimate crude and adjusted odds ratios (OR) with 95% confidence intervals (CI). Adjustments were made for maternal age, height, BMI, smoking, sex, gestational age, sex-specific birth weight for gestational age and head circumference. Epidural analgesia was included in a second model. The primary outcome measure was Apgar score at 5 minutes <7 and <4. We found that the overall rates of 5 minute Apgar score <7 and <4 were 7.0 and 1.3 per 1000 births, respectively. Compared to women with <1 hour from retracted cervix to birth, adjusted ORs of Apgar score <7 at 5 minutes generally increased with length of second stage of labor: 1-<2 hours: OR 1.78 (95% CI 1.19-2.66); 2- <3 hours: OR 1.66 (1.05-2.62); 3-<4 hours: OR 2.08 (1.29-3.35); and ≥4 hours: OR 2.71 (1.67-4.40). We conclude that prolonged second stage of labor is associated with an increased risk of low 5 minute Apgar score.
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| 6. |
- Andersson, Henrik C, et al.
(författare)
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Fiskevårdsplan 2007 - 2010 för Stockholms län
- 2007
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Fiskevårdsbehovet är stort i Stockholms län. Problemen med fiskbestånden täcker hela skalan från gäddans kraftiga beståndsnedgångar med kopplingar till storskaliga miljöproblem i Östersjön till utdikade sjöar och våtmarker iinlandet. Påverkan på länets vattendrag är omfattande. Det finns även stort behov att förbättra förvaltningen av de kommersiella fiskarterna i länet och därigenom skapa underlag för livskraftiga näringar baserade på fisk samtrekreation för länets invånare.Det statliga fiskevårdsbidraget kan omöjligt täcka dessa behov. Det är därför nödvändigt att samordna olika finansieringskällor och intressen. I fiskevårdsplanen finns en översiktlig beskrivning av målen för verksamheten samt strategier för att öka samordning och skapasynergieffekter mellan olika åtgärder. Länsstyrelsen har en ambition att Stockholms skärgård skall bli ett "särskilt fiskeområde" under den innevarande strukturmedelsperioden.För fiskevården inom ramen för det statliga fiskevårdsanslaget beräknas till ca 5,5 kronor miljoner per år. Statsbidraget utgör ca 2,3 miljoner per år. Kostnaderna för åtgärder i skärgården har inte specificerats för åren 2009 och 2010. Under 2007-2008 kommer det att genomföras en förstudie tillsammans med Fiskeriverket för att definiera detta behov på objektsnivå.Målgruppen för planen är centrala verk, kommuner, fiskets organisationer och enskilda. Förhoppningen är att det i det kommande fiskevårdsarbetet sker en ökad integrering av fiskevårdsarbetet med övriga mål för miljö- ochfiskeripolitiken samt den kommunala översiktsplaneringen.
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| 7. |
- Andersson, Jan, et al.
(författare)
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Biologiska kontrollundersökningar vid Oskarshamnsverket : Sammanfattning av resultaten tom 1995
- 1996
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Basundersökningar och kontroll av Oskarshamnsverkets påverkan på miljön har pågått sedan 1962. Undersökningarna var till en början brett upplagda, men kom efterhand att inrikta sig främst på påverkan på fiskbestånd och bottenfauna. Förekomsten av abborre har följt en ökande trend, såväl i kraftverkets närhet som i referensområdet i Kvädöfjärden. Mörten har ökat signifikant i referensområdet. Den förhöjda vattentemperaturen i kraftverkets närhet har medfört en anlockning av varmvattengynnade arter som abborre, mört och björkna och har visats ha en starkt positiv effekt på tillväxten hos dessa. Under senare år framträder tydliga indikationer på en snabbare tillväxt hos abborre även i mera måttligt påverkade områden i den omgivande skärgården. Likaså indikerar resultaten att anlockningen av karpfiskar till utsläppsområdet leder till minskad förekomst i den omgivande skärgården. Någon sådan effekt har inte observerats för abborren. Fångsterna av gulål i Hamnefjärden har ökat kraftigt under senare år, främst p g a ett lyckat resultat av utsättningar under 1980-talet.Fångstutvecklingen för strömming avviker från utvecklingen i Östersjön som helhet och tyder på en fortsatt omfattande anlockning under vinterhalvåret. Tillkomsten av den tredje reaktorn, i kombination med generellt höga vattentemperaturer, har medfört att strömmingen uppehållit sig på större djup än tidigare. Storskaliga beståndsfluktuationer samt starkare koncentration till utsläppsområdet har medfört markanta ökningar för ett flertal arter efter 1980-talets mitt. Förekomsten av torsk har dock minskat drastiskt till följd av en tillbakagång för hela östersjobeståndet.Temperaturhöjningen i recipienten har inte medfört någon anmärkningsvärd höjning av sjukdomsfrekvensen hos fisk. En parasit i ålens simblåsa, Anguillicola crassus, etablerades snabbt i närområdet i slutet av 1980-talet, men även om de höga temperaturerna gynnat dess utveckling har den på senare år också blivit vanlig i andra kustområden. Störningar på könsorganen har under senare år varit vanliga hos flera fiskarter. Problemet har främst studerats hos abborre och mört och symptomen ses som en effekt av att onormalt höga temperaturer under större delen av året leder till störningar på de processer som styr äggutvecklingen hos honan.Fångsterna i det yrkesmässiga ålfisket i kraftverkets närhet har uppvisat små förändringar sedan 1970-talet. Skillnader mellan enskilda år var dock stora. Några effekter av driften på fångstens storlek har inte kunnat påvisas.Bottenfaunasamhällena i Simpevarp och Kvädöfjärden har utvecklats likartat under en lång följd av år. Under 1990-talet inträffade dock en utarmning av samhället på den djupare lokalen vid Simpevarp, sannolikt till följd av att ökad näringstillförsel via kylvattenströmmen medfört syrebrist i sedimentet.Algsamhällena på hårda bottnar har studerats genom dykningar sedan 1989. Områdets tångtälten tillhör de rikaste i Kalmar län och har också stor utbredning i djupled. Under senare år har dock en försämring inträffat till följd av betning av ett kräftdjur, tånggråsuggan. En motsvarande uttunning av tångbältet har konstaterats på många andra platser i länet.
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| 8. |
- Andersson, Jan, et al.
(författare)
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Utslagen fiskrekrytering och sviktande fiskbestånd i Kalmar läns kustvatten
- 2000
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Undersökningar gjorda 1994-1997 i ett antal områden i Kalmarsund visade minskande bestånd av främst gädda och abborre samt en låg årsyngelproduktion vid jämförelse med tidigare studier. Observationerna stöddes av rapporter från fiskare och allmänhet och uppfattades så allvarliga, att ett tvåårigt forskningsprojekt beslutades genomföras för att dels dokumentera skadornas karaktär och geografiska utbredning, dels analyserade bakomliggande orsakerna. Projektet, som pågick under 1998-1999, omfattade ett flertal områden efter Kalmarsunds fastlandskust, ett område öster om Öland, samt några referensområden norr om sundet och ett söder därom. Inventerande provfisken och årsyngelundersökningar gjordes för att kartlägga fisksamhällets sammansättning och rekryteringen till de vuxna bestånden. Trålningar genomfördes under abborrens kläckningsperiod för att mäta tätheten av fisklarver samt undersöka deras överlevnad och tillväxt. I samband med detta gjordes insamlingar av djurplankton för att kartlägga larvernas födounderlag. Fält- och laboratorieexperiment genomfördes för att studera romutveckling, kläckning och larvöverlevnad hos gädda och abborre. Som stöd vid tolkningarna av resultaten inhämtades vattenkemiska data från den samordnade kustvattenkontrollen i Kalmar län.Tätheten av främst vuxen abborre men även gädda var mycket låg i området mellan Emån och Revsudden i sundets mitt och andelen gamla fiskar var stor. Även längre ner mot länsgränsen fanns tecken på att bestånden var negativt påverkade. På lokalen vid östra Öland var tätheterna likaså mycket låga. Inventeringen av årsyngel gav en ännu mer negativ bild. Bara ett fåtal yngel av abborre och gädda fångades i hela Kalmarsundsområdet. Även yngel av karpfiskar,strömming och stubbar förekom i lågatätheter. Något påverkade alltså fiskrekryteringen så negativt, att även de vuxna bestånden av flertalet arter reducerats. Det strandnära yngel- och småfisksamhället dominerades av spiggar, vilka förekom i högre tätheter än i referensområdena. Resultaten från de lokaler som besökts vid upprepade tillfällen visade att skadorna förvärrats med tiden.Vattenkemiska data visade, att högsalt- eller ammoniumhalt knappast kunde vara en tänkbar förklaring till den uteblivna rekryteringen. Ammoniumhalterna når inte skadliga nivåer i rekryteringsområdena, och salthalten har minskat i stället för ökat i kustområdet under de senaste 10 åren. Såväl fält- som laboratorieexperimenten gav resultat som talar emot en toxisk påverkan på föräldrafiskar eller ägg och larver. Befruktningsgrad, kläckning och larvöverlevnad vartill synes normala. Undersökning av snäckor från de områden där kläckningsförsök och rekryteringsstudier genomfördes, visade att det åtminstone detta år inte förekom larver eller cerkarier ögonsugmasken Diplostomum sp. under den känsliga period då fisklarver kan dödas av parasitangrepp. Eutrofiering har förts fram som en tänkbar orsak till den sviktande fiskrekryteringen. Närsaltsdata visar att området är övergött, och en förändrad kväve/fosforkvot antyder att primärproduktionen blivit alltmer kvävebegränsad under produktionsperioden senare år.Eutrofieringen yttrar sig som en ökning av primärproduktionen. Halterna klorofyll-a har tenderat att öka i de kustnära vattnen och bedöms som höga enligt Naturvårdsverkets bedömningsgrunder för miljökvalitet, Kust och Hav (1999). Under de senaste 4-5 åren har halterna emellertid sjunkit, vilket kan kopplas till ökat siktdjup. Utvecklingen indikerar att en större del av primärproduktionen under senare år sker i det bentiska växtsamhället. Denna utveckling ses inte i referensområdena. Även om en rik bottenvegetation normalt är positivt för fisk, kan alltför kraftig algpåväxt ha flera negativa effekter, t ex att leksubstraten försämras. En förskjutning av produktionen från pelagiska mikroalger till det bentiska systemet kan också innebära att fiskens födotillgång påverkas. Analyserna av zooplanktonproven visade tydliga avvikelser jämfört med referensmaterialen, såväl vad avser artsammansättning som täthet, och indikerar att födounderlaget försämrats för pelagiska fisklarver, t ex abborre, strömming och stubbar.Utsläppen från Mönsterås Bruk har också ansetts utgöra en möjlig förklaring. Om skadorna på fisk beror på eutrofiering, kan effekterna av brukets utsläpp ses som ett bidrag bland andra till den antropogena belastningen i området. Risken för att toxiska eller hormonellt störande ämnen i avloppsvattnet påverkat fisken måste enligt resultaten från fält och laboratorieexperimenten bedömas vara liten.Kalmarsund hyser landets tätaste skarvkolonier. Teoretiska beräkningar, baserat på uppskattningar av skarvbeståndets storlek, visar att dess konsumtion skulle kunna uppgå till den totala produktionen av stationär fisk i området vilket kan vara en viktig förklaring till de minskande tätheterna. Det finns dock observationer som talar mot skarven som den enda bakomliggande faktorn. Årsyngel utnyttjas normalt inte som föda av skarvarna, och rekryteringen försämrades inte bara för de stationära arterna abborre och gädda, utan även för stubbar och sillar vars vuxna bestånd inte påverkas lika starkt av skarv. Modellsimuleringar visar dock, att i dagens situation kan skarvpredationen effektivt motverka att bestånden återhämtar sig när, förhoppningsvis, rekryteringen åter börjar bli normal.
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| 9. |
- Arnäs, Per-Olof, 1969, et al.
(författare)
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Vi måste utbilda framtidens ingenjörer på ett nytt sätt
- 2019
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Ingår i: Ny Teknik. ; , s. 4-4
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- Hur ska vi möta en alltmer komplex samhällsutveckling när det är massproduktion av arbetskraft som premieras? Digitaliseringen kullkastar logiken i vårt utbildningssystem, skriver Per Olof Arnäs och Christian Sandström på Chalmers.
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| 10. |
- Astrauskas, Andrius, et al.
(författare)
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Distribution and abundance of young pelagic fish : monitored by hydroacoustics in two coastal areas in the SW Bothnian Sea
- 1994
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The distribution of young pelagic fish in autumn was studied by hydroacoustic techniques in two coastal areas in the SW Bothnian Sea, one exposed to cooling water from a nuclear power plant and the second a reference area free from local disturbance. Generally, herring young-of-the-year dominated among pelagic fish and often constituted over 80% of the total numbers of fish counted. Young herring were concentrated to certain parts of the studied archipelagos, predominantly to the more shallow waters and to the outer parts of the small inlets commonly occurring in these coastal areas. When comparing the results of subsequent visits in the different study areas, it was evident that the estimated densities often varied markedly between days, although the distributionpatterns did not change. This was interpreted as an effect of migrations in and out of waters too shallow to be monitored by echosounder techniques. In September young herring evidently still depends upon an access to sheltered and very shallow habitats. Abundances of herring fry were higher in the cooling water exposed area compared to the reference, supporting earlier observations on positive temperature effects on fishrecruitment at this nuclear power plant.
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| 11. |
- Basic, Carmen, 1975, et al.
(författare)
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Heart failure outcomes in low-risk patients with atrial fibrillation: a case-control study of 680 523 Swedish individuals
- 2023
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Ingår i: Esc Heart Failure. - 2055-5822. ; 10:4, s. 2281-2289
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Tidskriftsartikel (refereegranskat)abstract
- AimsKnowledge of long-term outcomes in patients with atrial fibrillation (AF) remains limited. We sought to evaluate the risk of new-onset heart failure (HF) in patients with AF and a low cardiovascular risk profile. Methods and resultsData from the Swedish National Patient Register were used to identify all patients with a first-time diagnosis of AF without underlying cardiovascular disease at baseline between 1987 and 2018. Each patient was compared with two controls without AF from the National Total Population Register. In total, 227 811 patients and 452 712 controls were included. During a mean follow-up of 9.1 (standard deviation 7.0) years, the hazard ratio (HR) for new-onset HF was 3.55 [95% confidence interval (CI) 3.51-3.60] in patients compared with controls. Women with AF (18-34 years) had HR for HF onset 24.6 (95% CI 7.59-80.0) and men HR 9.86 (95% CI 6.81-14.27). The highest risk was within 1 year in patients 18-34 years, HR 103.9 (95% CI 46.3-233.1). The incidence rate within 1 year increased from 6.2 (95% CI 4.5-8.6) per 1000 person-years in young patients (18-34 years) to 142.8 (95% CI 139.4-146.3) per 1000 person-years among older patients (>80 years). ConclusionsPatients studied had a three-fold higher risk of developing HF compared with controls. Young patients, particularly women, carry up to 100-fold increased risk to develop HF within 1 year after AF. Further studies in patients with AF and low cardiovascular risk profile are needed to prevent serious complications such as HF.
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| 12. |
- Bojmar, Linda, et al.
(författare)
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The Role of MicroRNA-200 in Progression of Human Colorectal and Breast Cancer
- 2013
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Ingår i: PLOS ONE. - : Public Library of Science. - 1932-6203. ; 8:12, s. 84815-
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Tidskriftsartikel (refereegranskat)abstract
- The role of the epithelial-mesenchymal transition (EMT) in cancer has been studied extensively in vitro, but involvement of the EMT in tumorigenesis in vivo is largely unknown. We investigated the potential of microRNAs as clinical markers and analyzed participation of the EMT-associated microRNA-200 ZEB E-cadherin pathway in cancer progression. Expression of the microRNA-200 family was quantified by real-time RT-PCR analysis of fresh-frozen and microdissected formalin-fixed paraffin-embedded primary colorectal tumors, normal colon mucosa, and matched liver metastases. MicroRNA expression was validated by in situ hybridization and after in vitro culture of the malignant cells. To assess EMT as a predictive marker, factors considered relevant in colorectal cancer were investigated in 98 primary breast tumors from a treatment-randomized study. Associations between the studied EMTmarkers were found in primary breast tumors and in colorectal liver metastases. MicroRNA-200 expression in epithelial cells was lower in malignant mucosa than in normal mucosa, and was also decreased in metastatic compared to non-metastatic colorectal cancer. Low microRNA-200 expression in colorectal liver metastases was associated with bad prognosis. In breast cancer, low levels of microRNA-200 were related to reduced survival and high expression of microRNA-200 was predictive of benefit from radiotheraphy. MicroRNA-200 was associated with ER positive status, and inversely correlated to HER2 and overactivation of the PI3K/AKT pathway, that was associated with high ZEB1 mRNA expression. Our findings suggest that the stability of microRNAs makes them suitable as clinical markers and that the EMT-related microRNA-200 - ZEB - E-cadherin signaling pathway is connected to established clinical characteristics and can give useful prognostic and treatment-predictive information in progressive breast and colorectal cancers.
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| 13. |
- Browaldh, Lars, et al.
(författare)
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Celiaki är en vanlig sjukdom som är lätt att missa
- 2014
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Ingår i: Läkartidningen. - : Swedish Medical Association. - 0023-7205 .- 1652-7518. ; 111:11, s. 484-488
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Tidskriftsartikel (refereegranskat)abstract
- Celiaki ansågs länge som en ovanlig barnsjukdom, men är en vanlig sjukdom som drabbar alla åldrar. Genomförda screeningar av normalbefolkningen visar att merparten inte fått diagnos eller behandling. Den kliniska bilden varierar: alltifrån diffusa besvär eller inga symtom alls till allvarliga gastrointestinala symtom med grav avmagring och tillväxtrubbning till följd av malabsorption. Klinisk misstanke om eller hereditet för celiaki bör föranleda analys av specifika serologiska markörer. Gastroskopi med tunntarmsbiopsi bör övervägas för att bekräfta eller utesluta diagnosen.
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| 14. |
- Calner, Mikael, et al.
(författare)
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Significance of a halysitid-heliolitid mud-facies autobiostrome from the Middle Silurian of Gotland, Sweden.
- 2000
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Ingår i: Palaios. - 1938-5323. ; 15:6, s. 509-521
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Tidskriftsartikel (refereegranskat)abstract
- A low-diversity halysitid-heliolitid autobiostrome from the Late Wenlock Halla Formation at Blåhäll 1, Gotland, indicates a brief period of particular environmental conditions. The reef is 0.3–0.5 m thick, internally without bedding structures, and had a sheet-like distribution on a low-relief soft-bottom, in marginal platform, graptolitiferous strata (height-width ratio is 1:900 in outcrop). The dominating coral species building this mud-facies biostrome were the tabulates Stelliporella cf. parvistella and Halysites laticatenatus. The rugose coral fauna is dominated by fixosessile and rhizosessile forms with well developed holdfasts, for example Dokophyllum elegantulum. Coral growth forms generally indicate high background sedimentation rates during the growth of the biostrome. Four successive stages of sea-floor development are discussed: (1) a pre-biostrome stage, (2) a pioneering community stage, (3) a climax-community stage, and (4) a post-biostrome stage. Stratigraphically, these stages show an increased carbonate-siliciclastic ratio, a decreased phosphorus content, somewhat lighter {delta}18O stable isotopes, and an increased rate of bioturbation. The climax-community stage coincides with a bloom(?) in paleocopid and metacopid ostracodes. The biostrome differs from all other Wenlock-Ludlow reefs on Gotland in its geographic and stratigraphic isolation on the seaward slope of the carbonate platform. It was the first re-appearance of a reefal stucture following the oceanic Mulde Event and associated eustasy. On a regional scale, this appearance coincided with an inferred highstand systems tract and the onset of widespread reef growth in the basin indicating that, at least, basin-regional factors controlled reef growth.
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| 15. |
- Cnattingius, Sven, et al.
(författare)
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The Swedish medical birth register during five decades : documentation of the content and quality of the register
- 2023
-
Ingår i: European Journal of Epidemiology. - : Springer. - 0393-2990 .- 1573-7284. ; 38:1, s. 109-120
-
Tidskriftsartikel (refereegranskat)abstract
- Pregnancy-related factors are important for short- and long-term health in mothers and offspring. The nationwide population-based Swedish Medical Birth Register (MBR) was established in 1973. The present study describes the content and quality of the MBR, using original MBR data, Swedish-language and international publications based on the MBR. The MBR includes around 98% of all births in Sweden. From 1982 onwards, the MBR is based on prospectively recorded information in standardized antenatal, obstetric, and neonatal records. When the mother and infant are discharged from hospital, this information is forwarded to the MBR, which is updated annually. Maternal data include information from first antenatal visit on self-reported obstetric history, infertility, diseases, medication use, cohabitation status, smoking and snuff use, self-reported height and measured weight, allowing calculation of body mass index. Birth and neonatal data include date and time of birth, mode of delivery, singleton or multiple birth, gestational age, stillbirth, birth weight, birth length, head circumference, infant sex, Apgar scores, and maternal and infant diagnoses/procedures, including neonatal care. The overall quality of the MBR is very high, owing to the semi-automated data extraction from the standardized regional electronic health records, Sweden's universal access to antenatal care, and the possibility to compare mothers and offspring to the Total Population Register in order to identify missing records. Through the unique personal identity numbers of mothers and live-born offspring, the MBR can be linked to other health registers. The Swedish MBR contains high-quality pregnancy-related information on more than 5 million births during five decades.
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| 16. |
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| 17. |
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| 18. |
- Dahlqvist Leinhard, Olof, 1978-, et al.
(författare)
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Quantifying differences in hepatic uptake of the liver specific contrast agents Gd-EOB-DTPA and Gd-BOPTA : a pilot study
- 2012
-
Ingår i: European Radiology. - : Springer Berlin/Heidelberg. - 0938-7994 .- 1432-1084. ; 22:3, s. 642-653
-
Tidskriftsartikel (refereegranskat)abstract
- Objectives To develop and evaluate a procedure for quantifying the hepatocyte-specific uptake of Gd-BOPTA and Gd-EOB-DTPA using dynamic contrast-enhanced (DCE) MRI. Methods Ten healthy volunteers were prospectively recruited and 21 patients with suspected hepatobiliary disease were retrospectively evaluated. All subjects were examined with DCE-MRI using 0.025 mmol/kg of Gd-EOB-DTPA. The healthy volunteers underwent an additional examination using 0.05 mmol/kg of Gd-BOPTA. The signal intensities (SI) of liver and spleen parenchyma were obtained from unenhanced and enhanced acquisitions. Using pharmacokinetic models of the liver and spleen, and an SI rescaling procedure, a hepatic uptake rate, K Hep, estimate was derived. The K Hep values for Gd-EOB-DTPA were then studied in relation to those for Gd-BOPTA and to a clinical classification of the patient’s hepatobiliary dysfunction. Results K Hep estimated using Gd-EOB-DTPA showed a significant Pearson correlation with K Hep estimated using Gd-BOPTA (r = 0.64; P < 0.05) in healthy subjects. Patients with impaired hepatobiliary function had significantly lower K Hep than patients with normal hepatobiliary function (K Hep = 0.09 ± 0.05 min-1 versus K Hep = 0.24 ± 0.10 min−1; P < 0.01). Conclusions A new procedure for quantifying the hepatocyte-specific uptake of T 1-enhancing contrast agent was demonstrated and used to show that impaired hepatobiliary function severely influences the hepatic uptake of Gd-EOB-DTPA. Key Points • The liver uptake of contrast agents may be measured with standard clinical MRI. • Calculation of liver contrast agent uptake is improved by considering splenic uptake. • Liver function affects the uptake of the liver-specific contrast agent Gd-EOB-DTPA. • Hepatic uptake of two contrast agents (Gd-EOB-DTPA, Gd-BOPTA) is correlated in healthy individuals. • This method can be useful for determining liver function, e.g. before hepatic surgery
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| 19. |
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| 20. |
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| 21. |
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| 22. |
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| 23. |
- Ek, Helene, et al.
(författare)
-
Integrated fish monitoring in Sweden
- 2009
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- The purpose of this report is to present a review and an evaluation of thestrategy of integrated fish monitoring included in the Swedish national marinemonitoring programme. As a background to the review an assessment is madeof some of the long-term changes observed in monitoring.The project is financed by the Environment Protection Agency (Contract no.212 0326) and the Faculty of Science, Göteborg University. The project leader isProf. Åke Larsson. Dr Olof Sandström, Skärgårdsutveckling SKUTAB AB, is contractedas external reviewer of the programme. Subproject leaders and participantsin the programme have contributed with results and comments on thepaper.
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| 24. |
- Eliasson, Eva, 1960-
(författare)
-
Metod, personlighet och forskning : Kontinuitet och förändring i vårdlärarutbildarnas kunskapskultur 1958-1999
- 2009
-
Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This dissertation focuses on continuity and change in a local knowledge culture, the nursing teacher education in Stockholm, during the years between 1958 and 1999, with a strong emphasis on conceptions of knowledge and learning. Concepts of analysis come from Basil Bernstein, Ludwik Fleck, Reinhart Koselleck and gender theory. The study is based on archived documents and interviews with nursing teacher educators. The results show continuity as well as change of the knowledge culture. The first period, 1958-1974, shows continuity in relation to the space of experience. Methodical knowledge is important. The second time period, 1975-1978, is characterized by great changes, starting with a distinct break when prior conceptions and values are discarded. The focus on important, external knowledge of the earlier period is replaced by the conception that the human being and her inner abilities and characteristics are the most important resources for the profession. Conceptions and values are not completely abandoned during the last time period, 1979-1999. Values connected to personality development remain, but new values appear as a consequence of state governance towards research basis. The spirit of time, new co-workers, changed state governance, the ideological characteristics of values as well as a female dominance within the education allow an understanding of the great change in conceptions and values in the middle of the 1970’s. A stable staff of nursing teacher educators, the specific ideological and gender coded features of the values and a traditional distinctiveness and separation from other teacher education programs allow an understanding of the stability of the personality development element. The male gender coding of the content during the first period could be understood by the influence of physicians on the education, state governance towards education technology and harmony with the space of experience. During the whole of the studied time period, there are female coded conceptions regarding the work of the nursing teacher educators; collectivity, emphasis on practical action and control of - closeness to the student group.
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| 25. |
- Engström, Henri, et al.
(författare)
-
Mellanskarvens ekologi och effekter på fisk och fiske : Undersökning av fritidsfisket vid Gålö-Ornö, Stockholms skärgård, 1995-96 : Biologiska undersökningar vid Ringhals kraftverk 1988-1996 : Från sediment till fisk - en översiktlig studie av Vombsjönsekosystem 1994-95
- 1998
-
Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Mellanskarvens ekologi och effekter på fisk och fiskeMellanskarven är såväl en insjö- som havsfågel. Den häckar i grunda kustområden och insjöar i Syd- och Mellansverige samt sällsynt i norrlands kustland. Kärnområdet för beståndet av svenska mellanskarvar är södra Kalmarsund där skarven etablerade sig på nytt i slutet av 40-talet efter att ha varit fördriven som häckfågel i Sverige under nära 50 år. Fram till mitten på 80-talet var antalet skarvar i Sverige mycket lågt men populationen har under de därpå följande tio åren genomgått en mycket kraftig tillväxt. Denna kraftiga beståndstillväxt är gemensam för stora delar av Västeuropa, och har satts i samband med förbättrat fågelskydd samt förändringar i fiskbestånden vilken kan bero på ökad eutrofiering.Vad beträffar födan är skarven generalist och fångar de fiskarter som är vanligast förekommande och mest tillgängliga. Abborre och mört är de dominerande fiskarterna i sjöar och grunda kustområden och är också viktiga byten för skarven. I skärgårdsområden, under skarvarnas häckning, utgör även tånglake och strömming en stor andel av födan.Den urgamla konfliktsituationen mellan människa och skarv har sitt ursprung i konkurrens om en gemensam resurs samt fåglarnas påverkan på vegetationen på de öar där de häckar. Skarvens effekter på yrkesfisket kan indelas i direkta och indirekta effekter. Till direkta effekter hör skador på fisk samt förlust av fisk i redskap genom skarvpredation. Till indirekta effekter hör långsiktiga förändringar av fisksamhällena orsakat avskarvens fiskkonsumtion. Ett annat problem är att ett mycket stort antal skarvar drunknar i redskap.Bitskador på fisk av skarv i redskap förekommer lokalt i Sverige, och under vissa perioder. Av de platser där en dokumentation och kvantifiering av skador på fisk ägt rum (insjöar i Skåne och Östergötland, kustområden i norra Kalmarsund och delar av Vänern) är omfattningen av skador för närvarande förhållandevis liten. Endast i Vänern (vissa områden) och Roxen, Ög, kan stundom ett större antal fiskar vara så pass skadade att de blir osäljbara för yrkesfiskaren. Storskaliga förändringar av fiskpopulationer genom skarvpredation har i studier ej kunnat beläggas men teoretiska beräkningar av skarvarnas fiskuttag i närheten av stora kolonier antyder att fåglarna rimligen kan påverka fiskbeståndens storlek. Förändringar i fiskarnas beteende och därmed uppehållsort ärockså att vänta i närheten av stora skarvkolonier.En del yrkesfiskare uppfattar skarvens predation på ål som ett problem. Alen har ett högt kommersiellt värde och är en viktig inkomstkälla för ett antal yrkesfiskare i Syd och Mellansverige. Det är oklart hur mycket ål skarvarna konsumerar, men totalt sett är ålen av liten betydelse som föda för skarven. Ålinvandringen till svenska vatten har under senare decennier minskat utan fullgoda förklaringar. Med minskade åltätheter kan deti nte uteslutas att skarvpredation, och omfattande yrkesfiske av ål, ytterligare kan krympadet redan svaga ålbeståndet. Yrkesfisket efter ål i insjöar och i Östersjön är idag dessutom mer eller mindre helt beroende av stödutsättningar.Den kraftiga expansion av antalet skarvar som ägt rum under senare år har nu delvis avstannat. Orsaker kan vara populationsmättnad på grund av födokonkurrens, begränsande faktorer i övervintringskvarteren, brist på lämpliga boplatser samt mänsklig förföljelse vid skarvarnas häckningsplatser.
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| 26. |
- Ericsson, Stina, 1972, et al.
(författare)
-
Language that supports sustainable development: How to write about people in universal design policy
- 2020
-
Ingår i: Sustainability (Switzerland). - : MDPI AG. - 2071-1050. ; 12, s. 1-20
-
Tidskriftsartikel (refereegranskat)abstract
- Universal Design (UD) is a design approach that recognises and anticipates diversity as a fundamental human condition. UD is also frequently referred to in relation to the social dimension of sustainable development. Central to both UD and sustainability is the way “everyone,” as the target of UD and sustainability goals, is understood. The purpose of the study is to identify how UD’s “everyone” is conceptualised in Swedish UD policy and to provide a set of recommendations for how to categorise people with regards to UD. A qualitative text analysis is used, which investigates semiotic modes in relation to the content, form, and social relations of texts. Based on the analysis, two challenges for UD policy are identified: (i) how to convey that UD is design for everyone, and (ii) how to move away from a thought pattern of norm and deviation. Seven recommendations for how to approach categorisations of people in UD policy are formulated. We argue that an adoption of UD has the potential to bring about sustainable living environments for all, if integrated with social, economic, environmental, and spatial dimensions of development, but that in order for this to succeed, careful attention needs to be paid to how UD is conceptualised, and a radically different way of categorising people is necessary.
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| 27. |
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| 28. |
- Grahn, Olle; Sandström, Olof,
(författare)
-
Fallstudier vid svenska skogsindustrier som ett led i implementeringen av EG:s Ramdirektiv för vatten
- 2005
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Då implementeringen av EG:s Ramdirektiv för vatten kan få konsekvenser för den svenskaskogsindustrin miljöarbete togs kontakter med Naturvårdsverket som resulterade i ettsamfinansierat projekt. I projektet prövas grundläggande principer för direktivets tillämpningsamt möjligheten att göra statusbedömningar baserade på reviderade bedömningsgrunder(BG) för miljökvalitet tillämpade på realistiska recipientdata.Sex skogsindustrier valdes för prövningen: Karlsborgs Bruk vid Bottenviken, Vallviks brukvid Bottenhavet, Mönsterås bruk vid Egentliga Östersjön, Skoghalls Bruk vid Vänern,Billingsfors Bruk vid Laxsjön samt Klippans Pappersbruk vid Rönne å. Fabrikerna valdes så,att de skall representera olika vattenmiljöer, inte kunna klassas som kraftigt modifieradevatten samt att tillgången på recipientdata skall vara god.
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| 29. |
- Granfors, Michaela, et al.
(författare)
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Placental location and pregnancy outcomes in nulliparous women : A population-based cohort study
- 2019
-
Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : WILEY. - 0001-6349 .- 1600-0412. ; 98:8, s. 988-996
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: The impact of placenta previa on pregnancy, delivery and infant outcomes has been extensively studied. However, less is known about the possible association of placental location other than previa with pregnancy outcomes. The aim of this study was to investigate if placental location other than previa is associated with adverse pregnancy, delivery and infant outcomes.Material and methods: This is a population-based cohort study, with data from the regional population-based Stockholm-Gotland Obstetric Cohort, Sweden, from 2008 to 2014. The study population included 74 087 nulliparous women with singleton pregnancies resulting in live-born infants, with information about placental location from the second-trimester ultrasound screening. The association between placental location (fundal, lateral, anterior or posterior) and pregnancy outcomes was estimated using logistic regression analysis. Odds ratios (OR) with 95% confidence intervals (95% CI) were calculated, and adjustments were made for maternal age, height, country of birth, smoking in early pregnancy, sex of the infant and in vitro fertilization. Main outcome measures were pregnancy, delivery and infant outcomes.Results: Compared with posterior placental location, fundal and lateral placental locations were associated with a number of adverse pregnancy outcomes, the most important being: very preterm birth (<32 weeks of gestation) (adjusted OR [aOR] 1.78, 95% CI 1.18-2.63 and aOR 2.12, 95% CI 1.39-2.25, respectively), moderate preterm birth (32-36 weeks of gestation) (aOR 1.23, 95% CI 1.001-1.51 and aOR 1.62, 95% CI 1.32-2.00, respectively), small-for-gestational-age birth (aOR 1.67, 95% CI 1.34-2.07 and aOR 1.77, 95% CI 1.39-2.25, respectively) and manual removal of the placenta in vaginal births (aOR 3.27, 95% CI 2.68-3.99 and aOR 3.27, 95% CI 2.60-4.10, respectively). Additionally, lateral placental location was associated with preeclampsia (aOR 1.30, 95% CI 1.03-1.65) and severe postpartum hemorrhage (aOR 1.42, 95% CI 1.27-1.82).Conclusions: Compared with posterior placental location, fundal and lateral placental locations are associated with a number of adverse pregnancy, delivery and infant outcomes.
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| 30. |
- Granfors, Michaela, et al.
(författare)
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Placental location and risk of retained placenta in women with a previous cesarean section : A population-based cohort study.
- 2020
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - : Wiley. - 0001-6349 .- 1600-0412. ; 99:12, s. 1666-1673
-
Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: Some studies have shown that women with a previous cesarean section, compared with women with a previous vaginal delivery, have an increased risk of retained placenta during a subsequent vaginal delivery. It is unknown whether this is mediated by anterior placental location, when the placenta might cover the uterine scar. The aim of this study was to evaluate whether the increased risk of retained placenta in women with a previous cesarean section is mediated by anterior placental location.MATERIAL AND METHODS: This is a population-based cohort study, with data from the regional population-based Stockholm-Gotland Obstetric Cohort, Sweden, from 2008 to 2014. The overall study population included 49 598 women with a vaginal second delivery, where adequate information about placental location from the second-trimester ultrasound scan was available. For the main analysis, including the 3921 women with a previous cesarean section, we calculated the relative risk of retained placenta in women with an anterior placental location, using women with non-anterior placental locations as reference. Relative risks were calculated as odds ratios (OR) with 95% CI. In a second model, adjustments were made for maternal age, height, country of birth, smoking in early pregnancy, infant sex, and in vitro fertilization.RESULTS: In the overall study population, the rate of retained placenta at the second delivery was 2.0%. The proportion of women with a retained placenta was higher among women with a previous cesarean compared with those with a previous vaginal delivery (3.4% vs 1.9%; P < .0001). In the main analysis, including women with a previous cesarean section, the risk for retained placenta was not increased with anterior compared with non-anterior placental location (OR 0.84, 95% CI 0.60-1.20). Adjustments did not affect the estimates in a significant way.CONCLUSIONS: The increased risk of retained placenta in women with a previous cesarean section is not mediated by anterior placental location.
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| 31. |
- Grönberg, Per-Olof, et al.
(författare)
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Desirable skills? : Non-Nordic citizens applying for work permits in Sweden, 1947–1950
- 2015
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Ingår i: Labor history. - : Taylor & Francis. - 0023-656X .- 1469-9702. ; 56:4, s. 481-498
-
Tidskriftsartikel (refereegranskat)abstract
- Sweden's rapid economic growth after the Second World War meant that the native labour supply was incapable of meeting the high demand, especially for industrial labourers. Three agreements on organised collective transfers were signed, but a large majority of the labour migrants came on their own initiative. Not all applicants were equally welcomed. In this article, logistic regressions are used to investigate a sample of 2830 (every fifth) applications to the National Labour Market Board (AMS) from the years 1947–1950; 1367 had an arrangement with a future Swedish employer, while 1463 applicants lacked such an arrangement. The likelihood of being granted a permit was 11 times higher for the first category. Our hypothesis that the chances were better for high-skilled workers proved true only in part; it was valid if they had an employer agreement. Contrary to our assumptions, women had a better chance than men, partly because domestic servants were always permitted and partly because women did not compete with male labour. However, our assumptions with regard to better chances for the young but experienced, and for those applying for the occupation wherein they had their experience held true. A number of official documents revealed the desirability of Sudeten German labourers. They were viewed as skilled, reliable and loyal by employers, labour unions and governmental authorities. This assumption only held true for applicants lacking an employer. This can be viewed as a prolongation of the practice of helping Sudeten German Social Democrats, established in 1938. The intention to help refugees was, however, also evident in the treatment of Baltic and Polish applicants.
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| 32. |
- Hallonsten, Olof, et al.
(författare)
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Innovationism and the New Public Intellectuals
- 2024
-
Ingår i: Moonshots and the New Industrial Policy: Questioning the Mission Economy. - 2197-5884 .- 1572-1922. ; 56
-
Bokkapitel (refereegranskat)abstract
- Public intellectuals were once honest and knowledgeable academics who engaged in critical debate and spoke truth to power, but seem today rather to be celebrities who make vast amounts of money from selling an oversimplified message to policymakers and the public. This chapter discusses the role of the new public intellectuals for the rise of oversimplified and misguided innovation policy, both in the wider context of the recent spread of the ideology of “innovationism” and with specific attention to the sociological mechanisms involved. With the help of a conceptual discussion and some key examples, the chapter issues some warnings of what might happen when public intellectuals give up essential virtues of academic work in favor of fame and fortune, and the role they can then come to play in the spread of “innovationism” and misdirected innovation policy agendas.
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| 33. |
- Hedberg, Maria E., et al.
(författare)
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Prevotella jejuni sp. nov., isolated from the small intestine of a child with celiac disease.
- 2013
-
Ingår i: International journal of systematic and evolutionary microbiology. - : Microbiology Society. - 1466-5034 .- 1466-5026. ; 63:11, s. 4218-4223
-
Tidskriftsartikel (refereegranskat)abstract
- Five obligately anaerobic, Gram-negative, saccharolytic and proteolytic, non-spore-forming bacilli (CD3:27, CD3:28T, CD3:33, CD3:32 and CD3:34) are described. All five strains were isolated from the small intestine of a female child with celiac disease. The cells of the five strains were observed to be short rods or coccoid cells with longer filamentous forms seen sporadically. The organisms produced acetic acid and succinic acid as major metabolic end products. Phylogenetic analysis, based on comparative 16S rRNA gene sequence analysis revealed close relationships between CD3:27, CD3:28T and CD3:33 on one hand, between CD3:32 and P. histicola CCUG 55407T and between CD3:34 and P. melaninogenica CCUG 4944BT on the other. The strains CD3:27, CD3:28T and CD3:33 were clearly different from any other species within the genus Prevotella and most closely related to but distinct from P. melaninogenica. Based on 16S rRNA gene, RNA polymerase β-subunit gene and 60-kDa chaperonin protein subunit gene sequencing, phenotypic, chemical and biochemical properties strains CD3:27, CD3:28T and CD3:33 have been determined to represent a novel species within the genus Prevotella, named Prevotella jejuni sp. nov. Strain CD3:28T (CCUG 60371T = DSM 26989T) is the type strain of the proposed new species. All five strains were able to form homologous aggregates, in which tube-like structures were connecting individual bacteria cells. The five strains were able to bind to human intestinal carcinoma cell lines at 37 °C.
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| 34. |
- Hidemark, Ove, et al.
(författare)
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Nygotiska kyrkor i Skåne : utveckling i form, material och konstruktion 1840-1910
- 1991
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Bok (populärvet., debatt m.m.)abstract
- Denna bok har sin utgångspunkt i 1981/82 års studier i skånskt 1800-talsbyggande där Arkitekturskolans restaureringslinje valde att ägna sitt intresse åt det relativt obeaktade bestånd av nygotiska kyrkor som Skåne erbjuder. Studiernas syfte har varit attförsöka fånga kyrkornas specifika såväl estetiska som tekniska karaktäristiska och beskriva den utveckling som de representerar.
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| 35. |
- Holmgren, Kerstin, et al.
(författare)
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Harrens tillväxt i Vättern
- 2013
-
Rapport (populärvet., debatt m.m.)abstract
- Beståndet av harr i Vättern har med stor sannolikhet minskat kraftigt på senare år. Harren fångas inte upp i tillräckligt hög grad av befintliga övervakningsprogram för fisk (dels pga sitt levnadssätt, dels övervakningsprogrammens utformning)men trenden för fångst i fritidsfiske och enskilda fiskares observationer tyder på att beståndet gått tillbaka sedan slutet av 1990-talet. Det är således viktigt att förbättra kunskapen om harr i Vättern. Vi har studerat tillväxten hos harr genom att analysera de tillgängliga åldersprover från Vättern som arkiverats genom åren. Eftersom harr fångas så sällan är materialet relativt litet. De totalt 177 harrar som vi funnit i olika arkiv delades in i fem olika tidsperioder baserat på fångstdatum. Perioderna var 1935-1936; 1964-66; 1971-80; 1987-2001 och 2009-2012. Harrarna fångades främst i provfisken med översiktsnät eller i kommersiellt fiske samt i samband med sportfiske antingen i flugfiske med spö eller med flugutter. I analyserna användes endast fjäll. Först skattades fiskens slutliga fjällålder. Därefter tillbakaräknades storlek vid given ålder genom att använda sambandet mellan fjällets totalradie och fiskens totallängd vid fångsttillfället. Fjällåldern varierade mellan ett och elva år. Inga tecken på de sigmoidala tillväxtmönster som ibland finns hos fiskarter som skiftar födoslag kunde noteras. Tillväxten tycktes variera mellan de undersökta tidsperioderna. Särskilt den sista perioden (2009-2012) avvek med en väsentligt större variation i tillväxt och en lägre storlek vid åldrarna två och tre år. Harren tycktes ha snabbast tillväxt under perioden 1964-1966.
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| 36. |
- Hsiao, Ching-Lien, et al.
(författare)
-
Composition tunable Al1-xInxN nanorod arrays grown by ultra-high-vacuum magnetron sputter epitaxy
- 2011
-
Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
- Self-assembled ternary Al1-xInxN nanorod arrays with variable In concentration, 0.10 ≤ x ≤ 0.32 have been realized onto c-plane sapphire substrates by ultra-high-vacuum magnetron sputter epitaxy with Ti0.21Zr0.79N or VN seed layers assistance. The formation of nanorods was very sensitive to the applied seed layer. Without proper seed layer assistance a continuous Al1-xInxN film was grown. The nanorods exhibit hexagonal crosssections with preferential growth along the c axis. A coaxial rod structure with higher In concentration in the core was observed by (scanning) transmission electron microscopy in combination with low-loss electron energy loss spectroscopy and energy dispersive xray spectroscopy. 5 K cathodoluminescence spectroscopy of Al0.86In0.14N nanorods revealed band edge emission at ~5.46 eV, which was accompanied by a strong defectrelated emission at ~ 3.38 eV.
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| 37. |
- Hsiao, Ching-Lien, et al.
(författare)
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Spontaneous Formation of AlInN Core–Shell Nanorod Arrays by Ultrahigh-Vacuum Magnetron Sputter Epitaxy
- 2011
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Ingår i: Applied Physics Express. - : Japan Society of Applied Physics. - 1882-0786. ; 4:115002
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Tidskriftsartikel (refereegranskat)abstract
- The spontaneous formation of AlInN core–shell nanorod arrays with variable In concentration has been realized by ultrahigh-vacuum magnetron sputter epitaxy with Ti0.21Zr0.79N or VN seed layer assistance. The nanorods exhibit hexagonal cross sections with preferential growth along the c-axis. A core–shell rod structure with a higher In concentration in the core was observed by (scanning) transmission electron microscopy in combination with low-loss electron energy loss spectroscopy and energy dispersive X-ray spectroscopy. 5 K cathodoluminescence spectroscopy of Al0.86In0.14N nanorods revealed band edge emission at ∼5.46 eV, which was accompanied by a strong defect-related emission at ∼3.38 eV
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| 38. |
- Högberg, Lotta, et al.
(författare)
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Children with screening-detected coeliac disease show increased levels of nitric oxide products in urine
- 2011
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Ingår i: ACTA PAEDIATRICA. - : Blackwell Publishing Ltd. - 0803-5253 .- 1651-2227. ; 100:7, s. 1023-1027
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Tidskriftsartikel (refereegranskat)abstract
- Aim: Increased concentration of nitric oxide (NO) metabolites, nitrite and nitrate, in the urine is a strong indication of ongoing small intestinal inflammation, which is a hallmark of the enteropathy of coeliac disease (CD). It has previously been shown that children with symptomatic, untreated CD have increased levels of NO oxidation products in their urine. The aim of this study was to investigate whether screening-detected, asymptomatic coeliac children display the same urinary nitrite/nitrate pattern. Methods: In a multicenter screening study, serum samples were collected from 7208 12-year-old children without previously diagnosed CD. Sera were analysed for anti-human tissue transglutaminase (tTG) of isotype IgA. Small bowel biopsy was performed in antibody-positive children, yielding 153 new cases of CD. In the screening-detected individuals, the sum of nitrite and nitrate concentrations in the urine was analysed and used as an indicator of NO production. For comparison, 73 children with untreated, symptomatic CD were studied. Results: The nitrite/nitrate levels in children with screening-detected CD and those with untreated symptomatic CD did not differ significantly. Both groups had significantly increased urinary nitrite/nitrate concentrations compared to the children with normal small bowel biopsy (p andlt; 0.001). Conclusion: Children with screening-detected CD have increased production of NO just as children with untreated symptomatic CD. High NO metabolite levels in the urine may indicate a pathogenetic feature of CD and be a marker of major clinical importance.
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| 39. |
- Ivarsson, Anneli, et al.
(författare)
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Prevalence of Childhood Celiac Disease and Changes in Infant Feeding
- 2013
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Ingår i: Pediatrics. - : American Academy of Pediatrics. - 0031-4005 .- 1098-4275. ; 131:3, s. E687-E694
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: Between 1984 and 1996, Sweden experienced an "epidemic" of clinical celiac disease in children andlt;2 years of age, attributed partly to changes in infant feeding. Whether infant feeding affects disease occurrence and/or the clinical presentation remains unknown. We investigated and compared the total prevalence of celiac disease in 2 birth cohorts of 12-year-olds and related the findings to each cohorts ascertained infant feeding. less thanbrgreater than less thanbrgreater thanMETHODS: A 2-phase cross-sectional screening study was performed in which 13 279 children from 2 birth cohorts participated: children born during the epidemic (1993) and children born after the epidemic (1997). Previously diagnosed cases were reported and confirmed. Blood samples were analyzed for serological markers and children with positive values were referred for small intestinal biopsy. Infant feeding practices in the cohorts were ascertained via questionnaires. Prevalence comparisons were expressed as prevalence ratios. less thanbrgreater than less thanbrgreater thanRESULTS: The total prevalence of celiac disease was 29 in 1000 and 22 in 1000 for the 1993 and 1997 cohorts, respectively. Children born in 1997 had a significantly lower risk of having celiac disease compared with those born in 1993 (prevalence ratio: 0.75; 95% confidence interval: 0.60-0.93; P = .01). The cohorts differed in infant feeding (specifically, in the proportion of infants introduced to dietary gluten in small amounts during ongoing breastfeeding). less thanbrgreater than less thanbrgreater thanCONCLUSIONS: A significantly reduced prevalence of celiac disease in 12-year-olds indicates an option for disease prevention. Our findings suggest that the present infant feeding recommendation to gradually introduce gluten-containing foods from 4 months of age, preferably during ongoing breastfeeding, is favorable. Pediatrics 2013;131:e687-e694
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| 40. |
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| 41. |
- Josephson, Filip, et al.
(författare)
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Antiretroviral treatment of HIV infection: Swedish recommendations 2007.
- 2007
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Ingår i: Scandinavian journal of infectious diseases. - : Informa UK Limited. - 0036-5548 .- 1651-1980. ; 39:6-7, s. 486-507
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Tidskriftsartikel (refereegranskat)abstract
- On 3 previous occasions, in 2002, 2003 and 2005, the Swedish Medical Products Agency (Läkemedelsverket) and the Swedish Reference Group for Antiviral Therapy (RAV) have jointly published recommendations for the treatment of HIV infection. An expert group, under the guidance of RAV, has now revised the text again. Since the publication of the previous treatment recommendations, 1 new drug for the treatment of HIV has been approved - the protease inhibitor (PI) darunavir (Prezista). Furthermore, 3 new drugs have become available: the integrase inhibitor raltegravir (MK-0518), the CCR5-inhibitor maraviroc (Celsentri), both of which have novel mechanisms of action, and the non-nucleoside reverse transcriptase inhibitor (NNRTI) etravirine (TMC-125). The new guidelines differ from the previous ones in several respects. The most important of these are that abacavir is now preferred to tenofovir and zidovudine, as a first line drug in treatment-naïve patients, and that initiation of antiretroviral treatment is now recommended before the CD4 cell count falls below 250/microl, rather than 200/microl. Furthermore, recommendations on the treatment of HIV infection in children have been added to the document. As in the case of the previous publication, recommendations are evidence-graded in accordance with the Oxford Centre for Evidence Based Medicine, 2001 (see http://www.cebm.net/levels_of_evidence.asp#levels).
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| 42. |
- Koutouzi, Giasemi, 1984, et al.
(författare)
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Orthogonal Rings, Fiducial Markers, and Overlay Accuracy When Image Fusion is Used for EVAR Guidance.
- 2016
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Ingår i: European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery. - : Elsevier BV. - 1532-2165. ; 52:5, s. 604-611
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Tidskriftsartikel (refereegranskat)abstract
- Evaluation of orthogonal rings, fiducial markers, and overlay accuracy when image fusion is used for endovascular aortic repair (EVAR).This was a prospective single centre study. In 19 patients undergoing standard EVAR, 3D image fusion was used for intra-operative guidance. Renal arteries and targeted stent graft positions were marked with rings orthogonal to the respective centre lines from pre-operative computed tomography (CT). Radiopaque reference objects attached to the back of the patient were used as fiducial markers to detect patient movement intra-operatively. Automatic 3D-3D registration of the pre-operative CT with an intra-operative cone beam computed tomography (CBCT) as well as 3D-3D registration after manual alignment of nearby vertebrae were evaluated. Registration was defined as being sufficient for EVAR guidance if the deviation of the origin of the lower renal artery was less than 3mm. For final overlay registration, the renal arteries were manually aligned using aortic calcification and vessel outlines. The accuracy of the overlay before stent graft deployment was evaluated using digital subtraction angiography (DSA) as direct comparison.Fiducial markers helped in detecting misalignment caused by patient movement during the procedure. Use of automatic intensity based registration alone was insufficient for EVAR guidance. Manual registration based on vertebrae L1-L2 was sufficient in 7/19 patients (37%). Using the final adjusted registration as overlay, the median alignment error of the lower renal artery marking at pre-deployment DSA was 2mm (0-5) sideways and 2mm (0-9) longitudinally, mostly in a caudal direction.3D image fusion can facilitate intra-operative guidance during EVAR. Orthogonal rings and fiducial markers are useful for visualization and overlay correction. However, the accuracy of the overlaid 3D image is not always ideal and further technical development is needed.
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| 43. |
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| 44. |
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| 45. |
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| 46. |
- Leonhardt, Henrik, 1963, et al.
(författare)
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[Embolization of uterine arteries yields good results in symptomatic myoma] : Embolisering av uterusartärer ger god effekt vid symtomgivande myom
- 2004
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Ingår i: Läkartidningen. ; 101:13, s. 1208-14
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Tidskriftsartikel (refereegranskat)abstract
- This article summarizes the experience gained so far of uterine artery embolization (UAE) for symptomatic fibroids, reviewing publications related to this issue. More than 10 years have past since Ravina et al started to treat uterine fibroids with UAE. To date thousands of women have been embolized with excellent results and few serious complications. UAE is a successful alternative to hysterectomy for women wishing uterine preservation. Several cases of pregnancy and partus have been reported after UAE, and the method may be considered in women desiring future fertility, if the only remaining surgical option is complicated multiple myomectomy or hysterectomy. So far, recurrence after initially successful UAE has not been reported, but long-term results are yet to be determined.
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| 47. |
- Liberg, Olof, et al.
(författare)
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Så kan vargstammen räddas
- 2010
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Ingår i: Dagens nyheter. - 1101-2447.
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Tidskriftsartikel (populärvet., debatt m.m.)
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| 48. |
- Lidestav, Gun, et al.
(författare)
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Interactions between forest owners and their forests
- 2017
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Ingår i: Globalisation and change in forest ownership and forest use. - London : Palgrave Macmillan. - 9781137571151 - 9781137571168 ; , s. 97-137
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Bokkapitel (refereegranskat)abstract
- More than half of the forest land in Europe is privately owned, and ownership structure is known to have implications for management, production of timber and other forest products and services that support the transformation towards a green economy. This chapter provides examples of how we can gain knowledge about the forest and forest owner/user relationship from a structural point of view. Sweden is taken as an example because of the accessibility of continuous data on forest conditions, ownership and demographic data. It is concluded that the pace of change in ownership structure and forest management behaviour is slow. Further, neither the ongoing migration, urbanisation, ageing population nor the increased proportion of women seems to reduce the willingness to manage and harvest.
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| 49. |
- Lindhoff Larsson, Anna, et al.
(författare)
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Simultaneous or staged resection of synchronous colorectal cancer liver metastases : a 13-year institutional follow-up
- 2022
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Ingår i: HPB. - : Elsevier Science Ltd. - 1365-182X .- 1477-2574. ; 24:7, s. 1091-1099
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Tidskriftsartikel (refereegranskat)abstract
- Background: This study compared postoperative outcomes and survival rates of patients who un-derwent simultaneous or staged resection for synchronous colorectal cancer liver metastases. Methods: Between 2005 and 2018, 126 patients were registered prospectively at a university hospital in Sweden, 63 patients who underwent simultaneous resection were matched against 63 patients who underwent staged resection.Results: The length of hospital stay was shorter for the simultaneous resection group, at 11 vs 16 days, p = <0.001. Fewer patients experienced recurrence in the simultaneous resection group 39 vs 50 pa-tients, p = 0.012. There were no significant differences in disease-free survival and overall survival be-tween the groups. Age (hazard ratio [HR] 1.72; 95% CI 1.01-2.94; p = 0.049) and Clavien-Dindo score (HR 2.22; 95% CI 1.06-4.67; p = 0.035) had impact on survival. Conclusion: Colorectal cancer with synchronous liver metastases can be resected simultaneously, and enables a shorter treatment time without jeopardizing oncological outcomes.
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| 50. |
- Lindkvist, Anna, et al.
(författare)
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Attitudes on intensive forestry : an investigation into perceptions of increased production requirements in Swedish forestry
- 2012
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Ingår i: Scandinavian Journal of Forest Research. - : Taylor & Francis Group. - 0282-7581 .- 1651-1891. ; 27:5, s. 438-448
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Tidskriftsartikel (refereegranskat)abstract
- In 2008, the Swedish government launched an inquiry into the possibilities, benefits and requirements for conducting intensive forestry in part of the Swedish countryside, including fertilization, genetically improved plant material and fastgrowing species beyond what is currently allowed in Swedish legislation. Drawing upon part of that governmental investigation, this paper analyzes attitudes toward intensive forestry over time. The study draws upon studies of points of conflict written in the 1970s and 1980s, attitudes among different stakeholder groups, and interviews with forest owners and stakeholder groups potentially affected by intensive forestry. The study concludes that the diverging opinions as to what constitutes acceptable forest use have remained largely the same over the years. Radical landscape change is generally not seen as desirable, but views diverge over the use of novel tree species and the use of fertilization.
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