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Sökning: WFRF:(Santin G)

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  • Allison, J, et al. (författare)
  • Geant4 developments and applications
  • 2006
  • Ingår i: IEEE TRANSACTIONS ON NUCLEAR SCIENCE. - 0018-9499. ; 53:1, s. 270-278
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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4.
  • Reed, R. A., et al. (författare)
  • Anthology of the Development of Radiation Transport Tools as Applied to Single Event Effects
  • 2013
  • Ingår i: IEEE Transactions on Nuclear Science. - : Institute of Electrical and Electronics Engineers (IEEE). - 0018-9499 .- 1558-1578. ; 60:3, s. 1876-1911
  • Tidskriftsartikel (refereegranskat)abstract
    • This anthology contains contributions from eleven different groups, each developing and/or applying Monte Carlo-based radiation transport tools to simulate a variety of effects that result from energy transferred to a semiconductor material by a single particle event. The topics span from basic mechanisms for single-particle induced failures to applied tasks like developing websites to predict on-orbit single event failure rates using Monte Carlo radiation transport tools.
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  • Requena-Mendez, A, et al. (författare)
  • High Prevalence of Strongyloidiasis in Spain: A Hospital-Based Study
  • 2020
  • Ingår i: Pathogens (Basel, Switzerland). - : MDPI AG. - 2076-0817. ; 9:2
  • Tidskriftsartikel (refereegranskat)abstract
    • Introduction: Strongyloidiasis is a prevailing helminth infection ubiquitous in tropical and subtropical areas, however, seroprevalence data are scarce in migrant populations, particularly for those coming for Asia. Methods: This study aims at evaluating the prevalence of S. stercoralis at the hospital level in migrant populations or long term travellers being attended in out-patient and in-patient units as part of a systematic screening implemented in six Spanish hospitals. A cross-sectional study was conducted and systematic screening for S. stercoralis infection using serological tests was offered to all eligible participants. Results: The overall seroprevalence of S. stercoralis was 9.04% (95%CI 7.76–10.31). The seroprevalence of people with a risk of infection acquired in Africa and Latin America was 9.35% (95%CI 7.01–11.69), 9.22% (7.5–10.93), respectively. The number of individuals coming from Asian countries was significantly smaller and the overall prevalence in these countries was 2.9% (95%CI −0.3–6.2). The seroprevalence in units attending potentially immunosuppressed patients was significantly lower (5.64%) compared with other units of the hospital (10.20%) or Tropical diseases units (13.33%) (p < 0.001). Conclusions: We report a hospital-based strongyloidiasis seroprevalence of almost 10% in a mobile population coming from endemic areas suggesting the need of implementing strongyloidiasis screening in hospitalized patients coming from endemic areas, particularly if they are at risk of immunosuppression.
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  • Cronin, Thomas M., et al. (författare)
  • Interglacial Paleoclimate in the Arctic
  • 2019
  • Ingår i: Paleoceanography and Paleoclimatology. - 2572-4517 .- 2572-4525. ; 34:12, s. 1959-1979
  • Tidskriftsartikel (refereegranskat)abstract
    • Marine Isotope Stage 11 from similar to 424 to 374 ka experienced peak interglacial warmth and highest global sea level similar to 410-400 ka. MIS 11 has received extensive study on the causes of its long duration and warmer than Holocene climate, which is anomalous in the last half million years. However, a major geographic gap in MIS 11 proxy records exists in the Arctic Ocean where fragmentary evidence exists for a seasonally sea ice-free summers and high sea-surface temperatures (SST; similar to 8-10 degrees C near the Mendeleev Ridge). We investigated MIS 11 in the western and central Arctic Ocean using 12 piston cores and several shorter cores using proxies for surface productivity (microfossil density), bottom water temperature (magnesium/calcium ratios), the proportion of Arctic Ocean Deep Water versus Arctic Intermediate Water (key ostracode species), sea ice (epipelagic sea ice dwelling ostracode abundance), and SST (planktic foraminifers). We produced a new benthic foraminiferal delta O-18 curve, which signifies changes in global ice volume, Arctic Ocean bottom temperature, and perhaps local oceanographic changes. Results indicate that peak warmth occurred in the Amerasian Basin during the middle of MIS 11 roughly from 410 to 400 ka. SST were as high as 8-10 degrees C for peak interglacial warmth, and sea ice was absent in summers. Evidence also exists for abrupt suborbital events punctuating the MIS 12-MIS 11-MIS 10 interval. These fluctuations in productivity, bottom water temperature, and deep and intermediate water masses (Arctic Ocean Deep Water and Arctic Intermediate Water) may represent Heinrich-like events possibly involving extensive ice shelves extending off Laurentide and Fennoscandian Ice Sheets bordering the Arctic.
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  • Ersmark, T., et al. (författare)
  • Influence of geometry model approximations on Geant4 simulation results of the Columbus/ISS radiation environment
  • 2007
  • Ingår i: Radiation Measurements. - : Elsevier BV. - 1350-4487 .- 1879-0925. ; 42, s. 1342-1350
  • Tidskriftsartikel (refereegranskat)abstract
    • The influence of geometry model approximations on Geant4 Monte Carlo simulation results of the radiation environment on-board the Columbus module of the International Space Station (ISS) has been investigated. Three geometry models of Columbus with different levels of detail and a geometry model of ISS have been developed. These geometries have been used for Geant4 simulations of the radiation environment inside Columbus induced by trapped protons and Galactic Cosmic Ray protons. Simulated dose rates and particle spectra on-board Columbus for each of the three Columbus models, with or without the ISS geometry model included, are presented and compared. From comparisons of simulated dose rates and particle spectra for the three different geometry models it was found that the most detailed geometry model (750 volumes) produced results similar to a much less detailed model (23 volumes). The most detailed geometry model was concluded to be a sufficiently detailed approximation of the physical Columbus for the purpose of proton induced space radiation studies. The simulated dose rates are compatible with measurements on-board the ISS. The simulation results also show that an increase in shielding thickness decreases the simulated dose rate induced by trapped protons. For Galactic Cosmic Ray protons the dose rate remains unchanged or is slightly increased.
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11.
  • Ersmark, Tore, et al. (författare)
  • Status of the DESIRE project : Geant4 physics validation studies and first results from columbus/ISS radiation simulations
  • 2004
  • Ingår i: IEEE NUCLEAR SCIENCE SYMPOSIUM, CONFERENCE RECORD. ; , s. 1540-1544
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • The DESIRE (Dose Estimation by Simulation of the ISS Radiation Environment) project aimes to accurately calculate radiation fluxes and doses to astronauts inside the European Columbus module of the International Space Station using Geant4. Firstly physics benchmark studies have been performed and comparisons made to experimental data and other particle transport programs. This will be followed by a detailed evaluation of the incident radiation fields on the ISS and culminate with the geometry modelling and full-scale flux and dose simulations for the Columbus. Geant4 validation studies are presented here. These concern the angle and energy distribution of particles leaving irradiated targets and of energy depositions in the targets. Comparisons are made between simulations using different Geant4 physics models, experimental data and other particle transport programs. Geant4 using the "Binary Cascade" model for inelastic nucleon reactions performs very well in these comparisons but some issues with other models remain to be resolved if these models are to be used for space radiation shielding applications. Results of Geant4 simulations of the transport of relevant radiation field components through the hull of the Columbus/ISS are also presented.
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12.
  • Ersmark, Tore, et al. (författare)
  • Status of the DESIRE project : Geant4 physics validation studies and first results from columbus/ISS radiation simulations
  • 2004
  • Ingår i: IEEE Transactions on Nuclear Science. - 0018-9499 .- 1558-1578. ; 51:4, s. 1378-1384
  • Tidskriftsartikel (refereegranskat)abstract
    • The Dose Estimation by Simulation of the ISS Radiation Environment (DESIRE) project aims to accurately calculate radiation fluxes and doses to astronauts inside the European Columbus module of the International Space Station using Geant4. Since Geant4 has not been previously used for this type of application it needs to be validated. This will be followed by a detailed evaluation of the incident radiation fields on ISS and culminate with the geometry modeling and full-scale flux and dose simulations for Columbus. Geant4 validation studies and comparisons to other tools are presented. These concern the angle and energy distributions of particles leaving irradiated targets and of energy depositions in the targets. Comparisons are made between simulations using different Geant4 physics models, experimental data, and other particle transport programs. Geant4 using the Binary Cascade model for inelastic nucleon reactions performs very well in these comparisons, but some issues with other models remain to be resolved if they are to be used for space radiation shielding applications. Results of Geant4 simulations of the transport of some relevant radiation field components through the hull of a simplified model of Columbus are also presented.
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  • Luoni, F., et al. (författare)
  • Total nuclear reaction cross-section database for radiation protection in space and heavy-ion therapy applications
  • 2021
  • Ingår i: New Journal of Physics. - : IOP Publishing. - 1367-2630. ; 23:10
  • Forskningsöversikt (refereegranskat)abstract
    • Realistic nuclear reaction cross-section models are an essential ingredient of reliable heavy-ion transport codes. Such codes are used for risk evaluation of manned space exploration missions as well as for ion-beam therapy dose calculations and treatment planning. Therefore, in this study, a collection of total nuclear reaction cross-section data has been generated within a GSI-ESA-NASA collaboration. The database includes the experimentally measured total nucleus-nucleus reaction cross-sections. The Tripathi, Kox, Shen, Kox-Shen, and Hybrid-Kurotama models are systematically compared with the collected data. Details about the implementation of the models are given. Literature gaps are pointed out and considerations are made about which models fit best the existing data for the most relevant systems to radiation protection in space and heavy-ion therapy.
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15.
  • Norbury, John W., et al. (författare)
  • Are Further Cross Section Measurements Necessary for Space Radiation Protection or Ion Therapy Applications? Helium Projectiles
  • 2020
  • Ingår i: Frontiers in Physics. - : Frontiers Media SA. - 2296-424X. ; 8
  • Forskningsöversikt (refereegranskat)abstract
    • The helium ((Formula presented.) He) component of the primary particles in the galactic cosmic ray spectrum makes significant contributions to the total astronaut radiation exposure. (Formula presented.) He ions are also desirable for direct applications in ion therapy. They contribute smaller projectile fragmentation than carbon ((Formula presented.) C) ions and smaller lateral beam spreading than protons. Space radiation protection and ion therapy applications need reliable nuclear reaction models and transport codes for energetic particles in matter. Neutrons and light ions ((Formula presented.) H, (Formula presented.) H, (Formula presented.) H, (Formula presented.) He, and (Formula presented.) He) are the most important secondary particles produced in space radiation and ion therapy nuclear reactions; these particles penetrate deeply and make large contributions to dose equivalent. Since neutrons and light ions may scatter at large angles, double differential cross sections are required by transport codes that propagate radiation fields through radiation shielding and human tissue. This work will review the importance of (Formula presented.) He projectiles to space radiation and ion therapy, and outline the present status of neutron and light ion production cross section measurements and modeling, with recommendations for future needs.
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