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Sökning: WFRF:(Santis C. D. E.)

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2.
  • Elhai, M, et al. (författare)
  • Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study
  • 2019
  • Ingår i: Annals of the rheumatic diseases. - : BMJ. - 1468-2060 .- 0003-4967. ; 78:7, s. 979-987
  • Tidskriftsartikel (refereegranskat)abstract
    • To assess the safety and efficacy of rituximab in systemic sclerosis (SSc) in clinical practice.MethodsWe performed a prospective study including patients with SSc from the European Scleroderma Trials and Research (EUSTAR) network treated with rituximab and matched with untreated patients with SSc. The main outcomes measures were adverse events, skin fibrosis improvement, lung fibrosis worsening and steroids use among propensity score-matched patients treated or not with rituximab.Results254 patients were treated with rituximab, in 58% for lung and in 32% for skin involvement. After a median follow-up of 2 years, about 70% of the patients had no side effect. Comparison of treated patients with 9575 propensity-score matched patients showed that patients treated with rituximab were more likely to have skin fibrosis improvement (22.7 vs 14.03 events per 100 person-years; OR: 2.79 [1.47–5.32]; p=0.002). Treated patients did not have significantly different rates of decrease in forced vital capacity (FVC)>10% (OR: 1.03 [0.55–1.94]; p=0.93) nor in carbon monoxide diffusing capacity (DLCO) decrease. Patients having received rituximab were more prone to stop or decrease steroids (OR: 2.34 [1.56–3.53], p<0.0001). Patients treated concomitantly with mycophenolate mofetil had a trend for better outcomes as compared with patients receiving rituximab alone (delta FVC: 5.22 [0.83–9.62]; p=0.019 as compared with controls vs 3 [0.66–5.35]; p=0.012).ConclusionRituximab use was associated with a good safety profile in this large SSc-cohort. Significant change was observed on skin fibrosis, but not on lung. However, the limitation is the observational design. The potential stabilisation of lung fibrosis by rituximab has to be addressed by a randomised trial.
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3.
  • Abdellaoui, G., et al. (författare)
  • Meteor studies in the framework of the JEM-EUSO program
  • 2017
  • Ingår i: Planetary and Space Science. - : Elsevier. - 0032-0633 .- 1873-5088. ; 143, s. 245-255
  • Tidskriftsartikel (refereegranskat)abstract
    • We summarize the state of the art of a program of UV observations from space of meteor phenomena, a secondary objective of the JEM-EUSO international collaboration. Our preliminary analysis indicates that JEM-EUSO, taking advantage of its large FOV and good sensitivity, should be able to detect meteors down to absolute magnitude close to 7. This means that JEM-EUSO should be able to record a statistically significant flux of meteors, including both sporadic ones, and events produced by different meteor streams. Being unaffected by adverse weather conditions, JEM-EUSO can also be a very important facility for the detection of bright meteors and fireballs, as these events can be detected even in conditions of very high sky background. In the case of bright events, moreover, exhibiting some persistence of the meteor train, preliminary simulations show that it should be possible to exploit the motion of the ISS itself and derive at least a rough 3D reconstruction of the meteor trajectory. Moreover, the observing strategy developed to detect meteors may also be applied to the detection of nuclearites, exotic particles whose existence has been suggested by some theoretical investigations. Nuclearites are expected to move at higher velocities than meteoroids, and to exhibit a wider range of possible trajectories, including particles moving upward after crossing the Earth. Some pilot studies, including the approved Mini-EUSO mission, a precursor of JEM-EUSO, are currently operational or in preparation. We are doing simulations to assess the performance of Mini-EUSO for meteor studies, while a few meteor events have been already detected using the ground-based facility EUSO-TA.
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5.
  • Abdellaoui, G., et al. (författare)
  • First observations of speed of light tracks by a fluorescence detector looking down on the atmosphere
  • 2018
  • Ingår i: Journal of Instrumentation. - : IOP PUBLISHING LTD. - 1748-0221. ; 13
  • Tidskriftsartikel (refereegranskat)abstract
    • EUSO-Balloon is a pathfinder mission for the Extreme Universe Space Observatory onboard the Japanese Experiment Module (JEM-EUSO). It was launched on the moonless night of the 25(th) of August 2014 from Timmins, Canada. The flight ended successfully after maintaining the target altitude of 38 km for five hours. One part of the mission was a 2.5 hour underflight using a helicopter equipped with three UV light sources (LED, xenon flasher and laser) to perform an inflight calibration and examine the detectors capability to measure tracks moving at the speed of light. We describe the helicopter laser system and details of the underflight as well as how the laser tracks were recorded and found in the data. These are the first recorded laser tracks measured from a fluorescence detector looking down on the atmosphere. Finally, we present a first reconstruction of the direction of the laser tracks relative to the detector.
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6.
  • Amelino-Camelia, G., et al. (författare)
  • Physics with the KLOE-2 experiment at the upgraded DA Phi NE
  • 2010
  • Ingår i: European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 68:3-4, s. 619-681
  • Forskningsöversikt (refereegranskat)abstract
    • Investigation at a f-factory can shed light on several debated issues in particle physics. We discuss: (i) recent theoretical development and experimental progress in kaon physics relevant for the Standard Model tests in the flavor sector, (ii) the sensitivity we can reach in probing CPT and Quantum Mechanics from time evolution of entangled-kaon states, (iii) the interest for improving on the present measurements of non-leptonic and radiative decays of kaons and eta/eta' mesons, (iv) the contribution to understand the nature of light scalar mesons, and (v) the opportunity to search for narrow di-lepton resonances suggested by recent models proposing a hidden dark-matter sector. We also report on the e(+)e(-) physics in the continuum with the measurements of (multi) hadronic cross sections and the study of gamma gamma processes.
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7.
  • Mocchiutti, E., et al. (författare)
  • Cosmic–ray positron energy spectrum measured by PAMELA
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • The PAMELA satellite borne experiment is designed to study cosmic rays with great accuracy in a wide energy range. One of PAMELA’s main goal is the study of the antimatter component of cosmic rays. The experiment, housed on board the Russian satellite Resurs–DK1, was launched on June 15th 2006 and it is still taking data. In this work we present the measurement of galactic positron energy spectrum in the energy range between 500 MeV and few hundred GeV. 
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8.
  • Munini, R., et al. (författare)
  • Solar modulation of galactic cosmic rays electrons and positrons over the 23rd solar minimum with the pamela experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • The satellite-borne PAMELA experiment has been continuously collecting data since 15th June 2006, when it was launched from the Baikonur cosmodrome to detect the charged component of cosmic rays over a wide energy range and with an unprecedented statistics. The apparatus design is particularly suited for particle and antiparticle identification. The satellite quasi-polar orbit, with an inclination of 70 degrees, allows particles to be measure down to 100 MeV/n. This makes the instrument suited for the investigation of phenomena related to galactic cosmic ray solar modulation in the inner heliosphere. Data for oppositely charged particles were collected from 2006 to 2009, during the A< 0 solar minimum of solar cycle 23. The time and rigidity dependence of galactic cosmic ray electron and positron fluxes were measured. These fluxes provide important information for the study of charge dependent solar modulation effects. 
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10.
  • Carbone, R., et al. (författare)
  • Pamela observation of the 2012 may 17 gle event
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • The PAMELA (Payload for Antimatter Matter Exploration and Light-nuclei Astrophysics) satellite-borne experiment has been collecting data in orbit since July 2006, providing accurate measurements of the energy spectra and composition of the cosmic radiation from a few hundred MeV/n up to hundred GeV/n. This wide interval of measured energies makes PAMELA a unique instrument for Solar Energetic Particle (SEP) observations. Not only does it span the energy range between the ground-based neutron monitor data and the observations of SEPs from space, but also PAMELA carries out the first direct measurements of the composition for the highest energy SEP events, including those causing Ground Level Enhancements (GLEs). PAMELA has registered many SEP events in solar cycle 24 including the 2012 May 17 GLE event (GLE 71), offering unique opportunities to address the question of high-energy SEP origin. Experimental performances and preliminary results on the 2012 May 17 events will be presented. We will discuss the derived particle injection time and compare with other time scales at the Sun including the flare and CME onset times. 
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11.
  • Horwich, A, et al. (författare)
  • EAU–ESMO consensus statements on the management of advanced and variant bladder cancer - an international collaborative multi-stakeholder effort : under the auspices of the EAU and ESMO Guidelines Committees
  • 2019
  • Ingår i: Annals of Oncology. - : Oxford University Press. - 0923-7534 .- 1569-8041. ; 30:11, s. 1697-1727
  • Tidskriftsartikel (refereegranskat)abstract
    • BACKGROUND: Although guidelines exist for advanced and variant bladder cancer management, evidence is limited/conflicting in some areas and the optimal approach remains controversial.OBJECTIVE: To bring together a large multidisciplinary group of experts to develop consensus statements on controversial topics in bladder cancer management.DESIGN: A steering committee compiled proposed statements regarding advanced and variant bladder cancer management which were assessed by 113 experts in a Delphi survey. Statements not reaching consensus were reviewed; those prioritised were revised by a panel of 45 experts before voting during a consensus conference.SETTING: Online Delphi survey and consensus conference.PARTICIPANTS: The European Association of Urology (EAU), the European Society for Medical Oncology (ESMO), experts in bladder cancer management.OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Statements were ranked by experts according to their level of agreement: 1-3 (disagree), 4-6 (equivocal), 7-9 (agree). A priori (level 1) consensus was defined as ≥70% agreement and ≤15% disagreement, or vice versa. In the Delphi survey, a second analysis was restricted to stakeholder group(s) considered to have adequate expertise relating to each statement (to achieve level 2 consensus).RESULTS AND LIMITATIONS: Overall, 116 statements were included in the Delphi survey. Of these, 33 (28%) statements achieved level 1 consensus and 49 (42%) statements achieved level 1 or 2 consensus. At the consensus conference, 22 of 27 (81%) statements achieved consensus. These consensus statements provide further guidance across a broad range of topics, including the management of variant histologies, the role/limitations of prognostic biomarkers in clinical decision making, bladder preservation strategies, modern radiotherapy techniques, the management of oligometastatic disease and the evolving role of checkpoint inhibitor therapy in metastatic disease.CONCLUSIONS: These consensus statements provide further guidance on controversial topics in advanced and variant bladder cancer management until a time where further evidence is available to guide our approach.
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12.
  • Ricci, M., et al. (författare)
  • Study on 2012 march 7 solar particle event and forbush decrease with the PAMELA experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • The PAMELA (Payload for Antimatter Matter Exploration and Light-nuclei Astro-physics) space-borne experiment was launched on 15 June 2006 and has been continuously collecting data since then. The apparatus measures electrons, positrons, protons, anti-protons and heavier nuclei from about 100 MeV to several hundreds of GeV. The on-board instrumentation is built around a permanent magnet with a silicon microstrip tracker, providing charge and track detection information. During solar maximum conditions of solar cycle 24, PAMELA has been providing key information about solar energetic particles (SEPs) and their influence at Earth. We discuss here the recent 2012 March 7 SEP event with a brief comment on the subsequent Forbush decrease, registered by PAMELA. This event was also observed by Fermi/LAT exhibiting unprecedented time-extended γ-ray emission (> 100 MeV) lasting nearly 20 hours. We compare the derived accelerated ion population at the Sun with the ion population measured in space by PAMELA and discuss the implications for particle acceleration. 
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13.
  • Casolino, M., et al. (författare)
  • New upper limit on strange quark matter flux with the PAMELA experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • In this work we present a new upper limit for anomalous charge / mass (Z/A) particles with PAMELA experiment. These particles would exhibit a low velocity in the Time-of-Flight system and an high rigidity in the tracker. The redundant nature of the PAMELA detectors make it particularly suited to search for these particles in a mass number (10 ≤ A ≤ 105), charge (1≤ Z ≤ 8) and rigidity (0.4 ≤ R ≤ 1200 GV) range complementary to those of ground-based experiments. 
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14.
  • Di Felice, V., et al. (författare)
  • Solar modulation of galactic hydrogen and helium over the 23rd solar minimum with the PAMELA experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • PAMELA has been orbiting the Earth for more than six years, gathering data on solar, galactic and trapped cosmic rays during the time of the last solar minimum. The apparatus comprises a time-of-flight system, a silicon-microstrip magnetic spectrometer, a silicon-tungsten electromagnetic calorimeter, an anticoincidence system, a shower tail catcher scintillator and a neutron detector. The combination of these devices allows charged particle and antiparticle identification over a wide energy range and with an unprecedented precision. The quasi-polar orbit of the instrument, with an inclination of 70 degrees, makes it possible to measure low energy particles starting from about 100 MeV/n. In this work we present the time and rigidity dependence of the galactic proton and helium fluxes over the first 4 years of operation during the A < 0 solar minimum of solar cycle 23. 
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15.
  • Formato, V., et al. (författare)
  • Hydrogen and helium isotopes flux in cosmic rays with the PAMELA experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • PAMELA is a satellite borne experiment designed to study with great accuracy cosmic rays of galactic, solar, and trapped nature, with particular focus on the antimatter component. The detector consists of a permanent magnet spectrometer core to provide rigidity and charge sign information, a Time-of-Flight system for velocity and charge information, a Silicon-Tungsten calorimeter and a Neutron detector for lepton/hadron identification. The beta and rigidity information allow to identify isotopes for Z = 1 and Z = 2 particles in the energy range 100 MeV/n to 1 GeV/n. In this work we will present the final PAMELA results on the H and He isotope fluxes measured during the 23rd solar minimum from 2006 to 2007. Such fluxes carry relevant information helpful in constraining parameters in galactic cosmic rays propagation models complementary to those obtained from other secondary to primary measurements such as the boron-to-carbon ratio. 
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16.
  • Merge, M., et al. (författare)
  • Multi-particle analysis of the december 13th 2006 forbush decrease with PAMELA experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • In this paper we present PAMELA multi-particle observation of the Forbush decrease (FD) following the December 13th 2006 solar particle event. The FD is the sudden decrease of the galactic cosmic ray flux due to the transit of a Coronal Mass Ejection (CME). The satellite-borne experiment PAMELA on-board Resurs-DK1 satellite and consist of a magnetic spectrometer with time-of-flight and calorimeter detectors. PAMELA can study in real time with high precision the temporal and energetic evolution of several particle fluence during and after crossing of the magnetic cloud generated by the CME. The effect is stronger than what detected on ground with neutron monitor. With flux reduction can be as high as 30% decreasing at 1.5GV. No difference of the FD has been found for different particles proving that there is no charge sign dependence of FD for this event. 
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18.
  • Babusci, D., et al. (författare)
  • Precision measurement of sigma (e(+)e(-) -> pi(+)pi(-)gamma)/sigma(e(+)e(-) ->mu(+)mu(-)gamma) and determination of the pi(+)pi(-) contribution to the muon anomaly with the KLOE detector
  • 2013
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 720:4-5, s. 336-343
  • Tidskriftsartikel (refereegranskat)abstract
    • We have measured the ratio cr (e(+)e(-) -> pi(+)pi(-)gamma)/sigma(e(+)e(-) -> mu(+)mu(-)gamma), with the KLOE detector at DA Phi NE for a total integrated luminosity of similar to 240 pb(-1). From this ratio we obtain the cross section sigma (e(+)e(-) -> pi(+)pi(-)gamma). From the cross section we determine the pion form factor vertical bar F-pi vertical bar(2) and the two-pion contribution to the muon anomaly a(mu) for 0.592< M-pi pi < 0.975 GeV, Delta(pi pi) a(mu) = (385.1 +/- 1.1(stat) +/- 2.7(sys+theo)) x 10(-10). This result confirms the current discrepancy between the Standard Model calculation and the experimental measurement of the muon anomaly. (c) 2013 Elsevier B.V. All rights reserved.
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19.
  • Adriani, O., et al. (författare)
  • Antiprotons in primary cosmic radiation with PAMELA experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • The latest measurements of antiprotons spectrum and antiproton-to-proton ratio in primary cosmic rays with PAMELA experiment are presented. They are in good agreement with model of secondary production of antiprotons in Galaxy, but they do not completely rule other sources at the high-energies. 
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20.
  • Anastasi, A., et al. (författare)
  • Combination of KLOE sigma (e(+) e(-) -> pi(+)pi(-) gamma(gamma)) measurements and determination of a(mu)(pi+pi-) in the energy range 0.10 < s < 0.95 GeV2
  • 2018
  • Ingår i: Journal of High Energy Physics (JHEP). - : Springer. - 1126-6708 .- 1029-8479. ; :3
  • Tidskriftsartikel (refereegranskat)abstract
    • The three precision measurements of the cross section sigma (e(+)e(-) -> pi(+)pi(-)gamma(gamma)) using initial state radiation by the KLOE collaboration provide an important input for the prediction of the hadronic contribution to the anomalous magnetic moment of the muon. These measurements are correlated for both statistical and systematic uncertainties and, therefore, the simultaneous use of these measurements requires covariance matrices that fully describe the correlations. We present the construction of these covariance matrices and use them to determine a combined KLOE measurement for sigma (e(+)e(-) -> pi(+)pi(-)gamma(gamma)). We find, from this combination, a two-pion contribution to the muon magnetic anomaly in the energy range 0.10 < s < 0.95 GeV2 of a(mu)(pi+pi-) (489.8 +/- 1.7(stat) +/- 4.8(sys)) x 10(-10).
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21.
  • Archilli, F., et al. (författare)
  • Search for a vector gauge boson in phi meson decays with the KLOE detector KLOE-2 Collaboration
  • 2012
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 706:4-5, s. 251-255
  • Tidskriftsartikel (refereegranskat)abstract
    • The existence of a light dark force mediator has been tested with the KLOE detector at DA Phi NE. This particle, called U. is searched for using the decay chain phi -> eta U, eta -> pi(+)pi(-)pi(0), U -> e(+)e(-). No evidence is found in 1.5 fb(-1) of data. The resulting exclusion plot covers the mass range 5 < M-U < 470 MeV, setting an upper limit on the ratio between the U boson coupling constant and the One structure constant, alpha'/alpha, of <= 2 x 10(-5) at 90% C.L. for 50 < M-U < 420 MeV.
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22.
  • Babusci, D., et al. (författare)
  • A new limit on the CP violating decay K-S -> 3 pi(0) with the KLOE experiment
  • 2013
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 723:1-3, s. 54-60
  • Tidskriftsartikel (refereegranskat)abstract
    • We have carried out a new direct search for the CP violating decay K-S -> 3 pi(0) with 1.7 fb(-1) of e(+)e(-) collisions collected by the KLOE detector at the Phi-factory DA Phi NE. We have searched for this decay in a sample of about 5.9 x 10(8) KSKL events tagging the K-S by means of the K-L interaction in the calorimeter and requiring six prompt photons. With respect to our previous search, the analysis has been improved by increasing of a factor four the tagged sample and by a more effective background rejection of fake K-S tags and spurious clusters. We find no candidates in data and simulated background samples, while we expect 0.12 standard model events. Normalizing to the number of K-S -> 2 pi(0) events in the same sample, we set the upper limit on BR(K-S -> 3 pi(0)) <= 2.6 x 10(-8) at 90% C.L., five times lower than the previous limit. We also set the upper limit on the eta(000) parameter, vertical bar eta(000)vertical bar <= 0.0088 at 90% C.L., improving by a factor two the latest direct measurement. (c) 2013 Elsevier B.V. All rights reserved.
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23.
  • Babusci, D., et al. (författare)
  • Limit on the production of a light vector gauge boson in phi meson decays with the KLOE detector
  • 2013
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 720:1-3, s. 111-115
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a new limit on the production of a light dark-force mediator with the KLOE detector at DA Phi NE. This boson, called U, has been searched for in the decay phi -> eta U, U -> e(+)e(-), analyzing the. decay eta -> pi(0)pi(0)pi(0) in a data sample of 1.7 fb(-1). No structures are observed in the e(+)e(-) invariant mass distribution over the background. This search is combined with a previous result obtained from the decay eta -> pi(+)pi(-)pi(0), increasing the sensitivity. We set an upper limit at 90% C.L. on the ratio between the U boson coupling constant and the fine structure constant of alpha'/alpha < 1.7 x 10(-5) for 30 < M-U < 400 MeV and alpha'/alpha <= 8 x 10(-6) for the sub-region 50 < M-U <210 MeV. This result assumes the Vector Meson Dominance expectations for the phi eta gamma* transition form factor. The dependence of this limit on the transition form factor has also been studied.
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24.
  • Babusci, D., et al. (författare)
  • Measurement of eta meson production in gamma gamma interactions and Gamma(eta -> gamma gamma) with the KLOE detector
  • 2013
  • Ingår i: Journal of High Energy Physics (JHEP). - 1126-6708 .- 1029-8479. ; :1, s. 119-
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a measurement of eta meson production in photon-photon interactions produced by electron-positron beams colliding with root s = 1 GeV. The measurement is done with the KLOE detector at the phi-factory DA Phi NE with an integrated luminosity of 0.24 fb(-1). The e(+)e(-) -> e(+)e(-)eta cross section is measured without detecting the outgoing electron and positron, selecting the decays eta -> pi(+)pi(-)pi(0) and eta -> pi(0)pi(0)pi(0). The most relevant background is due to e(+)e(-) -> eta gamma when the monochromatic photon escapes detection. The cross section for this process is measured as sigma(e(+)e(-) -> eta gamma) = (856 +/- 8(stat) +/- 16(syst)) pb. The combined result for the e(+)e(-) -> e(+)e(-)eta cross section is sigma(e(+)e(-) -> e(+)e(-)eta) = (32.72 +/- 1.27(stat) +/- 0.70(syst)) pb. From this we derive the partial width Gamma(eta -> gamma gamma) = (520 +/- 20(stat) +/- 13(syst)) eV. This is in agreement with the world average and is the most precise measurement to date.
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25.
  • Babusci, D., et al. (författare)
  • Measurement of Γ(η→π+π-γ)/Γ(η→π+π-π0) with the KLOE detector
  • 2013
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 718:3, s. 910-914
  • Tidskriftsartikel (refereegranskat)abstract
    • The ratio Rη=Γ(η→π+π-γ)/Γ(η→π+π-π0) has been measured by analysing 22 million φ→ηγ decays collected by the KLOE experiment at DAΦNE, corresponding to an integrated luminosity of 558 pb-1. The η→π+π-γ proceeds both via the ρ resonant contribution, and possibly a non-resonant direct term, connected to the box anomaly. Our result, Rη=0.1856±0.0005stat±0.0028syst, points out a sizable contribution of the direct term to the total width. The di-pion invariant mass for the η→π+π-γ decay could be described in a model-independent approach in terms of a single free parameter, α. The determined value of the parameter α is α=(1.32±0.08stat-0.09syst+0.10±0.02theo) GeV-2.
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26.
  • Babusci, D., et al. (författare)
  • Precision tests of quantum mechanics and CPT symmetry with entangled neutral kaons at KLOE
  • 2022
  • Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479.
  • Tidskriftsartikel (refereegranskat)abstract
    • The quantum interference between the decays of entangled neutral kaons is studied in the process phi -> KSKL -> pi(+)pi(-)pi(+)pi(-), which exhibits the characteristic Einstein-Podolsky-Rosen correlations that prevent both kaons to decay into pi(+)pi(-) at the same time. This constitutes a very powerful tool for testing at the utmost precision the quantum coherence of the entangled kaon pair state, and to search for tiny decoherence and CPT violation effects, which may be justified in a quantum gravity framework. The analysed data sample was collected with the KLOE detector at DA Phi NE, the Frascati phi-factory, and corresponds to an integrated luminosity of about 1.7 fb(-1), i.e. to about 1.7 x 10(9) phi -> KSKL decays produced. From the fit of the observed Delta t distribution, being Delta t the difference of the kaon decay times, the decoherence and CPT violation parameters of various phenomenological models are measured with a largely improved accuracy with respect to previous analyses. The results are consistent with no deviation from quantum mechanics and CPT symmetry, while for some parameters the precision reaches the interesting level at which - in the most optimistic scenarios - quantum gravity effects might show up. They provide the most stringent limits up to date on the considered models.
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27.
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28.
  • Formato, V., et al. (författare)
  • Galactic boron and carbon fluxes measured by the PAMELA experiment
  • 2013
  • Ingår i: Proceedings of the 33rd International Cosmic Rays Conference, ICRC 2013. - : Sociedade Brasileira de Fisica. - 9788589064293
  • Konferensbidrag (refereegranskat)abstract
    • The PAMELA experiment is a satellite-borne apparatus that performs measurements of the cosmic radiation with a particular focus on antiparticles and light nuclei. The heart of experiment is a magnetic spectrometer to measure the particle rigidity and sign of charge. A Time-of-Flight system, a Silicon-Tungsten calorimeter, and a neutron detector allow particle identification and lepton/hadron discrimination. The apparatus is surrounded by a set of anticoincidence scintillation counters to reject multi-particle events. In this work we will present the Boron and Carbon fluxes measured by PAMELA from July 2006 to March 2008. Such data, and in particular the B/C flux ratio, can help the modelling of the galactic cosmic rays propagation. This can be a crucial point in predicting the astrophysical background of antimatter (positrons and antiprotons) in cosmic rays in the search for a dark matter signal. 
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29.
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30.
  • Anastasi, A., et al. (författare)
  • Combined limit on the production of a light gauge boson decaying into mu(+) mu(-) and pi(+) pi(-)
  • 2018
  • Ingår i: Physics Letters B. - : ELSEVIER SCIENCE BV. - 0370-2693 .- 1873-2445. ; 784, s. 336-341
  • Tidskriftsartikel (refereegranskat)abstract
    • We searched for the mu(+) mu(-) decay of a light vector gauge boson, also known as dark photon, in the e(+) e(-) -> mu(+) mu(-) gamma(ISR) process by means of the Initial State Radiation (ISR) method. We used 1.93fb(-1) of data collected by the KLOE experiment at the DA Phi NE phi-factory. No structures have been observed over the irreducible mu(+) mu(-) background. A 90% CL limit on the ratio epsilon(2)= alpha'/alpha between the dark coupling constant and the fine structure constant of 3 x 10(-6)-2 x 10(-7) has been set in the dark photon mass region between 519 MeV and 973 MeV. This new limit has been combined with the published result obtained investigating the hypothesis of the dark photon decaying into hadrons in e(+) e(-) -> pi(+) pi(-) gamma(ISR) events. The combined 90% CL limit increases the sensitivity especially in the rho-omega interference region and excludes epsilon(2) greater than (13 - 2) x 10(-7). For dark photon masses greater than 600 MeV the combined limit is lower than 8 x 10(-7) resulting more stringent than present constraints from other experiments.
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31.
  • Anastasi, A., et al. (författare)
  • Measurement of the charge asymmetry for the K-S -> pi e nu decay and test of CPT symmetry with the KLOE detector
  • 2018
  • Ingår i: Journal of High Energy Physics (JHEP). - : SPRINGER. - 1126-6708 .- 1029-8479. ; :9
  • Tidskriftsartikel (refereegranskat)abstract
    • Using 1.63 fb(-1) of integrated luminosity collected by the KLOE experiment about 7 x 10(4) K-S -> pi(+/-)e(-/+)nu decays have been reconstructed. The measured value of the charge asymmetry for this decay is A(S) = (-4.9 +/- 5.7(stat) +/- 2.6(syst)) x 10(-3) which is almost twice more precise than the previous KLOE result. The combination of these two measurements gives A(S) = (3.8 +/- 5.0(stat) +/- 2.6(syst)) x 10(-3) and, together with the asymmetry of the K-L semileptonic decay, provides significant tests of the CPT symmetry. The obtained results are in agreement with CPT invariance.
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32.
  • Babusci, D., et al. (författare)
  • Measurement of the branching fraction for the decay K-S -> pi mu nu with the KLOE detector
  • 2020
  • Ingår i: Physics Letters B. - : ELSEVIER. - 0370-2693 .- 1873-2445. ; 804
  • Tidskriftsartikel (refereegranskat)abstract
    • Based on a sample of 300 million K-S mesons produced in phi -> KLKS decays recorded by the KLOE experiment at the DA Phi NE e(+)e(-) collider we have measured the branching fraction for the decay K-S -> pi mu nu. The K-S mesons are identified by the interaction of K-L mesons in the detector. The K-S -> pi mu nu decays are selected by a boosted decision tree built with kinematic variables and by a time-of-flight measurement. Signal efficiencies are evaluated with data control samples of K-L -> pi mu nu decays. A fit to the reconstructed muon mass distribution finds 7223 +/- 180 signal events. Normalising to the K-S -> pi(+)pi(-) decay events the result for the branching fraction is B(K-S -> pi mu nu) = (4.56 +/- 0.11(stat) +/- 0.17(syst)) x 10(-4). It is the first measurement of this decay mode and the result allows an independent determination of vertical bar V-us vertical bar and a test of the lepton-flavour universality. (c) 2020 The Author. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
  •  
33.
  • Babusci, D., et al. (författare)
  • Upper limit on the eta -> pi(+)pi(-) branching fraction with the KLOE experiment
  • 2020
  • Ingår i: Journal of High Energy Physics (JHEP). - : SPRINGER. - 1126-6708 .- 1029-8479. ; :10
  • Tidskriftsartikel (refereegranskat)abstract
    • Based on an integrated luminosity of 1.61 fb(-1)e(+)e(-) collision data collected with the KLOE detector at DA Phi NE, the Frascati phi -factory, a search for the P- and CP-violating decay eta -> pi (+)pi (-) has been performed. Radiative phi -> eta gamma decay is exploited to access the eta mesons. No signal is observed in the pi (+)pi (-) invariant mass spectrum, and the upper limit on the branching fraction at 90% confidence level is determined to be B(eta -> pi (+)pi (-)) < 4.9 x 10(-6), which is approximately three times smaller than the previous KLOE result. From the combination of these two measurements we get B( -> pi (+)pi (-)) < 4.4 x 10(-6) at 90% confidence level.
  •  
34.
  • Babusci, D., et al. (författare)
  • Test of CPT and Lorentz symmetry in entangled neutral kaons with the KLOE experiment
  • 2014
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 730, s. 89-94
  • Tidskriftsartikel (refereegranskat)abstract
    • Neutral kaon pairs produced in phi decays in anti-symmetric entangled state can be exploited to search for violation of CPT symmetry and Lorentz invariance. We present an analysis of the CP-violating process phi -> KSKL -> pi(+)pi(-)pi(+)pi(-) based on 1.7 fb(-1) of data collected by the KLOE experiment at the Frascati phi-factory DA Phi NE. The data are used to perform a Measurement of the CPT-violating parameters Delta a(mu) for neutral kaons in the context of the Standard Model Extension framework. The parameters measured in the reference frame of the fixed stars are: Delta a(0) = (-6.0 +/- 7.7(stat)+/- 3.1(syst)) X 10(-18) GeV, Delta a(x) = (0.9 +/- 1.5(stat)+/- 0.6(syst)) X 10(-18) GeV, Delta a(y) = (-2.0 +/- 1.5(stat)+/- 0.5(syst)) X 10(-18) GeV, Delta a(z) = (3.1 +/- 1.7(stat)+/- 0.5(syst)) X 10(-18) GeV. These are presently the most precise measurements in the quark sector of the Standard Model Extension. (C) 2014 The Authors. Published by Elsevier B.V.
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35.
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36.
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37.
  • Anastasi, A., et al. (författare)
  • Limit on the production of a low-mass vector boson in e(+)e(-) -> U gamma, U -> e(+)e(-) with the KLOE experiment
  • 2015
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 750, s. 633-637
  • Tidskriftsartikel (refereegranskat)abstract
    • The existence of a new force beyond the Standard Model is compelling because it could explain several striking astrophysical observations which fail standard interpretations. We searched for the light vector mediator of this dark force, the U boson, with the KLOE detector at the DA Phi NE e(+)e(-) collider. Using an integrated luminosity of 1.54 fb(-1), we studied the process e(+)e(-) -> U gamma, with U -> e(+)e(-), using radiative return to search for a resonant peak in the dielectron invariant-mass distribution. We did not find evidence for a signal, and set a 90% CL upper limit on the mixing strength between the Standard Model photon and the dark photon, epsilon(2), at 10(-6)-10(-4) in the 5-520 MeV/c(2) mass range.
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38.
  • Anastasi, A., et al. (författare)
  • Limit on the production of a new vector boson in e+e− → Uγ, U → π+π− with the KLOE experiment
  • 2016
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 757, s. 356-361
  • Tidskriftsartikel (refereegranskat)abstract
    • Abstract The recent interest in a light gauge boson in the framework of an extra U(1) symmetry motivates searches in the mass range below 1 GeV. We present a search for such a particle, the dark photon, in e + e − → U γ , U → π + π − based on 28 million e + e − → π + π − γ events collected at DAΦNE by the KLOE experiment. The π + π − production by initial-state radiation compensates for a loss of sensitivity of previous KLOE U → e + e − , μ + μ − searches due to the small branching ratios in the ρ – ω resonance region. We found no evidence for a signal and set a limit at 90% CL on the mixing strength between the photon and the dark photon, ε 2 , in the U mass range between 527 and 987 MeV . Above 700 MeV this new limit is more stringent than previous ones.
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39.
  • Anastasi, A., et al. (författare)
  • Measurement of the running of the fine structure constant below 1 GeV with the KLOE detector
  • 2017
  • Ingår i: Physics Letters B. - : ELSEVIER SCIENCE BV. - 0370-2693 .- 1873-2445. ; 767, s. 485-492
  • Tidskriftsartikel (refereegranskat)abstract
    • We have measured the running of the effective QED coupling constant alpha(s) in the time-like region 0.6 < root s < 0.975 GeV with the KLOE detector at DA Phi NE using the Initial-State Radiation process e(+) e(-) -> mu(+) mu(-)gamma. It represents the first measurement of the running of alpha(s) in this energy region. Our results show a more than 5 sigma significance of the hadronic contribution to the running of alpha(s), which is the strongest direct evidence both in time- and space-like regions achieved in a single measurement. By using the e(+) e(-) -> pi(+) pi(-) cross section measured by KLOE, the real and imaginary parts of the shift Delta alpha(s) have been extracted. From a fit of the real part of Delta alpha(s) and assuming the lepton universality the branching ratio BR(omega -> mu(+) mu(-)) = (6.6 +/- 1.4(stat) +/- 1.7(syst)) (.) 10 (5)has been determined.
  •  
40.
  • Anastasi, A., et al. (författare)
  • Precision measurement of the η → π + π − π 0 Dalitz plot distribution with the KLOE detector
  • 2016
  • Ingår i: Journal of High Energy Physics (JHEP). - 1126-6708 .- 1029-8479. ; :5
  • Tidskriftsartikel (refereegranskat)abstract
    • Using 1.6 fb−1 of e + e − → ϕ → ηγ data collected with the KLOE detector at DAΦNE, the Dalitz plot distribution for the η → π + π − π 0 decay is studied with the world’s largest sample of ∼ 4.7 · 106 events. The Dalitz plot density is parametrized as a polynomial expansion up to cubic terms in the normalized dimensionless variables X and Y . The experiment is sensitive to all charge conjugation conserving terms of the expansion, including a gX 2 Y term. The statistical uncertainty of all parameters is improved by a factor two with respect to earlier measurements.
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41.
  • Anastasi, A., et al. (författare)
  • Search for dark Higgsstrahlung in e(+0)e(-) -> mu(+)mu(-) and missing energy events with the KLOE experiment
  • 2015
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 747, s. 365-372
  • Tidskriftsartikel (refereegranskat)abstract
    • We searched for evidence of a Higgsstrahlung process in a secluded sector, leading to a final state with a dark photon U and a dark Higgs boson h', with the KLOE detector at DA Phi NE. We investigated the case of h' lighter than U, with U decaying into a muon pair and h' producing a missing energy signature. We found no evidence of the process and set upper limits to its parameters in the range 2m(mu) < m(U) < 1000 MeV, m(h') < m(U). (C) 2015 The Authors. Published by Elsevier B.V.
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42.
  • Babusci, D., et al. (författare)
  • Direct tests of T, CP, CPT symmetries in transitions of neutral K mesons with the KLOE experiment
  • 2023
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 845
  • Tidskriftsartikel (refereegranskat)abstract
    • Tests of the T, CP and CPT symmetries in the neutral kaon system are performed by the direct comparison of the probabilities of a kaon transition process to its symmetry-conjugate. The exchange of in and out states required for a genuine test involving an antiunitary transformation implied by time-reversal is implemented exploiting the entanglement of K0K0 pairs produced at a 0 -factory.A data sample collected by the KLOE experiment at DAONE corresponding to an integrated luminosity of about 1.7 fb-1 is analysed to study the At distributions of the 0 -> KSKL -> pi+pi- pi +/- e -/+ v and 0 -> KSKL -> pi +/- e -/+ v3 pi 0 processes, with At the difference of the kaon decay times. A comparison of the measured At distributions in the asymptotic region At â … iS allows to test for the first time T and CPT symmetries in kaon transitions with a precision of few percent, and to observe CP violation with this novel method.
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43.
  • Babusci, D., et al. (författare)
  • Measurement of the K-S ? : pe? branching fraction with the KLOE experiment
  • 2023
  • Ingår i: Journal of High Energy Physics (JHEP). - : Springer Nature. - 1126-6708 .- 1029-8479. ; :2
  • Tidskriftsartikel (refereegranskat)abstract
    • The ratio R = gamma(K-S -> pi e nu)/gamma(KS -> pi(+)pi(-)) has been measured with a sample of 300 million KS mesons produced in phi -KLKS decays recorded by the KLOE experiment at the DA Phi NE e(+)e(-) collider. K-S -> pi e nu events are selected by a boosted decision tree built with kinematic variables and time-of-flight measurements. Data control samples of K-L -> pi e nu decays are used to evaluate signal selection efficiencies. With 49647 +/- 316 signal events we measure R = (1.0421 +/- 0.0066(stat) +/- 0.0075(syst)) x 10(-3). The combination with our previous measurement gives R = (1.0338 +/- 0.0054(stat) +/- 0.0064(syst)) x 10(-3). From this value we derive the branching fraction B(K-S -> pi e nu) = (7.153 +/- 0.037(stat)+/- 0.044(syst)) x 10(-4) and f(+)(0)|V-us| = 0.2170 +/- 0.009.
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44.
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45.
  • Munini, R., et al. (författare)
  • Evidence of Energy and Charge Sign Dependence of the Recovery Time for the 2006 December Forbush Event Measured by the PAMELA Experiment
  • 2018
  • Ingår i: Astrophysical Journal. - : Institute of Physics Publishing (IOPP). - 0004-637X .- 1538-4357. ; 853:1
  • Tidskriftsartikel (refereegranskat)abstract
    • New results on the short-term galactic cosmic-ray (GCR) intensity variation (Forbish decrease) in 2006 December measured by the PAMELA instrument are presented. Forbush decreases are sudden suppressions of the GCR intensities, which are associated with the passage of interplanetary transients such as shocks and interplanetary coronal mass ejections (ICMEs). Most of the past measurements of this phenomenon were carried out with groundbased detectors such as neutron monitors or muon telescopes. These techniques allow only the indirect detection of the overall GCR intensity over an integrated energy range. For the first time, thanks to the unique features of the PAMELA magnetic spectrometer, the Forbush decrease, commencing on 2006 December 14 and following a CME at the Sun on 2006 December 13, was studied in a wide rigidity range (0.4-20 GV) and for different species of GCRs detected directly in space. The daily averaged GCR proton intensity was used to investigate the rigidity dependence of the amplitude and the recovery time of the Forbush decrease. Additionally, for the first time, the temporal variations in the helium and electron intensities during a Forbush decrease were studied. Interestingly, the temporal evolutions of the helium and proton intensities during the Forbush decrease were found to be in good agreement, while the low rigidity electrons (<2 GV) displayed a faster recovery. This difference in the electron recovery is interpreted as a charge sign dependence introduced by drift motions experienced by the GCRs during their propagation through the heliosphere.
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46.
  • Adriani, O., et al. (författare)
  • Cosmic-Ray Positron Energy Spectrum Measured by PAMELA
  • 2013
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 111:8, s. 081102-
  • Tidskriftsartikel (refereegranskat)abstract
    • Precision measurements of the positron component in the cosmic radiation provide important information about the propagation of cosmic rays and the nature of particle sources in our Galaxy. The satellite-borne experiment PAMELA has been used to make a new measurement of the cosmic-ray positron flux and fraction that extends previously published measurements up to 300 GeV in kinetic energy. The combined measurements of the cosmic-ray positron energy spectrum and fraction provide a unique tool to constrain interpretation models. During the recent solar minimum activity period from July 2006 to December 2009, approximately 24 500 positrons were observed. The results cannot be easily reconciled with purely secondary production, and additional sources of either astrophysical or exotic origin may be required.
  •  
47.
  • Adriani, O., et al. (författare)
  • Time Dependence Of The Proton Flux Measured By Pamela During The 2006 July-2009 December Solar Minimum
  • 2013
  • Ingår i: Astrophysical Journal. - : IOP Publishing. - 0004-637X .- 1538-4357. ; 765:2, s. 91-
  • Tidskriftsartikel (refereegranskat)abstract
    • The energy spectra of galactic cosmic rays carry fundamental information regarding their origin and propagation. These spectra, when measured near Earth, are significantly affected by the solar magnetic field. A comprehensive description of the cosmic radiation must therefore include the transport and modulation of cosmic rays inside the heliosphere. During the end of the last decade, the Sun underwent a peculiarly long quiet phase well suited to study modulation processes. In this paper we present proton spectra measured from 2006 July to 2009 December by PAMELA. The large collected statistics of protons allowed the time variation to be followed on a nearly monthly basis down to 400 MV. Data are compared with a state-of-the-art three-dimensional model of solar modulation.
  •  
48.
  • Babusci, D., et al. (författare)
  • Search for light vector boson production in e(+)e(-) -> mu(+)mu(-)gamma interactions with the KLOE experiment
  • 2014
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 736, s. 459-464
  • Tidskriftsartikel (refereegranskat)abstract
    • We have searched for a light vector boson U, the possible carrier of a "dark force", with the KLOE detector at the DA Phi NE e(+)e(-) collider, motivated by astrophysical evidence for the presence of dark matter in the Universe. Using e(+)e(-) collisions collected with an integrated luminosity of 239.3 pb(-1), we look for a dimuon mass peak in the reaction e(+)e(-) -> mu(+)mu(-)gamma, corresponding to the decay U -> mu(+)mu(-). We find no evidence for a U vector boson signal. We set a 90% CL upper limit for the mixing parameter squared between the photon and the U boson of 1.6 x 10(-5) to 8.6 x 10(-7) for the mass region 520 < m(U) < 980 MeV.  
  •  
49.
  • Babusci, D., et al. (författare)
  • Study of the Dalitz decay phi -> eta e(+)e(-) with the KLOE detector
  • 2015
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 742, s. 1-6
  • Tidskriftsartikel (refereegranskat)abstract
    • We have studied the vector to pseudoscalar conversion decay phi -> eta e(+)e(-), with.. eta -> pi(0)pi(0)pi(0), with the KLOE detector at DA phi NE. The data set of 1.7 fb(-1) of e(+)e(-) collisions at root s similar to M-phi contains a clear conversion decay signal of similar to 31,000 events from which we measured a value of BR(phi -> eta e(+)e-) = (1.075 +/- 0.007 +/- 0.038) x 10(-4). The same sample is used to determine the transition form factor by a fit to the e(+)e(-) invariant mass spectrum, obtaining b(phi eta)=( 1.28 +/- 0.10(-0.08)(+0.09)) GeV-2, that improves by a factor of five the precision of the previous measurement and is in good agreement with VMD expectations.
  •  
50.
  • Babuscih, D., et al. (författare)
  • Measurement of the absolute branching ratio of the K+ -> pi(+) pi(-) pi(+) (gamma) decay with the KLOE detector
  • 2014
  • Ingår i: Physics Letters B. - : Elsevier BV. - 0370-2693 .- 1873-2445. ; 738, s. 128-133
  • Tidskriftsartikel (refereegranskat)abstract
    • The absolute branching ratio of the K+ -> pi(+) pi(-) pi(+) (gamma) decay, inclusive of final-state radiation, has been measured using similar to 17 million tagged K+ mesons collected with the KLOE detector at DA Phi NE, the Frascati phi-factory. The result is: BR(K+ -> pi(+) pi(-) pi(+) (gamma)) = 0.05565 +/- 0.00031(stat) +/- 0.00025(syst) a factor similar or equal to 5 more precise with respect to the previous result. This work completes the program of precision measurements of the dominant kaon branching ratios at KLOE.
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