| 1. |
- Ceberg, Sofie, et al.
(författare)
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Tumor-tracking radiotherapy of moving targets; verification using 3D polymer gel, 2D ion-chamber array and biplanar diode array
- 2010
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Ingår i: Journal of Physics: Conference Series. - : IOP Publishing. - 1742-6588 .- 1742-6596. ; 250:1, s. 235-239
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Tidskriftsartikel (refereegranskat)abstract
- The aim of this study was to carry out a dosimetric verification of a dynamic multileaf collimator (DMLC)-based tumor-tracking delivery during respiratory-like motion. The advantage of tumor-tracking radiation delivery is the ability to allow a tighter margin around the target by continuously following and adapting the dose delivery to its motion. However, there are geometric and dosimetric uncertainties associated with beam delivery system constraints and output variations, and several investigations have to be accomplished before a clinical integration of this tracking technique. Two types of delivery were investigated in this study I) a single beam perpendicular to a target with a one dimensional motion parallel to the MLC moving direction, and II) an intensity modulated arc delivery (RapidArc®) with a target motion diagonal to the MLC moving direction. The feasibility study (I) was made using an 2D ionisation chamber array and a true 3D polymer gel. The arc delivery (II) was verified using polymer gel and a biplanar diode array. Good agreement in absorbed dose was found between delivery to a static target and to a moving target with DMLC tracking using all three detector systems. However, due to the limited spatial resolution of the 2D array a detailed comparison was not possible. The RapidArc® plan delivery was successfully verified using the biplanar diode array and true 3D polymer gel, and both detector systems could verify that the DMLC-based tumor-tracking delivery system has a very good ability to account for respiratory target motion.
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| 2. |
- Oey, M. S., et al.
(författare)
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Nebular C iv λ1550 Imaging of the Metal-poor Starburst Mrk 71 : Direct Evidence of Catastrophic Cooling
- 2023
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Ingår i: Astrophysical Journal Letters. - 2041-8205 .- 2041-8213. ; 958:1
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Tidskriftsartikel (refereegranskat)abstract
- We use the Hubble Space Telescope Advanced Camera for Surveys to obtain the first spatially resolved, nebular imaging in the light of C ivλλ1548, 1551 by using the F150LP and F165LP filters. These observations of the local starburst Mrk 71 in NGC 2366 show emission apparently originating within the interior cavity around the dominant super star cluster (SSC), Knot A. Together with imaging in He iiλ4686 and supporting Space Telescope Imaging Spectrograph far-ultraviolet spectroscopy, the morphology and intensity of the C iv nebular surface brightness and the C iv/He ii ratio map provide direct evidence that the mechanical feedback is likely dominated by catastrophic radiative cooling, which strongly disrupts adiabatic superbubble evolution. The implied extreme mass loading and low kinetic efficiency of the cluster wind are reasonably consistent with the wind energy budget, which is probably enhanced by radiation pressure. In contrast, the Knot B SSC lies within a well-defined superbubble with associated soft X-rays and He iiλ1640 emission, which are signatures of adiabatic, energy-driven feedback from a supernova-driven outflow. This system lacks clear evidence of C iv from the limb-brightened shell, as expected for this model, but the observations may not be deep enough to confirm its presence. We also detect a small C iv-emitting object that is likely an embedded compact H ii region. Its C iv emission may indicate the presence of very massive stars (>100 M⊙) or strongly pressure-confined stellar feedback.
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