| 1. |
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| 2. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 3. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 4. |
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| 5. |
- Glasbey, JC, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 6. |
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| 7. |
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| 8. |
- Kattge, Jens, et al.
(författare)
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TRY plant trait database - enhanced coverage and open access
- 2020
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Ingår i: Global Change Biology. - : Wiley-Blackwell. - 1354-1013 .- 1365-2486. ; 26:1, s. 119-188
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Tidskriftsartikel (refereegranskat)abstract
- Plant traits-the morphological, anatomical, physiological, biochemical and phenological characteristics of plants-determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits-almost complete coverage for 'plant growth form'. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait-environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.
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| 9. |
- Burdett, S., et al.
(författare)
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Adjuvant chemotherapy for resected early-stage non-small cell lung cancer
- 2015
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Ingår i: Cochrane Database of Systematic Reviews. - 1469-493X. ; :3
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Forskningsöversikt (refereegranskat)abstract
- Background To evaluate the effects of administering chemotherapy following surgery, or following surgery plus radiotherapy (known as adjuvant chemotherapy) in patients with early stage non-small cell lung cancer (NSCLC), we performed two systematic reviews andmeta-analyses of all randomised controlled trials using individual participant data. Results were first published in The Lancet in 2010. Objectives To compare, in terms of overall survival, time to locoregional recurrence, time to distant recurrence and recurrence-free survival: A. Surgery versus surgery plus adjuvant chemotherapy B. Surgery plus radiotherapy versus surgery plus radiotherapy plus adjuvant chemotherapy in patients with histologically diagnosed early stage NSCLC. (2) To investigate whether or not predefined patient subgroups benefit more or less from cisplatin-based chemotherapy in terms of survival. Search methods We supplemented MEDLINE and CANCERLIT searches (1995 to December 2013) with information from trial registers, hand-searching relevant meeting proceedings and by discussion with trialists and organisations. Selection criteria We included trials of a) surgery versus surgery plus adjuvant chemotherapy; and b) surgery plus radiotherapy versus surgery plus radiotherapy plus adjuvant chemotherapy, provided that they randomised NSCLC patients using a method which precluded prior knowledge of treatment assignment. Data collection and analysis We carried out a quantitative meta-analysis using updated information from individual participants from all randomised trials. Data from all patients were sought from those responsible for the trial. We obtained updated individual participant data (IPD) on survival, and date of last follow-up, as well as details of treatment allocated, date of randomisation, age, sex, histological cell type, stage, and performance status. To avoid potential bias, we requested information for all randomised patients, including those excluded from the investigators' original analyses. We conducted all analyses on intention-to-treat on the endpoint of survival. For trials using cisplatin-based regimens, we carried out subgroup analyses by age, sex, histological cell type, tumour stage, and performance status. Main results We identified 35 trials evaluating surgery plus adjuvant chemotherapy versus surgery alone. IPD were available for 26 of these trials and our analyses are based on 8447 participants (3323 deaths) in 34 trial comparisons. There was clear evidence of a benefit of adding chemotherapy after surgery (hazard ratio (HR)= 0.86, 95% confidence interval (CI)= 0.81 to 0.92, p< 0.0001), with an absolute increase in survival of 4% at five years. We identified 15 trials evaluating surgery plus radiotherapy plus chemotherapy versus surgery plus radiotherapy alone. IPD were available for 12 of these trials and our analyses are based on 2660 participants (1909 deaths) in 13 trial comparisons. There was also evidence of a benefit of adding chemotherapy to surgery plus radiotherapy (HR= 0.88, 95% CI= 0.81 to 0.97, p= 0.009). This represents an absolute improvement in survival of 4% at five years. For both meta-analyses, we found similar benefits for recurrence outcomes and there was little variation in effect according to the type of chemotherapy, other trial characteristics or patient subgroup. We did not undertake analysis of the effects of adjuvant chemotherapy on quality of life and adverse events. Quality of life information was not routinely collected during the trials, but where toxicity was assessed and mentioned in the publications, it was thought to be manageable. We considered the risk of bias in the included trials to be low. Authors' conclusions Results from 47 trial comparisons and 11,107 patients demonstrate the clear benefit of adjuvant chemotherapy for these patients, irrespective of whether chemotherapy was given in addition to surgery or surgery plus radiotherapy. This is the most up-to-date and complete systematic review and individual participant data (IPD) meta-analysis that has been carried out.
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| 10. |
- Garibaldi, Lucas A., et al.
(författare)
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Wild Pollinators Enhance Fruit Set of Crops Regardless of Honey Bee Abundance
- 2013
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Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 339:6127, s. 1608-1611
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Tidskriftsartikel (refereegranskat)abstract
- The diversity and abundance of wild insect pollinators have declined in many agricultural landscapes. Whether such declines reduce crop yields, or are mitigated by managed pollinators such as honey bees, is unclear. We found universally positive associations of fruit set with flower visitation by wild insects in 41 crop systems worldwide. In contrast, fruit set increased significantly with flower visitation by honey bees in only 14% of the systems surveyed. Overall, wild insects pollinated crops more effectively; an increase in wild insect visitation enhanced fruit set by twice as much as an equivalent increase in honey bee visitation. Visitation by wild insects and honey bees promoted fruit set independently, so pollination by managed honey bees supplemented, rather than substituted for, pollination by wild insects. Our results suggest that new practices for integrated management of both honey bees and diverse wild insect assemblages will enhance global crop yields.
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| 11. |
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| 12. |
- Alwall, J., et al.
(författare)
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A standard format for Les Houches Event Files
- 2007
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Ingår i: Computer Physics Communications. - : Elsevier BV. - 0010-4655. ; 176:4, s. 300-304
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Tidskriftsartikel (refereegranskat)abstract
- A standard file format is proposed to store process and event information, primarily output from partoti-level event generators for further use by general-purpose ones. The information content is identical with what was already defined by the Les Houches Accord five years ago, but then in terms of Fortran commonblocks. This information is embedded in a minimal XML-style structure, for clarity and to simplify parsing.
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| 13. |
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| 14. |
- Emonts, B., et al.
(författare)
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A CO-rich merger shaping a powerful and hyperluminous infrared radio galaxy at z=2: the Dragonfly Galaxy
- 2015
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 451:1, s. 1025-1035
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Tidskriftsartikel (refereegranskat)abstract
- In the low-redshift Universe, the most powerful radio sources are often associated with gasrich galaxy mergers or interactions. We here present evidence for an advanced, gas-rich ('wet') merger associated with a powerful radio galaxy at a redshift of z similar to 2. This radio galaxy, MRC 0152-209, is the most infrared-luminous high-redshift radio galaxy known in the Southern hemisphere. Using the Australia Telescope Compact Array, we obtained highresolution CO(1-0) data of cold molecular gas, which we complement with Hubble Space Telescope (HS7)IWide Field Planetaiy Camera 2 (WFPC2) imaging and William Herschel Telescope long-slit spectroscopy. We find that, while roughly M-H2 x 10(10) Me of molecular gas coincides with the central host galaxy, another M-H2 similar to 3 x 10(10) Me is spread across a total extent of'-60 kpc. Most of this widespread CO(1-0) appears to follow prominent tidal features visible in the rest-frame near-UV HSTIWFPC2 imaging. Lya emission shows an excess over He II, but a deficiency over LIR, which is likely the result of photoionization by enhanced but very obscured star formation that was triggered by the merger. In terms of feedback, the radio source is aligned with widespread CO(1-0) emission, which suggests that there is a physical link between the propagating radio jets and the presence of cold molecular gas on scales of the galaxy's halo. Its optical appearance, combined with the transformational stage at which we witness the evolution of MRC 0152-209, leads us to adopt the name 'Dragonfly Galaxy'.
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| 15. |
- Andersson, Bo, et al.
(författare)
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Small x phenomenology: summary and status
- 2002
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Ingår i: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 25:1, s. 77-101
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Forskningsöversikt (refereegranskat)abstract
- The aim of this paper is to summarize the general status of our understanding of small-x physics. It is based on presentations and discussions at an informal meeting OIL this topic held in Lund, Sweden, in March 2001. This document also marks the founding of an informal collaboration between experimentalists and theoreticians with a special interest in small-x physics. This paper is dedicated to the memory of Bo Andersson. who died unexpectedly from a heart attack on March 4th, 2002.
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| 16. |
- Buttar, C.M., et al.
(författare)
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The Underlying Event
- 2005
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Ingår i: HERA and the LHC: A Workshop on the implications of HERA for LHC physics.
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)
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| 17. |
- Huynh, M. T., et al.
(författare)
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Physical conditions of the gas in an ALMA C II -identified submillimetre galaxy at z=4.44
- 2013
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966 .- 1745-3933 .- 1745-3925. ; 431:1, s. L88-L92
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Tidskriftsartikel (refereegranskat)abstract
- We present (CO)-C-12(2-1) observations of the submillimetre galaxy ALESS65.1 performed with the Australia Telescope Compact Array (ATCA) at 42.3 GHz. A previous Atacama Large Millimeter Array study of submillimetre galaxies (SMGs) in the Extended Chandra Deep Field South detected [C II] 157.74 mu m emission from this galaxy at a redshift of z= 4.44. No (CO)-C-12(21) emission was detected but we derive a firm upper limit to the cold gas mass in ALESS65.1 of M-gas 4 SMGs being the likely progenitors of massive red-and-dead galaxies at z > 2. The ratio of the [CII], (CO)-C-12 and far-infrared luminosities implies a strong far-ultraviolet field of G(0) greater than or similar to 103, as seen in Galactic star-forming regions or local ultraluminous infrared galaxies (ULIRGs). The observed L-[C II]/L-FIR = 2.3 x 10(-3) is high compared to local ULIRGs and, combined withLL([CII])/L-CO greater than or similar to 2700, it is consistent with ALESS65.1 either having an extended (several kpc) [C II] emitting region or lower than solar metallicity.
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| 18. |
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| 19. |
- Papamichael, D., et al.
(författare)
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Treatment of colorectal cancer in older patients : International Society of Geriatric Oncology (SIOG) consensus recommendations 2013
- 2015
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Ingår i: Annals of Oncology. - : Elsevier BV. - 0923-7534 .- 1569-8041. ; 26:3, s. 463-476
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Forskningsöversikt (refereegranskat)abstract
- Colorectal cancer (CRC) is one of the most commonly diagnosed cancers in Europe and worldwide, with the peak incidence in patients >70 years of age. However, as the treatment algorithms for the treatment of patients with CRC become ever more complex, it is clear that a significant percentage of older CRC patients (>70 years) are being less than optimally treated. This document provides a summary of an International Society of Geriatric Oncology (SIOG) task force meeting convened in Paris in 2013 to update the existing expert recommendations for the treatment of older (geriatric) CRC patients published in 2009 and includes overviews of the recent data on epidemiology, geriatric assessment as it relates to surgery and oncology, and the ability of older CRC patients to tolerate surgery, adjuvant chemotherapy, treatment of their metastatic disease including palliative chemotherapy with and without the use of the biologics, and finally the use of adjuvant and palliative radiotherapy in the treatment of older rectal cancer patients. An overview of each area was presented by one of the task force experts and comments invited from other task force members.
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| 20. |
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| 21. |
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| 22. |
- Drouart, Guillaume, 1987, et al.
(författare)
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Rapidly growing black holes and host galaxies in the distant Universe from the Herschel Radio Galaxy Evolution Project
- 2014
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 566
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Tidskriftsartikel (refereegranskat)abstract
- We present results from a comprehensive survey of 70 radio galaxies at redshifts 1 10(12) L-circle dot) or hyper-luminous (L-tot(IR) > 10(13) L-circle dot) infrared galaxies. We fit the infrared SEDs with a set of empirical templates which represent dust heated by a variety of starbursts (SB) and by an active galactic nucleus (AGN). We find that the SEDs of radio galaxies require the dust to be heated by both AGN and SB, but the luminosities of these two components are not strongly correlated. Assuming empirical relations and simple physical assumptions, we calculate the star formation rate (SFR), the black hole mass accretion rate ((M) over dot(BH)), and the black hole mass (M-BH) for each radio galaxy. We find that the host galaxies and their black holes are growing extremely rapidly, having SFR approximate to 100-5000 M-circle dot yr(-1) and. (M) over dot(BH) approximate to 1-100 M(circle dot)yr(-1). The mean specific SFRs (sSFR) of radio galaxies at z > 2 : 5 are higher than the sSFR of typical star forming galaxies over the same redshift range, but are similar or perhaps lower than the galaxy population for radio galaxies at z
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| 23. |
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| 24. |
- Morschhauser, F., et al.
(författare)
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Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma
- 2010
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Ingår i: Annals of Oncology. - : Elsevier BV. - 1569-8041 .- 0923-7534. ; 21:9, s. 1870-1876
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Tidskriftsartikel (refereegranskat)abstract
- Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3 weeks: cohort A, 200 mg/m(2) (n = 15); cohort B, 375 mg/m(2) (n = 16); cohort C, first dose 375 mg/m(2), seven subsequent doses of 750 mg/m(2) (n = 16). Patients were assessed for safety, efficacy, pharmacodynamics and pharmacokinetics. Results: The median patient age was 58 years, the majority had Ann Arbor stage III/IV disease and had received a median of 2 (range 1-6) prior regimens. Ocrelizumab was well tolerated with grade 3/4 toxicity occurring in 9% of patients. The most common toxicity was infusion-related reactions (74% patients), all grade 1/2 except one grade 3 event. The objective response rate was 38% and was similar in patients with low-affinity and high-affinity variants of the Fc gamma receptor IIIa (Fc gamma RIIIa). With follow-up of similar to 28 months, the median progression-free survival was 11.4 months. Conclusion: Ocrelizumab demonstrated activity in patients with relapsed/refractory FL following prior rituximab treatment, with safety similar to rituximab although adverse events appeared milder.
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| 25. |
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| 26. |
- Gullberg, B., et al.
(författare)
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ALMA finds dew drops in the dusty spider's web
- 2016
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Ingår i: Astronomy and Astrophysics. - : EDP Sciences. - 0004-6361 .- 1432-0746. ; 591
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Tidskriftsartikel (refereegranskat)abstract
- We present 0 ''.5 resolution ALMA detections of the observed 246 GHz continuum, [CI] P-3(2) -> P-3(1) fine structure line ([CI] 2-1), CO(7-6), and H2O lines in the z = 2:161 radio galaxy MRC1138-262, the so-called Spiderweb galaxy. We detect strong [CI] 2-1 emission both at the position of the radio core, and in a second component similar to 4 kpc away from it. The 1100 km s(-1) broad [CI]2-1 line in this latter component, combined with its H-2 mass of 1 : 6 x 10(10) M-circle dot, implies that this emission must come from a compact region
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