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1.
  • Schael, S, et al. (författare)
  • Precision electroweak measurements on the Z resonance
  • 2006
  • Ingår i: Physics Reports. - : Elsevier BV. - 0370-1573 .- 1873-6270. ; 427:5-6, s. 257-454
  • Forskningsöversikt (refereegranskat)abstract
    • We report on the final electroweak measurements performed with data taken at the Z resonance by the experiments operating at the electron-positron colliders SLC and LEP. The data consist of 17 million Z decays accumulated by the ALEPH, DELPHI, L3 and OPAL experiments at LEP, and 600 thousand Z decays by the SLID experiment using a polarised beam at SLC. The measurements include cross-sections, forward-backward asymmetries and polarised asymmetries. The mass and width of the Z boson, m(Z) and Gamma(Z), and its couplings to fermions, for example the p parameter and the effective electroweak mixing angle for leptons, are precisely measured: m(Z) = 91.1875 +/- 0.0021 GeV, Gamma(Z) = 2.4952 +/- 0.0023 GeV, rho(l) = 1.0050 +/- 0.0010, sin(2)theta(eff)(lept) = 0.23153 +/- 0.00016. The number of light neutrino species is determined to be 2.9840 +/- 0.0082, in agreement with the three observed generations of fundamental fermions. The results are compared to the predictions of the Standard Model (SM). At the Z-pole, electroweak radiative corrections beyond the running of the QED and QCD coupling constants are observed with a significance of five standard deviations, and in agreement with the Standard Model. Of the many Z-pole measurements, the forward-backward asymmetry in b-quark production shows the largest difference with respect to its SM expectation, at the level of 2.8 standard deviations. Through radiative corrections evaluated in the framework of the Standard Model, the Z-pole data are also used to predict the mass of the top quark, m(t) = 173(+10)(+13) GeV, and the mass of the W boson, m(W) = 80.363 +/- 0.032 GeV. These indirect constraints are compared to the direct measurements, providing a stringent test of the SM. Using in addition the direct measurements of m(t) and m(W), the mass of the as yet unobserved SM Higgs boson is predicted with a relative uncertainty of about 50% and found to be less than 285 GeV at 95% confidence level. (c) 2006 Elsevier B.V. All rights reserved.
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3.
  • Klionsky, Daniel J., et al. (författare)
  • Guidelines for the use and interpretation of assays for monitoring autophagy
  • 2012
  • Ingår i: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 8:4, s. 445-544
  • Forskningsöversikt (refereegranskat)abstract
    • In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
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4.
  • The Seventeenth Data Release of the Sloan Digital Sky Surveys : Complete Release of MaNGA, MaStar, and APOGEE-2 Data
  • 2022
  • Ingår i: Astrophysical Journal Supplement Series. - : Institute of Physics (IOP). - 0067-0049 .- 1538-4365. ; 259:2
  • Tidskriftsartikel (refereegranskat)abstract
    • This paper documents the seventeenth data release (DR17) from the Sloan Digital Sky Surveys; the fifth and final release from the fourth phase (SDSS-IV). DR17 contains the complete release of the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, which reached its goal of surveying over 10,000 nearby galaxies. The complete release of the MaNGA Stellar Library accompanies this data, providing observations of almost 30,000 stars through the MaNGA instrument during bright time. DR17 also contains the complete release of the Apache Point Observatory Galactic Evolution Experiment 2 survey that publicly releases infrared spectra of over 650,000 stars. The main sample from the Extended Baryon Oscillation Spectroscopic Survey (eBOSS), as well as the subsurvey Time Domain Spectroscopic Survey data were fully released in DR16. New single-fiber optical spectroscopy released in DR17 is from the SPectroscipic IDentification of ERosita Survey subsurvey and the eBOSS-RM program. Along with the primary data sets, DR17 includes 25 new or updated value-added catalogs. This paper concludes the release of SDSS-IV survey data. SDSS continues into its fifth phase with observations already underway for the Milky Way Mapper, Local Volume Mapper, and Black Hole Mapper surveys.
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6.
  • Chiang, Michael F., et al. (författare)
  • International Classification of Retinopathy of Prematurity, Third Edition
  • 2021
  • Ingår i: Ophthalmology. - : Elsevier. - 0161-6420 .- 1549-4713. ; 128:10, s. 51-68
  • Tidskriftsartikel (refereegranskat)abstract
    • Purpose: The International Classification of Retinopathy of Prematurity is a consensus statement that creates a standard nomenclature for classification of retinopathy of prematurity (ROP). It was initially published in 1984, expanded in 1987, and revisited in 2005. This article presents a third revision, the International Classification of Retinopathy of Prematurity, Third Edition (ICROP3), which is now required because of challenges such as: (1) concerns about subjectivity in critical elements of disease classification; (2) innovations in ophthalmic imaging; (3) novel pharmacologic therapies (e.g., antievascular endothelial growth factor agents) with unique regression and reactivation features after treatment compared with ablative therapies; and (4) recognition that patterns of ROP in some regions of the world do not fit neatly into the current classification system.Design: Review of evidence-based literature, along with expert consensus opinion. Participants: International ROP expert committee assembled in March 2019 representing 17 countries and comprising 14 pediatric ophthalmologists and 20 retinal specialists, as well as 12 women and 22 men.Methods: The committee was initially divided into 3 subcommittees-acute phase, regression or reactivation, and imaging-each of which used iterative videoconferences and an online message board to identify key challenges and approaches. Subsequently, the entire committee used iterative videoconferences, 2 in-person multiday meetings, and an online message board to develop consensus on classification.Main Outcome Measures: Consensus statement.Results: The ICROP3 retains current definitions such as zone (location of disease), stage (appearance of disease at the avascular-vascular junction), and circumferential extent of disease. Major updates in the ICROP3 include refined classification metrics (e.g., posterior zone II, notch, subcategorization of stage 5, and recognition that a continuous spectrum of vascular abnormality exists from normal to plus disease). Updates also include the definition of aggressive ROP to replace aggressive-posterior ROP because of increasing recognition that aggressive disease may occur in larger preterm infants and beyond the posterior retina, particularly in regions of the world with limited resources. ROP regression and reactivation are described in detail, with additional description of long-term sequelae.Conclusions: These principles may improve the quality and standardization of ROP care worldwide and may provide a foundation to improve research and clinical care.
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7.
  • Feng, Shaohong, et al. (författare)
  • Dense sampling of bird diversity increases power of comparative genomics
  • 2020
  • Ingår i: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 587:7833
  • Tidskriftsartikel (refereegranskat)abstract
    • Whole-genome sequencing projects are increasingly populating the tree of life and characterizing biodiversity(1-4). Sparse taxon sampling has previously been proposed to confound phylogenetic inference(5), and captures only a fraction of the genomic diversity. Here we report a substantial step towards the dense representation of avian phylogenetic and molecular diversity, by analysing 363 genomes from 92.4% of bird families-including 267 newly sequenced genomes produced for phase II of the Bird 10,000 Genomes (B10K) Project. We use this comparative genome dataset in combination with a pipeline that leverages a reference-free whole-genome alignment to identify orthologous regions in greater numbers than has previously been possible and to recognize genomic novelties in particular bird lineages. The densely sampled alignment provides a single-base-pair map of selection, has more than doubled the fraction of bases that are confidently predicted to be under conservation and reveals extensive patterns of weak selection in predominantly non-coding DNA. Our results demonstrate that increasing the diversity of genomes used in comparative studies can reveal more shared and lineage-specific variation, and improve the investigation of genomic characteristics. We anticipate that this genomic resource will offer new perspectives on evolutionary processes in cross-species comparative analyses and assist in efforts to conserve species. A dataset of the genomes of 363 species from the Bird 10,000 Genomes Project shows increased power to detect shared and lineage-specific variation, demonstrating the importance of phylogenetically diverse taxon sampling in whole-genome sequencing.
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8.
  • Jensen, Hannes, et al. (författare)
  • Probing reionization with LOFAR using 21-cm redshift space distortions
  • 2013
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 435:1, s. 460-474
  • Tidskriftsartikel (refereegranskat)abstract
    • One of the most promising ways to study the epoch of reionization (EoR) is through radio observations of the redshifted 21-cm line emission from neutral hydrogen. These observations are complicated by the fact that the mapping of redshifts to line-of-sight positions is distorted by the peculiar velocities of the gas. Such distortions can be a source of error if they are not properly understood, but they also encode information about cosmology and astrophysics. We study the effects of redshift space distortions on the power spectrum of 21-cm radiation from the EoR using large-scale N-body and radiative transfer simulations. We quantify the anisotropy introduced in the 21-cm power spectrum by redshift space distortions and show how it evolves as reionization progresses and how it relates to the underlying physics. We go on to study the effects of redshift space distortions on LOFAR observations, taking instrument noise and foreground subtraction into account. We find that LOFAR should be able to directly observe the power spectrum anisotropy due to redshift space distortions at spatial scales around k similar to 0.1 Mpc(-1) after greater than or similar to 1000 h of integration time. At larger scales, sample errors become a limiting factor, while at smaller scales detector noise and foregrounds make the extraction of the signal problematic. Finally, we show how the astrophysical information contained in the evolution of the anisotropy of the 21-cm power spectrum can be extracted from LOFAR observations, and how it can be used to distinguish between different reionization scenarios.
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9.
  • Iliev, Ilian T., et al. (författare)
  • Cosmological radiative transfer comparison project - II. The radiation-hydrodynamic tests
  • 2009
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; , s. 1313-
  • Tidskriftsartikel (refereegranskat)abstract
    • The development of radiation hydrodynamical methods that are able to follow gas dynamics and radiative transfer (RT) self-consistently is key to the solution of many problems in numerical astrophysics. Such fluid flows are highly complex, rarely allowing even for approximate analytical solutions against which numerical codes can be tested. An alternative validation procedure is to compare different methods against each other on common problems, in order to assess the robustness of the results and establish a range of validity for the methods. Previously, we presented such a comparison for a set of pure RT tests (i.e. for fixed, non-evolving density fields). This is the second paper of the Cosmological Radiative Transfer Comparison Project, in which we compare nine independent RT codes directly coupled to gas dynamics on three relatively simple astrophysical hydrodynamics problems: (i) the expansion of an HII region in a uniform medium, (ii) an ionization front in a 1/r2 density profile with a flat core and (iii) the photoevaporation of a uniform dense clump. Results show a broad agreement between the different methods and no big failures, indicating that the participating codes have reached a certain level of maturity and reliability. However, many details still do differ, and virtually every code has showed some shortcomings and has disagreed, in one respect or another, with the majority of the results. This underscores the fact that no method is universal and all require careful testing of the particular features which are most relevant to the specific problem at hand.
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10.
  • Jarvis, Erich D., et al. (författare)
  • Whole-genome analyses resolve early branches in the tree of life of modern birds
  • 2014
  • Ingår i: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 346:6215, s. 1320-1331
  • Tidskriftsartikel (refereegranskat)abstract
    • To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handle genome-scale data. We recovered a highly resolved tree that confirms previously controversial sister or close relationships. We identified the first divergence in Neoaves, two groups we named Passerea and Columbea, representing independent lineages of diverse and convergently evolved land and water bird species. Among Passerea, we infer the common ancestor of core landbirds to have been an apex predator and confirm independent gains of vocal learning. Among Columbea, we identify pigeons and flamingoes as belonging to sister clades. Even with whole genomes, some of the earliest branches in Neoaves proved challenging to resolve, which was best explained by massive protein-coding sequence convergence and high levels of incomplete lineage sorting that occurred during a rapid radiation after the Cretaceous-Paleogene mass extinction event about 66 million years ago.
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11.
  • Ahn, Kyungjin, et al. (författare)
  • DETECTING THE RISE AND FALL OF THE FIRST STARS BY THEIR IMPACT ON COSMIC REIONIZATION
  • 2012
  • Ingår i: The Astrophysical Journal Letters. - 2041-8205. ; 756:1, s. L16-
  • Tidskriftsartikel (refereegranskat)abstract
    • The intergalactic medium was reionized before redshift z similar to 6, most likely by starlight which escaped from early galaxies. The very first stars formed when hydrogen molecules (H-2) cooled gas inside the smallest galaxies, minihalos (MHs) of mass between 10(5) and 10(8) M-circle dot. Although the very first stars began forming inside these MHs before redshift z similar to 40, their contribution has, to date, been ignored in large-scale simulations of this cosmic reionization. Here we report results from the first reionization simulations to include these first stars and the radiative feedback that limited their formation, in a volume large enough to follow the crucial spatial variations that influenced the process and its observability. We show that, while MH stars stopped far short of fully ionizing the universe, reionization began much earlier with MH sources than without, and was greatly extended, which boosts the intergalactic electron-scattering optical depth and the large-angle polarization fluctuations of the cosmic microwave background significantly. This boost should be readily detectable by Planck, although within current Wilkinson Microwave Anisotropy Probe uncertainties. If reionization ended as late as z(ov) less than or similar to 7, as suggested by other observations, Planck will thereby see the signature of the first stars at high redshift, currently undetectable by other probes.
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12.
  • Ahn, Kyungjin, et al. (författare)
  • The Inhomogeneous Background Of H2-Dissociating Radiation During Cosmic Reionization
  • 2009
  • Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 695, s. 1430-1445
  • Tidskriftsartikel (refereegranskat)abstract
    • The first, self-consistent calculations are presented of the cosmological, H2-dissociating UV background produced during the epoch of reionization by the sources of reionization. Large-scale radiative transfer simulations of reionization trace the impact of all the ionizing starlight on the intergalactic medium (IGM) from all the sources in our simulation volume down to dwarf galaxies of mass ~108 M sun, identified by very high resolution N-body simulations, including the self-regulating effect of IGM photoheating on dwarf galaxy formation. The UV continuum emitted below 13.6 eV by each source is then transferred through the same IGM, attenuated by atomic H Lyman series resonance lines, to predict the evolution of the inhomogeneous radiation background in the Lyman-Werner (LW) bands of H2 between 11 and 13.6 eV. On average, the intensity of this LW background is found to rise to the threshold level at which dissociation suppresses H2 cooling and star formation inside minihalos, long before reionization is complete. Spatial variations in the LW background are found which result from the clustering of sources associated with large-scale structure formation, such that intensity fluctuations correlate with matter density fluctuations. As a result, the LW background rises to the threshold level for H2 suppression earlier in the vicinity of the reionization sources and their H II regions.
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13.
  • Ahn, Kyungjin, et al. (författare)
  • The Inhomogeneous Background of H2 Dissociating Radiation During Cosmic Reionization
  • 2008
  • Ingår i: FIRST STARS III. - : American Institute of Physics.
  • Konferensbidrag (refereegranskat)abstract
    • The first, self-consistent calculations of the cosmological H2 dissociating UV background produced during the epoch of reionization by the sources of reionization are presented. Large-scale radiative transfer simulations of reionization trace the impact of all the ionizing starlight on the IGM from all sources in our simulation volume down to dwarf galaxies of mass ~108 Msolar, identified by very high-resolution N-body simulations, including the self-regulating effect of IGM photoheating on dwarf galaxy formation. The UV continuum emitted below 13.6 eV by each source is then transferred through the same IGM, attenuated by atomic H Lyman series resonance lines, to predict the evolution of the inhomogeneous background in the Lyman-Werner band of H2 between 11 and 13.6 eV.
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14.
  • Ahn, Kyungjin, et al. (författare)
  • The Inhomogeneous Background of Hydrogen-Molecule Dissociating Radiation during Cosmic Reionization
  • 2008
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • The first, self-consistent calculations are presented of the cosmological, H2-dissociating UV background produced during the epoch of reionization by the sources of reionization. Large-scale radiative transfer simulations of reionization trace the impact of all the ionizing starlight on the IGM from all the sources in our simulation volume down to dwarf galaxies of mass ~10^8 Msun, identified by very high-resolution N-body simulations, including the self-regulating effect of IGM photoheating on dwarf galaxy formation. The UV continuum emitted below 13.6 eV by each source is then transferred through the same IGM, attenuated by atomic H Lyman series resonance lines, to predict the evolution of the inhomogeneous radiation background in the Lyman-Werner bands of H2 between 11 and 13.6 eV. On average, the intensity of this Lyman-Werner background is found to rise to the threshold level at which dissociation suppresses H2 cooling and star formation inside minihalos, long before reionization is complete. Spatial variations in the Lyman-Werner background are found which result from the clustering of sources associated with large-scale structure formation, such that intensity fluctuations correlate with matter density fluctuations. As a result, the Lyman-Werner background rises to the threshold level for H2 suppression earlier in the vicinity of the reionization sources and their H II regions.
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15.
  • Bianco, Michele, et al. (författare)
  • The impact of inhomogeneous subgrid clumping on cosmic reionization - II. Modelling stochasticity
  • 2021
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 504:2, s. 2443-2460
  • Tidskriftsartikel (refereegranskat)abstract
    • Small-scale density fluctuations can significantly affect reionization, but are typically modelled quite crudely. Unresolved fluctuations in numerical simulations and analytical calculations are included using a gas clumping factor, typically assumed to be independent of the local environment. In Paper I, we presented an improved, local density-dependent model for the sub-grid gas clumping. Here, we extend this using an empirical stochastic model based on the results from high-resolution numerical simulations which fully resolve all relevant fluctuations. Our model reproduces well both the mean density-clumping relation and its scatter. We applied our stochastic model, along with the mean clumping one and the Paper I deterministic model, to create large-volume realizations of the clumping field, and used these in radiative transfer simulations of cosmic reionization. Our results show that the simplistic mean clumping model delays reionization compared to local density-dependent models, despite producing fewer recombinations overall. This is due to the very different spatial distribution of clumping, resulting in much higher photoionization rates in the latter cases. The mean clumping model produces smaller H II regions throughout most of reionization, but those percolate faster at late times. It also causes a significant delay in the 21-cm fluctuations peak and yields lower non-Gaussianity and many fewer bright pixels in the PDF distribution. The stochastic density-dependent model shows relatively minor differences from the deterministic one, mostly concentrated around overlap, where it significantly suppresses the 21-cm fluctuations, and at the bright tail of the 21-cm PDFs, where it produces noticeably more bright pixels.
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16.
  • Datta, Kanan K., et al. (författare)
  • Light-cone effect on the reionization 21-cm power spectrum
  • 2012
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 424:3, s. 1877-1891
  • Tidskriftsartikel (refereegranskat)abstract
    • Observations of redshifted 21-cm radiation from neutral hydrogen during the epoch of reionization are considered to constitute the most promising tool to probe that epoch. One of the major goals of the first generation of low-frequency radio telescopes is to measure the 3D 21-cm power spectrum. However, the 21-cm signal could evolve substantially along the line-of-sight (LOS) direction of an observed 3D volume, since the received signal from different planes transverses to the LOS originated from different look-back times and could therefore be statistically different. Using numerical simulations we investigate this so-called light-cone effect on the spherically averaged 3D 21-cm power spectrum. For this version of the power spectrum, we find that the effect mostly averages out and observe a smaller change in the power spectrum compared to the amount of evolution in the mean 21-cm signal and its rms variations along the LOS direction. Nevertheless, changes up to similar to 50?per cent at large scales are possible. In general, the power is enhanced/suppressed at large/small scales when the effect is included. The cross-over mode below/above which the power is enhanced/suppressed moves towards larger scales as reionization proceeds. When considering the 3D power spectrum we find it to be anisotropic at the late stages of reionization and on large scales. The effect is dominated by the evolution of the ionized fraction of hydrogen during reionization and including peculiar velocities hardly changes these conclusions. We present simple analytical models which explain qualitatively all the features we see in the simulations.
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17.
  • Datta, Kanan K., et al. (författare)
  • Light cone effect on the reionization 21-cm signal - II. Evolution, anisotropies and observational implications
  • 2014
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 442:2, s. 1491-1506
  • Tidskriftsartikel (refereegranskat)abstract
    • Measurements of the H i 21-cm power spectra from the reionization epoch will be influenced by the evolution of the signal along the line-of-sight direction of any observed volume. We use numerical as well as seminumerical simulations of reionization in a cubic volume of 607 Mpc across to study this so-called light-cone effect on the H i 21-cm power spectrum. We find that the light-cone effect has the largest impact at two different stages of reionization: one when reionization is similar to 20 per cent and other when it is similar to 80 per cent completed. We find a factor of similar to 4 amplification of the power spectrum at the largest scale available in our simulations. We do not find any significant anisotropy in the 21-cm power spectrum due to the light-cone effect. We argue that for the power spectrum to become anisotropic, the light-cone effect would have to make the ionized bubbles significantly elongated or compressed along the line of sight, which would require extreme reionization scenarios. We also calculate the two-point correlation functions parallel and perpendicular to the line of sight and find them to differ. Finally, we calculate an optimum frequency bandwidth below which the light-cone effect can be neglected when extracting power spectra from observations. We find that if one is willing to accept a 10 per cent error due to the light-cone effect, the optimum frequency bandwidth for k = 0.056 Mpc(-1) is similar to 7.5 MHz. For k = 0.15 and 0.41 Mpc(-1), the optimum bandwidth is similar to 11 and similar to 16 MHz, respectively.
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18.
  • Datta, Kanan K., et al. (författare)
  • Prospects of observing a quasar H ii region during the epoch of reionization with the redshifted 21-cm signal
  • 2012
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 424:1, s. 762-778
  • Tidskriftsartikel (refereegranskat)abstract
    • We present a study of the impact of a bright quasar on the redshifted 21-cm signal during the epoch of reionization (EoR). Using three different cosmological radiative transfer simulations, we investigate if quasars are capable of substantially changing the size and morphology of the H ii regions they are born in. We choose stellar and quasar luminosities in a way that is favourable to seeing such an effect. We find that even the most luminous of our quasar models is not able to increase the size of its native H ii region substantially beyond those of large H ii regions produced by clustered stellar sources alone. However, the quasar H ii region is found to be more spherical. We next investigate the prospects of detecting such H ii regions in the redshifted 21-cm data from the Low Frequency Array (LOFAR) by means of a matched filter technique. We find that H ii regions with radii similar to 25 comoving Mpc or larger should have a sufficiently high detection probability for 1200 h of integration time. Although the matched filter can in principle distinguish between more and less spherical regions, we find that when including realistic system noise this distinction can no longer be made. The strong foregrounds are found not to pose a problem for the matched filter technique. We also demonstrate that when the quasar position is known, the redshifted 21-cm data can still be used to set upper limits on the ionizing photon rate of the quasar. If both the quasar position and its luminosity are known, the redshifted 21-cm data can set new constraints on quasar lifetimes.
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19.
  • Dixon, Keri L., et al. (författare)
  • The large-scale observational signatures of low-mass galaxies during reionization
  • 2016
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 456:3, s. 3011-3029
  • Tidskriftsartikel (refereegranskat)abstract
    • Observations of the epoch of reionization give us clues about the nature and evolution of the sources of ionizing photons, or early stars and galaxies. We present a new suite of structure formation and radiative transfer (RT) simulations from the PRACE4LOFAR project designed to investigate whether the mechanism of radiative feedback, or the suppression of star formation in ionized regions from UV radiation, can be inferred from these observations. Our source halo mass extends down to 10(8) M-circle dot, with sources in the mass range 10(8)-10(9) M-circle dot expected to be particularly susceptible to feedback from ionizing radiation, and we vary the aggressiveness and nature of this suppression. Not only do we have four distinct source models, we also include two box sizes (67 and 349 Mpc), each with two grid resolutions. This suite of simulations allows us to investigate the robustness of our results. All of our simulations are broadly consistent with the observed electron-scattering optical depth of the cosmic microwave background and the neutral fraction and photoionization rate of hydrogen at z similar to 6. In particular, we investigate the redshifted 21-cm emission in anticipation of upcoming radio interferometer observations. We find that the overall shape of the 21-cm signal and various statistics are robust to the exact nature of source suppression, the box size, and the resolution. There are some promising model discriminators in the non-Gaussianity and small-scale power spectrum of the 21-cm signal.
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20.
  • Friedrich, Martina M., 1982-, et al. (författare)
  • Radiative Transfer of energetic photons : X-rays and helium ionization in C2-Ray
  • 2012
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 421:3, s. 2232-2250
  • Tidskriftsartikel (refereegranskat)abstract
    • We present an extension to the short-characteristic ray-tracing and non-equilibrium photoionization code C2-RAY. The new version includes the effects of helium and improved multifrequency heating. The motivation for this work is to be able to deal with harder ionizing spectra, such as from quasar-like sources during cosmic reionization. We review the basic algorithmic ingredients of C2-RAY before describing the changes implemented, which include a treatment of the full on-the-spot (OTS) approximation, secondary ionization, and multifrequency photoionization and heating. We performed a series of tests against equilibrium solutions from CLOUDY as well as comparisons to the hydrogen-only solutions by C2-RAY in the extensive cosmological radiative transfer code comparison project. We show that the full, coupled OTS approximation is more accurate than the simplified, uncoupled one. We find that also with helium and a multifrequency setup, long time-steps (up to ~10 per cent of the recombination time) still give accurate results for the ionization fractions. On the other hand, accurate results for the temperature set strong constraints on the time-step. The details of these constraints depend, however, on the optical depth of the cells. We use the new version of the code to confirm that the assumption made in many reionization simulations, namely that helium is singly ionized everywhere where hydrogen is, is indeed valid when the sources have stellar-like spectra.
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21.
  • Friedrich, Martina M., et al. (författare)
  • Topology and sizes of H II regions during cosmic reionization
  • 2011
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 413:2, s. 1353-1372
  • Tidskriftsartikel (refereegranskat)abstract
    • We use the results of large-scale simulations of reionization to explore methods for characterizing the topology and sizes of H ii regions during reionization. We use four independent methods for characterizing the sizes of ionized regions. Three of them give us a full size distribution: the friends-of-friends (FoF) method, the spherical average (SPA) method and the power spectrum (PS) of the ionized fraction. The latter three methods are complementary: while the FoF method captures the size distribution of the small-scale H ii regions, which contribute only a small amount to the total ionization fraction, the SPA method provides a smoothed measure for the average size of the H ii regions constituting the main contribution to the ionized fraction, and the PS does the same while retaining more details on the size distribution. Our fourth method for characterizing the sizes of the H ii regions is the average size which results if we divide the total volume of the H ii regions by their total surface area (i.e. 3V/A), computed in terms of the ratio of the corresponding Minkowski functionals of the ionized fraction field. To characterize the topology of the ionized regions, we calculate the evolution of the Euler characteristic. We find that the evolution of the topology during the first half of reionization is consistent with inside-out reionization of a Gaussian density field. We use these techniques to investigate the dependence of the size and topology on some basic source properties, such as the halo mass-to-light ratio, susceptibility of haloes to negative feedback from reionization and the minimum halo mass for sources to form. We find that the suppression of ionizing sources within ionized regions slows the growth of H ii regions and also changes their size distribution. Additionally, the topology of simulations including suppression is more complex, as indicated by the evolution of the Euler characteristic of the ionized regions. We find the density and ionized fraction to be correlated on large scales, in agreement with the inside-out picture of reionization.
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22.
  • Ichikawa, Kazuhide, et al. (författare)
  • Measuring the history of cosmic reionization using the 21-cm probability distribution function from simulations
  • 2010
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 406:4, s. 2521-2532
  • Tidskriftsartikel (refereegranskat)abstract
    • The 21-cm probability distribution function (PDF; i.e. distribution of pixel brightness temperatures) is expected to be highly non-Gaussian during reionization and to provide important information on the distribution of density and ionization. We measure the 21-cm PDF as a function of redshift in a large simulation of cosmic reionization and propose a simple empirical fit. Guided by the simulated PDF, we then carry out a maximum likelihood analysis of the ability of upcoming experiments to measure the shape of the 21-cm PDF and derive from it the cosmic reionization history. Under the strongest assumptions, we find that upcoming experiments can measure the reionization history in the mid to late stages of reionization to 1-10 per cent accuracy. Under a more flexible approach that allows for four free parameters at each redshift, a similar accuracy requires the lower noise levels of second-generation 21-cm experiments.
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23.
  • Iliev, Ilian T., et al. (författare)
  • Can 21-cm observations discriminate between high-mass and low-mass galaxies as reionization sources?
  • 2012
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 423:3, s. 2222-2253
  • Tidskriftsartikel (refereegranskat)abstract
    • The prospect of detecting the first galaxies by observing their impact on the intergalactic medium (IGM) as they reionized it during the first billion years leads us to ask whether such indirect observations are capable of diagnosing which types of galaxies were most responsible for reionization. We attempt to answer this with new large-scale radiative transfer simulations of reionization including the entire mass range of atomically cooling haloes (M > 108 M?). We divide these haloes into two groups, high-mass, atomically cooling haloes, or HMACHs (M > 109 M?), and low-mass, atomically cooling haloes, or LMACHs (108 < M < 109 M?), the latter being susceptible to negative feedback due to Jeans mass filtering in ionized regions, which leads to a process we refer to as self-regulation. We focus here on predictions of the redshifted 21-cm emission, to see if upcoming observations are capable of distinguishing a universe ionized primarily by HMACHs from one in which both HMACHs and LMACHs are responsible, and to see how these results depend upon the uncertain source efficiencies. We find that 21-cm fluctuation power spectra observed by the first-generation Epoch of Reionization 21-cm radio interferometer arrays should be able to distinguish the case of reionization by HMACHs alone from that by both HMACHs and LMACHs, together. Some reionization scenarios, e.g. one with abundant low-efficiency sources versus one with self-regulation, yield very similar power spectra and rms evolution and thus can only be discriminated by their different mean reionization history and 21-cm probability distribution function (PDF) distributions. We also find that the skewness of the 21-cm PDF distribution smoothed with Low Frequency Array (LOFAR)-like resolution shows a clear feature correlated with the rise of the rms due to patchiness. This is independent of the reionization scenario and thus provides a new approach for detecting the rise of large-scale patchiness. The peak epoch of the 21-cm rms fluctuations depends significantly on the beam and bandwidth smoothing size as well as on the reionization scenario and can occur for ionized fractions as low as 30 per cent and as high as 70 per cent. Measurements of the mean photoionization rates are sensitive to the average density of the regions being studied and therefore could be strongly skewed in certain cases. Finally, the simulation volume employed has very modest effects on the results during the early and intermediate stages of reionization, but late-time signatures could be significantly affected.
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24.
  • Iliev, Ilian T., et al. (författare)
  • Current models of the observable consequences of cosmic reionization and their detectability
  • 2008
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Blackwell Publishing. - 0035-8711 .- 1365-2966. ; 384:3, s. 863-874
  • Tidskriftsartikel (refereegranskat)abstract
    • A number of large current experiments aim to detect the signatures of the cosmic reionization at redshifts z > 6. Their success depends crucially on understanding the character of the reionization process and its observable consequences and designing the best strategies to use. We use large-scale simulations of cosmic reionization to evaluate the reionization signatures at redshifted 21-cm and small-scale cosmic microwave background (CMB) anisotropies in the best current model for the background universe, with fundamental cosmological parameters given by Wilkinson Microwave Anisotropy Probe three-year results. We find that the optimal frequency range for observing the ‘global step’ of the 21-cm emission is 120–150 MHz, while statistical studies should aim at 140–160 MHz, observable by GMRT. Some strongly non-Gaussian brightness features should be detectable at frequencies up to ∼190 MHz. In terms of sensitivity-signal trade-off relatively low resolutions, corresponding to beams of at least a few arcminutes, are preferable. The CMB anisotropy signal from the kinetic Sunyaev–Zel'dovich effect from reionized patches peaks at tens of μK at arcminute scales and has an rms of ∼1 μK, and should be observable by the Atacama Cosmology Telescope and the South Pole Telescope. We discuss the various observational issues and the uncertainties involved, mostly related to the poorly known reionization parameters and, to a lesser extend, to the uncertainties in the background cosmology.
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25.
  • Iliev, Ilian T., et al. (författare)
  • kSZ from patchy reionization: The view from the simulations
  • 2006
  • Ingår i: New Astronomy Reviews. - : Elsevier BV. - 1387-6473. ; 50:11-12, s. 909-917
  • Tidskriftsartikel (refereegranskat)abstract
    • We present the first calculation of the kinetic Sunyaev Zel’dovich (kSZ) effect due to the inhomogeneus reionization of the universe based on detailed large-scale radiative transfer simulations of reionization. The resulting sky power spectra peak at ℓ = 2000 8000 with maximum values of [ℓ(ℓ + 1)Cℓ/(2π)]max ˜ 4 7 × 10^‑13. The scale roughly corresponds to the typical ionized bubble sizes observed in our simulations, of ˜5 20 Mpc. The kSZ anisotropy signal from reionization dominates the primary CMB signal above ℓ = 3000. At large-scales the patchy kSZ signal depends only on the source efficiencies. It is higher when sources are more efficient at producing ionizing photons, since such sources produce larger ionized regions, on average, than less efficient sources. The introduction of sub-grid gas clumping in the radiative transfer simulations produce significantly more power at small-scales, but has little effect at large-scales. The patchy reionization kSZ signal is dominated by the post-reionization signal from fully-ionized gas, but the two contributions are of similar order at scales ℓ ˜ 3000 ‑ 10^4, indicating that the kSZ anisotropies from reionization are an important component of the total kSZ signal at these scales.
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26.
  • Iliev, Ilian T., et al. (författare)
  • Reionization : characteristic scales, topology and observability
  • 2009
  • Ingår i: Astrophysics and Space Science. - : Springer Science and Business Media LLC. - 0004-640X .- 1572-946X. ; 320:1-3, s. 39-43
  • Tidskriftsartikel (refereegranskat)abstract
    • Recently the numerical simulations of the process of reionization of the universe at z>6 have made a qualitative leap forward, reaching sufficient sizes and dynamic range to determine the characteristic scales of this process. This allowed making the first realistic predictions for a variety of observational signatures. We discuss recent results from large-scale radiative transfer and structure formation simulations on the observability of high-redshift Ly- α sources. We also briefly discuss the dependence of the characteristic scales and topology of the ionized and neutral patches on the reionization parameters.
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27.
  • Iliev, Ilian T., et al. (författare)
  • Self-Regulated Reionization
  • 2007
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 376:2, s. 534-548
  • Tidskriftsartikel (refereegranskat)abstract
    • Recently, we have presented the first, truly large-scale radiative transfer simulations of inhomogeneous cosmic reionization which resolve all the possible halo sources down to the dwarf galaxy mass range, M > 109 Mo, in a comoving volume (100 h-1 Mpc)3. This is large enough to sample the global mean history, geometry and statistical properties of reionization fairly and accurately for the first time. Here we present new simulations which extend the source halo mass range downward to 108 Mo, to capture the full range of halo masses thought to be primarily responsible for reionization by their star formation following atomic hydrogen radiative cooling and gravitational collapse. Haloes below about 109 Mo, however, are subject to Jeans-mass filtering in the ionized regions, which suppresses their baryonic content and their ability to release ionizing radiation. By including these smaller mass haloes but accounting for their suppression, too, we find that reionization is ‘self-regulating’, as follows. As the mean ionized fraction rises, so does the fraction of the volume within which suppression occurs. Hence, the degree of suppression is related to the mean ionized fraction. Since low-mass haloes with high efficiency (i.e. high emissivity) achieve a given mean ionized fraction earlier than do those with low efficiency, Jeans-mass filtering compensates for the difference in the emissivity of the suppressible haloes in these two cases. As a result, in the presence of lower mass source haloes, reionization begins earlier, but the later stages of reionization and the time of overlap are dictated by the efficiency of the higher mass haloes, independent of the efficiency of the suppressible, lower mass haloes. Hence, while the lower mass haloes do not alter the overlap redshift, zov, they serve to boost the electron-scattering optical depth of the universe, τes. This may explain why observations of quasar absorption spectra at high redshift find that reionization ended late (zov < 7), while cosmic microwave background polarization measurements report a large enough τes that reionization must have begun much earlier (z > 11). We present results for the Lambda cold dark matter universe with cosmological parameters from both 1- and 3-yr data releases of Wilkinson Microwave Anisotropy Probe. Reionization histories consistent with current constraints on zov and τes are shown to be achievable with standard stellar sources in haloes above 108 Mo. Neither minihaloes nor exotic sources are required, and the phenomenon of ‘double reionization’ previously suggested does not occur.
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28.
  • Iliev, Ilian T., et al. (författare)
  • Simulating cosmic reionization : how large a volume is large enough?
  • 2014
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 439:1, s. 725-743
  • Tidskriftsartikel (refereegranskat)abstract
    • We present the largest-volume (425 Mpc h(-1) = 607 Mpc on a side) full radiative transfer simulation of cosmic reionization to date. We show that there is significant additional power in density fluctuations at very large scales. We systematically investigate the effects this additional power has on the progress, duration and features of reionization and on selected reionization observables. We find that comoving volume of similar to 100 Mpc h(-1) per side is sufficient for deriving a convergent mean reionization history, but that the reionization patchiness is significantly underestimated. We use jackknife splitting to quantify the convergence of reionization properties with simulation volume. We find that sub-volumes of similar to 100 Mpc h(-1) per side or larger yield convergent reionization histories, except for the earliest times, but smaller volumes of similar to 50 Mpc h(-1) or less are not well converged at any redshift. Reionization history milestones show significant scatter between the sub-volumes, as high as Delta z similar to 1 for similar to 50 Mpc h(-1) volumes. If we only consider mean-density sub-regions the scatter decreases, but remains at Delta z similar to 0.1-0.2 for the different size sub-volumes. Consequently, many potential reionization observables like 21-cm rms, 21-cm PDF skewness and kurtosis all showgood convergence for volumes of similar to 200 Mpc h(-1), but retain considerable scatter for smaller volumes. In contrast, the three-dimensional 21-cm power spectra at large scales (k < 0.25 h Mpc(-1)) do not fully converge for any sub-volume size. These additional large-scale fluctuations significantly enhance the 21-cm fluctuations, which should improve the prospects of detection considerably, given the lower foregrounds and greater interferometer sensitivity at higher frequencies.
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29.
  • Iliev, Ilian T., et al. (författare)
  • Simulating Cosmic Reionization
  • 2008
  • Annan publikation (övrigt vetenskapligt/konstnärligt)abstract
    • The Cosmic Dark Ages and the Epoch of Reionization constitute a crucial missing link in our understanding of the evolution of the intergalactic medium and the formation and evolution of galaxies. Due to the complex nature of this global process it is best studied through large-scale numerical simulations. This presents considerable computational challenges. The dominant contributors of ionizing radiation were dwarf galaxies. These tiny galaxies must be resolved in very large cosmological volumes in order to derive their clustering properties and the corresponding observational signatures correctly, which makes this one of the most challenging problems of numerical cosmology. We have recently performed the largest and most detailed simulations of the formation of early cosmological large-scale structures and their radiative feedback leading to cosmic reionization. This was achieved by running extremely large (up to 29 billion-particle) N-body simulations of the formation of the Cosmic Web, with enough particles and sufficient force resolution to resolve all the galactic halos with total masses larger than 10^8 Solar masses in computational volumes of up to (163 Mpc)^3. These results were then post-processed by propagating the ionizing radiation from all sources by using fast and accurate ray-tracing radiative transfer method. Both of our codes are parallelized using a combination of MPI and OpenMP and to this date have been run efficiently on up to 2048 cores (N-body) and up to 10000 cores (radiative transfer) on the newly-deployed Sun Constellation Linux Cluster at the Texas Advanced Computing Center. In this paper we describe our codes, parallelization strategies, scaling and some preliminary scientific results. (abridged)
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30.
  • Iliev, Ilian T., et al. (författare)
  • Simulating Reionization: Character and Observability
  • 2008
  • Ingår i: FIRST STARS III. - : American Institute of Physics.
  • Konferensbidrag (refereegranskat)abstract
    • In recent years there has been considerable progress in our understanding of the nature and properties of the reionization process. In particular, the numerical simulations of this epoch have made a qualitative leap forward, reaching sufficiently large scales to derive the characteristic scales of the reionization process and thus allowing for realistic observational predictions. Our group has recently performed the first such large-scale radiative transfer simulations of reionization, run on top of state-of-the-art simulations of early structure formation. This allowed us to make the first realistic observational predictions about the Epoch of Reionization based on detailed radiative transfer and structure formation simulations. We discuss the basic features of reionization derived from our simulations and some recent results on the observational implications for the high-redshift Ly-α sources.
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31.
  • Iliev, Ilian T., et al. (författare)
  • The effect of the intergalactic environment on the observability of Lyα emitters during reionization
  • 2008
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 391:1, s. 63-
  • Tidskriftsartikel (refereegranskat)abstract
    • Observations of high-redshift Lyα sources are a major tool for studying the high-redshift universe and are one of the most promising ways to constrain the later stages of reionization. The understanding and interpretation of the data is far from straightforward, however. We discuss the effect of the reionizing intergalactic medium (IGM) on the observability of Lyα sources based on large simulations of early structure formation with radiative transfer. This takes into account self-consistently the reionization history, density, velocity and ionization structures and non-linear source clustering. We find that all fields are highly anisotropic and as a consequence there are very large variations in opacity among the different lines of sight. The velocity effects, from both infall and source peculiar velocity are most important for the luminous sources, affecting the line profile and depressing the bright end of the luminosity function. The line profiles are generally asymmetric and the line centres of the luminous sources are always absorbed due to the high density of the local IGM. For both luminous and average sources the damping wing effects are of similar magnitude and remain significant until fairly late, when the IGM is ionized between 30 and 70 per cent by mass.The ionizing flux in the ionized patch surrounding a high-density peak is generally strongly dominated, particularly at late times, by the cluster of faint sources, rather than the central massive galaxy. Our results reproduce well the observed mean opacity of the IGM at z ~ 6. The IGM absorption does not change appreciably the correlation function of sources at high redshift. Our derived luminosity function assuming constant mass-to-light ratio provides an excellent match to the shape of the observed luminosity function at z = 6.6 with faint-end slope of α = -1.5. The resulting mass-to-light ratio implies that the majority of sources responsible for reionization are too faint to be observed by the current surveys.Bibtex entry for this abstract Preferred format for this abstract
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32.
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33.
  • Jensen, Hannes, et al. (författare)
  • On the use of Ly alpha emitters as probes of reionization
  • 2013
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 428:2, s. 1366-1381
  • Tidskriftsartikel (refereegranskat)abstract
    • We use numerical simulations to study the effects of the patchiness of a partly reionized intergalactic medium (IGM) on the observability of Ly alpha emitters (LAEs) at high redshifts (z greater than or similar to 6). We present a new model that divides the Ly alpha radiative transfer into a (circum) galactic and an extragalactic (IGM) part, and investigate how the choice of intrinsic line model affects the IGM transmission results. We use our model to study the impact of neutral hydrogen on statistical observables such as the Ly alpha rest-frame equivalent width (REW) distribution, the LAE luminosity function and the two-point correlation function. We find that if the observed changes in LAE luminosity functions and equivalent width distributions between z similar to 6 and 7 are to be explained by an increased IGM neutral fraction alone, we require an extremely late and rapid reionization scenario, where the Universe was similar to 40 per cent ionized at z = 7, similar to 50 per cent ionized at z = 6.5 and similar to 100 per cent ionized at z = 6. This is in conflict with other observations, suggesting that intrinsic LAE evolution at z greater than or similar to 6 cannot be completely neglected. We show how the two-point correlation function can provide more robust constraints once future observations obtain larger LAE samples, and provide predictions for the sample sizes needed to tell different reionization scenarios apart.
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34.
  • Mao, Yi, et al. (författare)
  • Redshift-space distortion of the 21-cm background from the epoch of reionization - I. Methodology re-examined
  • 2012
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 422:2, s. 926-954
  • Tidskriftsartikel (refereegranskat)abstract
    • The peculiar velocity of the intergalactic gas responsible for the cosmic 21-cm background from the epoch of reionization and beyond introduces an anisotropy in the three-dimensional power spectrum of brightness temperature fluctuations. Measurement of this anisotropy by future 21-cm surveys is a promising tool for separating cosmology from 21-cm astrophysics. However, previous attempts to model the signal have often neglected peculiar velocity or only approximated it crudely. This paper re-examines the effects of peculiar velocity on the 21-cm signal in detail, improving upon past treatment and addressing several issues for the first time. (1) We show that even the angle-averaged power spectrum, P(k), is affected significantly by the peculiar velocity. (2) We re-derive the brightness temperature dependence on atomic hydrogen density, spin temperature, peculiar velocity and its gradient and redshift to clarify the roles of thermal versus velocity broadening and finite optical depth. (3) We show that properly accounting for finite optical depth eliminates the unphysical divergence of the 21-cm brightness temperature in overdense regions of the intergalactic medium found by previous work that employed the usual optically thin approximation. (4) We find that the approximation made previously to circumvent the diverging brightness temperature problem by capping the velocity gradient can misestimate the power spectrum on all scales. (5) We further show that the observed power spectrum in redshift space remains finite even in the optically thin approximation if one properly accounts for the redshift-space distortion. However, results that take full account of finite optical depth show that this approximation is only accurate in the limit of high spin temperature. (6) We also show that the linear theory for redshift-space distortion widely employed to predict the 21-cm power spectrum results in a similar to 30 per cent error in the observationally relevant wavenumber range k similar to 0.1-1 h Mpc(-1), when strong ionization fluctuations exist (e. g. at the 50 per cent ionized epoch). We derive an alternative, quasi-linear formulation which improves upon the accuracy of the linear theory. (7) We describe and test two numerical schemes to calculate the 21-cm signal from reionization simulations to incorporate peculiar velocity effects in the optically thin approximation accurately, by real- to redshift-space re-mapping of the HI density. One is particle based, the other grid based, and while the former is most accurate, we demonstrate that the latter is computationally more efficient and can be optimized so as to achieve sufficient accuracy.
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35.
  • Mao, Yi, et al. (författare)
  • The impact of inhomogeneous subgrid clumping on cosmic reionization
  • 2020
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 491:2, s. 1600-1621
  • Tidskriftsartikel (refereegranskat)abstract
    • Cosmic reionization was driven by the imbalance between early sources and sinks of ionizing radiation, both of which were dominated by small-scale structure and are thus usually treated in cosmological reionization simulations by subgrid modelling. The recombination rate of intergalactic hydrogen is customarily boosted by a subgrid clumping factor, < n(2)>/< n >(2), which corrects for unresolved fluctuations in gas density n on scales below the grid-spacing of coarse-grained simulations. We investigate in detail the impact of this inhomogeneous subgrid clumping on reionization and its observables, as follows: (1) Previous attempts generally underestimated the clumping factor because of insufficient mass resolution. We perform a high-resolution N-body simulation that resolves haloes down to the pre-reionization Jeans mass to derive the time-dependent, spatially varying local clumping factor and a fitting formula for its correlation with local overdensity. (2) We then perform a large-scale N-body and radiative transfer simulation that accounts for this inhomogeneous subgrid clumping by applying this clumping factor-overdensity correlation. Boosting recombination significantly slows the expansion of ionized regions, which delays completion of reionization and suppresses 21 cm power spectra on large scales in the later stages of reionization. (3) We also consider a simplified prescription in which the globally averaged, time-evolving clumping factor from the same high-resolution N-body simulation is applied uniformly to all cells in the reionization simulation, instead. Observables computed with this model agree fairly well with those from the inhomogeneous clumping model, e.g. predicting 21 cm power spectra to within 20 per cent error, suggesting it may be a useful approximation.
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36.
  • Park, Hyunbae, et al. (författare)
  • THE KINETIC SUNYAEV-ZEL'DOVICH EFFECT AS A PROBE OF THE PHYSICS OF COSMIC REIONIZATION : THE EFFECT OF SELF-REGULATED REIONIZATION
  • 2013
  • Ingår i: Astrophysical Journal. - 0004-637X .- 1538-4357. ; 769:2
  • Tidskriftsartikel (refereegranskat)abstract
    • We calculate the angular power spectrum of the cosmic microwave background temperature fluctuations induced by the kinetic Sunyaev-Zel'dovich (kSZ) effect from the epoch of reionization (EOR). We use detailed N-body+radiative-transfer simulations to follow inhomogeneous reionization of the intergalactic medium. For the first time, we take into account the self-regulation of reionization: star formation in low-mass dwarf galaxies (10(8) M-circle dot less than or similar to M less than or similar to 10(9) M-circle dot) or minihalos (10(5) M-circle dot less than or similar to M less than or similar to 10(8) M-circle dot) is suppressed if these halos form in the regions that were already ionized or Lyman-Werner dissociated. Some previous work suggested that the amplitude of the kSZ power spectrum from the EOR can be described by a two-parameter family: the epoch of half-ionization and the duration of reionization. However, we argue that this picture applies only to simple forms of the reionization history which are roughly symmetric about the half-ionization epoch. In self-regulated reionization, the universe begins to be ionized early, maintains a low level of ionization for an extended period, and then finishes reionization as soon as high-mass atomically cooling halos dominate. While inclusion of self-regulation affects the amplitude of the kSZ power spectrum only modestly (similar to 10%), it can change the duration of reionization by a factor of more than two. We conclude that the simple two-parameter family does not capture the effect of a physical, yet complex, reionization history caused by self-regulation. When added to the post-reionization kSZ contribution, our prediction for the total kSZ power spectrum is below the current upper bound from the South Pole Telescope. Therefore, the current upper bound on the kSZ effect from the EOR is consistent with our understanding of the physics of reionization.
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37.
  • Purrington, Kristen S., et al. (författare)
  • Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer
  • 2014
  • Ingår i: Carcinogenesis. - : Oxford University Press (OUP). - 0143-3334 .- 1460-2180. ; 35:5, s. 1012-1019
  • Tidskriftsartikel (refereegranskat)abstract
    • In a genome-wide scan, we show that 30 variants in 25 genomic regions are associated with risk of TN breast cancer. Women carrying many of the risk variants may have 4-fold increased risk relative to women with few variants.Triple-negative (TN) breast cancer is an aggressive subtype of breast cancer associated with a unique set of epidemiologic and genetic risk factors. We conducted a two-stage genome-wide association study of TN breast cancer (stage 1: 1529 TN cases, 3399 controls; stage 2: 2148 cases, 1309 controls) to identify loci that influence TN breast cancer risk. Variants in the 19p13.1 and PTHLH loci showed genome-wide significant associations (P < 5 x 10(-) (8)) in stage 1 and 2 combined. Results also suggested a substantial enrichment of significantly associated variants among the single nucleotide polymorphisms (SNPs) analyzed in stage 2. Variants from 25 of 74 known breast cancer susceptibility loci were also associated with risk of TN breast cancer (P < 0.05). Associations with TN breast cancer were confirmed for 10 loci (LGR6, MDM4, CASP8, 2q35, 2p24.1, TERT-rs10069690, ESR1, TOX3, 19p13.1, RALY), and we identified associations with TN breast cancer for 15 additional breast cancer loci (P < 0.05: PEX14, 2q24.1, 2q31.1, ADAM29, EBF1, TCF7L2, 11q13.1, 11q24.3, 12p13.1, PTHLH, NTN4, 12q24, BRCA2, RAD51L1-rs2588809, MKL1). Further, two SNPs independent of previously reported signals in ESR1 [rs12525163 odds ratio (OR) = 1.15, P = 4.9 x 10(-) (4)] and 19p13.1 (rs1864112 OR = 0.84, P = 1.8 x 10(-) (9)) were associated with TN breast cancer. A polygenic risk score (PRS) for TN breast cancer based on known breast cancer risk variants showed a 4-fold difference in risk between the highest and lowest PRS quintiles (OR = 4.03, 95% confidence interval 3.46-4.70, P = 4.8 x 10(-) (69)). This translates to an absolute risk for TN breast cancer ranging from 0.8% to 3.4%, suggesting that genetic variation may be used for TN breast cancer risk prediction.
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38.
  • Shapiro, Paul R., et al. (författare)
  • Nonlinear Peculiar Velocity and Inhomogeneous Reionization Spoil 21 cm Cosmology from the Epoch of Reionization?
  • 2013
  • Ingår i: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 110:15, s. 151301-
  • Tidskriftsartikel (refereegranskat)abstract
    • The 21 cm background from the epoch of reionization is a promising cosmological probe: line-of-sight velocity fluctuations distort redshift, so brightness fluctuations in Fourier space depend upon angle, which linear theory shows can separate cosmological from astrophysical information. Nonlinear fluctuations in ionization, density, and velocity change this, however. The validity and accuracy of the separation scheme are tested here for the first time, by detailed reionization simulations. The scheme works reasonably well early in reionization (<= 40% ionized), but not late (<= 80% ionized). DOI: 10.1103/PhysRevLett.110.151301
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39.
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40.
  • Shapiro, Paul R, et al. (författare)
  • The Theory and Simulation of the 21-cm Background from the Epoch of Reionization
  • 2008
  • Ingår i: THE EVOLUTION OF GALAXIES THROUGH THE NEUTRAL HYDROGEN WINDOW. AIP Conference Proceedings, Volume 1035. - : American Institute of Physics. ; , s. 68-74
  • Konferensbidrag (refereegranskat)abstract
    • The redshifted 21-cm line of distant neutral H atoms provides a probe of the cosmic ``dark ages'' and the epoch of reionization (``EOR'') which ended them, within the first billion years of cosmic time. The radio continuum produced by this redshifted line can be seen in absorption or emission against the cosmic microwave background (``CMB'') at meterwaves, yielding information about the thermal and ionization history of the universe and the primordial density perturbation spectrum that led to galaxy and large-scale structure formation. Observing this 21-cm background is a great challenge, as it is necessary to detect a diffuse signal at a brightness temperature that differs from that of the CMB at millikelvin levels and distinguish this from foreground continuum sources. A new generation of low-frequency radio arrays is currently under development to search for this background. Accurate theoretical predictions of the spectrum and anisotropy of this background, necessary to guide and interpret future observations, are also quite challenging. Toward this end, it is necessary to model the inhomogeneous reionization of the intergalactic medium and determine the spin temperature of the 21-cm transition and its variations in time and space as it decouples from the temperature of the CMB. In my talk, I summarized some of the theoretical progress in this area. Here, I will focus on just a few of the predictions for the 21-cm background from the EOR, based on our newest, large-scale simulations of patchy reionization. These simulations are the first with enough N-body particles (from 5 to 29 billion) and radiative transfer rays to resolve the formation of and trace the ionizing radiation from each of the millions of dwarf galaxies believed responsible for reionization, down to 108 Msolar, in a cubic volume large enough (90 and 163 comoving Mpc on a side) to make meaningful statistical predictions of the fluctuating 21-cm background.
  •  
41.
  • Shukla, Hemant, et al. (författare)
  • The effects of Lyman-limit systems on the evolution and observability of the epoch of reionization
  • 2016
  • Ingår i: Monthly notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 458:1, s. 135-150
  • Tidskriftsartikel (refereegranskat)abstract
    • We present the first large-scale, full radiative transfer simulations of the reionization of the intergalactic medium in the presence of Lyman-limit systems (LLSs). To illustrate the impact of LLS opacity, possibly missed by previous simulations, we add either a uniform or spatially varying hydrogen bound free opacity. This opacity, implemented as the mean free path (MFP) of the ionizing photons, extrapolates the observed, post-reionization redshift dependence into the epoch of reionization. In qualitative agreement with previous studies, we find that at late times the presence of LLSs slows down the ionization fronts, and alters the size distribution of H TT regions. We quantitatively characterize the size distribution and morphological evolution of H 11 regions and examine the effects of the LLSs on the redshifted 21-cm signal from the patchy reionization. The presence of LLSs extends the ionization history by Delta z similar to 0.8. The LLS absorbers significantly impede the late-time growth of the H u regions. The position dependent LLS distribution slows reionization further and additionally limits the late growth of the ionized regions. However, there is no 'freeze out' of the H II regions and the largest regions grow to the size of the simulation volume. The 21-cm power spectra show that at large scales the power drops by a factor of 2 for 50 per cent and 75 per cent ionization stages (at k = 0.1 hMp c(-1)) reflecting the limiting effect of the LLSs on the growth of ionized patches. The statistical observables such as the rms of the brightness temperature fluctuations and the peak amplitudes of the 21-cm power spectra at large scales (k = 0.05-0.1 hMp c(-1)) are diminished by the presence of LLS.
  •  
42.
  • Zackrisson, Erik, et al. (författare)
  • Observational constraints on supermassive dark stars
  • 2010
  • Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1745-3925 .- 1365-2966. ; 407:1, s. L74-L78
  • Tidskriftsartikel (refereegranskat)abstract
    • Some of the first stars could be cooler and more massive than standard stellar models would suggest, due to the effects of dark matter annihilation in their cores. It has recently been argued that such objects may attain masses in the 104-107Msolar range and that such supermassive dark stars should be within reach of the upcoming James Webb Space Telescope. Notwithstanding theoretical difficulties with this proposal, we argue here that some of these objects should also be readily detectable with both the Hubble Space Telescope and ground-based 8-10 m class telescopes. Existing survey data already place strong constraints on 107Msolar dark stars at z ~ 10. We show that such objects must be exceedingly rare or short lived to have avoided detection.
  •  
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